SEC Info - Bank of N.T. Butterfield & Son Ltd. - ‘20-F’ for 12/31/20

SEC Info℠

Home

Help

Please Sign In

Bank of N.T. Butterfield & Son Ltd. – ‘20-F’ for 12/31/20 – ‘EX-101.PRE’

On: Tuesday, 2/23/21, at 4:32pm ET · For: 12/31/20 · Accession #: 1653242-21-8 · File #: 1-37877

  As Of               Filer                 Filing    For·On·As Docs:Size

 2/23/21  Bank of NT Butterfield & Son Ltd  20-F       12/31/20  155:33M

Annual or Annual-Transition Report by a Foreign Non-Canadian Issuer — Form 20-F — SEA’34
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 20-F        20-F 2020 the Bank of N.T. Butterfield and Son      HTML   4.08M 
                Limited                                                          
 2: EX-2.2      EX-2.2 Description of Securities                    HTML     84K 
 3: EX-8        EX-8 List of Subsidiaries                           HTML     48K 
 6: EX-13.1     EX-13.1 CEO Attestation                             HTML     42K 
 4: EX-12.1     EX-12.1 CEO Certification                           HTML     44K 
 5: EX-12.2     EX-12.2 CFO Certification                           HTML     44K 
 7: EX-15.1     EX-15.1 Consent of Pricewaterhousecoopers Ltd       HTML     39K 
14: R1          Cover Page                                          HTML    112K 
15: R2          Consolidated Balance Sheets                         HTML    146K 
16: R3          Consolidated Balance Sheets (Parenthetical)         HTML     56K 
17: R4          Consolidated Statements of Operations               HTML    159K 
18: R5          Consolidated Statements of Comprehensive Income     HTML     68K 
19: R6          Consolidated Statements of Changes in               HTML    110K 
                Shareholders' Equity                                             
20: R7          Consolidated Statements of Changes in               HTML     43K 
                Shareholders' Equity (Parenthetical)                             
21: R8          Consolidated Statements of Cash Flows               HTML    167K 
22: R9          Nature of business                                  HTML     43K 
23: R10         Significant accounting policies                     HTML    147K 
24: R11         Cash due from banks                                 HTML     51K 
25: R12         Short-term investments                              HTML     54K 
26: R13         Investment in securities                            HTML    202K 
27: R14         Loans                                               HTML    393K 
28: R15         Credit risk concentrations                          HTML    114K 
29: R16         Premises, equipment and computer software           HTML     68K 
30: R17         Goodwill and other intangible assets                HTML     75K 
31: R18         Customer deposits and deposits from banks           HTML     98K 
32: R19         Employee benefit plans                              HTML    242K 
33: R20         Credit-related arrangements, repurchase agreements  HTML     77K 
                and commitments                                                  
34: R21         Leases                                              HTML     98K 
35: R22         Loan interest income                                HTML     53K 
36: R23         Segmented information                               HTML    149K 
37: R24         Derivative instruments and risk management          HTML    121K 
38: R25         Fair value measurements                             HTML    231K 
39: R26         Interest rate risk                                  HTML    231K 
40: R27         Long-term debt                                      HTML     62K 
41: R28         Earnings per share                                  HTML     61K 
42: R29         Share-based payments                                HTML    146K 
43: R30         Share buy-back plans                                HTML     52K 
44: R31         Accumulated other comprehensive loss                HTML    124K 
45: R32         Capital structure                                   HTML     67K 
46: R33         Income taxes                                        HTML     82K 
47: R34         Business combinations                               HTML     72K 
48: R35         Related party transactions                          HTML     80K 
49: R36         Condensed financial statements of the parent        HTML    219K 
                company only                                                     
50: R37         Subsequent events                                   HTML     41K 
51: R38         Significant accounting policies (Policies)          HTML    215K 
52: R39         Cash due from banks (Tables)                        HTML     50K 
53: R40         Short-term investments (Tables)                     HTML     53K 
54: R41         Investment in securities (Tables)                   HTML    198K 
55: R42         Loans (Tables)                                      HTML    394K 
56: R43         Credit risk concentrations (Tables)                 HTML    114K 
57: R44         Premises, equipment and computer software (Tables)  HTML     67K 
58: R45         Goodwill and other intangible assets (Tables)       HTML     76K 
59: R46         Customer deposits and deposits from banks (Tables)  HTML     98K 
60: R47         Employee benefit plans (Tables)                     HTML    241K 
61: R48         Credit-related arrangements, repurchase agreements  HTML     74K 
                and commitments (Tables)                                         
62: R49         Leases (Tables)                                     HTML     69K 
63: R50         Loan interest income (Tables)                       HTML     53K 
64: R51         Segmented information (Tables)                      HTML    139K 
65: R52         Derivative instruments and risk management          HTML    140K 
                (Tables)                                                         
66: R53         Fair value measurements (Tables)                    HTML    130K 
67: R54         Interest rate risk (Tables)                         HTML    147K 
68: R55         Long-term debt (Tables)                             HTML     59K 
69: R56         Earnings per share (Tables)                         HTML     59K 
70: R57         Share-based payments (Tables)                       HTML    143K 
71: R58         Share buy-back plans (Tables)                       HTML     50K 
72: R59         Accumulated other comprehensive loss (Tables)       HTML    125K 
73: R60         Capital structure (Tables)                          HTML     64K 
74: R61         Income taxes (Tables)                               HTML     82K 
75: R62         Business combinations (Tables)                      HTML     68K 
76: R63         Related party transactions (Tables)                 HTML     76K 
77: R64         Condensed financial statements of the parent        HTML    221K 
                company only (Tables)                                            
78: R65         Nature of business (Details)                        HTML     41K 
79: R66         Significant accounting policies (Details)           HTML     73K 
80: R67         Cash due from banks (Details)                       HTML     54K 
81: R68         Short-term investments (Details)                    HTML     56K 
82: R69         Investment in securities - Amortized Cost,          HTML     93K 
                Carrying Amount and Fair Value (Details)                         
83: R70         Investment in securities - Narrative (Details)      HTML     57K 
84: R71         Investment in securities - Continuous Unrealized    HTML     89K 
                Loss Position (Details)                                          
85: R72         Investment in securities - Investment Maturities    HTML     94K 
                (Details)                                                        
86: R73         Investment in securities - Pledged Investments      HTML     48K 
                (Details)                                                        
87: R74         Investment in securities - Sale Proceeds and        HTML     62K 
                Realized Gains and Losses of AFS Securities                      
                (Details)                                                        
88: R75         Loans - Additional Information (Details)            HTML     43K 
89: R76         Loans - Loans' Credit Quality (Details)             HTML    214K 
90: R77         Loans - Age Analysis of Past Due Loans (Including   HTML    135K 
                Non-Accrual Loans) (Details)                                     
91: R78         Loans - Changes in Allowances for Credit Losses     HTML     85K 
                (Details)                                                        
92: R79         Loans - Non-Performing Loans (Details)              HTML    109K 
93: R80         Loans - Loans Modified in a TDR (Details)           HTML     64K 
94: R81         Credit risk concentrations (Details)                HTML    153K 
95: R82         Premises, equipment and computer software -         HTML     66K 
                Schedule of Premise, Equipment, and Computer                     
                Software (Details)                                               
96: R83         Goodwill and other intangible assets - Goodwill     HTML     56K 
                (Details)                                                        
97: R84         Goodwill and other intangible assets - Customer     HTML     58K 
                Relationship Intangible Assets (Details)                         
98: R85         Goodwill and other intangible assets - Narrative    HTML     70K 
                (Details)                                                        
99: R86         Customer deposits and deposits from banks           HTML     87K 
                (Details)                                                        
100: R87         Customer deposits and deposits from banks - By      HTML     53K  
                Type and Segment (Details)                                       
101: R88         Employee benefit plans - Narrative (Details)        HTML     58K  
102: R89         Employee benefit plans - Financial Position of      HTML    111K  
                Defined Benefit Plans (Details)                                  
103: R90         Employee benefit plans - Amounts Recognized in      HTML    125K  
                AOCI, Benefit Expense (Income), and OCI (Details)                
104: R91         Employee benefit plans - Actuarial Assumptions      HTML     67K  
                (Details)                                                        
105: R92         Employee benefit plans - Investments Policies and   HTML     52K  
                Strategies (Details)                                             
106: R93         Employee benefit plans - Fair Value Measurements    HTML     93K  
                of Pension Plans' Assets (Details)                               
107: R94         Employee benefit plans - Estimated Future           HTML     61K  
                Contributions (Details)                                          
108: R95         Credit-related arrangements, repurchase agreements  HTML     57K  
                and commitments - Commitments (Details)                          
109: R96         Credit-related arrangements, repurchase agreements  HTML     77K  
                and commitments - Contractual Obligation, Fiscal                 
                Year Maturity Schedule (Details)                                 
110: R97         Credit-related arrangements, repurchase agreements  HTML     56K  
                and commitments - Credit-Related Arrangements                    
                (Details)                                                        
111: R98         Credit-related arrangements, repurchase agreements  HTML     49K  
                and commitments - Repurchase Agreements (Details)                
112: R99         Credit-related arrangements, repurchase agreements  HTML     45K  
                and commitments - Legal Proceedings (Details)                    
113: R100        Leases - Narrative (Details)                        HTML     40K  
114: R101        Leases - Summary of Lease Costs and Lessee          HTML     89K  
                Operating Lease Liability Maturity (Details)                     
115: R102        Loan interest income (Details)                      HTML     57K  
116: R103        Segmented information (Details)                     HTML    125K  
117: R104        Derivative instruments and risk management -        HTML     82K  
                Schedule of Notional Amounts and Related Fair                    
                Value Measurements of Derivative Instruments                     
                (Details)                                                        
118: R105        Derivative instruments and risk management -        HTML     76K  
                Offsetting (Details)                                             
119: R106        Derivative instruments and risk management -        HTML     63K  
                Location and Amount of Gains (Losses) (Details)                  
120: R107        Fair value measurements - Financial Assets and      HTML     98K  
                Liabilities Measured at Fair Value (Details)                     
121: R108        Fair value measurements - Level 3 Reconciliation    HTML     48K  
                (Details)                                                        
122: R109        Fair value measurements - Items Other Than Those    HTML     81K  
                Recognized at Fair Value on a Recurring Basis                    
                (Details)                                                        
123: R110        Interest rate risk (Details)                        HTML    116K  
124: R111        Long-term debt - Additional Information (Details)   HTML     95K  
125: R112        Long-term debt - Contractual Maturity (Details)     HTML     71K  
126: R113        Earnings per share (Details)                        HTML     87K  
127: R114        Share-based payments - Additional Information       HTML    127K  
                (Details)                                                        
128: R115        Share-based payments - Changes in Outstanding       HTML     88K  
                Stock Options (Details)                                          
129: R116        Share-based payments - Changes in Outstanding       HTML     68K  
                ELTIP and EDIP Awards (Details)                                  
130: R117        Share-based payments - Share-based Compensation     HTML     44K  
                Cost Recognized in Net Income (Details) (Details)                
131: R118        Share-based payments - Unrecognized Share-based     HTML     55K  
                Compensation Cost (Details)                                      
132: R119        Share buy-back plans (Details)                      HTML     65K  
133: R120        Accumulated other comprehensive loss - Schedule of  HTML     71K  
                AOCL Components (Details)                                        
134: R121        Accumulated other comprehensive loss - Net Change   HTML    105K  
                of AOCL Components (Details)                                     
135: R122        Capital structure - Authorized Capital (Details)    HTML     73K  
136: R123        Capital structure - Dividends (Details)             HTML     48K  
137: R124        Capital structure - Regulatory Capital (Details)    HTML     70K  
138: R125        Income taxes - Income Taxes in Consolidated         HTML     49K  
                Statements of Operations (Details)                               
139: R126        Income taxes - Reconciliation between the           HTML     72K  
                Effective Income Tax Rate and the Statutory Income               
                Tax Rate (Details)                                               
140: R127        Income taxes - Deferred Income Taxes (Details)      HTML     60K  
141: R128        Income taxes - Narrative (Details)                  HTML     49K  
142: R129        Business combinations - Deutsche Bank?s Global      HTML     62K  
                Trust Solutions (Details)                                        
143: R130        Business combinations - Total Consideration         HTML     79K  
                Transferred (Details)                                            
144: R131        Business combinations - ABN AMRO (Channel Islands)  HTML     59K  
                Limited Acquisition (Details)                                    
145: R132        Business combinations - Pro Forma Information       HTML     46K  
                (Details)                                                        
146: R133        Related party transactions - Financing              HTML     64K  
                Transactions (Details)                                           
147: R134        Related party transactions - Financial              HTML     60K  
                Transactions With Related Parties (Details)                      
148: R135        Condensed financial statements of the parent        HTML    135K  
                company only - Condensed Balance Sheets (Details)                
149: R136        Condensed financial statements of the parent        HTML    162K  
                company only - Condensed Statements of Operations                
                (Details)                                                        
150: R137        Condensed financial statements of the parent        HTML    198K  
                company only - Condensed Statements of Cash Flows                
                (Details)                                                        
151: R138        Subsequent events (Details)                         HTML     51K  
153: XML         IDEA XML File -- Filing Summary                      XML    299K  
13: XML         XBRL Instance -- ntb-20201231_htm                    XML   9.86M 
152: EXCEL       IDEA Workbook of Financial Reports                  XLSX    265K  
 9: EX-101.CAL  XBRL Calculations -- ntb-20201231_cal                XML    697K 
10: EX-101.DEF  XBRL Definitions -- ntb-20201231_def                 XML   1.92M 
11: EX-101.LAB  XBRL Labels -- ntb-20201231_lab                      XML   3.76M 
12: EX-101.PRE  XBRL Presentations -- ntb-20201231_pre               XML   2.52M 
 8: EX-101.SCH  XBRL Schema -- ntb-20201231                          XSD    359K 
154: JSON        XBRL Instance as JSON Data -- MetaLinks              838±  1.30M  
155: ZIP         XBRL Zipped Folder -- 0001653242-21-000008-xbrl      Zip   1.69M

‘EX-101.PRE’ — XBRL Presentations — ntb-20201231_pre

This Exhibit is an XBRL XML File.

<?xml version="1.0" encoding="windows-1252"?>

<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CoverPage" xlink:type="simple" xlink:href="ntb-20201231.xsd#CoverPage"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CoverPage" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_6f3f77b6-e0a8-444f-a404-2d7805132144" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CoverAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityListingsTable_6693db5d-f9d3-4588-aaba-f679a166375d" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityListingsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6f3f77b6-e0a8-444f-a404-2d7805132144" xlink:to="loc_dei_EntityListingsTable_6693db5d-f9d3-4588-aaba-f679a166375d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressesAddressTypeAxis_4904b88d-bfa7-4e9a-898f-869088c3f7d4" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressesAddressTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsTable_6693db5d-f9d3-4588-aaba-f679a166375d" xlink:to="loc_dei_EntityAddressesAddressTypeAxis_4904b88d-bfa7-4e9a-898f-869088c3f7d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_AddressTypeDomain_3f574598-a07b-4ee0-8a12-78be6d8b23f6" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AddressTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityAddressesAddressTypeAxis_4904b88d-bfa7-4e9a-898f-869088c3f7d4" xlink:to="loc_dei_AddressTypeDomain_3f574598-a07b-4ee0-8a12-78be6d8b23f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_BusinessContactMember_e7c450b7-75cd-45f7-aef6-e5af26d17512" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_BusinessContactMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_AddressTypeDomain_3f574598-a07b-4ee0-8a12-78be6d8b23f6" xlink:to="loc_dei_BusinessContactMember_e7c450b7-75cd-45f7-aef6-e5af26d17512" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityListingsExchangeAxis_93fe6a61-b6eb-4eb1-8294-d277ec952fde" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityListingsExchangeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsTable_6693db5d-f9d3-4588-aaba-f679a166375d" xlink:to="loc_dei_EntityListingsExchangeAxis_93fe6a61-b6eb-4eb1-8294-d277ec952fde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_ExchangeDomain_ab6782db-6bed-4b0a-aead-c0bbedbf66b5" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_ExchangeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsExchangeAxis_93fe6a61-b6eb-4eb1-8294-d277ec952fde" xlink:to="loc_dei_ExchangeDomain_ab6782db-6bed-4b0a-aead-c0bbedbf66b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NewYorkStockExchangeMember_7294ac89-85ea-4b10-8883-005d332f2815" xlink:href="ntb-20201231.xsd#ntb_NewYorkStockExchangeMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_ExchangeDomain_ab6782db-6bed-4b0a-aead-c0bbedbf66b5" xlink:to="loc_ntb_NewYorkStockExchangeMember_7294ac89-85ea-4b10-8883-005d332f2815" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BermudaStockExchangeMember_d909cb3e-703b-4faf-ba4f-95effb935371" xlink:href="ntb-20201231.xsd#ntb_BermudaStockExchangeMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_ExchangeDomain_ab6782db-6bed-4b0a-aead-c0bbedbf66b5" xlink:to="loc_ntb_BermudaStockExchangeMember_d909cb3e-703b-4faf-ba4f-95effb935371" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityListingsLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsTable_6693db5d-f9d3-4588-aaba-f679a166375d" xlink:to="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_d375390f-4d39-432f-bf55-2dc92e631156" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentType_d375390f-4d39-432f-bf55-2dc92e631156" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentRegistrationStatement_0fc4c1b6-b4e5-4a70-a4ff-5b502d07702a" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentRegistrationStatement"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentRegistrationStatement_0fc4c1b6-b4e5-4a70-a4ff-5b502d07702a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentAnnualReport_742aaca5-7beb-466c-bddd-cbe175679452" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentAnnualReport"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentAnnualReport_742aaca5-7beb-466c-bddd-cbe175679452" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_daf7aae6-0493-48e1-9054-766d031794c5" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentPeriodEndDate_daf7aae6-0493-48e1-9054-766d031794c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_bdef5d2d-7675-4090-a6c1-343c0464ffcc" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CurrentFiscalYearEndDate"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_CurrentFiscalYearEndDate_bdef5d2d-7675-4090-a6c1-343c0464ffcc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_d8804c45-4708-4b8a-8f90-842b8a07aac6" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentTransitionReport"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentTransitionReport_d8804c45-4708-4b8a-8f90-842b8a07aac6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentShellCompanyReport_a66046c1-9922-4be7-9c66-f8f697abbbff" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentShellCompanyReport"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentShellCompanyReport_a66046c1-9922-4be7-9c66-f8f697abbbff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_0e162578-184f-4302-aca9-5a123b2211b5" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityFileNumber_0e162578-184f-4302-aca9-5a123b2211b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_ece645ce-ad72-404f-a397-922bf5cb39f7" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityIncorporationStateCountryCode_ece645ce-ad72-404f-a397-922bf5cb39f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_085dc190-1801-40c8-947a-df89c931b3bd" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityAddressAddressLine1_085dc190-1801-40c8-947a-df89c931b3bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_35a69caf-573e-4331-b11c-8d6e4959729d" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityAddressCityOrTown_35a69caf-573e-4331-b11c-8d6e4959729d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_0abfd531-215d-4ec5-aba7-cbab5841d244" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityAddressPostalZipCode_0abfd531-215d-4ec5-aba7-cbab5841d244" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCountry_b405fc14-a6a9-47b5-a172-f6305e9deeb1" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCountry"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityAddressCountry_b405fc14-a6a9-47b5-a172-f6305e9deeb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_ContactPersonnelName_fbac09d8-cc73-4c38-ab60-d58883bf0d8b" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_ContactPersonnelName"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_ContactPersonnelName_fbac09d8-cc73-4c38-ab60-d58883bf0d8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_d7b21483-a96e-4dfe-8212-8daefec12a9d" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_CityAreaCode_d7b21483-a96e-4dfe-8212-8daefec12a9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_5ca9a41e-796f-471a-aab4-fb0876b889c5" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber"/>

<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_LocalPhoneNumber_5ca9a41e-796f-471a-aab4-fb0876b889c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_ContactPersonnelFaxNumber_cff1b40c-eee8-42ac-ae1c-558efc473441" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_ContactPersonnelFaxNumber"/>

<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_ContactPersonnelFaxNumber_cff1b40c-eee8-42ac-ae1c-558efc473441" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_ContactPersonnelEmailAddress_b36bd060-4fde-4ab5-85fa-44aa6b3cc985" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_ContactPersonnelEmailAddress"/>

<link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_ContactPersonnelEmailAddress_b36bd060-4fde-4ab5-85fa-44aa6b3cc985" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_eba47763-04f1-43b6-8725-6fd4c15e49d6" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle"/>

<link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_Security12bTitle_eba47763-04f1-43b6-8725-6fd4c15e49d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_83a01037-6a67-4407-8a8a-74ee60fab583" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol"/>

<link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_TradingSymbol_83a01037-6a67-4407-8a8a-74ee60fab583" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_d197e2c7-bb38-47b6-b3a8-dcaa3b6bf3c1" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SecurityExchangeName"/>

<link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_SecurityExchangeName_d197e2c7-bb38-47b6-b3a8-dcaa3b6bf3c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_Security12gTitle_968b92f1-58a7-41b9-a078-2fe9ab8f7fb5" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12gTitle"/>

<link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_Security12gTitle_968b92f1-58a7-41b9-a078-2fe9ab8f7fb5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_bb94b0a6-5e2a-466f-a4ab-51b1ce6c8485" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCommonStockSharesOutstanding"/>

<link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_bb94b0a6-5e2a-466f-a4ab-51b1ce6c8485" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityWellKnownSeasonedIssuer_20e92388-64cf-4055-a9f5-2f8e3e9f624b" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityWellKnownSeasonedIssuer"/>

<link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityWellKnownSeasonedIssuer_20e92388-64cf-4055-a9f5-2f8e3e9f624b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityVoluntaryFilers_3e27333d-6075-4bc3-a0c3-4c4957a1d784" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityVoluntaryFilers"/>

<link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityVoluntaryFilers_3e27333d-6075-4bc3-a0c3-4c4957a1d784" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_a7d56bbd-05cb-4d19-ad31-b69b723c5143" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCurrentReportingStatus"/>

<link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityCurrentReportingStatus_a7d56bbd-05cb-4d19-ad31-b69b723c5143" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_e7ca1039-bc3a-4900-807e-d2b8bee376fd" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityInteractiveDataCurrent"/>

<link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityInteractiveDataCurrent_e7ca1039-bc3a-4900-807e-d2b8bee376fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_dd986e3a-4f73-49e6-95c0-364b62b1c7e8" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFilerCategory"/>

<link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityFilerCategory_dd986e3a-4f73-49e6-95c0-364b62b1c7e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_1df69d08-a5f6-4904-861c-1c822176998b" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany"/>

<link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityEmergingGrowthCompany_1df69d08-a5f6-4904-861c-1c822176998b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_IcfrAuditorAttestationFlag_dd4acd8d-9207-44ca-b07d-bdb14d7215e2" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_IcfrAuditorAttestationFlag"/>

<link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_IcfrAuditorAttestationFlag_dd4acd8d-9207-44ca-b07d-bdb14d7215e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentAccountingStandard_eb2ccd4f-e8df-4989-89f3-5ff7e8607df2" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentAccountingStandard"/>

<link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentAccountingStandard_eb2ccd4f-e8df-4989-89f3-5ff7e8607df2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_40a00ef8-3171-4985-b956-5c69e93c463f" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityShellCompany"/>

<link:presentationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityShellCompany_40a00ef8-3171-4985-b956-5c69e93c463f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_ae9f8e3c-d977-496c-ae50-5a26454e58eb" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag"/>

<link:presentationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_AmendmentFlag_ae9f8e3c-d977-496c-ae50-5a26454e58eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_7cd64306-bf79-4bab-b456-6ea4e5c7e3e2" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName"/>

<link:presentationArc order="34" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityRegistrantName_7cd64306-bf79-4bab-b456-6ea4e5c7e3e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_93f188f0-72b3-4dc1-b0b9-499cd8d6cf98" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey"/>

<link:presentationArc order="35" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_EntityCentralIndexKey_93f188f0-72b3-4dc1-b0b9-499cd8d6cf98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_fd23ba7d-98bc-4a2e-8c5d-d866b10f72ad" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentFiscalYearFocus"/>

<link:presentationArc order="36" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentFiscalYearFocus_fd23ba7d-98bc-4a2e-8c5d-d866b10f72ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_81605907-413d-4993-97e2-c33f4fff6669" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentFiscalPeriodFocus"/>

