As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

11/10/11  Frost Phillip MD et al            4          D,O,%Owner² 2:18K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
          Frost Gamma Investments Trust
 11/9/11  Opko Health, Inc.                 10-Q        9/30/11   34:2.7M                                   Donnelley … Solutions/FA 
 11/9/11  Frost Phillip MD et al            4          D,O,%Owner² 2:20K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
          Frost Gamma Investments Trust

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¹	Filing/Form Types:  /A
	4	Statement of Changes in Beneficial Ownership of Securities by an Insider — Form 4 { The Filer is an Insider² of the Issuer }.
	10-Q	Quarterly Report — Form 10-Q.
²	Insider:  The Filer is a Director, Officer, 10% Owner and/or Other “insider” of the Issuer.