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Ownership Document
|
| Schema Version: X0508 |
| Document Type: 4 |
| Period of Report: 9/26/23 |
| Not Subject to Section 16: 0 |
| Issuer: |
| Issuer CIK: 874015 |
| Issuer Name: IONIS PHARMACEUTICALS INC |
| Issuer Trading Symbol: IONS |
| Reporting Owner: |
| Reporting Owner ID: |
| | Owner CIK: 1073385 |
| | Owner Name: PARSHALL B LYNNE |
| Reporting Owner Address: |
| | Owner Street 1: 2855 GAZELLE COURT |
| | Owner Street 2: |
| | Owner City: CARLSBAD |
| | Owner State: CA |
| | Owner ZIP Code: 92010 |
| | Owner State Description: |
| Reporting Owner Relationship: |
| | Is Director? Yes |
| | Is Officer? No |
| | Is Ten Percent Owner? No |
| | Is Other? No |
| Aff 10b5 One: 1 |
| Non-Derivative Table: |
| Non-Derivative Transaction: |
| | Security Title: |
| | | Value: Common Stock |
| | Transaction Date: |
| | | Value: 9/26/23 |
| | Transaction Coding: |
| | | Transaction Form Type: 4 |
| | | Transaction Code: S |
| | | Equity Swap Involved? No |
| | Transaction Amounts: |
| | | Transaction Shares: |
| Value: 10,000 |
| Footnote ID: F1 |
| | | Transaction Price Per Share: |
| Value: 45.1268 |
| Footnote ID: F2 |
| | | Transaction Acquired-Disposed Code: |
| Value: D |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 82,588 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: D |
| Footnotes: |
| Footnote - F1: Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on November 16, 2022 |
| Footnote - F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.05 to $45.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4 |
| Owner Signature: |
| Signature Name: By: Patrick R. O'Neil, attorney-in-fact For: B. Lynne Parshall |
| Signature Date: 9/28/23 |