<link:presentationArc order="37" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityListingsLineItems_660033f3-0678-49f5-990c-af596a94ac59" xlink:to="loc_dei_DocumentFiscalPeriodFocus_81605907-413d-4993-97e2-c33f4fff6669" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ConsolidatedBalanceSheets" xlink:type="simple" xlink:href="ntb-20201231.xsd#ConsolidatedBalanceSheets"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ConsolidatedBalanceSheets" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_1fdc6fe8-cbd2-4464-96bc-343a57375ba2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_1fdc6fe8-cbd2-4464-96bc-343a57375ba2" xlink:to="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndDueFromBanks_7331a78d-6890-49ba-996f-af5a3b0d8b25" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndDueFromBanks"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_CashAndDueFromBanks_7331a78d-6890-49ba-996f-af5a3b0d8b25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositsInBanks_0e015be4-aa8d-4f18-9a87-4534c8eee87c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestBearingDepositsInBanks"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_InterestBearingDepositsInBanks_0e015be4-aa8d-4f18-9a87-4534c8eee87c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashEquivalentsAtCarryingValue_ec4c8f0b-5ce2-4033-8f93-02402adc3d8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashEquivalentsAtCarryingValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_CashEquivalentsAtCarryingValue_ec4c8f0b-5ce2-4033-8f93-02402adc3d8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_8f40b17e-8703-4608-b9d8-456c9d785a74" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_8f40b17e-8703-4608-b9d8-456c9d785a74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuritiesPurchasedUnderAgreementsToResell_adbd7441-cc50-44fc-9c85-ee148b8995ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SecuritiesPurchasedUnderAgreementsToResell"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_SecuritiesPurchasedUnderAgreementsToResell_adbd7441-cc50-44fc-9c85-ee148b8995ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherShortTermInvestments_bbceb0e6-c00f-4036-ac00-54a4f04b5914" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherShortTermInvestments"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_OtherShortTermInvestments_bbceb0e6-c00f-4036-ac00-54a4f04b5914" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecuritiesAbstract_e36cb1ec-7ed7-405a-aa67-d2e0e175ca38" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketableSecuritiesAbstract"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_MarketableSecuritiesAbstract_e36cb1ec-7ed7-405a-aa67-d2e0e175ca38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_cd4896a7-c344-4049-96ce-d03fa4436a1c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_e36cb1ec-7ed7-405a-aa67-d2e0e175ca38" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_cd4896a7-c344-4049-96ce-d03fa4436a1c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1e8d0324-2714-4d79-888f-80f474ae057b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_e36cb1ec-7ed7-405a-aa67-d2e0e175ca38" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1e8d0324-2714-4d79-888f-80f474ae057b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecurities_73c2ba00-3a89-41d4-abd7-93eb96157694" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecurities"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_e36cb1ec-7ed7-405a-aa67-d2e0e175ca38" xlink:to="loc_us-gaap_HeldToMaturitySecurities_73c2ba00-3a89-41d4-abd7-93eb96157694" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecurities_8fc6c238-e533-4071-84b1-f76eb050c36e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketableSecurities"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_e36cb1ec-7ed7-405a-aa67-d2e0e175ca38" xlink:to="loc_us-gaap_MarketableSecurities_8fc6c238-e533-4071-84b1-f76eb050c36e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableNetAbstract_5aaff823-62b3-4440-9a54-0db7f7308526" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableNetAbstract"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_NotesReceivableNetAbstract_5aaff823-62b3-4440-9a54-0db7f7308526" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross_154978bc-afac-4dbe-bba7-b74e92810511" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableGross"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NotesReceivableNetAbstract_5aaff823-62b3-4440-9a54-0db7f7308526" xlink:to="loc_us-gaap_NotesReceivableGross_154978bc-afac-4dbe-bba7-b74e92810511" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_2c433123-acb2-4360-b4e4-e2b1844ffc04" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLosses"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NotesReceivableNetAbstract_5aaff823-62b3-4440-9a54-0db7f7308526" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_2c433123-acb2-4360-b4e4-e2b1844ffc04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableNet_87deea05-5bda-4da1-8b08-fcccaac12673" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableNet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NotesReceivableNetAbstract_5aaff823-62b3-4440-9a54-0db7f7308526" xlink:to="loc_us-gaap_NotesReceivableNet_87deea05-5bda-4da1-8b08-fcccaac12673" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_87322c76-806f-4dbc-bc56-bb0705e68af8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_87322c76-806f-4dbc-bc56-bb0705e68af8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_4afb45e0-8da1-4499-9f87-5a2eb4b8bc87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_Goodwill_4afb45e0-8da1-4499-9f87-5a2eb4b8bc87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIntangibleAssetsNet_e2fa5aab-042c-4276-9514-4c3acd6d0a60" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherIntangibleAssetsNet"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_OtherIntangibleAssetsNet_e2fa5aab-042c-4276-9514-4c3acd6d0a60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsInAffiliatesSubsidiariesAssociatesAndJointVentures_233fffb7-7544-4c5d-b4ca-89ca08178df4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsInAffiliatesSubsidiariesAssociatesAndJointVentures"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_InvestmentsInAffiliatesSubsidiariesAssociatesAndJointVentures_233fffb7-7544-4c5d-b4ca-89ca08178df4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherRealEstate_b70933f3-5247-430b-a34b-8b74df777e99" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherRealEstate"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_OtherRealEstate_b70933f3-5247-430b-a34b-8b74df777e99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssets_fa4855ea-e9b7-459e-9644-086ae5535c05" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssets"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_OtherAssets_fa4855ea-e9b7-459e-9644-086ae5535c05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_54e35b29-80a5-4144-8561-a7b63bbe4ad6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_160f78f5-db32-439a-93b1-954ba3cb7e71" xlink:to="loc_us-gaap_Assets_54e35b29-80a5-4144-8561-a7b63bbe4ad6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAbstract_95ac185a-2e59-4777-9943-aa0104cfec95" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_1fdc6fe8-cbd2-4464-96bc-343a57375ba2" xlink:to="loc_us-gaap_LiabilitiesAbstract_95ac185a-2e59-4777-9943-aa0104cfec95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_95ac185a-2e59-4777-9943-aa0104cfec95" xlink:to="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestBearingDepositLiabilities_9b312a79-6005-4f49-8365-fab7aa9019c7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestBearingDepositLiabilities"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_us-gaap_NoninterestBearingDepositLiabilities_9b312a79-6005-4f49-8365-fab7aa9019c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositLiabilities_4cf01574-7930-4b27-8a06-aaeaacde06ad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestBearingDepositLiabilities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_us-gaap_InterestBearingDepositLiabilities_4cf01574-7930-4b27-8a06-aaeaacde06ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Deposits_e846cbce-11a6-40d5-a430-c7cf2104394f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Deposits"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_us-gaap_Deposits_e846cbce-11a6-40d5-a430-c7cf2104394f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent_82630c33-43d2-4868-bc84-35c9d5604e03" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent_82630c33-43d2-4868-bc84-35c9d5604e03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherLiabilitiesMiscellaneous_ce881bb8-36aa-45f5-8a7d-d5c0dca196d3" xlink:href="ntb-20201231.xsd#ntb_OtherLiabilitiesMiscellaneous"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_ntb_OtherLiabilitiesMiscellaneous_ce881bb8-36aa-45f5-8a7d-d5c0dca196d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilities_b473ad26-6f62-4974-9e6a-eff44b4d5ddf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherLiabilities"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_us-gaap_OtherLiabilities_b473ad26-6f62-4974-9e6a-eff44b4d5ddf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_01ba0889-7fe7-402f-8ba2-26e0df897b8e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebt"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_us-gaap_LongTermDebt_01ba0889-7fe7-402f-8ba2-26e0df897b8e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_e5fca751-3bad-4ea8-9ee0-6ade034c17d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Liabilities"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsInterestBearingAndNoninterestBearingAlternativeAbstract_bae9a337-94b1-4385-8f7f-5999e921fc96" xlink:to="loc_us-gaap_Liabilities_e5fca751-3bad-4ea8-9ee0-6ade034c17d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_2a4968ce-7642-470c-b5b2-edd4c56c3747" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_1fdc6fe8-cbd2-4464-96bc-343a57375ba2" xlink:to="loc_us-gaap_CommitmentsAndContingencies_2a4968ce-7642-470c-b5b2-edd4c56c3747" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_1fdc6fe8-cbd2-4464-96bc-343a57375ba2" xlink:to="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_adc1a724-1c5b-4f5a-a7a5-b108a5f4b46c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockValue"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:to="loc_us-gaap_CommonStockValue_adc1a724-1c5b-4f5a-a7a5-b108a5f4b46c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_c5bbd5bb-10cf-44a6-a7b4-3727a677ca72" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapital"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:to="loc_us-gaap_AdditionalPaidInCapital_c5bbd5bb-10cf-44a6-a7b4-3727a677ca72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_5956ac05-0be2-45f6-964c-8904de23192c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_5956ac05-0be2-45f6-964c-8904de23192c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonValue_a79695a0-bd0a-446b-a7ef-708b1cdd34a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockCommonValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:to="loc_us-gaap_TreasuryStockCommonValue_a79695a0-bd0a-446b-a7ef-708b1cdd34a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_28e8a95a-772b-4ce8-a898-a6a0be4c94d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_28e8a95a-772b-4ce8-a898-a6a0be4c94d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_5931c882-eb8b-40b0-999b-33839a7ae589" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_500c3354-4cbb-4a42-b7b3-2db914ae6bcf" xlink:to="loc_us-gaap_StockholdersEquity_5931c882-eb8b-40b0-999b-33839a7ae589" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_2255cbb3-bc84-45e6-9591-358ba131d9dd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_1fdc6fe8-cbd2-4464-96bc-343a57375ba2" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_2255cbb3-bc84-45e6-9591-358ba131d9dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="ntb-20201231.xsd#ConsolidatedBalanceSheetsParenthetical"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_da15672e-c121-4c24-934a-64149f80dc28" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_37ac4a53-e019-4cdf-91ec-4936c9e10ef3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_da15672e-c121-4c24-934a-64149f80dc28" xlink:to="loc_us-gaap_StatementTable_37ac4a53-e019-4cdf-91ec-4936c9e10ef3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_7b0dc545-2b77-4185-b4aa-7953c45b94ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_37ac4a53-e019-4cdf-91ec-4936c9e10ef3" xlink:to="loc_us-gaap_StatementClassOfStockAxis_7b0dc545-2b77-4185-b4aa-7953c45b94ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_e2d966d3-7f38-4555-8c3d-fbf12dfa2634" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_7b0dc545-2b77-4185-b4aa-7953c45b94ca" xlink:to="loc_us-gaap_ClassOfStockDomain_e2d966d3-7f38-4555-8c3d-fbf12dfa2634" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonClassAMember_709d58ba-4b42-4776-91d2-07743d4b5d6b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonClassAMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_e2d966d3-7f38-4555-8c3d-fbf12dfa2634" xlink:to="loc_us-gaap_CommonClassAMember_709d58ba-4b42-4776-91d2-07743d4b5d6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonvotingCommonStockMember_5904f501-d3ce-4007-8b38-050df3b66f70" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NonvotingCommonStockMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_e2d966d3-7f38-4555-8c3d-fbf12dfa2634" xlink:to="loc_us-gaap_NonvotingCommonStockMember_5904f501-d3ce-4007-8b38-050df3b66f70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_37ac4a53-e019-4cdf-91ec-4936c9e10ef3" xlink:to="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_25b2c497-5901-4c19-912e-cc1d8c5f4c60" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_25b2c497-5901-4c19-912e-cc1d8c5f4c60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_0c265859-e0bc-4344-bc0b-af7727abb07d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesFairValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesFairValue_0c265859-e0bc-4344-bc0b-af7727abb07d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_0c6f262e-083a-496c-b877-3ae71feb9bc2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_0c6f262e-083a-496c-b877-3ae71feb9bc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_521429d2-236d-4df9-aa14-a71c73fbf3e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_521429d2-236d-4df9-aa14-a71c73fbf3e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_40833adb-086c-4b18-bb54-bfbe6d5e59a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesIssued"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:to="loc_us-gaap_CommonStockSharesIssued_40833adb-086c-4b18-bb54-bfbe6d5e59a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_53fdfb4e-7dcd-4f53-a572-56a28d7e303b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_53fdfb4e-7dcd-4f53-a572-56a28d7e303b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonShares_09f6a99d-14d3-4ff1-b6e8-0880e341aad7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockCommonShares"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_684e2417-5511-4a0a-ba70-395c307f32af" xlink:to="loc_us-gaap_TreasuryStockCommonShares_09f6a99d-14d3-4ff1-b6e8-0880e341aad7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofOperations" xlink:type="simple" xlink:href="ntb-20201231.xsd#ConsolidatedStatementsofOperations"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofOperations" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:href="ntb-20201231.xsd#ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BrokerageCommissionsRevenue_7c31284a-a057-400d-8825-aae60896feb7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BrokerageCommissionsRevenue"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:to="loc_us-gaap_BrokerageCommissionsRevenue_7c31284a-a057-400d-8825-aae60896feb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentBankingRevenue_24764093-72c4-402b-82e6-606129ba508e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentBankingRevenue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:to="loc_us-gaap_InvestmentBankingRevenue_24764093-72c4-402b-82e6-606129ba508e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_71322a21-c41c-4d88-8228-df06b9ab6175" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_71322a21-c41c-4d88-8228-df06b9ab6175" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TrustIncome_ce511271-1240-455a-9ef9-62e404963229" xlink:href="ntb-20201231.xsd#ntb_TrustIncome"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:to="loc_ntb_TrustIncome_ce511271-1240-455a-9ef9-62e404963229" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CustodyandOtherAdministrationServicesRevenue_6ed4235d-7f8b-4a77-9c14-b504111d495a" xlink:href="ntb-20201231.xsd#ntb_CustodyandOtherAdministrationServicesRevenue"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:to="loc_ntb_CustodyandOtherAdministrationServicesRevenue_6ed4235d-7f8b-4a77-9c14-b504111d495a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestIncomeOther_e236d0ec-fc60-443d-bf23-34b446a1aa4d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestIncomeOther"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:to="loc_us-gaap_NoninterestIncomeOther_e236d0ec-fc60-443d-bf23-34b446a1aa4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther_00b9345f-4bf7-4ed7-8889-30ab97e8b7c3" xlink:href="ntb-20201231.xsd#ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_0797c370-c497-4269-b04a-1eace2b442c9" xlink:to="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther_00b9345f-4bf7-4ed7-8889-30ab97e8b7c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_5089cbe8-e98c-4912-92ff-33d47558a532" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndDividendIncomeOperatingAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_5089cbe8-e98c-4912-92ff-33d47558a532" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_331fec49-69df-42c8-a4ab-eae354c81cb0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndFeeIncomeLoansAndLeases"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_5089cbe8-e98c-4912-92ff-33d47558a532" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_331fec49-69df-42c8-a4ab-eae354c81cb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeSecuritiesByClassificationAbstract_e98131c3-abf4-4696-a3e7-010177ecb962" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndDividendIncomeSecuritiesByClassificationAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_5089cbe8-e98c-4912-92ff-33d47558a532" xlink:to="loc_us-gaap_InterestAndDividendIncomeSecuritiesByClassificationAbstract_e98131c3-abf4-4696-a3e7-010177ecb962" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeDebtSecuritiesAvailableForSaleOperating_4036fc34-6d0b-4eec-960e-bc3538455e1f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeDebtSecuritiesAvailableForSaleOperating"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeSecuritiesByClassificationAbstract_e98131c3-abf4-4696-a3e7-010177ecb962" xlink:to="loc_us-gaap_InterestIncomeDebtSecuritiesAvailableForSaleOperating_4036fc34-6d0b-4eec-960e-bc3538455e1f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeSecuritiesHeldToMaturity_5ca1ee2b-b4bd-4587-96c3-362854311fd2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndDividendIncomeSecuritiesHeldToMaturity"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeSecuritiesByClassificationAbstract_e98131c3-abf4-4696-a3e7-010177ecb962" xlink:to="loc_us-gaap_InterestAndDividendIncomeSecuritiesHeldToMaturity_5ca1ee2b-b4bd-4587-96c3-362854311fd2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeDepositsWithFinancialInstitutions_a09cfd55-06a8-49e3-8344-5ccacd9dcc02" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeDepositsWithFinancialInstitutions"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_5089cbe8-e98c-4912-92ff-33d47558a532" xlink:to="loc_us-gaap_InterestIncomeDepositsWithFinancialInstitutions_a09cfd55-06a8-49e3-8344-5ccacd9dcc02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating_288314c6-418a-4deb-816f-3361c54fe1d5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndDividendIncomeOperating"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_5089cbe8-e98c-4912-92ff-33d47558a532" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperating_288314c6-418a-4deb-816f-3361c54fe1d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseAbstract_1d775602-bc19-470b-8783-9e2a42e1353e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_InterestExpenseAbstract_1d775602-bc19-470b-8783-9e2a42e1353e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDeposits_cad0f308-2221-4352-8911-855df3d738cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseDeposits"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_1d775602-bc19-470b-8783-9e2a42e1353e" xlink:to="loc_us-gaap_InterestExpenseDeposits_cad0f308-2221-4352-8911-855df3d738cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseLongTermDebt_010ffb5e-a0c7-40ba-a4a5-94eb6c32701d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseLongTermDebt"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_1d775602-bc19-470b-8783-9e2a42e1353e" xlink:to="loc_us-gaap_InterestExpenseLongTermDebt_010ffb5e-a0c7-40ba-a4a5-94eb6c32701d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase_663aeed5-d5a0-4990-a37b-d45bef97c8d8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_1d775602-bc19-470b-8783-9e2a42e1353e" xlink:to="loc_us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase_663aeed5-d5a0-4990-a37b-d45bef97c8d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_5a22a6e5-7529-498a-957d-5a656424d6e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpense"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_1d775602-bc19-470b-8783-9e2a42e1353e" xlink:to="loc_us-gaap_InterestExpense_5a22a6e5-7529-498a-957d-5a656424d6e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_259adb23-306a-405b-843b-b0fcc5af9af3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseNet"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_259adb23-306a-405b-843b-b0fcc5af9af3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLossesExpensed_6f042862-d985-40a2-9979-bb8f75a05e8d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForLoanLossesExpensed"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_ProvisionForLoanLossesExpensed_6f042862-d985-40a2-9979-bb8f75a05e8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_04965861-4eb4-42b4-9e44-dffa547241b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_04965861-4eb4-42b4-9e44-dffa547241b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiRealizedGainLoss_cf80c3c1-c212-43be-95ec-e1fc3c0891b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNiRealizedGainLoss"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_EquitySecuritiesFvNiRealizedGainLoss_cf80c3c1-c212-43be-95ec-e1fc3c0891b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_63e68e58-e5ee-40eb-a417-8f30423eb9ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_63e68e58-e5ee-40eb-a417-8f30423eb9ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_d1ad163a-a66a-42e3-ae36-8df24224db78" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnSalesOfOtherRealEstate"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_d1ad163a-a66a-42e3-ae36-8df24224db78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NoninterestIncomeOtherOperatingIncomeExpense_18d75d33-06e6-4403-a1fc-d4249fb70dc1" xlink:href="ntb-20201231.xsd#ntb_NoninterestIncomeOtherOperatingIncomeExpense"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_ntb_NoninterestIncomeOtherOperatingIncomeExpense_18d75d33-06e6-4403-a1fc-d4249fb70dc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss_5012265d-1a3c-4bcf-a2b8-3e107be8106e" xlink:href="ntb-20201231.xsd#ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss_5012265d-1a3c-4bcf-a2b8-3e107be8106e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_7a3f6ee6-f8eb-4388-a54c-bcb4c2458a6d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Revenues"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_Revenues_7a3f6ee6-f8eb-4388-a54c-bcb4c2458a6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestExpenseAbstract"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LaborAndRelatedExpense_be33a16b-a009-47f9-ba6c-f0588492d6ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LaborAndRelatedExpense"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_LaborAndRelatedExpense_be33a16b-a009-47f9-ba6c-f0588492d6ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommunicationsAndInformationTechnology_eab263dd-8a13-46f8-ab13-f77f596eea2b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommunicationsAndInformationTechnology"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_CommunicationsAndInformationTechnology_eab263dd-8a13-46f8-ab13-f77f596eea2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProfessionalFees_513ce434-6609-4e60-8ec1-2e41de9e6868" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProfessionalFees"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_ProfessionalFees_513ce434-6609-4e60-8ec1-2e41de9e6868" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OccupancyNet_d1dc4986-b761-4fe7-9dea-7701077b920c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OccupancyNet"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_OccupancyNet_d1dc4986-b761-4fe7-9dea-7701077b920c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxesExcludingIncomeAndExciseTaxes_420b4ad9-16fa-4a84-ab61-91fef2216d8d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxesExcludingIncomeAndExciseTaxes"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_TaxesExcludingIncomeAndExciseTaxes_420b4ad9-16fa-4a84-ab61-91fef2216d8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponent_d7007154-07d8-4dd6-a9ca-e681478c83b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponent"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponent_d7007154-07d8-4dd6-a9ca-e681478c83b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingExpense_9b3d094d-2d8b-41d0-a2a0-8979c33617d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketingExpense"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_MarketingExpense_9b3d094d-2d8b-41d0-a2a0-8979c33617d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_7a4447ed-3656-4ca4-aae0-a57837c6afee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_7a4447ed-3656-4ca4-aae0-a57837c6afee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoninterestExpense_d96cdf6d-1cc6-4934-83ec-438723b2700a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNoninterestExpense"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_OtherNoninterestExpense_d96cdf6d-1cc6-4934-83ec-438723b2700a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpense_bb48af2d-cb8d-42cf-8697-53373cab4665" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestExpense"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_19b673ee-d878-4dd4-a294-76903899b51c" xlink:to="loc_us-gaap_NoninterestExpense_bb48af2d-cb8d-42cf-8697-53373cab4665" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_eca5828b-c998-42da-882c-9c291efa31fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_eca5828b-c998-42da-882c-9c291efa31fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_14e13184-1e5c-4514-a15f-f9d335abd03c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_14e13184-1e5c-4514-a15f-f9d335abd03c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_f8f3f3c8-8d25-4d3c-bb46-54283986d872" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_NetIncomeLoss_f8f3f3c8-8d25-4d3c-bb46-54283986d872" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_1ada5523-8dcb-4321-b295-fe1c57d536e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>

<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_7eadba09-9825-4775-8d9b-663f9d092cd8" xlink:to="loc_us-gaap_EarningsPerShareAbstract_1ada5523-8dcb-4321-b295-fe1c57d536e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_10e34430-786e-464c-aaac-5d982ccc6947" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasic"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_1ada5523-8dcb-4321-b295-fe1c57d536e9" xlink:to="loc_us-gaap_EarningsPerShareBasic_10e34430-786e-464c-aaac-5d982ccc6947" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_7c3ba43a-f4b8-4cb7-85f3-f142e49cd134" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_1ada5523-8dcb-4321-b295-fe1c57d536e9" xlink:to="loc_us-gaap_EarningsPerShareDiluted_7c3ba43a-f4b8-4cb7-85f3-f142e49cd134" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofComprehensiveIncome" xlink:type="simple" xlink:href="ntb-20201231.xsd#ConsolidatedStatementsofComprehensiveIncome"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofComprehensiveIncome" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_668f36b2-a678-428e-9557-dc789f9b6421" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_42e088a9-cbc1-4b88-a842-85058bec37e6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_668f36b2-a678-428e-9557-dc789f9b6421" xlink:to="loc_us-gaap_NetIncomeLoss_42e088a9-cbc1-4b88-a842-85058bec37e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_c53e4c34-faf6-4bc3-b4d0-cefd61c0616a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_668f36b2-a678-428e-9557-dc789f9b6421" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_c53e4c34-faf6-4bc3-b4d0-cefd61c0616a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_0e0b8c1c-cda5-4113-be33-c549260b2d06" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_c53e4c34-faf6-4bc3-b4d0-cefd61c0616a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_0e0b8c1c-cda5-4113-be33-c549260b2d06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTransfersFromHeldToMaturityToAvailableForSaleSecuritiesNetOfTax_b5bd3408-722f-4797-8245-09c87ae0df50" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTransfersFromHeldToMaturityToAvailableForSaleSecuritiesNetOfTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_c53e4c34-faf6-4bc3-b4d0-cefd61c0616a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTransfersFromHeldToMaturityToAvailableForSaleSecuritiesNetOfTax_b5bd3408-722f-4797-8245-09c87ae0df50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_947c4c87-3382-43b2-979d-ef06eb9a8dec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_c53e4c34-faf6-4bc3-b4d0-cefd61c0616a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_947c4c87-3382-43b2-979d-ef06eb9a8dec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_3969190e-334b-4e43-bbb1-57bcc523d5a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_c53e4c34-faf6-4bc3-b4d0-cefd61c0616a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_3969190e-334b-4e43-bbb1-57bcc523d5a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_d1b7a5ec-f780-4291-aac0-ac456ea22fe1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_c53e4c34-faf6-4bc3-b4d0-cefd61c0616a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_d1b7a5ec-f780-4291-aac0-ac456ea22fe1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_8e1db76a-ed1a-4d7b-a5c3-cb3105934679" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_668f36b2-a678-428e-9557-dc789f9b6421" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_8e1db76a-ed1a-4d7b-a5c3-cb3105934679" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofChangesinShareholdersEquity" xlink:type="simple" xlink:href="ntb-20201231.xsd#ConsolidatedStatementsofChangesinShareholdersEquity"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofChangesinShareholdersEquity" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_952e0f93-a449-4bbe-b150-1af76c0f149d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_f1cf6feb-e177-414f-a640-7313e93bd4da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_952e0f93-a449-4bbe-b150-1af76c0f149d" xlink:to="loc_us-gaap_StatementTable_f1cf6feb-e177-414f-a640-7313e93bd4da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_76c88169-cc89-493d-a21e-c4b0b9338050" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_f1cf6feb-e177-414f-a640-7313e93bd4da" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_76c88169-cc89-493d-a21e-c4b0b9338050" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_4f3af030-3e9b-48f4-9a9e-21a1deffd96b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_76c88169-cc89-493d-a21e-c4b0b9338050" xlink:to="loc_us-gaap_EquityComponentDomain_4f3af030-3e9b-48f4-9a9e-21a1deffd96b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_aa376b04-863d-48b6-af01-d2c0d1671df6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_4f3af030-3e9b-48f4-9a9e-21a1deffd96b" xlink:to="loc_us-gaap_CommonStockMember_aa376b04-863d-48b6-af01-d2c0d1671df6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_301f01a6-1d5e-464f-be69-3a34983cb1ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_4f3af030-3e9b-48f4-9a9e-21a1deffd96b" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_301f01a6-1d5e-464f-be69-3a34983cb1ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_9e41193f-49d8-484a-b229-7b89d60c2315" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_4f3af030-3e9b-48f4-9a9e-21a1deffd96b" xlink:to="loc_us-gaap_RetainedEarningsMember_9e41193f-49d8-484a-b229-7b89d60c2315" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonMember_fea591ca-c17b-4706-a9a2-5a3f74682aea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockCommonMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_4f3af030-3e9b-48f4-9a9e-21a1deffd96b" xlink:to="loc_us-gaap_TreasuryStockCommonMember_fea591ca-c17b-4706-a9a2-5a3f74682aea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_39c28c8c-5869-41aa-a283-c46c852fc717" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_4f3af030-3e9b-48f4-9a9e-21a1deffd96b" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_39c28c8c-5869-41aa-a283-c46c852fc717" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_2f351b0e-97eb-466d-97de-740bdc3abd16" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_f1cf6feb-e177-414f-a640-7313e93bd4da" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_2f351b0e-97eb-466d-97de-740bdc3abd16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_064b2ad1-4acf-4ec5-9b45-c2611d2581b7" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_2f351b0e-97eb-466d-97de-740bdc3abd16" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_064b2ad1-4acf-4ec5-9b45-c2611d2581b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_4d7bd039-e732-4729-855a-611fc75a09c5" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_064b2ad1-4acf-4ec5-9b45-c2611d2581b7" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_4d7bd039-e732-4729-855a-611fc75a09c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_837e8449-5de7-4c4d-9080-a256b83f505b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_f1cf6feb-e177-414f-a640-7313e93bd4da" xlink:to="loc_us-gaap_StatementLineItems_837e8449-5de7-4c4d-9080-a256b83f505b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_837e8449-5de7-4c4d-9080-a256b83f505b" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_f400d55f-8ede-4bbf-b378-952e9b6ff24f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharesOutstanding"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_SharesOutstanding_f400d55f-8ede-4bbf-b378-952e9b6ff24f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_5050463a-2ea7-4bb4-9e1f-e1e09d449466" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_StockholdersEquity_5050463a-2ea7-4bb4-9e1f-e1e09d449466" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingStandardsUpdateExtensibleList_0448e4b8-4d83-438d-8591-c4a6c1a0ff44" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingStandardsUpdateExtensibleList"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_AccountingStandardsUpdateExtensibleList_0448e4b8-4d83-438d-8591-c4a6c1a0ff44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_978ad449-23bf-4781-999c-84dbd1310c40" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodShares"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_978ad449-23bf-4781-999c-84dbd1310c40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_2b042dc8-720f-4be3-93e5-9ae92baace26" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodValue"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_2b042dc8-720f-4be3-93e5-9ae92baace26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_4f6c85e8-0784-4494-a3df-46b40a1be2ba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_4f6c85e8-0784-4494-a3df-46b40a1be2ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_a8fbf1e7-195a-45e4-b296-5bc63b90ef6c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_a8fbf1e7-195a-45e4-b296-5bc63b90ef6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_c65a37dd-ced2-4ee6-8f0e-b34c6291bbb7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_c65a37dd-ced2-4ee6-8f0e-b34c6291bbb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AdjustmentstoAdditionalPaidinCapitalShareBasedSettlements_e2bb1f6d-7960-4b7d-aaf5-c41613e59cf6" xlink:href="ntb-20201231.xsd#ntb_AdjustmentstoAdditionalPaidinCapitalShareBasedSettlements"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_ntb_AdjustmentstoAdditionalPaidinCapitalShareBasedSettlements_e2bb1f6d-7960-4b7d-aaf5-c41613e59cf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_183d145e-cec4-4e4b-82fa-971ab765c741" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_NetIncomeLoss_183d145e-cec4-4e4b-82fa-971ab765c741" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsCommonStockCash_ab3af579-7b58-4ce8-beb8-362e001cd864" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DividendsCommonStockCash"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_DividendsCommonStockCash_ab3af579-7b58-4ce8-beb8-362e001cd864" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_9f742c1c-2d7c-4a13-9471-c1bf74af9b21" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockSharesAcquired"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_9f742c1c-2d7c-4a13-9471-c1bf74af9b21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_80f8eac2-2d5c-46b6-b521-dacbf8c7db1d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_80f8eac2-2d5c-46b6-b521-dacbf8c7db1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_756231ff-2c48-4879-8e08-d5b0e97c3a2f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_756231ff-2c48-4879-8e08-d5b0e97c3a2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_c7053ecc-41e3-466f-bc04-2ad7ac33f707" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharesOutstanding"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_SharesOutstanding_c7053ecc-41e3-466f-bc04-2ad7ac33f707" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_5bf13f9c-3082-45bd-8c3e-00137a4ae246" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>

