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| <link:definition> 00400 - Disclosure - In-process R and D charge </link:definition> |
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| <link:definition> 00700 - Disclosure - Accounts receivable, net </link:definition> |
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| <link:definition> 01000 - Disclosure - Prepaid expenses and other current assets </link:definition> |
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| <link:definition> 01100 - Disclosure - Investments </link:definition> |
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| <link:definition> 01200 - Disclosure - Other intangible assets, net </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| | | <link:roleType roleURI="http://www.shire.com/role/AccountsPayableAndAccruedExpenses" id="AccountsPayableAndAccruedExpenses"> |
| <link:definition> 01300 - Disclosure - Accounts payable and accrued expenses </link:definition> |
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| <link:definition> 01400 - Disclosure - Other current liabilities </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 01500 - Disclosure - Other non-current liabilities </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 01700 - Disclosure - Commitments and contingencies </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 01550 - Disclosure - Derivative instruments </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 01600 - Disclosure - Fair value measurement </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 01900 - Disclosure - Earnings per share </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 02000 - Disclosure - Segmental reporting </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 02080 - Disclosure - Taxation </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| | | <link:roleType roleURI="http://www.shire.com/role/GainOnSaleOfProductRights" id="GainOnSaleOfProductRights"> |
| <link:definition> 00410 - Disclosure - Gain on sale of product rights </link:definition> |
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| <link:definition> 02040 - Disclosure - Other income (expenses), net </link:definition> |
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| <link:definition> 01450 - Disclosure - Other long-term debt </link:definition> |
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| <link:definition> 00150 - Disclosure - Summary Of Significant Accounting Policies </link:definition> |
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| <link:usedOn> link:calculationLink </link:usedOn> |
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| <link:definition> 01125 - Disclosure - Property Plant and Equipment, net </link:definition> |
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| <link:definition> 01150 - Disclosure - Goodwill </link:definition> |
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| <link:definition> 01425 - Disclosure - Long-term debt </link:definition> |
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| <link:definition> 02060 - Disclosure - Retirement benefits </link:definition> |
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| <link:definition> 02100 - Disclosure - Share-based compensation plans </link:definition> |
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| <link:definition> 02400 - Disclosure - Subsequent Events </link:definition> |
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| <link:definition> 02600 - Disclosure - Valuation and Qualifying Accounts Schedule </link:definition> |
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| <link:definition> 02020 - Disclosure - Interest expense </link:definition> |
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| <link:definition> 02200 - Disclosure - Restatement of previously issued financial statements </link:definition> |
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| <link:definition> 02500 - Disclosure - Income Access Share Trust Financial Statements </link:definition> |
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| <xsd:element name="CommonShareParValueAxis" id="shpgf_CommonShareParValueAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="OtherNoncurrentLiabilitiesDisclosureTextBlock" id="shpgf_OtherNoncurrentLiabilitiesDisclosureTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="DocumentAndEntityInformationAbstract" id="shpgf_DocumentAndEntityInformationAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="PrepaidExpenseAndOtherAssetsCurrent" id="shpgf_PrepaidExpenseAndOtherAssetsCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="instant"/> |
| <xsd:element name="TerminationCostsTextBlock" id="shpgf_TerminationCostsTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="CommonShareParValueTable" id="shpgf_CommonShareParValueTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" abstract="true" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="CommonStockParValueMember" id="shpgf_CommonStockParValueMember" type="us-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="InterestExpenseNonOperating" id="shpgf_InterestExpenseNonOperating" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/> |
| <xsd:element name="EquityMethodInvestmentReturns" id="shpgf_EquityMethodInvestmentReturns" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="SharesPurchasedDuringPeriodByESOT" id="shpgf_SharesPurchasedDuringPeriodByESOT" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/> |
| <xsd:element name="MinorityInterestIncreaseFromCapitalContributionsToNoncontrollingInterestHolders" id="shpgf_MinorityInterestIncreaseFromCapitalContributionsToNoncontrollingInterestHolders" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="SharesReleasedDuringPeriodByESOT" id="shpgf_SharesReleasedDuringPeriodByESOT" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="InProcessResearchAndDevelopmentTextBlock" id="shpgf_InProcessResearchAndDevelopmentTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="ReorganizationItemsTextBlock" id="shpgf_ReorganizationItemsTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="IntegrationAndAcquisitionCostsTextBlock" id="shpgf_IntegrationAndAcquisitionCostsTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="IncreaseDecreaseInSalesDeductionAccrual" id="shpgf_IncreaseDecreaseInSalesDeductionAccrual" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/> |
| <xsd:element name="BuildingFinancingObligation" id="shpgf_BuildingFinancingObligation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="GainLossOnDispositionOfProductRights" id="shpgf_GainLossOnDispositionOfProductRights" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="GainLossOnDispositionOfProductRightsTextBlock" id="shpgf_GainLossOnDispositionOfProductRightsTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="LongTermDebtDisclosureTextBlock" id="shpgf_LongTermDebtDisclosureTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="ResearchAndDevelopmentInProcessBusinessCombination" id="shpgf_ResearchAndDevelopmentInProcessBusinessCombination" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/> |
| <xsd:element name="NoncashOrPartNoncashProductOutLicensingAmountOfConsiderationReceived" id="shpgf_NoncashOrPartNoncashProductOutLicensingAmountOfConsiderationReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/> |
| <xsd:element name="OtherAssetsNoncurrentTextBlock" id="shpgf_OtherAssetsNoncurrentTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="SubsequentEventsTextblock" id="shpgf_SubsequentEventsTextblock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="ProceedsFromExerciseOfWarrants" id="shpgf_ProceedsFromExerciseOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/> |
| <xsd:element name="ExchangeStockMember" id="shpgf_ExchangeStockMember" type="us-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="ExchangeOfStockForStockDuringPeriod" id="shpgf_ExchangeOfStockForStockDuringPeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/> |
| <xsd:element name="AdjustmentsToAdditionalPaidInCapitalWarrantExercised" id="shpgf_AdjustmentsToAdditionalPaidInCapitalWarrantExercised" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="AdjustmentsToAdditionalPaidInCapitalWarrantExercisedShares" id="shpgf_AdjustmentsToAdditionalPaidInCapitalWarrantExercisedShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="ExchangeOfStockForStockDuringPeriodShares" id="shpgf_ExchangeOfStockForStockDuringPeriodShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="PriorYearAdjustment" id="shpgf_PriorYearAdjustment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestRestated" id="shpgf_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestRestated" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| <xsd:element name="IncomeAccessShareTrustFinancialStatementsTextBlock" id="shpgf_IncomeAccessShareTrustFinancialStatementsTextBlock" type="us-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/> |
| <xsd:element name="PaymentsToAcquireInterestInOtherSubsidiariesAndAffiliates" id="shpgf_PaymentsToAcquireInterestInOtherSubsidiariesAndAffiliates" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/> |
| </xsd:schema> |