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Shire plc – ‘10-K’ for 12/31/14 – ‘EX-21’

On:  Tuesday, 2/24/15, at 2:59pm ET   ·   For:  12/31/14   ·   Accession #:  950103-15-1422   ·   File #:  0-29630

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  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 2/24/15  Shire plc                         10-K       12/31/14  134:21M                                    Davis Polk & … LLP 01/FA

Annual Report   —   Form 10-K   —   Sect. 13 / 15(d) – SEA’34
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   2.79M 
 2: EX-21       Subsidiaries List                                   HTML     74K 
 3: EX-23.1     Consent of Experts or Counsel                       HTML     36K 
 4: EX-23.2     Consent of Experts or Counsel                       HTML     37K 
 5: EX-31.1     Certification -- §302 - SOA'02                      HTML     43K 
 6: EX-31.2     Certification -- §302 - SOA'02                      HTML     43K 
 7: EX-32.1     Certification -- §906 - SOA'02                      HTML     37K 
88: R1          Document and Entity Information                     HTML     65K 
66: R2          Consolidated Balance Sheets                         HTML    149K 
83: R3          Consolidated Balance Sheets (Parenthetical)         HTML     49K 
92: R4          Consolidated Statements of Income                   HTML    167K 
121: R5          Consolidated Statements of Income (Parenthetical)   HTML     48K  
70: R6          Consolidated Statements of Comprehensive Income     HTML     75K 
82: R7          Consolidated Statements of Comprehensive Income     HTML     38K 
                (Parenthetical)                                                  
59: R8          Consolidated Statements of Changes in Equity        HTML    130K 
47: R9          Consolidated Statements of Changes in Equity        HTML     51K 
                (Parenthetical)                                                  
123: R10         Consolidated Statements of Cash Flows               HTML    229K  
94: R11         Shire Income Access Share Trust Balance Sheet       HTML     57K 
93: R12         Shire Income Access Share Trust Statement of        HTML     44K 
                Income                                                           
101: R13         Shire Income Access Share Trust Statements of       HTML     61K  
                Changes in Equity                                                
102: R14         Shire Income Access Share Trust Statements of       HTML     80K  
                Cashflows                                                        
98: R15         Description of Operations                           HTML     38K 
103: R16         Summary of Significant Accounting Policies          HTML    130K  
84: R17         Business Combinations                               HTML    147K 
89: R18         Divestment of Product Rights                        HTML     41K 
96: R19         Reorganization Costs                                HTML     54K 
133: R20         Integration and acquisition costs                   HTML     40K  
112: R21         Accounts Receivable, Net                            HTML     48K  
76: R22         Inventories                                         HTML     42K 
95: R23         Results of discontinued operations                  HTML     51K 
79: R24         Prepaid Expenses and Other Current Assets           HTML     41K 
36: R25         Property, Plant and Equipment, Net                  HTML     46K 
114: R26         Goodwill                                            HTML     48K  
128: R27         Other Intangible Assets, Net                        HTML     61K  
53: R28         Accounts Payable and Accrued Expenses               HTML     45K 
52: R29         Other Current Liabilities                           HTML     41K 
57: R30         Borrowings                                          HTML     61K 
58: R31         Other Non-current Liabilities                       HTML     42K 
60: R32         Commitments and Contingencies                       HTML    102K 
24: R33         Accumulated Other Comprehensive Income              HTML     51K 
110: R34         Financial Instruments                               HTML     69K  
74: R35         Fair Value Measurement                              HTML    117K 
77: R36         Shareholders' Equity                                HTML     70K 
41: R37         Earnings Per Share                                  HTML     77K 
132: R38         Segmental Reporting                                 HTML     88K  
14: R39         Receipt of Break Fee                                HTML     41K 
63: R40         Retirement Benefits                                 HTML     40K 
119: R41         Taxation                                            HTML    145K  