<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_c2ef367a-1a3d-42a8-9b8a-5b1eb79047e9" xlink:to="loc_us-gaap_StockholdersEquity_5bf13f9c-3082-45bd-8c3e-00137a4ae246" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofChangesinShareholdersEquityParenthetical" xlink:type="simple" xlink:href="ntb-20201231.xsd#ConsolidatedStatementsofChangesinShareholdersEquityParenthetical"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofChangesinShareholdersEquityParenthetical" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_13e94cd7-cdcb-462b-8f54-5bab10556bac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_95af2143-7ab1-4948-9b27-039bc6ffa782" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_13e94cd7-cdcb-462b-8f54-5bab10556bac" xlink:to="loc_us-gaap_StatementTable_95af2143-7ab1-4948-9b27-039bc6ffa782" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_caf6bb6c-46f5-4ad5-ac76-199bcbc0d501" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_95af2143-7ab1-4948-9b27-039bc6ffa782" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_caf6bb6c-46f5-4ad5-ac76-199bcbc0d501" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_a11a3fa8-d3b9-4bf6-82c6-2cdd1ac8dae7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_caf6bb6c-46f5-4ad5-ac76-199bcbc0d501" xlink:to="loc_us-gaap_EquityComponentDomain_a11a3fa8-d3b9-4bf6-82c6-2cdd1ac8dae7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_e3ee5638-a933-492f-aa2c-7024f44e0dbb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_a11a3fa8-d3b9-4bf6-82c6-2cdd1ac8dae7" xlink:to="loc_us-gaap_RetainedEarningsMember_e3ee5638-a933-492f-aa2c-7024f44e0dbb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_b2f8739a-8c35-49f0-8c44-6b0de41331be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_95af2143-7ab1-4948-9b27-039bc6ffa782" xlink:to="loc_us-gaap_StatementLineItems_b2f8739a-8c35-49f0-8c44-6b0de41331be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareDeclared_4a8c933f-d737-48c4-be96-412635e0d4e6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockDividendsPerShareDeclared"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b2f8739a-8c35-49f0-8c44-6b0de41331be" xlink:to="loc_us-gaap_CommonStockDividendsPerShareDeclared_4a8c933f-d737-48c4-be96-412635e0d4e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareCashPaid_08092092-8340-4a92-a527-83083f3c3fd1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockDividendsPerShareCashPaid"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_b2f8739a-8c35-49f0-8c44-6b0de41331be" xlink:to="loc_us-gaap_CommonStockDividendsPerShareCashPaid_08092092-8340-4a92-a527-83083f3c3fd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="ntb-20201231.xsd#ConsolidatedStatementsofCashFlows"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ConsolidatedStatementsofCashFlows" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_8e178b9d-5e3a-46c0-ac0d-2eec1d3a13ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_8e178b9d-5e3a-46c0-ac0d-2eec1d3a13ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_20fad8d6-3a91-4bd1-b17c-ad28a677d524" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_8e178b9d-5e3a-46c0-ac0d-2eec1d3a13ec" xlink:to="loc_us-gaap_NetIncomeLoss_20fad8d6-3a91-4bd1-b17c-ad28a677d524" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_8e178b9d-5e3a-46c0-ac0d-2eec1d3a13ec" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationAmortizationAndAccretionNet_9052c2ec-7326-49ad-9455-1e476e9b1fc9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationAmortizationAndAccretionNet"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_DepreciationAmortizationAndAccretionNet_9052c2ec-7326-49ad-9455-1e476e9b1fc9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLossesExpensed_30be04bf-ab24-40cf-96c6-b579044d29f4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForLoanLossesExpensed"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_ProvisionForLoanLossesExpensed_30be04bf-ab24-40cf-96c6-b579044d29f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_e112cfe8-03ae-4b73-98b3-43c18eed4e61" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensation"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_ShareBasedCompensation_e112cfe8-03ae-4b73-98b3-43c18eed4e61" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfTradingSecuritiesHeldforinvestment_c69bc2b9-2eda-495b-aecd-4c8e67c317f5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfTradingSecuritiesHeldforinvestment"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_ProceedsFromSaleOfTradingSecuritiesHeldforinvestment_c69bc2b9-2eda-495b-aecd-4c8e67c317f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PaymentsToAcquireDebtAndEquitySecuritiesFVNIHeldforinvestment_faf713ea-091b-401a-a133-1ce5166a23ec" xlink:href="ntb-20201231.xsd#ntb_PaymentsToAcquireDebtAndEquitySecuritiesFVNIHeldforinvestment"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_ntb_PaymentsToAcquireDebtAndEquitySecuritiesFVNIHeldforinvestment_faf713ea-091b-401a-a133-1ce5166a23ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_65be1c51-7779-42ea-b012-90e298cedae2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_65be1c51-7779-42ea-b012-90e298cedae2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_6127af11-41ff-498d-8952-8352cb2569f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnSalesOfOtherRealEstate"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_6127af11-41ff-498d-8952-8352cb2569f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_b06abdaf-c997-40d6-a8ec-1899fbaa14bf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_b06abdaf-c997-40d6-a8ec-1899fbaa14bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_05446d82-9dc8-4dde-b782-e5aa8527a4a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityMethodInvestmentDividendsOrDistributions"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_05446d82-9dc8-4dde-b782-e5aa8527a4a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_f98925da-d553-49a6-8745-f164f5e9472b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_321be07f-3b4d-41a9-8875-d507601d0b00" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_f98925da-d553-49a6-8745-f164f5e9472b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_dd12ff21-9c29-4826-bbcc-edfc1ed8079e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_f98925da-d553-49a6-8745-f164f5e9472b" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_dd12ff21-9c29-4826-bbcc-edfc1ed8079e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_99c0117e-7f9d-4d27-84fa-817495edbe0f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_f98925da-d553-49a6-8745-f164f5e9472b" xlink:to="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_99c0117e-7f9d-4d27-84fa-817495edbe0f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_69f52b61-a1be-40b2-94e4-42ed51994d9d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_8e178b9d-5e3a-46c0-ac0d-2eec1d3a13ec" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_69f52b61-a1be-40b2-94e4-42ed51994d9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForSecuritiesPurchasedUnderAgreementsToResell_c48a57f1-e8d3-4680-a751-c92f644431c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromPaymentsForSecuritiesPurchasedUnderAgreementsToResell"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_ProceedsFromPaymentsForSecuritiesPurchasedUnderAgreementsToResell_c48a57f1-e8d3-4680-a751-c92f644431c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments_1b9be994-cb99-4bfb-b77e-3178e8a7f587" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments_1b9be994-cb99-4bfb-b77e-3178e8a7f587" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireShortTermInvestments_1b90c984-0cdb-491f-8475-e2f41169df03" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireShortTermInvestments"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_PaymentsToAcquireShortTermInvestments_1b90c984-0cdb-491f-8475-e2f41169df03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_7e9819ab-0f29-4c7c-bac9-24c81f273572" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_7e9819ab-0f29-4c7c-bac9-24c81f273572" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_d53df400-27e3-4627-afd1-95b9b49bfea2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_d53df400-27e3-4627-afd1-95b9b49bfea2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_7af65b80-3625-4220-bc38-a0dd7c6366df" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_7af65b80-3625-4220-bc38-a0dd7c6366df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_a4e213ae-6fe8-43eb-bd15-dc162dfea67c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_a4e213ae-6fe8-43eb-bd15-dc162dfea67c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_03ecb7ab-57d1-433c-8db2-72344bb51fb4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireHeldToMaturitySecurities"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_03ecb7ab-57d1-433c-8db2-72344bb51fb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromLoansReceivable_895a4ebe-55e9-44df-b711-814e1e9b74d9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForProceedsFromLoansReceivable"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_PaymentsForProceedsFromLoansReceivable_895a4ebe-55e9-44df-b711-814e1e9b74d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PaymentsToAcquirePropertyPlantEquipmentAndSoftware_0beb36b5-b03e-4965-b59e-99d51e11846f" xlink:href="ntb-20201231.xsd#ntb_PaymentsToAcquirePropertyPlantEquipmentAndSoftware"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_ntb_PaymentsToAcquirePropertyPlantEquipmentAndSoftware_0beb36b5-b03e-4965-b59e-99d51e11846f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfOtherRealEstate_979a2531-36e3-4bdf-a1ea-90e58071c18e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfOtherRealEstate"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_ProceedsFromSaleOfOtherRealEstate_979a2531-36e3-4bdf-a1ea-90e58071c18e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireIntangibleAssets_96a775db-1cf7-4959-8cd1-31d52c75ba31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireIntangibleAssets"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_PaymentsToAcquireIntangibleAssets_96a775db-1cf7-4959-8cd1-31d52c75ba31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_fb4634b7-c6f4-4a8f-b2e7-10647301bc54" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_fb4634b7-c6f4-4a8f-b2e7-10647301bc54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_8617fe6e-3fc7-4034-a3d0-fc597bad9bae" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_8617fe6e-3fc7-4034-a3d0-fc597bad9bae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_528812d9-53bd-416d-a5e1-a8da22036a38" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_341dac8e-0ae3-4f40-a6ec-0294bae46a79" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_528812d9-53bd-416d-a5e1-a8da22036a38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInDeposits_6dcd940c-6dd2-4039-a4a4-3360ea4d75f4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInDeposits"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:to="loc_us-gaap_IncreaseDecreaseInDeposits_6dcd940c-6dd2-4039-a4a4-3360ea4d75f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSubordinatedLongTermDebt_0ede4bb8-727a-4e61-817b-a2100b2b94fb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfSubordinatedLongTermDebt"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSubordinatedLongTermDebt_0ede4bb8-727a-4e61-817b-a2100b2b94fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_516e7874-d09d-491c-9aad-a43cf3475bf7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_516e7874-d09d-491c-9aad-a43cf3475bf7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_6383110e-488a-4c82-bb30-a787de957d14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_6383110e-488a-4c82-bb30-a787de957d14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_320907cb-4a85-4df8-b7ef-8d5000344b10" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_320907cb-4a85-4df8-b7ef-8d5000344b10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_ae3fc81a-4857-4b12-9eef-65eb4d3961fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_ae3fc81a-4857-4b12-9eef-65eb4d3961fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_8a2454cd-53da-4491-bdde-ce0207a4ee8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_a54e9d7c-0815-4bb9-9faa-90b610c3b772" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_8a2454cd-53da-4491-bdde-ce0207a4ee8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4cc48145-2aa5-4146-82e2-91dd36064c1c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4cc48145-2aa5-4146-82e2-91dd36064c1c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_859c7ddb-6bb5-4fc7-9ede-16ddb498bdd3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_859c7ddb-6bb5-4fc7-9ede-16ddb498bdd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_37bc8022-5f6d-448a-8630-8c49c6504b19" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_37bc8022-5f6d-448a-8630-8c49c6504b19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_74f0b5ac-6c41-4bb9-a712-c6235a1cc928" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_74f0b5ac-6c41-4bb9-a712-c6235a1cc928" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_688609ed-c830-4676-862e-1f2a8a193f95" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_688609ed-c830-4676-862e-1f2a8a193f95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DueFromBanks_2d3bbd04-76bc-4543-81a0-902447d887c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DueFromBanks"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_688609ed-c830-4676-862e-1f2a8a193f95" xlink:to="loc_us-gaap_DueFromBanks_2d3bbd04-76bc-4543-81a0-902447d887c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_69cd235e-b574-4719-aa6a-b0de4e7e5da7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_688609ed-c830-4676-862e-1f2a8a193f95" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_69cd235e-b574-4719-aa6a-b0de4e7e5da7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7c733ca4-f6bb-4b11-82cb-ee9201736f5b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_688609ed-c830-4676-862e-1f2a8a193f95" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7c733ca4-f6bb-4b11-82cb-ee9201736f5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_4be478d3-218a-4f9c-ae0e-17015ff62335" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_4be478d3-218a-4f9c-ae0e-17015ff62335" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPaidNet_0286ef3d-ebcc-4fac-887e-93a016620f67" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestPaidNet"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_4be478d3-218a-4f9c-ae0e-17015ff62335" xlink:to="loc_us-gaap_InterestPaidNet_0286ef3d-ebcc-4fac-887e-93a016620f67" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxesPaidNet_97ec871b-c0c0-431b-aea2-4628ae98c452" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxesPaidNet"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_4be478d3-218a-4f9c-ae0e-17015ff62335" xlink:to="loc_us-gaap_IncomeTaxesPaidNet_97ec871b-c0c0-431b-aea2-4628ae98c452" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_e077a984-7252-42cf-86c1-1acf1396266d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_c29cef1e-d046-428a-8dac-35c7dba06c53" xlink:to="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_e077a984-7252-42cf-86c1-1acf1396266d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransferToOtherRealEstate_3b38ddac-bd55-4746-8d1a-2398a9baaaf8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransferToOtherRealEstate"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_e077a984-7252-42cf-86c1-1acf1396266d" xlink:to="loc_us-gaap_TransferToOtherRealEstate_3b38ddac-bd55-4746-8d1a-2398a9baaaf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransferOfOtherRealEstate_1accd6ce-25c9-42eb-b4e9-5f38a25fc4ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransferOfOtherRealEstate"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_e077a984-7252-42cf-86c1-1acf1396266d" xlink:to="loc_us-gaap_TransferOfOtherRealEstate_1accd6ce-25c9-42eb-b4e9-5f38a25fc4ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_RightofUseAssetAndLiabilityObtainedInExchangeForOperatingLeaseLiability_e6b5af2d-32f7-4583-bbd6-30827018ff10" xlink:href="ntb-20201231.xsd#ntb_RightofUseAssetAndLiabilityObtainedInExchangeForOperatingLeaseLiability"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_e077a984-7252-42cf-86c1-1acf1396266d" xlink:to="loc_ntb_RightofUseAssetAndLiabilityObtainedInExchangeForOperatingLeaseLiability_e6b5af2d-32f7-4583-bbd6-30827018ff10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LoansReduction_fab83045-e829-48e6-a21c-1bc6cefab890" xlink:href="ntb-20201231.xsd#ntb_LoansReduction"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_e077a984-7252-42cf-86c1-1acf1396266d" xlink:to="loc_ntb_LoansReduction_fab83045-e829-48e6-a21c-1bc6cefab890" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransferToInvestments_54a3898b-0f20-4727-8a86-26c4081e3539" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransferToInvestments"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_e077a984-7252-42cf-86c1-1acf1396266d" xlink:to="loc_us-gaap_TransferToInvestments_54a3898b-0f20-4727-8a86-26c4081e3539" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Natureofbusiness" xlink:type="simple" xlink:href="ntb-20201231.xsd#Natureofbusiness"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Natureofbusiness" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_cf91e059-7636-4402-9dac-8fe30ab086de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NatureOfOperations_549d2439-032b-47f4-9d07-44207622e9d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NatureOfOperations"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_cf91e059-7636-4402-9dac-8fe30ab086de" xlink:to="loc_us-gaap_NatureOfOperations_549d2439-032b-47f4-9d07-44207622e9d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/NatureofbusinessDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#NatureofbusinessDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/NatureofbusinessDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_99bca8ee-3b86-4f1c-87a9-39e63f17c24c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_1480ed79-6bbe-4ee3-8f72-bfe7ab0f9ed9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_99bca8ee-3b86-4f1c-87a9-39e63f17c24c" xlink:to="loc_us-gaap_NumberOfOperatingSegments_1480ed79-6bbe-4ee3-8f72-bfe7ab0f9ed9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Significantaccountingpolicies" xlink:type="simple" xlink:href="ntb-20201231.xsd#Significantaccountingpolicies"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Significantaccountingpolicies" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_990a8c26-9b78-4ec0-a82c-a9b8c84d8c11" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_3870c672-dc78-43e5-845d-b85c554a07d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_990a8c26-9b78-4ec0-a82c-a9b8c84d8c11" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_3870c672-dc78-43e5-845d-b85c554a07d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SignificantaccountingpoliciesPolicies" xlink:type="simple" xlink:href="ntb-20201231.xsd#SignificantaccountingpoliciesPolicies"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SignificantaccountingpoliciesPolicies" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_365f01e6-75b7-49ca-8a79-0a8027d00680" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_365f01e6-75b7-49ca-8a79-0a8027d00680" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_fc5a9915-d6ca-49f1-a4c1-c916cbca2fe1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UseOfEstimates"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_UseOfEstimates_fc5a9915-d6ca-49f1-a4c1-c916cbca2fe1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_61552d8f-a73c-4f92-9544-3be8569bd33f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_61552d8f-a73c-4f92-9544-3be8569bd33f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_f5d54dbf-200b-49e9-ad6a-5311a7cb6471" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_f5d54dbf-200b-49e9-ad6a-5311a7cb6471" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AssetsHeldinTrustorCustodyPolicyPolicyTextBlock_3214a611-9847-465e-b073-4e159f75f121" xlink:href="ntb-20201231.xsd#ntb_AssetsHeldinTrustorCustodyPolicyPolicyTextBlock"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_ntb_AssetsHeldinTrustorCustodyPolicyPolicyTextBlock_3214a611-9847-465e-b073-4e159f75f121" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_787d8277-41b8-45ea-9334-692582a62824" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_787d8277-41b8-45ea-9334-692582a62824" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepurchaseAndResaleAgreementsPolicy_510f54dc-a388-4e19-8eb7-2490a33cdf77" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepurchaseAndResaleAgreementsPolicy"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_RepurchaseAndResaleAgreementsPolicy_510f54dc-a388-4e19-8eb7-2490a33cdf77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentPolicyTextBlock_82a5229b-595a-4c85-934e-b627e1230d9a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentPolicyTextBlock"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_InvestmentPolicyTextBlock_82a5229b-595a-4c85-934e-b627e1230d9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLoansAndLeasesReceivablePolicy_2a6ee785-0979-4066-9e16-56a61e05e821" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLoansAndLeasesReceivablePolicy"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_FinanceLoansAndLeasesReceivablePolicy_2a6ee785-0979-4066-9e16-56a61e05e821" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesPolicyOrMethodologyChangePolicyTextBlock_d71fb491-d62e-4039-a7b2-c30878953b14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesPolicyOrMethodologyChangePolicyTextBlock"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesPolicyOrMethodologyChangePolicyTextBlock_d71fb491-d62e-4039-a7b2-c30878953b14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsPolicy_4f1300b7-cc02-48e1-90ae-56cee8b2957c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsPolicy"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_BusinessCombinationsPolicy_4f1300b7-cc02-48e1-90ae-56cee8b2957c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_9a54aeea-1026-4b52-ba9b-f22b6a3eac41" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_9a54aeea-1026-4b52-ba9b-f22b6a3eac41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_c6b28544-b9c4-4508-b88d-d6a22ccb6742" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_c6b28544-b9c4-4508-b88d-d6a22ccb6742" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealEstatePolicyTextBlock_e3c1d999-0198-4189-b985-475ded1877ab" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RealEstatePolicyTextBlock"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_RealEstatePolicyTextBlock_e3c1d999-0198-4189-b985-475ded1877ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_49afd4ba-c06c-453b-ae59-09cec3c60218" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeasesPolicyTextBlock"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_49afd4ba-c06c-453b-ae59-09cec3c60218" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesPolicyTextBlock_db8f57b4-afd8-4929-8f2e-4d4358b4ef90" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativesPolicyTextBlock"/>

<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_DerivativesPolicyTextBlock_db8f57b4-afd8-4929-8f2e-4d4358b4ef90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementPlansPolicy_f0428d5f-c070-496d-8947-d240b2a1cd61" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionAndOtherPostretirementPlansPolicy"/>

<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_PensionAndOtherPostretirementPlansPolicy_f0428d5f-c070-496d-8947-d240b2a1cd61" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_89d29c9b-f65f-4b61-b983-65a7b480d799" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy"/>

<link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_89d29c9b-f65f-4b61-b983-65a7b480d799" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_c57f4492-83e9-4b33-9b98-2c0b491e8244" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>

<link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_c57f4492-83e9-4b33-9b98-2c0b491e8244" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_459c18c3-39ad-45e4-9706-e1e7e8efb821" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock"/>

<link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_459c18c3-39ad-45e4-9706-e1e7e8efb821" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock_7f82f45b-1a81-4e00-8347-53db0c280e2e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock"/>

<link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock_7f82f45b-1a81-4e00-8347-53db0c280e2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskCreditRisk_886f6961-efe8-43c4-a83d-7c31092169dc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskCreditRisk"/>

<link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_ConcentrationRiskCreditRisk_886f6961-efe8-43c4-a83d-7c31092169dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_ba6aa3c3-1c70-48cc-9cff-5a3845ca1f08" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock"/>

<link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_ba6aa3c3-1c70-48cc-9cff-5a3845ca1f08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_5cdeefa0-c73f-469a-bf57-af7c04123c56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerSharePolicyTextBlock"/>

<link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_5cdeefa0-c73f-469a-bf57-af7c04123c56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_79e68eb4-cbd0-4986-9044-4b3f5c9615b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>

<link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_79e68eb4-cbd0-4986-9044-4b3f5c9615b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_cb5496a2-3685-4901-bfd6-bf5d5af386be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy"/>

