As Of	Filer	Filing¹	For·On·As	Docs:Size	Issuer		Filing Agent

  1/3/14  Smith James Francis               4          Director²   1:6K   Echo Therapeutics, Inc.           SEC Connect              
 10/2/13  Smith James Francis               4          Director²   1:7K   Echo Therapeutics, Inc.           SEC Connect              
  7/9/13  Smith James Francis               4/A        Director²   1:7K   Echo Therapeutics, Inc.           SEC Connect              
  7/2/13  Smith James Francis               4          Director²   1:7K   Echo Therapeutics, Inc.           SEC Connect              
 4/11/13  Smith James Francis               4          Director²   1:5K   Echo Therapeutics, Inc.           SEC Connect              
 4/10/13  Smith James Francis               4          Director²   1:5K   Echo Therapeutics, Inc.           SEC Connect              
 1/11/13  Smith James Francis               4          Director²   1:5K   Echo Therapeutics, Inc.           SEC Connect              
 10/2/12  Smith James Francis               4          Director²   1:5K   Echo Therapeutics, Inc.           SEC Connect              
 8/23/12  Smith James Francis               4          Director²   1:5K   Echo Therapeutics, Inc.           SEC Connect              
  7/3/12  Smith James Francis               4          Director²   1:5K   Echo Therapeutics, Inc.           SEC Connect              
12/19/11  Smith James Francis               4          Officer²    1:9K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 
12/13/11  Smith James Francis               4          Officer²    1:4K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 
 2/18/11  Smith James Francis               4          Director²   1:4K   Echo Therapeutics, Inc.           SEC Connect              
 2/17/11  Smith James Francis               3          Director²   2:7K   Echo Therapeutics, Inc.           SEC Connect              
 5/27/10  Smith James Francis               4          Officer²    1:4K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 
 6/29/09  Smith James Francis               4          Officer²    1:6K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 
  8/6/08  Smith James Francis               4          Officer²    1:4K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 
  6/9/08  Smith James Francis               4          Officer²    1:4K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 
 11/1/07  Smith James Francis               4          Officer²    1:4K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 
10/19/07  Smith James Francis               3          Officer²    1:3K   Orchid Cellmark Inc.              R R Donnelley … Filer/FA 

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¹	Filing/Form Types:
	3	Initial Statement of Beneficial Ownership of Securities by an Insider — Form 3 { The Filer is an Insider² of the Issuer }.
	4	Statement of Changes in Beneficial Ownership of Securities by an Insider — Form 4 { The Filer is an Insider² of the Issuer }.
	/A	Amendment to, or Amended version of, a previous Filing of this Type.
²	Insider:  The Filer is a Director, Officer, 10% Owner and/or Other “insider” of the Issuer.