As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

 6/30/08  Paganelli John A                  4/A        Dir.,Other² 1:4K   Opko Health, Inc.                 Toppan Merrill/FA        
 2/16/07  Paganelli John A                  4          Dir.,Other² 1:4K   Opko Health, Inc.                 Toppan Merrill/FA        
 2/15/07  Frost Phillip MD et al            3          10% Owner²  2:6K   Opko Health, Inc.                 Toppan Merrill/FA        
          Frost Gamma Investment Trust
 2/13/07  Frost Group, LLC                  3          10% Owner²  1:4K   Opko Health, Inc.                 Toppan Merrill/FA        
 2/13/07  Hsiao Jane PhD                    3          Director²   1:4K   Opko Health, Inc.                 Toppan Merrill/FA        
 2/13/07  Rubin Steven D                    3          Director²   1:4K   Opko Health, Inc.                 Toppan Merrill/FA        
 2/13/07  Uppaluri Subbarao V               3          Director²   1:4K   Opko Health, Inc.                 Toppan Merrill/FA        
  2/9/07  Opko Health, Inc.                 8-K:3,5,8,9  2/9/07    2:73K                                    Toppan Merrill/FA        

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¹	Filing/Form Types:
	3	Initial Statement of Beneficial Ownership of Securities by an Insider — Form 3 { The Filer is an Insider² of the Issuer }.
	4	Statement of Changes in Beneficial Ownership of Securities by an Insider — Form 4 { The Filer is an Insider² of the Issuer }.
	8-K	Current Report — Form 8-K { Item 1: Business & Operations;  2: Financial Info;  3: Securities & Trading;  4: Accountants & Accounting;  5: Governance & Management;  6: Asset-Backed Securities;  7: Disclosures;  8: Events;  9: Financials }.
	/A	Amendment to, or Amended version of, a previous Filing of this Type.
²	Insider:  The Filer is a Director, Officer, 10% Owner and/or Other “insider” of the Issuer.