<link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_667687d7-2b98-482a-ba56-2414914d6cb0" xlink:to="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_cb5496a2-3685-4901-bfd6-bf5d5af386be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SignificantaccountingpoliciesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SignificantaccountingpoliciesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SignificantaccountingpoliciesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_9d184f62-f98d-4a8f-8ea6-80fefad29bef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ThresholdContractualDaysPastDueConsumerLoans_44bdb749-1afa-4a18-b04a-b59b961c826d" xlink:href="ntb-20201231.xsd#ntb_ThresholdContractualDaysPastDueConsumerLoans"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9d184f62-f98d-4a8f-8ea6-80fefad29bef" xlink:to="loc_ntb_ThresholdContractualDaysPastDueConsumerLoans_44bdb749-1afa-4a18-b04a-b59b961c826d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ThresholdOutstandingBalanceConsumerLoans_74983bf6-64b4-4908-a7bb-e31a87683a00" xlink:href="ntb-20201231.xsd#ntb_ThresholdOutstandingBalanceConsumerLoans"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9d184f62-f98d-4a8f-8ea6-80fefad29bef" xlink:to="loc_ntb_ThresholdOutstandingBalanceConsumerLoans_74983bf6-64b4-4908-a7bb-e31a87683a00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ThresholdContractualDaysPastDueConsumerLoansBalanceUnder100000_a3661581-2185-4097-97d4-a1ea6d073421" xlink:href="ntb-20201231.xsd#ntb_ThresholdContractualDaysPastDueConsumerLoansBalanceUnder100000"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9d184f62-f98d-4a8f-8ea6-80fefad29bef" xlink:to="loc_ntb_ThresholdContractualDaysPastDueConsumerLoansBalanceUnder100000_a3661581-2185-4097-97d4-a1ea6d073421" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9d184f62-f98d-4a8f-8ea6-80fefad29bef" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_2de3ac44-a54a-4bb1-834b-0cf842c94d0c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_2de3ac44-a54a-4bb1-834b-0cf842c94d0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_34347e63-9d49-452e-9f14-bafef4263121" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_2de3ac44-a54a-4bb1-834b-0cf842c94d0c" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_34347e63-9d49-452e-9f14-bafef4263121" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIntangibleAssetsMember_7e46aa23-7338-4841-8680-083c3f4920a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherIntangibleAssetsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_34347e63-9d49-452e-9f14-bafef4263121" xlink:to="loc_us-gaap_OtherIntangibleAssetsMember_7e46aa23-7338-4841-8680-083c3f4920a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_dea3665a-00c3-4cbb-a36e-a361d75f38be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_dea3665a-00c3-4cbb-a36e-a361d75f38be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_a7019412-6fe1-4f62-99c1-3508914f31d9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_dea3665a-00c3-4cbb-a36e-a361d75f38be" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_a7019412-6fe1-4f62-99c1-3508914f31d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BuildingMember_47e9546b-8ed0-4405-80fb-5dbedc0472ea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BuildingMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_a7019412-6fe1-4f62-99c1-3508914f31d9" xlink:to="loc_us-gaap_BuildingMember_47e9546b-8ed0-4405-80fb-5dbedc0472ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquipmentMember_d9b0ed62-65d6-4757-9457-f1292c1a2b8d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquipmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_a7019412-6fe1-4f62-99c1-3508914f31d9" xlink:to="loc_us-gaap_EquipmentMember_d9b0ed62-65d6-4757-9457-f1292c1a2b8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SoftwareAndSoftwareDevelopmentCostsMember_f42a7bf2-fa16-4731-9617-ca790949e71c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SoftwareAndSoftwareDevelopmentCostsMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_a7019412-6fe1-4f62-99c1-3508914f31d9" xlink:to="loc_us-gaap_SoftwareAndSoftwareDevelopmentCostsMember_f42a7bf2-fa16-4731-9617-ca790949e71c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_76ec793b-d771-459b-822c-0e2cbe5e0505" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:to="loc_srt_RangeAxis_76ec793b-d771-459b-822c-0e2cbe5e0505" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_b4fa4c67-f9b9-4152-b8ef-ba56f3e49f10" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_76ec793b-d771-459b-822c-0e2cbe5e0505" xlink:to="loc_srt_RangeMember_b4fa4c67-f9b9-4152-b8ef-ba56f3e49f10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_ff3635ad-e015-4579-9579-c1fa74aa11f5" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_b4fa4c67-f9b9-4152-b8ef-ba56f3e49f10" xlink:to="loc_srt_MinimumMember_ff3635ad-e015-4579-9579-c1fa74aa11f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_f93e59c4-8856-4ecb-a947-3fed54bfab65" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_b4fa4c67-f9b9-4152-b8ef-ba56f3e49f10" xlink:to="loc_srt_MaximumMember_f93e59c4-8856-4ecb-a947-3fed54bfab65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_be7346a5-397b-4420-9770-16953918f51e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_be7346a5-397b-4420-9770-16953918f51e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_43fbad3c-0db5-4495-a6ff-eb852793ff2d" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_be7346a5-397b-4420-9770-16953918f51e" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_43fbad3c-0db5-4495-a6ff-eb852793ff2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_758a3373-05a8-4064-a023-2745553306f2" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_43fbad3c-0db5-4495-a6ff-eb852793ff2d" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_758a3373-05a8-4064-a023-2745553306f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_e9eddb81-e425-46ed-b973-d0c17ebb5e34" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_e9eddb81-e425-46ed-b973-d0c17ebb5e34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_c9f54dc6-5188-4310-87eb-e6fe8c60e4d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_e9eddb81-e425-46ed-b973-d0c17ebb5e34" xlink:to="loc_us-gaap_EquityComponentDomain_c9f54dc6-5188-4310-87eb-e6fe8c60e4d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_659de73f-86fe-4d54-9050-31c69fa6cd4e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_c9f54dc6-5188-4310-87eb-e6fe8c60e4d3" xlink:to="loc_us-gaap_RetainedEarningsMember_659de73f-86fe-4d54-9050-31c69fa6cd4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7eb7edac-230b-4501-aaa5-ee7782244965" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_9b8b624b-6774-4489-ac4a-4eaebd467185" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7eb7edac-230b-4501-aaa5-ee7782244965" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_da64b6dc-a812-46a4-ad0b-6e6b774def36" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7eb7edac-230b-4501-aaa5-ee7782244965" xlink:to="loc_us-gaap_StockholdersEquity_da64b6dc-a812-46a4-ad0b-6e6b774def36" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_39ed3b97-2be2-4d42-af5a-3bc45fd1394c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7eb7edac-230b-4501-aaa5-ee7782244965" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_39ed3b97-2be2-4d42-af5a-3bc45fd1394c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_9d568eef-37be-41f9-9814-2c34ecdd9dc5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7eb7edac-230b-4501-aaa5-ee7782244965" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_9d568eef-37be-41f9-9814-2c34ecdd9dc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Cashduefrombanks" xlink:type="simple" xlink:href="ntb-20201231.xsd#Cashduefrombanks"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Cashduefrombanks" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAbstract_afe98bd9-9237-45c1-82b3-a3d626f86891" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsDisclosureTextBlock_db3dfcef-a005-42bd-bd3c-9f968d612215" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_afe98bd9-9237-45c1-82b3-a3d626f86891" xlink:to="loc_us-gaap_CashAndCashEquivalentsDisclosureTextBlock_db3dfcef-a005-42bd-bd3c-9f968d612215" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CashduefrombanksTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#CashduefrombanksTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CashduefrombanksTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAbstract_a2aa5898-9a84-47de-b2f0-dc6f4be4bc93" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_9ecf14a2-ea78-428b-97f3-6e93a41ca911" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_a2aa5898-9a84-47de-b2f0-dc6f4be4bc93" xlink:to="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_9ecf14a2-ea78-428b-97f3-6e93a41ca911" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CashduefrombanksDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CashduefrombanksDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CashduefrombanksDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAbstract_7dffd1cb-4692-4883-850c-0595bd44af22" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndDueFromBanksAbstract_6cd90bab-18e3-4ced-a0ee-dc7c26574164" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndDueFromBanksAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_7dffd1cb-4692-4883-850c-0595bd44af22" xlink:to="loc_us-gaap_CashAndDueFromBanksAbstract_6cd90bab-18e3-4ced-a0ee-dc7c26574164" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndDueFromBanks_60a80aeb-cc9a-41c6-bdfa-1b336f1edea5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndDueFromBanks"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndDueFromBanksAbstract_6cd90bab-18e3-4ced-a0ee-dc7c26574164" xlink:to="loc_us-gaap_CashAndDueFromBanks_60a80aeb-cc9a-41c6-bdfa-1b336f1edea5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CashandDuefromBanksInterestbearingAbstract_7677886a-e87d-406d-929e-a6f7e866c4d2" xlink:href="ntb-20201231.xsd#ntb_CashandDuefromBanksInterestbearingAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_7dffd1cb-4692-4883-850c-0595bd44af22" xlink:to="loc_ntb_CashandDuefromBanksInterestbearingAbstract_7677886a-e87d-406d-929e-a6f7e866c4d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositsInBanks_4df231eb-7053-40a1-8a76-1ba4887b29d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestBearingDepositsInBanks"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_CashandDuefromBanksInterestbearingAbstract_7677886a-e87d-406d-929e-a6f7e866c4d2" xlink:to="loc_us-gaap_InterestBearingDepositsInBanks_4df231eb-7053-40a1-8a76-1ba4887b29d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashEquivalentsAtCarryingValue_17307063-73e3-4a3f-bcb9-2d89a3c9f3d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashEquivalentsAtCarryingValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_CashandDuefromBanksInterestbearingAbstract_7677886a-e87d-406d-929e-a6f7e866c4d2" xlink:to="loc_us-gaap_CashEquivalentsAtCarryingValue_17307063-73e3-4a3f-bcb9-2d89a3c9f3d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InterestBearingDepositsInBanksAndOtherFinancialInstitutionsAndCashEquivalentsCarryingValue_1a066292-19f7-4a8c-b3ca-f1457b8cbf88" xlink:href="ntb-20201231.xsd#ntb_InterestBearingDepositsInBanksAndOtherFinancialInstitutionsAndCashEquivalentsCarryingValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_CashandDuefromBanksInterestbearingAbstract_7677886a-e87d-406d-929e-a6f7e866c4d2" xlink:to="loc_ntb_InterestBearingDepositsInBanksAndOtherFinancialInstitutionsAndCashEquivalentsCarryingValue_1a066292-19f7-4a8c-b3ca-f1457b8cbf88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_030718b6-b13d-42be-9824-b3bb228f91df" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_7dffd1cb-4692-4883-850c-0595bd44af22" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_030718b6-b13d-42be-9824-b3bb228f91df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InterestbearingDepositsinBanksandOtherFinancialInstitutionsBearingNegligibleInterest_2751b97d-b944-4368-bb1e-94f01a6257fb" xlink:href="ntb-20201231.xsd#ntb_InterestbearingDepositsinBanksandOtherFinancialInstitutionsBearingNegligibleInterest"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_7dffd1cb-4692-4883-850c-0595bd44af22" xlink:to="loc_ntb_InterestbearingDepositsinBanksandOtherFinancialInstitutionsBearingNegligibleInterest_2751b97d-b944-4368-bb1e-94f01a6257fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Shortterminvestments" xlink:type="simple" xlink:href="ntb-20201231.xsd#Shortterminvestments"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Shortterminvestments" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_696578ac-f0b5-4530-8e2e-2eb359e94306" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestmentsTextBlock_ba92253f-d42c-477f-b6f4-8134db7d47a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestmentsTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_696578ac-f0b5-4530-8e2e-2eb359e94306" xlink:to="loc_us-gaap_CashCashEquivalentsAndShortTermInvestmentsTextBlock_ba92253f-d42c-477f-b6f4-8134db7d47a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ShortterminvestmentsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#ShortterminvestmentsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ShortterminvestmentsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_8a9f01a8-79b9-47be-847c-92e41f4e41a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock_af6e4588-946f-4f7b-86d4-1332a468e6bb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_8a9f01a8-79b9-47be-847c-92e41f4e41a5" xlink:to="loc_us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock_af6e4588-946f-4f7b-86d4-1332a468e6bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/ShortterminvestmentsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#ShortterminvestmentsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/ShortterminvestmentsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_deb39205-0af6-4738-92f9-acfcf733c923" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentHoldingsTable_8b0fe692-0503-464c-ac30-0afb5014f121" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentHoldingsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_deb39205-0af6-4738-92f9-acfcf733c923" xlink:to="loc_us-gaap_InvestmentHoldingsTable_8b0fe692-0503-464c-ac30-0afb5014f121" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentsMaturityPeriodAxis_ce6db826-80d6-45a2-867a-e94886d2750b" xlink:href="ntb-20201231.xsd#ntb_InvestmentsMaturityPeriodAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentHoldingsTable_8b0fe692-0503-464c-ac30-0afb5014f121" xlink:to="loc_ntb_InvestmentsMaturityPeriodAxis_ce6db826-80d6-45a2-867a-e94886d2750b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentsMaturityPeriodDomain_8c92ee76-9421-4537-9f07-5c08f3f4a855" xlink:href="ntb-20201231.xsd#ntb_InvestmentsMaturityPeriodDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentsMaturityPeriodAxis_ce6db826-80d6-45a2-867a-e94886d2750b" xlink:to="loc_ntb_InvestmentsMaturityPeriodDomain_8c92ee76-9421-4537-9f07-5c08f3f4a855" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_MaturingWithinThreeMonthsMember_c0ca6353-3a36-4710-81f2-e11ff02898f7" xlink:href="ntb-20201231.xsd#ntb_MaturingWithinThreeMonthsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentsMaturityPeriodDomain_8c92ee76-9421-4537-9f07-5c08f3f4a855" xlink:to="loc_ntb_MaturingWithinThreeMonthsMember_c0ca6353-3a36-4710-81f2-e11ff02898f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_MaturingBetweenThreeToSixMonthsMember_4982e6e0-016e-4a08-93d3-00d0ab8a7050" xlink:href="ntb-20201231.xsd#ntb_MaturingBetweenThreeToSixMonthsMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentsMaturityPeriodDomain_8c92ee76-9421-4537-9f07-5c08f3f4a855" xlink:to="loc_ntb_MaturingBetweenThreeToSixMonthsMember_4982e6e0-016e-4a08-93d3-00d0ab8a7050" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_MaturingBetweenSixToTwelveMonthsMember_dc8d1cb6-b4e0-46bc-a067-3ed721fa6699" xlink:href="ntb-20201231.xsd#ntb_MaturingBetweenSixToTwelveMonthsMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentsMaturityPeriodDomain_8c92ee76-9421-4537-9f07-5c08f3f4a855" xlink:to="loc_ntb_MaturingBetweenSixToTwelveMonthsMember_dc8d1cb6-b4e0-46bc-a067-3ed721fa6699" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis_f0a9e181-abc4-4a8f-95d9-f405c7e55c17" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentHoldingsTable_8b0fe692-0503-464c-ac30-0afb5014f121" xlink:to="loc_us-gaap_InvestmentTypeAxis_f0a9e181-abc4-4a8f-95d9-f405c7e55c17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_0d0ac63e-b79c-4d98-8e1b-9952f9c57f52" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeAxis_f0a9e181-abc4-4a8f-95d9-f405c7e55c17" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_0d0ac63e-b79c-4d98-8e1b-9952f9c57f52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_UnrestrictedInvestmentsMember_1221ef92-360d-4b49-93ba-0f293f47aee6" xlink:href="ntb-20201231.xsd#ntb_UnrestrictedInvestmentsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_0d0ac63e-b79c-4d98-8e1b-9952f9c57f52" xlink:to="loc_ntb_UnrestrictedInvestmentsMember_1221ef92-360d-4b49-93ba-0f293f47aee6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_RestrictedInvestmentsMember_f639a65a-4ba1-4f3e-9fe5-94f6880d7fa2" xlink:href="ntb-20201231.xsd#ntb_RestrictedInvestmentsMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_0d0ac63e-b79c-4d98-8e1b-9952f9c57f52" xlink:to="loc_ntb_RestrictedInvestmentsMember_f639a65a-4ba1-4f3e-9fe5-94f6880d7fa2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByAssetClassAxis_f35c776f-1252-45c6-808e-6aff262a1354" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByAssetClassAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentHoldingsTable_8b0fe692-0503-464c-ac30-0afb5014f121" xlink:to="loc_us-gaap_FairValueByAssetClassAxis_f35c776f-1252-45c6-808e-6aff262a1354" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_010166d6-25ff-4eb1-9f3b-074925d7372a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByAssetClassAxis_f35c776f-1252-45c6-808e-6aff262a1354" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_010166d6-25ff-4eb1-9f3b-074925d7372a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NonInterestBearingDepositsMember_32da4ff2-ed1d-4975-84f3-15547614ce81" xlink:href="ntb-20201231.xsd#ntb_NonInterestBearingDepositsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_010166d6-25ff-4eb1-9f3b-074925d7372a" xlink:to="loc_ntb_NonInterestBearingDepositsMember_32da4ff2-ed1d-4975-84f3-15547614ce81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositsMember_025f7c18-9330-47a6-8707-2d4610bac3f5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestBearingDepositsMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_010166d6-25ff-4eb1-9f3b-074925d7372a" xlink:to="loc_us-gaap_InterestBearingDepositsMember_025f7c18-9330-47a6-8707-2d4610bac3f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentHoldingsLineItems_2d512bfd-2a1e-4d77-a635-62c27c1df4ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentHoldingsLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentHoldingsTable_8b0fe692-0503-464c-ac30-0afb5014f121" xlink:to="loc_us-gaap_InvestmentHoldingsLineItems_2d512bfd-2a1e-4d77-a635-62c27c1df4ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherShortTermInvestments_2df24bde-3eac-4c68-b61b-09d7f88bccd3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherShortTermInvestments"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentHoldingsLineItems_2d512bfd-2a1e-4d77-a635-62c27c1df4ee" xlink:to="loc_us-gaap_OtherShortTermInvestments_2df24bde-3eac-4c68-b61b-09d7f88bccd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Investmentinsecurities" xlink:type="simple" xlink:href="ntb-20201231.xsd#Investmentinsecurities"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Investmentinsecurities" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_8803ab77-3ce6-421a-b6a5-c007ffe99c5a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_3a9b19c6-6b37-4730-86dd-10d5ae6573a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_8803ab77-3ce6-421a-b6a5-c007ffe99c5a" xlink:to="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_3a9b19c6-6b37-4730-86dd-10d5ae6573a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#InvestmentinsecuritiesTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_e0a0f69e-c145-47a8-9a43-be8f53aab475" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecuritiesTextBlock_9461b906-aa50-43fe-a601-e183de59916a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketableSecuritiesTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_e0a0f69e-c145-47a8-9a43-be8f53aab475" xlink:to="loc_us-gaap_MarketableSecuritiesTextBlock_9461b906-aa50-43fe-a601-e183de59916a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_ad8512f0-0af5-4909-b6c4-c6cf5b1cc3f5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_e0a0f69e-c145-47a8-9a43-be8f53aab475" xlink:to="loc_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock_ad8512f0-0af5-4909-b6c4-c6cf5b1cc3f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRealizedGainLossTableTextBlock_665d2b6e-2efa-404f-bf98-ceea2e310f34" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRealizedGainLossTableTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_e0a0f69e-c145-47a8-9a43-be8f53aab475" xlink:to="loc_us-gaap_ScheduleOfRealizedGainLossTableTextBlock_665d2b6e-2efa-404f-bf98-ceea2e310f34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesAmortizedCostCarryingAmountandFairValueDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#InvestmentinsecuritiesAmortizedCostCarryingAmountandFairValueDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesAmortizedCostCarryingAmountandFairValueDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_627f4f50-4928-485d-aa57-c66433a9d8fc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ScheduleOfMarketableSecuritiesTable_f84c7ff7-16df-41fc-84b7-eb6b1da4da31" xlink:href="ntb-20201231.xsd#ntb_ScheduleOfMarketableSecuritiesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_627f4f50-4928-485d-aa57-c66433a9d8fc" xlink:to="loc_ntb_ScheduleOfMarketableSecuritiesTable_f84c7ff7-16df-41fc-84b7-eb6b1da4da31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_7e79a375-9d17-4742-9d3a-86d081bae87f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesTable_f84c7ff7-16df-41fc-84b7-eb6b1da4da31" xlink:to="loc_us-gaap_FinancialInstrumentAxis_7e79a375-9d17-4742-9d3a-86d081bae87f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1ed2483b-9ae9-44ff-b711-d84eb4eefed2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_7e79a375-9d17-4742-9d3a-86d081bae87f" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1ed2483b-9ae9-44ff-b711-d84eb4eefed2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesMember_d8c9328b-93e1-44cb-ba5d-35a8b86fb6dd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1ed2483b-9ae9-44ff-b711-d84eb4eefed2" xlink:to="loc_us-gaap_EquitySecuritiesMember_d8c9328b-93e1-44cb-ba5d-35a8b86fb6dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryAndGovernmentMember_8243eaac-911a-45fb-b648-0ff7bef14c20" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USTreasuryAndGovernmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1ed2483b-9ae9-44ff-b711-d84eb4eefed2" xlink:to="loc_us-gaap_USTreasuryAndGovernmentMember_8243eaac-911a-45fb-b648-0ff7bef14c20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_3cf1f636-7bdb-4a77-91d0-9d9fad39a709" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1ed2483b-9ae9-44ff-b711-d84eb4eefed2" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_3cf1f636-7bdb-4a77-91d0-9d9fad39a709" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AssetbackedSecuritiesStudentLoansMember_56389a00-1b8d-4e05-9be7-6b6a16ce56c9" xlink:href="ntb-20201231.xsd#ntb_AssetbackedSecuritiesStudentLoansMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1ed2483b-9ae9-44ff-b711-d84eb4eefed2" xlink:to="loc_ntb_AssetbackedSecuritiesStudentLoansMember_56389a00-1b8d-4e05-9be7-6b6a16ce56c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_906ac9a0-80c4-4020-98c0-0ba866a5d271" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1ed2483b-9ae9-44ff-b711-d84eb4eefed2" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_906ac9a0-80c4-4020-98c0-0ba866a5d271" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_4b820448-8c8e-4f7c-8876-bdc2cf528bd8" xlink:href="ntb-20201231.xsd#ntb_ScheduleOfMarketableSecuritiesLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesTable_f84c7ff7-16df-41fc-84b7-eb6b1da4da31" xlink:to="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_4b820448-8c8e-4f7c-8876-bdc2cf528bd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesTradingAndEquitySecuritiesFvNiAbstract_86a1114a-14fc-4634-9414-573ff5e06fa1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesTradingAndEquitySecuritiesFvNiAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_4b820448-8c8e-4f7c-8876-bdc2cf528bd8" xlink:to="loc_us-gaap_DebtSecuritiesTradingAndEquitySecuritiesFvNiAbstract_86a1114a-14fc-4634-9414-573ff5e06fa1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiCost_ee3520af-1bd3-4929-b64d-b7abb93b4314" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNiCost"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesTradingAndEquitySecuritiesFvNiAbstract_86a1114a-14fc-4634-9414-573ff5e06fa1" xlink:to="loc_us-gaap_EquitySecuritiesFvNiCost_ee3520af-1bd3-4929-b64d-b7abb93b4314" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EquitySecuritiesFVNIAccumulatedGrossUnrealizedGainbeforeTax_29205e5b-9e7c-4a86-9bae-e2c8552571f7" xlink:href="ntb-20201231.xsd#ntb_EquitySecuritiesFVNIAccumulatedGrossUnrealizedGainbeforeTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesTradingAndEquitySecuritiesFvNiAbstract_86a1114a-14fc-4634-9414-573ff5e06fa1" xlink:to="loc_ntb_EquitySecuritiesFVNIAccumulatedGrossUnrealizedGainbeforeTax_29205e5b-9e7c-4a86-9bae-e2c8552571f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EquitySecuritiesFVNIAccumulatedGrossUnrealizedLossbeforeTax_68101820-970f-4c33-ad2c-869e22f02d4b" xlink:href="ntb-20201231.xsd#ntb_EquitySecuritiesFVNIAccumulatedGrossUnrealizedLossbeforeTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesTradingAndEquitySecuritiesFvNiAbstract_86a1114a-14fc-4634-9414-573ff5e06fa1" xlink:to="loc_ntb_EquitySecuritiesFVNIAccumulatedGrossUnrealizedLossbeforeTax_68101820-970f-4c33-ad2c-869e22f02d4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_c09c1546-f21a-4630-8d2e-5e15a85c87e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesTradingAndEquitySecuritiesFvNiAbstract_86a1114a-14fc-4634-9414-573ff5e06fa1" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_c09c1546-f21a-4630-8d2e-5e15a85c87e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAbstract_94239a05-2c73-4f20-b31f-0ff9f55fc421" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_4b820448-8c8e-4f7c-8876-bdc2cf528bd8" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesAbstract_94239a05-2c73-4f20-b31f-0ff9f55fc421" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_571d1e09-3497-4b57-9b42-436293751a2e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_94239a05-2c73-4f20-b31f-0ff9f55fc421" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_571d1e09-3497-4b57-9b42-436293751a2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_58c40965-db0b-467d-b97c-a14873c81e8d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_94239a05-2c73-4f20-b31f-0ff9f55fc421" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_58c40965-db0b-467d-b97c-a14873c81e8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_38663fcc-d6be-4100-b4d6-69512665998a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_94239a05-2c73-4f20-b31f-0ff9f55fc421" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_38663fcc-d6be-4100-b4d6-69512665998a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_66f2945b-9a6c-4566-a551-1ac31d475594" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_94239a05-2c73-4f20-b31f-0ff9f55fc421" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_66f2945b-9a6c-4566-a551-1ac31d475594" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAbstract_c8384cbf-651f-4097-b877-a3498664f58c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_4b820448-8c8e-4f7c-8876-bdc2cf528bd8" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAbstract_c8384cbf-651f-4097-b877-a3498664f58c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecurities_b412eb18-ee20-4689-a0b2-cb74e67d8f74" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecurities"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_c8384cbf-651f-4097-b877-a3498664f58c" xlink:to="loc_us-gaap_HeldToMaturitySecurities_b412eb18-ee20-4689-a0b2-cb74e67d8f74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_c0d36ce1-bb99-4e14-b009-984a26cb5865" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_c8384cbf-651f-4097-b877-a3498664f58c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_c0d36ce1-bb99-4e14-b009-984a26cb5865" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_45cf4096-76da-48d4-b85a-ef66a1791a5e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_c8384cbf-651f-4097-b877-a3498664f58c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_45cf4096-76da-48d4-b85a-ef66a1791a5e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_4c26ecc7-270a-4cd2-9d49-313b10d67002" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesFairValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_c8384cbf-651f-4097-b877-a3498664f58c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesFairValue_4c26ecc7-270a-4cd2-9d49-313b10d67002" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherThanTemporaryImpairmentLossesInvestmentsPortionInOtherComprehensiveIncomeLossBeforeTaxIncludingPortionAttributableToNoncontrollingInterestHeldtomaturitySecurities_9f7ee282-0cbd-4882-8604-5f6e9354c6bb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherThanTemporaryImpairmentLossesInvestmentsPortionInOtherComprehensiveIncomeLossBeforeTaxIncludingPortionAttributableToNoncontrollingInterestHeldtomaturitySecurities"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_4b820448-8c8e-4f7c-8876-bdc2cf528bd8" xlink:to="loc_us-gaap_OtherThanTemporaryImpairmentLossesInvestmentsPortionInOtherComprehensiveIncomeLossBeforeTaxIncludingPortionAttributableToNoncontrollingInterestHeldtomaturitySecurities_9f7ee282-0cbd-4882-8604-5f6e9354c6bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesNarrativeDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#InvestmentinsecuritiesNarrativeDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesNarrativeDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_5771d0a4-596c-441a-b8d5-24fce896a4b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_81307b62-93a1-477b-b73b-20ab210a0a6a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_5771d0a4-596c-441a-b8d5-24fce896a4b4" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_81307b62-93a1-477b-b73b-20ab210a0a6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_875171a1-86f2-492f-be6a-325203063b46" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_81307b62-93a1-477b-b73b-20ab210a0a6a" xlink:to="loc_us-gaap_FinancialInstrumentAxis_875171a1-86f2-492f-be6a-325203063b46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ed7d63ed-0abb-499b-9842-eaba4c458179" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_875171a1-86f2-492f-be6a-325203063b46" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ed7d63ed-0abb-499b-9842-eaba4c458179" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryAndGovernmentMember_fd6cbc08-48bd-4f91-b499-b651c365e32d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USTreasuryAndGovernmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ed7d63ed-0abb-499b-9842-eaba4c458179" xlink:to="loc_us-gaap_USTreasuryAndGovernmentMember_fd6cbc08-48bd-4f91-b499-b651c365e32d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_5f7ee86c-4abf-498b-946e-3f50f76cd4f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_ed7d63ed-0abb-499b-9842-eaba4c458179" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_5f7ee86c-4abf-498b-946e-3f50f76cd4f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_81307b62-93a1-477b-b73b-20ab210a0a6a" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionNumberOfPositions_bbe35944-9c64-4c85-8e5a-6abd78606b09" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionNumberOfPositions"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionNumberOfPositions_bbe35944-9c64-4c85-8e5a-6abd78606b09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DebtSecuritiesAvailableForSaleSecuritiesInUnrealizedLossPositionsPercentageOfPortfolioFairValue_6436049c-abdd-43b8-856c-203954434f8d" xlink:href="ntb-20201231.xsd#ntb_DebtSecuritiesAvailableForSaleSecuritiesInUnrealizedLossPositionsPercentageOfPortfolioFairValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:to="loc_ntb_DebtSecuritiesAvailableForSaleSecuritiesInUnrealizedLossPositionsPercentageOfPortfolioFairValue_6436049c-abdd-43b8-856c-203954434f8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DebtSecuritiesAvailableForSaleSecuritiesInUnrealizedLossPositionsPercentageOfFairValueOfAffectedSecurities_7fc86bf6-1996-44b6-bd59-b998137113d5" xlink:href="ntb-20201231.xsd#ntb_DebtSecuritiesAvailableForSaleSecuritiesInUnrealizedLossPositionsPercentageOfFairValueOfAffectedSecurities"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:to="loc_ntb_DebtSecuritiesAvailableForSaleSecuritiesInUnrealizedLossPositionsPercentageOfFairValueOfAffectedSecurities_7fc86bf6-1996-44b6-bd59-b998137113d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions_62376cba-f39f-40fb-9865-064c40bc0784" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions_62376cba-f39f-40fb-9865-064c40bc0784" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_HeldToMaturitySecuritiesInUnrealizedLossPositionsPercentageOfPortfolioFairValue_10f87bb9-2863-40cf-b96e-5eb3dea99028" xlink:href="ntb-20201231.xsd#ntb_HeldToMaturitySecuritiesInUnrealizedLossPositionsPercentageOfPortfolioFairValue"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:to="loc_ntb_HeldToMaturitySecuritiesInUnrealizedLossPositionsPercentageOfPortfolioFairValue_10f87bb9-2863-40cf-b96e-5eb3dea99028" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_HeldToMaturitySecuritiesInUnrealizedLossPositionsPercentageOfFairValueOfAffectedSecurities_f3eca7bb-368a-43b8-9a92-1b7f8861b792" xlink:href="ntb-20201231.xsd#ntb_HeldToMaturitySecuritiesInUnrealizedLossPositionsPercentageOfFairValueOfAffectedSecurities"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_4573b860-0335-4260-ab45-35fb2fc93ca2" xlink:to="loc_ntb_HeldToMaturitySecuritiesInUnrealizedLossPositionsPercentageOfFairValueOfAffectedSecurities_f3eca7bb-368a-43b8-9a92-1b7f8861b792" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesContinuousUnrealizedLossPositionDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#InvestmentinsecuritiesContinuousUnrealizedLossPositionDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesContinuousUnrealizedLossPositionDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_4b0adcb7-0f42-43d5-ad78-00b19ac590b3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ScheduleOfMarketableSecuritiesTable_4c70b788-8e77-4cf9-a063-749bd8579e66" xlink:href="ntb-20201231.xsd#ntb_ScheduleOfMarketableSecuritiesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_4b0adcb7-0f42-43d5-ad78-00b19ac590b3" xlink:to="loc_ntb_ScheduleOfMarketableSecuritiesTable_4c70b788-8e77-4cf9-a063-749bd8579e66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_e0aa2928-408f-4cc6-a049-66c79537a624" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesTable_4c70b788-8e77-4cf9-a063-749bd8579e66" xlink:to="loc_us-gaap_FinancialInstrumentAxis_e0aa2928-408f-4cc6-a049-66c79537a624" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_74fc26b6-b3fe-4e8d-8e26-bc85c40f7b99" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_e0aa2928-408f-4cc6-a049-66c79537a624" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_74fc26b6-b3fe-4e8d-8e26-bc85c40f7b99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryAndGovernmentMember_c905de09-9bdc-452e-83c0-3d38b98fbf38" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USTreasuryAndGovernmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_74fc26b6-b3fe-4e8d-8e26-bc85c40f7b99" xlink:to="loc_us-gaap_USTreasuryAndGovernmentMember_c905de09-9bdc-452e-83c0-3d38b98fbf38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_28d14c8d-1710-4d2d-afc0-9349bbc7d12f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_74fc26b6-b3fe-4e8d-8e26-bc85c40f7b99" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_28d14c8d-1710-4d2d-afc0-9349bbc7d12f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AssetbackedSecuritiesStudentLoansMember_0037c444-cbe8-4f6d-a231-f43f7697b297" xlink:href="ntb-20201231.xsd#ntb_AssetbackedSecuritiesStudentLoansMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_74fc26b6-b3fe-4e8d-8e26-bc85c40f7b99" xlink:to="loc_ntb_AssetbackedSecuritiesStudentLoansMember_0037c444-cbe8-4f6d-