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Opko Health, Inc. – ‘10-K’ for 12/31/17 – ‘EX-10.28’

On:  Thursday, 3/1/18, at 4:09pm ET   ·   For:  12/31/17   ·   Accession #:  944809-18-14   ·   File #:  1-33528

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  As Of               Filer                 Filing    For·On·As Docs:Size

 3/01/18  Opko Health, Inc.                 10-K       12/31/17  111:16M

Annual Report   —   Form 10-K   —   Sect. 13 / 15(d) – SEA’34
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   1.56M 
 2: EX-10.26    Material Contract                                   HTML    353K 
 3: EX-10.27    Material Contract                                   HTML     64K 
 4: EX-10.28    Material Contract                                   HTML     55K 
 5: EX-10.29    Material Contract                                   HTML     82K 
 6: EX-21       Subsidiaries List                                   HTML     32K 
 7: EX-23.1     Consent of Experts or Counsel                       HTML     32K 
 8: EX-31.1     Certification -- §302 - SOA'02                      HTML     36K 
 9: EX-31.2     Certification -- §302 - SOA'02                      HTML     36K 
10: EX-32.1     Certification -- §906 - SOA'02                      HTML     30K 
11: EX-32.2     Certification -- §906 - SOA'02                      HTML     30K 
18: R1          Document and Entity Information                     HTML     56K 
19: R2          Consolidated Balance Sheets                         HTML    108K 
20: R3          Consolidated Balance Sheets (Parenthetical)         HTML     38K 
21: R4          Consolidated Statements of Operations               HTML     98K 
22: R5          Consolidated Statements of Comprehensive Loss       HTML     53K 
23: R6          Consolidated Statements of Equity                   HTML    130K 
24: R7          Consolidated Statements of Cash Flows               HTML    172K 
25: R8          Consolidated Statements of Cash Flows               HTML     32K 
                (Parenthetical)                                                  
26: R9          Business and Organization                           HTML     36K 
27: R10         Summary of Significant Accounting Policies          HTML    118K 
28: R11         Loss Per Share                                      HTML     36K 
29: R12         Acquisitions, Investments, and Licenses             HTML     74K 
30: R13         Composition of Certain Financial Statement          HTML    302K 
                Captions                                                         
31: R14         Debt                                                HTML    168K 
32: R15         Shareholders' Equity                                HTML     47K 
33: R16         Accumulated Other Comprehensive Income (Loss)       HTML     62K 
34: R17         Equity-Based Compensation                           HTML     80K 
35: R18         Income Taxes                                        HTML    155K 
36: R19         Related Party Transactions                          HTML     43K 
37: R20         Employee Benefit Plans                              HTML     32K 
38: R21         Commitments and Contingencies                       HTML     43K 
39: R22         Strategic Alliances                                 HTML     66K 
40: R23         Leases                                              HTML     52K 
41: R24         Segments                                            HTML    144K 
42: R25         Fair Value Measurements                             HTML    158K 
43: R26         Derivative Contracts                                HTML     58K 
44: R27         Selected Quarterly Financial Data (Unaudited)       HTML     74K 
45: R28         Subsequent Events                                   HTML     35K 
46: R29         Summary of Significant Accounting Policies          HTML    181K 
                (Policies)                                                       
47: R30         Summary of Significant Accounting Policies          HTML     54K 
                (Tables)                                                         
48: R31         Acquisitions, Investments, and Licenses (Tables)    HTML     56K 
49: R32         Composition of Certain Financial Statement          HTML    307K 
                Captions (Tables)                                                
50: R33         Debt (Tables)                                       HTML    148K 
51: R34         Shareholders' Equity (Tables)                       HTML     43K 
52: R35         Accumulated Other Comprehensive Income (Loss)       HTML     60K 
                (Tables)                                                         
53: R36         Equity-Based Compensation (Tables)                  HTML     68K 
54: R37         Income Taxes (Tables)                               HTML    148K 
55: R38         Leases (Tables)                                     HTML     56K 
56: R39         Segments (Tables)                                   HTML    144K 
57: R40         Fair Value Measurements (Tables)                    HTML    159K 
58: R41         Derivative Contracts (Tables)                       HTML     59K 
59: R42         Selected Quarterly Financial Data (Unaudited)       HTML     74K 
                (Tables)                                                         
60: R43         Business and Organization (Details)                 HTML     43K 
61: R44         Summary of Significant Accounting Policies          HTML    162K 
                (Details)                                                        
62: R45         Summary of Significant Accounting Policies -        HTML     53K 
                Schedule of Product Sales Allowances and Accruals                
                (Details)                                                        
63: R46         Loss Per Share - Narrative (Details)                HTML     40K 
64: R47         Acquisitions, Investments, and Licenses -           HTML    181K 
                Narrative (Details)                                              
65: R48         Acquisitions, Investments, and Licenses -           HTML     52K 
                Transition Therapeutics Purchase Price Allocation                
                (Details) (Details)                                              
