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Baillie Gifford & Co. – ‘13F-HR’ for 3/31/23 – ‘INFO-TABLE’

On:  Wednesday, 5/3/23, at 9:24am ET   ·   Effective:  5/3/23   ·   For:  3/31/23   ·   Accession #:  1088875-23-83   ·   File #:  28-04825

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  As Of               Filer                 Filing    For·On·As Docs:Size

 5/03/23  Baillie Gifford & Co.             13F-HR      3/31/23    2:444K

Quarterly Holdings and Combination Report by a Money Manager   —   Form 13F

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 13F-HR      Quarterly Holdings and Combination Report by a      HTML      5K 
                Money Manager -- primary_doc.xml/2.2                             
 2: INFO-TABLE  Portfolio Securities Holdings Info Table --         HTML    442K 
                edgbgcomar23.xml

‘INFO-TABLE’   —   Portfolio Securities Holdings Info Table — edgbgcomar23.xml



        

This ‘INFO-TABLE’ Document is an XML Data File that may be rendered in various formats:

  Information Table    –   Plain Text   –  SEC Website  –  EDGAR System  –    XML Data    –  <?xml?> File
 
 
Plain Text rendering:  Portfolio Securities Holdings Info Table
 
                                                                                                                                                                                
Information Table
 
Info Table:
Name of Issuer:  10X Genomics Inc Class A
Title of Class:  CL A COM
CUSIP:  88025U-10-9
Value:  134,354,315
Shrs or Prn Amt:
Ssh Prnamt:  2408215
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2408215
Shared:  0
None:  0
Info Table:
Name of Issuer:  10X Genomics Inc Class A
Title of Class:  CL A COM
CUSIP:  88025U-10-9
Value:  133,142,947
Shrs or Prn Amt:
Ssh Prnamt:  2386502
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2158586
Shared:  0
None:  227916
Info Table:
Name of Issuer:  10X Genomics Inc Class A
Title of Class:  CL A COM
CUSIP:  88025U-10-9
Value:  77,495,211
Shrs or Prn Amt:
Ssh Prnamt:  1389052
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1136982
Shared:  0
None:  252070
Info Table:
Name of Issuer:  10X Genomics Inc Class A
Title of Class:  CL A COM
CUSIP:  88025U-10-9
Value:  143,392,462
Shrs or Prn Amt:
Ssh Prnamt:  2570218
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2255751
Shared:  0
None:  314467
Info Table:
Name of Issuer:  2seventy bio
Title of Class:  COM
CUSIP:  901384-10-7
Value:  2,917
Shrs or Prn Amt:
Ssh Prnamt:  286
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  286
Shared:  0
None:  0
Info Table:
Name of Issuer:  8x8 Inc
Title of Class:  COM
CUSIP:  282914-10-0
Value:  8,528
Shrs or Prn Amt:
Ssh Prnamt:  2045
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2045
Shared:  0
None:  0
Info Table:
Name of Issuer:  908 Devices
Title of Class:  COM
CUSIP:  65443P-10-2
Value:  2,141
Shrs or Prn Amt:
Ssh Prnamt:  249
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  249
Shared:  0
None:  0
Info Table:
Name of Issuer:  A. O. Smith
Title of Class:  COM
CUSIP:  831865-20-9
Value:  19,984
Shrs or Prn Amt:
Ssh Prnamt:  289
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  289
Shared:  0
None:  0
Info Table:
Name of Issuer:  ACM Research
Title of Class:  COM
CUSIP:  00108J-10-9
Value:  7,722
Shrs or Prn Amt:
Ssh Prnamt:  660
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  660
Shared:  0
None:  0
Info Table:
Name of Issuer:  AJ Gallagher & Co
Title of Class:  COM
CUSIP:  363576-10-9
Value:  305,542,349
Shrs or Prn Amt:
Ssh Prnamt:  1597106
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1423214
Shared:  0
None:  173892
Info Table:
Name of Issuer:  AJ Gallagher & Co
Title of Class:  COM
CUSIP:  363576-10-9
Value:  128,318,313
Shrs or Prn Amt:
Ssh Prnamt:  670735
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  670735
Shared:  0
None:  0
Info Table:
Name of Issuer:  AJ Gallagher & Co
Title of Class:  COM
CUSIP:  363576-10-9
Value:  82,276,118
Shrs or Prn Amt:
Ssh Prnamt:  430067
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  252949
Shared:  0
None:  177118
Info Table:
Name of Issuer:  AJ Gallagher & Co
Title of Class:  COM
CUSIP:  363576-10-9
Value:  354,049,382
Shrs or Prn Amt:
Ssh Prnamt:  1850658
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1221674
Shared:  0
None:  628984
Info Table:
Name of Issuer:  Abcam Plc ADR
Title of Class:  ADS
CUSIP:  000380-20-4
Value:  45,901,642
Shrs or Prn Amt:
Ssh Prnamt:  3410226
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3410226
Shared:  0
None:  0
Info Table:
Name of Issuer:  Abcam Plc ADR
Title of Class:  ADS
CUSIP:  000380-20-4
Value:  25,547,551
Shrs or Prn Amt:
Ssh Prnamt:  1898035
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  935374
Shared:  0
None:  962661
Info Table:
Name of Issuer:  Abcam Plc ADR
Title of Class:  ADS
CUSIP:  000380-20-4
Value:  88,997,924
Shrs or Prn Amt:
Ssh Prnamt:  6612030
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  3807375
Shared:  0
None:  2804655
Info Table:
Name of Issuer:  Abcellera Biologics Inc
Title of Class:  COM
CUSIP:  00288U-10-6
Value:  67,292,570
Shrs or Prn Amt:
Ssh Prnamt:  8924744
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  5912839
Shared:  0
None:  3011905
Info Table:
Name of Issuer:  Abcellera Biologics Inc
Title of Class:  COM
CUSIP:  00288U-10-6
Value:  35,715,314
Shrs or Prn Amt:
Ssh Prnamt:  4736779
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  4736779
Shared:  0
None:  0
Info Table:
Name of Issuer:  Abcellera Biologics Inc
Title of Class:  COM
CUSIP:  00288U-10-6
Value:  31,164,253
Shrs or Prn Amt:
Ssh Prnamt:  4133190
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  3339353
Shared:  0
None:  793837
Info Table:
Name of Issuer:  Abcellera Biologics Inc
Title of Class:  COM
CUSIP:  00288U-10-6
Value:  15,342,264
Shrs or Prn Amt:
Ssh Prnamt:  2034783
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1260789
Shared:  0
None:  773994
Info Table:
Name of Issuer:  Abcellera Biologics Inc
Title of Class:  COM
CUSIP:  00288U-10-6
Value:  1,169
Shrs or Prn Amt:
Ssh Prnamt:  155
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  155
Shared:  0
None:  0
Info Table:
Name of Issuer:  Acadia Pharmaceuticals Inc
Title of Class:  COM
CUSIP:  004225-10-8
Value:  11,631
Shrs or Prn Amt:
Ssh Prnamt:  618
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  618
Shared:  0
None:  0
Info Table:
Name of Issuer:  Accelerate Diagnostics
Title of Class:  COM
CUSIP:  00430H-10-2
Value:  293
Shrs or Prn Amt:
Ssh Prnamt:  418
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  418
Shared:  0
None:  0
Info Table:
Name of Issuer:  Accenture 'A'
Title of Class:  COM
CUSIP:  G1151C-10-1
Value:  13,719
Shrs or Prn Amt:
Ssh Prnamt:  48
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  48
Shared:  0
None:  0
Info Table:
Name of Issuer:  Acutus Medical
Title of Class:  COM
CUSIP:  005111-10-9
Value:  320
Shrs or Prn Amt:
Ssh Prnamt:  424
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  424
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adaptimmune Therapeutics ADR
Title of Class:  SPONDS ADR
CUSIP:  00653A-10-7
Value:  6,601,655
Shrs or Prn Amt:
Ssh Prnamt:  6056564
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  6056564
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adaptimmune Therapeutics ADR
Title of Class:  SPONDS ADR
CUSIP:  00653A-10-7
Value:  3,706,679
Shrs or Prn Amt:
Ssh Prnamt:  3400623
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1001605
Shared:  0
None:  2399018
Info Table:
Name of Issuer:  Adaptimmune Therapeutics ADR
Title of Class:  SPONDS ADR
CUSIP:  00653A-10-7
Value:  6,935,528
Shrs or Prn Amt:
Ssh Prnamt:  6362870
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  6362870
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adaptimmune Therapeutics ADR
Title of Class:  SPONDS ADR
CUSIP:  00653A-10-7
Value:  1,408,220
Shrs or Prn Amt:
Ssh Prnamt:  1291945
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1291945
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adeia Inc
Title of Class:  COM
CUSIP:  00676P-10-7
Value:  12,829
Shrs or Prn Amt:
Ssh Prnamt:  1448
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1448
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adicet Bio Inc
Title of Class:  COM
CUSIP:  007002-10-8
Value:  538,266
Shrs or Prn Amt:
Ssh Prnamt:  93449
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  93449
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adicet Bio Inc
Title of Class:  COM
CUSIP:  007002-10-8
Value:  507,900
Shrs or Prn Amt:
Ssh Prnamt:  88177
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  88177
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adobe Systems
Title of Class:  COM
CUSIP:  00724F-10-1
Value:  28,993,312
Shrs or Prn Amt:
Ssh Prnamt:  75235
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  41223
Shared:  0
None:  34012
Info Table:
Name of Issuer:  Adobe Systems
Title of Class:  COM
CUSIP:  00724F-10-1
Value:  108,133,666
Shrs or Prn Amt:
Ssh Prnamt:  280597
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  247528
Shared:  0
None:  33069
Info Table:
Name of Issuer:  Adobe Systems
Title of Class:  COM
CUSIP:  00724F-10-1
Value:  37,262,581
Shrs or Prn Amt:
Ssh Prnamt:  96693
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  96693
Shared:  0
None:  0
Info Table:
Name of Issuer:  Adobe Systems
Title of Class:  COM
CUSIP:  00724F-10-1
Value:  137,982,885
Shrs or Prn Amt:
Ssh Prnamt:  358053
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  235185
Shared:  0
None:  122868
Info Table:
Name of Issuer:  Advanced Drainage Systems
Title of Class:  COM
CUSIP:  00790R-10-4
Value:  29,835,182
Shrs or Prn Amt:
Ssh Prnamt:  354295
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  354295
Shared:  0
None:  0
Info Table:
Name of Issuer:  Advanced Drainage Systems
Title of Class:  COM
CUSIP:  00790R-10-4
Value:  79,270,073
Shrs or Prn Amt:
Ssh Prnamt:  941338
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  766858
Shared:  0
None:  174480
Info Table:
Name of Issuer:  Advanced Drainage Systems
Title of Class:  COM
CUSIP:  00790R-10-4
Value:  20,521,219
Shrs or Prn Amt:
Ssh Prnamt:  243691
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  137964
Shared:  0
None:  105727
Info Table:
Name of Issuer:  Advanced Drainage Systems
Title of Class:  COM
CUSIP:  00790R-10-4
Value:  86,479,628
Shrs or Prn Amt:
Ssh Prnamt:  1026952
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  671199
Shared:  0
None:  355753
Info Table:
Name of Issuer:  Advanced Micro Devices Inc
Title of Class:  COM
CUSIP:  007903-10-7
Value:  100,543,166
Shrs or Prn Amt:
Ssh Prnamt:  1025846
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  880449
Shared:  0
None:  145397
Info Table:
Name of Issuer:  Advanced Micro Devices Inc
Title of Class:  COM
CUSIP:  007903-10-7
Value:  527,134,142
Shrs or Prn Amt:
Ssh Prnamt:  5378371
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2223302
Shared:  0
None:  3155069
Info Table:
Name of Issuer:  Advanced Micro Devices Inc
Title of Class:  COM
CUSIP:  007903-10-7
Value:  60,857,251
Shrs or Prn Amt:
Ssh Prnamt:  620929
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  620929
Shared:  0
None:  0
Info Table:
Name of Issuer:  Advanced Micro Devices Inc
Title of Class:  COM
CUSIP:  007903-10-7
Value:  166,925,143
Shrs or Prn Amt:
Ssh Prnamt:  1703144
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  734783
Shared:  0
None:  968361
Info Table:
Name of Issuer:  Aerovironment
Title of Class:  COM
CUSIP:  008073-10-8
Value:  19,534,304
Shrs or Prn Amt:
Ssh Prnamt:  213117
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  213117
Shared:  0
None:  0
Info Table:
Name of Issuer:  Aerovironment
Title of Class:  COM
CUSIP:  008073-10-8
Value:  21,080,333
Shrs or Prn Amt:
Ssh Prnamt:  229984
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  66864
Shared:  0
None:  163120
Info Table:
Name of Issuer:  Aerovironment
Title of Class:  COM
CUSIP:  008073-10-8
Value:  8,485,150
Shrs or Prn Amt:
Ssh Prnamt:  92572
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  92572
Shared:  0
None:  0
Info Table:
Name of Issuer:  Aerovironment
Title of Class:  COM
CUSIP:  008073-10-8
Value:  20,217,171
Shrs or Prn Amt:
Ssh Prnamt:  220567
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  220567
Shared:  0
None:  0
Info Table:
Name of Issuer:  Affirm Holdings Inc Class A
Title of Class:  COM CL A
CUSIP:  00827B-10-6
Value:  35,512,660
Shrs or Prn Amt:
Ssh Prnamt:  3151079
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3151079
Shared:  0
None:  0
Info Table:
Name of Issuer:  Affirm Holdings Inc Class A
Title of Class:  COM CL A
CUSIP:  00827B-10-6
Value:  107,786,257
Shrs or Prn Amt:
Ssh Prnamt:  9563998
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6170236
Shared:  0
None:  3393762
Info Table:
Name of Issuer:  Affirm Holdings Inc Class A
Title of Class:  COM CL A
CUSIP:  00827B-10-6
Value:  69,159,358
Shrs or Prn Amt:
Ssh Prnamt:  6136589
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5108252
Shared:  0
None:  1028337
Info Table:
Name of Issuer:  Affirm Holdings Inc Class A
Title of Class:  COM CL A
CUSIP:  00827B-10-6
Value:  12,780,101
Shrs or Prn Amt:
Ssh Prnamt:  1133993
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  976404
Shared:  0
None:  157589
Info Table:
Name of Issuer:  Agios Pharmaceuticals Inc
Title of Class:  COM
CUSIP:  00847X-10-4
Value:  4,272
Shrs or Prn Amt:
Ssh Prnamt:  186
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  186
Shared:  0
None:  0
Info Table:
Name of Issuer:  Agnico Eagle Mines
Title of Class:  COM
CUSIP:  008474-10-8
Value:  1,913,822
Shrs or Prn Amt:
Ssh Prnamt:  37548
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  37548
Shared:  0
None:  0
Info Table:
Name of Issuer:  Agora Inc ADR
Title of Class:  ADS
CUSIP:  00851L-10-3
Value:  1,771,223
Shrs or Prn Amt:
Ssh Prnamt:  489288
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  489288
Shared:  0
None:  0
Info Table:
Name of Issuer:  Agora Inc ADR
Title of Class:  ADS
CUSIP:  00851L-10-3
Value:  923,143
Shrs or Prn Amt:
Ssh Prnamt:  255012
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  255012
Shared:  0
None:  0
Info Table:
Name of Issuer:  Akili Inc
Title of Class:  COM
CUSIP:  00974B-10-7
Value:  1,946,080
Shrs or Prn Amt:
Ssh Prnamt:  1216300
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1216300
Shared:  0
None:  0
Info Table:
Name of Issuer:  Akili Inc
Title of Class:  COM
CUSIP:  00974B-10-7
Value:  5,519,192
Shrs or Prn Amt:
Ssh Prnamt:  3449495
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  3449495
Shared:  0
None:  0
Info Table:
Name of Issuer:  Albemarle Corp
Title of Class:  COM
CUSIP:  012653-10-1
Value:  99,097,316
Shrs or Prn Amt:
Ssh Prnamt:  448323
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  448323
Shared:  0
None:  0
Info Table:
Name of Issuer:  Albemarle Corp
Title of Class:  COM
CUSIP:  012653-10-1
Value:  183,634,285
Shrs or Prn Amt:
Ssh Prnamt:  830774
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  734579
Shared:  0
None:  96195
Info Table:
Name of Issuer:  Albemarle Corp
Title of Class:  COM
CUSIP:  012653-10-1
Value:  54,763,986
Shrs or Prn Amt:
Ssh Prnamt:  247756
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  153372
Shared:  0
None:  94384
Info Table:
Name of Issuer:  Albemarle Corp
Title of Class:  COM
CUSIP:  012653-10-1
Value:  224,080,184
Shrs or Prn Amt:
Ssh Prnamt:  1013754
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  698569
Shared:  0
None:  315185
Info Table:
Name of Issuer:  Alector Inc
Title of Class:  COM
CUSIP:  014442-10-7
Value:  448,447
Shrs or Prn Amt:
Ssh Prnamt:  72447
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  72447
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alector Inc
Title of Class:  COM
CUSIP:  014442-10-7
Value:  1,081,114
Shrs or Prn Amt:
Ssh Prnamt:  174655
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  174655
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alector Inc
Title of Class:  COM
CUSIP:  014442-10-7
Value:  885,238
Shrs or Prn Amt:
Ssh Prnamt:  143011
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  143011
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alibaba Group Holding Sponsored ADR
Title of Class:  SPONSORED ADS
CUSIP:  01609W-10-2
Value:  3,985
Shrs or Prn Amt:
Ssh Prnamt:  39
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  39
Shared:  0
None:  0
Info Table:
Name of Issuer:  Allbirds Inc
Title of Class:  COM CL A
CUSIP:  01675A-10-9
Value:  639,000
Shrs or Prn Amt:
Ssh Prnamt:  532500
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  532500
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alnylam Pharmaceuticals
Title of Class:  COM
CUSIP:  02043Q-10-7
Value:  460,722,378
Shrs or Prn Amt:
Ssh Prnamt:  2299932
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2299932
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alnylam Pharmaceuticals
Title of Class:  COM
CUSIP:  02043Q-10-7
Value:  636,389,597
Shrs or Prn Amt:
Ssh Prnamt:  3176865
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2566146
Shared:  0
None:  610719
Info Table:
Name of Issuer:  Alnylam Pharmaceuticals
Title of Class:  COM
CUSIP:  02043Q-10-7
Value:  393,449,714
Shrs or Prn Amt:
Ssh Prnamt:  1964106
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1386035
Shared:  0
None:  578071
Info Table:
Name of Issuer:  Alnylam Pharmaceuticals
Title of Class:  COM
CUSIP:  02043Q-10-7
Value:  240,031,036
Shrs or Prn Amt:
Ssh Prnamt:  1198238
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  932360
Shared:  0
None:  265878
Info Table:
Name of Issuer:  Alphabet Inc Class A
Title of Class:  CAP STK CL A
CUSIP:  02079K-30-5
Value:  12,092,843
Shrs or Prn Amt:
Ssh Prnamt:  116580
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  116580
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alphabet Inc Class A
Title of Class:  CAP STK CL A
CUSIP:  02079K-30-5
Value:  29,041,703
Shrs or Prn Amt:
Ssh Prnamt:  279974
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  243890
Shared:  0
None:  36084
Info Table:
Name of Issuer:  Alphabet Inc Class A
Title of Class:  CAP STK CL A
CUSIP:  02079K-30-5
Value:  3,804,816
Shrs or Prn Amt:
Ssh Prnamt:  36680
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  23936
Shared:  0
None:  12744
Info Table:
Name of Issuer:  Alphabet Inc Class A
Title of Class:  CAP STK CL A
CUSIP:  02079K-30-5
Value:  72,152,721
Shrs or Prn Amt:
Ssh Prnamt:  695582
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  695582
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alphabet Inc Class C
Title of Class:  CAP STK CL C
CUSIP:  02079K-10-7
Value:  104,719,784
Shrs or Prn Amt:
Ssh Prnamt:  1006921
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1006921
Shared:  0
None:  0
Info Table:
Name of Issuer:  Alphabet Inc Class C
Title of Class:  CAP STK CL C
CUSIP:  02079K-10-7
Value:  335,676,016
Shrs or Prn Amt:
Ssh Prnamt:  3227654
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2878395
Shared:  0
None:  349259
Info Table:
Name of Issuer:  Alphabet Inc Class C
Title of Class:  CAP STK CL C
CUSIP:  02079K-10-7
Value:  309,519,496
Shrs or Prn Amt:
Ssh Prnamt:  2976149
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1698564
Shared:  0
None:  1277585
Info Table:
Name of Issuer:  Alphabet Inc Class C
Title of Class:  CAP STK CL C
CUSIP:  02079K-10-7
Value:  82,545,528
Shrs or Prn Amt:
Ssh Prnamt:  793707
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  434969
Shared:  0
None:  358738
Info Table:
Name of Issuer:  Alteryx Inc
Title of Class:  COM
CUSIP:  02156B-10-3
Value:  22,536
Shrs or Prn Amt:
Ssh Prnamt:  383
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  383
Shared:  0
None:  0
Info Table:
Name of Issuer:  Amazon.Com
Title of Class:  COM
CUSIP:  023135-10-6
Value:  519,945,747
Shrs or Prn Amt:
Ssh Prnamt:  5033844
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  5033844
Shared:  0
None:  0
Info Table:
Name of Issuer:  Amazon.Com
Title of Class:  COM
CUSIP:  023135-10-6
Value:  1,908,881,316
Shrs or Prn Amt:
Ssh Prnamt:  18480795
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  11476565
Shared:  0
None:  7004230
Info Table:
Name of Issuer:  Amazon.Com
Title of Class:  COM
CUSIP:  023135-10-6
Value:  335,175,430
Shrs or Prn Amt:
Ssh Prnamt:  3244994
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2559828
Shared:  0
None:  685166
Info Table:
Name of Issuer:  Amazon.Com
Title of Class:  COM
CUSIP:  023135-10-6
Value:  1,227,323,283
Shrs or Prn Amt:
Ssh Prnamt:  11882305
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  8544125
Shared:  0
None:  3338180
Info Table:
Name of Issuer:  Ambarella
Title of Class:  SHS
CUSIP:  G037AX-10-1
Value:  21,685,342
Shrs or Prn Amt:
Ssh Prnamt:  280100
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  280100
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ambarella
Title of Class:  SHS
CUSIP:  G037AX-10-1
Value:  14,411,888
Shrs or Prn Amt:
Ssh Prnamt:  186152
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  54075
Shared:  0
None:  132077
Info Table:
Name of Issuer:  Ambarella
Title of Class:  SHS
CUSIP:  G037AX-10-1
Value:  6,014,295
Shrs or Prn Amt:
Ssh Prnamt:  77684
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  77684
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ambarella
Title of Class:  SHS
CUSIP:  G037AX-10-1
Value:  7,556,579
Shrs or Prn Amt:
Ssh Prnamt:  97605
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  97605
Shared:  0
None:  0
Info Table:
Name of Issuer:  Amdocs
Title of Class:  COM
CUSIP:  G02602-10-3
Value:  41,485
Shrs or Prn Amt:
Ssh Prnamt:  432
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  432
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ameren
Title of Class:  COM
CUSIP:  023608-10-2
Value:  1,019,575
Shrs or Prn Amt:
Ssh Prnamt:  11802
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  11802
Shared:  0
None:  0
Info Table:
Name of Issuer:  American Superconductor Corp
Title of Class:  COM
CUSIP:  030111-20-7
Value:  3,551,747
Shrs or Prn Amt:
Ssh Prnamt:  723370
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  723370
Shared:  0
None:  0
Info Table:
Name of Issuer:  American Superconductor Corp
Title of Class:  COM
CUSIP:  030111-20-7
Value:  3,770,880
Shrs or Prn Amt:
Ssh Prnamt:  768000
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  768000
Shared:  0
None:  0
Info Table:
Name of Issuer:  American Tower Corp REIT
Title of Class:  COM
CUSIP:  03027X-10-0
Value:  13,519,134
Shrs or Prn Amt:
Ssh Prnamt:  66160
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  66160
Shared:  0
None:  0
Info Table:
Name of Issuer:  American Tower Corp REIT
Title of Class:  COM
CUSIP:  03027X-10-0
Value:  1,317,789
Shrs or Prn Amt:
Ssh Prnamt:  6449
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  6449
Shared:  0
None:  0
Info Table:
Name of Issuer:  American Well Corp Class A
Title of Class:  COM
CUSIP:  03044L-10-5
Value:  16,152
Shrs or Prn Amt:
Ssh Prnamt:  6844
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6844
Shared:  0
None:  0
Info Table:
Name of Issuer:  American Well Corp Class A
Title of Class:  COM
CUSIP:  03044L-10-5
Value:  228,974
Shrs or Prn Amt:
Ssh Prnamt:  97023
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  97023
Shared:  0
None:  0
Info Table:
Name of Issuer:  Amicus Therapeutics Inc
Title of Class:  COM
CUSIP:  03152W-10-9
Value:  5,966
Shrs or Prn Amt:
Ssh Prnamt:  538
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  538
Shared:  0
None:  0
Info Table:
Name of Issuer:  Amkor Technology
Title of Class:  COM
CUSIP:  031652-10-0
Value:  53,159
Shrs or Prn Amt:
Ssh Prnamt:  2043
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2043
Shared:  0
None:  0
Info Table:
Name of Issuer:  Analog Devices
Title of Class:  COM
CUSIP:  032654-10-5
Value:  126,513,080
Shrs or Prn Amt:
Ssh Prnamt:  641482
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  641482
Shared:  0
None:  0
Info Table:
Name of Issuer:  Analog Devices
Title of Class:  COM
CUSIP:  032654-10-5
Value:  219,171,967
Shrs or Prn Amt:
Ssh Prnamt:  1111307
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  989195
Shared:  0
None:  122112
Info Table:
Name of Issuer:  Analog Devices
Title of Class:  COM
CUSIP:  032654-10-5
Value:  66,542,620
Shrs or Prn Amt:
Ssh Prnamt:  337403
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  214898
Shared:  0
None:  122505
Info Table:
Name of Issuer:  Analog Devices
Title of Class:  COM
CUSIP:  032654-10-5
Value:  283,185,634
Shrs or Prn Amt:
Ssh Prnamt:  1435887
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  999643
Shared:  0
None:  436244
Info Table:
Name of Issuer:  Anterix
Title of Class:  COM
CUSIP:  03676C-10-0
Value:  5,352
Shrs or Prn Amt:
Ssh Prnamt:  162
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  162
Shared:  0
None:  0
Info Table:
Name of Issuer:  Apellis Pharmaceuticals
Title of Class:  COM
CUSIP:  03753U-10-6
Value:  21,437
Shrs or Prn Amt:
Ssh Prnamt:  325
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  325
Shared:  0
None:  0
Info Table:
Name of Issuer:  Appian Corp
Title of Class:  CL A
CUSIP:  03782L-10-1
Value:  19,100,398
Shrs or Prn Amt:
Ssh Prnamt:  430383
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  124063
Shared:  0
None:  306320
Info Table:
Name of Issuer:  Appian Corp
Title of Class:  CL A
CUSIP:  03782L-10-1
Value:  7,218,185
Shrs or Prn Amt:
Ssh Prnamt:  162645
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  162645
Shared:  0
None:  0
Info Table:
Name of Issuer:  Appian Corp
Title of Class:  CL A
CUSIP:  03782L-10-1
Value:  27,474,637
Shrs or Prn Amt:
Ssh Prnamt:  619077
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  619077
Shared:  0
None:  0
Info Table:
Name of Issuer:  Appian Corp
Title of Class:  CL A
CUSIP:  03782L-10-1
Value:  12,836,338
Shrs or Prn Amt:
Ssh Prnamt:  289237
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  289237
Shared:  0
None:  0
Info Table:
Name of Issuer:  Apple
Title of Class:  COM
CUSIP:  037833-10-0
Value:  58,714,624
Shrs or Prn Amt:
Ssh Prnamt:  356062
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  356062
Shared:  0
None:  0
Info Table:
Name of Issuer:  Apple
Title of Class:  COM
CUSIP:  037833-10-0
Value:  515,313
Shrs or Prn Amt:
Ssh Prnamt:  3125
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  3125
Info Table:
Name of Issuer:  Apple
Title of Class:  COM
CUSIP:  037833-10-0
Value:  12,704,391
Shrs or Prn Amt:
Ssh Prnamt:  77043
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  77043
Shared:  0
None:  0
Info Table:
Name of Issuer:  Apple
Title of Class:  COM
CUSIP:  037833-10-0
Value:  33,846,549
Shrs or Prn Amt:
Ssh Prnamt:  205255
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  205255
Shared:  0
None:  0
Info Table:
Name of Issuer:  Archer-Daniels-Midland Co
Title of Class:  COM
CUSIP:  039483-10-2
Value:  12,594,087
Shrs or Prn Amt:
Ssh Prnamt:  158098
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  158098
Shared:  0
None:  0
Info Table:
Name of Issuer:  Archer-Daniels-Midland Co
Title of Class:  COM
CUSIP:  039483-10-2
Value:  16,968
Shrs or Prn Amt:
Ssh Prnamt:  213
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  213
Shared:  0
None:  0
Info Table:
Name of Issuer:  Archer-Daniels-Midland Co
Title of Class:  COM
CUSIP:  039483-10-2
Value:  4,585,947
Shrs or Prn Amt:
Ssh Prnamt:  57569
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  57569
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ares Capital Corp
Title of Class:  COM
CUSIP:  04010L-10-3
Value:  20,667,709
Shrs or Prn Amt:
Ssh Prnamt:  1130928
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1130928
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ares Capital Corp
Title of Class:  COM
CUSIP:  04010L-10-3
Value:  3,422,524
Shrs or Prn Amt:
Ssh Prnamt:  187279
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  187279
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ascendis Pharma ADR 1:1
Title of Class:  SPON ADR
CUSIP:  04351P-10-1
Value:  1,786,285
Shrs or Prn Amt:
Ssh Prnamt:  16660
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  16660
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ascendis Pharma ADR 1:1
Title of Class:  SPON ADR
CUSIP:  04351P-10-1
Value:  3,686,224
Shrs or Prn Amt:
Ssh Prnamt:  34380
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  34380
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ascendis Pharma ADR 1:1
Title of Class:  SPON ADR
CUSIP:  04351P-10-1
Value:  4,358,815
Shrs or Prn Amt:
Ssh Prnamt:  40653
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  40653
Shared:  0
None:  0
Info Table:
Name of Issuer:  Asensus Surgical Inc
Title of Class:  COM
CUSIP:  04367G-10-3
Value:  3,499
Shrs or Prn Amt:
Ssh Prnamt:  5338
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  5338
Shared:  0
None:  0
Info Table:
Name of Issuer:  AstraZeneca ADR
Title of Class:  COM
CUSIP:  046353-10-8
Value:  31,651
Shrs or Prn Amt:
Ssh Prnamt:  456
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  456
Shared:  0
None:  0
Info Table:
Name of Issuer:  Atlassian Corp Plc
Title of Class:  CL A
CUSIP:  049468-10-1
Value:  248,632,983
Shrs or Prn Amt:
Ssh Prnamt:  1452550
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  629339
Shared:  0
None:  823211
Info Table:
Name of Issuer:  Atlassian Corp Plc
Title of Class:  CL A
CUSIP:  049468-10-1
