As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

 5/27/08  Opko Health, Inc.                 ARS        12/31/07    1:2K                                     SEC #7                   
 3/31/08  Opko Health, Inc.                 10-K       12/31/07   13:2.7M                                   Toppan Merrill/FA        
  1/3/08  Frost Phillip MD et al            4          D,O,%Owner² 2:20K  Opko Health, Inc.                 R R Donnelley … Filer/FA 
          Frost Gamma Investment Trust

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¹	Filing/Form Types:
	4	Statement of Changes in Beneficial Ownership of Securities by an Insider — Form 4 { The Filer is an Insider² of the Issuer }.
	10-K	Annual Report — Form 10-K.
	ARS	Annual Report to Security Holders.
²	Insider:  The Filer is a Director, Officer, 10% Owner and/or Other “insider” of the Issuer.