As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

 6/10/21‡ Frost Phillip MD et al            SC 13D/A     6/9/21    1:64K  Cocrystal Pharma, Inc.            Toppan Merrill/FA        
          Frost Gamma Investments Trust³
          Steven D. Rubin³
11/19/20  Opko Health, Inc.                 SC 13D/A               1:146K Cocrystal Pharma, Inc.                                     
          Frost Gamma Investments Trust³
          Phillip Frost, M.D.³
          Steven D. Rubin³

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‡	A non-Insider-Ownership Filing that was accepted after the SEC “closed” at 5:30:00pm ET.  The legal “Filed As Of” date may be the next, or another, day.
¹	Filing/Form Type:  -K
	SC 13D	Statement of Acquisition of Beneficial Ownership by an “Active” Investor — Schedule 13D.
	/A	Amendment to, or Amended version of, a previous Filing of this Type.
³	Group Member:  A Registrant or non-Registrant party to this Filing made by a Group.