a231-f43f7697b297" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_43653db2-9060-4e61-9815-cdae8027739b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_74fc26b6-b3fe-4e8d-8e26-bc85c40f7b99" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_43653db2-9060-4e61-9815-cdae8027739b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:href="ntb-20201231.xsd#ntb_ScheduleOfMarketableSecuritiesLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesTable_4c70b788-8e77-4cf9-a063-749bd8579e66" xlink:to="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months_a6eeabc2-4cd2-4971-b2a6-ebe4d77a45c2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months_a6eeabc2-4cd2-4971-b2a6-ebe4d77a45c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_316fcd83-416f-4ce2-9c41-dabe6b0450ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_316fcd83-416f-4ce2-9c41-dabe6b0450ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger_5048fbf2-f973-46aa-93f6-74b407a8da48" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger_5048fbf2-f973-46aa-93f6-74b407a8da48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_bbea65fa-6c69-4193-9cc1-5b8d2a32b1a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_bbea65fa-6c69-4193-9cc1-5b8d2a32b1a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_7038a329-d5b9-4ac5-b1cc-8d9fcf8a8137" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_7038a329-d5b9-4ac5-b1cc-8d9fcf8a8137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_f4d2caeb-2847-4e81-9c42-0dcac5f1c834" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_f4d2caeb-2847-4e81-9c42-0dcac5f1c834" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue_811d31ee-a01a-4403-8d72-547764da6d5c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue_811d31ee-a01a-4403-8d72-547764da6d5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_d67bbf03-944d-409d-9051-15ddf28366aa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_d67bbf03-944d-409d-9051-15ddf28366aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue_dc1f72f4-b740-4ce1-87a3-41487df772fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue_dc1f72f4-b740-4ce1-87a3-41487df772fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_7e6f81b3-9183-4c5c-b268-8ffc2d143c58" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_7e6f81b3-9183-4c5c-b268-8ffc2d143c58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionFairValue_6be441bb-c32a-4498-a664-d2b5d9556617" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionFairValue"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionFairValue_6be441bb-c32a-4498-a664-d2b5d9556617" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionAccumulatedLoss_65fd4a94-bd35-4683-8af6-cfb6d2d1c902" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionAccumulatedLoss"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_15b643a5-c7c4-4e38-af3e-26ba96afb9e4" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionAccumulatedLoss_65fd4a94-bd35-4683-8af6-cfb6d2d1c902" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesInvestmentMaturitiesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#InvestmentinsecuritiesInvestmentMaturitiesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesInvestmentMaturitiesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_698c77ed-8dba-4e1d-9ee9-979b8ad81262" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ScheduleOfMarketableSecuritiesTable_ea4592f0-821a-4a35-9322-351082aa4087" xlink:href="ntb-20201231.xsd#ntb_ScheduleOfMarketableSecuritiesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_698c77ed-8dba-4e1d-9ee9-979b8ad81262" xlink:to="loc_ntb_ScheduleOfMarketableSecuritiesTable_ea4592f0-821a-4a35-9322-351082aa4087" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_2de2003e-fe4f-4931-b70f-f5b177cc72fa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesTable_ea4592f0-821a-4a35-9322-351082aa4087" xlink:to="loc_us-gaap_FinancialInstrumentAxis_2de2003e-fe4f-4931-b70f-f5b177cc72fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_2de2003e-fe4f-4931-b70f-f5b177cc72fa" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesMember_43b0d4bb-1f2d-4ae0-9a50-e9d26fadce33" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:to="loc_us-gaap_EquitySecuritiesMember_43b0d4bb-1f2d-4ae0-9a50-e9d26fadce33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryAndGovernmentMember_83ca5b44-f24e-43b0-9eed-92c21b564ca4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USTreasuryAndGovernmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:to="loc_us-gaap_USTreasuryAndGovernmentMember_83ca5b44-f24e-43b0-9eed-92c21b564ca4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_2904b792-9a2c-4c06-aa8f-673c45991f9f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_2904b792-9a2c-4c06-aa8f-673c45991f9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_3908c455-8e85-4c53-a931-b19c39c6d8be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CorporateDebtSecuritiesMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_3908c455-8e85-4c53-a931-b19c39c6d8be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AssetbackedSecuritiesStudentLoansMember_0b1e8c02-ea0f-4f5b-a4af-a08f9be6227e" xlink:href="ntb-20201231.xsd#ntb_AssetbackedSecuritiesStudentLoansMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:to="loc_ntb_AssetbackedSecuritiesStudentLoansMember_0b1e8c02-ea0f-4f5b-a4af-a08f9be6227e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialMortgageBackedSecuritiesMember_342e4116-26ca-4326-9ad1-47fffec337e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialMortgageBackedSecuritiesMember"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:to="loc_us-gaap_CommercialMortgageBackedSecuritiesMember_342e4116-26ca-4326-9ad1-47fffec337e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_fb212ee8-fecd-486e-8cfa-5bbeeba05943" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_18c768e4-05c4-4143-a1ff-7d7c22248980" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_fb212ee8-fecd-486e-8cfa-5bbeeba05943" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_bae31a41-e8f2-45e6-ab35-e096b58132a8" xlink:href="ntb-20201231.xsd#ntb_ScheduleOfMarketableSecuritiesLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesTable_ea4592f0-821a-4a35-9322-351082aa4087" xlink:to="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_bae31a41-e8f2-45e6-ab35-e096b58132a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_bae31a41-e8f2-45e6-ab35-e096b58132a8" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AvailableForSaleSecuritiesDebtMaturitiesWithinThreeMonthsFairValue_4e329c3c-c49f-4743-968c-24224b079b72" xlink:href="ntb-20201231.xsd#ntb_AvailableForSaleSecuritiesDebtMaturitiesWithinThreeMonthsFairValue"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:to="loc_ntb_AvailableForSaleSecuritiesDebtMaturitiesWithinThreeMonthsFairValue_4e329c3c-c49f-4743-968c-24224b079b72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AvailableForSaleSecuritiesDebtMaturitiesThreeThroughTwelveMonthsFairValue_71b0f2e5-9fba-4b0d-8a20-8819b225941d" xlink:href="ntb-20201231.xsd#ntb_AvailableForSaleSecuritiesDebtMaturitiesThreeThroughTwelveMonthsFairValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:to="loc_ntb_AvailableForSaleSecuritiesDebtMaturitiesThreeThroughTwelveMonthsFairValue_71b0f2e5-9fba-4b0d-8a20-8819b225941d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_2bbe86d2-6d4a-4d14-8f97-b3866bf71266" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_2bbe86d2-6d4a-4d14-8f97-b3866bf71266" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_1fd37337-5540-4c68-a951-7a6943d61715" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_1fd37337-5540-4c68-a951-7a6943d61715" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue_5fe5d087-c77b-432f-98c2-e926a8ce2a26" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue_5fe5d087-c77b-432f-98c2-e926a8ce2a26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_e12debe3-5c1b-44f3-9888-f7a6e89967da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_e12debe3-5c1b-44f3-9888-f7a6e89967da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_984fe1f1-5083-4893-8b3a-9ff9643e2367" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAbstract_b4384b20-46f6-40d4-af9e-001230c290b4" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_984fe1f1-5083-4893-8b3a-9ff9643e2367" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_ScheduleOfMarketableSecuritiesLineItems_bae31a41-e8f2-45e6-ab35-e096b58132a8" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_HeldtomaturitySecuritiesDebtMaturitiesWithinThreeMonthsFairValue_14553694-0158-453f-98ea-6a615ea75782" xlink:href="ntb-20201231.xsd#ntb_HeldtomaturitySecuritiesDebtMaturitiesWithinThreeMonthsFairValue"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:to="loc_ntb_HeldtomaturitySecuritiesDebtMaturitiesWithinThreeMonthsFairValue_14553694-0158-453f-98ea-6a615ea75782" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_HeldtomaturitySecuritiesDebtMaturitiesThreeThroughTwelveMonthsFairValue_101ab9d7-8f3f-4cbb-a721-81d6335d230b" xlink:href="ntb-20201231.xsd#ntb_HeldtomaturitySecuritiesDebtMaturitiesThreeThroughTwelveMonthsFairValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:to="loc_ntb_HeldtomaturitySecuritiesDebtMaturitiesThreeThroughTwelveMonthsFairValue_101ab9d7-8f3f-4cbb-a721-81d6335d230b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_3b8bda04-a171-415c-b7f6-a54a710c211e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_3b8bda04-a171-415c-b7f6-a54a710c211e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_c88d0c6c-a1be-4593-81d6-20d2b67dbdfd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_c88d0c6c-a1be-4593-81d6-20d2b67dbdfd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsFairValue_4fb71ca5-bea5-4e28-ac3b-9ff229bc0eba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsFairValue"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsFairValue_4fb71ca5-bea5-4e28-ac3b-9ff229bc0eba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_9f8234af-8869-465b-afb1-d411eeaa3918" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_9f8234af-8869-465b-afb1-d411eeaa3918" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_55faac04-354b-49f9-a10c-7d887332ef2c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAbstract_e45401a4-4de0-441b-b70c-d2218ae84c26" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_55faac04-354b-49f9-a10c-7d887332ef2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesPledgedInvestmentsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#InvestmentinsecuritiesPledgedInvestmentsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesPledgedInvestmentsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_23405996-0093-4027-b8ef-3c647e094949" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesAvailableForSaleOrHeldForInvestment_6d77a559-04e0-42bc-834e-ed97737288e4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesAvailableForSaleOrHeldForInvestment"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_23405996-0093-4027-b8ef-3c647e094949" xlink:to="loc_us-gaap_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesAvailableForSaleOrHeldForInvestment_6d77a559-04e0-42bc-834e-ed97737288e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesAvailableForSaleorHeldForInvestmentFairValue_b56b68c9-7496-4ab7-8391-38f2a4c00ccf" xlink:href="ntb-20201231.xsd#ntb_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesAvailableForSaleorHeldForInvestmentFairValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_23405996-0093-4027-b8ef-3c647e094949" xlink:to="loc_ntb_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesAvailableForSaleorHeldForInvestmentFairValue_b56b68c9-7496-4ab7-8391-38f2a4c00ccf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesHeldToMaturity_d5119fa6-d13f-4ed9-b2fa-ba62a1f0f55b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesHeldToMaturity"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_23405996-0093-4027-b8ef-3c647e094949" xlink:to="loc_us-gaap_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesHeldToMaturity_d5119fa6-d13f-4ed9-b2fa-ba62a1f0f55b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesHeldToMaturityFairValue_301bd4ca-4988-439e-ac50-069f223db922" xlink:href="ntb-20201231.xsd#ntb_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesHeldToMaturityFairValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_23405996-0093-4027-b8ef-3c647e094949" xlink:to="loc_ntb_PledgedFinancialInstrumentsNotSeparatelyReportedOtherDebtSecuritiesHeldToMaturityFairValue_301bd4ca-4988-439e-ac50-069f223db922" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesSaleProceedsandRealizedGainsandLossesofAFSSecuritiesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#InvestmentinsecuritiesSaleProceedsandRealizedGainsandLossesofAFSSecuritiesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InvestmentinsecuritiesSaleProceedsandRealizedGainsandLossesofAFSSecuritiesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_3170adeb-324c-421d-9114-488b473ac454" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_347e234d-baf6-4700-b06f-aee2550e1274" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_3170adeb-324c-421d-9114-488b473ac454" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_347e234d-baf6-4700-b06f-aee2550e1274" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_8e22436e-3e90-48d9-8b2e-1be791980457" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_347e234d-baf6-4700-b06f-aee2550e1274" xlink:to="loc_us-gaap_FinancialInstrumentAxis_8e22436e-3e90-48d9-8b2e-1be791980457" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_bf864b98-ae19-46ec-ac09-2aafc8130917" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_8e22436e-3e90-48d9-8b2e-1be791980457" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_bf864b98-ae19-46ec-ac09-2aafc8130917" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryAndGovernmentMember_de4707de-95a2-4f51-9505-8bd06ea4e353" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USTreasuryAndGovernmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_bf864b98-ae19-46ec-ac09-2aafc8130917" xlink:to="loc_us-gaap_USTreasuryAndGovernmentMember_de4707de-95a2-4f51-9505-8bd06ea4e353" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_db7123f2-895e-4ed5-9984-26147105fe9b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_bf864b98-ae19-46ec-ac09-2aafc8130917" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_db7123f2-895e-4ed5-9984-26147105fe9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_ee6c5f5b-bf7b-4888-abf6-c84571f5630d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CorporateDebtSecuritiesMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_bf864b98-ae19-46ec-ac09-2aafc8130917" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_ee6c5f5b-bf7b-4888-abf6-c84571f5630d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialMortgageBackedSecuritiesMember_12aa8a46-16d2-43f7-a7f2-0b234add5d56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialMortgageBackedSecuritiesMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_bf864b98-ae19-46ec-ac09-2aafc8130917" xlink:to="loc_us-gaap_CommercialMortgageBackedSecuritiesMember_12aa8a46-16d2-43f7-a7f2-0b234add5d56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollateralizedDebtObligationsMember_007c93c6-abac-46e0-bb76-63535c2e5d49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CollateralizedDebtObligationsMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_bf864b98-ae19-46ec-ac09-2aafc8130917" xlink:to="loc_us-gaap_CollateralizedDebtObligationsMember_007c93c6-abac-46e0-bb76-63535c2e5d49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_d9c62192-b583-47d7-8a7b-1aad1d475680" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_347e234d-baf6-4700-b06f-aee2550e1274" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_d9c62192-b583-47d7-8a7b-1aad1d475680" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_5673ebeb-d22e-42dd-8e61-bf4dfd51e572" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_d9c62192-b583-47d7-8a7b-1aad1d475680" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_5673ebeb-d22e-42dd-8e61-bf4dfd51e572" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain_c2ca7579-22ec-4da3-9410-c3991406ebb1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGain"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_d9c62192-b583-47d7-8a7b-1aad1d475680" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGain_c2ca7579-22ec-4da3-9410-c3991406ebb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss_cf64b222-99df-411c-a44c-c4ed189d611a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_d9c62192-b583-47d7-8a7b-1aad1d475680" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedLoss_cf64b222-99df-411c-a44c-c4ed189d611a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Loans" xlink:type="simple" xlink:href="ntb-20201231.xsd#Loans"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Loans" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_074ce96e-d69e-4bbb-ada7-1fb26994f3b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablesTextBlock_547d68e9-f9ea-4f6b-bfc6-686aa1383816" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablesTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_074ce96e-d69e-4bbb-ada7-1fb26994f3b7" xlink:to="loc_us-gaap_FinancingReceivablesTextBlock_547d68e9-f9ea-4f6b-bfc6-686aa1383816" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoansTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoansTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoansTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_a74d0c7c-086f-4870-b953-8d6935814f22" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock_008f35cf-5994-4d19-a95f-671afefb0d8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_a74d0c7c-086f-4870-b953-8d6935814f22" xlink:to="loc_us-gaap_FinancingReceivableCreditQualityIndicatorsTableTextBlock_008f35cf-5994-4d19-a95f-671afefb0d8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PastDueFinancingReceivablesTableTextBlock_86834eb3-63f3-49da-b8db-8282c4a7d509" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PastDueFinancingReceivablesTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_a74d0c7c-086f-4870-b953-8d6935814f22" xlink:to="loc_us-gaap_PastDueFinancingReceivablesTableTextBlock_86834eb3-63f3-49da-b8db-8282c4a7d509" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForCreditLossesOnFinancingReceivablesTableTextBlock_ccc28d1d-f6d7-45df-aa02-98d356c09a95" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllowanceForCreditLossesOnFinancingReceivablesTableTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_a74d0c7c-086f-4870-b953-8d6935814f22" xlink:to="loc_us-gaap_AllowanceForCreditLossesOnFinancingReceivablesTableTextBlock_ccc28d1d-f6d7-45df-aa02-98d356c09a95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock_6dcc04ed-54d5-4f9d-92ec-e7bbec94c9bc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_a74d0c7c-086f-4870-b953-8d6935814f22" xlink:to="loc_us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock_6dcc04ed-54d5-4f9d-92ec-e7bbec94c9bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock_7b85c5a5-9a12-48ab-b097-7904f78d0b83" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_a74d0c7c-086f-4870-b953-8d6935814f22" xlink:to="loc_us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock_7b85c5a5-9a12-48ab-b097-7904f78d0b83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoansAdditionalInformationDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoansAdditionalInformationDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoansAdditionalInformationDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_8d16fea5-60be-4195-8faf-bb3cfadff3be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivableWithImputedInterestEffectiveYieldInterestRate_40c285a9-b2c2-4343-bc6b-46a7c19a474c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivableWithImputedInterestEffectiveYieldInterestRate"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_8d16fea5-60be-4195-8faf-bb3cfadff3be" xlink:to="loc_us-gaap_ReceivableWithImputedInterestEffectiveYieldInterestRate_40c285a9-b2c2-4343-bc6b-46a7c19a474c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestReceivable_6c990a87-8fc6-4493-bcfb-cadb36418418" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestReceivable"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_8d16fea5-60be-4195-8faf-bb3cfadff3be" xlink:to="loc_us-gaap_InterestReceivable_6c990a87-8fc6-4493-bcfb-cadb36418418" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoansLoansCreditQualityDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoansLoansCreditQualityDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoansLoansCreditQualityDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_5f6f4390-d851-430e-a723-52559e752696" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_5f6f4390-d851-430e-a723-52559e752696" xlink:to="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InternalCreditAssessmentAxis_3948a6b8-f555-4310-a7a1-5ea2fb21d7e5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InternalCreditAssessmentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:to="loc_us-gaap_InternalCreditAssessmentAxis_3948a6b8-f555-4310-a7a1-5ea2fb21d7e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InternalCreditAssessmentDomain_6e3abf5f-5269-4fb9-a363-100a41f85eae" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InternalCreditAssessmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InternalCreditAssessmentAxis_3948a6b8-f555-4310-a7a1-5ea2fb21d7e5" xlink:to="loc_us-gaap_InternalCreditAssessmentDomain_6e3abf5f-5269-4fb9-a363-100a41f85eae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PassMember_769aa461-3832-4a66-95b1-ae0830e21dac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PassMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InternalCreditAssessmentDomain_6e3abf5f-5269-4fb9-a363-100a41f85eae" xlink:to="loc_us-gaap_PassMember_769aa461-3832-4a66-95b1-ae0830e21dac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SpecialMentionMember_f6589f8e-1d26-4576-8a55-43b49e90fdbe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SpecialMentionMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InternalCreditAssessmentDomain_6e3abf5f-5269-4fb9-a363-100a41f85eae" xlink:to="loc_us-gaap_SpecialMentionMember_f6589f8e-1d26-4576-8a55-43b49e90fdbe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubstandardMember_148a4b02-91a9-4c33-ace6-a010f18177f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubstandardMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InternalCreditAssessmentDomain_6e3abf5f-5269-4fb9-a363-100a41f85eae" xlink:to="loc_us-gaap_SubstandardMember_148a4b02-91a9-4c33-ace6-a010f18177f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DoubtfulMember_89c771e0-ba8b-4de5-8f71-38a88bb5fed1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DoubtfulMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InternalCreditAssessmentDomain_6e3abf5f-5269-4fb9-a363-100a41f85eae" xlink:to="loc_us-gaap_DoubtfulMember_89c771e0-ba8b-4de5-8f71-38a88bb5fed1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_76278607-fe51-4e47-8d11-c51b13ca21ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_76278607-fe51-4e47-8d11-c51b13ca21ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_f6106263-0695-4f9d-b51f-9453c7f4cfc8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_76278607-fe51-4e47-8d11-c51b13ca21ef" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_f6106263-0695-4f9d-b51f-9453c7f4cfc8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPortfolioSegmentMember_196b7c80-8d97-4332-bada-2e930bc0c46f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialPortfolioSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_f6106263-0695-4f9d-b51f-9453c7f4cfc8" xlink:to="loc_us-gaap_CommercialPortfolioSegmentMember_196b7c80-8d97-4332-bada-2e930bc0c46f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_894735d6-c991-443e-ad02-0f024e272659" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialRealEstatePortfolioSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_f6106263-0695-4f9d-b51f-9453c7f4cfc8" xlink:to="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_894735d6-c991-443e-ad02-0f024e272659" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsumerPortfolioSegmentMember_8de2bec7-facd-425c-81c7-b4ff2427de93" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsumerPortfolioSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_f6106263-0695-4f9d-b51f-9453c7f4cfc8" xlink:to="loc_us-gaap_ConsumerPortfolioSegmentMember_8de2bec7-facd-425c-81c7-b4ff2427de93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialPortfolioSegmentMember_fa0535c5-46a5-4cb8-bc3b-ee890b24f136" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialPortfolioSegmentMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_f6106263-0695-4f9d-b51f-9453c7f4cfc8" xlink:to="loc_us-gaap_ResidentialPortfolioSegmentMember_fa0535c5-46a5-4cb8-bc3b-ee890b24f136" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesByIndustryAxis_6b01f26a-88ba-44bf-b911-b3213b25f759" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesByIndustryAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:to="loc_us-gaap_EquitySecuritiesByIndustryAxis_6b01f26a-88ba-44bf-b911-b3213b25f759" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesIndustryMember_77154b77-4e47-470f-a5d6-f2aaf105bce1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesIndustryMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesByIndustryAxis_6b01f26a-88ba-44bf-b911-b3213b25f759" xlink:to="loc_us-gaap_EquitySecuritiesIndustryMember_77154b77-4e47-470f-a5d6-f2aaf105bce1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GovernmentSectorMember_3553350b-c651-40b8-bb23-f4c6d83f997c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GovernmentSectorMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesIndustryMember_77154b77-4e47-470f-a5d6-f2aaf105bce1" xlink:to="loc_us-gaap_GovernmentSectorMember_3553350b-c651-40b8-bb23-f4c6d83f997c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialAndIndustrialSectorMember_08582945-556d-4d02-8f9d-24ad248ae9c4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialAndIndustrialSectorMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesIndustryMember_77154b77-4e47-470f-a5d6-f2aaf105bce1" xlink:to="loc_us-gaap_CommercialAndIndustrialSectorMember_08582945-556d-4d02-8f9d-24ad248ae9c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_c507fd6b-95fb-41d2-a0a6-604824a49b92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_c507fd6b-95fb-41d2-a0a6-604824a49b92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_c507fd6b-95fb-41d2-a0a6-604824a49b92" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OverdraftLoanMember_e24f8cb3-3c7f-4594-a6b6-0d091736a90a" xlink:href="ntb-20201231.xsd#ntb_OverdraftLoanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:to="loc_ntb_OverdraftLoanMember_e24f8cb3-3c7f-4594-a6b6-0d091736a90a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealEstateLoanMember_26bcdae5-5798-4685-a8d3-be64906bbc40" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RealEstateLoanMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:to="loc_us-gaap_RealEstateLoanMember_26bcdae5-5798-4685-a8d3-be64906bbc40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionLoansMember_4145ab7c-05d8-4191-9a8e-4146ce0277d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConstructionLoansMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:to="loc_us-gaap_ConstructionLoansMember_4145ab7c-05d8-4191-9a8e-4146ce0277d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AutomobileLoanMember_403cacf7-2fc0-4d67-8b19-f50e27bfd20f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AutomobileLoanMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:to="loc_us-gaap_AutomobileLoanMember_403cacf7-2fc0-4d67-8b19-f50e27bfd20f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditCardReceivablesMember_db573f43-2702-4b18-aefe-5394ec0b8137" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditCardReceivablesMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:to="loc_us-gaap_CreditCardReceivablesMember_db573f43-2702-4b18-aefe-5394ec0b8137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherLoansMember_1a10cd25-1009-467b-bc98-b4f857a28344" xlink:href="ntb-20201231.xsd#ntb_OtherLoansMember"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_c73e37d9-5e3e-4f01-a9e0-21ab886fb6b0" xlink:to="loc_ntb_OtherLoansMember_1a10cd25-1009-467b-bc98-b4f857a28344" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollateralAxis_c5e78e6b-8e09-4336-9e13-52950d5a60d0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CollateralAxis"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:to="loc_us-gaap_CollateralAxis_c5e78e6b-8e09-4336-9e13-52950d5a60d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollateralDomain_64b9ac47-72cd-4dac-9964-d9bd3e6291e2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CollateralDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollateralAxis_c5e78e6b-8e09-4336-9e13-52950d5a60d0" xlink:to="loc_us-gaap_CollateralDomain_64b9ac47-72cd-4dac-9964-d9bd3e6291e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CashAndPortfolioSecuredLendingCollateralMember_208d656c-4da7-452b-a512-b4e293dbf130" xlink:href="ntb-20201231.xsd#ntb_CashAndPortfolioSecuredLendingCollateralMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollateralDomain_64b9ac47-72cd-4dac-9964-d9bd3e6291e2" xlink:to="loc_ntb_CashAndPortfolioSecuredLendingCollateralMember_208d656c-4da7-452b-a512-b4e293dbf130" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BuildingsInConstructionOrOtherCollateralMember_d42c639f-4f93-4869-8daa-2a06d9c8bc2d" xlink:href="ntb-20201231.xsd#ntb_BuildingsInConstructionOrOtherCollateralMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollateralDomain_64b9ac47-72cd-4dac-9964-d9bd3e6291e2" xlink:to="loc_ntb_BuildingsInConstructionOrOtherCollateralMember_d42c639f-4f93-4869-8daa-2a06d9c8bc2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentLineItems"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable_6f802203-d7d0-4c8d-9b67-a33f4c07137d" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross_1bc433c7-dc74-456d-a658-afd7cb43a04d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableGross"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_NotesReceivableGross_1bc433c7-dc74-456d-a658-afd7cb43a04d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_3f70f3db-fe65-461f-869e-959c8e64f9bb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLosses"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_3f70f3db-fe65-461f-869e-959c8e64f9bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableNet_b309aae5-2046-4ae3-b385-9044aaa2d831" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableNet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_NotesReceivableNet_b309aae5-2046-4ae3-b385-9044aaa2d831" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract_16ed4530-6e9d-4095-9638-f9901a6f96d8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract_16ed4530-6e9d-4095-9638-f9901a6f96d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment_c89f4132-c56e-436a-905c-e48f8385def3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract_16ed4530-6e9d-4095-9638-f9901a6f96d8" xlink:to="loc_us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment_c89f4132-c56e-436a-905c-e48f8385def3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment_43ced5bf-60ab-4398-9091-59c1f8efb991" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract_16ed4530-6e9d-4095-9638-f9901a6f96d8" xlink:to="loc_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment_43ced5bf-60ab-4398-9091-59c1f8efb991" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableOriginatedInCurrentFiscalYear_8add2de1-306b-4c9f-ba05-7753f5ae4347" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableOriginatedInCurrentFiscalYear"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableOriginatedInCurrentFiscalYear_8add2de1-306b-4c9f-ba05-7753f5ae4347" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableOriginatedInFiscalYearBeforeLatestFiscalYear_88947ac3-3913-4392-bff1-16763ea66b56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableOriginatedInFiscalYearBeforeLatestFiscalYear"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableOriginatedInFiscalYearBeforeLatestFiscalYear_88947ac3-3913-4392-bff1-16763ea66b56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableOriginatedTwoYearsBeforeLatestFiscalYear_8bddb4a8-2747-4a10-9e59-daedaebaaab5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableOriginatedTwoYearsBeforeLatestFiscalYear"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableOriginatedTwoYearsBeforeLatestFiscalYear_8bddb4a8-2747-4a10-9e59-daedaebaaab5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableOriginatedThreeYearsBeforeLatestFiscalYear_aae271e6-40cb-4747-9650-32b8bf274d01" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableOriginatedThreeYearsBeforeLatestFiscalYear"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableOriginatedThreeYearsBeforeLatestFiscalYear_aae271e6-40cb-4747-9650-32b8bf274d01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableOriginatedFourYearsBeforeLatestFiscalYear_3996b34f-93fb-43b0-b6b7-8f418ac44048" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableOriginatedFourYearsBeforeLatestFiscalYear"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableOriginatedFourYearsBeforeLatestFiscalYear_3996b34f-93fb-43b0-b6b7-8f418ac44048" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_fc643783-97c6-45c4-8a51-c4147b9d6408" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableOriginatedFiveOrMoreYearsBeforeLatestFiscalYear"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableOriginatedFiveOrMoreYearsBeforeLatestFiscalYear_fc643783-97c6-45c4-8a51-c4147b9d6408" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRevolving_e3ccbf5c-5966-4142-b514-40ad5ae05eed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRevolving"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentLineItems_c511002b-9fad-4834-a649-afaf8eb2fbb2" xlink:to="loc_us-gaap_FinancingReceivableRevolving_e3ccbf5c-5966-4142-b514-40ad5ae05eed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoansAgeAnalysisofPastDueLoansIncludingNonAccrualLoansDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoansAgeAnalysisofPastDueLoansIncludingNonAccrualLoansDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoansAgeAnalysisofPastDueLoansIncludingNonAccrualLoansDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_f3d5327c-c2cd-4e4f-a942-f2e17cc5fb67" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_b2a773a6-aba0-4fa0-bd4b-e51cb9b64af2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFinancingReceivablesPastDueTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_f3d5327c-c2cd-4e4f-a942-f2e17cc5fb67" xlink:to="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_b2a773a6-aba0-4fa0-bd4b-e51cb9b64af2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_50040742-8bc8-4562-bb04-ea9af5232751" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_b2a773a6-aba0-4fa0-bd4b-e51cb9b64af2" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_50040742-8bc8-4562-bb04-ea9af5232751" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_8078b293-f117-4e1d-a814-d1c286073a66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_50040742-8bc8-4562-bb04-ea9af5232751" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_8078b293-f117-4e1d-a814-d1c286073a66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPortfolioSegmentMember_24890b98-04db-47fd-9e28-9c1938ef38a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialPortfolioSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_8078b293-f117-4e1d-a814-d1c286073a66" xlink:to="loc_us-gaap_CommercialPortfolioSegmentMember_24890b98-04db-47fd-9e28-9c1938ef38a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_446b3830-16b1-4080-9ae0-096589c729df" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialRealEstatePortfolioSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_8078b293-f117-4e1d-a814-d1c286073a66" xlink:to="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_446b3830-16b1-4080-9ae0-096589c729df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsumerPortfolioSegmentMember_457aca3d-5e08-436b-ae31-d007edaa6139" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsumerPortfolioSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_8078b293-f117-4e1d-a814-d1c286073a66" xlink:to="loc_us-gaap_ConsumerPortfolioSegmentMember_457aca3d-5e08-436b-ae31-d007edaa6139" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialPortfolioSegmentMember_047145ff-3779-426b-b1f6-72fe21982f46" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialPortfolioSegmentMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_8078b293-f117-4e1d-a814-d1c286073a66" xlink:to="loc_us-gaap_ResidentialPortfolioSegmentMember_047145ff-3779-426b-b1f6-72fe21982f46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesByIndustryAxis_6ff0e41b-2fb0-4696-9288-69303cd0ee3