38: R42         Related Parties                                     HTML     44K 
51: R43         Share-based Compensation Plans                      HTML    128K 
56: R44         Quarterly Results of Operations (Unaudited)         HTML     72K 
67: R45         Notes to the Shire Income Access Share Trust        HTML     46K 
                Financial Statements                                             
23: R46         Schedule II - Valuation and Qualifying Accounts     HTML     57K 
46: R47         Summary of Significant Accounting Policies          HTML    219K 
                (Policies)                                                       
17: R48         Business Combinations (Tables)                      HTML     70K 
117: R49         Reorganization costs (Table)                        HTML     46K  
37: R50         Accounts Receivable, Net (Tables)                   HTML     41K 
111: R51         Inventories (Tables)                                HTML     41K  
42: R52         Results of discontinued operations (Table)          HTML     45K 
64: R53         Prepaid Expenses and Other Current Assets (Tables)  HTML     41K 
16: R54         Property, Plant and Equipment, Net (Tables)         HTML     43K 
20: R55         Goodwill (Tables)                                   HTML     46K 
55: R56         Other Intangible Assets, Net (Tables)               HTML     54K 
28: R57         Accounts Payable and Accrued Expenses (Tables)      HTML     44K 
124: R58         Other Current Liabilities (Tables)                  HTML     40K  
72: R59         Other Non-current Liabilities (Tables)              HTML     41K 
99: R60         Commitments and Contingencies (Tables)              HTML     42K 
45: R61         Accumulated Other Comprehensive Income (Tables)     HTML     46K 
49: R62         Financial Instruments (Tables)                      HTML     50K 
108: R63         Fair Value Measurement (Tables)                     HTML    108K  
104: R64         Earnings Per Share (Tables)                         HTML     77K  
75: R65         Segmental Reporting (Tables)                        HTML     85K 
106: R66         Taxation (Tables)                                   HTML    128K  
43: R67         Share-based Compensation Plans (Tables)             HTML     99K 
80: R68         Quarterly Results of Operations (Tables)            HTML     69K 
127: R69         Summary of Significant Accounting Policies          HTML     71K  
                (Details)                                                        
19: R70         Business Combinations (ViroPharrma,NPS Pharma,      HTML    235K 
                Meritage) (Details)                                              
35: R71         Business Combinations (Pro Forma Information)       HTML     65K 
                (Details)                                                        
65: R72         Business Combinations (Lumena, Fibrotech and Other  HTML    209K 
                Acquisitions) (Details)                                          
26: R73         Divestment of Product Rights (Details)              HTML     47K 
131: R74         Reorganization Costs (Details)                      HTML     67K  
39: R75         Integration and acquisition costs (Details)         HTML     43K 
30: R76         Accounts Receivable, Net (Details)                  HTML     52K 
34: R77         Inventories (Details)                               HTML     48K 
21: R78         Results of discontinued operations (Details)        HTML     98K 
25: R79         Prepaid Expenses and Other Current Assets           HTML     50K 
                (Details)                                                        
90: R80         Property Plant and Equipment (Details)              HTML     59K 
32: R81         Goodwill (Details)                                  HTML     56K 
125: R82         Other Intangible Assets, Net (Details)              HTML     92K  
61: R83         Other Intangible Assets, Net (Roll Forward)         HTML     63K 
                (Details)                                                        
97: R84         Accounts Payable and Accrued Expenses (Details)     HTML     66K 
105: R85         Other Current Liabilities (Details)                 HTML     51K  
31: R86         Borrowings (Details)                                HTML    134K 
33: R87         Other Non-current Liabilities (Details)             HTML     52K 
122: R88         Commitments and Contingencies (Leases, and LC and   HTML     65K  
                Guarantees ) (Details)                                           
27: R89         Commitments and Contingencies (Collaborative        HTML     77K 
                Arrangements) (Details)                                          
91: R90         Commitments and Contingencies (Commitments and      HTML     66K 
                Loss Contingency) (Details)                                      
