As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

  3/9/09  Frost Gamma Investments Trust     4          D,O,%Owner² 2:22K  Opko Health, Inc.                 Toppan Merrill/FA        
          Frost Phillip MD et al
  3/9/09  Frost Gamma Investments Trust     4          D,O,%Owner² 2:42K  Opko Health, Inc.                 Toppan Merrill/FA        
          Frost Phillip MD et al
  3/6/09  Opko Health, Inc.                 8-K:1,2,8,9  3/4/09    2:23K                                    Bowne of Atlanta Inc./FA 
  3/6/09  Frost Phillip MD et al            4          D,O,%Owner² 2:28K  Opko Health, Inc.                 Toppan Merrill/FA        
          Frost Gamma Investments Trust
  3/6/09‡ Opko Health, Inc.                 DEF 14C     2/13/09    1:182K                                   Bowne of Atlanta Inc./FA 

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‡	A non-Insider-Ownership Filing that was accepted after the SEC “closed” at 5:30:00pm ET.  The legal “Filed As Of” date may be the next, or another, day.
¹	Filing/Form Types:  -A
	4	Statement of Changes in Beneficial Ownership of Securities by an Insider — Form 4 { The Filer is an Insider² of the Issuer }.
	8-K	Current Report — Form 8-K { Item 1: Business & Operations;  2: Financial Info;  3: Securities & Trading;  4: Accountants & Accounting;  5: Governance & Management;  6: Asset-Backed Securities;  7: Disclosures;  8: Events;  9: Financials }.
	DEF 14C	Definitive Proxy Info Statement — Schedule 14C.
²	Insider:  The Filer is a Director, Officer, 10% Owner and/or Other “insider” of the Issuer.