66: R49         Acquisitions, Investments, and Licenses - Summary   HTML     46K 
                of Investments (Details)                                         
67: R50         Composition of Certain Financial Statement          HTML    171K 
                Captions (Details)                                               
68: R51         Composition of Certain Financial Statement          HTML    290K 
                Captions - Fair Value Assigned to Intangible Asset               
                Classes (Details)                                                
69: R52         Composition of Certain Financial Statement          HTML     36K 
                Captions - Narrative (Details)                                   
70: R53         Composition of Certain Financial Statement          HTML     48K 
                Captions - Changes in Allowance for Doubtful                     
                Accounts, Provision for Inventory Reserve and Tax                
                Valuation (Details)                                              
71: R54         Composition of Certain Financial Statement          HTML     73K 
                Captions - Changes in Goodwill (Detail)                          
72: R55         Debt - Narrative (Details)                          HTML    174K 
73: R56         Debt - Notes (Details)                              HTML     71K 
74: R57         Debt - Inputs Used In Lattice Model (Details)       HTML     46K 
75: R58         Debt - Lines Of Credit (Details)                    HTML     70K 
76: R59         Debt - Mortgage Notes And Other Debt (Details)      HTML     39K 
77: R60         Shareholders' Equity - Narrative (Details)          HTML     59K 
78: R61         Shareholders' Equity (Details)                      HTML     45K 
79: R62         Accumulated Other Comprehensive Income (Loss)       HTML     51K 
                (Details)                                                        
80: R63         Equity-Based Compensation - Narrative (Details)     HTML     80K 
81: R64         Equity-Based Compensation - Option-Pricing Formula  HTML     48K 
                (Details)                                                        
82: R65         Equity-Based Compensation - Summary of Option       HTML     83K 
                Activity (Details)                                               
83: R66         Income Taxes - Benefits (Provision) for Income      HTML     57K 
                Taxes (Details)                                                  
84: R67         Income Taxes - Deferred Income Taxes (Details)      HTML     93K 
85: R68         Income Taxes - Change in Gross Unrecognized Income  HTML     41K 
                (Details)                                                        
86: R69         Income Taxes - Narrative (Details)                  HTML     74K 
87: R70         Income Taxes - Difference in Federal and Effective  HTML     60K 
                Tax Rate (Details)                                               
88: R71         Income Taxes - Reconciliation Losses Before Tax,    HTML     36K 
                US and Foreign Jurisdictions (Details)                           
89: R72         Related Party Transactions - Narrative (Details)    HTML    192K 
90: R73         Employee Benefit Plans (Details)                    HTML     38K 
91: R74         Commitments and Contingencies (Details)             HTML     63K 
92: R75         Strategic Alliances (Details)                       HTML    125K 
93: R76         Leases (Details)                                    HTML     32K 
94: R77         Leases - Schedule of Maturities of Operating        HTML     48K 
                Leases (Details)                                                 
95: R78         Leases - Schedule of Capital Leases (Details)       HTML     35K 
96: R79         Leases - Schedule of Maturities of Capital Leases   HTML     56K 
                (Details)                                                        
97: R80         Segments - Narrative (Details)                      HTML     57K 
98: R81         Segments - Operating Segments (Details)             HTML    102K 
99: R82         Segments - Reconciliation Property Plant and        HTML     36K 
                Equipment, US and Foreign Jurisdictions (Details)                
100: R83         Fair Value Measurements - Summary Of Investments    HTML     40K  
                (Details)                                                        
101: R84         Fair Value Measurements - Assets And Liabilities    HTML     81K  
                Measured At Fair Value (Details)                                 
102: R85         Fair Value Measurements - Notes (Details)           HTML     37K  
103: R86         Fair Value Measurements - Level 3 Reconciliation    HTML     46K  
                (Details)                                                        
104: R87         Fair Value Measurements - Narrative (Details)       HTML     40K  
105: R88         Derivative Contracts - Fair Value and Presentation  HTML     47K  
                (Details)                                                        
106: R89         Derivative Contracts - Losses and Gains on          HTML     40K  
                Derivative Instruments (Details)                                 
107: R90         Selected Quarterly Financial Data (Unaudited)       HTML     51K  
                (Details)                                                        
108: R91         Subsequent Events (Details)                         HTML     47K  
110: XML         IDEA XML File -- Filing Summary                      XML    193K  
109: EXCEL       IDEA Workbook of Financial Reports                  XLSX    157K  
12: EX-101.INS  XBRL Instance -- opk-20171231                        XML   5.01M 
14: EX-101.CAL  XBRL Calculations -- opk-20171231_cal                XML    377K 
15: EX-101.DEF  XBRL Definitions -- opk-20171231_def                 XML   1.42M 
16: EX-101.LAB  XBRL Labels -- opk-20171231_lab                      XML   2.99M 
17: EX-101.PRE  XBRL Presentations -- opk-20171231_pre               XML   1.86M 
13: EX-101.SCH  XBRL Schema -- opk-20171231                          XSD    267K 
111: ZIP         XBRL Zipped Folder -- 0000944809-18-000014-xbrl      Zip    453K  


