SEC Info℠  
    Home      Search      My Interests      Help      Sign In      Please Sign In

Y-mAbs Therapeutics, Inc. – ‘10-K’ for 12/31/22 – ‘EX-101.CAL’

On:  Thursday, 3/30/23, at 4:01pm ET   ·   For:  12/31/22   ·   Accession #:  1558370-23-5073   ·   File #:  1-38650

Previous ‘10-K’:  ‘10-K’ on 3/1/22 for 12/31/21   ·   Next & Latest:  ‘10-K’ on 2/29/24 for 12/31/23   ·   17 References:   

Find Words in Filings emoji
 		  in    Show  and   ↓Hints

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/30/23  Y-mAbs Therapeutics, Inc.         10-K       12/31/22  106:10M                                    Toppan Merrill Bridge/FA

Annual Report   —   Form 10-K

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   2.63M 
 2: EX-4.4      Instrument Defining the Rights of Security Holders  HTML     50K 
 3: EX-10.41    Material Contract                                   HTML     39K 
 4: EX-10.42    Material Contract                                   HTML    325K 
 5: EX-21.1     Subsidiaries List                                   HTML     28K 
 6: EX-23       Consent of Expert or Counsel                        HTML     28K 
 7: EX-31.1     Certification -- §302 - SOA'02                      HTML     36K 
 8: EX-31.2     Certification -- §302 - SOA'02                      HTML     35K 
 9: EX-32.1     Certification -- §906 - SOA'02                      HTML     31K 
10: EX-32.2     Certification -- §906 - SOA'02                      HTML     31K 
16: R1          Document and Entity Information                     HTML     97K 
17: R2          Consolidated Balance Sheets                         HTML    123K 
18: R3          Consolidated Balance Sheets (Parenthetical)         HTML     44K 
19: R4          Consolidated Statements of Net Income (Loss) and    HTML     98K 
                Comprehensive Income (Loss)                                      
20: R5          Consolidated Statements of Changes in               HTML     79K 
                Stockholders' Equity                                             
21: R6          Consolidated Statements of Cash Flows               HTML    103K 
22: R7          Organization and Description of Business            HTML     32K 
23: R8          Basis of Presentation                               HTML     36K 
24: R9          Summary of Significant Accounting Policies          HTML    115K 
25: R10         Product Revenue                                     HTML     62K 
26: R11         Net Loss Per Share                                  HTML     42K 
27: R12         Inventories                                         HTML     60K 
28: R13         Intangible Assets, Net                              HTML     32K 
29: R14         Accrued Liabilities                                 HTML     46K 
30: R15         License Agreements and Commitments                  HTML    164K 
31: R16         Stockholders' Equity                                HTML     41K 
32: R17         Share-Based Compensation                            HTML    110K 
33: R18         Related Party Transactions                          HTML     32K 
34: R19         Income Taxes                                        HTML    126K 
35: R20         Other Benefits                                      HTML     31K 
36: R21         Gain From Sale of Priority Review Voucher           HTML     31K 
37: R22         Subsequent Events                                   HTML     32K 
38: R23         Summary of Significant Accounting Policies          HTML    164K 
                (Policies)                                                       
39: R24         Summary of Significant Accounting Policies          HTML     74K 
                (Tables)                                                         
40: R25         Product Revenue (Tables)                            HTML     56K 
41: R26         Net Loss Per Share (Tables)                         HTML     40K 
42: R27         Inventories (Tables)                                HTML     59K 
43: R28         Accrued Liabilities (Tables)                        HTML     46K 
44: R29         License Agreements and Commitments (Tables)         HTML    132K 
45: R30         Share-Based Compensation (Tables)                   HTML    101K 
46: R31         Income Taxes (Tables)                               HTML    129K 
47: R32         BASIS OF PRESENTATION - Accumulated deficit         HTML     32K 
                (Details)                                                        
48: R33         BASIS OF PRESENTATION - Public offering (Details)   HTML     41K 
49: R34         BASIS OF PRESENTATION - Cash and cash equivalents   HTML     31K 
                (Details)                                                        
50: R35         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     36K 
                Concentration of Credit Risk (Details)                           
51: R36         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     30K 
                Inventory (Details)                                              
52: R37         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Fair   HTML     46K 
                Value Measurement (Details)                                      
53: R38         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     30K 
                Operating Leases (Details)                                       
54: R39         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     30K 
                Revenue Recognition - Product revenue (Details)                  
55: R40         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     65K 
                Revenue Recognition - License revenue (Details)                  
56: R41         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     30K 
                Segment (Details)                                                
57: R42         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     44K 
                Property and Equipment (Details)                                 
58: R43         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     30K 
                Income Taxes (Details)                                           
59: R44         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES -        HTML     31K 
                Research and development (Details)                               
60: R45         SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Other  HTML     33K 
                policies (Details)                                               