Value:  151,508,216
Shrs or Prn Amt:
Ssh Prnamt:  885133
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  761190
Shared:  0
None:  123943
Info Table:
Name of Issuer:  Atlassian Corp Plc
Title of Class:  CL A
CUSIP:  049468-10-1
Value:  788,808,873
Shrs or Prn Amt:
Ssh Prnamt:  4608336
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1905527
Shared:  0
None:  2702809
Info Table:
Name of Issuer:  Atlassian Corp Plc
Title of Class:  CL A
CUSIP:  049468-10-1
Value:  90,758,956
Shrs or Prn Amt:
Ssh Prnamt:  530227
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  530227
Shared:  0
None:  0
Info Table:
Name of Issuer:  Aurora Innovation Class A Common
Title of Class:  COM CL A
CUSIP:  051774-10-7
Value:  20,753,341
Shrs or Prn Amt:
Ssh Prnamt:  14930461
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  14930461
Shared:  0
None:  0
Info Table:
Name of Issuer:  AutoZone
Title of Class:  COM
CUSIP:  053332-10-2
Value:  31,956
Shrs or Prn Amt:
Ssh Prnamt:  13
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  13
Shared:  0
None:  0
Info Table:
Name of Issuer:  AutoZone
Title of Class:  COM
CUSIP:  053332-10-2
Value:  6,354,318
Shrs or Prn Amt:
Ssh Prnamt:  2585
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2585
Shared:  0
None:  0
Info Table:
Name of Issuer:  AutoZone
Title of Class:  COM
CUSIP:  053332-10-2
Value:  7,760,380
Shrs or Prn Amt:
Ssh Prnamt:  3157
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  3157
Shared:  0
None:  0
Info Table:
Name of Issuer:  Autodesk
Title of Class:  COM
CUSIP:  052769-10-6
Value:  68,392,841
Shrs or Prn Amt:
Ssh Prnamt:  328559
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  328559
Shared:  0
None:  0
Info Table:
Name of Issuer:  Autodesk
Title of Class:  COM
CUSIP:  052769-10-6
Value:  42,400,319
Shrs or Prn Amt:
Ssh Prnamt:  203691
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  124792
Shared:  0
None:  78899
Info Table:
Name of Issuer:  Autodesk
Title of Class:  COM
CUSIP:  052769-10-6
Value:  67,273,149
Shrs or Prn Amt:
Ssh Prnamt:  323180
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  253508
Shared:  0
None:  69672
Info Table:
Name of Issuer:  Autodesk
Title of Class:  COM
CUSIP:  052769-10-6
Value:  20,193,185
Shrs or Prn Amt:
Ssh Prnamt:  97008
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  29794
Shared:  0
None:  67214
Info Table:
Name of Issuer:  Avery Dennison Corporation
Title of Class:  COM
CUSIP:  053611-10-9
Value:  23,619
Shrs or Prn Amt:
Ssh Prnamt:  132
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  132
Shared:  0
None:  0
Info Table:
Name of Issuer:  Axon Enterprise Inc
Title of Class:  COM
CUSIP:  05464C-10-1
Value:  95,074,450
Shrs or Prn Amt:
Ssh Prnamt:  422835
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  422835
Shared:  0
None:  0
Info Table:
Name of Issuer:  Axon Enterprise Inc
Title of Class:  COM
CUSIP:  05464C-10-1
Value:  183,639,717
Shrs or Prn Amt:
Ssh Prnamt:  816721
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  597848
Shared:  0
None:  218873
Info Table:
Name of Issuer:  Axon Enterprise Inc
Title of Class:  COM
CUSIP:  05464C-10-1
Value:  56,701,549
Shrs or Prn Amt:
Ssh Prnamt:  252175
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  176670
Shared:  0
None:  75505
Info Table:
Name of Issuer:  Axon Enterprise Inc
Title of Class:  COM
CUSIP:  05464C-10-1
Value:  196,204,560
Shrs or Prn Amt:
Ssh Prnamt:  872602
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  606737
Shared:  0
None:  265865
Info Table:
Name of Issuer:  Axonics Modulation Technologies
Title of Class:  COM
CUSIP:  05465P-10-1
Value:  10,803
Shrs or Prn Amt:
Ssh Prnamt:  198
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  198
Shared:  0
None:  0
Info Table:
Name of Issuer:  Baidu.com Sponsored ADR
Title of Class:  SPON ADR REP A
CUSIP:  056752-10-8
Value:  402,583,779
Shrs or Prn Amt:
Ssh Prnamt:  2667531
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2545239
Shared:  0
None:  122292
Info Table:
Name of Issuer:  Banco Bradesco Pn ADR
Title of Class:  SP ADR PFD NEW
CUSIP:  059460-30-3
Value:  120,369,277
Shrs or Prn Amt:
Ssh Prnamt:  45942472
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  27290173
Shared:  0
None:  18652299
Info Table:
Name of Issuer:  Banco Bradesco Pn ADR
Title of Class:  SP ADR PFD NEW
CUSIP:  059460-30-3
Value:  14,298,820
Shrs or Prn Amt:
Ssh Prnamt:  5457565
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  5457565
Shared:  0
None:  0
Info Table:
Name of Issuer:  Banco Bradesco Pn ADR
Title of Class:  SP ADR PFD NEW
CUSIP:  059460-30-3
Value:  11,205,114
Shrs or Prn Amt:
Ssh Prnamt:  4276761
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1443451
Shared:  0
None:  2833310
Info Table:
Name of Issuer:  Bandwidth
Title of Class:  COM
CUSIP:  05988J-10-3
Value:  12,054
Shrs or Prn Amt:
Ssh Prnamt:  793
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  793
Shared:  0
None:  0
Info Table:
Name of Issuer:  Bandwidth
Title of Class:  COM
CUSIP:  05988J-10-3
Value:  174,238
Shrs or Prn Amt:
Ssh Prnamt:  11463
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  11463
Shared:  0
None:  0
Info Table:
Name of Issuer:  Beam Therapeutics
Title of Class:  COM
CUSIP:  07373V-10-5
Value:  3,827,776
Shrs or Prn Amt:
Ssh Prnamt:  125009
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  125009
Shared:  0
None:  0
Info Table:
Name of Issuer:  Beam Therapeutics
Title of Class:  COM
CUSIP:  07373V-10-5
Value:  4,551,510
Shrs or Prn Amt:
Ssh Prnamt:  148645
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  42486
Shared:  0
None:  106159
Info Table:
Name of Issuer:  Beam Therapeutics
Title of Class:  COM
CUSIP:  07373V-10-5
Value:  1,601,487
Shrs or Prn Amt:
Ssh Prnamt:  52302
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  52302
Shared:  0
None:  0
Info Table:
Name of Issuer:  Beam Therapeutics
Title of Class:  COM
CUSIP:  07373V-10-5
Value:  3,882,769
Shrs or Prn Amt:
Ssh Prnamt:  126805
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  126805
Shared:  0
None:  0
Info Table:
Name of Issuer:  BeiGene Ltd
Title of Class:  SPONSORED ADR
CUSIP:  07725L-10-2
Value:  51,167,253
Shrs or Prn Amt:
Ssh Prnamt:  237402
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  237402
Shared:  0
None:  0
Info Table:
Name of Issuer:  BeiGene Ltd
Title of Class:  SPONSORED ADR
CUSIP:  07725L-10-2
Value:  142,424,164
Shrs or Prn Amt:
Ssh Prnamt:  660809
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  281566
Shared:  0
None:  379243
Info Table:
Name of Issuer:  BeiGene Ltd
Title of Class:  SPONSORED ADR
CUSIP:  07725L-10-2
Value:  81,849,888
Shrs or Prn Amt:
Ssh Prnamt:  379761
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  323842
Shared:  0
None:  55919
Info Table:
Name of Issuer:  BeiGene Ltd
Title of Class:  SPONSORED ADR
CUSIP:  07725L-10-2
Value:  439,549,727
Shrs or Prn Amt:
Ssh Prnamt:  2039390
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  837132
Shared:  0
None:  1202258
Info Table:
Name of Issuer:  Beyond Meat Inc
Title of Class:  COM
CUSIP:  08862E-10-9
Value:  72,077
Shrs or Prn Amt:
Ssh Prnamt:  4441
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  4441
Shared:  0
None:  0
Info Table:
Name of Issuer:  Beyond Meat Inc
Title of Class:  COM
CUSIP:  08862E-10-9
Value:  3,879
Shrs or Prn Amt:
Ssh Prnamt:  239
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  239
Shared:  0
None:  0
Info Table:
Name of Issuer:  BioCryst Pharmaceuticals
Title of Class:  COM
CUSIP:  09058V-10-3
Value:  14,070
Shrs or Prn Amt:
Ssh Prnamt:  1687
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1687
Shared:  0
None:  0
Info Table:
Name of Issuer:  BioNTech ADR
Title of Class:  SPONS ADS
CUSIP:  09075V-10-2
Value:  59,048,921
Shrs or Prn Amt:
Ssh Prnamt:  474022
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  474022
Shared:  0
None:  0
Info Table:
Name of Issuer:  BioNTech ADR
Title of Class:  SPONS ADS
CUSIP:  09075V-10-2
Value:  3,114
Shrs or Prn Amt:
Ssh Prnamt:  25
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  25
Shared:  0
None:  0
Info Table:
Name of Issuer:  BioNTech ADR
Title of Class:  SPONS ADS
CUSIP:  09075V-10-2
Value:  96,504,628
Shrs or Prn Amt:
Ssh Prnamt:  774702
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  690083
Shared:  0
None:  84619
Info Table:
Name of Issuer:  BioNTech ADR
Title of Class:  SPONS ADS
CUSIP:  09075V-10-2
Value:  622,006,910
Shrs or Prn Amt:
Ssh Prnamt:  4993232
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2371479
Shared:  0
None:  2621753
Info Table:
Name of Issuer:  BioNTech ADR
Title of Class:  SPONS ADS
CUSIP:  09075V-10-2
Value:  161,807,835
Shrs or Prn Amt:
Ssh Prnamt:  1298931
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  562263
Shared:  0
None:  736668
Info Table:
Name of Issuer:  Blackline
Title of Class:  COM
CUSIP:  09239B-10-9
Value:  9,746,688
Shrs or Prn Amt:
Ssh Prnamt:  145148
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  145148
Shared:  0
None:  0
Info Table:
Name of Issuer:  Blackline
Title of Class:  COM
CUSIP:  09239B-10-9
Value:  24,605,774
Shrs or Prn Amt:
Ssh Prnamt:  366430
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  106717
Shared:  0
None:  259713
Info Table:
Name of Issuer:  Blackline
Title of Class:  COM
CUSIP:  09239B-10-9
Value:  15,749,227
Shrs or Prn Amt:
Ssh Prnamt:  234538
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  234538
Shared:  0
None:  0
Info Table:
Name of Issuer:  Blackline
Title of Class:  COM
CUSIP:  09239B-10-9
Value:  17,725,787
Shrs or Prn Amt:
Ssh Prnamt:  263973
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  263973
Shared:  0
None:  0
Info Table:
Name of Issuer:  Blackrock Inc
Title of Class:  COM
CUSIP:  09247X-10-1
Value:  17,397
Shrs or Prn Amt:
Ssh Prnamt:  26
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  26
Shared:  0
None:  0
Info Table:
Name of Issuer:  Blink Charging
Title of Class:  COM
CUSIP:  09354A-10-0
Value:  3,425
Shrs or Prn Amt:
Ssh Prnamt:  396
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  396
Shared:  0
None:  0
Info Table:
Name of Issuer:  Block Inc
Title of Class:  COM
CUSIP:  852234-10-3
Value:  8,208,206
Shrs or Prn Amt:
Ssh Prnamt:  119566
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  119566
Shared:  0
None:  0
Info Table:
Name of Issuer:  Block Inc
Title of Class:  COM
CUSIP:  852234-10-3
Value:  14,417
Shrs or Prn Amt:
Ssh Prnamt:  210
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  210
Shared:  0
None:  0
Info Table:
Name of Issuer:  Block Inc
Title of Class:  COM
CUSIP:  852234-10-3
Value:  3,992,753
Shrs or Prn Amt:
Ssh Prnamt:  58161
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  58161
Shared:  0
None:  0
Info Table:
Name of Issuer:  Bluebird Bio Inc
Title of Class:  COM
CUSIP:  09609G-10-0
Value:  2,735
Shrs or Prn Amt:
Ssh Prnamt:  860
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  860
Shared:  0
None:  0
Info Table:
Name of Issuer:  Blueprint Medicines Corp
Title of Class:  COM
CUSIP:  09627Y-10-9
Value:  14,172
Shrs or Prn Amt:
Ssh Prnamt:  315
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  315
Shared:  0
None:  0
Info Table:
Name of Issuer:  Booking Holdings Inc
Title of Class:  COM
CUSIP:  09857L-10-8
Value:  57,310,623
Shrs or Prn Amt:
Ssh Prnamt:  21607
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  21607
Shared:  0
None:  0
Info Table:
Name of Issuer:  Booking Holdings Inc
Title of Class:  COM
CUSIP:  09857L-10-8
Value:  176,310,998
Shrs or Prn Amt:
Ssh Prnamt:  66472
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  58987
Shared:  0
None:  7485
Info Table:
Name of Issuer:  Booking Holdings Inc
Title of Class:  COM
CUSIP:  09857L-10-8
Value:  45,393,345
Shrs or Prn Amt:
Ssh Prnamt:  17114
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  9400
Shared:  0
None:  7714
Info Table:
Name of Issuer:  Booking Holdings Inc
Title of Class:  COM
CUSIP:  09857L-10-8
Value:  210,646,445
Shrs or Prn Amt:
Ssh Prnamt:  79417
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  52015
Shared:  0
None:  27402
Info Table:
Name of Issuer:  Boston Omaha
Title of Class:  COM
CUSIP:  101044-10-5
Value:  16,001
Shrs or Prn Amt:
Ssh Prnamt:  676
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  676
Shared:  0
None:  0
Info Table:
Name of Issuer:  Box Inc
Title of Class:  COM
CUSIP:  10316T-10-4
Value:  28,049
Shrs or Prn Amt:
Ssh Prnamt:  1047
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1047
Shared:  0
None:  0
Info Table:
Name of Issuer:  Bristol Myers Squibb
Title of Class:  COM
CUSIP:  110122-10-8
Value:  36,804
Shrs or Prn Amt:
Ssh Prnamt:  531
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  531
Shared:  0
None:  0
Info Table:
Name of Issuer:  Broadridge Finl.Sltn.
Title of Class:  COM
CUSIP:  11133T-10-3
Value:  55,406,538
Shrs or Prn Amt:
Ssh Prnamt:  378021
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  378021
Shared:  0
None:  0
Info Table:
Name of Issuer:  Broadridge Finl.Sltn.
Title of Class:  COM
CUSIP:  11133T-10-3
Value:  172,403,549
Shrs or Prn Amt:
Ssh Prnamt:  1176254
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1046900
Shared:  0
None:  129354
Info Table:
Name of Issuer:  Broadridge Finl.Sltn.
Title of Class:  COM
CUSIP:  11133T-10-3
Value:  43,759,646
Shrs or Prn Amt:
Ssh Prnamt:  298558
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  164725
Shared:  0
None:  133833
Info Table:
Name of Issuer:  Broadridge Finl.Sltn.
Title of Class:  COM
CUSIP:  11133T-10-3
Value:  192,029,272
Shrs or Prn Amt:
Ssh Prnamt:  1310154
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  837724
Shared:  0
None:  472430
Info Table:
Name of Issuer:  Brookfield Renewable
Title of Class:  COM
CUSIP:  11284V-10-5
Value:  28,031,053
Shrs or Prn Amt:
Ssh Prnamt:  802033
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  802033
Shared:  0
None:  0
Info Table:
Name of Issuer:  Brookfield Renewable
Title of Class:  COM
CUSIP:  11284V-10-5
Value:  3,249,511
Shrs or Prn Amt:
Ssh Prnamt:  92976
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  92976
Shared:  0
None:  0
Info Table:
Name of Issuer:  Brunswick Corp
Title of Class:  COM
CUSIP:  117043-10-9
Value:  19,926
Shrs or Prn Amt:
Ssh Prnamt:  243
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  243
Shared:  0
None:  0
Info Table:
Name of Issuer:  Bumble Inc
Title of Class:  COM CL A
CUSIP:  12047B-10-5
Value:  7,055,478
Shrs or Prn Amt:
Ssh Prnamt:  360894
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  360894
Shared:  0
None:  0
Info Table:
Name of Issuer:  Burford Capital
Title of Class:  ORD SHS
CUSIP:  G17977-11-0
Value:  10,101,038
Shrs or Prn Amt:
Ssh Prnamt:  1082755
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1082755
Shared:  0
None:  0
Info Table:
Name of Issuer:  Burford Capital
Title of Class:  ORD SHS
CUSIP:  G17977-11-0
Value:  6,640,452
Shrs or Prn Amt:
Ssh Prnamt:  711807
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  625973
Shared:  0
None:  85834
Info Table:
Name of Issuer:  Burning Rock Biotech Ltd ADR
Title of Class:  SPON ADS
CUSIP:  12233L-10-7
Value:  450,109
Shrs or Prn Amt:
Ssh Prnamt:  160181
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  160181
Shared:  0
None:  0
Info Table:
Name of Issuer:  C3.ai
Title of Class:  CL A
CUSIP:  12468P-10-4
Value:  3,928
Shrs or Prn Amt:
Ssh Prnamt:  117
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  117
Shared:  0
None:  0
Info Table:
Name of Issuer:  CEVA Inc
Title of Class:  COM
CUSIP:  157210-10-5
Value:  3,526,228
Shrs or Prn Amt:
Ssh Prnamt:  115880
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  115880
Shared:  0
None:  0
Info Table:
Name of Issuer:  CEVA Inc
Title of Class:  COM
CUSIP:  157210-10-5
Value:  2,510,475
Shrs or Prn Amt:
Ssh Prnamt:  82500
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  82500
Shared:  0
None:  0
Info Table:
Name of Issuer:  CEVA Inc
Title of Class:  COM
CUSIP:  157210-10-5
Value:  1,908,691
Shrs or Prn Amt:
Ssh Prnamt:  62724
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  62724
Shared:  0
None:  0
Info Table:
Name of Issuer:  CEVA Inc
Title of Class:  COM
CUSIP:  157210-10-5
Value:  4,224,445
Shrs or Prn Amt:
Ssh Prnamt:  138825
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  41393
Shared:  0
None:  97432
Info Table:
Name of Issuer:  CIA Cervecerias Unidas ADR
Title of Class:  SPONSORED ADR
CUSIP:  204429-10-4
Value:  5,593,977
Shrs or Prn Amt:
Ssh Prnamt:  357900
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  0
Shared:  0
None:  357900
Info Table:
Name of Issuer:  CRH Plc ADR
Title of Class:  ADR
CUSIP:  12626K-20-3
Value:  10,734
Shrs or Prn Amt:
Ssh Prnamt:  211
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  211
Shared:  0
None:  0
Info Table:
Name of Issuer:  CS Disco Inc
Title of Class:  COM
CUSIP:  126327-10-5
Value:  228,403
Shrs or Prn Amt:
Ssh Prnamt:  34398
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  34398
Shared:  0
None:  0
Info Table:
Name of Issuer:  CS Disco Inc
Title of Class:  COM
CUSIP:  126327-10-5
Value:  16,095
Shrs or Prn Amt:
Ssh Prnamt:  2424
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2424
Shared:  0
None:  0
Info Table:
Name of Issuer:  Calix Inc
Title of Class:  COM
CUSIP:  13100M-50-9
Value:  524,860
Shrs or Prn Amt:
Ssh Prnamt:  9794
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  9794
Shared:  0
None:  0
Info Table:
Name of Issuer:  Calix Inc
Title of Class:  COM
CUSIP:  13100M-50-9
Value:  37,406
Shrs or Prn Amt:
Ssh Prnamt:  698
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  698
Shared:  0
None:  0
Info Table:
Name of Issuer:  Canadian Pacific Railway
Title of Class:  COM
CUSIP:  13645T-10-0
Value:  111,178,996
Shrs or Prn Amt:
Ssh Prnamt:  1445797
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1219940
Shared:  0
None:  225857
Info Table:
Name of Issuer:  Cardlytics Inc
Title of Class:  COM
CUSIP:  14161W-10-5
Value:  1,337,372
Shrs or Prn Amt:
Ssh Prnamt:  393924
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  393924
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cardlytics Inc
Title of Class:  COM
CUSIP:  14161W-10-5
Value:  898,059
Shrs or Prn Amt:
Ssh Prnamt:  264524
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  264524
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cardlytics Inc
Title of Class:  COM
CUSIP:  14161W-10-5
Value:  763,189
Shrs or Prn Amt:
Ssh Prnamt:  224798
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  224798
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cardlytics Inc
Title of Class:  COM
CUSIP:  14161W-10-5
Value:  1,845,845
Shrs or Prn Amt:
Ssh Prnamt:  543695
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  160589
Shared:  0
None:  383106
Info Table:
Name of Issuer:  Cargurus Inc
Title of Class:  COM
CUSIP:  141788-10-9
Value:  39,490
Shrs or Prn Amt:
Ssh Prnamt:  2114
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2114
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cargurus Inc
Title of Class:  COM
CUSIP:  141788-10-9
Value:  559,373
Shrs or Prn Amt:
Ssh Prnamt:  29945
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  29945
Shared:  0
None:  0
Info Table:
Name of Issuer:  Carmax Inc
Title of Class:  COM
CUSIP:  143130-10-2
Value:  6,196,335
Shrs or Prn Amt:
Ssh Prnamt:  96396
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  96396
Shared:  0
None:  0
Info Table:
Name of Issuer:  Carmax Inc
Title of Class:  COM
CUSIP:  143130-10-2
Value:  17,227
Shrs or Prn Amt:
Ssh Prnamt:  268
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  268
Shared:  0
None:  0
Info Table:
Name of Issuer:  Carmax Inc
Title of Class:  COM
CUSIP:  143130-10-2
Value:  4,703,560
Shrs or Prn Amt:
Ssh Prnamt:  73173
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  73173
Shared:  0
None:  0
Info Table:
Name of Issuer:  Carvana
Title of Class:  COM
CUSIP:  146869-10-2
Value:  31,595,815
Shrs or Prn Amt:
Ssh Prnamt:  3227356
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2043968
Shared:  0
None:  1183388
Info Table:
Name of Issuer:  Carvana
Title of Class:  COM
CUSIP:  146869-10-2
Value:  78,367,912
Shrs or Prn Amt:
Ssh Prnamt:  8004894
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4008839
Shared:  0
None:  3996055
Info Table:
Name of Issuer:  Carvana
Title of Class:  COM
CUSIP:  146869-10-2
Value:  16,388,812
Shrs or Prn Amt:
Ssh Prnamt:  1674036
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1674036
Shared:  0
None:  0
Info Table:
Name of Issuer:  Carvana
Title of Class:  COM
CUSIP:  146869-10-2
Value:  11,275,946
Shrs or Prn Amt:
Ssh Prnamt:  1151782
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  969267
Shared:  0
None:  182515
Info Table:
Name of Issuer:  Castle Biosciences
Title of Class:  COM
CUSIP:  14843C-10-5
Value:  5,112
Shrs or Prn Amt:
Ssh Prnamt:  225
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  225
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cbre Group Inc
Title of Class:  CL A
CUSIP:  12504L-10-9
Value:  44,944,594
Shrs or Prn Amt:
Ssh Prnamt:  617286
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  617286
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cbre Group Inc
Title of Class:  CL A
CUSIP:  12504L-10-9
Value:  159,863,529
Shrs or Prn Amt:
Ssh Prnamt:  2195626
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1431429
Shared:  0
None:  764197
Info Table:
Name of Issuer:  Cbre Group Inc
Title of Class:  CL A
CUSIP:  12504L-10-9
Value:  35,928,677
Shrs or Prn Amt:
Ssh Prnamt:  493458
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  273771
Shared:  0
None:  219687
Info Table:
Name of Issuer:  Cbre Group Inc
Title of Class:  CL A
CUSIP:  12504L-10-9
Value:  154,557,719
Shrs or Prn Amt:
Ssh Prnamt:  2122754
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1905127
Shared:  0
None:  217627
Info Table:
Name of Issuer:  Cellectis ADR
Title of Class:  SPONS ADS
CUSIP:  15117K-10-3
Value:  1,290,911
Shrs or Prn Amt:
Ssh Prnamt:  668866
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  464958
Shared:  0
None:  203908
Info Table:
Name of Issuer:  Cellectis ADR
Title of Class:  SPONS ADS
CUSIP:  15117K-10-3
Value:  964,160
Shrs or Prn Amt:
Ssh Prnamt:  499565
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  499565
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cellectis ADR
Title of Class:  SPONS ADS
CUSIP:  15117K-10-3
Value:  180,509
Shrs or Prn Amt:
Ssh Prnamt:  93528
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  76659
Shared:  0
None:  16869
Info Table:
Name of Issuer:  Cellectis ADR
Title of Class:  SPONS ADS
CUSIP:  15117K-10-3
Value:  729,418
Shrs or Prn Amt:
Ssh Prnamt:  377937
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  377937
Shared:  0
None:  0
Info Table:
Name of Issuer:  Celsius Holdings
Title of Class:  COM
CUSIP:  15118V-20-7
Value:  28,997
Shrs or Prn Amt:
Ssh Prnamt:  312
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  312
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cemex ADR
Title of Class:  SPON ADR NEW
CUSIP:  151290-88-9
Value:  248,625,681
Shrs or Prn Amt:
Ssh Prnamt:  44959436
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  11795100
Shared:  0
None:  33164336
Info Table:
Name of Issuer:  Cemex ADR
Title of Class:  SPON ADR NEW
CUSIP:  151290-88-9
Value:  63,234,167
Shrs or Prn Amt:
Ssh Prnamt:  11434750
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  11434750
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cemex ADR
Title of Class:  SPON ADR NEW
CUSIP:  151290-88-9
Value:  97,343,152
Shrs or Prn Amt:
Ssh Prnamt:  17602740
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1732114
Shared:  0
None:  15870626
Info Table:
Name of Issuer:  Cemex ADR
Title of Class:  SPON ADR NEW
CUSIP:  151290-88-9
Value:  4,361,953
Shrs or Prn Amt:
Ssh Prnamt:  788780
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  788780
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cemex ADR
Title of Class:  SPON ADR NEW
CUSIP:  151290-88-9
Value:  4,384,831
Shrs or Prn Amt:
Ssh Prnamt:  792917
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  792917
Shared:  0
None:  0
Info Table:
Name of Issuer:  Certara
Title of Class:  COM
CUSIP:  15687V-10-9
Value:  27,627,818
Shrs or Prn Amt:
Ssh Prnamt:  1145907
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1145907
Shared:  0
None:  0
Info Table:
Name of Issuer:  Certara
Title of Class:  COM
CUSIP:  15687V-10-9
Value:  80,674,013
Shrs or Prn Amt:
Ssh Prnamt:  3346081
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2952572
Shared:  0
None:  393509
Info Table:
Name of Issuer:  Certara
Title of Class:  COM
CUSIP:  15687V-10-9
Value:  98,470,834
Shrs or Prn Amt:
Ssh Prnamt:  4084232
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2632508
Shared:  0
None:  1451724
Info Table:
Name of Issuer:  Certara
Title of Class:  COM
CUSIP:  15687V-10-9
Value:  22,244,513
Shrs or Prn Amt:
Ssh Prnamt:  922626
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  509337
Shared:  0
None:  413289
Info Table:
Name of Issuer:  Cerus
Title of Class:  COM
CUSIP:  157085-10-1
Value:  4,333
Shrs or Prn Amt:
Ssh Prnamt:  1459
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1459
Shared:  0
None:  0
Info Table:
Name of Issuer:  ChargePoint Holdings Inc
Title of Class:  COM CL A
CUSIP:  15961R-10-5
Value:  60,183,036
Shrs or Prn Amt:
Ssh Prnamt:  5748141
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5748141
Shared:  0
None:  0
Info Table:
Name of Issuer:  ChargePoint Holdings Inc
Title of Class:  COM CL A
CUSIP:  15961R-10-5
Value:  80,818
Shrs or Prn Amt:
Ssh Prnamt:  7719
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  7719
Shared:  0
None:  0
Info Table:
Name of Issuer:  Charles River Laboratories International
Title of Class:  COM
CUSIP:  159864-10-7
Value:  30,273
Shrs or Prn Amt:
Ssh Prnamt:  150
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  150
Shared:  0
None:  0
Info Table:
Name of Issuer:  Charles River Laboratories International
Title of Class:  COM
CUSIP:  159864-10-7
Value:  11,717,467
Shrs or Prn Amt:
Ssh Prnamt:  58059
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  58059
Shared:  0
None:  0
Info Table:
Name of Issuer:  Charles River Laboratories International
Title of Class:  COM
CUSIP:  159864-10-7
Value:  5,505,851
Shrs or Prn Amt:
Ssh Prnamt:  27281
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  27281
Shared:  0
None:  0
Info Table:
Name of Issuer:  Charles Schwab
Title of Class:  COM
CUSIP:  808513-10-5
Value:  47,783,760
Shrs or Prn Amt:
Ssh Prnamt:  912252
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  912252
Shared:  0
None:  0
Info Table:
Name of Issuer:  Charles Schwab
Title of Class:  COM
CUSIP:  808513-10-5
Value:  143,624,546
Shrs or Prn Amt:
Ssh Prnamt:  2741973
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2426674
Shared:  0
None:  315299
Info Table:
Name of Issuer:  Charles Schwab
Title of Class:  COM
CUSIP:  808513-10-5
Value:  37,370,144
Shrs or Prn Amt:
Ssh Prnamt:  713443
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  392239
Shared:  0
None:  321204
Info Table:
Name of Issuer:  Charles Schwab
Title of Class:  COM
CUSIP:  808513-10-5
Value:  169,458,467
Shrs or Prn Amt:
Ssh Prnamt:  3235175
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2114813
Shared:  0
None:  1120362
Info Table:
Name of Issuer:  Chegg
Title of Class:  COM
CUSIP:  163092-10-9
Value:  82,863,740
Shrs or Prn Amt:
Ssh Prnamt:  5083665
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  5083665
Shared:  0
None:  0
Info Table:
Name of Issuer:  Chegg
Title of Class:  COM
CUSIP:  163092-10-9
Value:  99,620,400
Shrs or Prn Amt:
Ssh Prnamt:  6111681
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  5304914
Shared:  0
None:  806767
Info Table:
Name of Issuer:  Chegg
Title of Class:  COM
CUSIP:  163092-10-9
Value:  25,416,427
Shrs or Prn Amt:
Ssh Prnamt:  1559290
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1559290
Shared:  0
None:  0
Info Table:
Name of Issuer:  Chegg
Title of Class:  COM
CUSIP:  163092-10-9
Value:  11,491,924
Shrs or Prn Amt:
Ssh Prnamt:  705026
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  645802
Shared:  0
None:  59224
Info Table:
Name of Issuer:  Chewy Inc
Title of Class:  CL A
CUSIP:  16679L-10-9
Value:  146,158,043
Shrs or Prn Amt:
Ssh Prnamt:  3910060
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3910060
Shared:  0
None:  0
Info Table:
Name of Issuer:  Chewy Inc
Title of Class:  CL A
CUSIP:  16679L-10-9
Value:  278,619,867
Shrs or Prn Amt:
Ssh Prnamt:  7453715
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  7068764
Shared:  0
None:  384951
Info Table:
Name of Issuer:  Chewy Inc
Title of Class:  CL A
CUSIP:  16679L-10-9
Value:  36,052,150
Shrs or Prn Amt:
Ssh Prnamt:  964477
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  622569
Shared:  0
None:  341908
Info Table:
Name of Issuer:  Chewy Inc
Title of Class:  CL A
CUSIP:  16679L-10-9
Value:  157,011,924
Shrs or Prn Amt:
Ssh Prnamt:  4200426
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2929751
Shared:  0
None:  1270675
Info Table:
Name of Issuer:  Chinook Therapeutics
Title of Class:  COM
CUSIP:  16961L-10-6
Value:  2,136,166
Shrs or Prn Amt:
Ssh Prnamt:  92275
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  92275
Shared:  0
None:  0
Info Table:
Name of Issuer:  Chinook Therapeutics
Title of Class:  COM
CUSIP:  16961L-10-6
Value:  4,724,475
Shrs or Prn Amt:
Ssh Prnamt:  204081
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  60146
Shared:  0
None:  143935