‘EX-10.28’   —   Material Contract


This Exhibit is an HTML Document rendered as filed.  [ Alternative Formats ]



 <!   C:   C: 
  Exhibit  

EXECUTION VERSION


AMENDMENT NO. 6 TO CREDIT AGREEMENT
AMENDMENT NO. 6 TO CREDIT AGREEMENT (this “Amendment”), dated as of December 22, 2017, is entered into among BIO-REFERENCE LABORATORIES, INC., a New Jersey corporation (“Company”), the Subsidiary Borrowers party hereto (“Subsidiary Borrowers,” and together with Company, each a “Borrower” and, collectively, the “Borrowers”), the other Loan Parties party hereto, the Lenders party hereto, and JPMORGAN CHASE BANK, N.A., as the administrative agent for the Lenders (the “Administrative Agent”).

W I T N E S S E T H :
WHEREAS, the Borrowers, the other Loan Parties party thereto, the Lenders party thereto, and the Administrative Agent have executed and delivered that certain Credit Agreement dated as of November 5, 2015, as amended by Amendment No. 1 to Credit Agreement dated as of February 29, 2016, as amended by Amendment No. 2 to Credit Agreement dated as of September 26, 2016, as amended by Amendment No. 3 to Credit Agreement dated as of March 17, 2017, as amended by Amendment No. 4 to Credit Agreement dated as of August 7, 2017, and as amended by Amendment No. 5 to Credit Agreement dated as of November 8, 2017 (as further amended, restated, supplemented, or otherwise modified from time to time prior to the date hereof, the “Credit Agreement”); and