61: R46         PRODUCT REVENUE - Disaggregation (Details)          HTML     41K 
62: R47         PRODUCT REVENUE - Discounts and Allowances          HTML     71K 
                (Details)                                                        
63: R48         PRODUCT REVENUE - Concentrations (Details)          HTML     44K 
64: R49         NET LOSS PER SHARE - Basic and diluted (Details)    HTML     56K 
65: R50         NET LOSS PER SHARE - Anti-dilutive securities       HTML     30K 
                (Details)                                                        
66: R51         Inventories (Details)                               HTML     51K 
67: R52         Intangible Assets, Net (Details)                    HTML     68K 
68: R53         Accrued Liabilities (Details)                       HTML     42K 
69: R54         LICENSE AGREEMENTS AND COMMITMENTS - MSK License    HTML     57K 
                (Details)                                                        
70: R55         LICENSE AGREEMENTS AND COMMITMENTS - LCD33 License  HTML     44K 
                (Details)                                                        
71: R56         LICENSE AGREEMENTS AND COMMITMENTS - MabVax/MSK     HTML     36K 
                License (Details)                                                
72: R57         LICENSE AGREEMENTS AND COMMITMENTS - SADA License   HTML     38K 
                Agreement (Details)                                              
73: R58         LICENSE AGREEMENTS AND COMMITMENTS - Summary of     HTML     69K 
                Significant Agreements and Commitments (Details)                 
74: R59         LICENSE AGREEMENTS AND COMMITMENTS - Other          HTML     47K 
                agreements (Details)                                             
75: R60         LICENSE AGREEMENTS AND COMMITMENTS - Lease          HTML     68K 
                agreements (Details)                                             
76: R61         LICENSE AGREEMENTS AND COMMITMENTS - Lease costs    HTML     37K 
                (Details)                                                        
77: R62         LICENSE AGREEMENTS AND COMMITMENTS - Lease          HTML     46K 
                maturities (Details)                                             
78: R63         LICENSE AGREEMENTS AND COMMITMENTS - Lease term     HTML     33K 
                and discount rate (Details)                                      
79: R64         LICENSE AGREEMENTS AND COMMITMENTS - Severance      HTML     37K 
                Related Benefits (Details)                                       
80: R65         LICENSE AGREEMENTS AND COMMITMENTS - Legal matters  HTML     35K 
                (Details)                                                        
81: R66         STOCKHOLDERS' EQUITY - Authorized, Common and       HTML     47K 
                Preferred Stock (Details)                                        
82: R67         STOCKHOLDERS' EQUITY - Stock grant agreements with  HTML     83K 
                non-employees (Details)                                          
83: R68         STOCKHOLDERS' EQUITY - Issuance of common stock     HTML     42K 
                (Details)                                                        
84: R69         SHARE-BASED COMPENSATION - 2015 Plan (Details)      HTML     37K 
85: R70         SHARE-BASED COMPENSATION - 2018 Plan (Details)      HTML     54K 
86: R71         SHARE-BASED COMPENSATION - Stock-based              HTML     40K 
                compensation expense - Options (Details)                         
87: R72         SHARE-BASED COMPENSATION - Stock Option Valuation   HTML     37K 
                (Details)                                                        
88: R73         SHARE-BASED COMPENSATION - Stock option activity    HTML     67K 
                (Details)                                                        
89: R74         SHARE-BASED COMPENSATION - Stock option grants      HTML     58K 
                (Details)                                                        
90: R75         SHARE-BASED COMPENSATION - Stock option             HTML     35K 
                unrecognized compensation (Details)                              
91: R76         SHARE-BASED COMPENSATION - Restricted Stock Unit    HTML     67K 
                Activity (Details)                                               
92: R77         Related Party Transactions (Details)                HTML     47K 
93: R78         INCOME TAXES - Loss before income taxes (Details)   HTML     44K 
94: R79         INCOME TAXES - Current and deferred income taxes    HTML     45K 
                (Details)                                                        
95: R80         INCOME TAXES - Reconciliation of Income Taxes       HTML     57K 
                (Details)                                                        
96: R81         INCOME TAXES - Deferred assets (Liabilities)        HTML     58K 
                (Details)                                                        
97: R82         INCOME TAXES - Net Operating Loss Carryforwards     HTML     41K 
                (Details)                                                        
98: R83         INCOME TAXES - Unrecognized tax benefits (Details)  HTML     35K 
99: R84         Other Benefits (Details)                            HTML     35K 
100: R85         Gain From Sale of Priority Review Voucher           HTML     40K  
                (Details)                                                        
101: R86         Subsequent Events (Details)                         HTML     39K  
104: XML         IDEA XML File -- Filing Summary                      XML    193K  
102: XML         XBRL Instance -- ymab-20221231x10k_htm               XML   1.92M  
103: EXCEL       IDEA Workbook of Financial Reports                  XLSX    181K  
12: EX-101.CAL  XBRL Calculations -- ymab-20221231_cal               XML    178K 
13: EX-101.DEF  XBRL Definitions -- ymab-20221231_def                XML    793K 
14: EX-101.LAB  XBRL Labels -- ymab-20221231_lab                     XML   1.51M 
15: EX-101.PRE  XBRL Presentations -- ymab-20221231_pre              XML   1.24M 
11: EX-101.SCH  XBRL Schema -- ymab-20221231                         XSD    244K 
105: JSON        XBRL Instance as JSON Data -- MetaLinks              469±   746K  
106: ZIP         XBRL Zipped Folder -- 0001558370-23-005073-xbrl      Zip    974K

‘EX-101.CAL’   —   XBRL Calculations — ymab-20221231_cal

This Exhibit is an XBRL XML File.