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesByIndustryAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_b2a773a6-aba0-4fa0-bd4b-e51cb9b64af2" xlink:to="loc_us-gaap_EquitySecuritiesByIndustryAxis_6ff0e41b-2fb0-4696-9288-69303cd0ee3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesIndustryMember_eca48e69-2f0f-47f0-9a23-35ae8fc9a6bd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesIndustryMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesByIndustryAxis_6ff0e41b-2fb0-4696-9288-69303cd0ee3c" xlink:to="loc_us-gaap_EquitySecuritiesIndustryMember_eca48e69-2f0f-47f0-9a23-35ae8fc9a6bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GovernmentSectorMember_936047c0-d6f2-4178-bae1-8430e9600a31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GovernmentSectorMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesIndustryMember_eca48e69-2f0f-47f0-9a23-35ae8fc9a6bd" xlink:to="loc_us-gaap_GovernmentSectorMember_936047c0-d6f2-4178-bae1-8430e9600a31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialAndIndustrialSectorMember_ea3a4cf3-699f-4f11-a92e-95cbfb9f67c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialAndIndustrialSectorMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesIndustryMember_eca48e69-2f0f-47f0-9a23-35ae8fc9a6bd" xlink:to="loc_us-gaap_CommercialAndIndustrialSectorMember_ea3a4cf3-699f-4f11-a92e-95cbfb9f67c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_c10dcc5a-e3eb-462f-810b-589994249ea5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_b2a773a6-aba0-4fa0-bd4b-e51cb9b64af2" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_c10dcc5a-e3eb-462f-810b-589994249ea5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_c10dcc5a-e3eb-462f-810b-589994249ea5" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OverdraftLoanMember_37d4025d-f6bf-48f9-8331-16d5fd11ce44" xlink:href="ntb-20201231.xsd#ntb_OverdraftLoanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:to="loc_ntb_OverdraftLoanMember_37d4025d-f6bf-48f9-8331-16d5fd11ce44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealEstateLoanMember_d5694c5d-352b-465a-bde5-e5c4b5140eef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RealEstateLoanMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:to="loc_us-gaap_RealEstateLoanMember_d5694c5d-352b-465a-bde5-e5c4b5140eef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionLoansMember_1a7ab30d-b827-4920-a40b-781123902cad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConstructionLoansMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:to="loc_us-gaap_ConstructionLoansMember_1a7ab30d-b827-4920-a40b-781123902cad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AutomobileLoanMember_282f76f6-e548-40c5-af17-5ce9995aac31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AutomobileLoanMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:to="loc_us-gaap_AutomobileLoanMember_282f76f6-e548-40c5-af17-5ce9995aac31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditCardReceivablesMember_e90dc244-9765-408a-9c59-c9499a5a5df0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditCardReceivablesMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:to="loc_us-gaap_CreditCardReceivablesMember_e90dc244-9765-408a-9c59-c9499a5a5df0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherLoansMember_3ebaff94-bcec-4387-86dc-5896d2689e81" xlink:href="ntb-20201231.xsd#ntb_OtherLoansMember"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_f27d79f8-a19a-43eb-a210-ae29b9be61a8" xlink:to="loc_ntb_OtherLoansMember_3ebaff94-bcec-4387-86dc-5896d2689e81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablesPeriodPastDueAxis_f5cf4f47-928b-4f84-8260-8f2bb438b5f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablesPeriodPastDueAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_b2a773a6-aba0-4fa0-bd4b-e51cb9b64af2" xlink:to="loc_us-gaap_FinancingReceivablesPeriodPastDueAxis_f5cf4f47-928b-4f84-8260-8f2bb438b5f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablesPeriodPastDueDomain_1e17d155-be4e-413b-9457-e3e9984edcb4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablesPeriodPastDueDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablesPeriodPastDueAxis_f5cf4f47-928b-4f84-8260-8f2bb438b5f0" xlink:to="loc_us-gaap_FinancingReceivablesPeriodPastDueDomain_1e17d155-be4e-413b-9457-e3e9984edcb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivables30To59DaysPastDueMember_9ad52bb0-a4c0-4550-ad28-ad4961a6f19e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivables30To59DaysPastDueMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablesPeriodPastDueDomain_1e17d155-be4e-413b-9457-e3e9984edcb4" xlink:to="loc_us-gaap_FinancingReceivables30To59DaysPastDueMember_9ad52bb0-a4c0-4550-ad28-ad4961a6f19e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivables60To89DaysPastDueMember_9fca8136-797d-4c3a-b52a-de31902ad825" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivables60To89DaysPastDueMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablesPeriodPastDueDomain_1e17d155-be4e-413b-9457-e3e9984edcb4" xlink:to="loc_us-gaap_FinancingReceivables60To89DaysPastDueMember_9fca8136-797d-4c3a-b52a-de31902ad825" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember_165c922b-5fed-4937-9455-457c419421de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablesPeriodPastDueDomain_1e17d155-be4e-413b-9457-e3e9984edcb4" xlink:to="loc_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember_165c922b-5fed-4937-9455-457c419421de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_f25a8f3a-2192-4973-9586-f61803d28f69" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_b2a773a6-aba0-4fa0-bd4b-e51cb9b64af2" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_f25a8f3a-2192-4973-9586-f61803d28f69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDue_524bdc08-9cec-4d49-9d2a-0f3cdf439717" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentPastDue"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_f25a8f3a-2192-4973-9586-f61803d28f69" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDue_524bdc08-9cec-4d49-9d2a-0f3cdf439717" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentCurrent_ff69b8a2-29c3-4415-af05-b5cc367a4060" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentCurrent"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_f25a8f3a-2192-4973-9586-f61803d28f69" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentCurrent_ff69b8a2-29c3-4415-af05-b5cc367a4060" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross_09c8185a-684a-4f28-83db-8791faf67d69" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableGross"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_f25a8f3a-2192-4973-9586-f61803d28f69" xlink:to="loc_us-gaap_NotesReceivableGross_09c8185a-684a-4f28-83db-8791faf67d69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoansChangesinAllowancesforCreditLossesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoansChangesinAllowancesforCreditLossesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoansChangesinAllowancesforCreditLossesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_27ff49e7-c0d9-4c0c-80ca-22dfd0e73e65" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable_950b1316-9378-42d1-a9b9-2226fb6dbd66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_27ff49e7-c0d9-4c0c-80ca-22dfd0e73e65" xlink:to="loc_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable_950b1316-9378-42d1-a9b9-2226fb6dbd66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_b3340a5c-7d39-483b-ba06-b560d7ceb1e0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable_950b1316-9378-42d1-a9b9-2226fb6dbd66" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_b3340a5c-7d39-483b-ba06-b560d7ceb1e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_7bc0d1f7-47c7-4dc6-b328-d473f0f03884" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_b3340a5c-7d39-483b-ba06-b560d7ceb1e0" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_7bc0d1f7-47c7-4dc6-b328-d473f0f03884" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPortfolioSegmentMember_3ddd4584-ff7c-4e5e-85cf-fa65d0c34b53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialPortfolioSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_7bc0d1f7-47c7-4dc6-b328-d473f0f03884" xlink:to="loc_us-gaap_CommercialPortfolioSegmentMember_3ddd4584-ff7c-4e5e-85cf-fa65d0c34b53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_0c7cd3f2-05bc-4de6-89cb-2dabbcfabadb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialRealEstatePortfolioSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_7bc0d1f7-47c7-4dc6-b328-d473f0f03884" xlink:to="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_0c7cd3f2-05bc-4de6-89cb-2dabbcfabadb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsumerPortfolioSegmentMember_2b2884b7-f3c8-4bf3-b552-22bf2614b9a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsumerPortfolioSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_7bc0d1f7-47c7-4dc6-b328-d473f0f03884" xlink:to="loc_us-gaap_ConsumerPortfolioSegmentMember_2b2884b7-f3c8-4bf3-b552-22bf2614b9a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialPortfolioSegmentMember_6050a7f7-d496-4e94-a58b-c577aceb7b84" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialPortfolioSegmentMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_7bc0d1f7-47c7-4dc6-b328-d473f0f03884" xlink:to="loc_us-gaap_ResidentialPortfolioSegmentMember_6050a7f7-d496-4e94-a58b-c577aceb7b84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_5dcc2461-72c2-483c-b7cf-cd539de18e76" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable_950b1316-9378-42d1-a9b9-2226fb6dbd66" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_5dcc2461-72c2-483c-b7cf-cd539de18e76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_9b3b0e4f-9170-4ffb-befe-04c761d66323" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_5dcc2461-72c2-483c-b7cf-cd539de18e76" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_9b3b0e4f-9170-4ffb-befe-04c761d66323" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_491f1344-812c-42d9-bf61-46134e37dfd4" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_9b3b0e4f-9170-4ffb-befe-04c761d66323" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_491f1344-812c-42d9-bf61-46134e37dfd4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems_92d05909-b601-48e3-aa3f-b63fe1bde291" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable_950b1316-9378-42d1-a9b9-2226fb6dbd66" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems_92d05909-b601-48e3-aa3f-b63fe1bde291" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems_92d05909-b601-48e3-aa3f-b63fe1bde291" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_7b12c630-8f45-40fe-ac6e-b34cda80f61b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLosses"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_7b12c630-8f45-40fe-ac6e-b34cda80f61b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_f0b89a1f-6b5f-48ff-b920-3c4589bad437" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForLoanLeaseAndOtherLosses"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:to="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_f0b89a1f-6b5f-48ff-b920-3c4589bad437" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRecovery_1a7151c5-0176-4534-ad66-67cfff280774" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesRecovery"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRecovery_1a7151c5-0176-4534-ad66-67cfff280774" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs_708e4354-7a36-4d6f-a1d8-c02e4b0740ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs_708e4354-7a36-4d6f-a1d8-c02e4b0740ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FinancingReceivableAllowanceForCreditLossesOther_a2684908-559d-4a82-801a-d39285e43c73" xlink:href="ntb-20201231.xsd#ntb_FinancingReceivableAllowanceForCreditLossesOther"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:to="loc_ntb_FinancingReceivableAllowanceForCreditLossesOther_a2684908-559d-4a82-801a-d39285e43c73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_e6a19366-03da-4ac3-a067-67748e117c2f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLosses"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward_5dd46a67-db90-40af-8be7-ec85fd4048bf" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_e6a19366-03da-4ac3-a067-67748e117c2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1_e9e1d357-54c4-4052-87fa-dfbf32b73128" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems_92d05909-b601-48e3-aa3f-b63fe1bde291" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1_e9e1d357-54c4-4052-87fa-dfbf32b73128" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment_be4485a3-f2c8-478d-9ed8-5ac26e8de9be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems_92d05909-b601-48e3-aa3f-b63fe1bde291" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment_be4485a3-f2c8-478d-9ed8-5ac26e8de9be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoansNonPerformingLoansDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoansNonPerformingLoansDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoansNonPerformingLoansDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_1b704ebe-0824-428c-b36e-dfb48a1a147a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFinancingReceivablesPastDueTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_1b704ebe-0824-428c-b36e-dfb48a1a147a" xlink:to="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentPerformanceStatusAxis_fc4839a3-e7d9-4f98-8f3f-077f258e9175" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentPerformanceStatusAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:to="loc_us-gaap_FinancialInstrumentPerformanceStatusAxis_fc4839a3-e7d9-4f98-8f3f-077f258e9175" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentPerformanceStatusDomain_63e32ca4-7ff6-4780-907c-e0340fc17058" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentPerformanceStatusDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentPerformanceStatusAxis_fc4839a3-e7d9-4f98-8f3f-077f258e9175" xlink:to="loc_us-gaap_FinancialInstrumentPerformanceStatusDomain_63e32ca4-7ff6-4780-907c-e0340fc17058" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonperformingFinancingReceivableMember_7ce67cb6-9156-45e0-be41-56fd497374aa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NonperformingFinancingReceivableMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentPerformanceStatusDomain_63e32ca4-7ff6-4780-907c-e0340fc17058" xlink:to="loc_us-gaap_NonperformingFinancingReceivableMember_7ce67cb6-9156-45e0-be41-56fd497374aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_1f12a8b5-7a3c-4c42-8fcf-33b54920d198" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_1f12a8b5-7a3c-4c42-8fcf-33b54920d198" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_6bb87a60-e71f-42cf-a114-c161d92438a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_1f12a8b5-7a3c-4c42-8fcf-33b54920d198" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_6bb87a60-e71f-42cf-a114-c161d92438a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPortfolioSegmentMember_6e1b69ec-7a2e-4bb1-8b80-d8611ebba4c6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialPortfolioSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_6bb87a60-e71f-42cf-a114-c161d92438a7" xlink:to="loc_us-gaap_CommercialPortfolioSegmentMember_6e1b69ec-7a2e-4bb1-8b80-d8611ebba4c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_e474ce9b-5154-465e-9195-2fcdf56a318b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialRealEstatePortfolioSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_6bb87a60-e71f-42cf-a114-c161d92438a7" xlink:to="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_e474ce9b-5154-465e-9195-2fcdf56a318b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsumerPortfolioSegmentMember_9fc35859-22b2-4645-8c56-633bf6fdc6fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsumerPortfolioSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_6bb87a60-e71f-42cf-a114-c161d92438a7" xlink:to="loc_us-gaap_ConsumerPortfolioSegmentMember_9fc35859-22b2-4645-8c56-633bf6fdc6fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialPortfolioSegmentMember_780fe504-2975-4e56-b111-5de2c08c8e4b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialPortfolioSegmentMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_6bb87a60-e71f-42cf-a114-c161d92438a7" xlink:to="loc_us-gaap_ResidentialPortfolioSegmentMember_780fe504-2975-4e56-b111-5de2c08c8e4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesByIndustryAxis_cf5fc599-13ef-4451-9190-e9868ddf1214" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesByIndustryAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:to="loc_us-gaap_EquitySecuritiesByIndustryAxis_cf5fc599-13ef-4451-9190-e9868ddf1214" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesIndustryMember_eb776826-d3b2-4f79-98e8-06c962ea52b1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesIndustryMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesByIndustryAxis_cf5fc599-13ef-4451-9190-e9868ddf1214" xlink:to="loc_us-gaap_EquitySecuritiesIndustryMember_eb776826-d3b2-4f79-98e8-06c962ea52b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialAndIndustrialSectorMember_f258212e-3ab5-41fa-b9b8-27b073f27b34" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialAndIndustrialSectorMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquitySecuritiesIndustryMember_eb776826-d3b2-4f79-98e8-06c962ea52b1" xlink:to="loc_us-gaap_CommercialAndIndustrialSectorMember_f258212e-3ab5-41fa-b9b8-27b073f27b34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_3b093a8e-8a5a-4f3a-ab98-082831a1bb34" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_3b093a8e-8a5a-4f3a-ab98-082831a1bb34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis_3b093a8e-8a5a-4f3a-ab98-082831a1bb34" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OverdraftLoanMember_170bda6f-7409-4b04-85b2-409b8ceb08e4" xlink:href="ntb-20201231.xsd#ntb_OverdraftLoanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:to="loc_ntb_OverdraftLoanMember_170bda6f-7409-4b04-85b2-409b8ceb08e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealEstateLoanMember_d20b7a19-1f89-4180-bc13-3ebefe25dc63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RealEstateLoanMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:to="loc_us-gaap_RealEstateLoanMember_d20b7a19-1f89-4180-bc13-3ebefe25dc63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionLoansMember_c463e680-ea16-4f9b-bb99-67750b30ad98" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConstructionLoansMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:to="loc_us-gaap_ConstructionLoansMember_c463e680-ea16-4f9b-bb99-67750b30ad98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AutomobileLoanMember_36ef9314-7ff3-4605-9823-bbf5bfe37dad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AutomobileLoanMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:to="loc_us-gaap_AutomobileLoanMember_36ef9314-7ff3-4605-9823-bbf5bfe37dad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditCardReceivablesMember_db829da3-0bb9-4afd-89cc-c5b1a84ae2e5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditCardReceivablesMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:to="loc_us-gaap_CreditCardReceivablesMember_db829da3-0bb9-4afd-89cc-c5b1a84ae2e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherLoansMember_3febd604-594b-41c1-98b4-1560b4052268" xlink:href="ntb-20201231.xsd#ntb_OtherLoansMember"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentClassOfFinancingReceivableDomain_58b6f483-bfe3-4ae4-904b-181242ee7785" xlink:to="loc_ntb_OtherLoansMember_3febd604-594b-41c1-98b4-1560b4052268" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditLossStatusAxis_5622517a-a58b-43e7-8c7d-12e6693b4020" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditLossStatusAxis"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:to="loc_us-gaap_CreditLossStatusAxis_5622517a-a58b-43e7-8c7d-12e6693b4020" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditLossStatusDomain_087df78e-66c8-46f3-b532-0a56f607ae92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditLossStatusDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditLossStatusAxis_5622517a-a58b-43e7-8c7d-12e6693b4020" xlink:to="loc_us-gaap_CreditLossStatusDomain_087df78e-66c8-46f3-b532-0a56f607ae92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialAssetAcquiredWithCreditDeteriorationMember_f3514d14-7d2f-4a39-abfa-9efb56d2ab7d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialAssetAcquiredWithCreditDeteriorationMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditLossStatusDomain_087df78e-66c8-46f3-b532-0a56f607ae92" xlink:to="loc_us-gaap_FinancialAssetAcquiredWithCreditDeteriorationMember_f3514d14-7d2f-4a39-abfa-9efb56d2ab7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_5fda4c80-a2e3-43ec-a191-2ce426ae67a0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivablesPastDueTable_f66b3270-07b3-4710-acc8-0354375fdf51" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_5fda4c80-a2e3-43ec-a191-2ce426ae67a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableNonaccrualInterestIncome_df94e573-60c6-4241-9e47-f94262f29c47" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableNonaccrualInterestIncome"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_5fda4c80-a2e3-43ec-a191-2ce426ae67a0" xlink:to="loc_us-gaap_FinancingReceivableNonaccrualInterestIncome_df94e573-60c6-4241-9e47-f94262f29c47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentNonaccrualStatus_395eceaf-6b27-42a8-9be4-33ce7ba046a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentNonaccrualStatus"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_5fda4c80-a2e3-43ec-a191-2ce426ae67a0" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentNonaccrualStatus_395eceaf-6b27-42a8-9be4-33ce7ba046a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableNonaccrualNoAllowance_9b3d0778-7c7c-4ff4-8472-0a9a6da0a964" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableNonaccrualNoAllowance"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_5fda4c80-a2e3-43ec-a191-2ce426ae67a0" xlink:to="loc_us-gaap_FinancingReceivableNonaccrualNoAllowance_9b3d0778-7c7c-4ff4-8472-0a9a6da0a964" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing_2296b983-ae9c-470c-b2a2-1e4591eea6b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_5fda4c80-a2e3-43ec-a191-2ce426ae67a0" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing_2296b983-ae9c-470c-b2a2-1e4591eea6b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross_fa528cf2-a039-414e-a9e1-01660d7e5907" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableGross"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems_5fda4c80-a2e3-43ec-a191-2ce426ae67a0" xlink:to="loc_us-gaap_NotesReceivableGross_fa528cf2-a039-414e-a9e1-01660d7e5907" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoansLoansModifiedinaTDRDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoansLoansModifiedinaTDRDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoansLoansModifiedinaTDRDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_5ff998f4-cd2c-497a-85b2-330b478ba086" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableModificationsSubsequentDefaultNumberOfContracts1_2831c2fe-b1d7-47e8-a8db-acf79df7ebc4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableModificationsSubsequentDefaultNumberOfContracts1"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_5ff998f4-cd2c-497a-85b2-330b478ba086" xlink:to="loc_us-gaap_FinancingReceivableModificationsSubsequentDefaultNumberOfContracts1_2831c2fe-b1d7-47e8-a8db-acf79df7ebc4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable_9cc7ba23-a1c6-436f-8f34-bad2ec4f578a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_5ff998f4-cd2c-497a-85b2-330b478ba086" xlink:to="loc_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable_9cc7ba23-a1c6-436f-8f34-bad2ec4f578a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_ccc14b07-74fa-4045-9ebe-77e5c6bb403a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable_9cc7ba23-a1c6-436f-8f34-bad2ec4f578a" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_ccc14b07-74fa-4045-9ebe-77e5c6bb403a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_d84d3102-6d2f-48b1-81dc-5f7dac247b63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivablePortfolioSegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentAxis_ccc14b07-74fa-4045-9ebe-77e5c6bb403a" xlink:to="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_d84d3102-6d2f-48b1-81dc-5f7dac247b63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPortfolioSegmentMember_89b64be5-891d-4f30-917c-5d12987a05af" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialPortfolioSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_d84d3102-6d2f-48b1-81dc-5f7dac247b63" xlink:to="loc_us-gaap_CommercialPortfolioSegmentMember_89b64be5-891d-4f30-917c-5d12987a05af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_9edd9584-41ac-43b8-898b-a295c0799e31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialRealEstatePortfolioSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_d84d3102-6d2f-48b1-81dc-5f7dac247b63" xlink:to="loc_us-gaap_CommercialRealEstatePortfolioSegmentMember_9edd9584-41ac-43b8-898b-a295c0799e31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialPortfolioSegmentMember_ef5fecc1-51f4-46e7-affb-129d38ba0dda" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialPortfolioSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivablePortfolioSegmentDomain_d84d3102-6d2f-48b1-81dc-5f7dac247b63" xlink:to="loc_us-gaap_ResidentialPortfolioSegmentMember_ef5fecc1-51f4-46e7-affb-129d38ba0dda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableModificationsLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable_9cc7ba23-a1c6-436f-8f34-bad2ec4f578a" xlink:to="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableModificationsNumberOfContracts2_c02274f5-6cd0-405b-bbd9-f4e15fa44119" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableModificationsNumberOfContracts2"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:to="loc_us-gaap_FinancingReceivableModificationsNumberOfContracts2_c02274f5-6cd0-405b-bbd9-f4e15fa44119" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2_e4af2873-cba7-4b4d-b598-bc529e7a7f9a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:to="loc_us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2_e4af2873-cba7-4b4d-b598-bc529e7a7f9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FinancingReceivableModificationsInterestCapitalization_c534d608-8ed5-454c-9979-22d8dba1569c" xlink:href="ntb-20201231.xsd#ntb_FinancingReceivableModificationsInterestCapitalization"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:to="loc_ntb_FinancingReceivableModificationsInterestCapitalization_c534d608-8ed5-454c-9979-22d8dba1569c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2_eea4365c-fe76-4438-8671-723b90d2aa92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:to="loc_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2_eea4365c-fe76-4438-8671-723b90d2aa92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FinancingReceivableModificationsRecordedInvestmentAccrual_d3ec5304-af64-49d7-a37a-ab58156823a4" xlink:href="ntb-20201231.xsd#ntb_FinancingReceivableModificationsRecordedInvestmentAccrual"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:to="loc_ntb_FinancingReceivableModificationsRecordedInvestmentAccrual_d3ec5304-af64-49d7-a37a-ab58156823a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FinancingReceivableModificationsRecordedInvestmentNonAccrual_e5a558ea-aec2-452a-9e35-4cb63b699c4d" xlink:href="ntb-20201231.xsd#ntb_FinancingReceivableModificationsRecordedInvestmentNonAccrual"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancingReceivableModificationsLineItems_45b09fcc-1cb9-4dd4-9eb2-8d015627e963" xlink:to="loc_ntb_FinancingReceivableModificationsRecordedInvestmentNonAccrual_e5a558ea-aec2-452a-9e35-4cb63b699c4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Creditriskconcentrations" xlink:type="simple" xlink:href="ntb-20201231.xsd#Creditriskconcentrations"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Creditriskconcentrations" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_4adc711d-256b-4ef2-bb35-a38f4ab4a8a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_96517dba-48f3-4d15-835a-9094977c97f8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_4adc711d-256b-4ef2-bb35-a38f4ab4a8a6" xlink:to="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_96517dba-48f3-4d15-835a-9094977c97f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditriskconcentrationsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditriskconcentrationsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditriskconcentrationsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_273ad14d-f501-4e27-888d-9e19a88268c2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock_611d9c42-d15c-462d-b108-0e760ba52f50" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_273ad14d-f501-4e27-888d-9e19a88268c2" xlink:to="loc_us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock_611d9c42-d15c-462d-b108-0e760ba52f50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditriskconcentrationsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditriskconcentrationsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditriskconcentrationsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_53e98d5c-476d-4192-98f6-3937630ca025" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTable_c072ced0-45fd-4cfc-aab7-0aa575b535c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_53e98d5c-476d-4192-98f6-3937630ca025" xlink:to="loc_us-gaap_ConcentrationRiskTable_c072ced0-45fd-4cfc-aab7-0aa575b535c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_9a62473a-f6aa-40e9-8bde-4b15ee0da5fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_c072ced0-45fd-4cfc-aab7-0aa575b535c0" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_9a62473a-f6aa-40e9-8bde-4b15ee0da5fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_e933f991-5930-4694-a96c-2b756b8b3e40" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_9a62473a-f6aa-40e9-8bde-4b15ee0da5fd" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_e933f991-5930-4694-a96c-2b756b8b3e40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditAvailabilityConcentrationRiskMember_f6b817b0-e501-47ac-8814-63fae8d8dbcf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditAvailabilityConcentrationRiskMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_e933f991-5930-4694-a96c-2b756b8b3e40" xlink:to="loc_us-gaap_CreditAvailabilityConcentrationRiskMember_f6b817b0-e501-47ac-8814-63fae8d8dbcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_ac727d7f-f7a8-40c0-a8f2-19042b65a2ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_c072ced0-45fd-4cfc-aab7-0aa575b535c0" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_ac727d7f-f7a8-40c0-a8f2-19042b65a2ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_8f6f996e-220e-4571-b27b-c66af5e24cb2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_ac727d7f-f7a8-40c0-a8f2-19042b65a2ef" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_8f6f996e-220e-4571-b27b-c66af5e24cb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TotalCreditExposureMember_9183ecaf-1005-46f3-bbc7-5804abcdeef9" xlink:href="ntb-20201231.xsd#ntb_TotalCreditExposureMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_8f6f996e-220e-4571-b27b-c66af5e24cb2" xlink:to="loc_ntb_TotalCreditExposureMember_9183ecaf-1005-46f3-bbc7-5804abcdeef9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CashDueFromBanksAgreementstoResellandShorttermInvestmentsMember_2b1e7a7b-78f4-412e-9f1c-afdf1d241b97" xlink:href="ntb-20201231.xsd#ntb_CashDueFromBanksAgreementstoResellandShorttermInvestmentsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TotalCreditExposureMember_9183ecaf-1005-46f3-bbc7-5804abcdeef9" xlink:to="loc_ntb_CashDueFromBanksAgreementstoResellandShorttermInvestmentsMember_2b1e7a7b-78f4-412e-9f1c-afdf1d241b97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FinancingReceivableAfterAllowanceForCreditLossMember_d353d2c4-15eb-4cd9-992d-0b1cf0dae644" xlink:href="ntb-20201231.xsd#ntb_FinancingReceivableAfterAllowanceForCreditLossMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TotalCreditExposureMember_9183ecaf-1005-46f3-bbc7-5804abcdeef9" xlink:to="loc_ntb_FinancingReceivableAfterAllowanceForCreditLossMember_d353d2c4-15eb-4cd9-992d-0b1cf0dae644" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OffbalanceSheetMember_05171d86-0098-4af4-aefa-c1ba2260541b" xlink:href="ntb-20201231.xsd#ntb_OffbalanceSheetMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TotalCreditExposureMember_9183ecaf-1005-46f3-bbc7-5804abcdeef9" xlink:to="loc_ntb_OffbalanceSheetMember_05171d86-0098-4af4-aefa-c1ba2260541b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_f9cd49a1-2abb-4b13-962b-fcdfcdfe8e34" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementGeographicalAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_c072ced0-45fd-4cfc-aab7-0aa575b535c0" xlink:to="loc_srt_StatementGeographicalAxis_f9cd49a1-2abb-4b13-962b-fcdfcdfe8e34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_f9cd49a1-2abb-4b13-962b-fcdfcdfe8e34" xlink:to="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_AU_b2ba0752-e6f7-42cb-a317-aa6ae737d692" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_AU"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_AU_b2ba0752-e6f7-42cb-a317-aa6ae737d692" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_BE_e59713e4-9966-450a-83b7-308aafcbf156" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_BE"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_BE_e59713e4-9966-450a-83b7-308aafcbf156" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_BM_5d1fe043-d75b-462c-9c0a-458169d61ea7" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_BM"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_BM_5d1fe043-d75b-462c-9c0a-458169d61ea7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_CA_a440babb-df0b-4cb0-9689-5d27cb4390f9" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_CA"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_CA_a440babb-df0b-4cb0-9689-5d27cb4390f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_KY_cb37a5cd-efef-466c-baf8-9c91b4983daf" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_KY"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_KY_cb37a5cd-efef-466c-baf8-9c91b4983daf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_DE_f1083f3a-3b33-4d74-99b1-8032daf52ef2" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_DE"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_DE_f1083f3a-3b33-4d74-99b1-8032daf52ef2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_GG_b71ea218-39da-4cad-8e35-9f4cc908b92b" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_GG"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_GG_b71ea218-39da-4cad-8e35-9f4cc908b92b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_IE_fb95c882-04a8-466b-a4c7-b9ed868ea4ff" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_IE"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_IE_fb95c882-04a8-466b-a4c7-b9ed868ea4ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_JP_ca433deb-35f4-4680-8f98-b11be170ef4b" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_JP"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_JP_ca433deb-35f4-4680-8f98-b11be170ef4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_JE_df4f0f3c-6cd9-47b2-861e-67aa7b48ddca" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_JE"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_JE_df4f0f3c-6cd9-47b2-861e-67aa7b48ddca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_NL_3e47de9d-3401-43fc-9c5e-006784c942f5" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_NL"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_NL_3e47de9d-3401-43fc-9c5e-006784c942f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_NZ_7a3e93e1-719b-465b-9377-ff18f0016a09" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_NZ"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_NZ_7a3e93e1-719b-465b-9377-ff18f0016a09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_NO_add3c7db-47ff-42f8-864b-52ce404aed62" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_NO"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_NO_add3c7db-47ff-42f8-864b-52ce404aed62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_LC_67f26460-3495-4ce4-a0f4-4ffb33010e5d" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_LC"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_LC_67f26460-3495-4ce4-a0f4-4ffb33010e5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_CH_a4bd7cb8-8ad0-4071-8a01-ace48ccbd3f9" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_CH"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_CH_a4bd7cb8-8ad0-4071-8a01-ace48ccbd3f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_BS_ab45e4db-ef48-48ae-9b5f-4a70fb216080" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_BS"/>