Info Table:
Name of Issuer:  Chinook Therapeutics
Title of Class:  COM
CUSIP:  16961L-10-6
Value:  2,709,893
Shrs or Prn Amt:
Ssh Prnamt:  117058
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  117058
Shared:  0
None:  0
Info Table:
Name of Issuer:  Chinook Therapeutics
Title of Class:  COM
CUSIP:  16961L-10-6
Value:  1,694,140
Shrs or Prn Amt:
Ssh Prnamt:  73181
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  73181
Shared:  0
None:  0
Info Table:
Name of Issuer:  Church & Dwight Co Inc
Title of Class:  COM
CUSIP:  171340-10-2
Value:  19,892
Shrs or Prn Amt:
Ssh Prnamt:  225
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  225
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cisco Systems
Title of Class:  COM
CUSIP:  17275R-10-2
Value:  30,010,084
Shrs or Prn Amt:
Ssh Prnamt:  574081
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  574081
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cisco Systems
Title of Class:  COM
CUSIP:  17275R-10-2
Value:  17,597,542
Shrs or Prn Amt:
Ssh Prnamt:  336634
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  336634
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cisco Systems
Title of Class:  COM
CUSIP:  17275R-10-2
Value:  6,374,152
Shrs or Prn Amt:
Ssh Prnamt:  121935
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  121935
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cisco Systems
Title of Class:  COM
CUSIP:  17275R-10-2
Value:  280,351
Shrs or Prn Amt:
Ssh Prnamt:  5363
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  5363
Info Table:
Name of Issuer:  Clear Secure Inc
Title of Class:  COM
CUSIP:  18467V-10-9
Value:  26,170,000
Shrs or Prn Amt:
Ssh Prnamt:  1000000
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1000000
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cloudflare Inc
Title of Class:  CL A COM
CUSIP:  18915M-10-7
Value:  398,495,200
Shrs or Prn Amt:
Ssh Prnamt:  6462783
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  4435317
Shared:  0
None:  2027466
Info Table:
Name of Issuer:  Cloudflare Inc
Title of Class:  CL A COM
CUSIP:  18915M-10-7
Value:  123,932,037
Shrs or Prn Amt:
Ssh Prnamt:  2009926
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1628423
Shared:  0
None:  381503
Info Table:
Name of Issuer:  Cloudflare Inc
Title of Class:  CL A COM
CUSIP:  18915M-10-7
Value:  238,818,552
Shrs or Prn Amt:
Ssh Prnamt:  3873152
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3873152
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cloudflare Inc
Title of Class:  CL A COM
CUSIP:  18915M-10-7
Value:  824,509,628
Shrs or Prn Amt:
Ssh Prnamt:  13371872
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  8387118
Shared:  0
None:  4984754
Info Table:
Name of Issuer:  CoStar Group
Title of Class:  COM
CUSIP:  22160N-10-9
Value:  218,201,967
Shrs or Prn Amt:
Ssh Prnamt:  3169237
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3169237
Shared:  0
None:  0
Info Table:
Name of Issuer:  CoStar Group
Title of Class:  COM
CUSIP:  22160N-10-9
Value:  401,843,369
Shrs or Prn Amt:
Ssh Prnamt:  5836505
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  5596802
Shared:  0
None:  239703
Info Table:
Name of Issuer:  CoStar Group
Title of Class:  COM
CUSIP:  22160N-10-9
Value:  43,087,363
Shrs or Prn Amt:
Ssh Prnamt:  625815
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  416866
Shared:  0
None:  208949
Info Table:
Name of Issuer:  CoStar Group
Title of Class:  COM
CUSIP:  22160N-10-9
Value:  186,543,429
Shrs or Prn Amt:
Ssh Prnamt:  2709418
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1968812
Shared:  0
None:  740606
Info Table:
Name of Issuer:  Coca Cola
Title of Class:  COM
CUSIP:  191216-10-0
Value:  18,861,400
Shrs or Prn Amt:
Ssh Prnamt:  304069
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  304069
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coca Cola
Title of Class:  COM
CUSIP:  191216-10-0
Value:  462,868
Shrs or Prn Amt:
Ssh Prnamt:  7462
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  7462
Info Table:
Name of Issuer:  Coca Cola
Title of Class:  COM
CUSIP:  191216-10-0
Value:  955,200
Shrs or Prn Amt:
Ssh Prnamt:  15399
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  15399
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coca Cola
Title of Class:  COM
CUSIP:  191216-10-0
Value:  29,147,029
Shrs or Prn Amt:
Ssh Prnamt:  469886
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  469886
Shared:  0
None:  0
Info Table:
Name of Issuer:  Codexis
Title of Class:  COM
CUSIP:  192005-10-6
Value:  8,719,896
Shrs or Prn Amt:
Ssh Prnamt:  2106255
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2106255
Shared:  0
None:  0
Info Table:
Name of Issuer:  Codexis
Title of Class:  COM
CUSIP:  192005-10-6
Value:  6,644,563
Shrs or Prn Amt:
Ssh Prnamt:  1604967
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1604967
Shared:  0
None:  0
Info Table:
Name of Issuer:  Codexis
Title of Class:  COM
CUSIP:  192005-10-6
Value:  2,791,648
Shrs or Prn Amt:
Ssh Prnamt:  674311
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  674311
Shared:  0
None:  0
Info Table:
Name of Issuer:  Codexis
Title of Class:  COM
CUSIP:  192005-10-6
Value:  7,128,608
Shrs or Prn Amt:
Ssh Prnamt:  1721886
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  495066
Shared:  0
None:  1226820
Info Table:
Name of Issuer:  Cognex Corp
Title of Class:  COM
CUSIP:  192422-10-3
Value:  29,294,208
Shrs or Prn Amt:
Ssh Prnamt:  591205
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  591205
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cognex Corp
Title of Class:  COM
CUSIP:  192422-10-3
Value:  13,018,470
Shrs or Prn Amt:
Ssh Prnamt:  262734
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  262734
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cognex Corp
Title of Class:  COM
CUSIP:  192422-10-3
Value:  6,864,607
Shrs or Prn Amt:
Ssh Prnamt:  138539
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  122639
Shared:  0
None:  15900
Info Table:
Name of Issuer:  Cognex Corp
Title of Class:  COM
CUSIP:  192422-10-3
Value:  4,004,730
Shrs or Prn Amt:
Ssh Prnamt:  80822
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  29829
Shared:  0
None:  50993
Info Table:
Name of Issuer:  Cognizant Technology Solutions Corp
Title of Class:  CL A
CUSIP:  192446-10-2
Value:  13,039
Shrs or Prn Amt:
Ssh Prnamt:  214
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  214
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cognyte Software
Title of Class:  ORD SHS
CUSIP:  M25133-10-5
Value:  1,251
Shrs or Prn Amt:
Ssh Prnamt:  369
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  369
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coherent Corp
Title of Class:  COM
CUSIP:  19247G-10-7
Value:  19,649
Shrs or Prn Amt:
Ssh Prnamt:  516
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  516
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coherus BioSciences
Title of Class:  COM
CUSIP:  19249H-10-3
Value:  10,841
Shrs or Prn Amt:
Ssh Prnamt:  1585
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1585
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cohu
Title of Class:  COM
CUSIP:  192576-10-6
Value:  30,251
Shrs or Prn Amt:
Ssh Prnamt:  788
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  788
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coinbase Global Inc
Title of Class:  COM CL A
CUSIP:  19260Q-10-7
Value:  862,734
Shrs or Prn Amt:
Ssh Prnamt:  12768
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  12768
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coinbase Global Inc
Title of Class:  COM CL A
CUSIP:  19260Q-10-7
Value:  3,176
Shrs or Prn Amt:
Ssh Prnamt:  47
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  47
Shared:  0
None:  0
Info Table:
Name of Issuer:  Consensus Cloud Solutions
Title of Class:  COM
CUSIP:  20848V-10-5
Value:  818
Shrs or Prn Amt:
Ssh Prnamt:  24
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  24
Shared:  0
None:  0
Info Table:
Name of Issuer:  Consolidated Edison
Title of Class:  COM
CUSIP:  209115-10-4
Value:  866,101
Shrs or Prn Amt:
Ssh Prnamt:  9053
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  9053
Shared:  0
None:  0
Info Table:
Name of Issuer:  Consolidated Edison
Title of Class:  COM
CUSIP:  209115-10-4
Value:  11,135,127
Shrs or Prn Amt:
Ssh Prnamt:  116391
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  116391
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cooper Cos Inc/The
Title of Class:  COM
CUSIP:  216648-40-2
Value:  11,167,198
Shrs or Prn Amt:
Ssh Prnamt:  29910
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  29910
Shared:  0
None:  0
Info Table:
Name of Issuer:  Copa Holdings S A
Title of Class:  CL A
CUSIP:  P31076-10-5
Value:  64,481,263
Shrs or Prn Amt:
Ssh Prnamt:  698227
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  74166
Shared:  0
None:  624061
Info Table:
Name of Issuer:  Copa Holdings S A
Title of Class:  CL A
CUSIP:  P31076-10-5
Value:  3,050,598
Shrs or Prn Amt:
Ssh Prnamt:  33033
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  33033
Shared:  0
None:  0
Info Table:
Name of Issuer:  Copa Holdings S A
Title of Class:  CL A
CUSIP:  P31076-10-5
Value:  28,652,049
Shrs or Prn Amt:
Ssh Prnamt:  310255
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  310255
Shared:  0
None:  0
Info Table:
Name of Issuer:  Copa Holdings S A
Title of Class:  CL A
CUSIP:  P31076-10-5
Value:  275,319,269
Shrs or Prn Amt:
Ssh Prnamt:  2981259
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1977298
Shared:  0
None:  1003961
Info Table:
Name of Issuer:  Corning
Title of Class:  COM
CUSIP:  219350-10-5
Value:  25,790
Shrs or Prn Amt:
Ssh Prnamt:  731
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  731
Shared:  0
None:  0
Info Table:
Name of Issuer:  Costco Wholesale Corporation
Title of Class:  COM
CUSIP:  22160K-10-5
Value:  38,756
Shrs or Prn Amt:
Ssh Prnamt:  78
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  78
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coupang
Title of Class:  CL A
CUSIP:  22266T-10-9
Value:  1,083,904
Shrs or Prn Amt:
Ssh Prnamt:  67744
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  67744
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coupang
Title of Class:  CL A
CUSIP:  22266T-10-9
Value:  258,221,552
Shrs or Prn Amt:
Ssh Prnamt:  16138847
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  8580431
Shared:  0
None:  7558416
Info Table:
Name of Issuer:  Coupang
Title of Class:  CL A
CUSIP:  22266T-10-9
Value:  141,190,000
Shrs or Prn Amt:
Ssh Prnamt:  8824375
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  5727980
Shared:  0
None:  3096395
Info Table:
Name of Issuer:  Coupang
Title of Class:  CL A
CUSIP:  22266T-10-9
Value:  1,265,597,600
Shrs or Prn Amt:
Ssh Prnamt:  79099850
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  52126552
Shared:  0
None:  26973298
Info Table:
Name of Issuer:  Coupang
Title of Class:  CL A
CUSIP:  22266T-10-9
Value:  127,113,536
Shrs or Prn Amt:
Ssh Prnamt:  7944596
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  7944596
Shared:  0
None:  0
Info Table:
Name of Issuer:  Coursera Inc
Title of Class:  COM
CUSIP:  22266M-10-4
Value:  22,839,875
Shrs or Prn Amt:
Ssh Prnamt:  1982628
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1454291
Shared:  0
None:  528337
Info Table:
Name of Issuer:  Coursera Inc
Title of Class:  COM
CUSIP:  22266M-10-4
Value:  32,416,980
Shrs or Prn Amt:
Ssh Prnamt:  2813974
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2268903
Shared:  0
None:  545071
Info Table:
Name of Issuer:  Coursera Inc
Title of Class:  COM
CUSIP:  22266M-10-4
Value:  86,889,600
Shrs or Prn Amt:
Ssh Prnamt:  7542500
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6864384
Shared:  0
None:  678116
Info Table:
Name of Issuer:  Coursera Inc
Title of Class:  COM
CUSIP:  22266M-10-4
Value:  73,767,249
Shrs or Prn Amt:
Ssh Prnamt:  6403407
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  6403407
Shared:  0
None:  0
Info Table:
Name of Issuer:  Credicorp
Title of Class:  COM
CUSIP:  G2519Y-10-8
Value:  37,560,764
Shrs or Prn Amt:
Ssh Prnamt:  283713
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  32802
Shared:  0
None:  250911
Info Table:
Name of Issuer:  Credicorp
Title of Class:  COM
CUSIP:  G2519Y-10-8
Value:  1,908,799
Shrs or Prn Amt:
Ssh Prnamt:  14418
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  14418
Shared:  0
None:  0
Info Table:
Name of Issuer:  Credicorp
Title of Class:  COM
CUSIP:  G2519Y-10-8
Value:  124,798,757
Shrs or Prn Amt:
Ssh Prnamt:  942660
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  417061
Shared:  0
None:  525599
Info Table:
Name of Issuer:  Credicorp
Title of Class:  COM
CUSIP:  G2519Y-10-8
Value:  20,562,285
Shrs or Prn Amt:
Ssh Prnamt:  155316
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  155316
Shared:  0
None:  0
Info Table:
Name of Issuer:  Crispr Therapeutics AG
Title of Class:  REG SHS
CUSIP:  H17182-10-8
Value:  3,373,615
Shrs or Prn Amt:
Ssh Prnamt:  74588
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  74588
Shared:  0
None:  0
Info Table:
Name of Issuer:  Crispr Therapeutics AG
Title of Class:  REG SHS
CUSIP:  H17182-10-8
Value:  581,748
Shrs or Prn Amt:
Ssh Prnamt:  12862
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  8803
Shared:  0
None:  4059
Info Table:
Name of Issuer:  Crispr Therapeutics AG
Title of Class:  REG SHS
CUSIP:  H17182-10-8
Value:  401,642
Shrs or Prn Amt:
Ssh Prnamt:  8880
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  8880
Shared:  0
None:  0
Info Table:
Name of Issuer:  Crispr Therapeutics AG
Title of Class:  REG SHS
CUSIP:  H17182-10-8
Value:  7,554,360
Shrs or Prn Amt:
Ssh Prnamt:  167021
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  167021
Shared:  0
None:  0
Info Table:
Name of Issuer:  CrowdStrike Holdings
Title of Class:  COM
CUSIP:  22788C-10-5
Value:  15,648
Shrs or Prn Amt:
Ssh Prnamt:  114
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  114
Shared:  0
None:  0
Info Table:
Name of Issuer:  CyberArk Software Ltd
Title of Class:  SHS
CUSIP:  M2682V-10-8
Value:  8,525,424
Shrs or Prn Amt:
Ssh Prnamt:  57612
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  57612
Shared:  0
None:  0
Info Table:
Name of Issuer:  CyberArk Software Ltd
Title of Class:  SHS
CUSIP:  M2682V-10-8
Value:  6,461,547
Shrs or Prn Amt:
Ssh Prnamt:  43665
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  43665
Shared:  0
None:  0
Info Table:
Name of Issuer:  CyberArk Software Ltd
Title of Class:  SHS
CUSIP:  M2682V-10-8
Value:  15,386,960
Shrs or Prn Amt:
Ssh Prnamt:  103980
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  30224
Shared:  0
None:  73756
Info Table:
Name of Issuer:  CyberArk Software Ltd
Title of Class:  SHS
CUSIP:  M2682V-10-8
Value:  5,996,594
Shrs or Prn Amt:
Ssh Prnamt:  40523
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  40523
Shared:  0
None:  0
Info Table:
Name of Issuer:  Cytokinetics Inc
Title of Class:  COM NEW
CUSIP:  23282W-60-5
Value:  11,965
Shrs or Prn Amt:
Ssh Prnamt:  340
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  340
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dada Nexus Ltd ADR
Title of Class:  ADS
CUSIP:  23344D-10-8
Value:  27,889,271
Shrs or Prn Amt:
Ssh Prnamt:  3292712
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  3292712
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dada Nexus Ltd ADR
Title of Class:  ADS
CUSIP:  23344D-10-8
Value:  311,840
Shrs or Prn Amt:
Ssh Prnamt:  36817
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  36817
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dada Nexus Ltd ADR
Title of Class:  ADS
CUSIP:  23344D-10-8
Value:  20,012,213
Shrs or Prn Amt:
Ssh Prnamt:  2362717
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2362717
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dada Nexus Ltd ADR
Title of Class:  ADS
CUSIP:  23344D-10-8
Value:  11,916,392
Shrs or Prn Amt:
Ssh Prnamt:  1406894
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1406894
Shared:  0
None:  0
Info Table:
Name of Issuer:  Datadog
Title of Class:  COM
CUSIP:  23804L-10-3
Value:  111,099,174
Shrs or Prn Amt:
Ssh Prnamt:  1529028
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1529028
Shared:  0
None:  0
Info Table:
Name of Issuer:  Datadog
Title of Class:  COM
CUSIP:  23804L-10-3
Value:  206,647,002
Shrs or Prn Amt:
Ssh Prnamt:  2844027
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2717410
Shared:  0
None:  126617
Info Table:
Name of Issuer:  Datadog
Title of Class:  COM
CUSIP:  23804L-10-3
Value:  24,459,245
Shrs or Prn Amt:
Ssh Prnamt:  336626
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  220007
Shared:  0
None:  116619
Info Table:
Name of Issuer:  Datadog
Title of Class:  COM
CUSIP:  23804L-10-3
Value:  100,642,892
Shrs or Prn Amt:
Ssh Prnamt:  1385121
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  985110
Shared:  0
None:  400011
Info Table:
Name of Issuer:  Deere & Co
Title of Class:  COM
CUSIP:  244199-10-5
Value:  111,168,766
Shrs or Prn Amt:
Ssh Prnamt:  269252
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  178643
Shared:  0
None:  90609
Info Table:
Name of Issuer:  Deere & Co
Title of Class:  COM
CUSIP:  244199-10-5
Value:  154,865,508
Shrs or Prn Amt:
Ssh Prnamt:  375086
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  375086
Shared:  0
None:  0
Info Table:
Name of Issuer:  Deere & Co
Title of Class:  COM
CUSIP:  244199-10-5
Value:  156,144,610
Shrs or Prn Amt:
Ssh Prnamt:  378184
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  299097
Shared:  0
None:  79087
Info Table:
Name of Issuer:  Deere & Co
Title of Class:  COM
CUSIP:  244199-10-5
Value:  50,439,485
Shrs or Prn Amt:
Ssh Prnamt:  122165
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  48378
Shared:  0
None:  73787
Info Table:
Name of Issuer:  Denali Therapeutics
Title of Class:  COM
CUSIP:  24823R-10-5
Value:  71,034,209
Shrs or Prn Amt:
Ssh Prnamt:  3083082
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3083082
Shared:  0
None:  0
Info Table:
Name of Issuer:  Denali Therapeutics
Title of Class:  COM
CUSIP:  24823R-10-5
Value:  107,037,827
Shrs or Prn Amt:
Ssh Prnamt:  4645739
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4505448
Shared:  0
None:  140291
Info Table:
Name of Issuer:  Denali Therapeutics
Title of Class:  COM
CUSIP:  24823R-10-5
Value:  9,921,738
Shrs or Prn Amt:
Ssh Prnamt:  430631
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  397365
Shared:  0
None:  33266
Info Table:
Name of Issuer:  Denali Therapeutics
Title of Class:  COM
CUSIP:  24823R-10-5
Value:  165,718,863
Shrs or Prn Amt:
Ssh Prnamt:  7192659
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  7192659
Shared:  0
None:  0
Info Table:
Name of Issuer:  DermTech
Title of Class:  COM
CUSIP:  24984K-10-5
Value:  1,052
Shrs or Prn Amt:
Ssh Prnamt:  286
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  286
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dexcom Inc
Title of Class:  COM
CUSIP:  252131-10-7
Value:  257,056,034
Shrs or Prn Amt:
Ssh Prnamt:  2212567
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2212567
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dexcom Inc
Title of Class:  COM
CUSIP:  252131-10-7
Value:  1,042,993,983
Shrs or Prn Amt:
Ssh Prnamt:  8977397
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  3918712
Shared:  0
None:  5058685
Info Table:
Name of Issuer:  Dexcom Inc
Title of Class:  COM
CUSIP:  252131-10-7
Value:  345,987,874
Shrs or Prn Amt:
Ssh Prnamt:  2978033
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2494469
Shared:  0
None:  483564
Info Table:
Name of Issuer:  Dexcom Inc
Title of Class:  COM
CUSIP:  252131-10-7
Value:  347,320,342
Shrs or Prn Amt:
Ssh Prnamt:  2989502
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1279053
Shared:  0
None:  1710449
Info Table:
Name of Issuer:  Digimarc
Title of Class:  COM
CUSIP:  25381B-10-1
Value:  2,333,241
Shrs or Prn Amt:
Ssh Prnamt:  118740
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  118740
Shared:  0
None:  0
Info Table:
Name of Issuer:  Digimarc
Title of Class:  COM
CUSIP:  25381B-10-1
Value:  5,514,301
Shrs or Prn Amt:
Ssh Prnamt:  280626
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  85774
Shared:  0
None:  194852
Info Table:
Name of Issuer:  Digimarc
Title of Class:  COM
CUSIP:  25381B-10-1
Value:  5,157,044
Shrs or Prn Amt:
Ssh Prnamt:  262445
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  262445
Shared:  0
None:  0
Info Table:
Name of Issuer:  Digimarc
Title of Class:  COM
CUSIP:  25381B-10-1
Value:  3,040,071
Shrs or Prn Amt:
Ssh Prnamt:  154711
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  154711
Shared:  0
None:  0
Info Table:
Name of Issuer:  Digital Realty Trust REIT
Title of Class:  COM
CUSIP:  253868-10-3
Value:  450,456
Shrs or Prn Amt:
Ssh Prnamt:  4582
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  4582
Shared:  0
None:  0
Info Table:
Name of Issuer:  Docebo
Title of Class:  COM
CUSIP:  25609L-10-5
Value:  8,256,720
Shrs or Prn Amt:
Ssh Prnamt:  203094
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  178313
Shared:  0
None:  24781
Info Table:
Name of Issuer:  Docebo
Title of Class:  COM
CUSIP:  25609L-10-5
Value:  10,855
Shrs or Prn Amt:
Ssh Prnamt:  267
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  267
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dolby Laboratories 'A'
Title of Class:  COM
CUSIP:  25659T-10-7
Value:  22,179,986
Shrs or Prn Amt:
Ssh Prnamt:  259658
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  259658
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dolby Laboratories 'A'
Title of Class:  COM
CUSIP:  25659T-10-7
Value:  10,237,587
Shrs or Prn Amt:
Ssh Prnamt:  119850
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  117505
Shared:  0
None:  2345
Info Table:
Name of Issuer:  Dolby Laboratories 'A'
Title of Class:  COM
CUSIP:  25659T-10-7
Value:  21,562,400
Shrs or Prn Amt:
Ssh Prnamt:  252428
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  252428
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dolby Laboratories 'A'
Title of Class:  COM
CUSIP:  25659T-10-7
Value:  4,565,528
Shrs or Prn Amt:
Ssh Prnamt:  53448
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  53448
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dollar General Corp
Title of Class:  COM
CUSIP:  256677-10-5
Value:  15,153
Shrs or Prn Amt:
Ssh Prnamt:  72
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  72
Shared:  0
None:  0
Info Table:
Name of Issuer:  Domo
Title of Class:  COM
CUSIP:  257554-10-5
Value:  4,555
Shrs or Prn Amt:
Ssh Prnamt:  321
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  321
Shared:  0
None:  0
Info Table:
Name of Issuer:  Donaldson
Title of Class:  COM
CUSIP:  257651-10-9
Value:  31,886
Shrs or Prn Amt:
Ssh Prnamt:  488
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  488
Shared:  0
None:  0
Info Table:
Name of Issuer:  Doordash Inc
Title of Class:  COM
CUSIP:  25809K-10-5
Value:  146,373,595
Shrs or Prn Amt:
Ssh Prnamt:  2302920
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2302920
Shared:  0
None:  0
Info Table:
Name of Issuer:  Doordash Inc
Title of Class:  COM
CUSIP:  25809K-10-5
Value:  265,603,320
Shrs or Prn Amt:
Ssh Prnamt:  4178781
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4013816
Shared:  0
None:  164965
Info Table:
Name of Issuer:  Doordash Inc
Title of Class:  COM
CUSIP:  25809K-10-5
Value:  178,054,823
Shrs or Prn Amt:
Ssh Prnamt:  2801366
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2307553
Shared:  0
None:  493813
Info Table:
Name of Issuer:  Doordash Inc
Title of Class:  COM
CUSIP:  25809K-10-5
Value:  28,191,212
Shrs or Prn Amt:
Ssh Prnamt:  443537
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  299058
Shared:  0
None:  144479
Info Table:
Name of Issuer:  Doximity Inc
Title of Class:  CLASS A
CUSIP:  26622P-10-7
Value:  48,065,746
Shrs or Prn Amt:
Ssh Prnamt:  1484427
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1484427
Shared:  0
None:  0
Info Table:
Name of Issuer:  Doximity Inc
Title of Class:  CLASS A
CUSIP:  26622P-10-7
Value:  62,446,546
Shrs or Prn Amt:
Ssh Prnamt:  1928553
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1911910
Shared:  0
None:  16643
Info Table:
Name of Issuer:  Doximity Inc
Title of Class:  CLASS A
CUSIP:  26622P-10-7
Value:  10,158,869
Shrs or Prn Amt:
Ssh Prnamt:  313739
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  313739
Shared:  0
None:  0
Info Table:
Name of Issuer:  Doximity Inc
Title of Class:  CLASS A
CUSIP:  26622P-10-7
Value:  21,435,754
Shrs or Prn Amt:
Ssh Prnamt:  662006
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  662006
Shared:  0
None:  0
Info Table:
Name of Issuer:  DraftKings Inc
Title of Class:  COM CL A
CUSIP:  26142V-10-5
Value:  27,685
Shrs or Prn Amt:
Ssh Prnamt:  1430
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1430
Shared:  0
None:  0
Info Table:
Name of Issuer:  Dropbox
Title of Class:  CL A
CUSIP:  26210C-10-4
Value:  21,815
Shrs or Prn Amt:
Ssh Prnamt:  1009
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1009
Shared:  0
None:  0
Info Table:
Name of Issuer:  Duolingo Inc
Title of Class:  CL A COM
CUSIP:  26603R-10-6
Value:  224,529,344
Shrs or Prn Amt:
Ssh Prnamt:  1574650
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1574650
Shared:  0
None:  0
Info Table:
Name of Issuer:  Duolingo Inc
Title of Class:  CL A COM
CUSIP:  26603R-10-6
Value:  82,900,685
Shrs or Prn Amt:
Ssh Prnamt:  581392
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  472611
Shared:  0
None:  108781
Info Table:
Name of Issuer:  Duolingo Inc
Title of Class:  CL A COM
CUSIP:  26603R-10-6
Value:  276,094,593
Shrs or Prn Amt:
Ssh Prnamt:  1936283
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1797112
Shared:  0
None:  139171
Info Table:
Name of Issuer:  Duolingo Inc
Title of Class:  CL A COM
CUSIP:  26603R-10-6
Value:  53,513,884
Shrs or Prn Amt:
Ssh Prnamt:  375299
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  270030
Shared:  0
None:  105269
Info Table:
Name of Issuer:  EHang Holdings Ltd ADR
Title of Class:  ADS
CUSIP:  26853E-10-2
Value:  36,222
Shrs or Prn Amt:
Ssh Prnamt:  3314
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3314
Shared:  0
None:  0
Info Table:
Name of Issuer:  Eargo Inc
Title of Class:  COM
CUSIP:  270087-10-9
Value:  61
Shrs or Prn Amt:
Ssh Prnamt:  13
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  13
Shared:  0
None:  0
Info Table:
Name of Issuer:  Eaton
Title of Class:  COM
CUSIP:  G29183-10-3
Value:  120,432,659
Shrs or Prn Amt:
Ssh Prnamt:  702887
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  619536
Shared:  0
None:  83351
Info Table:
Name of Issuer:  Eaton
Title of Class:  COM
CUSIP:  G29183-10-3
Value:  40,996,864
Shrs or Prn Amt:
Ssh Prnamt:  239272
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  239272
Shared:  0
None:  0
Info Table:
Name of Issuer:  Eaton
Title of Class:  COM
CUSIP:  G29183-10-3
Value:  32,677,451
Shrs or Prn Amt:
Ssh Prnamt:  190717
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  105065
Shared:  0
None:  85652
Info Table:
Name of Issuer:  Eaton
Title of Class:  COM
CUSIP:  G29183-10-3
Value:  145,253,656
Shrs or Prn Amt:
Ssh Prnamt:  847751
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  543021
Shared:  0
None:  304730
Info Table:
Name of Issuer:  Ecolab
Title of Class:  COM
CUSIP:  278865-10-0
Value:  69,126,983
Shrs or Prn Amt:
Ssh Prnamt:  417610
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  417610
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ecolab
Title of Class:  COM
CUSIP:  278865-10-0
Value:  50,871,673
Shrs or Prn Amt:
Ssh Prnamt:  307326
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  207043
Shared:  0
None:  100283
Info Table:
Name of Issuer:  Ecolab
Title of Class:  COM
CUSIP:  278865-10-0
Value:  67,215,608
Shrs or Prn Amt:
Ssh Prnamt:  406063
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  317738
Shared:  0
None:  88325
Info Table:
Name of Issuer:  Ecolab
Title of Class:  COM
CUSIP:  278865-10-0
Value:  19,774,048
Shrs or Prn Amt:
Ssh Prnamt:  119459
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  33860
Shared:  0
None:  85599
Info Table:
Name of Issuer:  Edwards Lifesciences Corp
Title of Class:  COM
CUSIP:  28176E-10-8
Value:  9,395,977
Shrs or Prn Amt:
Ssh Prnamt:  113574
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  113574
Shared:  0
None:  0
Info Table:
Name of Issuer:  Edwards Lifesciences Corp
Title of Class:  COM
CUSIP:  28176E-10-8
Value:  19,701,901
Shrs or Prn Amt:
Ssh Prnamt:  238147
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  238147
Shared:  0
None:  0
Info Table:
Name of Issuer:  Edwards Lifesciences Corp
Title of Class:  COM
CUSIP:  28176E-10-8
Value:  3,796,314
Shrs or Prn Amt:
Ssh Prnamt:  45888
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  45888
Shared:  0
None:  0
Info Table:
Name of Issuer:  Edwards Lifesciences Corp
Title of Class:  COM
CUSIP:  28176E-10-8
Value:  5,780,759
Shrs or Prn Amt:
Ssh Prnamt:  69875
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  69875
Shared:  0
None:  0
Info Table:
Name of Issuer:  Elastic
Title of Class:  ORD SHS
CUSIP:  N14506-10-4
Value:  442,015,143
Shrs or Prn Amt:
Ssh Prnamt:  7634113
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6652597
Shared:  0
None:  981516
Info Table:
Name of Issuer:  Electronic Arts, Inc.