                                                                                                                                                                                
<?xml version="1.0" encoding="windows-1252"?>
<!-- XBRL document created with Toppan Merrill Bridge 10.2.0.4 -->
<!-- Based on XBRL 2.1 -->
<!-- Created on: 3/30/2023 7:21:07 PM -->
<!-- Modified on: 3/30/2023 7:21:07 PM -->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance">
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#StatementConsolidatedBalanceSheets" roleURI="http://www.ymabs.com/role/StatementConsolidatedBalanceSheets"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#StatementConsolidatedStatementsOfNetIncomeLossAndComprehensiveIncomeLoss" roleURI="http://www.ymabs.com/role/StatementConsolidatedStatementsOfNetIncomeLossAndComprehensiveIncomeLoss"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#StatementConsolidatedStatementsOfCashFlows" roleURI="http://www.ymabs.com/role/StatementConsolidatedStatementsOfCashFlows"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureProductRevenueDiscountsAndAllowancesDetails" roleURI="http://www.ymabs.com/role/DisclosureProductRevenueDiscountsAndAllowancesDetails"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureInventoriesDetails" roleURI="http://www.ymabs.com/role/DisclosureInventoriesDetails"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureInventoriesDetailsCalc2" roleURI="http://www.ymabs.com/role/DisclosureInventoriesDetailsCalc2"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureLicenseAgreementsAndCommitmentsLeaseMaturitiesDetailsCalc2" roleURI="http://www.ymabs.com/role/DisclosureLicenseAgreementsAndCommitmentsLeaseMaturitiesDetailsCalc2"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureAccruedLiabilitiesDetails" roleURI="http://www.ymabs.com/role/DisclosureAccruedLiabilitiesDetails"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureLicenseAgreementsAndCommitmentsLeaseMaturitiesDetails" roleURI="http://www.ymabs.com/role/DisclosureLicenseAgreementsAndCommitmentsLeaseMaturitiesDetails"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureRelatedPartyTransactionsDetails" roleURI="http://www.ymabs.com/role/DisclosureRelatedPartyTransactionsDetails"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureIncomeTaxesCurrentAndDeferredIncomeTaxesDetails" roleURI="http://www.ymabs.com/role/DisclosureIncomeTaxesCurrentAndDeferredIncomeTaxesDetails"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureIncomeTaxesReconciliationOfIncomeTaxesDetails" roleURI="http://www.ymabs.com/role/DisclosureIncomeTaxesReconciliationOfIncomeTaxesDetails"/>
<roleRef xlink:type="simple" xlink:href="ymab-20221231.xsd#DisclosureIncomeTaxesDeferredAssetsLiabilitiesDetails" roleURI="http://www.ymabs.com/role/DisclosureIncomeTaxesDeferredAssetsLiabilitiesDetails"/>
<calculationLink xlink:role="http://www.ymabs.com/role/StatementConsolidatedBalanceSheets" xlink:type="extended" xlink:title="00100 - Statement - Consolidated Balance Sheets">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Assets" xlink:label="us-gaap_Assets"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrent" xlink:label="us-gaap_AssetsCurrent_638158008640313795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Assets" xlink:to="us-gaap_AssetsCurrent_638158008640313795" order="1" use="optional" weight="1" priority="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_638158008640313795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AssetsCurrent_638158008640313795" xlink:to="us-gaap_CashAndCashEquivalentsAtCarryingValue_638158008640313795" order="1" use="optional" weight="1" priority="4"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="us-gaap_AccountsReceivableNetCurrent_638158008640313795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AssetsCurrent_638158008640313795" xlink:to="us-gaap_AccountsReceivableNetCurrent_638158008640313795" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNet" xlink:label="us-gaap_InventoryNet_638158008640313795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AssetsCurrent_638158008640313795" xlink:to="us-gaap_InventoryNet_638158008640313795" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssetsCurrent" xlink:label="us-gaap_OtherAssetsCurrent_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AssetsCurrent_638158008640313795" xlink:to="us-gaap_OtherAssetsCurrent_638158008640323794" order="4" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Assets" xlink:to="us-gaap_PropertyPlantAndEquipmentNet_638158008640323794" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="us-gaap_OperatingLeaseRightOfUseAsset_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Assets" xlink:to="us-gaap_OperatingLeaseRightOfUseAsset_638158008640323794" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="us-gaap_IntangibleAssetsNetExcludingGoodwill_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Assets" xlink:to="us-gaap_IntangibleAssetsNetExcludingGoodwill_638158008640323794" order="4" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="us-gaap_OtherAssetsNoncurrent_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Assets" xlink:to="us-gaap_OtherAssetsNoncurrent_638158008640323794" order="5" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities" xlink:label="us-gaap_Liabilities_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_Liabilities_638158008640323794" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrent" xlink:label="us-gaap_LiabilitiesCurrent_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_638158008640323794" xlink:to="us-gaap_LiabilitiesCurrent_638158008640323794" order="1" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsPayableCurrent" xlink:label="us-gaap_AccountsPayableCurrent_638158008640323794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LiabilitiesCurrent_638158008640323794" xlink:to="us-gaap_AccountsPayableCurrent_638158008640323794" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="us-gaap_AccruedLiabilitiesCurrent_638158008640333794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LiabilitiesCurrent_638158008640323794" xlink:to="us-gaap_AccruedLiabilitiesCurrent_638158008640333794" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="us-gaap_OperatingLeaseLiabilityCurrent_638158008640333794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LiabilitiesCurrent_638158008640323794" xlink:to="us-gaap_OperatingLeaseLiabilityCurrent_638158008640333794" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_AccruedMilestonePaymentsNoncurrent" xlink:label="ymab_AccruedMilestonePaymentsNoncurrent_638158008640333794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_638158008640323794" xlink:to="ymab_AccruedMilestonePaymentsNoncurrent_638158008640333794" order="2" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="us-gaap_OperatingLeaseLiabilityNoncurrent_638158008640333794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_638158008640323794" xlink:to="us-gaap_OperatingLeaseLiabilityNoncurrent_638158008640333794" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherLiabilitiesNoncurrent" xlink:label="us-gaap_OtherLiabilitiesNoncurrent_638158008640333794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_638158008640323794" xlink:to="us-gaap_OtherLiabilitiesNoncurrent_638158008640333794" order="4" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="us-gaap_CommitmentsAndContingencies_638158008640333794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_CommitmentsAndContingencies_638158008640333794" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity" xlink:label="us-gaap_StockholdersEquity_638158008640333794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_StockholdersEquity_638158008640333794" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockValue" xlink:label="us-gaap_PreferredStockValue_638158008640343818"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_638158008640333794" xlink:to="us-gaap_PreferredStockValue_638158008640343818" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockValue" xlink:label="us-gaap_CommonStockValue_638158008640343818"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_638158008640333794" xlink:to="us-gaap_CommonStockValue_638158008640343818" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="us-gaap_AdditionalPaidInCapital_638158008640343818"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_638158008640333794" xlink:to="us-gaap_AdditionalPaidInCapital_638158008640343818" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_638158008640343818"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_638158008640333794" xlink:to="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_638158008640343818" order="4" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_638158008640343818"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_638158008640333794" xlink:to="us-gaap_RetainedEarningsAccumulatedDeficit_638158008640343818" order="5" use="optional" weight="1" priority="2"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/StatementConsolidatedStatementsOfNetIncomeLossAndComprehensiveIncomeLoss" xlink:type="extended" xlink:title="00200 - Statement - Consolidated Statements of Net Income (Loss) and Comprehensive Income (Loss)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="us-gaap_ComprehensiveIncomeNetOfTax"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:label="us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ComprehensiveIncomeNetOfTax" xlink:to="us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_638158008640353795" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss" xlink:label="us-gaap_NetIncomeLoss_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ComprehensiveIncomeNetOfTax" xlink:to="us-gaap_NetIncomeLoss_638158008640353795" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainLossOnDispositionOfAssets1" xlink:label="us-gaap_GainLossOnDispositionOfAssets1_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLoss_638158008640353795" xlink:to="us-gaap_GainLossOnDispositionOfAssets1_638158008640353795" order="1" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="us-gaap_OtherNonoperatingIncomeExpense_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLoss_638158008640353795" xlink:to="us-gaap_OtherNonoperatingIncomeExpense_638158008640353795" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingIncomeLoss" xlink:label="us-gaap_OperatingIncomeLoss_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLoss_638158008640353795" xlink:to="us-gaap_OperatingIncomeLoss_638158008640353795" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingIncomeLoss_638158008640353795" xlink:to="us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_638158008640353795" order="1" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostsAndExpenses" xlink:label="us-gaap_CostsAndExpenses_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingIncomeLoss_638158008640353795" xlink:to="us-gaap_CostsAndExpenses_638158008640353795" order="2" use="optional" weight="-1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostOfGoodsAndServicesSold" xlink:label="us-gaap_CostOfGoodsAndServicesSold_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_638158008640353795" xlink:to="us-gaap_CostOfGoodsAndServicesSold_638158008640353795" order="1" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="us-gaap_ResearchAndDevelopmentExpense_638158008640353795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_638158008640353795" xlink:to="us-gaap_ResearchAndDevelopmentExpense_638158008640353795" order="2" use="optional" weight="1" priority="4"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_RoyaltyExpenseExcludingCostsIncludedInCostOfGoodsAndServicesSold" xlink:label="ymab_RoyaltyExpenseExcludingCostsIncludedInCostOfGoodsAndServicesSold_638158008640363802"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_638158008640353795" xlink:to="ymab_RoyaltyExpenseExcludingCostsIncludedInCostOfGoodsAndServicesSold_638158008640363802" order="3" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SellingGeneralAndAdministrativeExpense" xlink:label="us-gaap_SellingGeneralAndAdministrativeExpense_638158008640363802"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_638158008640353795" xlink:to="us-gaap_SellingGeneralAndAdministrativeExpense_638158008640363802" order="4" use="optional" weight="1" priority="2"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/StatementConsolidatedStatementsOfCashFlows" xlink:type="extended" xlink:title="00400 - Statement - Consolidated Statements of Cash