<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_BS_ab45e4db-ef48-48ae-9b5f-4a70fb216080" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_GB_0a3effa3-36c5-428c-85c4-83a52d4891ee" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_GB"/>

<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_GB_0a3effa3-36c5-428c-85c4-83a52d4891ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_country_US_bba492fe-8287-4d8a-bc2f-df081972443a" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_US"/>

<link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_country_US_bba492fe-8287-4d8a-bc2f-df081972443a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherGeographicRegionsMember_a932c5c4-4a27-43f4-a34a-544d8df8886c" xlink:href="ntb-20201231.xsd#ntb_OtherGeographicRegionsMember"/>

<link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_00f2bf30-7722-4017-8415-f7fe4f8e1ae7" xlink:to="loc_ntb_OtherGeographicRegionsMember_a932c5c4-4a27-43f4-a34a-544d8df8886c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskLineItems_ed301ac1-6a3b-4f80-a1f5-54c37aaca68e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_c072ced0-45fd-4cfc-aab7-0aa575b535c0" xlink:to="loc_us-gaap_ConcentrationRiskLineItems_ed301ac1-6a3b-4f80-a1f5-54c37aaca68e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure_5a27488f-905d-42d7-898a-7683b8d59543" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_ed301ac1-6a3b-4f80-a1f5-54c37aaca68e" xlink:to="loc_us-gaap_ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure_5a27488f-905d-42d7-898a-7683b8d59543" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Premisesequipmentandcomputersoftware" xlink:type="simple" xlink:href="ntb-20201231.xsd#Premisesequipmentandcomputersoftware"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Premisesequipmentandcomputersoftware" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_19d9f678-b0b8-49d0-9761-a61ca2799900" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_2a57a5c1-40be-4e2e-b48d-2b8eeee9ce14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_19d9f678-b0b8-49d0-9761-a61ca2799900" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_2a57a5c1-40be-4e2e-b48d-2b8eeee9ce14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/PremisesequipmentandcomputersoftwareTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#PremisesequipmentandcomputersoftwareTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/PremisesequipmentandcomputersoftwareTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_038f6ce2-172f-4722-81c0-c6f8eafbc722" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_194ebb29-5e21-4f3b-851d-dff34c4d6ed8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_038f6ce2-172f-4722-81c0-c6f8eafbc722" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_194ebb29-5e21-4f3b-851d-dff34c4d6ed8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/PremisesequipmentandcomputersoftwareScheduleofPremiseEquipmentandComputerSoftwareDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#PremisesequipmentandcomputersoftwareScheduleofPremiseEquipmentandComputerSoftwareDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/PremisesequipmentandcomputersoftwareScheduleofPremiseEquipmentandComputerSoftwareDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_3127008a-0db4-4795-9617-7deb26f2e644" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_82833935-b500-42ad-ad1f-25dc3f3623c2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_3127008a-0db4-4795-9617-7deb26f2e644" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_82833935-b500-42ad-ad1f-25dc3f3623c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_b1d45572-025d-4af9-8a32-467a629b92eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_82833935-b500-42ad-ad1f-25dc3f3623c2" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_b1d45572-025d-4af9-8a32-467a629b92eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_67b170b9-8abf-4611-9c64-d779d135fa2b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_b1d45572-025d-4af9-8a32-467a629b92eb" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_67b170b9-8abf-4611-9c64-d779d135fa2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LandMember_47667a6c-2a23-40a7-ada1-573068b0a3de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LandMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_67b170b9-8abf-4611-9c64-d779d135fa2b" xlink:to="loc_us-gaap_LandMember_47667a6c-2a23-40a7-ada1-573068b0a3de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BuildingMember_18b745e8-92e8-41cc-96d6-05e5ae1c42f4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BuildingMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_67b170b9-8abf-4611-9c64-d779d135fa2b" xlink:to="loc_us-gaap_BuildingMember_18b745e8-92e8-41cc-96d6-05e5ae1c42f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquipmentMember_a5f5dbf0-664c-401a-ad2e-2d3fc8109027" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquipmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_67b170b9-8abf-4611-9c64-d779d135fa2b" xlink:to="loc_us-gaap_EquipmentMember_a5f5dbf0-664c-401a-ad2e-2d3fc8109027" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ComputerHardwareandSoftwareMember_141d94f3-fcc6-45d8-b0b4-376c7bf77901" xlink:href="ntb-20201231.xsd#ntb_ComputerHardwareandSoftwareMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_67b170b9-8abf-4611-9c64-d779d135fa2b" xlink:to="loc_ntb_ComputerHardwareandSoftwareMember_141d94f3-fcc6-45d8-b0b4-376c7bf77901" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SoftwareDevelopmentMember_8d91192a-47af-42b2-a393-99c8ecfe8ee3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SoftwareDevelopmentMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_67b170b9-8abf-4611-9c64-d779d135fa2b" xlink:to="loc_us-gaap_SoftwareDevelopmentMember_8d91192a-47af-42b2-a393-99c8ecfe8ee3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_c17bf45a-365e-4fc1-aedb-24087b1649d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_82833935-b500-42ad-ad1f-25dc3f3623c2" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_c17bf45a-365e-4fc1-aedb-24087b1649d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_080487a7-6473-49f1-ae34-c817fc7e9bdc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_c17bf45a-365e-4fc1-aedb-24087b1649d1" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_080487a7-6473-49f1-ae34-c817fc7e9bdc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_b91dae7b-534b-455e-bfcb-9f169fb97c52" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_c17bf45a-365e-4fc1-aedb-24087b1649d1" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_b91dae7b-534b-455e-bfcb-9f169fb97c52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_0599b52f-964e-4c82-806b-2490ce5c5a31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_c17bf45a-365e-4fc1-aedb-24087b1649d1" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_0599b52f-964e-4c82-806b-2490ce5c5a31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_b00bf5f1-89fc-4fff-8a41-d758c3c0e578" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Depreciation"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_c17bf45a-365e-4fc1-aedb-24087b1649d1" xlink:to="loc_us-gaap_Depreciation_b00bf5f1-89fc-4fff-8a41-d758c3c0e578" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Goodwillandotherintangibleassets" xlink:type="simple" xlink:href="ntb-20201231.xsd#Goodwillandotherintangibleassets"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Goodwillandotherintangibleassets" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_97030056-00da-4c7f-8800-23e8c742a863" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_ae634b57-dd8e-49a3-a079-c2d632d74287" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_97030056-00da-4c7f-8800-23e8c742a863" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_ae634b57-dd8e-49a3-a079-c2d632d74287" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#GoodwillandotherintangibleassetsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5241e9ec-a42c-4a6a-ad6d-9722385d93f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTextBlock_b5c6a01f-b17e-43c7-9128-e42b54668c9a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfGoodwillTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5241e9ec-a42c-4a6a-ad6d-9722385d93f2" xlink:to="loc_us-gaap_ScheduleOfGoodwillTextBlock_b5c6a01f-b17e-43c7-9128-e42b54668c9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock_f72aa9af-a960-4150-8c6d-f740e4e0e20c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5241e9ec-a42c-4a6a-ad6d-9722385d93f2" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock_f72aa9af-a960-4150-8c6d-f740e4e0e20c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsGoodwillDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#GoodwillandotherintangibleassetsGoodwillDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsGoodwillDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_1b0aa68e-7a96-4b77-b3cd-9ee074baf2b3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_eb4bb3e2-915b-430b-a94c-bda73941447a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfGoodwillTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_1b0aa68e-7a96-4b77-b3cd-9ee074baf2b3" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_eb4bb3e2-915b-430b-a94c-bda73941447a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_8fb73fb3-031f-43a4-95b0-2a01f59ed814" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_eb4bb3e2-915b-430b-a94c-bda73941447a" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_8fb73fb3-031f-43a4-95b0-2a01f59ed814" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_3e39c2c6-b427-4bbf-a5c8-7710748dfe1b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_8fb73fb3-031f-43a4-95b0-2a01f59ed814" xlink:to="loc_us-gaap_SegmentDomain_3e39c2c6-b427-4bbf-a5c8-7710748dfe1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CaymanSegmentMember_58994858-0864-465c-9eb4-f377b02c211b" xlink:href="ntb-20201231.xsd#ntb_CaymanSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_3e39c2c6-b427-4bbf-a5c8-7710748dfe1b" xlink:to="loc_ntb_CaymanSegmentMember_58994858-0864-465c-9eb4-f377b02c211b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_d81ce782-9f45-45e5-bbc0-dbf02c972474" xlink:href="ntb-20201231.xsd#ntb_ChannelIslandsAndUnitedKingdomSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_3e39c2c6-b427-4bbf-a5c8-7710748dfe1b" xlink:to="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_d81ce782-9f45-45e5-bbc0-dbf02c972474" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllOtherSegmentsMember_1ebfd0ab-0014-48f5-8bda-1d3b2dc2c967" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllOtherSegmentsMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_3e39c2c6-b427-4bbf-a5c8-7710748dfe1b" xlink:to="loc_us-gaap_AllOtherSegmentsMember_1ebfd0ab-0014-48f5-8bda-1d3b2dc2c967" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillLineItems_63691e92-0dec-4b92-9f91-2630899da97e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_eb4bb3e2-915b-430b-a94c-bda73941447a" xlink:to="loc_us-gaap_GoodwillLineItems_63691e92-0dec-4b92-9f91-2630899da97e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillRollForward_c39b6ccf-be8d-4f0b-b2cf-88b8945eb4c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillRollForward"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_63691e92-0dec-4b92-9f91-2630899da97e" xlink:to="loc_us-gaap_GoodwillRollForward_c39b6ccf-be8d-4f0b-b2cf-88b8945eb4c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_2e455dbb-8205-471c-b2d2-f9f3f67704a4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_c39b6ccf-be8d-4f0b-b2cf-88b8945eb4c8" xlink:to="loc_us-gaap_Goodwill_2e455dbb-8205-471c-b2d2-f9f3f67704a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAcquiredDuringPeriod_82e32e86-4639-4197-b492-7fb71a299b50" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAcquiredDuringPeriod"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_c39b6ccf-be8d-4f0b-b2cf-88b8945eb4c8" xlink:to="loc_us-gaap_GoodwillAcquiredDuringPeriod_82e32e86-4639-4197-b492-7fb71a299b50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_7a56feab-7d84-4aee-9a11-febd3dda2dd5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillForeignCurrencyTranslationGainLoss"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_c39b6ccf-be8d-4f0b-b2cf-88b8945eb4c8" xlink:to="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_7a56feab-7d84-4aee-9a11-febd3dda2dd5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_cccf06bf-4c61-4db6-b3e3-90530aee36ae" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_c39b6ccf-be8d-4f0b-b2cf-88b8945eb4c8" xlink:to="loc_us-gaap_Goodwill_cccf06bf-4c61-4db6-b3e3-90530aee36ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsCustomerRelationshipIntangibleAssetsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#GoodwillandotherintangibleassetsCustomerRelationshipIntangibleAssetsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsCustomerRelationshipIntangibleAssetsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_d7a2398b-f36c-4d9e-a4d8-dec6c135e911" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_06a13282-b2af-4e77-a661-bb1625bb30a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_d7a2398b-f36c-4d9e-a4d8-dec6c135e911" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_06a13282-b2af-4e77-a661-bb1625bb30a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_dc92d79e-8ede-428e-a3ef-1a125cec0e3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_06a13282-b2af-4e77-a661-bb1625bb30a9" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_dc92d79e-8ede-428e-a3ef-1a125cec0e3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_b2d67106-52ec-4982-8725-e051acf8bbfe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_dc92d79e-8ede-428e-a3ef-1a125cec0e3c" xlink:to="loc_us-gaap_SegmentDomain_b2d67106-52ec-4982-8725-e051acf8bbfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BermudaSegmentMember_ff27ad79-15bd-4643-b611-5c502e8d6a22" xlink:href="ntb-20201231.xsd#ntb_BermudaSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_b2d67106-52ec-4982-8725-e051acf8bbfe" xlink:to="loc_ntb_BermudaSegmentMember_ff27ad79-15bd-4643-b611-5c502e8d6a22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CaymanSegmentMember_d5db93b7-d867-47e9-a4ae-d8d958ebfe08" xlink:href="ntb-20201231.xsd#ntb_CaymanSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_b2d67106-52ec-4982-8725-e051acf8bbfe" xlink:to="loc_ntb_CaymanSegmentMember_d5db93b7-d867-47e9-a4ae-d8d958ebfe08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_dc41602f-87c7-4739-a114-44e6e996caf1" xlink:href="ntb-20201231.xsd#ntb_ChannelIslandsAndUnitedKingdomSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_b2d67106-52ec-4982-8725-e051acf8bbfe" xlink:to="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_dc41602f-87c7-4739-a114-44e6e996caf1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllOtherSegmentsMember_9d8494c8-0d89-4438-a0ee-4446708aa15f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllOtherSegmentsMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_b2d67106-52ec-4982-8725-e051acf8bbfe" xlink:to="loc_us-gaap_AllOtherSegmentsMember_9d8494c8-0d89-4438-a0ee-4446708aa15f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_c85b36d8-aaa0-4287-ab2a-7bfbd6db4ad6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_06a13282-b2af-4e77-a661-bb1625bb30a9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_c85b36d8-aaa0-4287-ab2a-7bfbd6db4ad6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_8e903cff-54dc-4b81-af57-e3c7954d37af" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_c85b36d8-aaa0-4287-ab2a-7bfbd6db4ad6" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_8e903cff-54dc-4b81-af57-e3c7954d37af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerRelationshipsMember_cad2dc60-50f8-4041-b2bd-507b66e9a85d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CustomerRelationshipsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_8e903cff-54dc-4b81-af57-e3c7954d37af" xlink:to="loc_us-gaap_CustomerRelationshipsMember_cad2dc60-50f8-4041-b2bd-507b66e9a85d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_aa0b2d8e-c911-444c-9305-32c325f3e87b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_06a13282-b2af-4e77-a661-bb1625bb30a9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_aa0b2d8e-c911-444c-9305-32c325f3e87b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedCustomerRelationshipsGross_cf4c6317-0ee3-4b37-8198-79f755cdd695" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedCustomerRelationshipsGross"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_aa0b2d8e-c911-444c-9305-32c325f3e87b" xlink:to="loc_us-gaap_FiniteLivedCustomerRelationshipsGross_cf4c6317-0ee3-4b37-8198-79f755cdd695" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_98ed63ab-76f3-48a6-9a12-ecf1231286a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_aa0b2d8e-c911-444c-9305-32c325f3e87b" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_98ed63ab-76f3-48a6-9a12-ecf1231286a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_72765c27-4ac9-4d52-b5dc-c7d0a581033b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_aa0b2d8e-c911-444c-9305-32c325f3e87b" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_72765c27-4ac9-4d52-b5dc-c7d0a581033b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsNarrativeDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#GoodwillandotherintangibleassetsNarrativeDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/GoodwillandotherintangibleassetsNarrativeDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_eb83ab14-9dd6-4459-a8ff-e23ee02224f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_a0010e8e-7da0-4271-8df6-dd55c8edfb48" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_eb83ab14-9dd6-4459-a8ff-e23ee02224f0" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_a0010e8e-7da0-4271-8df6-dd55c8edfb48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_3d17bc28-c36b-4af2-a4d1-209743c29be3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_a0010e8e-7da0-4271-8df6-dd55c8edfb48" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_3d17bc28-c36b-4af2-a4d1-209743c29be3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_da71b92c-88c3-4bf5-849b-ab73761c0062" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_3d17bc28-c36b-4af2-a4d1-209743c29be3" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_da71b92c-88c3-4bf5-849b-ab73761c0062" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerRelationshipsMember_ff61f27b-c6e3-417b-acd8-a58a79bf0c05" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CustomerRelationshipsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_da71b92c-88c3-4bf5-849b-ab73761c0062" xlink:to="loc_us-gaap_CustomerRelationshipsMember_ff61f27b-c6e3-417b-acd8-a58a79bf0c05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_944ca71a-7d40-40fb-97f6-a196585010e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_a0010e8e-7da0-4271-8df6-dd55c8edfb48" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_944ca71a-7d40-40fb-97f6-a196585010e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_b5034e42-d1aa-4d04-84a2-668bdfdc0274" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_944ca71a-7d40-40fb-97f6-a196585010e1" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_b5034e42-d1aa-4d04-84a2-668bdfdc0274" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DeutscheBanksGlobalTrustSolutionsMember_66df9445-eae8-4860-8129-9b3fa321fc40" xlink:href="ntb-20201231.xsd#ntb_DeutscheBanksGlobalTrustSolutionsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_b5034e42-d1aa-4d04-84a2-668bdfdc0274" xlink:to="loc_ntb_DeutscheBanksGlobalTrustSolutionsMember_66df9445-eae8-4860-8129-9b3fa321fc40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AssetAcquisitionsMember_ca267932-2e9b-4813-a432-38700d233103" xlink:href="ntb-20201231.xsd#ntb_AssetAcquisitionsMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_b5034e42-d1aa-4d04-84a2-668bdfdc0274" xlink:to="loc_ntb_AssetAcquisitionsMember_ca267932-2e9b-4813-a432-38700d233103" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_a0010e8e-7da0-4271-8df6-dd55c8edfb48" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_533c109a-8cd5-4a03-a447-649832508137" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinitelivedIntangibleAssetsAcquired1"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_533c109a-8cd5-4a03-a447-649832508137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_a48d8f63-c455-4ab1-83c3-8d07275d5c71" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_a48d8f63-c455-4ab1-83c3-8d07275d5c71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_452424ce-bc5f-4c99-88d4-cb9980783576" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_452424ce-bc5f-4c99-88d4-cb9980783576" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_95b0cf74-97cc-4910-a893-144a446aba33" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_95b0cf74-97cc-4910-a893-144a446aba33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_9dba85b7-6bc6-406e-bfaf-5649d18b105d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_9dba85b7-6bc6-406e-bfaf-5649d18b105d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_922b0f18-2755-425b-9b99-f4067757fe97" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_922b0f18-2755-425b-9b99-f4067757fe97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_84f40328-4ca3-4ff5-9a3b-0b5b2b63e418" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_84f40328-4ca3-4ff5-9a3b-0b5b2b63e418" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_d297b4f9-9136-4cb0-9878-3ddcdc8e1673" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_d297b4f9-9136-4cb0-9878-3ddcdc8e1673" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_79143773-f31c-465b-a7b4-62a677805341" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_e4665cd9-5dc5-4840-b186-65549dc77730" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_79143773-f31c-465b-a7b4-62a677805341" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Customerdepositsanddepositsfrombanks" xlink:type="simple" xlink:href="ntb-20201231.xsd#Customerdepositsanddepositsfrombanks"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Customerdepositsanddepositsfrombanks" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAbstract_40129552-f338-428c-a866-fa007b201865" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositLiabilitiesDisclosuresTextBlock_e729b2bf-fc61-4cb3-9a0d-b9378fcec36c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositLiabilitiesDisclosuresTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsAbstract_40129552-f338-428c-a866-fa007b201865" xlink:to="loc_us-gaap_DepositLiabilitiesDisclosuresTextBlock_e729b2bf-fc61-4cb3-9a0d-b9378fcec36c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CustomerdepositsanddepositsfrombanksTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#CustomerdepositsanddepositsfrombanksTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CustomerdepositsanddepositsfrombanksTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAbstract_6cf5b9ed-ba28-41de-bcd9-32c712ad59ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositMaturitiesTableTextBlock_fae96ccb-c27e-482e-b23a-819a1bd442ea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDepositMaturitiesTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsAbstract_6cf5b9ed-ba28-41de-bcd9-32c712ad59ce" xlink:to="loc_us-gaap_TimeDepositMaturitiesTableTextBlock_fae96ccb-c27e-482e-b23a-819a1bd442ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_UpdatetoDepositLiabilitiesTypeTableTextBlock_163cc6fd-fefd-429b-bb85-7a8660d17550" xlink:href="ntb-20201231.xsd#ntb_UpdatetoDepositLiabilitiesTypeTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsAbstract_6cf5b9ed-ba28-41de-bcd9-32c712ad59ce" xlink:to="loc_ntb_UpdatetoDepositLiabilitiesTypeTableTextBlock_163cc6fd-fefd-429b-bb85-7a8660d17550" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CustomerdepositsanddepositsfrombanksDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CustomerdepositsanddepositsfrombanksDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CustomerdepositsanddepositsfrombanksDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAbstract_294f514c-c2b2-47ce-a096-397d71beea57" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositsTable_79682246-d1c1-4ec5-8314-5d2cdd2fe79d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDepositsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsAbstract_294f514c-c2b2-47ce-a096-397d71beea57" xlink:to="loc_us-gaap_TimeDepositsTable_79682246-d1c1-4ec5-8314-5d2cdd2fe79d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodsAxis_19509686-0c52-4bef-a981-cfb700490088" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsTable_79682246-d1c1-4ec5-8314-5d2cdd2fe79d" xlink:to="loc_us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodsAxis_19509686-0c52-4bef-a981-cfb700490088" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodDomain_ff8faefa-9476-4a5b-9b9c-6c4052cf7583" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodsAxis_19509686-0c52-4bef-a981-cfb700490088" xlink:to="loc_us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodDomain_ff8faefa-9476-4a5b-9b9c-6c4052cf7583" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_Demandorlessthan100kMember_155a8868-dc4e-4c13-a66b-f902d05bb6de" xlink:href="ntb-20201231.xsd#ntb_Demandorlessthan100kMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodDomain_ff8faefa-9476-4a5b-9b9c-6c4052cf7583" xlink:to="loc_ntb_Demandorlessthan100kMember_155a8868-dc4e-4c13-a66b-f902d05bb6de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_Term100kormoreMember_6ad64e62-db5c-490e-823b-178a146fa267" xlink:href="ntb-20201231.xsd#ntb_Term100kormoreMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsSoldUnderAgreementsToRepurchaseMaturityPeriodDomain_ff8faefa-9476-4a5b-9b9c-6c4052cf7583" xlink:to="loc_ntb_Term100kormoreMember_6ad64e62-db5c-490e-823b-178a146fa267" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDepositsAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsTable_79682246-d1c1-4ec5-8314-5d2cdd2fe79d" xlink:to="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestBearingDomesticDepositDemand_745bc566-ec1f-4693-9184-f57a9e88ec30" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestBearingDomesticDepositDemand"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_NoninterestBearingDomesticDepositDemand_745bc566-ec1f-4693-9184-f57a9e88ec30" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDomesticDepositDemand_b0698c08-8e1f-4b92-bd39-a2b245031721" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestBearingDomesticDepositDemand"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_InterestBearingDomesticDepositDemand_b0698c08-8e1f-4b92-bd39-a2b245031721" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DemandDepositAccounts_772d2421-6157-447b-a09b-3375add4922d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DemandDepositAccounts"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_DemandDepositAccounts_772d2421-6157-447b-a09b-3375add4922d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000ThreeMonthsorLess_22d42391-1925-41e7-9bcd-32dcd9f6e9aa" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsLessThan100000ThreeMonthsorLess"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000ThreeMonthsorLess_22d42391-1925-41e7-9bcd-32dcd9f6e9aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000ThreeMonthsThroughSixMonths_036fe831-69ff-465f-ba55-f713f452a1f1" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsLessThan100000ThreeMonthsThroughSixMonths"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000ThreeMonthsThroughSixMonths_036fe831-69ff-465f-ba55-f713f452a1f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000SixMonthsThrough12Months_0e50a504-e83f-4a8d-b2e8-bce026a0f8a4" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsLessThan100000SixMonthsThrough12Months"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000SixMonthsThrough12Months_0e50a504-e83f-4a8d-b2e8-bce026a0f8a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000after12Months_d42b0763-0a61-4584-bd83-b3b24f1fceb5" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsLessThan100000after12Months"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsLessThan100000after12Months_d42b0763-0a61-4584-bd83-b3b24f1fceb5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositsLessThan100000_7c9db38e-eb8e-4a84-a118-dcad1510c628" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDepositsLessThan100000"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_TimeDepositsLessThan100000_7c9db38e-eb8e-4a84-a118-dcad1510c628" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DepositsLessthan100000_0b954b89-decb-4f8d-bb5b-4ab106ef09d2" xlink:href="ntb-20201231.xsd#ntb_DepositsLessthan100000"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_DepositsLessthan100000_0b954b89-decb-4f8d-bb5b-4ab106ef09d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreThreeMonthsOrLess_3f4f08b9-979f-4b9a-b05a-19198ad67c78" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreThreeMonthsOrLess"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreThreeMonthsOrLess_3f4f08b9-979f-4b9a-b05a-19198ad67c78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreThreeMonthsThroughSixMonths_14b80660-60b0-4ddd-861b-7e42252ec4de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreThreeMonthsThroughSixMonths"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreThreeMonthsThroughSixMonths_14b80660-60b0-4ddd-861b-7e42252ec4de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreSixMonthsThrough12Months_1b91ce5f-d292-4ecf-a050-c684512c2415" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreSixMonthsThrough12Months"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreSixMonthsThrough12Months_1b91ce5f-d292-4ecf-a050-c684512c2415" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreAfter12Months_af129d10-8236-45f1-aabc-01907c4228e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreAfter12Months"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_ContractualMaturitiesTimeDeposits100000OrMoreAfter12Months_af129d10-8236-45f1-aabc-01907c4228e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDeposits100000OrMore_c44d8ce6-bbb1-416d-831f-682b73b992da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDeposits100000OrMore"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_TimeDeposits100000OrMore_c44d8ce6-bbb1-416d-831f-682b73b992da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DepositsMorethan100000_3fcbe23d-2bb8-4b43-968a-b6baa5a69b2d" xlink:href="ntb-20201231.xsd#ntb_DepositsMorethan100000"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_DepositsMorethan100000_3fcbe23d-2bb8-4b43-968a-b6baa5a69b2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsThreeMonthsorLess_327da647-190f-4d20-a379-192373c7ab90" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsThreeMonthsorLess"/>

<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsThreeMonthsorLess_327da647-190f-4d20-a379-192373c7ab90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsThreeMonthsThroughSixMonths_b8c6706e-69cd-44df-8cb9-ed304203a792" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsThreeMonthsThroughSixMonths"/>

<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsThreeMonthsThroughSixMonths_b8c6706e-69cd-44df-8cb9-ed304203a792" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsSixMonthsThrough12Months_3e8c1c90-43a4-435b-a8ae-fea9c9b25004" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsSixMonthsThrough12Months"/>

<link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsSixMonthsThrough12Months_3e8c1c90-43a4-435b-a8ae-fea9c9b25004" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ContractualMaturitiesTimeDepositsafter12Months_78030baf-79e8-441e-a352-b0d29adb1fcf" xlink:href="ntb-20201231.xsd#ntb_ContractualMaturitiesTimeDepositsafter12Months"/>

<link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_ContractualMaturitiesTimeDepositsafter12Months_78030baf-79e8-441e-a352-b0d29adb1fcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDeposits_3d899976-2e7c-4526-9e66-4cc036fc9ffb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDeposits"/>

<link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_TimeDeposits_3d899976-2e7c-4526-9e66-4cc036fc9ffb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Deposits_f0935001-4eaf-4455-8ef8-2f45cac9ec2b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Deposits"/>

<link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_us-gaap_Deposits_f0935001-4eaf-4455-8ef8-2f45cac9ec2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_WeightedAverageInterestRateDemandDeposits_d3cfac08-c5ce-485b-bb96-b890ab71c0c1" xlink:href="ntb-20201231.xsd#ntb_WeightedAverageInterestRateDemandDeposits"/>