87: R91         Accumulated Other Comprehensive Income (Details)    HTML     66K 
109: R92         Financial Instruments (Interest Rate and Credit     HTML     82K  
                Risks) (Details)                                                 
86: R93         Financial Instruments (Foreign Exchange Risk and    HTML     63K 
                Its Classification on Balance Sheet) (Details)                   
71: R94         Financial Instruments (Foreign Exchange Risk and    HTML     39K 
                Its Effect on Income Statement) (Details)                        
116: R95         Fair Value Measurement (Assets and Liabilities      HTML     94K  
                That are Measured and Not Measured at Fair Value                 
                on a Recurring Basis) (Details)                                  
68: R96         Fair Value Measurement (Assets and Liabilities      HTML     89K 
                Measured at Fair Value on a Recurring Basis Using                
                Significant Unobservable Inputs) (Details)                       
40: R97         Fair Value Measurement (Quantitative Information    HTML    106K 
                About Recurring and Non-recurring Level 3 Fair                   
                Value Measurements) (Details)                                    
78: R98         Shareholders' Equity (Details)                      HTML    112K 
73: R99         Earnings Per Share (Details)                        HTML    159K 
54: R100        Segmental Reporting (Revenues and Long-lived        HTML     68K 
                Assets by Geographic Location) (Details)                         
134: R101        Segmental Reporting (Revenues and Accounts          HTML     67K  
                Receivable by Major Customers) (Details)                         
107: R102        Segmental Reporting (Revenue by Product) (Details)  HTML     78K  
85: R103        Receipt of Break Fee (Details)                      HTML     41K 
22: R104        Retirement Benefits (Details)                       HTML     37K 
118: R105        Taxation (Pretax Income from Continuing Operations  HTML    106K  
                and Provision for Income Taxes) (Details)                        
126: R106        Taxation (Effective Income Tax Rate                 HTML    152K  
                Reconciliation, and Statutory Tax Rates) (Details)               
120: R107        Taxation (Unrecognized Tax Benefits) (Details)      HTML     89K  
81: R108        Taxation (Deferred Tax Assets and Liabilities, and  HTML    126K 
                Valuation Allowances) (Details)                                  
29: R109        Taxation (Operating Loss and Tax Credit             HTML     80K 
                Carryforwards, and Their Expiration Dates)                       
                (Details)                                                        
100: R110        Related parties (Details)                           HTML     47K  
44: R111        Share-based Compensation Plans (Share-based         HTML     74K 
                Compensation Expense) (Details)                                  
15: R112        Share-based Compensation Plans (by Share-based      HTML     79K 
                Payment Award) (Details)                                         
69: R113        Share-based Compensation Plans (Stock Options and   HTML    129K 
                SARs) (Details)                                                  
62: R114        Share-based Compensation Plans (Performance Share   HTML     80K 
                Awards) (Details)                                                
113: R115        Share-based Compensation Plans (Fair Value          HTML     69K  
                Assumptions) (Details)                                           
48: R116        Quarterly Results of Operations (Details)           HTML    107K 
130: R117        Schedule II - Valuation and Qualifying Accounts     HTML     76K  
                (Details)                                                        
129: XML         IDEA XML File -- Filing Summary                      XML    218K  
18: EXCEL       IDEA Workbook of Financial Reports                  XLSX    310K 
50: EXCEL       IDEA Workbook of Financial Reports (.xls)            XLS   2.23M 
 8: EX-101.INS  XBRL Instance -- shpgf-20140930                      XML   3.82M 
10: EX-101.CAL  XBRL Calculations -- shpgf-20140930_cal              XML    381K 
11: EX-101.DEF  XBRL Definitions -- shpgf-20140930_def               XML   1.99M 
12: EX-101.LAB  XBRL Labels -- shpgf-20140930_lab                    XML   3.71M 
13: EX-101.PRE  XBRL Presentations -- shpgf-20140930_pre             XML   2.75M 
 9: EX-101.SCH  XBRL Schema -- shpgf-20140930                        XSD    401K 
115: ZIP         XBRL Zipped Folder -- 0000950103-15-001422-xbrl      Zip    397K  