Flows">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" order="1" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProfitLoss" xlink:label="us-gaap_ProfitLoss_638158008640363802"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_ProfitLoss_638158008640363802" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainLossOnDispositionOfAssets1" xlink:label="us-gaap_GainLossOnDispositionOfAssets1_638158008640363802"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_GainLossOnDispositionOfAssets1_638158008640363802" order="2" use="optional" weight="-1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="us-gaap_DepreciationDepletionAndAmortization_638158008640363802"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_DepreciationDepletionAndAmortization_638158008640363802" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensation" xlink:label="us-gaap_ShareBasedCompensation_638158008640363802"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_ShareBasedCompensation_638158008640363802" order="4" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims" xlink:label="us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims_638158008640373796" order="5" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ForeignCurrencyTransactionGainLossBeforeTaxAndOtherTransactions" xlink:label="ymab_ForeignCurrencyTransactionGainLossBeforeTaxAndOtherTransactions_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="ymab_ForeignCurrencyTransactionGainLossBeforeTaxAndOtherTransactions_638158008640373796" order="6" use="optional" weight="-1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="us-gaap_IncreaseDecreaseInAccountsReceivable_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_IncreaseDecreaseInAccountsReceivable_638158008640373796" order="7" use="optional" weight="-1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="us-gaap_IncreaseDecreaseInInventories_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_IncreaseDecreaseInInventories_638158008640373796" order="8" use="optional" weight="-1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherCurrentAssets" xlink:label="us-gaap_IncreaseDecreaseInOtherCurrentAssets_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_IncreaseDecreaseInOtherCurrentAssets_638158008640373796" order="9" use="optional" weight="-1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentAssets" xlink:label="us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_638158008640373796" order="10" use="optional" weight="-1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayable_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="us-gaap_IncreaseDecreaseInAccountsPayable_638158008640373796" order="11" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_IncreaseDecreaseInAccruedLiabilitiesAndOther" xlink:label="ymab_IncreaseDecreaseInAccruedLiabilitiesAndOther_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_638158008640363802" xlink:to="ymab_IncreaseDecreaseInAccruedLiabilitiesAndOther_638158008640373796" order="12" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInInvestingActivities_638158008640373796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:to="us-gaap_NetCashProvidedByUsedInInvestingActivities_638158008640373796" order="2" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_638158008640383799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivities_638158008640373796" xlink:to="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_638158008640383799" order="1" use="optional" weight="-1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireIntangibleAssets" xlink:label="us-gaap_PaymentsToAcquireIntangibleAssets_638158008640383799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivities_638158008640373796" xlink:to="us-gaap_PaymentsToAcquireIntangibleAssets_638158008640383799" order="2" use="optional" weight="-1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleOfProductiveAssets" xlink:label="us-gaap_ProceedsFromSaleOfProductiveAssets_638158008640383799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivities_638158008640373796" xlink:to="us-gaap_ProceedsFromSaleOfProductiveAssets_638158008640383799" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_638158008640383799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivities_638158008640383799" order="3" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="us-gaap_ProceedsFromIssuanceOfCommonStock_638158008640383799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_638158008640383799" xlink:to="us-gaap_ProceedsFromIssuanceOfCommonStock_638158008640383799" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="us-gaap_ProceedsFromStockOptionsExercised_638158008640393799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_638158008640383799" xlink:to="us-gaap_ProceedsFromStockOptionsExercised_638158008640393799" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations" xlink:label="us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_638158008640393799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:to="us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_638158008640393799" order="4" use="optional" weight="1"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureProductRevenueDiscountsAndAllowancesDetails" xlink:type="extended" xlink:title="40402 - Disclosure - PRODUCT REVENUE - Discounts and Allowances (Details)">
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ReservesAndAllowancesAdditions" xlink:label="ymab_ReservesAndAllowancesAdditions"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ReserveForDiscountsAdditions" xlink:label="ymab_ReserveForDiscountsAdditions_638158008640393799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesAdditions" xlink:to="ymab_ReserveForDiscountsAdditions_638158008640393799" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ContractualAllowanceAndGovernmentRebateLiabilityAdditions" xlink:label="ymab_ContractualAllowanceAndGovernmentRebateLiabilityAdditions_638158008640393799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesAdditions" xlink:to="ymab_ContractualAllowanceAndGovernmentRebateLiabilityAdditions_638158008640393799" order="2" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_SalesReturnLiabilityAdditions" xlink:label="ymab_SalesReturnLiabilityAdditions_638158008640393799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesAdditions" xlink:to="ymab_SalesReturnLiabilityAdditions_638158008640393799" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ReservesAndAllowancesBalance" xlink:label="ymab_ReservesAndAllowancesBalance