WHEREAS, the Borrowers have requested that the Lenders and the Administrative Agent make certain amendments to the Credit Agreement, and the Lenders party hereto, constituting all Lenders under the Credit Agreement, have agreed to such amendments, subject to the terms and conditions hereof.
NOW, THEREFORE, for and in consideration of the above premises and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged by the parties hereto, each of the Borrowers, the other Loan Parties, the Lenders and the Administrative Agent hereby covenant and agree as follows:
SECTION 1. Definitions. Unless otherwise specifically defined herein, each term used herein (and in the recitals above) which is defined in the Credit Agreement shall have the meaning assigned to such term in the Credit Agreement. As of the date hereof, each reference in the Credit Agreement to “this Agreement,” “hereunder,” “hereof,” “herein,” or words of like import, and each reference in the other Loan Documents to the Credit Agreement (including, without limitation, by means of words like “thereunder,” “thereof” and words of like import), shall mean and be a reference to the Credit Agreement, as amended hereby.
SECTION 2.     Amendments to Credit Agreement. Effective as of the Amendment No. 6 Effective Date (as defined below), the Credit Agreement is hereby amended as follows:
(a)     Amendments to Section 1.01.
(i)     Section 1.01 of the Credit Agreement is hereby amended by adding the following definition in appropriate alphabetical order:

NAI-1503292713v1


Amendment No. 6 Effective Date” means December 22, 2017.
(ii)     Section 1.01 of the Credit Agreement is amended by replacing the definition of “Special Intercompany Loans” with the following:
Special Intercompany Loans” means (i) a loan made within ten (10) days of the Amendment No. 3 Effective Date by the Company to the Parent in an amount not to exceed $55,000,000, (ii) a loan made on the Amendment No. 4 Effective Date by the Company to the Parent in an amount not to exceed $35,000,000, (iii) a loan made on October 11, 2017 by the Company to the Parent in an amount not to exceed $25,000,000, and (iv) a loan made within ten (10) days of the Amendment No. 6 Effective Date by the Company to the Parent in an amount not to exceed $20,000,000.
(b)     Section 6.04(d) of the Credit Agreement is amended so that it reads, in its entirety, as follows:
(d)    (i) loans or advances made by any Loan Party to any Subsidiary and made by any Subsidiary to a Loan Party or any other Subsidiary, provided that (A) any such loans and advances made by a Loan Party to a Subsidiary that is not a Loan Party shall be evidenced by a promissory note pledged pursuant to the Security Agreement and (B) the amount of such loans and advances made by Loan Parties to Subsidiaries that are not Loan Parties (together with outstanding investments permitted under clause (B) to the proviso to Section 6.04(c) and outstanding Guarantees permitted under the proviso to Section 6.04(e) and excluding any Special Intercompany Loan) shall not exceed $5,000,000 at any time outstanding (in each case determined without regard to any write-downs or write-offs) and (ii) the Special Intercompany Loans, provided that (x) each Special Intercompany Loan shall be evidenced by a promissory note pledged pursuant to the Security Agreement and (y) the original promissory notes evidencing the Special Intercompany Loans referenced in clauses (iii) and (iv) of the definition of “Special Intercompany Loans” shall be delivered to the Administrative Agent within thirty (30) days (or such later date as agreed to by the Administrative Agent in its sole discretion) after the Amendment No. 6 Effective Date;
SECTION 3.     Conditions Precedent. This Amendment shall become effective on the date (such date, the “Amendment No. 6 Effective Date”) the following conditions precedent shall have been satisfied:
(a)     receipt by the Administrative Agent of signatures to this Amendment from the parties listed on the signature pages hereto; and
(b)     the Administrative Agent shall have received from the Borrowers (or the Administrative Agent shall be satisfied with arrangements made for the payment thereof) all other costs, fees, and expenses owed by the Borrowers to the Administrative Agent in connection with this Amendment, including, without limitation, reasonable attorneys’ fees and expenses, in accordance with Section 9.03 of the Credit Agreement.