Title of Class:  COM
CUSIP:  285512-10-9
Value:  24,933
Shrs or Prn Amt:
Ssh Prnamt:  207
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  207
Shared:  0
None:  0
Info Table:
Name of Issuer:  Elevance Health Inc
Title of Class:  COM
CUSIP:  036752-10-3
Value:  174,131,426
Shrs or Prn Amt:
Ssh Prnamt:  378703
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  378703
Shared:  0
None:  0
Info Table:
Name of Issuer:  Elevance Health Inc
Title of Class:  COM
CUSIP:  036752-10-3
Value:  536,692,531
Shrs or Prn Amt:
Ssh Prnamt:  1167205
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1035363
Shared:  0
None:  131842
Info Table:
Name of Issuer:  Elevance Health Inc
Title of Class:  COM
CUSIP:  036752-10-3
Value:  138,240,497
Shrs or Prn Amt:
Ssh Prnamt:  300647
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  165681
Shared:  0
None:  134966
Info Table:
Name of Issuer:  Elevance Health Inc
Title of Class:  COM
CUSIP:  036752-10-3
Value:  621,413,903
Shrs or Prn Amt:
Ssh Prnamt:  1351458
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  870338
Shared:  0
None:  481120
Info Table:
Name of Issuer:  Enanta Pharmaceuticals
Title of Class:  COM
CUSIP:  29251M-10-6
Value:  14,558
Shrs or Prn Amt:
Ssh Prnamt:  360
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  360
Shared:  0
None:  0
Info Table:
Name of Issuer:  Enphase Energy Inc
Title of Class:  COM
CUSIP:  29355A-10-7
Value:  201,448
Shrs or Prn Amt:
Ssh Prnamt:  958
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  958
Shared:  0
None:  0
Info Table:
Name of Issuer:  Enphase Energy Inc
Title of Class:  COM
CUSIP:  29355A-10-7
Value:  21,659
Shrs or Prn Amt:
Ssh Prnamt:  103
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  103
Shared:  0
None:  0
Info Table:
Name of Issuer:  Entegris Inc
Title of Class:  COM
CUSIP:  29362U-10-4
Value:  26,817,844
Shrs or Prn Amt:
Ssh Prnamt:  327007
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  327007
Shared:  0
None:  0
Info Table:
Name of Issuer:  Entegris Inc
Title of Class:  COM
CUSIP:  29362U-10-4
Value:  76,793,836
Shrs or Prn Amt:
Ssh Prnamt:  936396
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  826215
Shared:  0
None:  110181
Info Table:
Name of Issuer:  Entegris Inc
Title of Class:  COM
CUSIP:  29362U-10-4
Value:  20,613,624
Shrs or Prn Amt:
Ssh Prnamt:  251355
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  135982
Shared:  0
None:  115373
Info Table:
Name of Issuer:  Entegris Inc
Title of Class:  COM
CUSIP:  29362U-10-4
Value:  93,748,337
Shrs or Prn Amt:
Ssh Prnamt:  1143133
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  728186
Shared:  0
None:  414947
Info Table:
Name of Issuer:  Estee Lauder 'A'
Title of Class:  COM
CUSIP:  518439-10-4
Value:  66,247,709
Shrs or Prn Amt:
Ssh Prnamt:  268797
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  268797
Shared:  0
None:  0
Info Table:
Name of Issuer:  Estee Lauder 'A'
Title of Class:  COM
CUSIP:  518439-10-4
Value:  219,715,886
Shrs or Prn Amt:
Ssh Prnamt:  891487
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  797257
Shared:  0
None:  94230
Info Table:
Name of Issuer:  Estee Lauder 'A'
Title of Class:  COM
CUSIP:  518439-10-4
Value:  247,186,564
Shrs or Prn Amt:
Ssh Prnamt:  1002948
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  656802
Shared:  0
None:  346146
Info Table:
Name of Issuer:  Estee Lauder 'A'
Title of Class:  COM
CUSIP:  518439-10-4
Value:  53,177,935
Shrs or Prn Amt:
Ssh Prnamt:  215767
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  118792
Shared:  0
None:  96975
Info Table:
Name of Issuer:  EverQuote Inc
Title of Class:  COM CL A
CUSIP:  30041R-10-8
Value:  2,073,616
Shrs or Prn Amt:
Ssh Prnamt:  149181
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  149181
Shared:  0
None:  0
Info Table:
Name of Issuer:  EverQuote Inc
Title of Class:  COM CL A
CUSIP:  30041R-10-8
Value:  3,596,500
Shrs or Prn Amt:
Ssh Prnamt:  258741
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  77422
Shared:  0
None:  181319
Info Table:
Name of Issuer:  EverQuote Inc
Title of Class:  COM CL A
CUSIP:  30041R-10-8
Value:  9,993,641
Shrs or Prn Amt:
Ssh Prnamt:  718967
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  718967
Shared:  0
None:  0
Info Table:
Name of Issuer:  EverQuote Inc
Title of Class:  COM CL A
CUSIP:  30041R-10-8
Value:  3,218,545
Shrs or Prn Amt:
Ssh Prnamt:  231550
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  231550
Shared:  0
None:  0
Info Table:
Name of Issuer:  Everbridge Inc
Title of Class:  COM
CUSIP:  29978A-10-4
Value:  6,956,848
Shrs or Prn Amt:
Ssh Prnamt:  200659
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  200659
Shared:  0
None:  0
Info Table:
Name of Issuer:  Everbridge Inc
Title of Class:  COM
CUSIP:  29978A-10-4
Value:  5,146,623
Shrs or Prn Amt:
Ssh Prnamt:  148446
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  148446
Shared:  0
None:  0
Info Table:
Name of Issuer:  Everbridge Inc
Title of Class:  COM
CUSIP:  29978A-10-4
Value:  6,796,256
Shrs or Prn Amt:
Ssh Prnamt:  196027
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  57778
Shared:  0
None:  138249
Info Table:
Name of Issuer:  Everbridge Inc
Title of Class:  COM
CUSIP:  29978A-10-4
Value:  2,893,905
Shrs or Prn Amt:
Ssh Prnamt:  83470
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  83470
Shared:  0
None:  0
Info Table:
Name of Issuer:  Eversource Energy
Title of Class:  COM
CUSIP:  30040W-10-8
Value:  11,244,397
Shrs or Prn Amt:
Ssh Prnamt:  143680
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  143680
Shared:  0
None:  0
Info Table:
Name of Issuer:  Eversource Energy
Title of Class:  COM
CUSIP:  30040W-10-8
Value:  657,932
Shrs or Prn Amt:
Ssh Prnamt:  8407
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  8407
Shared:  0
None:  0
Info Table:
Name of Issuer:  Exact Sciences
Title of Class:  COM
CUSIP:  30063P-10-5
Value:  42,240,205
Shrs or Prn Amt:
Ssh Prnamt:  622920
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  509014
Shared:  0
None:  113906
Info Table:
Name of Issuer:  Exact Sciences
Title of Class:  COM
CUSIP:  30063P-10-5
Value:  103,865,526
Shrs or Prn Amt:
Ssh Prnamt:  1531714
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  962439
Shared:  0
None:  569275
Info Table:
Name of Issuer:  Exact Sciences
Title of Class:  COM
CUSIP:  30063P-10-5
Value:  73,348,178
Shrs or Prn Amt:
Ssh Prnamt:  1081672
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1081672
Shared:  0
None:  0
Info Table:
Name of Issuer:  Exact Sciences
Title of Class:  COM
CUSIP:  30063P-10-5
Value:  104,836,972
Shrs or Prn Amt:
Ssh Prnamt:  1546040
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1160982
Shared:  0
None:  385058
Info Table:
Name of Issuer:  Exelixis
Title of Class:  COM
CUSIP:  30161Q-10-4
Value:  27,077
Shrs or Prn Amt:
Ssh Prnamt:  1395
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1395
Shared:  0
None:  0
Info Table:
Name of Issuer:  Exelon Corporation
Title of Class:  COM
CUSIP:  30161N-10-1
Value:  957,647
Shrs or Prn Amt:
Ssh Prnamt:  22861
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  22861
Shared:  0
None:  0
Info Table:
Name of Issuer:  Expedia Group Inc
Title of Class:  COM
CUSIP:  30212P-30-3
Value:  19,309
Shrs or Prn Amt:
Ssh Prnamt:  199
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  199
Shared:  0
None:  0
Info Table:
Name of Issuer:  Expeditors Intl
Title of Class:  COM
CUSIP:  302130-10-9
Value:  13,765
Shrs or Prn Amt:
Ssh Prnamt:  125
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  125
Shared:  0
None:  0
Info Table:
Name of Issuer:  Expensify Inc
Title of Class:  COM CL A
CUSIP:  30219Q-10-6
Value:  22,551
Shrs or Prn Amt:
Ssh Prnamt:  2767
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2767
Shared:  0
None:  0
Info Table:
Name of Issuer:  Expensify Inc
Title of Class:  COM CL A
CUSIP:  30219Q-10-6
Value:  5,681,854
Shrs or Prn Amt:
Ssh Prnamt:  697160
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  697160
Shared:  0
None:  0
Info Table:
Name of Issuer:  Expensify Inc
Title of Class:  COM CL A
CUSIP:  30219Q-10-6
Value:  316,424
Shrs or Prn Amt:
Ssh Prnamt:  38825
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  38825
Shared:  0
None:  0
Info Table:
Name of Issuer:  Expensify Inc
Title of Class:  COM CL A
CUSIP:  30219Q-10-6
Value:  2,927,024
Shrs or Prn Amt:
Ssh Prnamt:  359144
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  359144
Shared:  0
None:  0
Info Table:
Name of Issuer:  Exponent
Title of Class:  COM
CUSIP:  30214U-10-2
Value:  26,418
Shrs or Prn Amt:
Ssh Prnamt:  265
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  265
Shared:  0
None:  0
Info Table:
Name of Issuer:  Exscientia Ltd ADR
Title of Class:  ADS
CUSIP:  30223G-10-2
Value:  5,908,573
Shrs or Prn Amt:
Ssh Prnamt:  1114825
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1114825
Shared:  0
None:  0
Info Table:
Name of Issuer:  Exscientia Ltd ADR
Title of Class:  ADS
CUSIP:  30223G-10-2
Value:  1,993,065
Shrs or Prn Amt:
Ssh Prnamt:  376050
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  376050
Shared:  0
None:  0
Info Table:
Name of Issuer:  Exscientia Ltd ADR
Title of Class:  ADS
CUSIP:  30223G-10-2
Value:  10,793,567
Shrs or Prn Amt:
Ssh Prnamt:  2036522
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  389701
Shared:  0
None:  1646821
Info Table:
Name of Issuer:  Exscientia Ltd ADR
Title of Class:  ADS
CUSIP:  30223G-10-2
Value:  9,087,820
Shrs or Prn Amt:
Ssh Prnamt:  1714683
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  930650
Shared:  0
None:  784033
Info Table:
Name of Issuer:  FTI Consulting
Title of Class:  COM
CUSIP:  302941-10-9
Value:  36,510
Shrs or Prn Amt:
Ssh Prnamt:  185
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  185
Shared:  0
None:  0
Info Table:
Name of Issuer:  FTI Consulting
Title of Class:  COM
CUSIP:  302941-10-9
Value:  10,092,084
Shrs or Prn Amt:
Ssh Prnamt:  51138
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  51138
Shared:  0
None:  0
Info Table:
Name of Issuer:  Factset Research Systems
Title of Class:  COM
CUSIP:  303075-10-5
Value:  33,207
Shrs or Prn Amt:
Ssh Prnamt:  80
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  80
Shared:  0
None:  0
Info Table:
Name of Issuer:  Farfetch
Title of Class:  ORD SHS CL A
CUSIP:  30744W-10-7
Value:  25,379,662
Shrs or Prn Amt:
Ssh Prnamt:  5168974
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  5168974
Shared:  0
None:  0
Info Table:
Name of Issuer:  Farfetch
Title of Class:  ORD SHS CL A
CUSIP:  30744W-10-7
Value:  103,956,955
Shrs or Prn Amt:
Ssh Prnamt:  21172496
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  15501723
Shared:  0
None:  5670773
Info Table:
Name of Issuer:  Farfetch
Title of Class:  ORD SHS CL A
CUSIP:  30744W-10-7
Value:  13,441,449
Shrs or Prn Amt:
Ssh Prnamt:  2737566
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1642049
Shared:  0
None:  1095517
Info Table:
Name of Issuer:  Farfetch
Title of Class:  ORD SHS CL A
CUSIP:  30744W-10-7
Value:  76,684,429
Shrs or Prn Amt:
Ssh Prnamt:  15618010
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  9679229
Shared:  0
None:  5938781
Info Table:
Name of Issuer:  Fastenal
Title of Class:  COM
CUSIP:  311900-10-4
Value:  79,727,527
Shrs or Prn Amt:
Ssh Prnamt:  1478078
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1478078
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fastenal
Title of Class:  COM
CUSIP:  311900-10-4
Value:  49,012,149
Shrs or Prn Amt:
Ssh Prnamt:  908642
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  908642
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fastenal
Title of Class:  COM
CUSIP:  311900-10-4
Value:  17,971,729
Shrs or Prn Amt:
Ssh Prnamt:  333180
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  318181
Shared:  0
None:  14999
Info Table:
Name of Issuer:  Fastenal
Title of Class:  COM
CUSIP:  311900-10-4
Value:  15,549,176
Shrs or Prn Amt:
Ssh Prnamt:  288268
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  229031
Shared:  0
None:  59237
Info Table:
Name of Issuer:  Fastly
Title of Class:  CL A
CUSIP:  31188V-10-0
Value:  3,641
Shrs or Prn Amt:
Ssh Prnamt:  205
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  205
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fate Therapeutics
Title of Class:  COM
CUSIP:  31189P-10-2
Value:  2,120
Shrs or Prn Amt:
Ssh Prnamt:  372
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  372
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ferrari NV
Title of Class:  COM
CUSIP:  N3167Y-10-3
Value:  368,325,761
Shrs or Prn Amt:
Ssh Prnamt:  1359921
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1359921
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ferrari NV
Title of Class:  COM
CUSIP:  N3167Y-10-3
Value:  1,624,781,193
Shrs or Prn Amt:
Ssh Prnamt:  5998779
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4641594
Shared:  0
None:  1357185
Info Table:
Name of Issuer:  Fibrogen Inc
Title of Class:  COM
CUSIP:  31572Q-80-8
Value:  10,058
Shrs or Prn Amt:
Ssh Prnamt:  539
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  539
Shared:  0
None:  0
Info Table:
Name of Issuer:  First Industrial REIT
Title of Class:  COM
CUSIP:  32054K-10-3
Value:  21,644,739
Shrs or Prn Amt:
Ssh Prnamt:  406856
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  406856
Shared:  0
None:  0
Info Table:
Name of Issuer:  First Industrial REIT
Title of Class:  COM
CUSIP:  32054K-10-3
Value:  2,218,227
Shrs or Prn Amt:
Ssh Prnamt:  41696
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  41696
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fiverr Intl
Title of Class:  ORD SHS
CUSIP:  M4R82T-10-6
Value:  4,174,162
Shrs or Prn Amt:
Ssh Prnamt:  119535
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  119535
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fiverr Intl
Title of Class:  ORD SHS
CUSIP:  M4R82T-10-6
Value:  10,188,329
Shrs or Prn Amt:
Ssh Prnamt:  291762
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  86109
Shared:  0
None:  205653
Info Table:
Name of Issuer:  Fiverr Intl
Title of Class:  ORD SHS
CUSIP:  M4R82T-10-6
Value:  12,001,410
Shrs or Prn Amt:
Ssh Prnamt:  343683
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  343683
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fiverr Intl
Title of Class:  ORD SHS
CUSIP:  M4R82T-10-6
Value:  11,295,782
Shrs or Prn Amt:
Ssh Prnamt:  323476
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  323476
Shared:  0
None:  0
Info Table:
Name of Issuer:  Floor & Decor Holdings
Title of Class:  CL A
CUSIP:  339750-10-1
Value:  24,043,176
Shrs or Prn Amt:
Ssh Prnamt:  244789
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  135485
Shared:  0
None:  109304
Info Table:
Name of Issuer:  Floor & Decor Holdings
Title of Class:  CL A
CUSIP:  339750-10-1
Value:  88,820,150
Shrs or Prn Amt:
Ssh Prnamt:  904298
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  799016
Shared:  0
None:  105282
Info Table:
Name of Issuer:  Floor & Decor Holdings
Title of Class:  CL A
CUSIP:  339750-10-1
Value:  30,010,532
Shrs or Prn Amt:
Ssh Prnamt:  305544
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  305544
Shared:  0
None:  0
Info Table:
Name of Issuer:  Floor & Decor Holdings
Title of Class:  CL A
CUSIP:  339750-10-1
Value:  110,990,073
Shrs or Prn Amt:
Ssh Prnamt:  1130015
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  739969
Shared:  0
None:  390046
Info Table:
Name of Issuer:  Fortis
Title of Class:  COM
CUSIP:  349553-10-7
Value:  1,015,282
Shrs or Prn Amt:
Ssh Prnamt:  23917
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  23917
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fortive Corp
Title of Class:  COM
CUSIP:  34959J-10-8
Value:  6,667,980
Shrs or Prn Amt:
Ssh Prnamt:  97814
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  97814
Shared:  0
None:  0
Info Table:
Name of Issuer:  Fox
Title of Class:  COM
CUSIP:  35137L-10-5
Value:  16,344
Shrs or Prn Amt:
Ssh Prnamt:  480
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  480
Shared:  0
None:  0
Info Table:
Name of Issuer:  Freshpet Inc
Title of Class:  COM
CUSIP:  358039-10-5
Value:  35,941
Shrs or Prn Amt:
Ssh Prnamt:  543
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  543
Shared:  0
None:  0
Info Table:
Name of Issuer:  Freshpet Inc
Title of Class:  COM
CUSIP:  358039-10-5
Value:  505,890
Shrs or Prn Amt:
Ssh Prnamt:  7643
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  7643
Shared:  0
None:  0
Info Table:
Name of Issuer:  Full Truck Alliance Co Ltd ADR
Title of Class:  SPONS ADS
CUSIP:  35969L-10-8
Value:  120,403,586
Shrs or Prn Amt:
Ssh Prnamt:  15821759
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  15396396
Shared:  0
None:  425363
Info Table:
Name of Issuer:  Futu Hdgs ADR
Title of Class:  SPON ADR CL A
CUSIP:  36118L-10-6
Value:  56,049,176
Shrs or Prn Amt:
Ssh Prnamt:  1080987
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  823109
Shared:  0
None:  257878
Info Table:
Name of Issuer:  Futu Hdgs ADR
Title of Class:  SPON ADR CL A
CUSIP:  36118L-10-6
Value:  1,607
Shrs or Prn Amt:
Ssh Prnamt:  31
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  31
Shared:  0
None:  0
Info Table:
Name of Issuer:  GAN
Title of Class:  COM
CUSIP:  G3728V-10-9
Value:  738
Shrs or Prn Amt:
Ssh Prnamt:  572
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  572
Shared:  0
None:  0
Info Table:
Name of Issuer:  Gentex Corp
Title of Class:  COM
CUSIP:  371901-10-9
Value:  16,341
Shrs or Prn Amt:
Ssh Prnamt:  583
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  583
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ginkgo Bioworks Holdings Inc
Title of Class:  CL A COM
CUSIP:  37611X-10-0
Value:  29,056,525
Shrs or Prn Amt:
Ssh Prnamt:  21847011
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  21847011
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ginkgo Bioworks Holdings Inc
Title of Class:  CL A COM
CUSIP:  37611X-10-0
Value:  115,432,655
Shrs or Prn Amt:
Ssh Prnamt:  86791470
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  48395045
Shared:  0
None:  38396425
Info Table:
Name of Issuer:  Ginkgo Bioworks Holdings Inc
Title of Class:  CL A COM
CUSIP:  37611X-10-0
Value:  17,531,473
Shrs or Prn Amt:
Ssh Prnamt:  13181559
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  11422564
Shared:  0
None:  1758995
Info Table:
Name of Issuer:  Ginkgo Bioworks Holdings Inc
Title of Class:  CL A COM
CUSIP:  37611X-10-0
Value:  160,994,133
Shrs or Prn Amt:
Ssh Prnamt:  121048220
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  109728005
Shared:  0
None:  11320215
Info Table:
Name of Issuer:  GitLab
Title of Class:  CLASS A
CUSIP:  37637K-10-8
Value:  14,127
Shrs or Prn Amt:
Ssh Prnamt:  412
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  412
Shared:  0
None:  0
Info Table:
Name of Issuer:  GitLab
Title of Class:  CLASS A
CUSIP:  37637K-10-8
Value:  3,874,496
Shrs or Prn Amt:
Ssh Prnamt:  112992
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  112992
Shared:  0
None:  0
Info Table:
Name of Issuer:  Globus Medical
Title of Class:  CL A
CUSIP:  379577-20-8
Value:  22,939
Shrs or Prn Amt:
Ssh Prnamt:  405
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  405
Shared:  0
None:  0
Info Table:
Name of Issuer:  Globus Medical
Title of Class:  CL A
CUSIP:  379577-20-8
Value:  6,212,898
Shrs or Prn Amt:
Ssh Prnamt:  109691
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  109691
Shared:  0
None:  0
Info Table:
Name of Issuer:  Golub Capital BDC Inc
Title of Class:  COM
CUSIP:  38173M-10-2
Value:  1,655,676
Shrs or Prn Amt:
Ssh Prnamt:  122100
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  122100
Shared:  0
None:  0
Info Table:
Name of Issuer:  Goodyear Tire & Rubber Co/The
Title of Class:  COM
CUSIP:  382550-10-1
Value:  18,800
Shrs or Prn Amt:
Ssh Prnamt:  1706
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1706
Shared:  0
None:  0
Info Table:
Name of Issuer:  Graco
Title of Class:  COM
CUSIP:  384109-10-4
Value:  29,277
Shrs or Prn Amt:
Ssh Prnamt:  401
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  401
Shared:  0
None:  0
Info Table:
Name of Issuer:  Grainger, WW
Title of Class:  COM
CUSIP:  384802-10-4
Value:  46,839
Shrs or Prn Amt:
Ssh Prnamt:  68
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  68
Shared:  0
None:  0
Info Table:
Name of Issuer:  HDFC Bank ADR
Title of Class:  ADR REPS 3 SHS
CUSIP:  40415F-10-1
Value:  97,325,866
Shrs or Prn Amt:
Ssh Prnamt:  1459815
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1265571
Shared:  0
None:  194244
Info Table:
Name of Issuer:  HDFC Bank ADR
Title of Class:  ADR REPS 3 SHS
CUSIP:  40415F-10-1
Value:  11,433,505
Shrs or Prn Amt:
Ssh Prnamt:  171494
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  113811
Shared:  0
None:  57683
Info Table:
Name of Issuer:  HDFC Bank ADR
Title of Class:  ADR REPS 3 SHS
CUSIP:  40415F-10-1
Value:  117,984,366
Shrs or Prn Amt:
Ssh Prnamt:  1769677
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1082203
Shared:  0
None:  687474
Info Table:
Name of Issuer:  HUYA ADR
Title of Class:  ADS REP SHS A
CUSIP:  44852D-10-8
Value:  4,131,898
Shrs or Prn Amt:
Ssh Prnamt:  1144570
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1144570
Shared:  0
None:  0
Info Table:
Name of Issuer:  HUYA ADR
Title of Class:  ADS REP SHS A
CUSIP:  44852D-10-8
Value:  2,242,319
Shrs or Prn Amt:
Ssh Prnamt:  621141
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  621141
Shared:  0
None:  0
Info Table:
Name of Issuer:  Harris Corp
Title of Class:  COM
CUSIP:  502431-10-9
Value:  11,971
Shrs or Prn Amt:
Ssh Prnamt:  61
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  61
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hashicorp Inc
Title of Class:  COM CL A
CUSIP:  418100-10-3
Value:  77,268,660
Shrs or Prn Amt:
Ssh Prnamt:  2638056
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2638056
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hashicorp Inc
Title of Class:  COM CL A
CUSIP:  418100-10-3
Value:  110,800,438
Shrs or Prn Amt:
Ssh Prnamt:  3782876
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  3515608
Shared:  0
None:  267268
Info Table:
Name of Issuer:  Hashicorp Inc
Title of Class:  COM CL A
CUSIP:  418100-10-3
Value:  8,263,588
Shrs or Prn Amt:
Ssh Prnamt:  282130
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  282130
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hashicorp Inc
Title of Class:  COM CL A
CUSIP:  418100-10-3
Value:  16,916,820
Shrs or Prn Amt:
Ssh Prnamt:  577563
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  577563
Shared:  0
None:  0
Info Table:
Name of Issuer:  Health Catalyst Inc
Title of Class:  COM
CUSIP:  42225T-10-7
Value:  2,783,867
Shrs or Prn Amt:
Ssh Prnamt:  238549
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  238549
Shared:  0
None:  0
Info Table:
Name of Issuer:  Health Catalyst Inc
Title of Class:  COM
CUSIP:  42225T-10-7
Value:  3,023,043
Shrs or Prn Amt:
Ssh Prnamt:  259044
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  259044
Shared:  0
None:  0
Info Table:
Name of Issuer:  Health Catalyst Inc
Title of Class:  COM
CUSIP:  42225T-10-7
Value:  1,215,664
Shrs or Prn Amt:
Ssh Prnamt:  104170
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  104170
Shared:  0
None:  0
Info Table:
Name of Issuer:  Healthcare Realty Trust REIT
Title of Class:  CL A COM
CUSIP:  42226K-10-5
Value:  298,977
Shrs or Prn Amt:
Ssh Prnamt:  15467
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  15467
Shared:  0
None:  0
Info Table:
Name of Issuer:  Healthcare Services Group Inc
Title of Class:  COM
CUSIP:  421906-10-8
Value:  2,178
Shrs or Prn Amt:
Ssh Prnamt:  157
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  157
Shared:  0
None:  0
Info Table:
Name of Issuer:  Heron Therapeutics Inc
Title of Class:  COM
CUSIP:  427746-10-2
Value:  465
Shrs or Prn Amt:
Ssh Prnamt:  308
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  308
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hershey Foods Corporation
Title of Class:  COM
CUSIP:  427866-10-8
Value:  6,879,755
Shrs or Prn Amt:
Ssh Prnamt:  27042
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  27042
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hershey Foods Corporation
Title of Class:  COM
CUSIP:  427866-10-8
Value:  25,187
Shrs or Prn Amt:
Ssh Prnamt:  99
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  99
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hershey Foods Corporation
Title of Class:  COM
CUSIP:  427866-10-8
Value:  19,291,910
Shrs or Prn Amt:
Ssh Prnamt:  75830
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  75830
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hillenbrand
Title of Class:  COM
CUSIP:  431571-10-8
Value:  8,080
Shrs or Prn Amt:
Ssh Prnamt:  170
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  170
Shared:  0
None:  0
Info Table:
Name of Issuer:  Howard Hughes
Title of Class:  COM
CUSIP:  44267D-10-7
Value:  26,120,480
Shrs or Prn Amt:
Ssh Prnamt:  326506
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  326506
Shared:  0
None:  0
Info Table:
Name of Issuer:  Howard Hughes
Title of Class:  COM
CUSIP:  44267D-10-7
Value:  74,783,440
Shrs or Prn Amt:
Ssh Prnamt:  934793
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  827351
Shared:  0
None:  107442
Info Table:
Name of Issuer:  Howard Hughes
Title of Class:  COM
CUSIP:  44267D-10-7
Value:  20,245,280
Shrs or Prn Amt:
Ssh Prnamt:  253066
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  142291
Shared:  0
None:  110775
Info Table:
Name of Issuer:  Howard Hughes
Title of Class:  COM
CUSIP:  44267D-10-7
Value:  89,645,440
Shrs or Prn Amt:
Ssh Prnamt:  1120568
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  708054
Shared:  0
None:  412514
Info Table:
Name of Issuer:  Humana
Title of Class:  COM
CUSIP:  444859-10-2
Value:  31,069
Shrs or Prn Amt:
Ssh Prnamt:  64
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  64
Shared:  0
None:  0
Info Table:
Name of Issuer:  Hutchison China Meditech
Title of Class:  SPONSORED ADR
CUSIP:  44842L-10-3
Value:  1,981,970
Shrs or Prn Amt:
Ssh Prnamt:  152225
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  0
Shared:  0
None:  152225
Info Table:
Name of Issuer:  ICICI Bank ADR
Title of Class:  ADR
CUSIP:  45104G-10-4
Value:  58,129,636
Shrs or Prn Amt:
Ssh Prnamt:  2693681
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2693681
Shared:  0
None:  0
Info Table:
Name of Issuer:  ICICI Bank ADR
Title of Class:  ADR
CUSIP:  45104G-10-4
Value:  58,787,826
Shrs or Prn Amt:
Ssh Prnamt:  2724181
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2724181
Shared:  0
None:  0
Info Table:
Name of Issuer:  ICICI Bank ADR
Title of Class:  ADR
CUSIP:  45104G-10-4
Value:  10,549,491
Shrs or Prn Amt:
Ssh Prnamt:  488855
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  329682
Shared:  0
None:  159173
Info Table:
Name of Issuer:  ICICI Bank ADR
Title of Class:  ADR
CUSIP:  45104G-10-4
Value:  2,397,689
Shrs or Prn Amt:
Ssh Prnamt:  111107
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  111107
Shared:  0
None:  0
Info Table:
Name of Issuer:  IPG Photonics Corp
Title of Class:  COM
CUSIP:  44980X-10-9
Value:  11,139,332
Shrs or Prn Amt:
Ssh Prnamt:  90336
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  90336
Shared:  0
None:  0
Info Table:
Name of Issuer:  IPG Photonics Corp
Title of Class:  COM
CUSIP:  44980X-10-9
Value:  5,562,267
Shrs or Prn Amt:
Ssh Prnamt:  45108
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  45108
Shared:  0
None:  0
Info Table:
Name of Issuer:  IPG Photonics Corp
Title of Class:  COM
CUSIP:  44980X-10-9
Value:  14,889,313
Shrs or Prn Amt:
Ssh Prnamt:  120747
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  120747
Shared:  0
None:  0
Info Table:
Name of Issuer:  IPG Photonics Corp
Title of Class:  COM
CUSIP:  44980X-10-9
Value:  13,425,623
Shrs or Prn Amt:
Ssh Prnamt:  108877
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  31590
Shared:  0
None:  77287
Info Table:
Name of Issuer:  Illumina
Title of Class:  COM
CUSIP:  452327-10-9
Value:  2,029,342,226
Shrs or Prn Amt:
Ssh Prnamt:  8726477
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6453547
Shared:  0
None:  2272930
Info Table:
Name of Issuer:  Illumina
Title of Class:  COM
CUSIP:  452327-10-9
Value:  306,052,078
Shrs or Prn Amt:
Ssh Prnamt:  1316070
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1053085
Shared:  0
None:  262985
Info Table:
Name of Issuer:  Illumina
Title of Class:  COM
CUSIP:  452327-10-9
Value:  358,722,328
Shrs or Prn Amt:
Ssh Prnamt:  1542560
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1542560
Shared:  0
None:  0
Info Table:
Name of Issuer:  Illumina
Title of Class:  COM
CUSIP:  452327-10-9
Value:  811,192,770
Shrs or Prn Amt:
Ssh Prnamt:  3488251
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2588351
Shared:  0
None:  899900
Info Table:
Name of Issuer:  InMode
Title of Class:  SHS
CUSIP:  M5425M-10-3
Value:  21,062
Shrs or Prn Amt:
Ssh Prnamt:  659
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  659
Shared:  0
None:  0
Info Table:
Name of Issuer:  Incyte Corp
Title of Class:  COM
CUSIP:  45337C-10-2
Value:  11,925
Shrs or Prn Amt:
Ssh Prnamt:  165
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  165
Shared:  0
None:  0
Info Table:
Name of Issuer:  Infinera
Title of Class:  COM
CUSIP:  45667G-10-3
Value:  24,832
Shrs or Prn Amt:
Ssh Prnamt:  3200
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  3200
Shared:  0
None:  0
Info Table:
Name of Issuer:  Infosys Ltd ADR
Title of Class:  SPONSORED ADR
CUSIP:  456788-10-8
Value:  2,978,543
Shrs or Prn Amt:
Ssh Prnamt:  170788
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  170788
Shared:  0
None:  0
Info Table:
Name of Issuer:  Infosys Ltd ADR
Title of Class:  SPONSORED ADR
CUSIP:  456788-10-8
Value:  14,919,920
Shrs or Prn Amt:
Ssh Prnamt:  855500
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  114422
Shared:  0
None:  741078
Info Table:
Name of Issuer:  Infosys Ltd ADR
Title of Class:  SPONSORED ADR
CUSIP:  456788-10-8
Value:  16,307,917
Shrs or Prn Amt:
Ssh Prnamt:  935087
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  935087
Shared:  0
None:  0
Info Table:
Name of Issuer:  Infosys Ltd ADR
Title of Class:  SPONSORED ADR
CUSIP:  456788-10-8
Value:  20,561,673
Shrs or Prn Amt:
Ssh Prnamt:  1178995
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  470491
Shared:  0
None:  708504
Info Table:
Name of Issuer:  Insmed Inc
Title of Class:  COM
CUSIP:  457669-30-7
Value:  13,674
Shrs or Prn Amt:
Ssh Prnamt:  802
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  802
Shared:  0
None:  0
Info Table:
Name of Issuer:  Inspire Medical Systems
Title of Class:  COM
CUSIP:  457730-10-9
Value:  43,303
Shrs or Prn Amt:
Ssh Prnamt:  185
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  185
Shared:  0
None:  0
Info Table:
Name of Issuer:  Intercept Pharmaceuticals Inc
Title of Class:  COM
CUSIP:  45845P-10-8
Value:  1,356
Shrs or Prn Amt:
Ssh Prnamt:  101
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  101
Shared:  0
None:  0
Info Table:
Name of Issuer:  International Game Technology
Title of Class:  SHS
CUSIP:  G4863A-10-8
Value:  34,063
Shrs or Prn Amt:
Ssh Prnamt:  1271
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1271
Shared:  0
None:  0
Info Table:
Name of Issuer:  Intuit
Title of Class:  COM
CUSIP:  461202-10-3
Value:  32,319,554
Shrs or Prn Amt:
Ssh Prnamt:  72493
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  72493
Shared:  0
None:  0
Info Table:
Name of Issuer:  Intuit
Title of Class:  COM
CUSIP:  461202-10-3
Value:  300,935
Shrs or Prn Amt:
Ssh Prnamt:  675
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  675
Info Table:
Name of Issuer:  Intuit
Title of Class:  COM
CUSIP:  461202-10-3
Value:  6,801,582
Shrs or Prn Amt:
Ssh Prnamt:  15256
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  15256
Shared:  0
None:  0
Info Table:
Name of Issuer:  Intuit
Title of Class:  COM
CUSIP:  461202-10-3
Value:  19,141,265
Shrs or Prn Amt:
Ssh Prnamt:  42934
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  42934
Shared:  0
None:  0
Info Table:
Name of Issuer:  Intuitive Surgical
Title of Class:  COM NEW
CUSIP:  46120E-60-2
Value:  658,504,837
Shrs or Prn Amt:
Ssh Prnamt:  2577621
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1064009
Shared:  0
None:  1513612
Info Table:
Name of Issuer:  Intuitive Surgical
Title of Class:  COM NEW
CUSIP:  46120E-60-2
Value:  75,527,662
Shrs or Prn Amt:
Ssh Prnamt:  295642
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  295642
Shared:  0
None:  0
Info Table:
Name of Issuer:  Intuitive Surgical
Title of Class:  COM NEW
CUSIP:  46120E-60-2
Value:  125,704,780
Shrs or Prn Amt:
Ssh Prnamt:  492053
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  423220
Shared:  0
None:  68833
Info Table:
Name of Issuer:  Intuitive Surgical
Title of Class:  COM NEW
CUSIP:  46120E-60-2
Value:  207,931,887
Shrs or Prn Amt:
Ssh Prnamt:  813919
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  352096
Shared:  0
None:  461823
Info Table:
Name of Issuer:  Invitae
Title of Class:  COM
CUSIP:  46185L-10-3
Value:  1,080
Shrs or Prn Amt:
Ssh Prnamt:  800
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  800
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ionis Pharmaceuticals
Title of Class:  COM
CUSIP:  462222-10-0
Value:  2,124,135
Shrs or Prn Amt:
Ssh Prnamt:  59433
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  59433
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ionis Pharmaceuticals
Title of Class:  COM
CUSIP:  462222-10-0
Value:  4,521,825
Shrs or Prn Amt:
Ssh Prnamt:  126520
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  126520
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ionis Pharmaceuticals
Title of Class:  COM
CUSIP:  462222-10-0
Value:  5,243,272
Shrs or Prn Amt:
Ssh Prnamt:  146706
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  146706
Shared:  0
None:  0
Info Table:
Name of Issuer:  Itau Unibanco Holding SA-ADR
Title of Class:  SPON ADR REP PFD
CUSIP:  465562-10-6
Value:  9,919,645
Shrs or Prn Amt:
Ssh Prnamt:  2036888
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2036888
Shared:  0
None:  0
Info Table:
Name of Issuer:  Itau Unibanco Holding SA-ADR
Title of Class:  SPON ADR REP PFD
CUSIP:  465562-10-6
Value:  33,293,531
Shrs or Prn Amt:
Ssh Prnamt:  6836454
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  453282
Shared:  0
None:  6383172
Info Table:
Name of Issuer:  Itau Unibanco Holding SA-ADR
Title of Class:  SPON ADR REP PFD
CUSIP:  465562-10-6
Value:  30,337,675
Shrs or Prn Amt:
Ssh Prnamt:  6229502
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  747989
Shared:  0
None:  5481513
Info Table:
Name of Issuer:  Itau Unibanco Holding SA-ADR
Title of Class:  SPON ADR REP PFD
CUSIP:  465562-10-6
Value:  1,828,446
Shrs or Prn Amt:
Ssh Prnamt:  375451
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  375451
Shared:  0
None:  0
Info Table:
Name of Issuer:  J&J Snack Foods Corp
Title of Class:  COM
CUSIP:  466032-10-9
Value:  15,267
Shrs or Prn Amt:
Ssh Prnamt:  103
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  103
Shared:  0
None:  0
Info Table:
Name of Issuer:  JFrog Ltd
Title of Class:  ORD SHS
CUSIP:  M6191J-10-0
Value:  11,917,298
Shrs or Prn Amt:
Ssh Prnamt:  604939
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  604939
Shared:  0
None:  0
Info Table:
Name of Issuer:  JFrog Ltd
Title of Class:  ORD SHS
CUSIP:  M6191J-10-0
Value:  9,866,784
Shrs or Prn Amt:
Ssh Prnamt:  500852
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  145045
Shared:  0
None:  355807
Info Table:
Name of Issuer:  JFrog Ltd
Title of Class:  ORD SHS
CUSIP:  M6191J-10-0
Value:  4,098,368
Shrs or Prn Amt:
Ssh Prnamt:  208039
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  208039
Shared:  0
None:  0
Info Table:
Name of Issuer:  JFrog Ltd
Title of Class:  ORD SHS
CUSIP:  M6191J-10-0
Value:  8,157,396
Shrs or Prn Amt:
Ssh Prnamt:  414081
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  414081
Shared:  0
None:  0
Info Table:
Name of Issuer:  Jack Henry & Associates
Title of Class:  COM
CUSIP:  426281-10-1
Value:  9,345
Shrs or Prn Amt:
Ssh Prnamt:  62
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  62
Shared:  0
None:  0
Info Table:
Name of Issuer:  Jazz Pharmaceuticals
Title of Class:  SHS
CUSIP:  G50871-10-5
Value:  28,242
Shrs or Prn Amt:
Ssh Prnamt:  193
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  193
Shared:  0
None:  0
Info Table:
Name of Issuer:  Joby Aviation Inc
Title of Class:  COM
CUSIP:  G65163-10-0
Value:  38,817
Shrs or Prn Amt:
Ssh Prnamt:  8944
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  8944
Shared:  0
None:  0
Info Table:
Name of Issuer:  Joby Aviation Inc
Title of Class:  COM
CUSIP:  G65163-10-0
Value:  33,319,048
Shrs or Prn Amt:
Ssh Prnamt:  7677200
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  7677200
Shared:  0
None:  0
Info Table:
Name of Issuer:  Johnson & Johnson
Title of Class:  COM
CUSIP:  478160-10-4
Value:  16,740
Shrs or Prn Amt:
Ssh Prnamt:  108
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  108
Shared:  0
None:  0
Info Table:
Name of Issuer:  Jumia Technologies Ag ADR
Title of Class:  SPONSORED ADS
CUSIP:  48138M-10-5
Value:  30,825,767
Shrs or Prn Amt:
Ssh Prnamt:  9369534
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  8697830
Shared:  0
None:  671704
Info Table:
Name of Issuer:  Jumia Technologies Ag ADR
Title of Class:  SPONSORED ADS
CUSIP:  48138M-10-5
Value:  1,230
Shrs or Prn Amt:
Ssh Prnamt:  374
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  374
Shared:  0
None:  0
Info Table:
Name of Issuer:  KE Holdings ADR
Title of Class:  ADR
CUSIP:  482497-10-4
Value:  8,228,238
Shrs or Prn Amt:
Ssh Prnamt:  436743
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  436743
Shared:  0
None:  0
Info Table:
Name of Issuer:  KE Holdings ADR
Title of Class:  ADR
CUSIP:  482497-10-4
Value:  19,991,124
Shrs or Prn Amt:
Ssh Prnamt:  1061100
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  628601
Shared:  0
None:  432499
Info Table:
Name of Issuer:  KE Holdings ADR
Title of Class:  ADR
CUSIP:  482497-10-4
Value:  1,081,284
Shrs or Prn Amt:
Ssh Prnamt:  57393
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  8210
Shared:  0
None:  49183
Info Table:
Name of Issuer:  KE Holdings ADR
Title of Class:  ADR
CUSIP:  482497-10-4
Value:  911,969
Shrs or Prn Amt:
Ssh Prnamt:  48406
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  48406
Shared:  0
None:  0
Info Table:
Name of Issuer:  KFORCE INC.