‘EX-21’   —   Subsidiaries List


This Exhibit is an HTML Document rendered as filed.  [ Alternative Formats ]



EXHIBIT 21
 
LIST OF SUBSIDIARIES        
 
Subsidiary/undertaking
Jurisdiction of incorporation

 
Advanced BioHealing Corp
United States
Auralis Limited
United Kingdom
Bikam Pharmaceuticals, Inc.
United States
DuoCort Pharma AB
Sweden
Farboud Pty Ltd
Australia
FerroKin BioSciences, Inc.
United States
Fibrotech Therapeutics Pty Ltd
Australia
Jerini Ophthalmic Holding GmbH
Germany
Jerini Ophthalmic, Inc
United States
JPT Peptide Technologies Inc
United States
Lotus Tissue Repair Inc
United States
Lumena Pharma UK Limited
United Kingdom
Lumena Pharmaceuticals LLC
United States
Monmouth Pharmaceuticals Limited
United Kingdom
Movetis GmbH
Germany
Movetis Limited
United Kingdom
Pharma International Insurance Limited
Ireland
Premacure AB
Sweden and Luxembourg
Premacure Uppsala AB
Sweden
Rybar Laboratories Limited
United Kingdom
SARcode Bioscience Inc.
United States
SHGT Executive Services Inc.
United States
Shire (Shanghai) Pharmaceuticals Consultancy Co., Ltd.
China
Shire 2005 Investments Limited
Cayman Islands
Shire Acquisitions UK Limited
United Kingdom
Shire Australia Pty Limited
Australia
Shire Belgium BVBA
Belgium
Shire Biopharmaceuticals Holdings
United Kingdom
Shire Biopharmaceuticals Holdings Ireland Limited
Jersey
Shire Biopharmaceuticals Ireland Limited
Ireland
Shire Brandywine LLC
United States
Shire Pharma Canada ULC
Canada
Shire Central & Eastern Europe GmbH
Germany
Shire Colombia S.A.S
Colombia
Shire Czech S.R.O.
Czech Republic
Shire Denmark ApS
Denmark
Shire Deutschland GmbH
Germany
Shire Deutschland Investments GmbH
Germany
Shire Development LLC
United States
 
 
 
 

 
 
 
Shire Europe Finance
United Kingdom
Shire Europe Limited
United Kingdom
Shire Executive Services LLC
United States
Shire Farmacêutica Brasil LTDA
Brazil
Shire Finance Limited
Cayman Islands
Shire Finland Oy
Finland
Shire France S.A.
France
Shire Global Finance
United Kingdom
Shire Hellas Pharmaceuticals Import Export and Marketing S.A.
Greece
Shire Holdings Europe B.V.
Netherlands
Shire Holdings Europe Limited
United Kingdom
Shire Holdings Europe No.2 S.a.r.l.
Luxembourg
Shire Holdings Ireland
Ireland
Shire Holdings Ireland No.2 Limited
Ireland
Shire Holdings Limited
Bermuda
Shire Holdings Luxembourg S.a r.l.
Luxembourg
Shire Holdings UK Canada Limited
United Kingdom
Shire Holdings UK Limited
United Kingdom
Shire Holdings US AG
United States
Shire Human Genetic Therapies (Canada) Inc.
Canada
Shire Human Genetic Therapies AB
Sweden
Shire Human Genetic Therapies Limited
United Kingdom
Shire Human Genetic Therapies S.A.
Argentina
Shire Human Genetic Therapies Securities Corporation
United States
Shire Human Genetic Therapies UK Limited
United Kingdom
Shire Human Genetic Therapies, Inc
United States
SHIRE ILAC TICARET LIMITED SIRKETI / Shire Pharmaceuticals Trading Limited Company
Turkey
Shire Incorporated
United States
Shire Intellectual Property 2 SRL
Barbados
Shire Intellectual Property Ireland Limited
Ireland
Shire Intellectual Property SRL
Barbados
Shire International GmbH
Switzerland
Shire International Licensing BV
Netherlands
Shire International Licensing VOF
Netherlands
Shire Investments & Finance (U.K.) Company
United Kingdom
Shire IP Services Corporation
Canada
Shire Ireland Finance Limited
Ireland
Shire Ireland Investment Limited
Ireland
Shire Ireland Premacure Investment
Ireland
Shire Italia S.p.A.
Italy
Shire Japan KK
Japan
 
