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Ownership Document |
Schema Version: X0508 |
Document Type: 4 |
Period of Report: 2/9/23 |
Issuer: |
| Issuer CIK: 1785173 |
| Issuer Name: 89bio, Inc. |
| Issuer Trading Symbol: ETNB |
Reporting Owner: |
| Reporting Owner ID: |
| | Owner CIK: 1346824 |
| | Owner Name: RA CAPITAL MANAGEMENT, L.P. |
| Reporting Owner Address: |
| | Owner Street 1: 200 BERKELEY STREET, 18TH FLOOR |
| | Owner Street 2: |
| | Owner City: BOSTON |
| | Owner State: MA |
| | Owner ZIP Code: 02116 |
| | Owner State Description: |
| Reporting Owner Relationship: |
| | Is Director? Yes |
| | Is Officer? No |
| | Is Ten Percent Owner? Yes |
| | Is Other? No |
| | Officer Title: |
| | Other Text: |
Reporting Owner: |
| Reporting Owner ID: |
| | Owner CIK: 1315082 |
| | Owner Name: RA Capital Healthcare Fund LP |
| Reporting Owner Address: |
| | Owner Street 1: 200 BERKELEY STREET, 18TH FLOOR |
| | Owner Street 2: |
| | Owner City: BOSTON |
| | Owner State: MA |
| | Owner ZIP Code: 02116 |
| | Owner State Description: |
| Reporting Owner Relationship: |
| | Is Director? Yes |
| | Is Officer? No |
| | Is Ten Percent Owner? Yes |
| | Is Other? No |
| | Officer Title: |
| | Other Text: |
Reporting Owner: |
| Reporting Owner ID: |
| | Owner CIK: 1780117 |
| | Owner Name: RA Capital Nexus Fund, L.P. |
| Reporting Owner Address: |
| | Owner Street 1: 200 BERKELEY STREET, 18TH FLOOR |
| | Owner Street 2: |
| | Owner City: BOSTON |
| | Owner State: MA |
| | Owner ZIP Code: 02116 |
| | Owner State Description: |
| Reporting Owner Relationship: |
| | Is Director? Yes |
| | Is Officer? No |
| | Is Ten Percent Owner? Yes |
| | Is Other? No |
| | Officer Title: |
| | Other Text: |
Reporting Owner: |
| Reporting Owner ID: |
| | Owner CIK: 1384859 |
| | Owner Name: Kolchinsky Peter |
| Reporting Owner Address: |
| | Owner Street 1: C/O RA CAPITAL MANAGEMENT, L.P. |
| | Owner Street 2: 200 BERKELEY STREET, 18TH FLOOR |
| | Owner City: BOSTON |
| | Owner State: MA |
| | Owner ZIP Code: 02116 |
| | Owner State Description: |
| Reporting Owner Relationship: |
| | Is Director? Yes |
| | Is Officer? No |
| | Is Ten Percent Owner? Yes |
| | Is Other? No |
| | Officer Title: |
| | Other Text: |
Reporting Owner: |
| Reporting Owner ID: |
| | Owner CIK: 1619841 |
| | Owner Name: Shah Rajeev M. |
| Reporting Owner Address: |
| | Owner Street 1: C/O RA CAPITAL MANAGEMENT, L.P. |
| | Owner Street 2: 200 BERKELEY STREET, 18TH FLOOR |
| | Owner City: BOSTON |
| | Owner State: MA |
| | Owner ZIP Code: 02116 |
| | Owner State Description: |
| Reporting Owner Relationship: |
| | Is Director? Yes |
| | Is Officer? No |
| | Is Ten Percent Owner? Yes |
| | Is Other? No |
| | Officer Title: |
| | Other Text: |
Aff 10b5 One: 0 |
Non-Derivative Table: |
| Non-Derivative Transaction: |
| | Security Title: |
| | | Value: Common Stock |
| | Transaction Date: |
| | | Value: 4/11/24 |
| | Transaction Coding: |
| | | Transaction Form Type: 4 |
| | | Transaction Code: X |
| | | Equity Swap Involved? No |
| | Transaction Amounts: |
| | | Transaction Shares: |
| Value: 1,408,450 |
| | | Transaction Price Per Share: |
| Value: 5.325 |
| | | Transaction Acquired-Disposed Code: |
| Value: A |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 13,840,034 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: I |
| | | Nature of Ownership: |
| Value: See Footnotes |
| Footnote ID: F1 |
| Footnote ID: F2 |
| Non-Derivative Holding: |
| | Security Title: |
| | | Value: Common Stock |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 335,364 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: I |
| | | Nature of Ownership: |
| Value: See Footnotes |
| Footnote ID: F2 |
| Footnote ID: F3 |
Derivative Table: |
| Derivative Transaction: |
| | Security Title: |
| | | Value: Stock Option (Right to Buy) |
| | Conversion or Exercise Price: |
| | | Value: 14.7 |
| | Transaction Date: |
| | | Value: 2/9/23 |
| | Transaction Coding: |
| | | Transaction Form Type: 4 |
| | | Transaction Code: A |
| | | Equity Swap Involved? No |
| | Transaction Amounts: |
| | | Transaction Shares: |
| Value: 27,400 |
| | | Transaction Price Per Share: |
| Value: 0 |
| | | Transaction Acquired-Disposed Code: |
| Value: A |
| | Exercise Date: |
| | | Footnote ID: F4 |
| | Expiration Date: |
| | | Value: 2/9/33 |
| | Underlying Security: |
| | | Underlying Security Title: |