Title of Class:  COM
CUSIP:  493732-10-1
Value:  21,185
Shrs or Prn Amt:
Ssh Prnamt:  335
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  335
Shared:  0
None:  0
Info Table:
Name of Issuer:  Knowles Corp
Title of Class:  COM
CUSIP:  49926D-10-9
Value:  22,644
Shrs or Prn Amt:
Ssh Prnamt:  1332
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1332
Shared:  0
None:  0
Info Table:
Name of Issuer:  Kulicke & Soffa Industries Inc
Title of Class:  COM
CUSIP:  501242-10-1
Value:  28,295
Shrs or Prn Amt:
Ssh Prnamt:  537
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  537
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lemonade Inc
Title of Class:  COM
CUSIP:  52567D-10-7
Value:  35,717,764
Shrs or Prn Amt:
Ssh Prnamt:  2504752
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2480142
Shared:  0
None:  24610
Info Table:
Name of Issuer:  Lemonade Inc
Title of Class:  COM
CUSIP:  52567D-10-7
Value:  21,294,130
Shrs or Prn Amt:
Ssh Prnamt:  1493277
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1493277
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lemonade Inc
Title of Class:  COM
CUSIP:  52567D-10-7
Value:  1,386,557
Shrs or Prn Amt:
Ssh Prnamt:  97234
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  97234
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lemonade Inc
Title of Class:  COM
CUSIP:  52567D-10-7
Value:  13,521,646
Shrs or Prn Amt:
Ssh Prnamt:  948222
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  948222
Shared:  0
None:  0
Info Table:
Name of Issuer:  LendingTree
Title of Class:  COM
CUSIP:  52603B-10-7
Value:  4,952,761
Shrs or Prn Amt:
Ssh Prnamt:  185775
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  54367
Shared:  0
None:  131408
Info Table:
Name of Issuer:  LendingTree
Title of Class:  COM
CUSIP:  52603B-10-7
Value:  4,937,272
Shrs or Prn Amt:
Ssh Prnamt:  185194
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  185194
Shared:  0
None:  0
Info Table:
Name of Issuer:  LendingTree
Title of Class:  COM
CUSIP:  52603B-10-7
Value:  1,945,327
Shrs or Prn Amt:
Ssh Prnamt:  72968
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  72968
Shared:  0
None:  0
Info Table:
Name of Issuer:  LendingTree
Title of Class:  COM
CUSIP:  52603B-10-7
Value:  3,124,739
Shrs or Prn Amt:
Ssh Prnamt:  117207
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  117207
Shared:  0
None:  0
Info Table:
Name of Issuer:  Liberty Broadband Corp
Title of Class:  COM
CUSIP:  530307-30-5
Value:  9,232
Shrs or Prn Amt:
Ssh Prnamt:  113
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  113
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lightspeed POS
Title of Class:  COM
CUSIP:  53229C-10-7
Value:  4,707
Shrs or Prn Amt:
Ssh Prnamt:  310
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  310
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lilium N.V.
Title of Class:  CL A COM
CUSIP:  N52586-10-9
Value:  9,983
Shrs or Prn Amt:
Ssh Prnamt:  15359
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  15359
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lilium N.V.
Title of Class:  CL A COM
CUSIP:  N52586-10-9
Value:  727,300
Shrs or Prn Amt:
Ssh Prnamt:  1118923
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1118923
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lilium N.V.
Title of Class:  CL A COM
CUSIP:  N52586-10-9
Value:  9,863,327
Shrs or Prn Amt:
Ssh Prnamt:  15174349
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  15174349
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lincoln Electric Holdings Inc
Title of Class:  COM
CUSIP:  533900-10-6
Value:  17,417
Shrs or Prn Amt:
Ssh Prnamt:  103
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  103
Shared:  0
None:  0
Info Table:
Name of Issuer:  LivePerson Inc
Title of Class:  COM
CUSIP:  538146-10-1
Value:  1,296,941
Shrs or Prn Amt:
Ssh Prnamt:  294091
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  294091
Shared:  0
None:  0
Info Table:
Name of Issuer:  LivePerson Inc
Title of Class:  COM
CUSIP:  538146-10-1
Value:  1,093,151
Shrs or Prn Amt:
Ssh Prnamt:  247880
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  247880
Shared:  0
None:  0
Info Table:
Name of Issuer:  LivePerson Inc
Title of Class:  COM
CUSIP:  538146-10-1
Value:  546,540
Shrs or Prn Amt:
Ssh Prnamt:  123932
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  123932
Shared:  0
None:  0
Info Table:
Name of Issuer:  LivePerson Inc
Title of Class:  COM
CUSIP:  538146-10-1
Value:  1,586,224
Shrs or Prn Amt:
Ssh Prnamt:  359688
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  104853
Shared:  0
None:  254835
Info Table:
Name of Issuer:  Liveramp Holdings Inc
Title of Class:  COM
CUSIP:  53815P-10-8
Value:  13,495,744
Shrs or Prn Amt:
Ssh Prnamt:  615401
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  615401
Shared:  0
None:  0
Info Table:
Name of Issuer:  Liveramp Holdings Inc
Title of Class:  COM
CUSIP:  53815P-10-8
Value:  8,393,664
Shrs or Prn Amt:
Ssh Prnamt:  382748
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  114541
Shared:  0
None:  268207
Info Table:
Name of Issuer:  Liveramp Holdings Inc
Title of Class:  COM
CUSIP:  53815P-10-8
Value:  3,749,219
Shrs or Prn Amt:
Ssh Prnamt:  170963
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  170963
Shared:  0
None:  0
Info Table:
Name of Issuer:  Liveramp Holdings Inc
Title of Class:  COM
CUSIP:  53815P-10-8
Value:  6,470,995
Shrs or Prn Amt:
Ssh Prnamt:  295075
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  295075
Shared:  0
None:  0
Info Table:
Name of Issuer:  Logitech International SA
Title of Class:  SHS
CUSIP:  H50430-23-2
Value:  13,659
Shrs or Prn Amt:
Ssh Prnamt:  235
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  235
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lufax Holding Ltd
Title of Class:  COM
CUSIP:  54975P-10-2
Value:  11,456,754
Shrs or Prn Amt:
Ssh Prnamt:  5616056
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  5616056
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lufax Holding Ltd
Title of Class:  COM
CUSIP:  54975P-10-2
Value:  2,085,335
Shrs or Prn Amt:
Ssh Prnamt:  1022223
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  144625
Shared:  0
None:  877598
Info Table:
Name of Issuer:  Lufax Holding Ltd
Title of Class:  COM
CUSIP:  54975P-10-2
Value:  37,758,289
Shrs or Prn Amt:
Ssh Prnamt:  18508965
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  12209188
Shared:  0
None:  6299777
Info Table:
Name of Issuer:  Lyell Immunopharma Inc
Title of Class:  COM
CUSIP:  55083R-10-4
Value:  779,978
Shrs or Prn Amt:
Ssh Prnamt:  330499
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  330499
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lyell Immunopharma Inc
Title of Class:  COM
CUSIP:  55083R-10-4
Value:  311,973
Shrs or Prn Amt:
Ssh Prnamt:  132192
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  132192
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lyell Immunopharma Inc
Title of Class:  COM
CUSIP:  55083R-10-4
Value:  704,767
Shrs or Prn Amt:
Ssh Prnamt:  298630
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  298630
Shared:  0
None:  0
Info Table:
Name of Issuer:  Lyft Inc Class A Common
Title of Class:  CL A COM
CUSIP:  55087P-10-4
Value:  4,524
Shrs or Prn Amt:
Ssh Prnamt:  488
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  488
Shared:  0
None:  0
Info Table:
Name of Issuer:  MELI Kaszek Pioneer
Title of Class:  CL A COM
CUSIP:  G5S74L-10-6
Value:  20,400,000
Shrs or Prn Amt:
Ssh Prnamt:  2000000
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2000000
Shared:  0
None:  0
Info Table:
Name of Issuer:  MP Materials
Title of Class:  COM CL A
CUSIP:  553368-10-1
Value:  38,568,881
Shrs or Prn Amt:
Ssh Prnamt:  1368176
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1368176
Shared:  0
None:  0
Info Table:
Name of Issuer:  MP Materials
Title of Class:  COM CL A
CUSIP:  553368-10-1
Value:  2,886,656
Shrs or Prn Amt:
Ssh Prnamt:  102400
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  102400
Shared:  0
None:  0
Info Table:
Name of Issuer:  MakeMyTrip
Title of Class:  SHS
CUSIP:  V5633W-10-9
Value:  55,924,668
Shrs or Prn Amt:
Ssh Prnamt:  2285438
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1687249
Shared:  0
None:  598189
Info Table:
Name of Issuer:  Marathon Digital Holdings
Title of Class:  COM
CUSIP:  565788-10-6
Value:  1,744
Shrs or Prn Amt:
Ssh Prnamt:  200
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  200
Shared:  0
None:  0
Info Table:
Name of Issuer:  Markel Corp
Title of Class:  COM
CUSIP:  570535-10-4
Value:  46,016,140
Shrs or Prn Amt:
Ssh Prnamt:  36023
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  36023
Shared:  0
None:  0
Info Table:
Name of Issuer:  Markel Corp
Title of Class:  COM
CUSIP:  570535-10-4
Value:  146,255,781
Shrs or Prn Amt:
Ssh Prnamt:  114494
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  101454
Shared:  0
None:  13040
Info Table:
Name of Issuer:  Markel Corp
Title of Class:  COM
CUSIP:  570535-10-4
Value:  175,337,297
Shrs or Prn Amt:
Ssh Prnamt:  137260
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  90576
Shared:  0
None:  46684
Info Table:
Name of Issuer:  Markel Corp
Title of Class:  COM
CUSIP:  570535-10-4
Value:  37,884,148
Shrs or Prn Amt:
Ssh Prnamt:  29657
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  16491
Shared:  0
None:  13166
Info Table:
Name of Issuer:  MarketAxess Holdings
Title of Class:  COM
CUSIP:  57060D-10-8
Value:  179,423,290
Shrs or Prn Amt:
Ssh Prnamt:  458543
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  458543
Shared:  0
None:  0
Info Table:
Name of Issuer:  MarketAxess Holdings
Title of Class:  COM
CUSIP:  57060D-10-8
Value:  270,982,411
Shrs or Prn Amt:
Ssh Prnamt:  692536
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  556183
Shared:  0
None:  136353
Info Table:
Name of Issuer:  MarketAxess Holdings
Title of Class:  COM
CUSIP:  57060D-10-8
Value:  73,193,142
Shrs or Prn Amt:
Ssh Prnamt:  187056
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  187056
Shared:  0
None:  0
Info Table:
Name of Issuer:  MarketAxess Holdings
Title of Class:  COM
CUSIP:  57060D-10-8
Value:  36,055,808
Shrs or Prn Amt:
Ssh Prnamt:  92146
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  85160
Shared:  0
None:  6986
Info Table:
Name of Issuer:  Marriott International
Title of Class:  CL A
CUSIP:  571903-20-2
Value:  20,423
Shrs or Prn Amt:
Ssh Prnamt:  123
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  123
Shared:  0
None:  0
Info Table:
Name of Issuer:  Martin Marietta Materials
Title of Class:  COM
CUSIP:  573284-10-6
Value:  139,148,014
Shrs or Prn Amt:
Ssh Prnamt:  391900
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  391900
Shared:  0
None:  0
Info Table:
Name of Issuer:  Martin Marietta Materials
Title of Class:  COM
CUSIP:  573284-10-6
Value:  351,735,573
Shrs or Prn Amt:
Ssh Prnamt:  990637
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  712568
Shared:  0
None:  278069
Info Table:
Name of Issuer:  Martin Marietta Materials
Title of Class:  COM
CUSIP:  573284-10-6
Value:  96,880,606
Shrs or Prn Amt:
Ssh Prnamt:  272857
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  152675
Shared:  0
None:  120182
Info Table:
Name of Issuer:  Martin Marietta Materials
Title of Class:  COM
CUSIP:  573284-10-6
Value:  437,440,311
Shrs or Prn Amt:
Ssh Prnamt:  1232018
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1089450
Shared:  0
None:  142568
Info Table:
Name of Issuer:  Masimo Corp
Title of Class:  COM
CUSIP:  574795-10-0
Value:  6,731,650
Shrs or Prn Amt:
Ssh Prnamt:  36478
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  36478
Shared:  0
None:  0
Info Table:
Name of Issuer:  Masimo Corp
Title of Class:  COM
CUSIP:  574795-10-0
Value:  3,166,153
Shrs or Prn Amt:
Ssh Prnamt:  17157
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  17157
Shared:  0
None:  0
Info Table:
Name of Issuer:  Masimo Corp
Title of Class:  COM
CUSIP:  574795-10-0
Value:  7,820,252
Shrs or Prn Amt:
Ssh Prnamt:  42377
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  42377
Shared:  0
None:  0
Info Table:
Name of Issuer:  Mastercard Inc-Class A
Title of Class:  CL A
CUSIP:  57636Q-10-4
Value:  327,558,513
Shrs or Prn Amt:
Ssh Prnamt:  901347
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  794455
Shared:  0
None:  106892
Info Table:
Name of Issuer:  Mastercard Inc-Class A
Title of Class:  CL A
CUSIP:  57636Q-10-4
Value:  113,789,486
Shrs or Prn Amt:
Ssh Prnamt:  313116
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  313116
Shared:  0
None:  0
Info Table:
Name of Issuer:  Mastercard Inc-Class A
Title of Class:  CL A
CUSIP:  57636Q-10-4
Value:  85,660,461
Shrs or Prn Amt:
Ssh Prnamt:  235713
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  130721
Shared:  0
None:  104992
Info Table:
Name of Issuer:  Mastercard Inc-Class A
Title of Class:  CL A
CUSIP:  57636Q-10-4
Value:  381,962,807
Shrs or Prn Amt:
Ssh Prnamt:  1051052
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  674764
Shared:  0
None:  376288
Info Table:
Name of Issuer:  Materialise Nv ADR
Title of Class:  SPONSORED ADS
CUSIP:  57667T-10-0
Value:  2,224,400
Shrs or Prn Amt:
Ssh Prnamt:  268000
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  268000
Shared:  0
None:  0
Info Table:
Name of Issuer:  Mativ Inc
Title of Class:  COM
CUSIP:  808541-10-6
Value:  7,300
Shrs or Prn Amt:
Ssh Prnamt:  340
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  340
Shared:  0
None:  0
Info Table:
Name of Issuer:  MaxCyte
Title of Class:  COM
CUSIP:  57777K-10-6
Value:  1,414,459
Shrs or Prn Amt:
Ssh Prnamt:  293325
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  293325
Shared:  0
None:  0
Info Table:
Name of Issuer:  Maxlinear Inc
Title of Class:  COM
CUSIP:  57776J-10-0
Value:  16,197
Shrs or Prn Amt:
Ssh Prnamt:  460
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  460
Shared:  0
None:  0
Info Table:
Name of Issuer:  McDonald's
Title of Class:  COM
CUSIP:  580135-10-1
Value:  307,012
Shrs or Prn Amt:
Ssh Prnamt:  1098
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  1098
Info Table:
Name of Issuer:  McDonald's
Title of Class:  COM
CUSIP:  580135-10-1
Value:  13,209,615
Shrs or Prn Amt:
Ssh Prnamt:  47243
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  47243
Shared:  0
None:  0
Info Table:
Name of Issuer:  McDonald's
Title of Class:  COM
CUSIP:  580135-10-1
Value:  683,926
Shrs or Prn Amt:
Ssh Prnamt:  2446
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2446
Shared:  0
None:  0
Info Table:
Name of Issuer:  McDonald's
Title of Class:  COM
CUSIP:  580135-10-1
Value:  20,520,578
Shrs or Prn Amt:
Ssh Prnamt:  73390
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  73390
Shared:  0
None:  0
Info Table:
Name of Issuer:  Medifast Inc
Title of Class:  COM
CUSIP:  58470H-10-1
Value:  15,965
Shrs or Prn Amt:
Ssh Prnamt:  154
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  154
Shared:  0
None:  0
Info Table:
Name of Issuer:  Medtronic
Title of Class:  COM
CUSIP:  G5960L-10-3
Value:  203,807
Shrs or Prn Amt:
Ssh Prnamt:  2528
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  2528
Info Table:
Name of Issuer:  Medtronic
Title of Class:  COM
CUSIP:  G5960L-10-3
Value:  20,215,223
Shrs or Prn Amt:
Ssh Prnamt:  250747
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  250747
Shared:  0
None:  0
Info Table:
Name of Issuer:  Medtronic
Title of Class:  COM
CUSIP:  G5960L-10-3
Value:  4,106,138
Shrs or Prn Amt:
Ssh Prnamt:  50932
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  50932
Shared:  0
None:  0
Info Table:
Name of Issuer:  Medtronic
Title of Class:  COM
CUSIP:  G5960L-10-3
Value:  12,889,687
Shrs or Prn Amt:
Ssh Prnamt:  159882
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  159882
Shared:  0
None:  0
Info Table:
Name of Issuer:  MercadoLibre
Title of Class:  COM
CUSIP:  58733R-10-2
Value:  536,102,452
Shrs or Prn Amt:
Ssh Prnamt:  406736
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  406736
Shared:  0
None:  0
Info Table:
Name of Issuer:  MercadoLibre
Title of Class:  COM
CUSIP:  58733R-10-2
Value:  6,041,530,991
Shrs or Prn Amt:
Ssh Prnamt:  4583654
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  3542843
Shared:  0
None:  1040811
Info Table:
Name of Issuer:  MercadoLibre
Title of Class:  COM
CUSIP:  58733R-10-2
Value:  423,185,570
Shrs or Prn Amt:
Ssh Prnamt:  321067
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  232071
Shared:  0
None:  88996
Info Table:
Name of Issuer:  MercadoLibre
Title of Class:  COM
CUSIP:  58733R-10-2
Value:  11,076,976
Shrs or Prn Amt:
Ssh Prnamt:  8404
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  8404
Shared:  0
None:  0
Info Table:
Name of Issuer:  MercadoLibre
Title of Class:  COM
CUSIP:  58733R-10-2
Value:  1,064,718,323
Shrs or Prn Amt:
Ssh Prnamt:  807792
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  689328
Shared:  0
None:  118464
Info Table:
Name of Issuer:  Merck
Title of Class:  COM
CUSIP:  58933Y-10-5
Value:  15,746
Shrs or Prn Amt:
Ssh Prnamt:  148
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  148
Shared:  0
None:  0
Info Table:
Name of Issuer:  Meta Platforms Inc
Title of Class:  CL A
CUSIP:  30303M-10-2
Value:  58,729,422
Shrs or Prn Amt:
Ssh Prnamt:  277104
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  151250
Shared:  0
None:  125854
Info Table:
Name of Issuer:  Meta Platforms Inc
Title of Class:  CL A
CUSIP:  30303M-10-2
Value:  226,513,842
Shrs or Prn Amt:
Ssh Prnamt:  1068764
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  946558
Shared:  0
None:  122206
Info Table:
Name of Issuer:  Meta Platforms Inc
Title of Class:  CL A
CUSIP:  30303M-10-2
Value:  74,975,471
Shrs or Prn Amt:
Ssh Prnamt:  353758
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  353758
Shared:  0
None:  0
Info Table:
Name of Issuer:  Meta Platforms Inc
Title of Class:  CL A
CUSIP:  30303M-10-2
Value:  264,319,275
Shrs or Prn Amt:
Ssh Prnamt:  1247142
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  799084
Shared:  0
None:  448058
Info Table:
Name of Issuer:  Mettler-Toledo
Title of Class:  COM
CUSIP:  592688-10-5
Value:  5,404,702
Shrs or Prn Amt:
Ssh Prnamt:  3532
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2313
Shared:  0
None:  1219
Info Table:
Name of Issuer:  Mettler-Toledo
Title of Class:  COM
CUSIP:  592688-10-5
Value:  360,174,709
Shrs or Prn Amt:
Ssh Prnamt:  235376
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  173236
Shared:  0
None:  62140
Info Table:
Name of Issuer:  Mettler-Toledo
Title of Class:  COM
CUSIP:  592688-10-5
Value:  84,189,094
Shrs or Prn Amt:
Ssh Prnamt:  55018
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  55018
Shared:  0
None:  0
Info Table:
Name of Issuer:  Mettler-Toledo
Title of Class:  COM
CUSIP:  592688-10-5
Value:  38,588,836
Shrs or Prn Amt:
Ssh Prnamt:  25218
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  25218
Shared:  0
None:  0
Info Table:
Name of Issuer:  Microsoft
Title of Class:  COM
CUSIP:  594918-10-4
Value:  150,852,110
Shrs or Prn Amt:
Ssh Prnamt:  523247
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  314000
Shared:  0
None:  209247
Info Table:
Name of Issuer:  Microsoft
Title of Class:  COM
CUSIP:  594918-10-4
Value:  545,235,843
Shrs or Prn Amt:
Ssh Prnamt:  1891210
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1690577
Shared:  0
None:  200633
Info Table:
Name of Issuer:  Microsoft
Title of Class:  COM
CUSIP:  594918-10-4
Value:  247,055,802
Shrs or Prn Amt:
Ssh Prnamt:  856940
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  856940
Shared:  0
None:  0
Info Table:
Name of Issuer:  Microsoft
Title of Class:  COM
CUSIP:  594918-10-4
Value:  676,711,887
Shrs or Prn Amt:
Ssh Prnamt:  2347249
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1576963
Shared:  0
None:  770286
Info Table:
Name of Issuer:  Mirati Therapeutics
Title of Class:  COM
CUSIP:  60468T-10-5
Value:  7,957
Shrs or Prn Amt:
Ssh Prnamt:  214
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  214
Shared:  0
None:  0
Info Table:
Name of Issuer:  Mobileye Global Inc.
Title of Class:  ORD SHS
CUSIP:  60741F-10-4
Value:  267,241,361
Shrs or Prn Amt:
Ssh Prnamt:  6176135
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  5239864
Shared:  0
None:  936271
Info Table:
Name of Issuer:  Moderna Inc
Title of Class:  COM
CUSIP:  60770K-10-7
Value:  698,924,918
Shrs or Prn Amt:
Ssh Prnamt:  4550885
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  4550885
Shared:  0
None:  0
Info Table:
Name of Issuer:  Moderna Inc
Title of Class:  COM
CUSIP:  60770K-10-7
Value:  3,854,994,225
Shrs or Prn Amt:
Ssh Prnamt:  25100887
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  19514688
Shared:  0
None:  5586199
Info Table:
Name of Issuer:  Moderna Inc
Title of Class:  COM
CUSIP:  60770K-10-7
Value:  466,622,421
Shrs or Prn Amt:
Ssh Prnamt:  3038302
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2467586
Shared:  0
None:  570716
Info Table:
Name of Issuer:  Moderna Inc
Title of Class:  COM
CUSIP:  60770K-10-7
Value:  2,115,732,977
Shrs or Prn Amt:
Ssh Prnamt:  13776097
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  11755775
Shared:  0
None:  2020322
Info Table:
Name of Issuer:  Momentive Global Inc
Title of Class:  COM
CUSIP:  60878Y-10-8
Value:  12,479
Shrs or Prn Amt:
Ssh Prnamt:  1339
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1339
Shared:  0
None:  0
Info Table:
Name of Issuer:  MongoDB Inc
Title of Class:  COM
CUSIP:  60937P-10-6
Value:  1,394,058
Shrs or Prn Amt:
Ssh Prnamt:  5980
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5980
Shared:  0
None:  0
Info Table:
Name of Issuer:  MongoDB Inc
Title of Class:  COM
CUSIP:  60937P-10-6
Value:  60,378
Shrs or Prn Amt:
Ssh Prnamt:  259
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  259
Shared:  0
None:  0
Info Table:
Name of Issuer:  Monolithic Power Systems Inc
Title of Class:  COM
CUSIP:  609839-10-5
Value:  33,036
Shrs or Prn Amt:
Ssh Prnamt:  66
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  66
Shared:  0
None:  0
Info Table:
Name of Issuer:  Moody's Corp
Title of Class:  COM
CUSIP:  615369-10-5
Value:  540,737,034
Shrs or Prn Amt:
Ssh Prnamt:  1766999
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1114332
Shared:  0
None:  652667
Info Table:
Name of Issuer:  Moody's Corp
Title of Class:  COM
CUSIP:  615369-10-5
Value:  119,756,643
Shrs or Prn Amt:
Ssh Prnamt:  391336
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  213677
Shared:  0
None:  177659
Info Table:
Name of Issuer:  Moody's Corp
Title of Class:  COM
CUSIP:  615369-10-5
Value:  149,039,697
Shrs or Prn Amt:
Ssh Prnamt:  487026
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  487026
Shared:  0
None:  0
Info Table:
Name of Issuer:  Moody's Corp
Title of Class:  COM
CUSIP:  615369-10-5
Value:  456,363,036
Shrs or Prn Amt:
Ssh Prnamt:  1491285
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1322412
Shared:  0
None:  168873
Info Table:
Name of Issuer:  NIO Inc ADR
Title of Class:  SPON ADS
CUSIP:  62914V-10-6
Value:  29,773,527
Shrs or Prn Amt:
Ssh Prnamt:  2832876
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2832876
Shared:  0
None:  0
Info Table:
Name of Issuer:  NIO Inc ADR
Title of Class:  SPON ADS
CUSIP:  62914V-10-6
Value:  867,794,830
Shrs or Prn Amt:
Ssh Prnamt:  82568490
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  62592124
Shared:  0
None:  19976366
Info Table:
Name of Issuer:  NIO Inc ADR
Title of Class:  SPON ADS
CUSIP:  62914V-10-6
Value:  47,510,812
Shrs or Prn Amt:
Ssh Prnamt:  4520534
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  3861656
Shared:  0
None:  658878
Info Table:
Name of Issuer:  NIO Inc ADR
Title of Class:  SPON ADS
CUSIP:  62914V-10-6
Value:  317,514,625
Shrs or Prn Amt:
Ssh Prnamt:  30210716
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  25822064
Shared:  0
None:  4388652
Info Table:
Name of Issuer:  NVIDIA
Title of Class:  COM
CUSIP:  67066G-10-4
Value:  466,863,872
Shrs or Prn Amt:
Ssh Prnamt:  1680757
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1680757
Shared:  0
None:  0
Info Table:
Name of Issuer:  NVIDIA
Title of Class:  COM
CUSIP:  67066G-10-4
Value:  2,632,287,127
Shrs or Prn Amt:
Ssh Prnamt:  9476499
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6073365
Shared:  0
None:  3403134
Info Table:
Name of Issuer:  NVIDIA
Title of Class:  COM
CUSIP:  67066G-10-4
Value:  311,468,223
Shrs or Prn Amt:
Ssh Prnamt:  1121317
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  968557
Shared:  0
None:  152760
Info Table:
Name of Issuer:  NVIDIA
Title of Class:  COM
CUSIP:  67066G-10-4
Value:  1,036,889,855
Shrs or Prn Amt:
Ssh Prnamt:  3732908
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2770898
Shared:  0
None:  962010
Info Table:
Name of Issuer:  Nano Dimension ADR
Title of Class:  SPONS ADS
CUSIP:  63008G-20-3
Value:  4,624
Shrs or Prn Amt:
Ssh Prnamt:  1600
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1600
Shared:  0
None:  0
Info Table:
Name of Issuer:  Nanobiotix ADR
Title of Class:  COM
CUSIP:  63009J-10-7
Value:  3,088,553
Shrs or Prn Amt:
Ssh Prnamt:  850841
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  850841
Shared:  0
None:  0
Info Table:
Name of Issuer:  Nanobiotix ADR
Title of Class:  COM
CUSIP:  63009J-10-7
Value:  1,993,447
Shrs or Prn Amt:
Ssh Prnamt:  549159
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  549159
Shared:  0
None:  0
Info Table:
Name of Issuer:  Nektar Therapeutics
Title of Class:  COM
CUSIP:  640268-10-8
Value:  967
Shrs or Prn Amt:
Ssh Prnamt:  1376
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1376
Shared:  0
None:  0
Info Table:
Name of Issuer:  Netflix Inc
Title of Class:  COM
CUSIP:  64110L-10-6
Value:  322,948,485
Shrs or Prn Amt:
Ssh Prnamt:  934782
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  934782
Shared:  0
None:  0
Info Table:
Name of Issuer:  Netflix Inc
Title of Class:  COM
CUSIP:  64110L-10-6
Value:  1,184,305,440
Shrs or Prn Amt:
Ssh Prnamt:  3428000
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2061259
Shared:  0
None:  1366741
Info Table:
Name of Issuer:  Netflix Inc
Title of Class:  COM
CUSIP:  64110L-10-6
Value:  190,406,120
Shrs or Prn Amt:
Ssh Prnamt:  551135
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  458610
Shared:  0
None:  92525
Info Table:
Name of Issuer:  Netflix Inc
Title of Class:  COM
CUSIP:  64110L-10-6
Value:  613,123,701
Shrs or Prn Amt:
Ssh Prnamt:  1774701
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1267183
Shared:  0
None:  507518
Info Table:
Name of Issuer:  New Relic
Title of Class:  COM
CUSIP:  64829B-10-0
Value:  59,856
Shrs or Prn Amt:
Ssh Prnamt:  795
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  795
Shared:  0
None:  0
Info Table:
Name of Issuer:  New York Times Co
Title of Class:  COM
CUSIP:  650111-10-7
Value:  4,227,384
Shrs or Prn Amt:
Ssh Prnamt:  108729
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  108729
Shared:  0
None:  0
Info Table:
Name of Issuer:  New York Times Co
Title of Class:  COM
CUSIP:  650111-10-7
Value:  15,163
Shrs or Prn Amt:
Ssh Prnamt:  390
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  390
Shared:  0
None:  0
Info Table:
Name of Issuer:  New York Times Co
Title of Class:  COM
CUSIP:  650111-10-7
Value:  4,277,966
Shrs or Prn Amt:
Ssh Prnamt:  110030
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  110030
Shared:  0
None:  0
Info Table:
Name of Issuer:  Newmont Mining
Title of Class:  COM
CUSIP:  651639-10-6
Value:  1,855,309
Shrs or Prn Amt:
Ssh Prnamt:  37848
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  37848
Shared:  0
None:  0
Info Table:
Name of Issuer:  NextEra Energy
Title of Class:  COM
CUSIP:  65339F-10-1
Value:  3,639,178
Shrs or Prn Amt:
Ssh Prnamt:  47213
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  47213
Shared:  0
None:  0
Info Table:
Name of Issuer:  NextEra Energy
Title of Class:  COM
CUSIP:  65339F-10-1
Value:  331,675
Shrs or Prn Amt:
Ssh Prnamt:  4303
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  4303
Shared:  0
None:  0
Info Table:
Name of Issuer:  Nike
Title of Class:  COM
CUSIP:  654106-10-3
Value:  11,038
Shrs or Prn Amt:
Ssh Prnamt:  90
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  90
Shared:  0
None:  0
Info Table:
Name of Issuer:  Novanta Inc
Title of Class:  COM
CUSIP:  67000B-10-4
Value:  83,204
Shrs or Prn Amt:
Ssh Prnamt:  523
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  523
Shared:  0
None:  0
Info Table:
Name of Issuer:  Novanta Inc
Title of Class:  COM
CUSIP:  67000B-10-4
Value:  1,164,857
Shrs or Prn Amt:
Ssh Prnamt:  7322
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  7322
Shared:  0
None:  0
Info Table:
Name of Issuer:  Novavax Inc
Title of Class:  COM NEW
CUSIP:  670002-40-1
Value:  901
Shrs or Prn Amt:
Ssh Prnamt:  130
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  130
Shared:  0
None:  0
Info Table:
Name of Issuer:  Novocure Ltd
Title of Class:  ORD SHS
CUSIP:  G6674U-10-8
Value:  142,090,613
Shrs or Prn Amt:
Ssh Prnamt:  2362664
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2362664
Shared:  0
None:  0
Info Table:
Name of Issuer:  Novocure Ltd
Title of Class:  ORD SHS
CUSIP:  G6674U-10-8
Value:  221,474,812
Shrs or Prn Amt:
Ssh Prnamt:  3682654
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  3211953
Shared:  0
None:  470701
Info Table:
Name of Issuer:  Novocure Ltd
Title of Class:  ORD SHS
CUSIP:  G6674U-10-8
Value:  115,849,727
Shrs or Prn Amt:
Ssh Prnamt:  1926334
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1462571
Shared:  0
None:  463763
Info Table:
Name of Issuer:  Novocure Ltd
Title of Class:  ORD SHS
CUSIP:  G6674U-10-8
Value:  37,999,399
Shrs or Prn Amt:
Ssh Prnamt:  631849
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  507201
Shared:  0
None:  124648
Info Table:
Name of Issuer:  Nu Holdings Ltd.