NAI-1503292713v1    2


SECTION 4.     Miscellaneous.
(a)     Representations and Warranties. To induce the Administrative Agent and Lenders to enter into this Amendment, the Borrowers hereby represent and warrant to the Administrative Agent and the Lenders that all representations and warranties of the Borrowers contained in Article III of the Credit Agreement or any other Loan Document are true and correct in all material respects with the same effect as though made on and as of the Amendment No. 6 Effective Date (except with respect to representations and warranties made as of an expressed date, which representations and warranties are true and correct in all material respects as of such date).
(b)     No Offset. To induce the Administrative Agent and Lenders to enter into this Amendment, the Borrowers hereby acknowledge and agree that, as of the date hereof, and after giving effect to the terms hereof, there exists no right of offset, defense, counterclaim, claim, or objection in favor of the Borrowers or arising out of or with respect to any of the loans or other obligations of the Borrowers owed by the Borrowers under the Credit Agreement or any other Loan Document.
(c)     Loan Document. The parties hereto hereby acknowledge and agree that this Amendment is a Loan Document.
(d)     Effect of Amendment. Except as set forth expressly hereinabove and in Section 4(m) below, all terms of the Credit Agreement and the other Loan Documents shall be and remain in full force and effect, and shall constitute the legal, valid, binding, and enforceable obligations of the Borrowers, enforceable in accordance with their terms, subject to applicable bankruptcy, insolvency, reorganization, moratorium or other laws affecting creditors’ rights generally and subject to general principles of equity, regardless of whether considered in a proceeding in equity or at law.
(e)     No Novation or Mutual Departure. The Borrowers expressly acknowledge and agree that (i) this Amendment does not constitute or establish, a novation with respect to the Credit Agreement or any of the other Loan Documents, or a mutual departure from the strict terms, provisions, and conditions thereof, other than with respect to the amendments set forth in Section 2 above and the limited waiver set forth in Section 4(m) below, and (ii) nothing in this Amendment shall affect or limit the Administrative Agent’s or any Lender’s right to (x) demand payment of the Obligations under, or demand strict performance of the terms, provisions and conditions of, the Credit Agreement and the other Loan Documents (in each case, as amended hereby and subject to the limited waiver set forth in Section 4(m) below), as applicable, (y) exercise any and all rights, powers, and remedies under the Credit Agreement or the other Loan Documents (in each case, as amended hereby and subject to the limited waiver set forth in Section 4(m) below) or at law or in equity, or (z) do any and all of the foregoing, immediately at any time during the occurrence of an Event of Default and in each case, in accordance with the terms and provisions of the Credit Agreement and the other Loan Documents.
(f)     Counterparts. This Amendment may be executed in any number of counterparts and by different parties hereto in separate counterparts, each of which when so executed and delivered shall be deemed to be an original and all of which counterparts, taken together, shall constitute but one and the same instrument. This Amendment may be executed by each party on separate copies,