"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ReserveForDiscountsBalance" xlink:label="ymab_ReserveForDiscountsBalance_638158008640393799"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesBalance" xlink:to="ymab_ReserveForDiscountsBalance_638158008640393799" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ContractualAllowanceAndGovernmentRebateLiabilityBalance" xlink:label="ymab_ContractualAllowanceAndGovernmentRebateLiabilityBalance_638158008640403797"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesBalance" xlink:to="ymab_ContractualAllowanceAndGovernmentRebateLiabilityBalance_638158008640403797" order="2" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_SalesReturnLiabilityBalance" xlink:label="ymab_SalesReturnLiabilityBalance_638158008640403797"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesBalance" xlink:to="ymab_SalesReturnLiabilityBalance_638158008640403797" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ReservesAndAllowancesReductions" xlink:label="ymab_ReservesAndAllowancesReductions"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ReserveForDiscountsReduction" xlink:label="ymab_ReserveForDiscountsReduction_638158008640403797"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesReductions" xlink:to="ymab_ReserveForDiscountsReduction_638158008640403797" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ContractualAllowanceAndGovernmentRebateLiabilityReduction" xlink:label="ymab_ContractualAllowanceAndGovernmentRebateLiabilityReduction_638158008640403797"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesReductions" xlink:to="ymab_ContractualAllowanceAndGovernmentRebateLiabilityReduction_638158008640403797" order="2" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_SalesReturnLiabilityReduction" xlink:label="ymab_SalesReturnLiabilityReduction_638158008640403797"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesAndAllowancesReductions" xlink:to="ymab_SalesReturnLiabilityReduction_638158008640403797" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ReservesForDiscountsAndAllowancesChangeInEstimate" xlink:label="ymab_ReservesForDiscountsAndAllowancesChangeInEstimate"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_ContractualAllowanceAndGovernmentRebateChangeInEstimate" xlink:label="ymab_ContractualAllowanceAndGovernmentRebateChangeInEstimate_638158008640403797"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_ReservesForDiscountsAndAllowancesChangeInEstimate" xlink:to="ymab_ContractualAllowanceAndGovernmentRebateChangeInEstimate_638158008640403797" order="1" use="optional" weight="1"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureInventoriesDetails" xlink:type="extended" xlink:title="40601 - Disclosure - INVENTORIES (Details)">
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_InventoryCurrentAndNoncurrent" xlink:label="ymab_InventoryCurrentAndNoncurrent"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNet" xlink:label="us-gaap_InventoryNet_638158008640403797"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_InventoryCurrentAndNoncurrent" xlink:to="us-gaap_InventoryNet_638158008640403797" order="1" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNoncurrent" xlink:label="us-gaap_InventoryNoncurrent_638158008640413794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_InventoryCurrentAndNoncurrent" xlink:to="us-gaap_InventoryNoncurrent_638158008640413794" order="2" use="optional" weight="1"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureInventoriesDetailsCalc2" xlink:type="extended" xlink:title="40601 - Disclosure - INVENTORIES (Details) Calc 2">
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_InventoryCurrentAndNoncurrent" xlink:label="ymab_InventoryCurrentAndNoncurrent_1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryWorkInProcessNetOfReserves" xlink:label="us-gaap_InventoryWorkInProcessNetOfReserves_638158008640413794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_InventoryCurrentAndNoncurrent_1" xlink:to="us-gaap_InventoryWorkInProcessNetOfReserves_638158008640413794" order="1" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:label="us-gaap_InventoryFinishedGoodsNetOfReserves_638158008640413794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_InventoryCurrentAndNoncurrent_1" xlink:to="us-gaap_InventoryFinishedGoodsNetOfReserves_638158008640413794" order="2" use="optional" weight="1"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureLicenseAgreementsAndCommitmentsLeaseMaturitiesDetailsCalc2" xlink:type="extended" xlink:title="40608 - Disclosure - LICENSE AGREEMENTS AND COMMITMENTS - Lease maturities (Details) (calc 2)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_638158008640413794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_638158008640413794" order="1" use="optional" weight="1" priority="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiability" xlink:label="us-gaap_OperatingLeaseLiability_638158008640413794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_OperatingLeaseLiability_638158008640413794" order="2" use="optional" weight="1" priority="2"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureAccruedLiabilitiesDetails" xlink:type="extended" xlink:title="40801 - Disclosure - ACCRUED LIABILITIES (Details)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="us-gaap_AccruedLiabilitiesCurrent"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_AccruedLicensingMilestoneAndRoyaltyPaymentsCurrent" xlink:label="ymab_AccruedLicensingMilestoneAndRoyaltyPaymentsCurrent_638158008640413794"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="ymab_AccruedLicensingMilestoneAndRoyaltyPaymentsCurrent_638158008640413794" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_AccruedClinicalCostsCurrent" xlink:label="ymab_AccruedClinicalCostsCurrent_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="ymab_AccruedClinicalCostsCurrent_638158008640423796" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_AccruedCompensationAndBoardFeesCurrent" xlink:label="ymab_AccruedCompensationAndBoardFeesCurrent_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="ymab_AccruedCompensationAndBoardFeesCurrent_638158008640423796" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_AccruedManufacturingCostsCurrent" xlink:label="ymab_AccruedManufacturingCostsCurrent_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="ymab_AccruedManufacturingCostsCurrent_638158008640423796" order="4" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_AccruedSalesReservesCurrent" xlink:label="ymab_AccruedSalesReservesCurrent_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="ymab_AccruedSalesReservesCurrent_638158008640423796" order="5" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="us-gaap_OtherAccruedLiabilitiesCurrent_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="us-gaap_OtherAccruedLiabilitiesCurrent_638158008640423796" order="6" use="optional" weight="1" priority="3"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureLicenseAgreementsAndCommitmentsLeaseMaturitiesDetails" xlink:type="extended" xlink:title="40909 - Disclosure - LICENSE AGREEMENTS AND COMMITMENTS - Lease maturities (Details)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_638158008640423796" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_638158008640423796" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_638158008640423796" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_638158008640423796"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_638158008640423796" order="4" use="optional" weight="1" priority="2"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureRelatedPartyTransactionsDetails" xlink:type="extended" xlink:title="41201 - Disclosure - RELATED PARTY TRANSACTIONS (Details)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DueToRelatedPartiesCurrent" xlink:label="us-gaap_DueToRelatedPartiesCurrent"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsPayableRelatedPartiesCurrent" xlink:label="us-gaap_AccountsPayableRelatedPartiesCurrent_638158008640433800"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DueToRelatedPartiesCurrent" xlink:to="us-gaap_AccountsPayableRelatedPartiesCurrent_638158008640433800" order="1" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_AccruedLiabilitiesRelatedPartiesCurrent" xlink:label="ymab_AccruedLiabilitiesRelatedPartiesCurrent_638158008640433800"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DueToRelatedPartiesCurrent" xlink:to="ymab_AccruedLiabilitiesRelatedPartiesCurrent_638158008640433800" order="2" use="optional" weight="1"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureIncomeTaxesCurrentAndDeferredIncomeTaxesDetails" xlink:type="extended" xlink:title="41302 - Disclosure - INCOME TAXES - Current and deferred income taxes (Details)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="us-gaap_IncomeTaxExpenseBenefit_1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:label="us-gaap_CurrentIncomeTaxExpenseBenefit_638158008640433800"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit_1" xlink:to="us-gaap_CurrentIncomeTaxExpenseBenefit_638158008640433800" order="1" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CurrentForeignTaxExpenseBenefit" xlink:label="us-gaap_CurrentForeignTaxExpenseBenefit_638158008640433800"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CurrentIncomeTaxExpenseBenefit_638158008640433800" xlink:to="us-gaap_CurrentForeignTaxExpenseBenefit_638158008640433800" order="1" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="us-gaap_DeferredIncomeTaxExpenseBenefit_638158008640433800"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit_1" xlink:to="us-gaap_DeferredIncomeTaxExpenseBenefit_638158008640433800" order="2" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredForeignIncomeTaxExpenseBenefit" xlink:label="us-gaap_DeferredForeignIncomeTaxExpenseBenefit_638158008640433800"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DeferredIncomeTaxExpenseBenefit_638158008640433800" xlink:to="us-gaap_DeferredForeignIncomeTaxExpenseBenefit_638158008640433800" order="1" use="optional" weight="1"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureIncomeTaxesReconciliationOfIncomeTaxesDetails" xlink:type="extended" xlink:title="41303 - Disclosure - INCOME TAXES - Reconciliation of Income Taxes (Details)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="us-gaap_IncomeTaxExpenseBenefit"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:label="us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_638158008640443795" order="1" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes" xlink:label="us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_638158008640443795" order="2" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate" xlink:label="us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_638158008640443795" order="3" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:label="us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_638158008640443795" order="4" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:label="us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_638158008640443795" order="5" use="optional" weight="1" priority="2"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxReconciliationTaxCredits" xlink:label="us-gaap_IncomeTaxReconciliationTaxCredits_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxReconciliationTaxCredits_638158008640443795" order="6" use="optional" weight="-1" priority="2"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_EffectiveIncomeTaxRateReconciliationUncertainTaxPositionAmount" xlink:label="ymab_EffectiveIncomeTaxRateReconciliationUncertainTaxPositionAmount_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="ymab_EffectiveIncomeTaxRateReconciliationUncertainTaxPositionAmount_638158008640443795" order="7" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_EffectiveIncomeTaxRateReconciliationDeferredAdjustmentsAmount" xlink:label="ymab_EffectiveIncomeTaxRateReconciliationDeferredAdjustmentsAmount_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="ymab_EffectiveIncomeTaxRateReconciliationDeferredAdjustmentsAmount_638158008640443795" order="8" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments" xlink:label="us-gaap_IncomeTaxReconciliationOtherAdjustments_638158008640443795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxReconciliationOtherAdjustments_638158008640443795" order="9" use="optional" weight="1" priority="2"/>
</calculationLink>
<calculationLink xlink:role="http://www.ymabs.com/role/DisclosureIncomeTaxesDeferredAssetsLiabilitiesDetails" xlink:type="extended" xlink:title="41304 - Disclosure - INCOME TAXES - Deferred assets (liabilities) (Details)">