Title of Class:  ORD SHS CL A
CUSIP:  G6683N-10-3
Value:  62,263,470
Shrs or Prn Amt:
Ssh Prnamt:  13080561
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  13080561
Shared:  0
None:  0
Info Table:
Name of Issuer:  Nu Holdings Ltd.
Title of Class:  ORD SHS CL A
CUSIP:  G6683N-10-3
Value:  415,111,251
Shrs or Prn Amt:
Ssh Prnamt:  87208246
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  75398637
Shared:  0
None:  11809609
Info Table:
Name of Issuer:  Nu Holdings Ltd.
Title of Class:  ORD SHS CL A
CUSIP:  G6683N-10-3
Value:  101,339,286
Shrs or Prn Amt:
Ssh Prnamt:  21289766
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  10177331
Shared:  0
None:  11112435
Info Table:
Name of Issuer:  Nu Holdings Ltd.
Title of Class:  ORD SHS CL A
CUSIP:  G6683N-10-3
Value:  18,514,339
Shrs or Prn Amt:
Ssh Prnamt:  3889567
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1201697
Shared:  0
None:  2687870
Info Table:
Name of Issuer:  Nucana Plc ADR
Title of Class:  SPONSORED ADR
CUSIP:  67022C-10-6
Value:  1,189,553
Shrs or Prn Amt:
Ssh Prnamt:  1238989
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1238989
Shared:  0
None:  0
Info Table:
Name of Issuer:  Nucana Plc ADR
Title of Class:  SPONSORED ADR
CUSIP:  67022C-10-6
Value:  2,323,481
Shrs or Prn Amt:
Ssh Prnamt:  2420041
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2420041
Shared:  0
None:  0
Info Table:
Name of Issuer:  Nutanix Inc
Title of Class:  COM
CUSIP:  67059N-10-8
Value:  18,791
Shrs or Prn Amt:
Ssh Prnamt:  723
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  723
Shared:  0
None:  0
Info Table:
Name of Issuer:  Oatly Inc.
Title of Class:  SPONS ADS
CUSIP:  67421J-10-8
Value:  89,167,702
Shrs or Prn Amt:
Ssh Prnamt:  36846158
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  30631807
Shared:  0
None:  6214351
Info Table:
Name of Issuer:  On Semiconductor Corp
Title of Class:  COM
CUSIP:  682189-10-5
Value:  50,956
Shrs or Prn Amt:
Ssh Prnamt:  619
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  619
Shared:  0
None:  0
Info Table:
Name of Issuer:  OpenDoor Technologies
Title of Class:  COM
CUSIP:  683712-10-3
Value:  12,672
Shrs or Prn Amt:
Ssh Prnamt:  7200
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  7200
Shared:  0
None:  0
Info Table:
Name of Issuer:  Opko Health Inc
Title of Class:  COM
CUSIP:  68375N-10-3
Value:  9,687
Shrs or Prn Amt:
Ssh Prnamt:  6635
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  6635
Shared:  0
None:  0
Info Table:
Name of Issuer:  Oscar Health Inc
Title of Class:  COM
CUSIP:  687793-10-9
Value:  335,600
Shrs or Prn Amt:
Ssh Prnamt:  51315
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  51315
Shared:  0
None:  0
Info Table:
Name of Issuer:  Oscar Health Inc
Title of Class:  COM
CUSIP:  687793-10-9
Value:  729,694
Shrs or Prn Amt:
Ssh Prnamt:  111574
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  111574
Shared:  0
None:  0
Info Table:
Name of Issuer:  Oscar Health Inc
Title of Class:  COM
CUSIP:  687793-10-9
Value:  5,376,456
Shrs or Prn Amt:
Ssh Prnamt:  822088
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  822088
Shared:  0
None:  0
Info Table:
Name of Issuer:  Oscar Health Inc
Title of Class:  COM
CUSIP:  687793-10-9
Value:  786,893
Shrs or Prn Amt:
Ssh Prnamt:  120320
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  120320
Shared:  0
None:  0
Info Table:
Name of Issuer:  Outset Medical
Title of Class:  COM
CUSIP:  690145-10-7
Value:  7,102
Shrs or Prn Amt:
Ssh Prnamt:  386
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  386
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ozon Holdings ADR
Title of Class:  COM
CUSIP:  69269L-10-4
Value:  0
Shrs or Prn Amt:
Ssh Prnamt:  2307811
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1289275
Shared:  0
None:  1018536
Info Table:
Name of Issuer:  Ozon Holdings ADR
Title of Class:  COM
CUSIP:  69269L-10-4
Value:  0
Shrs or Prn Amt:
Ssh Prnamt:  333970
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  333970
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ozon Holdings ADR
Title of Class:  COM
CUSIP:  69269L-10-4
Value:  0
Shrs or Prn Amt:
Ssh Prnamt:  19278
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  19278
Shared:  0
None:  0
Info Table:
Name of Issuer:  PDD Holdings Inc
Title of Class:  SPONSORED ADS
CUSIP:  722304-10-2
Value:  1,208,946,130
Shrs or Prn Amt:
Ssh Prnamt:  15928144
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  8663052
Shared:  0
None:  7265092
Info Table:
Name of Issuer:  PDD Holdings Inc
Title of Class:  SPONSORED ADS
CUSIP:  722304-10-2
Value:  109,683,014
Shrs or Prn Amt:
Ssh Prnamt:  1445099
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1445099
Shared:  0
None:  0
Info Table:
Name of Issuer:  PDD Holdings Inc
Title of Class:  SPONSORED ADS
CUSIP:  722304-10-2
Value:  182,120,760
Shrs or Prn Amt:
Ssh Prnamt:  2399483
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2081017
Shared:  0
None:  318466
Info Table:
Name of Issuer:  PDD Holdings Inc
Title of Class:  SPONSORED ADS
CUSIP:  722304-10-2
Value:  638,965,516
Shrs or Prn Amt:
Ssh Prnamt:  8418518
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  6291211
Shared:  0
None:  2127307
Info Table:
Name of Issuer:  PROCEPT BioRobotics
Title of Class:  COM
CUSIP:  74276L-10-5
Value:  12,354
Shrs or Prn Amt:
Ssh Prnamt:  435
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  435
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pacira BioSciences
Title of Class:  COM
CUSIP:  695127-10-0
Value:  29,308,436
Shrs or Prn Amt:
Ssh Prnamt:  718168
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  718168
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pacira BioSciences
Title of Class:  COM
CUSIP:  695127-10-0
Value:  12,651,386
Shrs or Prn Amt:
Ssh Prnamt:  310007
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  310007
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pacira BioSciences
Title of Class:  COM
CUSIP:  695127-10-0
Value:  23,998,933
Shrs or Prn Amt:
Ssh Prnamt:  588065
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  189848
Shared:  0
None:  398217
Info Table:
Name of Issuer:  Pacira BioSciences
Title of Class:  COM
CUSIP:  695127-10-0
Value:  11,206,467
Shrs or Prn Amt:
Ssh Prnamt:  274601
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  235428
Shared:  0
None:  39173
Info Table:
Name of Issuer:  PagerDuty
Title of Class:  COM
CUSIP:  69553P-10-0
Value:  19,764
Shrs or Prn Amt:
Ssh Prnamt:  565
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  565
Shared:  0
None:  0
Info Table:
Name of Issuer:  Paychex
Title of Class:  COM
CUSIP:  704326-10-7
Value:  15,699
Shrs or Prn Amt:
Ssh Prnamt:  137
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  137
Shared:  0
None:  0
Info Table:
Name of Issuer:  Peloton Interactive Inc
Title of Class:  CL A COM
CUSIP:  70614W-10-0
Value:  5,147,702
Shrs or Prn Amt:
Ssh Prnamt:  453942
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  284216
Shared:  0
None:  169726
Info Table:
Name of Issuer:  Peloton Interactive Inc
Title of Class:  CL A COM
CUSIP:  70614W-10-0
Value:  7,767,764
Shrs or Prn Amt:
Ssh Prnamt:  684988
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  684988
Shared:  0
None:  0
Info Table:
Name of Issuer:  Peloton Interactive Inc
Title of Class:  CL A COM
CUSIP:  70614W-10-0
Value:  8,289,302
Shrs or Prn Amt:
Ssh Prnamt:  730979
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  568266
Shared:  0
None:  162713
Info Table:
Name of Issuer:  Peloton Interactive Inc
Title of Class:  CL A COM
CUSIP:  70614W-10-0
Value:  2,475,669
Shrs or Prn Amt:
Ssh Prnamt:  218313
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  64753
Shared:  0
None:  153560
Info Table:
Name of Issuer:  Penumbra Inc
Title of Class:  COM
CUSIP:  70975L-10-7
Value:  108,745,395
Shrs or Prn Amt:
Ssh Prnamt:  390202
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  386423
Shared:  0
None:  3779
Info Table:
Name of Issuer:  Penumbra Inc
Title of Class:  COM
CUSIP:  70975L-10-7
Value:  74,651,018
Shrs or Prn Amt:
Ssh Prnamt:  267864
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  267864
Shared:  0
None:  0
Info Table:
Name of Issuer:  Penumbra Inc
Title of Class:  COM
CUSIP:  70975L-10-7
Value:  4,689,238
Shrs or Prn Amt:
Ssh Prnamt:  16826
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  16826
Shared:  0
None:  0
Info Table:
Name of Issuer:  Penumbra Inc
Title of Class:  COM
CUSIP:  70975L-10-7
Value:  14,899,882
Shrs or Prn Amt:
Ssh Prnamt:  53464
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  53464
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pepsico
Title of Class:  COM
CUSIP:  713448-10-8
Value:  595,210
Shrs or Prn Amt:
Ssh Prnamt:  3265
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  3265
Info Table:
Name of Issuer:  Pepsico
Title of Class:  COM
CUSIP:  713448-10-8
Value:  66,053,853
Shrs or Prn Amt:
Ssh Prnamt:  362336
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  362336
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pepsico
Title of Class:  COM
CUSIP:  713448-10-8
Value:  14,197,524
Shrs or Prn Amt:
Ssh Prnamt:  77880
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  77880
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pepsico
Title of Class:  COM
CUSIP:  713448-10-8
Value:  38,907,560
Shrs or Prn Amt:
Ssh Prnamt:  213426
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  213426
Shared:  0
None:  0
Info Table:
Name of Issuer:  Petrobras Common ADR
Title of Class:  SPONSORED ADR
CUSIP:  71654V-40-8
Value:  121,285,495
Shrs or Prn Amt:
Ssh Prnamt:  11628523
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  11628523
Shared:  0
None:  0
Info Table:
Name of Issuer:  Petrobras Common ADR
Title of Class:  SPONSORED ADR
CUSIP:  71654V-40-8
Value:  427,436,482
Shrs or Prn Amt:
Ssh Prnamt:  40981446
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  21974375
Shared:  0
None:  19007071
Info Table:
Name of Issuer:  Petrobras Common ADR
Title of Class:  SPONSORED ADR
CUSIP:  71654V-40-8
Value:  39,195,752
Shrs or Prn Amt:
Ssh Prnamt:  3757982
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1577943
Shared:  0
None:  2180039
Info Table:
Name of Issuer:  Petrobras Common ADR
Title of Class:  SPONSORED ADR
CUSIP:  71654V-40-8
Value:  7,031,624
Shrs or Prn Amt:
Ssh Prnamt:  674173
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  674173
Shared:  0
None:  0
Info Table:
Name of Issuer:  Petrobras Common ADR
Title of Class:  SPONSORED ADR
CUSIP:  71654V-40-8
Value:  6,587,369
Shrs or Prn Amt:
Ssh Prnamt:  631579
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  631579
Shared:  0
None:  0
Info Table:
Name of Issuer:  Petrobras Pref ADR
Title of Class:  SP ADR NON VTG
CUSIP:  71654V-10-1
Value:  12,108,795
Shrs or Prn Amt:
Ssh Prnamt:  1304827
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1304827
Shared:  0
None:  0
Info Table:
Name of Issuer:  Petrobras Pref ADR
Title of Class:  SP ADR NON VTG
CUSIP:  71654V-10-1
Value:  74,169,064
Shrs or Prn Amt:
Ssh Prnamt:  7992356
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6340289
Shared:  0
None:  1652067
Info Table:
Name of Issuer:  Petrobras Pref ADR
Title of Class:  SP ADR NON VTG
CUSIP:  71654V-10-1
Value:  6,709,728
Shrs or Prn Amt:
Ssh Prnamt:  723031
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  60763
Shared:  0
None:  662268
Info Table:
Name of Issuer:  Pfizer
Title of Class:  COM
CUSIP:  717081-10-3
Value:  19,013
Shrs or Prn Amt:
Ssh Prnamt:  466
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  466
Shared:  0
None:  0
Info Table:
Name of Issuer:  PhenomeX Inc
Title of Class:  COM
CUSIP:  084310-10-1
Value:  521,749
Shrs or Prn Amt:
Ssh Prnamt:  449784
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  449784
Shared:  0
None:  0
Info Table:
Name of Issuer:  PhenomeX Inc
Title of Class:  COM
CUSIP:  084310-10-1
Value:  339,472
Shrs or Prn Amt:
Ssh Prnamt:  292648
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  292648
Shared:  0
None:  0
Info Table:
Name of Issuer:  PhenomeX Inc
Title of Class:  COM
CUSIP:  084310-10-1
Value:  414,902
Shrs or Prn Amt:
Ssh Prnamt:  357674
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  357674
Shared:  0
None:  0
Info Table:
Name of Issuer:  PhenomeX Inc
Title of Class:  COM
CUSIP:  084310-10-1
Value:  286,260
Shrs or Prn Amt:
Ssh Prnamt:  246776
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  246776
Shared:  0
None:  0
Info Table:
Name of Issuer:  Physicians Realty Trust
Title of Class:  COM
CUSIP:  71943U-10-4
Value:  419,847
Shrs or Prn Amt:
Ssh Prnamt:  28121
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  28121
Shared:  0
None:  0
Info Table:
Name of Issuer:  Piedmont Lithium Inc
Title of Class:  COM
CUSIP:  72016P-10-5
Value:  15,073
Shrs or Prn Amt:
Ssh Prnamt:  251
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  251
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pinterest
Title of Class:  COM
CUSIP:  72352L-10-6
Value:  86,025,260
Shrs or Prn Amt:
Ssh Prnamt:  3154575
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3154575
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pinterest
Title of Class:  COM
CUSIP:  72352L-10-6
Value:  129,887,228
Shrs or Prn Amt:
Ssh Prnamt:  4763008
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4716684
Shared:  0
None:  46324
Info Table:
Name of Issuer:  Pinterest
Title of Class:  COM
CUSIP:  72352L-10-6
Value:  5,492,423
Shrs or Prn Amt:
Ssh Prnamt:  201409
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  201409
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pinterest
Title of Class:  COM
CUSIP:  72352L-10-6
Value:  18,175,755
Shrs or Prn Amt:
Ssh Prnamt:  666511
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  666511
Shared:  0
None:  0
Info Table:
Name of Issuer:  Precision BioSciences Inc
Title of Class:  COM
CUSIP:  74019P-10-8
Value:  3,061
Shrs or Prn Amt:
Ssh Prnamt:  4062
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4062
Shared:  0
None:  0
Info Table:
Name of Issuer:  Precision BioSciences Inc
Title of Class:  COM
CUSIP:  74019P-10-8
Value:  42,713
Shrs or Prn Amt:
Ssh Prnamt:  56678
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  56678
Shared:  0
None:  0
Info Table:
Name of Issuer:  Procter & Gamble
Title of Class:  COM
CUSIP:  742718-10-9
Value:  70,758,597
Shrs or Prn Amt:
Ssh Prnamt:  475880
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  475880
Shared:  0
None:  0
Info Table:
Name of Issuer:  Procter & Gamble
Title of Class:  COM
CUSIP:  742718-10-9
Value:  636,393
Shrs or Prn Amt:
Ssh Prnamt:  4280
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  4280
Info Table:
Name of Issuer:  Procter & Gamble
Title of Class:  COM
CUSIP:  742718-10-9
Value:  41,353,811
Shrs or Prn Amt:
Ssh Prnamt:  278121
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  278121
Shared:  0
None:  0
Info Table:
Name of Issuer:  Procter & Gamble
Title of Class:  COM
CUSIP:  742718-10-9
Value:  15,271,206
Shrs or Prn Amt:
Ssh Prnamt:  102705
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  102705
Shared:  0
None:  0
Info Table:
Name of Issuer:  Progressive
Title of Class:  COM
CUSIP:  743315-10-3
Value:  28,898
Shrs or Prn Amt:
Ssh Prnamt:  202
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  202
Shared:  0
None:  0
Info Table:
Name of Issuer:  Progressive
Title of Class:  COM
CUSIP:  743315-10-3
Value:  9,525,793
Shrs or Prn Amt:
Ssh Prnamt:  66586
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  66586
Shared:  0
None:  0
Info Table:
Name of Issuer:  Progressive
Title of Class:  COM
CUSIP:  743315-10-3
Value:  7,841,262
Shrs or Prn Amt:
Ssh Prnamt:  54811
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  54811
Shared:  0
None:  0
Info Table:
Name of Issuer:  Progyny
Title of Class:  COM
CUSIP:  74340E-10-3
Value:  17,696,257
Shrs or Prn Amt:
Ssh Prnamt:  550942
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  171720
Shared:  0
None:  379222
Info Table:
Name of Issuer:  Progyny
Title of Class:  COM
CUSIP:  74340E-10-3
Value:  19,854,753
Shrs or Prn Amt:
Ssh Prnamt:  618143
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  618143
Shared:  0
None:  0
Info Table:
Name of Issuer:  Progyny
Title of Class:  COM
CUSIP:  74340E-10-3
Value:  7,710,053
Shrs or Prn Amt:
Ssh Prnamt:  240039
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  214131
Shared:  0
None:  25908
Info Table:
Name of Issuer:  Progyny
Title of Class:  COM
CUSIP:  74340E-10-3
Value:  7,432,086
Shrs or Prn Amt:
Ssh Prnamt:  231385
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  231385
Shared:  0
None:  0
Info Table:
Name of Issuer:  Prologis Inc REIT
Title of Class:  COM
CUSIP:  74340W-10-3
Value:  35,099,797
Shrs or Prn Amt:
Ssh Prnamt:  281316
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  281316
Shared:  0
None:  0
Info Table:
Name of Issuer:  Prologis Inc REIT
Title of Class:  COM
CUSIP:  74340W-10-3
Value:  3,474,969
Shrs or Prn Amt:
Ssh Prnamt:  27851
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  27851
Shared:  0
None:  0
Info Table:
Name of Issuer:  Proterra Inc
Title of Class:  COM
CUSIP:  74374T-10-9
Value:  18,857
Shrs or Prn Amt:
Ssh Prnamt:  12406
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  12406
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ptc Therapeutics Inc
Title of Class:  COM
CUSIP:  69366J-20-0
Value:  13,466
Shrs or Prn Amt:
Ssh Prnamt:  278
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  278
Shared:  0
None:  0
Info Table:
Name of Issuer:  Pure Storage Inc
Title of Class:  COM
CUSIP:  74624M-10-2
Value:  37,755
Shrs or Prn Amt:
Ssh Prnamt:  1480
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1480
Shared:  0
None:  0
Info Table:
Name of Issuer:  Q2 Holdings Inc
Title of Class:  COM
CUSIP:  74736L-10-9
Value:  3,360,852
Shrs or Prn Amt:
Ssh Prnamt:  136509
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  136509
Shared:  0
None:  0
Info Table:
Name of Issuer:  Q2 Holdings Inc
Title of Class:  COM
CUSIP:  74736L-10-9
Value:  4,394,104
Shrs or Prn Amt:
Ssh Prnamt:  178477
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  52776
Shared:  0
None:  125701
Info Table:
Name of Issuer:  Q2 Holdings Inc
Title of Class:  COM
CUSIP:  74736L-10-9
Value:  1,972,234
Shrs or Prn Amt:
Ssh Prnamt:  80107
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  80107
Shared:  0
None:  0
Info Table:
Name of Issuer:  Q2 Holdings Inc
Title of Class:  COM
CUSIP:  74736L-10-9
Value:  3,009,426
Shrs or Prn Amt:
Ssh Prnamt:  122235
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  122235
Shared:  0
None:  0
Info Table:
Name of Issuer:  Qualcomm
Title of Class:  COM
CUSIP:  747525-10-3
Value:  25,771
Shrs or Prn Amt:
Ssh Prnamt:  202
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  202
Shared:  0
None:  0
Info Table:
Name of Issuer:  Quanterix Corp
Title of Class:  COM
CUSIP:  74766Q-10-1
Value:  4,408,091
Shrs or Prn Amt:
Ssh Prnamt:  391135
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  391135
Shared:  0
None:  0
Info Table:
Name of Issuer:  Quanterix Corp
Title of Class:  COM
CUSIP:  74766Q-10-1
Value:  23,351
Shrs or Prn Amt:
Ssh Prnamt:  2072
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2072
Shared:  0
None:  0
Info Table:
Name of Issuer:  Quanterix Corp
Title of Class:  COM
CUSIP:  74766Q-10-1
Value:  2,363,060
Shrs or Prn Amt:
Ssh Prnamt:  209677
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  209677
Shared:  0
None:  0
Info Table:
Name of Issuer:  Quanterix Corp
Title of Class:  COM
CUSIP:  74766Q-10-1
Value:  326,977
Shrs or Prn Amt:
Ssh Prnamt:  29013
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  29013
Shared:  0
None:  0
Info Table:
Name of Issuer:  QuantumScape Corp
Title of Class:  COM CL A
CUSIP:  74767V-10-9
Value:  2,856,865
Shrs or Prn Amt:
Ssh Prnamt:  349250
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  349250
Shared:  0
None:  0
Info Table:
Name of Issuer:  QuantumScape Corp
Title of Class:  COM CL A
CUSIP:  74767V-10-9
Value:  7,470,622
Shrs or Prn Amt:
Ssh Prnamt:  913279
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  913279
Shared:  0
None:  0
Info Table:
Name of Issuer:  Quest Diagnostics
Title of Class:  COM
CUSIP:  74834L-10-0
Value:  24,193
Shrs or Prn Amt:
Ssh Prnamt:  171
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  171
Shared:  0
None:  0
Info Table:
Name of Issuer:  Quidel Corp
Title of Class:  COM
CUSIP:  219798-10-5
Value:  11,404
Shrs or Prn Amt:
Ssh Prnamt:  128
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  128
Shared:  0
None:  0
Info Table:
Name of Issuer:  REGENXBIO
Title of Class:  COM
CUSIP:  75901B-10-7
Value:  15,449
Shrs or Prn Amt:
Ssh Prnamt:  817
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  817
Shared:  0
None:  0
Info Table:
Name of Issuer:  Rambus Inc
Title of Class:  COM
CUSIP:  750917-10-6
Value:  37,932
Shrs or Prn Amt:
Ssh Prnamt:  740
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  740
Shared:  0
None:  0
Info Table:
Name of Issuer:  Recursion Pharmaceuticals Inc
Title of Class:  CL A
CUSIP:  75629V-10-4
Value:  31,980,896
Shrs or Prn Amt:
Ssh Prnamt:  4794737
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4753348
Shared:  0
None:  41389
Info Table:
Name of Issuer:  Recursion Pharmaceuticals Inc
Title of Class:  CL A
CUSIP:  75629V-10-4
Value:  20,445,684
Shrs or Prn Amt:
Ssh Prnamt:  3065320
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3065320
Shared:  0
None:  0
Info Table:
Name of Issuer:  Recursion Pharmaceuticals Inc
Title of Class:  CL A
CUSIP:  75629V-10-4
Value:  4,035,777
Shrs or Prn Amt:
Ssh Prnamt:  605064
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  605064
Shared:  0
None:  0
Info Table:
Name of Issuer:  Recursion Pharmaceuticals Inc
Title of Class:  CL A
CUSIP:  75629V-10-4
Value:  111,191,628
Shrs or Prn Amt:
Ssh Prnamt:  16670409
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  16670409
Shared:  0
None:  0
Info Table:
Name of Issuer:  Redfin
Title of Class:  COM
CUSIP:  75737F-10-8
Value:  5,870,681
Shrs or Prn Amt:
Ssh Prnamt:  647978
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  647978
Shared:  0
None:  0
Info Table:
Name of Issuer:  Redfin
Title of Class:  COM
CUSIP:  75737F-10-8
Value:  2,106,332
Shrs or Prn Amt:
Ssh Prnamt:  232487
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  232487
Shared:  0
None:  0
Info Table:
Name of Issuer:  Redfin
Title of Class:  COM
CUSIP:  75737F-10-8
Value:  45,078,257
Shrs or Prn Amt:
Ssh Prnamt:  4975525
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4926684
Shared:  0
None:  48841
Info Table:
Name of Issuer:  Redfin
Title of Class:  COM
CUSIP:  75737F-10-8
Value:  29,576,098
Shrs or Prn Amt:
Ssh Prnamt:  3264470
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3264470
Shared:  0
None:  0
Info Table:
Name of Issuer:  Regeneron Pharmaceuticals
Title of Class:  COM
CUSIP:  75886F-10-7
Value:  44,370
Shrs or Prn Amt:
Ssh Prnamt:  54
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  54
Shared:  0
None:  0
Info Table:
Name of Issuer:  Relay Therapeutics Inc
Title of Class:  COM
CUSIP:  75943R-10-2
Value:  1,217,660
Shrs or Prn Amt:
Ssh Prnamt:  73932
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  73932
Shared:  0
None:  0
Info Table:
Name of Issuer:  Relay Therapeutics Inc
Title of Class:  COM
CUSIP:  75943R-10-2
Value:  2,973,807
Shrs or Prn Amt:
Ssh Prnamt:  180559
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  180559
Shared:  0
None:  0
Info Table:
Name of Issuer:  Relay Therapeutics Inc
Title of Class:  COM
CUSIP:  75943R-10-2
Value:  2,654,503
Shrs or Prn Amt:
Ssh Prnamt:  161172
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  161172
Shared:  0
None:  0
Info Table:
Name of Issuer:  Remitly Global Inc
Title of Class:  COM
CUSIP:  75960P-10-4
Value:  23,620,757
Shrs or Prn Amt:
Ssh Prnamt:  1393555
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  871778
Shared:  0
None:  521777
Info Table:
Name of Issuer:  Remitly Global Inc
Title of Class:  COM
CUSIP:  75960P-10-4
Value:  36,675,376
Shrs or Prn Amt:
Ssh Prnamt:  2163739
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1701683
Shared:  0
None:  462056
Info Table:
Name of Issuer:  Remitly Global Inc
Title of Class:  COM
CUSIP:  75960P-10-4
Value:  13,068,535
Shrs or Prn Amt:
Ssh Prnamt:  771005
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  341677
Shared:  0
None:  429328
Info Table:
Name of Issuer:  Remitly Global Inc
Title of Class:  COM
CUSIP:  75960P-10-4
Value:  36,913,371
Shrs or Prn Amt:
Ssh Prnamt:  2177780
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2177780
Shared:  0
None:  0
Info Table:
Name of Issuer:  ResMed
Title of Class:  COM
CUSIP:  761152-10-7
Value:  2,641,457
Shrs or Prn Amt:
Ssh Prnamt:  12062
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  12062
Shared:  0
None:  0
Info Table:
Name of Issuer:  ResMed
Title of Class:  COM
CUSIP:  761152-10-7
Value:  5,639,430
Shrs or Prn Amt:
Ssh Prnamt:  25752
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  25752
Shared:  0
None:  0
Info Table:
Name of Issuer:  ResMed
Title of Class:  COM
CUSIP:  761152-10-7
Value:  6,488,455
Shrs or Prn Amt:
Ssh Prnamt:  29629
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  29629
Shared:  0
None:  0
Info Table:
Name of Issuer:  Research in Motion
Title of Class:  COM
CUSIP:  09228F-10-3
Value:  11,099
Shrs or Prn Amt:
Ssh Prnamt:  2434
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2434
Shared:  0
None:  0
Info Table:
Name of Issuer:  Rexford Industrial Realty REIT
Title of Class:  COM
CUSIP:  76169C-10-0
Value:  40,364,260
Shrs or Prn Amt:
Ssh Prnamt:  676685
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  676685
Shared:  0
None:  0
Info Table:
Name of Issuer:  Rexford Industrial Realty REIT
Title of Class:  COM
CUSIP:  76169C-10-0
Value:  4,299,691
Shrs or Prn Amt:
Ssh Prnamt:  72082
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  72082
Shared:  0
None:  0
Info Table:
Name of Issuer:  Rio Tinto Spn.Adr 1:1
Title of Class:  SPONSORED ADR
CUSIP:  767204-10-0
Value:  8,781
Shrs or Prn Amt:
Ssh Prnamt:  128
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  128
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ritchie Bros Auctioneers (USA)
Title of Class:  COM
CUSIP:  767744-10-5
Value:  50,133,732
Shrs or Prn Amt:
Ssh Prnamt:  890633
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  798486
Shared:  0
None:  92147
Info Table:
Name of Issuer:  Ritchie Bros Auctioneers (USA)
Title of Class:  COM
CUSIP:  767744-10-5
Value:  2,477
Shrs or Prn Amt:
Ssh Prnamt:  44
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  44
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ritchie Bros. Auctioneers
Title of Class:  COM
CUSIP:  767744-10-5
Value:  36,426,270
Shrs or Prn Amt:
Ssh Prnamt:  648310
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  372885
Shared:  0
None:  275425
Info Table:
Name of Issuer:  Rivian Automotive Inc
Title of Class:  COM CL A
CUSIP:  76954A-10-3
Value:  17,758,997
Shrs or Prn Amt:
Ssh Prnamt:  1147222
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1147222
Shared:  0
None:  0
Info Table:
Name of Issuer:  Rivian Automotive Inc
Title of Class:  COM CL A
CUSIP:  76954A-10-3
Value:  27,890,734
Shrs or Prn Amt:
Ssh Prnamt:  1801727
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1784108
Shared:  0
None:  17619
Info Table:
Name of Issuer:  Rivian Automotive Inc
Title of Class:  COM CL A
CUSIP:  76954A-10-3
Value:  1,209,669
Shrs or Prn Amt:
Ssh Prnamt:  78144
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  78144
Shared:  0
None:  0
Info Table:
Name of Issuer:  Rivian Automotive Inc
Title of Class:  COM CL A
CUSIP:  76954A-10-3
Value:  4,218,037
Shrs or Prn Amt:
Ssh Prnamt:  272483
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  272483
Shared:  0
None:  0
Info Table:
Name of Issuer:  Robert Half International Inc
Title of Class:  COM
CUSIP:  770323-10-3
Value:  10,555
Shrs or Prn Amt:
Ssh Prnamt:  131
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  131
Shared:  0
None:  0
Info Table:
Name of Issuer:  Roblox
Title of Class:  CL A
CUSIP:  771049-10-3
Value:  336,242,098
Shrs or Prn Amt:
Ssh Prnamt:  7475369
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5537269
Shared:  0
None:  1938100
Info Table:
Name of Issuer:  Roblox
Title of Class:  CL A
CUSIP:  771049-10-3
Value:  180,739,266
Shrs or Prn Amt:
Ssh Prnamt:  4018214
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  4018214
Shared:  0
None:  0
Info Table:
Name of Issuer:  Roblox
Title of Class:  CL A
CUSIP:  771049-10-3
Value:  689,544,480
Shrs or Prn Amt:
Ssh Prnamt:  15330024
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  8948188
Shared:  0
None:  6381836
Info Table:
Name of Issuer:  Roblox
Title of Class:  CL A
CUSIP:  771049-10-3
Value:  98,058,829
Shrs or Prn Amt:
Ssh Prnamt:  2180054
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1891307
Shared:  0
None:  288747
Info Table:
Name of Issuer:  Roku
Title of Class:  COM CL A
CUSIP:  77543R-10-2
Value:  123,153,103
Shrs or Prn Amt:
Ssh Prnamt:  1871059
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1853066
Shared:  0
None:  17993
Info Table:
Name of Issuer:  Roku
Title of Class:  COM CL A
CUSIP:  77543R-10-2
Value:  16,364,958
Shrs or Prn Amt:
Ssh Prnamt:  248632
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  248632
Shared:  0
None:  0
Info Table:
Name of Issuer:  Roku
Title of Class:  COM CL A
CUSIP:  77543R-10-2
Value:  5,208,402
Shrs or Prn Amt:
Ssh Prnamt:  79131
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  79131
Shared:  0
None:  0
Info Table:
Name of Issuer:  Roku
Title of Class:  COM CL A
CUSIP:  77543R-10-2
Value:  79,036,919
Shrs or Prn Amt:
Ssh Prnamt:  1200804
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1200804
Shared:  0
None:  0
Info Table:
Name of Issuer:  Rollins Inc
Title of Class:  COM
CUSIP:  775711-10-4
Value:  23,381
Shrs or Prn Amt:
Ssh Prnamt:  623
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  623
Shared:  0
None:  0
Info Table:
Name of Issuer:  Royalty Pharma
Title of Class:  SHS CLASS A
CUSIP:  G7709Q-10-4
Value:  64,001,062
Shrs or Prn Amt:
Ssh Prnamt:  1776327
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  978224
Shared:  0
None:  798103
Info Table:
Name of Issuer:  Royalty Pharma
Title of Class:  SHS CLASS A
CUSIP:  G7709Q-10-4
Value:  80,594,354
Shrs or Prn Amt:
Ssh Prnamt:  2236868
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2236868
Shared:  0
None:  0
Info Table:
Name of Issuer:  Royalty Pharma
Title of Class:  SHS CLASS A
CUSIP:  G7709Q-10-4
Value:  292,650,648
Shrs or Prn Amt:
Ssh Prnamt:  8122416
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5275552
Shared:  0
None:  2846864
Info Table:
Name of Issuer:  Royalty Pharma
Title of Class:  SHS CLASS A
CUSIP:  G7709Q-10-4
Value:  244,396,498
Shrs or Prn Amt:
Ssh Prnamt:  6783139
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6003806
Shared:  0
None:  779333
Info Table:
Name of Issuer:  Ryanair ADR
Title of Class:  SPONSORED ADR NE
CUSIP:  783513-20-3
Value:  11,598
Shrs or Prn Amt:
Ssh Prnamt:  123
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  123
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ryanair ADR
Title of Class:  SPONSORED ADR NE
CUSIP:  783513-20-3
Value:  25,789,069
Shrs or Prn Amt:
Ssh Prnamt:  273508
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  273508
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ryanair ADR
Title of Class:  SPONSORED ADR NE
CUSIP:  783513-20-3
Value:  707,853,322
Shrs or Prn Amt:
Ssh Prnamt:  7507194
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  6348430
Shared:  0
None:  1158764
Info Table:
Name of Issuer:  Ryanair ADR
Title of Class:  SPONSORED ADR NE
CUSIP:  783513-20-3
Value:  8,771,893
Shrs or Prn Amt:
Ssh Prnamt:  93031
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  93031
Shared:  0
None:  0
Info Table:
Name of Issuer:  Ryanair ADR
Title of Class:  SPONSORED ADR NE
CUSIP:  783513-20-3
Value:  10,786,870
Shrs or Prn Amt:
Ssh Prnamt:  114401
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  104664
Shared:  0
None:  9737
Info Table:
Name of Issuer:  S&P Global Inc
Title of Class:  COM
CUSIP:  78409V-10-4
Value:  215,994,957
Shrs or Prn Amt:
Ssh Prnamt:  626490
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  408613
Shared:  0
None:  217877
Info Table:
Name of Issuer:  S&P Global Inc
Title of Class:  COM
CUSIP:  78409V-10-4
Value:  46,026,450
Shrs or Prn Amt:
Ssh Prnamt:  133499
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  72937
Shared:  0
None:  60562
Info Table:
Name of Issuer:  S&P Global Inc
Title of Class:  COM
CUSIP:  78409V-10-4
Value:  183,666,219
Shrs or Prn Amt:
Ssh Prnamt:  532721
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  474170
Shared:  0
None:  58551
Info Table:
Name of Issuer:  S&P Global Inc
Title of Class:  COM
CUSIP:  78409V-10-4
Value:  57,399,723
Shrs or Prn Amt:
Ssh Prnamt:  166487
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  166487
Shared:  0
None:  0
Info Table:
Name of Issuer:  SCP Pool Corporation
Title of Class:  COM
CUSIP:  73278L-10-5
Value:  26,934,961
Shrs or Prn Amt:
Ssh Prnamt:  78656
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  78656
Shared:  0
None:  0
Info Table:
Name of Issuer:  SCP Pool Corporation
Title of Class:  COM
CUSIP:  73278L-10-5
Value:  80,779,884
Shrs or Prn Amt:
Ssh Prnamt:  235895
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  208003
Shared:  0
None:  27892
Info Table:
Name of Issuer:  SCP Pool Corporation
Title of Class:  COM
CUSIP:  73278L-10-5
Value:  96,519,111
Shrs or Prn Amt:
Ssh Prnamt:  281857
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  180731
Shared:  0
None:  101126
Info Table:
Name of Issuer:  SCP Pool Corporation
Title of Class:  COM
CUSIP:  73278L-10-5
Value:  21,794,936
Shrs or Prn Amt:
Ssh Prnamt:  63646
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  35190
Shared:  0
None:  28456
Info Table:
Name of Issuer:  SKYWORKS SOLUTIONS, INC.