| Value: Common Stock |
| | | Underlying Security Shares: |
| Value: 27,400 |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 27,400 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: I |
| | | Nature of Ownership: |
| Value: See footnotes |
| Footnote ID: F2 |
| Footnote ID: F5 |
| Derivative Transaction: |
| | Security Title: |
| | | Value: Stock Option (Right to Buy) |
| | Conversion or Exercise Price: |
| | | Value: 9.98 |
| | Transaction Date: |
| | | Value: 2/1/24 |
| | Transaction Coding: |
| | | Transaction Form Type: 4 |
| | | Transaction Code: A |
| | | Equity Swap Involved? No |
| | Transaction Amounts: |
| | | Transaction Shares: |
| Value: 45,150 |
| | | Transaction Price Per Share: |
| Value: 0 |
| | | Transaction Acquired-Disposed Code: |
| Value: A |
| | Exercise Date: |
| | | Footnote ID: F6 |
| | Expiration Date: |
| | | Value: 2/1/34 |
| | Underlying Security: |
| | | Underlying Security Title: |
| Value: Common Stock |
| | | Underlying Security Shares: |
| Value: 45,150 |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 45,150 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: I |
| | | Nature of Ownership: |
| Value: See footnotes |
| Footnote ID: F2 |
| Footnote ID: F5 |
| Derivative Transaction: |
| | Security Title: |
| | | Value: Warrants (Right to Buy) |
| | Conversion or Exercise Price: |
| | | Value: 5.325 |
| | Transaction Date: |
| | | Value: 4/11/24 |
| | Transaction Coding: |
| | | Transaction Form Type: 4 |
| | | Transaction Code: X |
| | | Equity Swap Involved? No |
| | Transaction Amounts: |
| | | Transaction Shares: |
| Value: 2,816,900 |
| | | Transaction Price Per Share: |
| Value: 0 |
| | | Transaction Acquired-Disposed Code: |
| Value: D |
| | Exercise Date: |
| | | Value: 7/1/22 |
| | Expiration Date: |
| | | Value: 7/1/24 |
| | Underlying Security: |
| | | Underlying Security Title: |
| Value: Common Stock |
| | | Underlying Security Shares: |
| Value: 1,408,450 |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 0 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: I |
| | | Nature of Ownership: |
| Value: See footnotes |
| Footnote ID: F1 |
| Footnote ID: F2 |
Footnotes: |
| Footnote - F1: Held directly by the RA Capital Healthcare Fund, L.P. (the "Fund"). |
| Footnote - F2: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and RA Capital Nexus Fund, L.P. (the "Nexus Fund"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein. |
| Footnote - F3: Held directly by the Nexus Fund. |
| Footnote - F4: This option represents a right to purchase a total of 27,400 shares of the Issuer's Common Stock, which vested in full on February 9, 2024. |
| Footnote - F5: Under Dr. DiRocco's arrangement with the Adviser, Dr. DiRocco holds the option for the benefit of the Fund and the Nexus Fund. Dr. DiRocco is obligated to turn over to the Adviser any net cash or stock received upon exercise of the option, which will offset advisory fees owed by the Fund and the Nexus Fund to the Adviser. The Reporting Persons therefore disclaim beneficial ownership of the option and underlying common stock. |
| Footnote - F6: This option represents a right to purchase a total of 45,150 shares of the Issuer's Common Stock, which will vest in full on February 1, 2025, subject to Dr. Derek DiRocco's continuous service to the Issuer through such date. |
Remarks: Dr. Derek DiRocco, a Partner of the Adviser, serves on the Issuer's board of directors. The grants of the stock options reported herein were timely reported by Dr. DiRocco on Forms 4 filed by Dr. DiRocco on February 13, 2023 and February 5, 2024; however, the grants were inadvertently not reported by the Reporting Persons by virtue of an administrative error. |
Owner Signature: |
| Signature Name: /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P. |
| Signature Date: 4/15/24 |
Owner Signature: |
| Signature Name: /s/ Peter Kolchinsky, Manager of RA Capital Healthcare Fund GP, LLC the General Partner of RA Capital Healthcare Fund, L.P. |
| Signature Date: 4/15/24 |
Owner Signature: |
| Signature Name: /s/ Peter Kolchinsky, Manager of RA Capital Nexus Fund GP, LLC the General Partner of RA Capital Nexus Fund, L.P. |
| Signature Date: 4/15/24 |
Owner Signature: |
| Signature Name: /s/ Peter Kolchinsky, individually |
| Signature Date: 4/15/24 |
Owner Signature: |
| Signature Name: /s/ Rajeev Shah, individually |
| Signature Date: 4/15/24 |