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet" xlink:label="us-gaap_DeferredTaxAssetsLiabilitiesNet"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsValuationAllowance" xlink:label="us-gaap_DeferredTaxAssetsValuationAllowance_638158008640453795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DeferredTaxAssetsLiabilitiesNet" xlink:to="us-gaap_DeferredTaxAssetsValuationAllowance_638158008640453795" order="1" use="optional" weight="-1" priority="3"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_DeferredTaxAssetsNetOfLiabilitiesGross" xlink:label="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DeferredTaxAssetsLiabilitiesNet" xlink:to="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" order="2" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets" xlink:label="us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_638158008640453795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_638158008640453795" order="1" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses" xlink:label="us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses_638158008640453795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="us-gaap_DeferredTaxAssetsUnrealizedCurrencyLosses_638158008640453795" order="2" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_DeferredTaxAssetsAccruedRoyalty" xlink:label="ymab_DeferredTaxAssetsAccruedRoyalty_638158008640453795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="ymab_DeferredTaxAssetsAccruedRoyalty_638158008640453795" order="3" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_638158008640453795"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_638158008640453795" order="4" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_638158008640463812"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_638158008640463812" order="5" use="optional" weight="1" priority="4"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwards" xlink:label="us-gaap_DeferredTaxAssetsTaxCreditCarryforwards_638158008640463812"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="us-gaap_DeferredTaxAssetsTaxCreditCarryforwards_638158008640463812" order="6" use="optional" weight="1" priority="4"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_DeferredTaxAssetsCapitalizedResearchAndExperimentation" xlink:label="ymab_DeferredTaxAssetsCapitalizedResearchAndExperimentation_638158008640463812"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="ymab_DeferredTaxAssetsCapitalizedResearchAndExperimentation_638158008640463812" order="7" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_DeferredTaxLiabilitiesRightOfUseAsset" xlink:label="ymab_DeferredTaxLiabilitiesRightOfUseAsset_638158008640463812"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="ymab_DeferredTaxLiabilitiesRightOfUseAsset_638158008640463812" order="8" use="optional" weight="-1" priority="3"/>
<loc xlink:type="locator" xlink:href="ymab-20221231.xsd#ymab_DeferredTaxAssetLeaseLiability" xlink:label="ymab_DeferredTaxAssetLeaseLiability_638158008640463812"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="ymab_DeferredTaxAssetLeaseLiability_638158008640463812" order="9" use="optional" weight="1" priority="3"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxAssetsOther" xlink:label="us-gaap_DeferredTaxAssetsOther_638158008640463812"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="us-gaap_DeferredTaxAssetsOther_638158008640463812" order="10" use="optional" weight="1"/>
<loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredTaxLiabilitiesOther" xlink:label="us-gaap_DeferredTaxLiabilitiesOther_638158008640463812"/>
<calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="ymab_DeferredTaxAssetsNetOfLiabilitiesGross_638158008640453795" xlink:to="us-gaap_DeferredTaxLiabilitiesOther_638158008640463812" order="11" use="optional" weight="-1"/>
</calculationLink>
</link:linkbase>

4 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 2/29/24  Y-mAbs Therapeutics, Inc.         10-K       12/31/23  101:10M                                    Toppan Merrill Bridge/FA
 5/08/23  Y-mAbs Therapeutics, Inc.         10-Q        3/31/23   85:7.4M                                   Toppan Merrill Bridge/FA
 3/30/23  Y-mAbs Therapeutics, Inc.         S-8         3/30/23    4:168K                                   Toppan Merrill Bridge/FA
 3/30/23  Y-mAbs Therapeutics, Inc.         S-3                    5:975K                                   Toppan Merrill Bridge/FA

13 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

11/07/22  Y-mAbs Therapeutics, Inc.         10-Q        9/30/22   88:8.4M                                   Toppan Merrill Bridge/FA
 8/08/22  Y-mAbs Therapeutics, Inc.         10-Q        6/30/22   85:8M                                     Toppan Merrill Bridge/FA
 5/09/22  Y-mAbs Therapeutics, Inc.         10-Q        3/31/22   85:7.2M                                   Toppan Merrill Bridge/FA
 5/06/21  Y-mAbs Therapeutics, Inc.         10-Q        3/31/21   76:6.3M                                   Toppan Merrill Bridge/FA
 2/19/21  Y-mAbs Therapeutics, Inc.         8-K:7,8,9   2/17/21   15:2.7M                                   Toppan Merrill/FA
12/22/20  Y-mAbs Therapeutics, Inc.         8-K:1,9    12/17/20   11:674K                                   Toppan Merrill/FA
11/05/20  Y-mAbs Therapeutics, Inc.         10-Q        9/30/20   68:6.7M                                   Toppan Merrill Bridge/FA
10/08/20  Y-mAbs Therapeutics, Inc.         8-K:1,9    10/07/20   11:294K                                   Toppan Merrill/FA
 4/21/20  Y-mAbs Therapeutics, Inc.         8-K:1,9     4/15/20    2:348K                                   Toppan Merrill/FA
12/19/19  Y-mAbs Therapeutics, Inc.         8-K:1,9    12/13/19    3:170K                                   Toppan Merrill/FA
 9/19/19  Y-mAbs Therapeutics, Inc.         8-K:1,9     9/13/19    2:129K                                   Toppan Merrill/FA
 9/07/18  Y-mAbs Therapeutics, Inc.         S-1/A                  5:4.4M                                   Toppan Merrill-FA
 8/24/18  Y-mAbs Therapeutics, Inc.         S-1                   31:12M                                    Toppan Merrill-FA
↑Top
Filing Submission 0001558370-23-005073   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)
Copyright © 2024 Fran Finnegan & Company LLC – All Rights Reserved.
About — Privacy — Redactions — Help — Fri., May 10, 7:42:08.2am ET