As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

 1/25/12  Opko Health, Inc.                 8-K/A:9    12/29/11    4:617K                                   Donnelley … Solutions/FA 
12/30/11  Frost Phillip MD et al            4          D,O,%Owner² 2:12K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
          Frost Gamma Investments Trust
12/29/11  Opko Health, Inc.                 424B3                  1:44K                                    Donnelley … Solutions/FA 
12/29/11  Opko Health, Inc.                 8-K:2,3,7,912/29/11    2:41K                                    Donnelley … Solutions/FA 
12/29/11  Frost Phillip MD et al            4          D,O,%Owner² 2:11K  Opko Health, Inc.                 DONNELLEY FIN… File16/FA 
          Frost Gamma Investments Trust

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¹	Filing/Form Types:
	4	Statement of Changes in Beneficial Ownership of Securities by an Insider — Form 4 { The Filer is an Insider² of the Issuer }.
	8-K	Current Report — Form 8-K { Item 1: Business & Operations;  2: Financial Info;  3: Securities & Trading;  4: Accountants & Accounting;  5: Governance & Management;  6: Asset-Backed Securities;  7: Disclosures;  8: Events;  9: Financials }.
	424B3	Prospectus – New Facts or Events.
	/A	Amendment to, or Amended version of, a previous Filing of this Type.
²	Insider:  The Filer is a Director, Officer, 10% Owner and/or Other “insider” of the Issuer.