Title of Class:  COM
CUSIP:  83088M-10-2
Value:  16,045
Shrs or Prn Amt:
Ssh Prnamt:  136
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  136
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sage Therapeutics Inc
Title of Class:  COM
CUSIP:  78667J-10-8
Value:  1,534,183
Shrs or Prn Amt:
Ssh Prnamt:  36563
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  36563
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sage Therapeutics Inc
Title of Class:  COM
CUSIP:  78667J-10-8
Value:  692,760
Shrs or Prn Amt:
Ssh Prnamt:  16510
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  16510
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sage Therapeutics Inc
Title of Class:  COM
CUSIP:  78667J-10-8
Value:  1,761,145
Shrs or Prn Amt:
Ssh Prnamt:  41972
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  41972
Shared:  0
None:  0
Info Table:
Name of Issuer:  Samsara
Title of Class:  COM CL A
CUSIP:  79589L-10-6
Value:  26,206,224
Shrs or Prn Amt:
Ssh Prnamt:  1328916
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1328916
Shared:  0
None:  0
Info Table:
Name of Issuer:  Samsara
Title of Class:  COM CL A
CUSIP:  79589L-10-6
Value:  227,961,839
Shrs or Prn Amt:
Ssh Prnamt:  11559931
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4840070
Shared:  0
None:  6719861
Info Table:
Name of Issuer:  Samsara
Title of Class:  COM CL A
CUSIP:  79589L-10-6
Value:  72,044,437
Shrs or Prn Amt:
Ssh Prnamt:  3653369
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1580143
Shared:  0
None:  2073226
Info Table:
Name of Issuer:  Samsara
Title of Class:  COM CL A
CUSIP:  79589L-10-6
Value:  44,781,083
Shrs or Prn Amt:
Ssh Prnamt:  2270846
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1955534
Shared:  0
None:  315312
Info Table:
Name of Issuer:  Sana Biotechnology Inc
Title of Class:  COM
CUSIP:  799566-10-4
Value:  5,319,139
Shrs or Prn Amt:
Ssh Prnamt:  1626648
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1626648
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sana Biotechnology Inc
Title of Class:  COM
CUSIP:  799566-10-4
Value:  9,044,127
Shrs or Prn Amt:
Ssh Prnamt:  2765788
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2765788
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sana Biotechnology Inc
Title of Class:  COM
CUSIP:  799566-10-4
Value:  615,483
Shrs or Prn Amt:
Ssh Prnamt:  188221
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  188221
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sana Biotechnology Inc
Title of Class:  COM
CUSIP:  799566-10-4
Value:  20,588,809
Shrs or Prn Amt:
Ssh Prnamt:  6296272
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  6296272
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sangamo Biosciences
Title of Class:  COM
CUSIP:  800677-10-6
Value:  4,418
Shrs or Prn Amt:
Ssh Prnamt:  2510
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2510
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sarepta Therapeutics Inc
Title of Class:  COM
CUSIP:  803607-10-0
Value:  31,839
Shrs or Prn Amt:
Ssh Prnamt:  231
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  231
Shared:  0
None:  0
Info Table:
Name of Issuer:  Schrodinger
Title of Class:  COM
CUSIP:  80810D-10-3
Value:  13,524,194
Shrs or Prn Amt:
Ssh Prnamt:  513642
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  513642
Shared:  0
None:  0
Info Table:
Name of Issuer:  Schrodinger
Title of Class:  COM
CUSIP:  80810D-10-3
Value:  24,238,160
Shrs or Prn Amt:
Ssh Prnamt:  920553
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  267012
Shared:  0
None:  653541
Info Table:
Name of Issuer:  Schrodinger
Title of Class:  COM
CUSIP:  80810D-10-3
Value:  13,020,317
Shrs or Prn Amt:
Ssh Prnamt:  494505
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  494505
Shared:  0
None:  0
Info Table:
Name of Issuer:  Schrodinger
Title of Class:  COM
CUSIP:  80810D-10-3
Value:  9,377,456
Shrs or Prn Amt:
Ssh Prnamt:  356151
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  356151
Shared:  0
None:  0
Info Table:
Name of Issuer:  Scilex Hdg
Title of Class:  COM
CUSIP:  80880W-10-6
Value:  4,289
Shrs or Prn Amt:
Ssh Prnamt:  523
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  523
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sea Ltd ADR
Title of Class:  ADR
CUSIP:  81141R-10-0
Value:  2,684,694
Shrs or Prn Amt:
Ssh Prnamt:  31019
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  31019
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sea Ltd ADR
Title of Class:  ADR
CUSIP:  81141R-10-0
Value:  124,285,281
Shrs or Prn Amt:
Ssh Prnamt:  1435994
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  955353
Shared:  0
None:  480641
Info Table:
Name of Issuer:  Sea Ltd ADR
Title of Class:  ADR
CUSIP:  81141R-10-0
Value:  1,238,770,070
Shrs or Prn Amt:
Ssh Prnamt:  14312768
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  9616207
Shared:  0
None:  4696561
Info Table:
Name of Issuer:  Sea Ltd ADR
Title of Class:  ADR
CUSIP:  81141R-10-0
Value:  237,058,979
Shrs or Prn Amt:
Ssh Prnamt:  2738983
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2738983
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sea Ltd ADR
Title of Class:  ADR
CUSIP:  81141R-10-0
Value:  300,557,165
Shrs or Prn Amt:
Ssh Prnamt:  3472642
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2066936
Shared:  0
None:  1405706
Info Table:
Name of Issuer:  Seagen Inc
Title of Class:  COM
CUSIP:  81181C-10-4
Value:  25,916
Shrs or Prn Amt:
Ssh Prnamt:  128
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  128
Shared:  0
None:  0
Info Table:
Name of Issuer:  Seer
Title of Class:  COM CL A
CUSIP:  81578P-10-6
Value:  861
Shrs or Prn Amt:
Ssh Prnamt:  223
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  223
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sei Investments Co
Title of Class:  COM
CUSIP:  784117-10-3
Value:  29,235
Shrs or Prn Amt:
Ssh Prnamt:  508
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  508
Shared:  0
None:  0
Info Table:
Name of Issuer:  Service Corp.Intl.
Title of Class:  COM
CUSIP:  817565-10-4
Value:  382,068,361
Shrs or Prn Amt:
Ssh Prnamt:  5554934
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4924010
Shared:  0
None:  630924
Info Table:
Name of Issuer:  Service Corp.Intl.
Title of Class:  COM
CUSIP:  817565-10-4
Value:  123,591,745
Shrs or Prn Amt:
Ssh Prnamt:  1796914
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1796914
Shared:  0
None:  0
Info Table:
Name of Issuer:  Service Corp.Intl.
Title of Class:  COM
CUSIP:  817565-10-4
Value:  97,972,639
Shrs or Prn Amt:
Ssh Prnamt:  1424435
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  779499
Shared:  0
None:  644936
Info Table:
Name of Issuer:  Service Corp.Intl.
Title of Class:  COM
CUSIP:  817565-10-4
Value:  444,217,762
Shrs or Prn Amt:
Ssh Prnamt:  6458531
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  4246664
Shared:  0
None:  2211867
Info Table:
Name of Issuer:  Sherwin-Williams Co
Title of Class:  COM
CUSIP:  824348-10-6
Value:  9,596,330
Shrs or Prn Amt:
Ssh Prnamt:  42694
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  42694
Shared:  0
None:  0
Info Table:
Name of Issuer:  ShockWave Medical Inc
Title of Class:  COM
CUSIP:  82489T-10-4
Value:  12,041,871
Shrs or Prn Amt:
Ssh Prnamt:  55536
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  55536
Shared:  0
None:  0
Info Table:
Name of Issuer:  ShockWave Medical Inc
Title of Class:  COM
CUSIP:  82489T-10-4
Value:  31,524,263
Shrs or Prn Amt:
Ssh Prnamt:  145387
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  92512
Shared:  0
None:  52875
Info Table:
Name of Issuer:  ShockWave Medical Inc
Title of Class:  COM
CUSIP:  82489T-10-4
Value:  20,061,112
Shrs or Prn Amt:
Ssh Prnamt:  92520
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  92520
Shared:  0
None:  0
Info Table:
Name of Issuer:  ShockWave Medical Inc
Title of Class:  COM
CUSIP:  82489T-10-4
Value:  11,618,619
Shrs or Prn Amt:
Ssh Prnamt:  53584
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  53584
Shared:  0
None:  0
Info Table:
Name of Issuer:  Shopify 'A'
Title of Class:  CL A
CUSIP:  82509L-10-7
Value:  319,114,959
Shrs or Prn Amt:
Ssh Prnamt:  6656549
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  5294103
Shared:  0
None:  1362446
Info Table:
Name of Issuer:  Shopify 'A'
Title of Class:  CL A
CUSIP:  82509L-10-7
Value:  1,805,857,948
Shrs or Prn Amt:
Ssh Prnamt:  37669127
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  25792967
Shared:  0
None:  11876160
Info Table:
Name of Issuer:  Shopify 'A'
Title of Class:  CL A
CUSIP:  82509L-10-7
Value:  669,786,759
Shrs or Prn Amt:
Ssh Prnamt:  13971355
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  13971355
Shared:  0
None:  0
Info Table:
Name of Issuer:  Shopify 'A'
Title of Class:  CL A
CUSIP:  82509L-10-7
Value:  4,315
Shrs or Prn Amt:
Ssh Prnamt:  90
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  90
Shared:  0
None:  0
Info Table:
Name of Issuer:  Shopify 'A'
Title of Class:  CL A
CUSIP:  82509L-10-7
Value:  608,551,175
Shrs or Prn Amt:
Ssh Prnamt:  12694017
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  8618452
Shared:  0
None:  4075565
Info Table:
Name of Issuer:  Shopify Inc
Title of Class:  COM
CUSIP:  82509L-10-7
Value:  106,200
Shrs or Prn Amt:
Ssh Prnamt:  2218
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2218
Shared:  0
None:  0
Info Table:
Name of Issuer:  Shopify Inc
Title of Class:  COM
CUSIP:  82509L-10-7
Value:  5,883,066
Shrs or Prn Amt:
Ssh Prnamt:  122868
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  122868
Shared:  0
None:  0
Info Table:
Name of Issuer:  Silk Road Medical
Title of Class:  COM
CUSIP:  82710M-10-0
Value:  11,074
Shrs or Prn Amt:
Ssh Prnamt:  283
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  283
Shared:  0
None:  0
Info Table:
Name of Issuer:  SiteOne Landscape Supply
Title of Class:  COM
CUSIP:  82982L-10-3
Value:  30,150,682
Shrs or Prn Amt:
Ssh Prnamt:  220287
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  120592
Shared:  0
None:  99695
Info Table:
Name of Issuer:  SiteOne Landscape Supply
Title of Class:  COM
CUSIP:  82982L-10-3
Value:  112,094,340
Shrs or Prn Amt:
Ssh Prnamt:  818984
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  722099
Shared:  0
None:  96885
Info Table:
Name of Issuer:  SiteOne Landscape Supply
Title of Class:  COM
CUSIP:  82982L-10-3
Value:  37,416,152
Shrs or Prn Amt:
Ssh Prnamt:  273370
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  273370
Shared:  0
None:  0
Info Table:
Name of Issuer:  SiteOne Landscape Supply
Title of Class:  COM
CUSIP:  82982L-10-3
Value:  135,107,251
Shrs or Prn Amt:
Ssh Prnamt:  987121
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  638189
Shared:  0
None:  348932
Info Table:
Name of Issuer:  Sixth Street Specialty Lending
Title of Class:  COM
CUSIP:  83012A-10-9
Value:  1,454,850
Shrs or Prn Amt:
Ssh Prnamt:  79500
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  79500
Shared:  0
None:  0
Info Table:
Name of Issuer:  Smartsheet
Title of Class:  COM
CUSIP:  83200N-10-3
Value:  16,826
Shrs or Prn Amt:
Ssh Prnamt:  352
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  352
Shared:  0
None:  0
Info Table:
Name of Issuer:  Snap Inc
Title of Class:  CL A
CUSIP:  83304A-10-6
Value:  43,253,034
Shrs or Prn Amt:
Ssh Prnamt:  3858433
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3858433
Shared:  0
None:  0
Info Table:
Name of Issuer:  Snap Inc
Title of Class:  CL A
CUSIP:  83304A-10-6
Value:  66,196,788
Shrs or Prn Amt:
Ssh Prnamt:  5905155
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  5847278
Shared:  0
None:  57877
Info Table:
Name of Issuer:  Snap Inc
Title of Class:  CL A
CUSIP:  83304A-10-6
Value:  2,770,249
Shrs or Prn Amt:
Ssh Prnamt:  247123
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  247123
Shared:  0
None:  0
Info Table:
Name of Issuer:  Snap Inc
Title of Class:  CL A
CUSIP:  83304A-10-6
Value:  9,789,491
Shrs or Prn Amt:
Ssh Prnamt:  873282
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  873282
Shared:  0
None:  0
Info Table:
Name of Issuer:  Snap On
Title of Class:  COM
CUSIP:  833034-10-1
Value:  21,233
Shrs or Prn Amt:
Ssh Prnamt:  86
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  86
Shared:  0
None:  0
Info Table:
Name of Issuer:  Snowflake Inc
Title of Class:  COM
CUSIP:  833445-10-9
Value:  241,655,787
Shrs or Prn Amt:
Ssh Prnamt:  1566244
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1503510
Shared:  0
None:  62734
Info Table:
Name of Issuer:  Snowflake Inc
Title of Class:  COM
CUSIP:  833445-10-9
Value:  26,093,988
Shrs or Prn Amt:
Ssh Prnamt:  169123
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  113168
Shared:  0
None:  55955
Info Table:
Name of Issuer:  Snowflake Inc
Title of Class:  COM
CUSIP:  833445-10-9
Value:  307,598,407
Shrs or Prn Amt:
Ssh Prnamt:  1993638
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1797871
Shared:  0
None:  195767
Info Table:
Name of Issuer:  Snowflake Inc
Title of Class:  COM
CUSIP:  833445-10-9
Value:  129,668,402
Shrs or Prn Amt:
Ssh Prnamt:  840420
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  840420
Shared:  0
None:  0
Info Table:
Name of Issuer:  Solaredge Technologies Inc
Title of Class:  COM
CUSIP:  83417M-10-4
Value:  57,143
Shrs or Prn Amt:
Ssh Prnamt:  188
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  188
Shared:  0
None:  0
Info Table:
Name of Issuer:  Solaredge Technologies Inc
Title of Class:  COM
CUSIP:  83417M-10-4
Value:  348,631
Shrs or Prn Amt:
Ssh Prnamt:  1147
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1147
Shared:  0
None:  0
Info Table:
Name of Issuer:  Solaredge Technologies Inc
Title of Class:  COM
CUSIP:  83417M-10-4
Value:  274,399,677
Shrs or Prn Amt:
Ssh Prnamt:  902779
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  758022
Shared:  0
None:  144757
Info Table:
Name of Issuer:  Solaredge Technologies Inc
Title of Class:  COM
CUSIP:  83417M-10-4
Value:  8,303,002
Shrs or Prn Amt:
Ssh Prnamt:  27317
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  0
Shared:  0
None:  27317
Info Table:
Name of Issuer:  Sorrento Therapeutics
Title of Class:  COM
CUSIP:  83587F-20-2
Value:  1,336
Shrs or Prn Amt:
Ssh Prnamt:  3711
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  3711
Shared:  0
None:  0
Info Table:
Name of Issuer:  Spire Global Inc
Title of Class:  COM CL A
CUSIP:  848560-10-8
Value:  578,518
Shrs or Prn Amt:
Ssh Prnamt:  866045
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  866045
Shared:  0
None:  0
Info Table:
Name of Issuer:  Splunk Inc
Title of Class:  COM
CUSIP:  848637-10-4
Value:  4,607,609
Shrs or Prn Amt:
Ssh Prnamt:  48056
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  48056
Shared:  0
None:  0
Info Table:
Name of Issuer:  Splunk Inc
Title of Class:  COM
CUSIP:  848637-10-4
Value:  12,781,092
Shrs or Prn Amt:
Ssh Prnamt:  133303
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  38049
Shared:  0
None:  95254
Info Table:
Name of Issuer:  Splunk Inc
Title of Class:  COM
CUSIP:  848637-10-4
Value:  3,628,099
Shrs or Prn Amt:
Ssh Prnamt:  37840
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  37840
Shared:  0
None:  0
Info Table:
Name of Issuer:  Splunk Inc
Title of Class:  COM
CUSIP:  848637-10-4
Value:  7,083,998
Shrs or Prn Amt:
Ssh Prnamt:  73884
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  73884
Shared:  0
None:  0
Info Table:
Name of Issuer:  Spotify Technology SA
Title of Class:  SHS
CUSIP:  L8681T-10-2
Value:  140,512,120
Shrs or Prn Amt:
Ssh Prnamt:  1051580
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1051580
Shared:  0
None:  0
Info Table:
Name of Issuer:  Spotify Technology SA
Title of Class:  SHS
CUSIP:  L8681T-10-2
Value:  2,952,473,934
Shrs or Prn Amt:
Ssh Prnamt:  22096048
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  16714202
Shared:  0
None:  5381846
Info Table:
Name of Issuer:  Spotify Technology SA
Title of Class:  SHS
CUSIP:  L8681T-10-2
Value:  114,741,766
Shrs or Prn Amt:
Ssh Prnamt:  858717
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  694077
Shared:  0
None:  164640
Info Table:
Name of Issuer:  Spotify Technology SA
Title of Class:  SHS
CUSIP:  L8681T-10-2
Value:  3,608
Shrs or Prn Amt:
Ssh Prnamt:  27
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  27
Shared:  0
None:  0
Info Table:
Name of Issuer:  Spotify Technology SA
Title of Class:  SHS
CUSIP:  L8681T-10-2
Value:  466,107,849
Shrs or Prn Amt:
Ssh Prnamt:  3488309
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2648242
Shared:  0
None:  840067
Info Table:
Name of Issuer:  Sprout Social
Title of Class:  COM
CUSIP:  85209W-10-9
Value:  19,547,229
Shrs or Prn Amt:
Ssh Prnamt:  321078
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  321078
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sprout Social
Title of Class:  COM
CUSIP:  85209W-10-9
Value:  18,274,776
Shrs or Prn Amt:
Ssh Prnamt:  300177
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  87965
Shared:  0
None:  212212
Info Table:
Name of Issuer:  Sprout Social
Title of Class:  COM
CUSIP:  85209W-10-9
Value:  7,833,978
Shrs or Prn Amt:
Ssh Prnamt:  128679
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  128679
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sprout Social
Title of Class:  COM
CUSIP:  85209W-10-9
Value:  14,968,566
Shrs or Prn Amt:
Ssh Prnamt:  245870
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  245870
Shared:  0
None:  0
Info Table:
Name of Issuer:  Staar Surgical
Title of Class:  COM PAR $0.01
CUSIP:  852312-30-5
Value:  102,985,016
Shrs or Prn Amt:
Ssh Prnamt:  1610399
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  995254
Shared:  0
None:  615145
Info Table:
Name of Issuer:  Staar Surgical
Title of Class:  COM PAR $0.01
CUSIP:  852312-30-5
Value:  92,402,122
Shrs or Prn Amt:
Ssh Prnamt:  1444912
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1444912
Shared:  0
None:  0
Info Table:
Name of Issuer:  Staar Surgical
Title of Class:  COM PAR $0.01
CUSIP:  852312-30-5
Value:  38,850,520
Shrs or Prn Amt:
Ssh Prnamt:  607514
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  485974
Shared:  0
None:  121540
Info Table:
Name of Issuer:  Staar Surgical
Title of Class:  COM PAR $0.01
CUSIP:  852312-30-5
Value:  93,463,948
Shrs or Prn Amt:
Ssh Prnamt:  1461516
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1130125
Shared:  0
None:  331391
Info Table:
Name of Issuer:  Starbucks Corp
Title of Class:  COM
CUSIP:  855244-10-9
Value:  10,247,329
Shrs or Prn Amt:
Ssh Prnamt:  98409
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  85127
Shared:  0
None:  13282
Info Table:
Name of Issuer:  Starbucks Corp
Title of Class:  COM
CUSIP:  855244-10-9
Value:  23,688,950
Shrs or Prn Amt:
Ssh Prnamt:  227494
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  186950
Shared:  0
None:  40544
Info Table:
Name of Issuer:  Starbucks Corp
Title of Class:  COM
CUSIP:  855244-10-9
Value:  41,273,800
Shrs or Prn Amt:
Ssh Prnamt:  396368
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  396368
Shared:  0
None:  0
Info Table:
Name of Issuer:  Starbucks Corp
Title of Class:  COM
CUSIP:  855244-10-9
Value:  24,327,996
Shrs or Prn Amt:
Ssh Prnamt:  233631
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  233631
Shared:  0
None:  0
Info Table:
Name of Issuer:  Stitch Fix
Title of Class:  COM CL A
CUSIP:  860897-10-7
Value:  11,799
Shrs or Prn Amt:
Ssh Prnamt:  2309
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2309
Shared:  0
None:  0
Info Table:
Name of Issuer:  Stitch Fix
Title of Class:  COM CL A
CUSIP:  860897-10-7
Value:  165,058
Shrs or Prn Amt:
Ssh Prnamt:  32301
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  32301
Shared:  0
None:  0
Info Table:
Name of Issuer:  Stratasys
Title of Class:  SHS
CUSIP:  M85548-10-1
Value:  2,256,973
Shrs or Prn Amt:
Ssh Prnamt:  136538
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  136538
Shared:  0
None:  0
Info Table:
Name of Issuer:  Stratasys
Title of Class:  SHS
CUSIP:  M85548-10-1
Value:  5,224,505
Shrs or Prn Amt:
Ssh Prnamt:  316062
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  94180
Shared:  0
None:  221882
Info Table:
Name of Issuer:  Stratasys
Title of Class:  SHS
CUSIP:  M85548-10-1
Value:  3,740,739
Shrs or Prn Amt:
Ssh Prnamt:  226300
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  226300
Shared:  0
None:  0
Info Table:
Name of Issuer:  Stratasys
Title of Class:  SHS
CUSIP:  M85548-10-1
Value:  2,390,238
Shrs or Prn Amt:
Ssh Prnamt:  144600
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  144600
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sumo Logic
Title of Class:  COM
CUSIP:  86646P-10-3
Value:  11,333
Shrs or Prn Amt:
Ssh Prnamt:  946
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  946
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sunpower Corp
Title of Class:  COM
CUSIP:  867652-40-6
Value:  16,746
Shrs or Prn Amt:
Ssh Prnamt:  1210
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1210
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sutro Biopharma
Title of Class:  COM
CUSIP:  869367-10-2
Value:  22,952
Shrs or Prn Amt:
Ssh Prnamt:  4968
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4968
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sutro Biopharma
Title of Class:  COM
CUSIP:  869367-10-2
Value:  4,816,017
Shrs or Prn Amt:
Ssh Prnamt:  1042428
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1042428
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sutro Biopharma
Title of Class:  COM
CUSIP:  869367-10-2
Value:  321,238
Shrs or Prn Amt:
Ssh Prnamt:  69532
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  69532
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sutro Biopharma
Title of Class:  COM
CUSIP:  869367-10-2
Value:  3,468,354
Shrs or Prn Amt:
Ssh Prnamt:  750726
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  750726
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sweetgreen
Title of Class:  COM CL A
CUSIP:  87043Q-10-8
Value:  14,913,781
Shrs or Prn Amt:
Ssh Prnamt:  1902268
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1902268
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sweetgreen
Title of Class:  COM CL A
CUSIP:  87043Q-10-8
Value:  22,302,315
Shrs or Prn Amt:
Ssh Prnamt:  2844683
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2817068
Shared:  0
None:  27615
Info Table:
Name of Issuer:  Sweetgreen
Title of Class:  COM CL A
CUSIP:  87043Q-10-8
Value:  942,674
Shrs or Prn Amt:
Ssh Prnamt:  120239
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  120239
Shared:  0
None:  0
Info Table:
Name of Issuer:  Sweetgreen
Title of Class:  COM CL A
CUSIP:  87043Q-10-8
Value:  2,962,540
Shrs or Prn Amt:
Ssh Prnamt:  377875
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  377875
Shared:  0
None:  0
Info Table:
Name of Issuer:  T. Rowe Price
Title of Class:  COM
CUSIP:  74144T-10-8
Value:  4,052,433
Shrs or Prn Amt:
Ssh Prnamt:  35894
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  35894
Shared:  0
None:  0
Info Table:
Name of Issuer:  T. Rowe Price
Title of Class:  COM
CUSIP:  74144T-10-8
Value:  183,350
Shrs or Prn Amt:
Ssh Prnamt:  1624
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  0
Shared:  0
None:  1624
Info Table:
Name of Issuer:  T. Rowe Price
Title of Class:  COM
CUSIP:  74144T-10-8
Value:  19,396,107
Shrs or Prn Amt:
Ssh Prnamt:  171799
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  171799
Shared:  0
None:  0
Info Table:
Name of Issuer:  T. Rowe Price
Title of Class:  COM
CUSIP:  74144T-10-8
Value:  11,508,349
Shrs or Prn Amt:
Ssh Prnamt:  101934
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  101934
Shared:  0
None:  0
Info Table:
Name of Issuer:  TJX Companies
Title of Class:  COM
CUSIP:  872540-10-9
Value:  8,418,293
Shrs or Prn Amt:
Ssh Prnamt:  107431
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  107431
Shared:  0
None:  0
Info Table:
Name of Issuer:  TJX Companies
Title of Class:  COM
CUSIP:  872540-10-9
Value:  32,833
Shrs or Prn Amt:
Ssh Prnamt:  419
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  419
Shared:  0
None:  0
Info Table:
Name of Issuer:  TJX Companies
Title of Class:  COM
CUSIP:  872540-10-9
Value:  8,318,854
Shrs or Prn Amt:
Ssh Prnamt:  106162
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  106162
Shared:  0
None:  0
Info Table:
Name of Issuer:  TSMC ADR
Title of Class:  SPONSORED ADR
CUSIP:  874039-10-0
Value:  602,832,947
Shrs or Prn Amt:
Ssh Prnamt:  6480681
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  4987185
Shared:  0
None:  1493496
Info Table:
Name of Issuer:  TSMC ADR
Title of Class:  SPONSORED ADR
CUSIP:  874039-10-0
Value:  14,418
Shrs or Prn Amt:
Ssh Prnamt:  155
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  155
Shared:  0
None:  0
Info Table:
Name of Issuer:  TSMC ADR
Title of Class:  SPONSORED ADR
CUSIP:  874039-10-0
Value:  14,883
Shrs or Prn Amt:
Ssh Prnamt:  160
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  160
Shared:  0
None:  0
Info Table:
Name of Issuer:  TSMC ADR
Title of Class:  SPONSORED ADR
CUSIP:  874039-10-0
Value:  56,868,707
Shrs or Prn Amt:
Ssh Prnamt:  611360
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  485596
Shared:  0
None:  125764
Info Table:
Name of Issuer:  Tabula Rasa HealthCare Inc
Title of Class:  COM
CUSIP:  873379-10-1
Value:  164,620
Shrs or Prn Amt:
Ssh Prnamt:  29449
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  29449
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tabula Rasa HealthCare Inc
Title of Class:  COM
CUSIP:  873379-10-1
Value:  11,627
Shrs or Prn Amt:
Ssh Prnamt:  2080
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2080
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tabula Rasa HealthCare Inc
Title of Class:  COM
CUSIP:  873379-10-1
Value:  3,136,968
Shrs or Prn Amt:
Ssh Prnamt:  561175
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  561175
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tabula Rasa HealthCare Inc
Title of Class:  COM
CUSIP:  873379-10-1
Value:  1,333,629
Shrs or Prn Amt:
Ssh Prnamt:  238574
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  238574
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tandem Diabetes Care
Title of Class:  COM NEW
CUSIP:  875372-20-3
Value:  4,184,576
Shrs or Prn Amt:
Ssh Prnamt:  103043
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  103043
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tandem Diabetes Care
Title of Class:  COM NEW
CUSIP:  875372-20-3
Value:  30,498
Shrs or Prn Amt:
Ssh Prnamt:  751
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  751
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tandem Diabetes Care
Title of Class:  COM NEW
CUSIP:  875372-20-3
Value:  437,451
Shrs or Prn Amt:
Ssh Prnamt:  10772
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  10772
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tandem Diabetes Care
Title of Class:  COM NEW
CUSIP:  875372-20-3
Value:  6,025,590
Shrs or Prn Amt:
Ssh Prnamt:  148377
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  148377
Shared:  0
None:  0
Info Table:
Name of Issuer:  Target Corp
Title of Class:  COM
CUSIP:  87612E-10-6
Value:  18,551
Shrs or Prn Amt:
Ssh Prnamt:  112
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  112
Shared:  0
None:  0
Info Table:
Name of Issuer:  Teladoc
Title of Class:  COM
CUSIP:  87918A-10-5
Value:  44,399,230
Shrs or Prn Amt:
Ssh Prnamt:  1714256
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1714256
Shared:  0
None:  0
Info Table:
Name of Issuer:  Teladoc
Title of Class:  COM
CUSIP:  87918A-10-5
Value:  30,599,011
Shrs or Prn Amt:
Ssh Prnamt:  1181429
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  628758
Shared:  0
None:  552671
Info Table:
Name of Issuer:  Teladoc
Title of Class:  COM
CUSIP:  87918A-10-5
Value:  15,672,375
Shrs or Prn Amt:
Ssh Prnamt:  605111
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  389449
Shared:  0
None:  215662
Info Table:
Name of Issuer:  Teladoc
Title of Class:  COM
CUSIP:  87918A-10-5
Value:  34,345,601
Shrs or Prn Amt:
Ssh Prnamt:  1326085
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1104853
Shared:  0
None:  221232
Info Table:
Name of Issuer:  Telus Corp
Title of Class:  COM
CUSIP:  87971M-10-3
Value:  11,439
Shrs or Prn Amt:
Ssh Prnamt:  576
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  576
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tencent Music Entertainment ADR
Title of Class:  SPONSORED ADS
CUSIP:  88034P-10-9
Value:  7,362,452
Shrs or Prn Amt:
Ssh Prnamt:  889185
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  889185
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tencent Music Entertainment ADR
Title of Class:  SPONSORED ADS
CUSIP:  88034P-10-9
Value:  4,343,746
Shrs or Prn Amt:
Ssh Prnamt:  524607
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  43926
Shared:  0
None:  480681
Info Table:
Name of Issuer:  Tencent Music Entertainment ADR
Title of Class:  SPONSORED ADS
CUSIP:  88034P-10-9
Value:  225,834,094
Shrs or Prn Amt:
Ssh Prnamt:  27274649
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  19160307
Shared:  0
None:  8114342
Info Table:
Name of Issuer:  Tencent Music Entertainment ADR
Title of Class:  SPONSORED ADS
CUSIP:  88034P-10-9
Value:  4,513
Shrs or Prn Amt:
Ssh Prnamt:  545
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  545
Shared:  0
None:  0
Info Table:
Name of Issuer:  Teradyne
Title of Class:  COM
CUSIP:  880770-10-2
Value:  64,878,200
Shrs or Prn Amt:
Ssh Prnamt:  603462
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  603462
Shared:  0
None:  0
Info Table:
Name of Issuer:  Teradyne
Title of Class:  COM
CUSIP:  880770-10-2
Value:  227,536,099
Shrs or Prn Amt:
Ssh Prnamt:  2116418
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1349343
Shared:  0
None:  767075
Info Table:
Name of Issuer:  Teradyne
Title of Class:  COM
CUSIP:  880770-10-2
Value:  51,487,614
Shrs or Prn Amt:
Ssh Prnamt:  478910
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  265766
Shared:  0
None:  213144
Info Table:
Name of Issuer:  Teradyne
Title of Class:  COM
CUSIP:  880770-10-2
Value:  188,938,827
Shrs or Prn Amt:
Ssh Prnamt:  1757407
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1548315
Shared:  0
None:  209092
Info Table:
Name of Issuer:  Tesla Inc
Title of Class:  COM
CUSIP:  88160R-10-1
Value:  659,060,173
Shrs or Prn Amt:
Ssh Prnamt:  3176806
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  3176806
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tesla Inc
Title of Class:  COM
CUSIP:  88160R-10-1
Value:  2,825,946,679
Shrs or Prn Amt:
Ssh Prnamt:  13621646
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  9875676
Shared:  0
None:  3745970
Info Table:
Name of Issuer:  Tesla Inc
Title of Class:  COM
CUSIP:  88160R-10-1
Value:  390,515,235
Shrs or Prn Amt:
Ssh Prnamt:  1882364
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  1511963
Shared:  0
None:  370401
Info Table:
Name of Issuer:  Tesla Inc
Title of Class:  COM
CUSIP:  88160R-10-1
Value:  1,529,740,956
Shrs or Prn Amt:
Ssh Prnamt:  7373667
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5888761
Shared:  0
None:  1484906
Info Table:
Name of Issuer:  Texas Instruments
Title of Class:  COM
CUSIP:  882508-10-4
Value:  15,853,260
Shrs or Prn Amt:
Ssh Prnamt:  85228
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  85228
Shared:  0
None:  0
Info Table:
Name of Issuer:  Texas Instruments
Title of Class:  COM
CUSIP:  882508-10-4
Value:  17,193,090
Shrs or Prn Amt:
Ssh Prnamt:  92431
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  66417
Shared:  0
None:  26014
Info Table:
Name of Issuer:  Texas Instruments
Title of Class:  COM
CUSIP:  882508-10-4
Value:  8,466,431
Shrs or Prn Amt:
Ssh Prnamt:  45516
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  45516
Shared:  0
None:  0
Info Table:
Name of Issuer:  Texas Instruments
Title of Class:  COM
CUSIP:  882508-10-4
Value:  4,825,285
Shrs or Prn Amt:
Ssh Prnamt:  25941
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  16820
Shared:  0
None:  9121
Info Table:
Name of Issuer:  The Trade Desk
Title of Class:  COM CL A
CUSIP:  88339J-10-5
Value:  561,600,007
Shrs or Prn Amt:
Ssh Prnamt:  9220161
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  9220161
Shared:  0
None:  0
Info Table:
Name of Issuer:  The Trade Desk
Title of Class:  COM CL A
CUSIP:  88339J-10-5
Value:  211,779,014
Shrs or Prn Amt:
Ssh Prnamt:  3476917
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  2781413
Shared:  0
None:  695504
Info Table:
Name of Issuer:  The Trade Desk
Title of Class:  COM CL A
CUSIP:  88339J-10-5
Value:  1,495,249,379
Shrs or Prn Amt:
Ssh Prnamt:  24548504
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  17260976
Shared:  0
None:  7287528
Info Table:
Name of Issuer:  The Trade Desk
Title of Class:  COM CL A
CUSIP:  88339J-10-5
Value:  522,946,155
Shrs or Prn Amt:
Ssh Prnamt:  8585555
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5289279
Shared:  0
None:  3296276
Info Table:
Name of Issuer:  Thermo Fisher Scientific
Title of Class:  COM
CUSIP:  883556-10-2
Value:  78,571,335
Shrs or Prn Amt:
Ssh Prnamt:  136321
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  136321
Shared:  0
None:  0
Info Table:
Name of Issuer:  Thermo Fisher Scientific
Title of Class:  COM
CUSIP:  883556-10-2
Value:  252,180,895
Shrs or Prn Amt:
Ssh Prnamt:  437533
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  390885
Shared:  0
None:  46648
Info Table:
Name of Issuer:  Thermo Fisher Scientific
Title of Class:  COM
CUSIP:  883556-10-2
Value:  296,010,952
Shrs or Prn Amt:
Ssh Prnamt:  513578
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  341921
Shared:  0
None:  171657
Info Table:
Name of Issuer:  Thermo Fisher Scientific
Title of Class:  COM
CUSIP:  883556-10-2
Value:  61,300,984
Shrs or Prn Amt:
Ssh Prnamt:  106357
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  58208
Shared:  0
None:  48149
Info Table:
Name of Issuer:  Toro Co
Title of Class:  COM
CUSIP:  891092-10-8
Value:  32,459
Shrs or Prn Amt:
Ssh Prnamt:  292
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  292
Shared:  0
None:  0
Info Table:
Name of Issuer:  Tractor Supply Co
Title of Class:  COM
CUSIP:  892356-10-6
Value:  41,602
Shrs or Prn Amt:
Ssh Prnamt:  177
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  177
Shared:  0
None:  0
Info Table:
Name of Issuer:  TransMedics Group
Title of Class:  COM
CUSIP:  89377M-10-9
Value:  2,471,751
Shrs or Prn Amt:
Ssh Prnamt:  32639
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  32639
Shared:  0
None:  0
Info Table:
Name of Issuer:  TransMedics Group
Title of Class:  COM
CUSIP:  89377M-10-9
Value:  173,043
Shrs or Prn Amt:
Ssh Prnamt:  2285
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2285
Shared:  0
None:  0
Info Table:
Name of Issuer:  TransMedics Group
Title of Class:  COM
CUSIP:  89377M-10-9
Value:  8,428,825
Shrs or Prn Amt:
Ssh Prnamt:  111301
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  111301
Shared:  0
None:  0
Info Table:
Name of Issuer:  TransMedics Group
Title of Class:  COM
CUSIP:  89377M-10-9
Value:  8,083,950
Shrs or Prn Amt:
Ssh Prnamt:  106747
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  106747
Shared:  0
None:  0
Info Table:
Name of Issuer:  Trupanion
Title of Class:  COM
CUSIP:  898202-10-6
Value:  7,278,433
Shrs or Prn Amt:
Ssh Prnamt:  169700
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  169700
Shared:  0
None:  0
Info Table:
Name of Issuer:  Trupanion
Title of Class:  COM
CUSIP:  898202-10-6
Value:  7,934,650
Shrs or Prn Amt:
Ssh Prnamt:  185000
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  185000
Shared:  0
None:  0
Info Table:
Name of Issuer:  Trupanion
Title of Class:  COM
CUSIP:  898202-10-6
Value:  13,841,032
Shrs or Prn Amt:
Ssh Prnamt:  322710
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  93427
Shared:  0
None:  229283
Info Table:
Name of Issuer:  Trupanion
Title of Class:  COM
CUSIP:  898202-10-6
Value:  5,629,484
Shrs or Prn Amt:
Ssh Prnamt:  131254
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  131254
Shared:  0
None:  0
Info Table:
Name of Issuer:  TuSimple Hdgs
Title of Class:  CL A
CUSIP:  90089L-10-8
Value:  513
Shrs or Prn Amt:
Ssh Prnamt:  349
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  349
Shared:  0
None:  0
Info Table:
Name of Issuer:  Twilio Inc
Title of Class:  CL A
CUSIP:  90138F-10-2
Value:  110,050,172
Shrs or Prn Amt:
Ssh Prnamt:  1651661
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1651661
Shared:  0
None:  0
Info Table:
Name of Issuer:  Twilio Inc
Title of Class:  CL A
CUSIP:  90138F-10-2
Value:  163,504,290
Shrs or Prn Amt:
Ssh Prnamt:  2453914
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2401668
Shared:  0
None:  52246
Info Table:
Name of Issuer:  Twilio Inc
Title of Class:  CL A
CUSIP:  90138F-10-2
Value:  8,536,236
Shrs or Prn Amt:
Ssh Prnamt:  128114
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  117758
Shared:  0
None:  10356
Info Table:
Name of Issuer:  Twilio Inc
Title of Class:  CL A
CUSIP:  90138F-10-2
Value:  22,852,957
Shrs or Prn Amt:
Ssh Prnamt:  342983
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  342983
Shared:  0
None:  0
Info Table:
Name of Issuer:  Twist Bioscience Corp
Title of Class:  COM
CUSIP:  90184D-10-0
Value:  4,416,932
Shrs or Prn Amt:
Ssh Prnamt:  292900
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  292900
Shared:  0
None:  0
Info Table:
Name of Issuer:  Twist Bioscience Corp
Title of Class:  COM
CUSIP:  90184D-10-0
Value:  4,116,840
Shrs or Prn Amt:
Ssh Prnamt:  273000
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  273000
Shared:  0
None:  0
Info Table:
Name of Issuer:  Twist Bioscience Corp
Title of Class:  COM
CUSIP:  90184D-10-0
Value:  2,176,059
Shrs or Prn Amt:
Ssh Prnamt:  144301
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  144301
Shared:  0
None:  0
Info Table:
Name of Issuer:  Twist Bioscience Corp
Title of Class:  COM
CUSIP:  90184D-10-0
Value:  5,577,021
Shrs or Prn Amt:
Ssh Prnamt:  369829
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  107146
Shared:  0
None:  262683
Info Table:
Name of Issuer:  Ultragenyx
Title of Class:  COM
CUSIP:  90400D-10-8
Value:  4,612
Shrs or Prn Amt:
Ssh Prnamt:  115
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  115
Shared:  0
None:  0
Info Table:
Name of Issuer:  United Parcel Service
Title of Class:  CL B
CUSIP:  911312-10-6
Value:  9,728,599
Shrs or Prn Amt:
Ssh Prnamt:  50150
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  46836
Shared:  0
None:  3314
Info Table:
Name of Issuer:  United Parcel Service
Title of Class:  CL B
CUSIP:  911312-10-6
Value:  14,917,831
Shrs or Prn Amt:
Ssh Prnamt:  76900
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  76900
Shared:  0
None:  0
Info Table:
Name of Issuer:  United Parcel Service
Title of Class:  CL B
CUSIP:  911312-10-6
Value:  69,067,812
Shrs or Prn Amt:
Ssh Prnamt:  356038
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  356038
Shared:  0
None:  0
Info Table:
Name of Issuer:  United Parcel Service
Title of Class:  CL B
CUSIP:  911312-10-6
Value:  47,473,815
Shrs or Prn Amt:
Ssh Prnamt:  244723
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  244723
Shared:  0
None:  0
Info Table:
Name of Issuer:  UnitedHealth
Title of Class:  COM
CUSIP:  91324P-10-2
Value:  34,499
Shrs or Prn Amt:
Ssh Prnamt:  73
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  73
Shared:  0
None:  0
Info Table:
Name of Issuer:  Upwork Inc
Title of Class:  COM
CUSIP:  91688F-10-4
Value:  30,078,259
Shrs or Prn Amt:
Ssh Prnamt:  2657090
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2657090
Shared:  0
None:  0
Info Table:
Name of Issuer:  Upwork Inc
Title of Class:  COM
CUSIP:  91688F-10-4
Value:  22,606,753
Shrs or Prn Amt:
Ssh Prnamt:  1997063
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  610913
Shared:  0
None:  1386150
Info Table:
Name of Issuer:  Upwork Inc
Title of Class:  COM
CUSIP:  91688F-10-4
Value:  9,562,989
Shrs or Prn Amt:
Ssh Prnamt:  844787
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  771259
Shared:  0
None:  73528
Info Table:
Name of Issuer:  Upwork Inc
Title of Class:  COM
CUSIP:  91688F-10-4
Value:  15,190,387
Shrs or Prn Amt:
Ssh Prnamt:  1341907
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1341907
Shared:  0
None:  0
Info Table:
Name of Issuer:  Vale SA ADR
Title of Class:  ADR
CUSIP:  91912E-10-5
Value:  9,973
Shrs or Prn Amt:
Ssh Prnamt:  632
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  632
Shared:  0
None:  0
Info Table:
Name of Issuer:  Varonis Systems Inc
Title of Class:  COM
CUSIP:  922280-10-2
Value:  37,897
Shrs or Prn Amt:
Ssh Prnamt:  1457
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  1457
Shared:  0
None:  0
Info Table:
Name of Issuer:  Varonis Systems Inc
Title of Class:  COM
CUSIP:  922280-10-2
Value:  532,555
Shrs or Prn Amt:
Ssh Prnamt:  20475
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  20475
Shared:  0
None:  0
Info Table:
Name of Issuer:  Veeco Instruments
Title of Class:  COM
CUSIP:  922417-10-0
Value:  4,161,638
Shrs or Prn Amt:
Ssh Prnamt:  196954
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  196954
Shared:  0
None:  0
Info Table:
Name of Issuer:  Veeco Instruments
Title of Class:  COM
CUSIP:  922417-10-0
Value:  10,790,901
Shrs or Prn Amt:
Ssh Prnamt:  510691
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  147808
Shared:  0
None:  362883
Info Table:
Name of Issuer:  Veeco Instruments
Title of Class:  COM
CUSIP:  922417-10-0
Value:  4,390,708
Shrs or Prn Amt:
Ssh Prnamt:  207795
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  207795
Shared:  0
None:  0
Info Table:
Name of Issuer:  Veeva Systems Inc Class A
Title of Class:  COM
CUSIP:  922475-10-8
Value:  3,025,367
Shrs or Prn Amt:
Ssh Prnamt:  16461
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  16461
Shared:  0
None:  0
Info Table:
Name of Issuer:  Veeva Systems Inc Class A
Title of Class:  COM
CUSIP:  922475-10-8
Value:  1,404,339
Shrs or Prn Amt:
Ssh Prnamt:  7641
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  7641
Shared:  0
None:  0
Info Table:
Name of Issuer:  Veeva Systems Inc Class A
Title of Class:  COM
CUSIP:  922475-10-8
Value:  3,514,065
Shrs or Prn Amt:
Ssh Prnamt:  19120
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  19120
Shared:  0
None:  0
Info Table:
Name of Issuer:  Veritone
Title of Class:  COM
CUSIP:  92347M-10-0
Value:  3,784
Shrs or Prn Amt:
Ssh Prnamt:  649
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  649
Shared:  0
None:  0
Info Table:
Name of Issuer:  Vir Biotechnology Inc
Title of Class:  COM
CUSIP:  92764N-10-2
Value:  1,591,691
Shrs or Prn Amt:
Ssh Prnamt:  68401
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  68401
Shared:  0
None:  0
Info Table:
Name of Issuer:  Vir Biotechnology Inc
Title of Class:  COM
CUSIP:  92764N-10-2
Value:  1,926,198
Shrs or Prn Amt:
Ssh Prnamt:  82776
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  82776
Shared:  0
None:  0
Info Table:
Name of Issuer:  Vir Biotechnology Inc
Title of Class:  COM
CUSIP:  92764N-10-2
Value:  766,537
Shrs or Prn Amt:
Ssh Prnamt:  32941
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  32941
Shared:  0
None:  0
Info Table:
Name of Issuer:  Vir Biotechnology Inc
Title of Class:  COM
CUSIP:  92764N-10-2
Value:  88,470,399
Shrs or Prn Amt:
Ssh Prnamt:  3801908
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  3801908
Shared:  0
None:  0
Info Table:
Name of Issuer:  Visa Inc-Class A Shares
Title of Class:  COM CL A
CUSIP:  92826C-83-9
Value:  11,668,682
Shrs or Prn Amt:
Ssh Prnamt:  51755
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  51755
Shared:  0
None:  0
Info Table:
Name of Issuer:  Visa Inc-Class A Shares
Title of Class:  COM CL A
CUSIP:  92826C-83-9
Value:  26,604
Shrs or Prn Amt:
Ssh Prnamt:  118
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  118
Shared:  0
None:  0
Info Table:
Name of Issuer:  Visteon Corp
Title of Class:  COM
CUSIP:  92839U-20-6
Value:  39,678
Shrs or Prn Amt:
Ssh Prnamt:  253
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  253
Shared:  0
None:  0
Info Table:
Name of Issuer:  Vuzix
Title of Class:  COM
CUSIP:  92921W-30-0
Value:  3,825
Shrs or Prn Amt:
Ssh Prnamt:  924
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  924
Shared:  0
None:  0
Info Table:
Name of Issuer:  WD-40 Co
Title of Class:  COM
CUSIP:  929236-10-7
Value:  14,244
Shrs or Prn Amt:
Ssh Prnamt:  80
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  80
Shared:  0
None:  0
Info Table:
Name of Issuer:  WEC Energy Group
Title of Class:  COM
CUSIP:  92939U-10-6
Value:  1,076,151
Shrs or Prn Amt:
Ssh Prnamt:  11353
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  11353
Shared:  0
None:  0
Info Table:
Name of Issuer:  Wabtec
Title of Class:  COM
CUSIP:  929740-10-8
Value:  9,404,947
Shrs or Prn Amt:
Ssh Prnamt:  93063
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  93063
Shared:  0
None:  0
Info Table:
Name of Issuer:  Wabtec
Title of Class:  COM
CUSIP:  929740-10-8
Value:  4,687,062
Shrs or Prn Amt:
Ssh Prnamt:  46379
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  17999
Shared:  0
None:  28380
Info Table:
Name of Issuer:  Wabtec
Title of Class:  COM
CUSIP:  929740-10-8
Value:  2,874,854
Shrs or Prn Amt:
Ssh Prnamt:  28447
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  18617
Shared:  0
None:  9830
Info Table:
Name of Issuer:  Wabtec
Title of Class:  COM
CUSIP:  929740-10-8
Value:  501,157
Shrs or Prn Amt:
Ssh Prnamt:  4959
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  4959
Shared:  0
None:  0
Info Table:
Name of Issuer:  Wal-Mart Stores
Title of Class:  COM
CUSIP:  931142-10-3
Value:  20,201
Shrs or Prn Amt:
Ssh Prnamt:  137
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  137
Shared:  0
None:  0
Info Table:
Name of Issuer:  Warby Parker Inc
Title of Class:  CL A COM
CUSIP:  93403J-10-6
Value:  2,056,620
Shrs or Prn Amt:
Ssh Prnamt:  194204
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  194204
Shared:  0
None:  0
Info Table:
Name of Issuer:  Warby Parker Inc
Title of Class:  CL A COM
CUSIP:  93403J-10-6
Value:  56,634,282
Shrs or Prn Amt:
Ssh Prnamt:  5347902
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  5347902
Shared:  0
None:  0
Info Table:
Name of Issuer:  Warby Parker Inc
Title of Class:  CL A COM
CUSIP:  93403J-10-6
Value:  647,028
Shrs or Prn Amt:
Ssh Prnamt:  61098
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  39968
Shared:  0
None:  21130
Info Table:
Name of Issuer:  Warby Parker Inc
Title of Class:  CL A COM
CUSIP:  93403J-10-6
Value:  1,076,463
Shrs or Prn Amt:
Ssh Prnamt:  101649
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  37222
Shared:  0
None:  64427
Info Table:
Name of Issuer:  Waters
Title of Class:  COM
CUSIP:  941848-10-3
Value:  2,792,243
Shrs or Prn Amt:
Ssh Prnamt:  9018
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  5819
Shared:  0
None:  3199
Info Table:
Name of Issuer:  Waters
Title of Class:  COM
CUSIP:  941848-10-3
Value:  4,647,546
Shrs or Prn Amt:
Ssh Prnamt:  15010
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  5799
Shared:  0
None:  9211
Info Table:
Name of Issuer:  Waters
Title of Class:  COM
CUSIP:  941848-10-3
Value:  9,272,799
Shrs or Prn Amt:
Ssh Prnamt:  29948
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  29948
Shared:  0
None:  0
Info Table:
Name of Issuer:  Waters
Title of Class:  COM
CUSIP:  941848-10-3
Value:  485,190
Shrs or Prn Amt:
Ssh Prnamt:  1567
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1567
Shared:  0
None:  0
Info Table:
Name of Issuer:  Watsco Inc
Title of Class:  COM
CUSIP:  942622-20-0
Value:  247,445,122
Shrs or Prn Amt:
Ssh Prnamt:  777738
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  777738
Shared:  0
None:  0
Info Table:
Name of Issuer:  Watsco Inc
Title of Class:  COM
CUSIP:  942622-20-0
Value:  84,520,158
Shrs or Prn Amt:
Ssh Prnamt:  265653
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  265653
Shared:  0
None:  0
Info Table:
Name of Issuer:  Watsco Inc
Title of Class:  COM
CUSIP:  942622-20-0
Value:  30,664,261
Shrs or Prn Amt:
Ssh Prnamt:  96380
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  91051
Shared:  0
None:  5329
Info Table:
Name of Issuer:  Watsco Inc
Title of Class:  COM
CUSIP:  942622-20-0
Value:  267,848,087
Shrs or Prn Amt:
Ssh Prnamt:  841866
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  817075
Shared:  0
None:  24791
Info Table:
Name of Issuer:  Wayfair Inc Class A
Title of Class:  CL A
CUSIP:  94419L-10-1
Value:  71,940,892
Shrs or Prn Amt:
Ssh Prnamt:  2094959
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2094959
Shared:  0
None:  0
Info Table:
Name of Issuer:  Wayfair Inc Class A
Title of Class:  CL A
CUSIP:  94419L-10-1
Value:  121,716,207
Shrs or Prn Amt:
Ssh Prnamt:  3544444
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  3349490
Shared:  0
None:  194954
Info Table:
Name of Issuer:  Wayfair Inc Class A
Title of Class:  CL A
CUSIP:  94419L-10-1
Value:  11,727,213
Shrs or Prn Amt:
Ssh Prnamt:  341503
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  260923
Shared:  0
None:  80580
Info Table:
Name of Issuer:  Wayfair Inc Class A
Title of Class:  CL A
CUSIP:  94419L-10-1
Value:  89,453,365
Shrs or Prn Amt:
Ssh Prnamt:  2604932
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  2323370
Shared:  0
None:  281562
Info Table:
Name of Issuer:  West Pharmaceutical Services
Title of Class:  COM
CUSIP:  955306-10-5
Value:  15,938
Shrs or Prn Amt:
Ssh Prnamt:  46
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  46
Shared:  0
None:  0
Info Table:
Name of Issuer:  Wheaton Precious Metals
Title of Class:  COM
CUSIP:  962879-10-2
Value:  1,570,787
Shrs or Prn Amt:
Ssh Prnamt:  32616
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  32616
Shared:  0
None:  0
Info Table:
Name of Issuer:  Williams-Sonoma Inc
Title of Class:  COM
CUSIP:  969904-10-1
Value:  7,665
Shrs or Prn Amt:
Ssh Prnamt:  63
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  63
Shared:  0
None:  0
Info Table:
Name of Issuer:  Wix Com
Title of Class:  SHS
CUSIP:  M98068-10-5
Value:  800,747,396
Shrs or Prn Amt:
Ssh Prnamt:  8023521
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  5968062
Shared:  0
None:  2055459
Info Table:
Name of Issuer:  Wix Com
Title of Class:  SHS
CUSIP:  M98068-10-5
Value:  43,014
Shrs or Prn Amt:
Ssh Prnamt:  431
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  431
Shared:  0
None:  0
Info Table:
Name of Issuer:  Workday Inc
Title of Class:  CL A
CUSIP:  98138H-10-1
Value:  133,115,237
Shrs or Prn Amt:
Ssh Prnamt:  644501
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  551163
Shared:  0
None:  93338
Info Table:
Name of Issuer:  Workday Inc
Title of Class:  CL A
CUSIP:  98138H-10-1
Value:  887,387,337
Shrs or Prn Amt:
Ssh Prnamt:  4296443
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2460884
Shared:  0
None:  1835559
Info Table:
Name of Issuer:  Workday Inc
Title of Class:  CL A
CUSIP:  98138H-10-1
Value:  257,971,145
Shrs or Prn Amt:
Ssh Prnamt:  1249013
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1249013
Shared:  0
None:  0
Info Table:
Name of Issuer:  Workday Inc
Title of Class:  CL A
CUSIP:  98138H-10-1
Value:  235,152,193
Shrs or Prn Amt:
Ssh Prnamt:  1138531
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  593388
Shared:  0
None:  545143
Info Table:
Name of Issuer:  XP
Title of Class:  CL A
CUSIP:  G98239-10-9
Value:  637,763
Shrs or Prn Amt:
Ssh Prnamt:  53729
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  53729
Shared:  0
None:  0
Info Table:
Name of Issuer:  XP
Title of Class:  CL A
CUSIP:  G98239-10-9
Value:  2,040,500
Shrs or Prn Amt:
Ssh Prnamt:  171904
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  12129
Shared:  0
None:  159775
Info Table:
Name of Issuer:  XP
Title of Class:  CL A
CUSIP:  G98239-10-9
Value:  2,057,653
Shrs or Prn Amt:
Ssh Prnamt:  173349
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  22057
Shared:  0
None:  151292
Info Table:
Name of Issuer:  XP
Title of Class:  CL A
CUSIP:  G98239-10-9
Value:  105,560
Shrs or Prn Amt:
Ssh Prnamt:  8893
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  04
Voting Authority:
Sole:  8893
Shared:  0
None:  0
Info Table:
Name of Issuer:  XPEL
Title of Class:  COM
CUSIP:  98379L-10-0
Value:  25,074
Shrs or Prn Amt:
Ssh Prnamt:  369
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  369
Shared:  0
None:  0
Info Table:
Name of Issuer:  Xencor Inc
Title of Class:  COM
CUSIP:  98401F-10-5
Value:  58,011
Shrs or Prn Amt:
Ssh Prnamt:  2080
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2080
Shared:  0
None:  0
Info Table:
Name of Issuer:  Xencor Inc
Title of Class:  COM
CUSIP:  98401F-10-5
Value:  827,608
Shrs or Prn Amt:
Ssh Prnamt:  29674
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  29674
Shared:  0
None:  0
Info Table:
Name of Issuer:  Xperi
Title of Class:  COM
CUSIP:  98423J-10-1
Value:  6,328
Shrs or Prn Amt:
Ssh Prnamt:  579
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  579
Shared:  0
None:  0
Info Table:
Name of Issuer:  Xylem
Title of Class:  COM
CUSIP:  98419M-10-0
Value:  115,706,169
Shrs or Prn Amt:
Ssh Prnamt:  1105121
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1105121
Shared:  0
None:  0
Info Table:
Name of Issuer:  Xylem
Title of Class:  COM
CUSIP:  98419M-10-0
Value:  71,726,829
Shrs or Prn Amt:
Ssh Prnamt:  685070
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  419690
Shared:  0
None:  265380
Info Table:
Name of Issuer:  Xylem
Title of Class:  COM
CUSIP:  98419M-10-0
Value:  116,019,955
Shrs or Prn Amt:
Ssh Prnamt:  1108118
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  875142
Shared:  0
None:  232976
Info Table:
Name of Issuer:  Xylem
Title of Class:  COM
CUSIP:  98419M-10-0
Value:  33,975,883
Shrs or Prn Amt:
Ssh Prnamt:  324507
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  97898
Shared:  0
None:  226609
Info Table:
Name of Issuer:  Zillow Group Inc Class A
Title of Class:  CL A
CUSIP:  98954M-10-1
Value:  1,354,263
Shrs or Prn Amt:
Ssh Prnamt:  30990
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  30990
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zillow Group Inc Class A
Title of Class:  CL A
CUSIP:  98954M-10-1
Value:  6,699,734
Shrs or Prn Amt:
Ssh Prnamt:  153312
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  45088
Shared:  0
None:  108224
Info Table:
Name of Issuer:  Zillow Group Inc Class A
Title of Class:  CL A
CUSIP:  98954M-10-1
Value:  2,363,646
Shrs or Prn Amt:
Ssh Prnamt:  54088
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  54088
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zillow Group Inc Class A
Title of Class:  CL A
CUSIP:  98954M-10-1
Value:  3,969,708
Shrs or Prn Amt:
Ssh Prnamt:  90840
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  90840
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zillow Group Inc Class C
Title of Class:  CL C CAP STK
CUSIP:  98954M-20-0
Value:  10,596,890
Shrs or Prn Amt:
Ssh Prnamt:  238293
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  238293
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zillow Group Inc Class C
Title of Class:  CL C CAP STK
CUSIP:  98954M-20-0
Value:  25,951,491
Shrs or Prn Amt:
Ssh Prnamt:  583573
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  583573
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zillow Group Inc Class C
Title of Class:  CL C CAP STK
CUSIP:  98954M-20-0
Value:  30,056,250
Shrs or Prn Amt:
Ssh Prnamt:  675877
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  195505
Shared:  0
None:  480372
Info Table:
Name of Issuer:  Zillow Group Inc Class C
Title of Class:  CL C CAP STK
CUSIP:  98954M-20-0
Value:  43,387,111
Shrs or Prn Amt:
Ssh Prnamt:  975649
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  975649
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zoom Video Communications Inc
Title of Class:  CL A
CUSIP:  98980L-10-1
Value:  154,432,003
Shrs or Prn Amt:
Ssh Prnamt:  2091441
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  1612406
Shared:  0
None:  479035
Info Table:
Name of Issuer:  Zoom Video Communications Inc
Title of Class:  CL A
CUSIP:  98980L-10-1
Value:  41,492,837
Shrs or Prn Amt:
Ssh Prnamt:  561929
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  483971
Shared:  0
None:  77958
Info Table:
Name of Issuer:  Zoom Video Communications Inc
Title of Class:  CL A
CUSIP:  98980L-10-1
Value:  316,095,896
Shrs or Prn Amt:
Ssh Prnamt:  4280822
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  2673954
Shared:  0
None:  1606868
Info Table:
Name of Issuer:  Zoom Video Communications Inc
Title of Class:  CL A
CUSIP:  98980L-10-1
Value:  102,995,724
Shrs or Prn Amt:
Ssh Prnamt:  1394850
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  1394850
Shared:  0
None:  0
Info Table:
Name of Issuer:  ZoomInfo Technologies
Title of Class:  COM
CUSIP:  98980F-10-4
Value:  11,021
Shrs or Prn Amt:
Ssh Prnamt:  446
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  446
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zuora Inc Class A
Title of Class:  COM CL A
CUSIP:  98983V-10-6
Value:  7,720,588
Shrs or Prn Amt:
Ssh Prnamt:  781436
Ssh Prnamt Type:  SH
Investment Discretion:  SOLE
Other Manager:  0
Voting Authority:
Sole:  781436
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zuora Inc Class A
Title of Class:  COM CL A
CUSIP:  98983V-10-6
Value:  6,773,372
Shrs or Prn Amt:
Ssh Prnamt:  685564
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  685564
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zuora Inc Class A
Title of Class:  COM CL A
CUSIP:  98983V-10-6
Value:  16,133,487
Shrs or Prn Amt:
Ssh Prnamt:  1632944
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  472046
Shared:  0
None:  1160898
Info Table:
Name of Issuer:  Zuora Inc Class A
Title of Class:  COM CL A
CUSIP:  98983V-10-6
Value:  19,861,013
Shrs or Prn Amt:
Ssh Prnamt:  2010224
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  2010224
Shared:  0
None:  0
Info Table:
Name of Issuer:  Zynex
Title of Class:  COM
CUSIP:  98986M-10-3
Value:  5,772
Shrs or Prn Amt:
Ssh Prnamt:  481
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  481
Shared:  0
None:  0
Info Table:
Name of Issuer:  dLocal
Title of Class:  CL A
CUSIP:  G29018-10-1
Value:  8,981,468
Shrs or Prn Amt:
Ssh Prnamt:  553728
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  553728
Shared:  0
None:  0
Info Table:
Name of Issuer:  dLocal
Title of Class:  CL A
CUSIP:  G29018-10-1
Value:  3,309,659
Shrs or Prn Amt:
Ssh Prnamt:  204048
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  0
Shared:  0
None:  204048
Info Table:
Name of Issuer:  dLocal
Title of Class:  CL A
CUSIP:  G29018-10-1
Value:  1914
Shrs or Prn Amt:
Ssh Prnamt:  118
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  118
Shared:  0
None:  0
Info Table:
Name of Issuer:  iRobot
Title of Class:  COM
CUSIP:  462726-10-0
Value:  1,206,035
Shrs or Prn Amt:
Ssh Prnamt:  27636
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  01
Voting Authority:
Sole:  27636
Shared:  0
None:  0
Info Table:
Name of Issuer:  iRobot
Title of Class:  COM
CUSIP:  462726-10-0
Value:  2,892,983
Shrs or Prn Amt:
Ssh Prnamt:  66292
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  66292
Shared:  0
None:  0
Info Table:
Name of Issuer:  iRobot
Title of Class:  COM
CUSIP:  462726-10-0
Value:  7,667,897
Shrs or Prn Amt:
Ssh Prnamt:  175708
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  02
Voting Authority:
Sole:  53631
Shared:  0
None:  122077
Info Table:
Name of Issuer:  nLIGHT
Title of Class:  COM
CUSIP:  65487K-10-0
Value:  4,764
Shrs or Prn Amt:
Ssh Prnamt:  468
Ssh Prnamt Type:  SH
Investment Discretion:  DFND
Other Manager:  03
Voting Authority:
Sole:  468
Shared:  0
None:  0


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