NAI-1503292713v1    3


which copies, when combined so as to include the signatures of all parties, shall constitute a single counterpart of this Amendment.
(g)     Fax or Other Transmission. Delivery by one or more parties hereto of an executed counterpart of this Amendment via facsimile, telecopy, or other electronic method of transmission pursuant to which the signature of such party can be seen (including, without limitation, Adobe Corporation’s Portable Document Format) shall have the same force and effect as the delivery of an original executed counterpart of this Amendment. Any party delivering an executed counterpart of this Amendment by facsimile or other electronic method of transmission shall also deliver an original executed counterpart, but the failure to do so shall not affect the validity, enforceability, or binding effect of this Amendment.
(h)     Recitals Incorporated Herein. The preamble and the recitals to this Amendment are hereby incorporated herein by this reference.
(i)     Section References. Section titles and references used in this Amendment shall be without substantive meaning or content of any kind whatsoever and are not a part of the agreements among the parties hereto evidenced hereby.
(j)     Governing Law. This Amendment shall be governed by and construed in accordance with the internal laws (and not the law of conflicts) of the State of New York, but giving effect to federal laws applicable to national banks.
(k)     Severability. Any provision of this Amendment which is prohibited or unenforceable shall be ineffective to the extent of such prohibition or unenforceability without invalidating the remaining provisions hereof in that jurisdiction or affecting the validity or enforceability of such provision in any other jurisdiction.
(l)     Reaffirmation of Loan Parties. Each Loan Party (i) consents to the execution and delivery of this Amendment, (ii) reaffirms all of its obligations and covenants under the Loan Documents (including, without limitation, the Collateral Documents and the Loan Guaranty) to which it is a party, and (iii) agrees that, except to the extent amended hereby, none of its respective obligations and covenants under the Loan Documents shall be reduced or limited by the execution and delivery of this Amendment.
(m)     Waiver by Lenders of Certain Items. Subject to the satisfaction of the conditions precedent set forth in Section 3 above, the Lenders hereby waive any Default or Event of Default that has occurred and is continuing as of the date hereof solely as a result of the Company making the Special Intercompany Loan referenced in clause (iii) of the definition of “Special Intercompany Loans”. This waiver is an accommodation, and the Loan Parties acknowledge and agree that the Lenders shall require strict compliance with the Credit Agreement, as amended by this Amendment, hereafter.
[SIGNATURES ON FOLLOWING PAGES.]


NAI-1503292713v1    4


IN WITNESS WHEREOF, the Borrowers, the other Loan Parties, the Administrative Agent and the Lenders have caused this Amendment to be duly executed by their respective duly authorized officers as of the day and year first above written.
BORROWERS:
 
 
 
BIO-REFERENCE LABORATORIES, INC.
GENEDX, INC.
FLORIDA CLINICAL LABORATORY, INC.
MERIDIAN CLINICAL LABORATORY CORP.
 
 
 
 
By:
 
Name:
 
Title:
Director, Vice President
 
 
 
 
 
 
 
 
 
 
 
 
OTHER LOAN PARTIES:
 
 
 
CAREEVOLVE.COM, INC.
BRLI-GENPATH DIAGNOSTICS, INC.
GENEDX MENA LLC
 
 
 
 
 
 
By:
 
Name:
 
Title:
Director, Vice President
 
 
 



[BRLI – Amendment No. 6 to Credit Agreement]
NAI-1503292713v1



JPMORGAN CHASE BANK, N.A.,
Individually as a Lender and as Administrative
Agent, Issuing Bank and Swingline Lender
 
 
 
 
By:
 
Name:
 
Title:
Authorized Officer




[BRLI – Amendment No. 6 to Credit Agreement]
NAI-1503292713v1

Dates Referenced Herein   and   Documents Incorporated by Reference

This ‘10-K’ Filing    Date    Other Filings
Filed on:3/1/184,  8-K,  8-K/A
For Period end:12/31/17
12/22/178-K
11/8/1710-Q,  8-K
10/11/17
8/7/17
3/17/174,  8-K
9/26/164,  CT ORDER
2/29/1610-K,  4,  8-K
11/5/154,  8-K,  8-K/A
 List all Filings 


7 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 2/27/23  Opko Health, Inc.                 10-K       12/31/22  121:20M
 3/01/22  Opko Health, Inc.                 10-K       12/31/21  110:16M
 2/18/21  Opko Health, Inc.                 10-K       12/31/20  111:16M
12/26/18  SEC                               UPLOAD2/21/19    2:39K  Opko Health, Inc.
11/19/18  SEC                               UPLOAD2/21/19    2:54K  Opko Health, Inc.
 9/13/18  SEC                               UPLOAD2/21/19    2:44K  Opko Health, Inc.
 8/03/18  SEC                               UPLOAD2/21/19    2:48K  Opko Health, Inc.
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