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Thermo Fisher Scientific Inc., et al. – ‘4’ for 3/12/24 re: Science 37 Holdings, Inc.

On:  Thursday, 3/14/24, at 4:26pm ET   ·   For:  3/12/24   ·   As:  10% Owner   ·   Accession #:  950157-24-417   ·   File #:  1-39727

Previous ‘4’:  ‘4’ on 3/14/24 for 3/12/24   ·   Latest ‘4’:  This Filing

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  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/14/24  Thermo Fisher Scientific Inc.     4          10% Owner   1:16K  Science 37 Holdings, Inc.         Cravath Swaine & … 01/FA
          Spectra-Physics Holdings USA, LLC
          Thermo Fisher Scientific Powder Holdings III
          Fisher Scientific International LLC
          Thermo Fisher Scientific Powder Holdings I
          Thermo Fisher Scientific Powder Holdings II
          Fisher Scientific Worldwide Inc.

Statement of Changes in Beneficial Ownership of Securities by an Insider   —   Form 4   —   SEA’34

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 4           Statement of Changes in Beneficial Ownership of     HTML     14K 
                Securities by an Insider -- form4.xml/5.8


        

This ‘4’ Document is an XML Data File that may be rendered in various formats:

  Form 4    –   Plain Text   –  SEC Website  –  EDGAR System  –    XML Data    –  <?xml?> File
 
 
SEC Info℠ rendering:  Statement of Changes in Beneficial Ownership of Securities by an Insider
 

The SEC has not released XSLT Stylesheets needed to render this File’s XML Data as a Form.

This is our “Plain Text” rendering:
 