 
 
 

 
 
 
Shire Jersey Limited
Jersey
Shire LLC
United States
Shire Luxembourg Finance S.a.r.l.
Luxembourg
Shire Luxembourg Intellectual Property No.2 S.a r.l.
Luxembourg
Shire Luxembourg Intellectual Property No.3 S.a.r.l.
Luxembourg
Shire Luxembourg Intellectual Property S.a r.l.
Luxembourg
Shire Luxembourg Sarl
Luxembourg
Shire North American Group Inc.
United States
Shire Norway AS
Norway
Shire Orphan and Rare Diseases GmbH
Switzerland
Shire Orphan Therapies GmbH
Germany
Shire Orphan Therapies, Inc.
United States
Shire Pharma Korea Yuhan Hoesa
Korea, Republic of
Shire Pharmaceutical Contracts Limited
United Kingdom
Shire Pharmaceutical Development Inc
United States
Shire Pharmaceutical Development Limited
United Kingdom
Shire Pharmaceutical Holdings Ireland Limited
Ireland
Shire Pharmaceutical Investment Trading Ireland
Ireland
Shire Pharmaceutical Investments 2008
Ireland
Shire Pharmaceuticals Group
United Kingdom
Shire Pharmaceuticals Iberica S.L.
Spain
Shire Pharmaceuticals International
Ireland
Shire Pharmaceuticals Investments (British Virgin Islands) Limited
Virgin Islands, British
Shire Pharmaceuticals Investments 2007
Ireland
Shire Pharmaceuticals Ireland Limited
Ireland
Shire Pharmaceuticals Limited
United Kingdom
Shire Pharmaceuticals LLC
United States
Shire Pharmaceuticals Mexico SA de CV
Mexico
Shire Pharmaceuticals Portugal, Lda
Portugal
Shire Pharmaceuticals Services Limited
United Kingdom
Shire Polska Sp. z o. o.
Poland
Shire Properties US
United States
Shire Regenerative Medicine LLC
United States
Shire Regulatory Inc
United States
Shire Rus Limited Liability Company
Russian Federation
Shire Singapore Pte. Ltd.
Singapore
Shire Supplies U.S. LLC
United States
Shire Sweden AB
Sweden
Shire Sweden Holdings S.a.r.l
Luxembourg
Shire UK Investments Limited
United Kingdom
Shire US Holdings LLC
United States
 
 
 
 

 
 
 
Shire US Inc
United States
Shire US Investment Inc
United States
Shire US Investments
United Kingdom
Shire US Manufacturing Inc
United States
Shire ViroPharma Incorporated
United States
Shire-Movetis NV
Belgium
Sparkleflame Limited
United Kingdom
Tanaud International BV
Netherlands
Tanaud Ireland Inc.
Ireland
The Endocrine Centre Limited
United Kingdom
VCO Incorporated
United States
ViroPharma AB
Sweden
Viropharma Biologics Inc
United States
Viropharma Canada Incorporated
Canada
Viropharma GmbH
Germany
Viropharma Holdings Limited
Bermuda
Viropharma Holdings LLC
United States
Viropharma Limited
United Kingdom
ViroPharma LLC
Switzerland
Viropharma Pty Ltd
Australia
Viropharma Puerto Rico Inc
Puerto Rico
Viropharma S.r.l
Italy
Viropharma SAS
France
Viropharma Spain SL
Spain
Viropharma SPRL
Belgium
Viropharma Sweden AB
Sweden
VPDE Incorporated
United States
VPINT Incorporated
United States
VPMP Incorporated
United States

 
All subsidiary undertakings of Shire plc are beneficially owned (directly or indirectly) as to 100% and are all consolidated in the consolidated financial statements of Shire plc.
 
 
 
 

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Filing Submission 0000950103-15-001422   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)

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