As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

 3/30/07  Rubin Steven D                    4          Director²   1:18K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
 3/30/07  Hsiao Jane PhD                    4          Director²   1:18K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
 3/30/07  Frost Phillip MD et al            4          D,O,%Owner² 1:19K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
 3/30/07  Frost Group, LLC                  4          10% Owner²  1:12K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
 3/30/07  Frost Gamma Investments Trust     4/A        10% Owner²  1:18K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 

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¹	Filing/Form Type:  -K
	4	Statement of Changes in Beneficial Ownership of Securities by an Insider — Form 4 { The Filer is an Insider² of the Issuer }.
	/A	Amendment to, or Amended version of, a previous Filing of this Type.
²	Insider:  The Filer is a Director, Officer, 10% Owner and/or Other “insider” of the Issuer.