                                                                                                                                                                                
Ownership Document
 
Schema Version:  X0508
Document Type:  4
Period of Report:  3/12/24
Not Subject to Section 16?  Yes
Issuer:
Issuer CIK:  1819113
Issuer Name:  Science 37 Holdings, Inc.
Issuer Trading Symbol:  SNCE
Reporting Owner:
Reporting Owner ID:
Owner CIK:  97745
Owner Name:  THERMO FISHER SCIENTIFIC INC.
Reporting Owner Address:
Owner Street 1:  168 THIRD AVENUE
Owner Street 2:
Owner City:  WALTHAM
Owner State:  MA
Owner ZIP Code:  02451
Owner State Description:
Reporting Owner Relationship:
Is Ten Percent Owner?  Yes
Reporting Owner:
Reporting Owner ID:
Owner CIK:  1920540
Owner Name:  Thermo Fisher Scientific Powder Holdings III
Reporting Owner Address:
Owner Street 1:  168 THIRD AVENUE
Owner Street 2:
Owner City:  WALTHAM
Owner State:  MA
Owner ZIP Code:  02451
Owner State Description:
Reporting Owner Relationship:
Is Ten Percent Owner?  Yes
Reporting Owner:
Reporting Owner ID:
Owner CIK:  1920609
Owner Name:  Thermo Fisher Scientific Powder Holdings II
Reporting Owner Address:
Owner Street 1:  168 THIRD AVENUE
Owner Street 2:
Owner City:  WALTHAM
Owner State:  MA
Owner ZIP Code:  02451
Owner State Description:
Reporting Owner Relationship:
Is Ten Percent Owner?  Yes
Reporting Owner:
Reporting Owner ID:
Owner CIK:  1920599
Owner Name:  Thermo Fisher Scientific Powder Holdings I
Reporting Owner Address:
Owner Street 1:  168 THIRD AVENUE
Owner Street 2:
Owner City:  WALTHAM
Owner State:  MA
Owner ZIP Code:  02451
Owner State Description:
Reporting Owner Relationship:
Is Ten Percent Owner?  Yes
Reporting Owner:
Reporting Owner ID:
Owner CIK:  1920570
Owner Name:  Spectra-Physics Holdings USA, LLC
Reporting Owner Address:
Owner Street 1:  168 THIRD AVENUE
Owner Street 2:
Owner City:  WALTHAM
Owner State:  MA
Owner ZIP Code:  02451
Owner State Description:
Reporting Owner Relationship:
Is Ten Percent Owner?  Yes
Reporting Owner:
Reporting Owner ID:
Owner CIK:  1920616
Owner Name:  Fisher Scientific Worldwide Inc.
Reporting Owner Address:
Owner Street 1:  168 THIRD AVENUE
Owner Street 2:
Owner City:  WALTHAM
Owner State:  MA
Owner ZIP Code:  02451
Owner State Description:
Reporting Owner Relationship:
Is Ten Percent Owner?  Yes
Reporting Owner:
Reporting Owner ID:
Owner CIK:  1921286
Owner Name:  Fisher Scientific International LLC
Reporting Owner Address:
Owner Street 1:  168 THIRD AVENUE
Owner Street 2:
Owner City:  WALTHAM
Owner State:  MA
Owner ZIP Code:  02451
Owner State Description:
Reporting Owner Relationship:
Is Ten Percent Owner?  Yes
Aff 10b5 One?  No
Non-Derivative Table:
Non-Derivative Transaction:
Security Title:
Value:  Common Stock
Transaction Date:
Value:  3/12/24
Transaction Coding:
Transaction Form Type:  4
Transaction Code:  U
Equity Swap Involved?  No
Transaction Amounts:
Transaction Shares:
Value:  868,990
Transaction Price Per Share:
Value:  5.75
Transaction Acquired-Disposed Code:
Value:  D
Post-Transaction Amounts:
Shares Owned Following Transaction:
Value:  0
Ownership Nature:
Direct or Indirect Ownership:
Value:  I
Footnote ID:  F1
Footnote ID:  F2
Footnote ID:  F3
Footnote ID:  F4
Footnote ID:  F5
Nature of Ownership:
Value:  See footnote
Footnote ID:  F1
Footnote ID:  F2
Footnote ID:  F3
Footnote ID:  F4
Footnotes:
Footnote - F1:  For the reasons discussed in the Remarks below, this and a separate Form 4 filed today are being jointly filed by and on behalf of each of the persons listed in footnote 2 (the "Reporting Persons"). The Reporting Persons are making these joint filings because they may be deemed to constitute a "group" within the meaning of Section 13(d)(3) of the Securities Exchange Act of 1934, as amended (the "Exchange Act").
Footnote - F2:  Reporting Persons: (i) Pharmaceutical Product Development, LLC ("Pharma LLC"); (ii) Wildcat Acquisition Holdings (UK) Limited ("Wildcat"); (iii) Jaguar Holding Company II ("Jaguar II"); (iv) Jaguar Holding Company I, LLC ("Jaguar I"); (v) Eagle Holding Company II, LLC ("Eagle II"); (vi) PPD, Inc. ("PPD"); (vii) Thermo Fisher Scientific Powder US Holdings Corp. ("Powder Holdings"); (viii) Thermo Fisher Scientific US Holdings Ltd ("US Holdings"); (ix) Thermo Fisher Scientific Powder Holdings II Ltd ("Powder Holdings II"); (x) Thermo Fisher Scientific Powder Holdings IV Ltd ("Powder Holdings IV"); (xi) Thermo Fisher Scientific Powder Holdings I Ltd ("Powder Holdings I"); (xii) Thermo Fisher Scientific Powder Holdings III Ltd ("Powder Holdings III"); (xiii) Spectra-Physics Holdings USA, LLC; (xiv); Fisher Scientific Worldwide Inc. ("Worldwide"); (xv) Fisher Scientific International LLC ("Scientific International"); and (xvi) Thermo Fisher Scientific Inc. ("Thermo Fisher").
Footnote - F3:  The referenced shares of common stock, par value $0.0001 per share, of Science 37 Holdings, Inc. (the "Issuer") were held of record by Pharma LLC. The Reporting Persons' ownership of Pharma LLC is summarized as follows here and in footnote 4. Wildcat is the sole member of Pharma LLC; Jaguar II is the sole shareholder of Wildcat; Jaguar I is the sole shareholder of Jaguar II; Eagle II is the sole member of Jaguar I; PPD is the sole member of Eagle II; Powder Holdings is the sole shareholder of PPD; US Holdings is the sole shareholder of Powder Holdings; Powder Holdings II is the sole shareholder of US Holdings; Powder Holdings IV and Powder Holdings I are the 11.76% shareholder and the 88.24% shareholder, respectively, of Powder Holdings II.
Footnote - F4:  Powder Holdings III is the sole shareholder of Powder Holdings IV; Spectra-Physics is the sole shareholder of Powder Holdings I; Worldwide is the sole member of Spectra-Physics; Scientific International is the sole shareholder of Worldwide; Scientific International is the sole shareholder of Powder Holdings III; and Thermo Fisher is the sole member of Scientific International. By virtue of such relationships and the relationships discussed in footnote 3, each of the Reporting Persons may be deemed to have beneficial ownership over the shares of common stock discussed in footnote 3.
Footnote - F5:  Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Exchange Act, except to the extent of its pecuniary interest therein.
Remarks:  Because an electronically filed joint filing is limited to a maximum of ten reporting persons, this Form 4 is one of two filed today reporting on the same classes of securities of the same Issuer by the joint filers named in footnote 2 above. Each Form 4 will be filed by Thermo Fisher. On December 8, 2023, the Issuer effected a reverse stock split of its common stock at a ratio of 1-for-20 (the "Reverse Stock Split"). As a result of the Reverse Stock Split, the shares of Issuer common stock have been adjusted accordingly.
Owner Signature:
Signature Name:  Thermo Fisher Scientific Inc., /s/ Michael Boxer, Senior Vice President and General Counsel
Signature Date:  3/14/24
Owner Signature:
Signature Name:  Thermo Fisher Scientific Powder Holdings III Ltd, /s/ Anthony H. Smith, Director
Signature Date:  3/14/24
Owner Signature:
Signature Name:  Thermo Fisher Scientific Powder Holdings II Ltd, /s/ Anthony H. Smith, Director
Signature Date:  3/14/24
Owner Signature:
Signature Name:  Thermo Fisher Scientific Powder Holdings I Ltd, /s/ Anthony H. Smith, Director
Signature Date:  3/14/24
Owner Signature:
Signature Name:  Spectra-Physics Holdings USA, LLC, /s/ Anthony H. Smith, Treasurer and Assistant Secretary
Signature Date:  3/14/24
Owner Signature:
Signature Name:  Fisher Scientific Worldwide Inc., /s/ Anthony H. Smith, Treasurer and Assistant Secretary
Signature Date:  3/14/24
Owner Signature:
Signature Name:  Fisher Scientific International LLC, /s/ Anthony H. Smith, Vice President and Treasurer
Signature Date:  3/14/24


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