<link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_a0e753fb-94cb-40f0-8c9b-4510e7dbf67a" xlink:to="loc_ntb_WeightedAverageInterestRateDemandDeposits_d3cfac08-c5ce-485b-bb96-b890ab71c0c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CustomerdepositsanddepositsfrombanksByTypeandSegmentDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CustomerdepositsanddepositsfrombanksByTypeandSegmentDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CustomerdepositsanddepositsfrombanksByTypeandSegmentDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAbstract_3c2a72a2-9854-4ad5-9251-234f54cc1a28" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositsTable_bdde3093-cf52-4912-92fe-794d0faa76a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDepositsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsAbstract_3c2a72a2-9854-4ad5-9251-234f54cc1a28" xlink:to="loc_us-gaap_TimeDepositsTable_bdde3093-cf52-4912-92fe-794d0faa76a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_0bda6665-0555-467e-85db-3ee98b3d9058" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsTable_bdde3093-cf52-4912-92fe-794d0faa76a9" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_0bda6665-0555-467e-85db-3ee98b3d9058" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_91c15764-5961-47b7-b14f-81b62ac407d2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_0bda6665-0555-467e-85db-3ee98b3d9058" xlink:to="loc_us-gaap_SegmentDomain_91c15764-5961-47b7-b14f-81b62ac407d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BermudaSegmentMember_f425fa3b-d33e-4f2d-8244-955ba4ff234f" xlink:href="ntb-20201231.xsd#ntb_BermudaSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_91c15764-5961-47b7-b14f-81b62ac407d2" xlink:to="loc_ntb_BermudaSegmentMember_f425fa3b-d33e-4f2d-8244-955ba4ff234f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CaymanSegmentMember_eda74ee2-e57b-4ce9-b6a1-a9001049c258" xlink:href="ntb-20201231.xsd#ntb_CaymanSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_91c15764-5961-47b7-b14f-81b62ac407d2" xlink:to="loc_ntb_CaymanSegmentMember_eda74ee2-e57b-4ce9-b6a1-a9001049c258" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_ef584fd1-3320-4121-a119-c4f1ddc9041f" xlink:href="ntb-20201231.xsd#ntb_ChannelIslandsAndUnitedKingdomSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_91c15764-5961-47b7-b14f-81b62ac407d2" xlink:to="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_ef584fd1-3320-4121-a119-c4f1ddc9041f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDepositsAbstract_8120ab9e-4412-4d7a-96d4-11a22b44b32a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDepositsAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsTable_bdde3093-cf52-4912-92fe-794d0faa76a9" xlink:to="loc_us-gaap_TimeDepositsAbstract_8120ab9e-4412-4d7a-96d4-11a22b44b32a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DemandDepositAccounts_3ed87856-fac1-482c-a0b5-fb8c05e7be6a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DemandDepositAccounts"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_8120ab9e-4412-4d7a-96d4-11a22b44b32a" xlink:to="loc_us-gaap_DemandDepositAccounts_3ed87856-fac1-482c-a0b5-fb8c05e7be6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimeDeposits_67a3ae9c-dbb1-4d06-a4d3-bc5b11572fea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TimeDeposits"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_8120ab9e-4412-4d7a-96d4-11a22b44b32a" xlink:to="loc_us-gaap_TimeDeposits_67a3ae9c-dbb1-4d06-a4d3-bc5b11572fea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Deposits_6919d57d-854e-47d0-84fa-1c77f1516a8c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Deposits"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimeDepositsAbstract_8120ab9e-4412-4d7a-96d4-11a22b44b32a" xlink:to="loc_us-gaap_Deposits_6919d57d-854e-47d0-84fa-1c77f1516a8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Employeebenefitplans" xlink:type="simple" xlink:href="ntb-20201231.xsd#Employeebenefitplans"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Employeebenefitplans" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_17d4b817-6ab4-434a-9f5e-a1482c978840" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock_39c79e90-a908-4bca-8645-794b61867824" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_17d4b817-6ab4-434a-9f5e-a1482c978840" xlink:to="loc_us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock_39c79e90-a908-4bca-8645-794b61867824" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_b5c257ec-ebee-4b97-90e0-31a94c755cd9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangesInProjectedBenefitObligationsFairValueOfPlanAssetsAndFundedStatusOfPlanTableTextBlock_5b7be2ff-57fd-4c7a-b054-df6bad809ed9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ChangesInProjectedBenefitObligationsFairValueOfPlanAssetsAndFundedStatusOfPlanTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_b5c257ec-ebee-4b97-90e0-31a94c755cd9" xlink:to="loc_us-gaap_ChangesInProjectedBenefitObligationsFairValueOfPlanAssetsAndFundedStatusOfPlanTableTextBlock_5b7be2ff-57fd-4c7a-b054-df6bad809ed9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock_b6f18bc7-c88d-4db1-b66c-7b0564d68c09" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_b5c257ec-ebee-4b97-90e0-31a94c755cd9" xlink:to="loc_us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock_b6f18bc7-c88d-4db1-b66c-7b0564d68c09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAssumptionsUsedTableTextBlock_98324d44-3ac1-4982-b5da-346e9cc062d9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAssumptionsUsedTableTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_b5c257ec-ebee-4b97-90e0-31a94c755cd9" xlink:to="loc_us-gaap_ScheduleOfAssumptionsUsedTableTextBlock_98324d44-3ac1-4982-b5da-346e9cc062d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAllocationOfPlanAssetsTableTextBlock_fc5a20fa-26a5-4c65-9ab4-9b6810fb3de0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAllocationOfPlanAssetsTableTextBlock"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_b5c257ec-ebee-4b97-90e0-31a94c755cd9" xlink:to="loc_us-gaap_ScheduleOfAllocationOfPlanAssetsTableTextBlock_fc5a20fa-26a5-4c65-9ab4-9b6810fb3de0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfExpectedBenefitPaymentsTableTextBlock_b5f877e2-9f1d-4bf4-a945-2be724bbe8f7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfExpectedBenefitPaymentsTableTextBlock"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_b5c257ec-ebee-4b97-90e0-31a94c755cd9" xlink:to="loc_us-gaap_ScheduleOfExpectedBenefitPaymentsTableTextBlock_b5f877e2-9f1d-4bf4-a945-2be724bbe8f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansNarrativeDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansNarrativeDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansNarrativeDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_a950ac9d-c7bd-49ac-b234-21c857a7a36c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_2c4b1618-f3d3-4ccc-b10b-eb633844d5e6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_a950ac9d-c7bd-49ac-b234-21c857a7a36c" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_2c4b1618-f3d3-4ccc-b10b-eb633844d5e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanNameAxis_0d1d710b-9323-46c6-90a4-2fc0cf2d9766" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanNameAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_2c4b1618-f3d3-4ccc-b10b-eb633844d5e6" xlink:to="loc_us-gaap_RetirementPlanNameAxis_0d1d710b-9323-46c6-90a4-2fc0cf2d9766" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanNameDomain_0575a6fd-67a6-4a48-90b7-d6e444b174ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanNameAxis_0d1d710b-9323-46c6-90a4-2fc0cf2d9766" xlink:to="loc_us-gaap_RetirementPlanNameDomain_0575a6fd-67a6-4a48-90b7-d6e444b174ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PostretirementHealthCoverage2010AmendmentMember_bf5c7b4d-c916-4011-94c2-986c40c42d66" xlink:href="ntb-20201231.xsd#ntb_PostretirementHealthCoverage2010AmendmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanNameDomain_0575a6fd-67a6-4a48-90b7-d6e444b174ac" xlink:to="loc_ntb_PostretirementHealthCoverage2010AmendmentMember_bf5c7b4d-c916-4011-94c2-986c40c42d66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PostretirementHealthCoverage2011AmendmentMember_e19338af-02e0-41b4-89da-a829751ebd38" xlink:href="ntb-20201231.xsd#ntb_PostretirementHealthCoverage2011AmendmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanNameDomain_0575a6fd-67a6-4a48-90b7-d6e444b174ac" xlink:to="loc_ntb_PostretirementHealthCoverage2011AmendmentMember_e19338af-02e0-41b4-89da-a829751ebd38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PostretirementHealthCoverage2014AmendmentMember_f817a07b-bf0b-44fc-bfac-0c3384e054b0" xlink:href="ntb-20201231.xsd#ntb_PostretirementHealthCoverage2014AmendmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanNameDomain_0575a6fd-67a6-4a48-90b7-d6e444b174ac" xlink:to="loc_ntb_PostretirementHealthCoverage2014AmendmentMember_f817a07b-bf0b-44fc-bfac-0c3384e054b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_9d978a65-d94e-4d7c-aa10-0848e9c5a910" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_2c4b1618-f3d3-4ccc-b10b-eb633844d5e6" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_9d978a65-d94e-4d7c-aa10-0848e9c5a910" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_860d7e89-efc5-495c-8cd8-7c1ef067ffcc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_9d978a65-d94e-4d7c-aa10-0848e9c5a910" xlink:to="loc_us-gaap_SegmentDomain_860d7e89-efc5-495c-8cd8-7c1ef067ffcc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BermudaSegmentMember_7d6e1f4b-f0e9-42cf-b9dd-6940417a2fe6" xlink:href="ntb-20201231.xsd#ntb_BermudaSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_860d7e89-efc5-495c-8cd8-7c1ef067ffcc" xlink:to="loc_ntb_BermudaSegmentMember_7d6e1f4b-f0e9-42cf-b9dd-6940417a2fe6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_GuernseySegmentMember_75faadbe-b7ef-4fe1-b830-88885d9daf15" xlink:href="ntb-20201231.xsd#ntb_GuernseySegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_860d7e89-efc5-495c-8cd8-7c1ef067ffcc" xlink:to="loc_ntb_GuernseySegmentMember_75faadbe-b7ef-4fe1-b830-88885d9daf15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_a6f199ee-b2b5-458a-8c25-1512330b7da9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_2c4b1618-f3d3-4ccc-b10b-eb633844d5e6" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_a6f199ee-b2b5-458a-8c25-1512330b7da9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_b8531c53-eef8-4002-94f5-6e4187d2e81a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_a6f199ee-b2b5-458a-8c25-1512330b7da9" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_b8531c53-eef8-4002-94f5-6e4187d2e81a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_fea86c23-ade1-470e-acca-212f3f64c2b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_b8531c53-eef8-4002-94f5-6e4187d2e81a" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_fea86c23-ade1-470e-acca-212f3f64c2b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_e576b105-fc87-4c0d-91f9-d28dca14f68f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_b8531c53-eef8-4002-94f5-6e4187d2e81a" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_e576b105-fc87-4c0d-91f9-d28dca14f68f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_075a7c8c-8722-47c3-9b26-ffdbe3fc39a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_2c4b1618-f3d3-4ccc-b10b-eb633844d5e6" xlink:to="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_075a7c8c-8722-47c3-9b26-ffdbe3fc39a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanRemainingServicePeriod_018bb3f1-5391-4b72-930e-c236257a693c" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanRemainingServicePeriod"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_075a7c8c-8722-47c3-9b26-ffdbe3fc39a5" xlink:to="loc_ntb_DefinedBenefitPlanRemainingServicePeriod_018bb3f1-5391-4b72-930e-c236257a693c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanRemainingLifeExpectancy_81225f2f-252f-46c4-b550-a09a5d71731a" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanRemainingLifeExpectancy"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_075a7c8c-8722-47c3-9b26-ffdbe3fc39a5" xlink:to="loc_ntb_DefinedBenefitPlanRemainingLifeExpectancy_81225f2f-252f-46c4-b550-a09a5d71731a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanRemainingLifeExpectancyInactiveParticipants_abd566d3-1dc3-4469-bdb0-a42c199a9e3d" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanRemainingLifeExpectancyInactiveParticipants"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_075a7c8c-8722-47c3-9b26-ffdbe3fc39a5" xlink:to="loc_ntb_DefinedBenefitPlanRemainingLifeExpectancyInactiveParticipants_abd566d3-1dc3-4469-bdb0-a42c199a9e3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanRemainingLifeExpectancyActiveMembers_45efdd2d-c6fd-4052-b651-ef6d12877566" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanRemainingLifeExpectancyActiveMembers"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_075a7c8c-8722-47c3-9b26-ffdbe3fc39a5" xlink:to="loc_ntb_DefinedBenefitPlanRemainingLifeExpectancyActiveMembers_45efdd2d-c6fd-4052-b651-ef6d12877566" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansFinancialPositionofDefinedBenefitPlansDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansFinancialPositionofDefinedBenefitPlansDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansFinancialPositionofDefinedBenefitPlansDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_8d37dfe1-3823-4e57-9911-30fcef625718" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_cd08be14-f49b-4a9b-8f61-f88f80c3fad8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_8d37dfe1-3823-4e57-9911-30fcef625718" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_cd08be14-f49b-4a9b-8f61-f88f80c3fad8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_19bbf1a3-ce50-402e-bf35-2db7f31adb30" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_cd08be14-f49b-4a9b-8f61-f88f80c3fad8" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_19bbf1a3-ce50-402e-bf35-2db7f31adb30" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_ff805168-dc2d-458f-8e92-9222d56df599" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_19bbf1a3-ce50-402e-bf35-2db7f31adb30" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_ff805168-dc2d-458f-8e92-9222d56df599" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_69b6ed72-c9a4-4458-ace0-4499001c5dee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_ff805168-dc2d-458f-8e92-9222d56df599" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_69b6ed72-c9a4-4458-ace0-4499001c5dee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_14cb10e1-5c0f-4c08-babe-c62fcfeb2330" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_ff805168-dc2d-458f-8e92-9222d56df599" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_14cb10e1-5c0f-4c08-babe-c62fcfeb2330" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_11fb487b-3225-428c-b4e4-29826624483b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_cd08be14-f49b-4a9b-8f61-f88f80c3fad8" xlink:to="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_11fb487b-3225-428c-b4e4-29826624483b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedBenefitObligation_58b842e1-523e-4027-915c-5b54e739842e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedBenefitObligation"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_11fb487b-3225-428c-b4e4-29826624483b" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedBenefitObligation_58b842e1-523e-4027-915c-5b54e739842e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_11fb487b-3225-428c-b4e4-29826624483b" xlink:to="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligation_683d89a5-2a99-4bf6-b9c7-122550103a46" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanBenefitObligation"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligation_683d89a5-2a99-4bf6-b9c7-122550103a46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanServiceCost_75853feb-c7f0-4fb8-8619-c9341bc57eb8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanServiceCost"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanServiceCost_75853feb-c7f0-4fb8-8619-c9341bc57eb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanInterestCost_0bffe507-86fc-447b-8df4-c03aae5b34ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanInterestCost"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanInterestCost_0bffe507-86fc-447b-8df4-c03aae5b34ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid_22942445-4939-43ea-b93e-3bff06743a49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid_22942445-4939-43ea-b93e-3bff06743a49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanBenefitObligationPriorServiceCost_397f948a-48b0-4df0-8dd5-1e58c8c4d632" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanBenefitObligationPriorServiceCost"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_ntb_DefinedBenefitPlanBenefitObligationPriorServiceCost_397f948a-48b0-4df0-8dd5-1e58c8c4d632" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAmendments_63ad78e6-cc60-48f6-aed5-18a86cacb796" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAmendments"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAmendments_63ad78e6-cc60-48f6-aed5-18a86cacb796" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanSettlementsBenefitObligation_51b8d63f-82d0-4fb5-ae93-f20d47413aaa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanSettlementsBenefitObligation"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanSettlementsBenefitObligation_51b8d63f-82d0-4fb5-ae93-f20d47413aaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanActuarialGainLoss_b2dd5113-b0ca-48be-a43e-c97d17c94494" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanActuarialGainLoss"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanActuarialGainLoss_b2dd5113-b0ca-48be-a43e-c97d17c94494" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanForeignCurrencyExchangeRateChangesBenefitObligation_1f90ab4b-38f4-414f-bbe3-b4fcd51d777f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanForeignCurrencyExchangeRateChangesBenefitObligation"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanForeignCurrencyExchangeRateChangesBenefitObligation_1f90ab4b-38f4-414f-bbe3-b4fcd51d777f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligation_c0e91a4d-d18e-4162-89aa-2f9649803ec8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanBenefitObligation"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_412e4c2a-16c5-4c2b-884e-35eacce6a0f9" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligation_c0e91a4d-d18e-4162-89aa-2f9649803ec8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_11fb487b-3225-428c-b4e4-29826624483b" xlink:to="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_dc04257d-2953-471b-8867-dece98bcbadc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_dc04257d-2953-471b-8867-dece98bcbadc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssets_8b71db9a-2bc7-40c9-b830-6d15169724c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanActualReturnOnPlanAssets"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:to="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssets_8b71db9a-2bc7-40c9-b830-6d15169724c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_e4aeb968-9c25-455b-a4ac-39371a941df5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanContributionsByEmployer"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:to="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_e4aeb968-9c25-455b-a4ac-39371a941df5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanSettlementsPlanAssets_6a9c900c-2844-48d4-acc3-84133a8b73aa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanSettlementsPlanAssets"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:to="loc_us-gaap_DefinedBenefitPlanSettlementsPlanAssets_6a9c900c-2844-48d4-acc3-84133a8b73aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAssetsBenefitsPaid_63349650-83f3-43d4-bdff-4a4e55fb990b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAssetsBenefitsPaid"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAssetsBenefitsPaid_63349650-83f3-43d4-bdff-4a4e55fb990b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss_0788a7e1-3463-421d-b80b-bc68e1b1a0e2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss_0788a7e1-3463-421d-b80b-bc68e1b1a0e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_81ae470d-ed9b-4b7f-89cb-2199ff077a1d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_c9294e1c-5859-4ab5-b766-2c840787113b" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_81ae470d-ed9b-4b7f-89cb-2199ff077a1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_7f59b4f5-8bc7-402a-8ac3-588fc2b80933" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_11fb487b-3225-428c-b4e4-29826624483b" xlink:to="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_7f59b4f5-8bc7-402a-8ac3-588fc2b80933" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_d20a76a4-0cea-4f36-a5bb-d1248c75503a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_7f59b4f5-8bc7-402a-8ac3-588fc2b80933" xlink:to="loc_us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_d20a76a4-0cea-4f36-a5bb-d1248c75503a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent_47d333eb-5f5b-47c4-b2d5-a45ab6014e1e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_7f59b4f5-8bc7-402a-8ac3-588fc2b80933" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent_47d333eb-5f5b-47c4-b2d5-a45ab6014e1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_370dfdec-17e6-4999-babf-cc6f910da6ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_7f59b4f5-8bc7-402a-8ac3-588fc2b80933" xlink:to="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_370dfdec-17e6-4999-babf-cc6f910da6ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansAmountsRecognizedinAOCIBenefitExpenseIncomeandOCIDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansAmountsRecognizedinAOCIBenefitExpenseIncomeandOCIDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansAmountsRecognizedinAOCIBenefitExpenseIncomeandOCIDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_96cfecfc-1011-4d09-837d-6f787f9d16c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_72450fb6-0353-4c6d-9e49-9ec3f04ebf1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_96cfecfc-1011-4d09-837d-6f787f9d16c5" xlink:to="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_72450fb6-0353-4c6d-9e49-9ec3f04ebf1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_8ca38515-4ac2-461a-a521-e444dd0bdd0d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_72450fb6-0353-4c6d-9e49-9ec3f04ebf1a" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_8ca38515-4ac2-461a-a521-e444dd0bdd0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_af26fe89-49f3-4fc3-aa60-36ea9c5b630b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_8ca38515-4ac2-461a-a521-e444dd0bdd0d" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_af26fe89-49f3-4fc3-aa60-36ea9c5b630b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_034807cd-a986-4e5f-86d3-5b3f8b79b1f8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_af26fe89-49f3-4fc3-aa60-36ea9c5b630b" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_034807cd-a986-4e5f-86d3-5b3f8b79b1f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_9697ac89-2d34-4ef5-9b90-e1c4e47a068a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_af26fe89-49f3-4fc3-aa60-36ea9c5b630b" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_9697ac89-2d34-4ef5-9b90-e1c4e47a068a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_b9889785-4bfb-44d1-97a2-2345e2350e1d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_72450fb6-0353-4c6d-9e49-9ec3f04ebf1a" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_b9889785-4bfb-44d1-97a2-2345e2350e1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_d434ba9b-2d19-4666-98d8-67f6f6eccfb8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_b9889785-4bfb-44d1-97a2-2345e2350e1d" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_d434ba9b-2d19-4666-98d8-67f6f6eccfb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LaborAndRelatedExpenseMember_3604f415-97db-4843-9ff0-6a17db19a38c" xlink:href="ntb-20201231.xsd#ntb_LaborAndRelatedExpenseMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_d434ba9b-2d19-4666-98d8-67f6f6eccfb8" xlink:to="loc_ntb_LaborAndRelatedExpenseMember_3604f415-97db-4843-9ff0-6a17db19a38c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponentMember_e8b859aa-fa0c-4989-8371-278ae086c4b2" xlink:href="ntb-20201231.xsd#ntb_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_d434ba9b-2d19-4666-98d8-67f6f6eccfb8" xlink:to="loc_ntb_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponentMember_e8b859aa-fa0c-4989-8371-278ae086c4b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponentAndMember_d3282a29-0b63-4d91-a0c3-fc8eb2700e59" xlink:href="ntb-20201231.xsd#ntb_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponentAndMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_d434ba9b-2d19-4666-98d8-67f6f6eccfb8" xlink:to="loc_ntb_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponentAndMember_d3282a29-0b63-4d91-a0c3-fc8eb2700e59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_188baf4e-75d5-4bde-8ada-b71758a5ff78" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_72450fb6-0353-4c6d-9e49-9ec3f04ebf1a" xlink:to="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_188baf4e-75d5-4bde-8ada-b71758a5ff78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTaxAbstract_4e7cf8fa-0eb5-4aa0-a4d8-2d474bfb1637" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTaxAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_188baf4e-75d5-4bde-8ada-b71758a5ff78" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTaxAbstract_4e7cf8fa-0eb5-4aa0-a4d8-2d474bfb1637" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesAfterTax_0492972c-ef0d-40fc-9ff2-735173976445" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesAfterTax"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTaxAbstract_4e7cf8fa-0eb5-4aa0-a4d8-2d474bfb1637" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesAfterTax_0492972c-ef0d-40fc-9ff2-735173976445" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditAfterTax_e0eb5b56-3b95-4be8-933f-b84f4076d518" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditAfterTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTaxAbstract_4e7cf8fa-0eb5-4aa0-a4d8-2d474bfb1637" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditAfterTax_e0eb5b56-3b95-4be8-933f-b84f4076d518" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetTransitionAssetsObligationsAfterTax_19b8a820-1163-4cf9-8175-50a2e668d84e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetTransitionAssetsObligationsAfterTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTaxAbstract_4e7cf8fa-0eb5-4aa0-a4d8-2d474bfb1637" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetTransitionAssetsObligationsAfterTax_19b8a820-1163-4cf9-8175-50a2e668d84e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_50a58b0a-7c75-40b1-9b43-12ff72a201a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTaxAbstract_4e7cf8fa-0eb5-4aa0-a4d8-2d474bfb1637" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_50a58b0a-7c75-40b1-9b43-12ff72a201a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanandDefinedContributionPlanNetPeriodicBenefitCostAbstract_7175033a-fe2a-4a40-b3c5-533708526d19" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanandDefinedContributionPlanNetPeriodicBenefitCostAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_188baf4e-75d5-4bde-8ada-b71758a5ff78" xlink:to="loc_ntb_DefinedBenefitPlanandDefinedContributionPlanNetPeriodicBenefitCostAbstract_7175033a-fe2a-4a40-b3c5-533708526d19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_DefinedBenefitPlanandDefinedContributionPlanNetPeriodicBenefitCostAbstract_7175033a-fe2a-4a40-b3c5-533708526d19" xlink:to="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanServiceCost_23a8b273-e72b-4680-8e4f-48e868dc0814" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanServiceCost"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:to="loc_us-gaap_DefinedBenefitPlanServiceCost_23a8b273-e72b-4680-8e4f-48e868dc0814" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanInterestCost_e3657371-5893-4b7f-9c18-2f3c151eaafe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanInterestCost"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:to="loc_us-gaap_DefinedBenefitPlanInterestCost_e3657371-5893-4b7f-9c18-2f3c151eaafe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_16d9560a-5d1c-4a3c-a90e-d73ecc48e2d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_16d9560a-5d1c-4a3c-a90e-d73ecc48e2d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_1133467e-348d-43af-8fcc-614c2f68becb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_1133467e-348d-43af-8fcc-614c2f68becb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit_a95ff2f1-ddc1-4b0f-a461-1b404254dc46" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit_a95ff2f1-ddc1-4b0f-a461-1b404254dc46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlements1_b39e31ff-89ad-41cf-894d-7d224d6694a2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlements1"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCostAbstract_1c75ea21-95e6-4d77-bd82-36898183c206" xlink:to="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlements1_b39e31ff-89ad-41cf-894d-7d224d6694a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_63e3fc22-8a49-4114-9602-6aa139de3d2e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_DefinedBenefitPlanandDefinedContributionPlanNetPeriodicBenefitCostAbstract_7175033a-fe2a-4a40-b3c5-533708526d19" xlink:to="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_63e3fc22-8a49-4114-9602-6aa139de3d2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedContributionPlanCostRecognized_d8d32406-c626-45b9-b982-711b402e851f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedContributionPlanCostRecognized"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_DefinedBenefitPlanandDefinedContributionPlanNetPeriodicBenefitCostAbstract_7175033a-fe2a-4a40-b3c5-533708526d19" xlink:to="loc_us-gaap_DefinedContributionPlanCostRecognized_d8d32406-c626-45b9-b982-711b402e851f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementBenefitExpense_2b21b2cf-6038-456d-a249-d41618b08402" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionAndOtherPostretirementBenefitExpense"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_DefinedBenefitPlanandDefinedContributionPlanNetPeriodicBenefitCostAbstract_7175033a-fe2a-4a40-b3c5-533708526d19" xlink:to="loc_us-gaap_PensionAndOtherPostretirementBenefitExpense_2b21b2cf-6038-456d-a249-d41618b08402" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_188baf4e-75d5-4bde-8ada-b71758a5ff78" xlink:to="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansNetUnamortizedGainLossArisingDuringPeriodNetOfTax_0e08b9ad-cf9c-42d5-b400-ff8acdf892e8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansNetUnamortizedGainLossArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansNetUnamortizedGainLossArisingDuringPeriodNetOfTax_0e08b9ad-cf9c-42d5-b400-ff8acdf892e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostsCreditArisingDuringPeriodNetOfTax_55680022-6447-44d0-baec-f4d53c5a8158" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostsCreditArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostsCreditArisingDuringPeriodNetOfTax_55680022-6447-44d0-baec-f4d53c5a8158" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax_21b690ad-cea6-492c-a2e9-521d7fffa278" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax_21b690ad-cea6-492c-a2e9-521d7fffa278" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditNetOfTax_3fa2a70c-7fde-4ba7-8a35-38a326199b21" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditNetOfTax"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditNetOfTax_3fa2a70c-7fde-4ba7-8a35-38a326199b21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetTransitionAssetObligationNetOfTax_f34b1eac-eba6-4093-8de6-8b9ee3f47f5c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetTransitionAssetObligationNetOfTax"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetTransitionAssetObligationNetOfTax_f34b1eac-eba6-4093-8de6-8b9ee3f47f5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossPensionandOtherPostretirementBenefitPlansForeignExchangeAdjustmentnetofTax_822a8b73-5647-4c2a-807c-af00f9c7434f" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossPensionandOtherPostretirementBenefitPlansForeignExchangeAdjustmentnetofTax"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:to="loc_ntb_OtherComprehensiveIncomeLossPensionandOtherPostretirementBenefitPlansForeignExchangeAdjustmentnetofTax_822a8b73-5647-4c2a-807c-af00f9c7434f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_0077c7f3-e398-4825-9d35-0f3b4cdc1860" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInOtherComprehensiveIncomeAbstract_8f2fd6b0-bbd2-46cd-b6f0-6333e38bada1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_0077c7f3-e398-4825-9d35-0f3b4cdc1860" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansActuarialAssumptionsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansActuarialAssumptionsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansActuarialAssumptionsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_53c7c77e-7fc5-442c-ba8c-6e8bf1653e5c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_18cc0dc8-b278-43c7-91cd-7175bfa179ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_53c7c77e-7fc5-442c-ba8c-6e8bf1653e5c" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_18cc0dc8-b278-43c7-91cd-7175bfa179ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_65b7313e-76e5-4210-8fd0-f86badf99aff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_18cc0dc8-b278-43c7-91cd-7175bfa179ac" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_65b7313e-76e5-4210-8fd0-f86badf99aff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_3b976918-b78e-4727-8a72-7e5c2016b01b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_65b7313e-76e5-4210-8fd0-f86badf99aff" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_3b976918-b78e-4727-8a72-7e5c2016b01b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_ab317745-8f40-483c-b216-4cf7b07655a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_3b976918-b78e-4727-8a72-7e5c2016b01b" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_ab317745-8f40-483c-b216-4cf7b07655a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_e92f92fe-43aa-4407-9462-ebeba44a3484" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_3b976918-b78e-4727-8a72-7e5c2016b01b" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_e92f92fe-43aa-4407-9462-ebeba44a3484" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_c594a43d-5343-4b0d-9b7c-d0e8acd8d9d8" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_18cc0dc8-b278-43c7-91cd-7175bfa179ac" xlink:to="loc_srt_RangeAxis_c594a43d-5343-4b0d-9b7c-d0e8acd8d9d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_2cb0c69d-f27f-4cf5-8d3e-86cc1aef0547" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_c594a43d-5343-4b0d-9b7c-d0e8acd8d9d8" xlink:to="loc_srt_RangeMember_2cb0c69d-f27f-4cf5-8d3e-86cc1aef0547" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_3d48503e-d329-4719-9519-9812194923df" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_2cb0c69d-f27f-4cf5-8d3e-86cc1aef0547" xlink:to="loc_srt_MaximumMember_3d48503e-d329-4719-9519-9812194923df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_91c92e92-ffd3-4ca4-bd0f-140a3a9155c3" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_2cb0c69d-f27f-4cf5-8d3e-86cc1aef0547" xlink:to="loc_srt_MinimumMember_91c92e92-ffd3-4ca4-bd0f-140a3a9155c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_8de58224-0953-454c-91f8-7f5d1e60546c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_18cc0dc8-b278-43c7-91cd-7175bfa179ac" xlink:to="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_8de58224-0953-454c-91f8-7f5d1e60546c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingNetPeriodicBenefitCostAbstract_36ef9d1c-bf25-4109-a053-9895c2999466" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingNetPeriodicBenefitCostAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_8de58224-0953-454c-91f8-7f5d1e60546c" xlink:to="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingNetPeriodicBenefitCostAbstract_36ef9d1c-bf25-4109-a053-9895c2999466" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostDiscountRate_c4a92468-f090-42d0-8856-7765854d23fb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostDiscountRate"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingNetPeriodicBenefitCostAbstract_36ef9d1c-bf25-4109-a053-9895c2999466" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostDiscountRate_c4a92468-f090-42d0-8856-7765854d23fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostRateOfCompensationIncrease_320d3786-604f-43d7-811a-995cdd6a983e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostRateOfCompensationIncrease"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingNetPeriodicBenefitCostAbstract_36ef9d1c-bf25-4109-a053-9895c2999466" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostRateOfCompensationIncrease_320d3786-604f-43d7-811a-995cdd6a983e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets_7a4fcd87-a143-4d14-881a-e494524d9fac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingNetPeriodicBenefitCostAbstract_36ef9d1c-bf25-4109-a053-9895c2999466" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets_7a4fcd87-a143-4d14-881a-e494524d9fac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanUltimateHealthCareCostTrendRateNetPeriodicBenefitCost_de9e65bc-7cfe-4b95-82a3-50fc14089ef1" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanUltimateHealthCareCostTrendRateNetPeriodicBenefitCost"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingNetPeriodicBenefitCostAbstract_36ef9d1c-bf25-4109-a053-9895c2999466" xlink:to="loc_ntb_DefinedBenefitPlanUltimateHealthCareCostTrendRateNetPeriodicBenefitCost_de9e65bc-7cfe-4b95-82a3-50fc14089ef1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingBenefitObligationAbstract_c52c4476-580a-4fe8-9f78-052303f0e321" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingBenefitObligationAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_8de58224-0953-454c-91f8-7f5d1e60546c" xlink:to="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingBenefitObligationAbstract_c52c4476-580a-4fe8-9f78-052303f0e321" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate_0832ecab-bed7-46a8-9117-176714dc4973" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingBenefitObligationAbstract_c52c4476-580a-4fe8-9f78-052303f0e321" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate_0832ecab-bed7-46a8-9117-176714dc4973" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationRateOfCompensationIncrease_19ccfac5-e7db-408f-9df7-f2c1ed2d3c81" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationRateOfCompensationIncrease"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingBenefitObligationAbstract_c52c4476-580a-4fe8-9f78-052303f0e321" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationRateOfCompensationIncrease_19ccfac5-e7db-408f-9df7-f2c1ed2d3c81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DefinedBenefitPlanUltimateHealthCareCostTrendRateBenefitObligation_67322779-2fc5-4cf2-a4ea-b73ad74b4c44" xlink:href="ntb-20201231.xsd#ntb_DefinedBenefitPlanUltimateHealthCareCostTrendRateBenefitObligation"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssumptionsUsedInCalculatingBenefitObligationAbstract_c52c4476-580a-4fe8-9f78-052303f0e321" xlink:to="loc_ntb_DefinedBenefitPlanUltimateHealthCareCostTrendRateBenefitObligation_67322779-2fc5-4cf2-a4ea-b73ad74b4c44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansInvestmentsPoliciesandStrategiesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansInvestmentsPoliciesandStrategiesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansInvestmentsPoliciesandStrategiesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_c9429dbe-7198-481a-8bff-9efd6f65b8da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_b8b7282f-b549-450c-858c-264c01bfdc32" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_c9429dbe-7198-481a-8bff-9efd6f65b8da" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_b8b7282f-b549-450c-858c-264c01bfdc32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_2db508fc-7c7d-43e6-8c3d-f2113a267087" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_b8b7282f-b549-450c-858c-264c01bfdc32" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_2db508fc-7c7d-43e6-8c3d-f2113a267087" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_2ae41dbd-5cd9-4aa3-9850-9c5ccd72438b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_2db508fc-7c7d-43e6-8c3d-f2113a267087" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_2ae41dbd-5cd9-4aa3-9850-9c5ccd72438b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_86b52aca-dbe3-4355-aca7-187df554deaa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_2ae41dbd-5cd9-4aa3-9850-9c5ccd72438b" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_86b52aca-dbe3-4355-aca7-187df554deaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_cd9884cf-ecc1-423a-8834-23bcd13eabc5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_b8b7282f-b549-450c-858c-264c01bfdc32" xlink:to="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_cd9884cf-ecc1-423a-8834-23bcd13eabc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_8e7f85c4-8959-4665-aeed-8297b62fc14d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_cd9884cf-ecc1-423a-8834-23bcd13eabc5" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_8e7f85c4-8959-4665-aeed-8297b62fc14d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDebtSecurityMember_77e47152-f76e-4f7a-900c-33fa16e54370" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDebtSecurityMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_8e7f85c4-8959-4665-aeed-8297b62fc14d" xlink:to="loc_us-gaap_DefinedBenefitPlanDebtSecurityMember_77e47152-f76e-4f7a-900c-33fa16e54370" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesMember_f085a40d-6a41-4ea4-8296-b13e3ace2dde" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanEquitySecuritiesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_8e7f85c4-8959-4665-aeed-8297b62fc14d" xlink:to="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesMember_f085a40d-6a41-4ea4-8296-b13e3ace2dde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember_10abe036-aed7-4a36-ade4-f5a4a3922047" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_8e7f85c4-8959-4665-aeed-8297b62fc14d" xlink:to="loc_us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember_10abe036-aed7-4a36-ade4-f5a4a3922047" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_e10f151f-3a5a-45d1-9436-be83ac750aa7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_b8b7282f-b549-450c-858c-264c01bfdc32" xlink:to="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_e10f151f-3a5a-45d1-9436-be83ac750aa7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract_f6bc26a0-d83a-4670-bfc8-b09f6cc2c3a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_e10f151f-3a5a-45d1-9436-be83ac750aa7" xlink:to="loc_us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract_f6bc26a0-d83a-4670-bfc8-b09f6cc2c3a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssetAllocations_b0343f72-5258-4925-83ff-bbd8944024ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanWeightedAverageAssetAllocations"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract_f6bc26a0-d83a-4670-bfc8-b09f6cc2c3a9" xlink:to="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssetAllocations_b0343f72-5258-4925-83ff-bbd8944024ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAssetsTargetAllocationPercentage_ebd7638e-acda-408f-8cc7-082ead2265ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAssetsTargetAllocationPercentage"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract_f6bc26a0-d83a-4670-bfc8-b09f6cc2c3a9" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAssetsTargetAllocationPercentage_ebd7638e-acda-408f-8cc7-082ead2265ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansFairValueMeasurementsofPensionPlansAssetsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansFairValueMeasurementsofPensionPlansAssetsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansFairValueMeasurementsofPensionPlansAssetsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_dfa57bfd-bd76-47ce-93b1-724c5e2050d8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_f1faa39a-16f1-47f2-8d34-e8f00f6aea7e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_dfa57bfd-bd76-47ce-93b1-724c5e2050d8" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_f1faa39a-16f1-47f2-8d34-e8f00f6aea7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_0e5b3f8c-b6b2-4eb3-b1e9-11d11df5baed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_f1faa39a-16f1-47f2-8d34-e8f00f6aea7e" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_0e5b3f8c-b6b2-4eb3-b1e9-11d11df5baed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_14edf8f3-d3d0-46db-9c47-c428fccbedb5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_0e5b3f8c-b6b2-4eb3-b1e9-11d11df5baed" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_14edf8f3-d3d0-46db-9c47-c428fccbedb5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_2ca57223-bba5-4f8b-892b-59d4004567b9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_14edf8f3-d3d0-46db-9c47-c428fccbedb5" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_2ca57223-bba5-4f8b-892b-59d4004567b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_7764d5da-754d-4cdc-a50e-f1de7af401c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_f1faa39a-16f1-47f2-8d34-e8f00f6aea7e" xlink:to="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_7764d5da-754d-4cdc-a50e-f1de7af401c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_7764d5da-754d-4cdc-a50e-f1de7af401c0" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryAndGovernmentMember_36d3a6d2-ac71-47e6-b787-098a48984f86" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USTreasuryAndGovernmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:to="loc_us-gaap_USTreasuryAndGovernmentMember_36d3a6d2-ac71-47e6-b787-098a48984f86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_779e094c-1702-431b-a492-5cf6a1a2afb2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_779e094c-1702-431b-a492-5cf6a1a2afb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_e080ea3a-bdfe-4df0-bf42-4cbff87b6890" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CorporateDebtSecuritiesMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_e080ea3a-bdfe-4df0-bf42-4cbff87b6890" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesMember_fc90c163-3dae-40a9-badb-7e29bd223667" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanEquitySecuritiesMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:to="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesMember_fc90c163-3dae-40a9-badb-7e29bd223667" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember_621a76df-981c-431c-8ee7-ce8e9af0b2ff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:to="loc_us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember_621a76df-981c-431c-8ee7-ce8e9af0b2ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_MutualFundsAndEquitySecuritiesManagedOrAdministeredByWhollyOwnedSubsidiariesMember_4d25976c-f409-4c0b-822a-d4735a139a5f" xlink:href="ntb-20201231.xsd#ntb_MutualFundsAndEquitySecuritiesManagedOrAdministeredByWhollyOwnedSubsidiariesMember"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:to="loc_ntb_MutualFundsAndEquitySecuritiesManagedOrAdministeredByWhollyOwnedSubsidiariesMember_4d25976c-f409-4c0b-822a-d4735a139a5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ParentCompanyCommonStockMember_91816b77-24a9-478d-bcb9-8d97ee448844" xlink:href="ntb-20201231.xsd#ntb_ParentCompanyCommonStockMember"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_abbbe683-cf67-4875-be16-4402aa281ce4" xlink:to="loc_ntb_ParentCompanyCommonStockMember_91816b77-24a9-478d-bcb9-8d97ee448844" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1e02ff59-f5e3-45f9-9ea8-e6ee8c2f0953" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_f1faa39a-16f1-47f2-8d34-e8f00f6aea7e" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1e02ff59-f5e3-45f9-9ea8-e6ee8c2f0953" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d0c2a42c-ae8a-414c-9da1-633b039af7c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1e02ff59-f5e3-45f9-9ea8-e6ee8c2f0953" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d0c2a42c-ae8a-414c-9da1-633b039af7c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_a46946dd-b871-466d-bd93-e38c696c4f91" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d0c2a42c-ae8a-414c-9da1-633b039af7c0" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_a46946dd-b871-466d-bd93-e38c696c4f91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_18f99de1-5a71-46f1-bf3e-acf3e99a47c3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d0c2a42c-ae8a-414c-9da1-633b039af7c0" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_18f99de1-5a71-46f1-bf3e-acf3e99a47c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_fa8ac5c1-0b05-4579-82ef-3510682ea76f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d0c2a42c-ae8a-414c-9da1-633b039af7c0" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_fa8ac5c1-0b05-4579-82ef-3510682ea76f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_9e1ff655-f9af-4cc0-9e82-39976c2e4a9a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_f1faa39a-16f1-47f2-8d34-e8f00f6aea7e" xlink:to="loc_us-gaap_StatementClassOfStockAxis_9e1ff655-f9af-4cc0-9e82-39976c2e4a9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_fbc1b3e0-f6b6-4775-9c63-110fbfdaa865" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_9e1ff655-f9af-4cc0-9e82-39976c2e4a9a" xlink:to="loc_us-gaap_ClassOfStockDomain_fbc1b3e0-f6b6-4775-9c63-110fbfdaa865" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonClassAMember_1efc147e-85e6-4851-88eb-d636587e2dcc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonClassAMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_fbc1b3e0-f6b6-4775-9c63-110fbfdaa865" xlink:to="loc_us-gaap_CommonClassAMember_1efc147e-85e6-4851-88eb-d636587e2dcc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_af51c800-38ce-46b9-ab23-c8dde53faaec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_f1faa39a-16f1-47f2-8d34-e8f00f6aea7e" xlink:to="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_af51c800-38ce-46b9-ab23-c8dde53faaec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_a0571937-272c-4afe-bb65-f46a06c7cdb2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_af51c800-38ce-46b9-ab23-c8dde53faaec" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_a0571937-272c-4afe-bb65-f46a06c7cdb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssetAllocations_f5f5779e-17f4-4809-ab7c-97bff1dbc95e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanWeightedAverageAssetAllocations"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_af51c800-38ce-46b9-ab23-c8dde53faaec" xlink:to="loc_us-gaap_DefinedBenefitPlanWeightedAverageAssetAllocations_f5f5779e-17f4-4809-ab7c-97bff1dbc95e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EmployeebenefitplansEstimatedFutureContributionsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EmployeebenefitplansEstimatedFutureContributionsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EmployeebenefitplansEstimatedFutureContributionsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_31ec2673-50a5-489e-b488-f614a431d96f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_e242a22b-7d33-43ec-8eb5-c0ddb7d0cac4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_31ec2673-50a5-489e-b488-f614a431d96f" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_e242a22b-7d33-43ec-8eb5-c0ddb7d0cac4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_3f8f9150-135a-4ef7-8cf7-8686b2525d6c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_e242a22b-7d33-43ec-8eb5-c0ddb7d0cac4" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_3f8f9150-135a-4ef7-8cf7-8686b2525d6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_40b4e4e1-926b-49ce-b5b6-1980f22f461c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_3f8f9150-135a-4ef7-8cf7-8686b2525d6c" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_40b4e4e1-926b-49ce-b5b6-1980f22f461c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_4463dc9d-bc41-40ec-90f7-863e5b6b8d94" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_40b4e4e1-926b-49ce-b5b6-1980f22f461c" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_4463dc9d-bc41-40ec-90f7-863e5b6b8d94" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_74cd4523-1e11-4d97-b542-14e59b91f156" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_40b4e4e1-926b-49ce-b5b6-1980f22f461c" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_74cd4523-1e11-4d97-b542-14e59b91f156" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_a30cf499-e7c7-4fe6-91cb-55b8b9f66638" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_e242a22b-7d33-43ec-8eb5-c0ddb7d0cac4" xlink:to="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_a30cf499-e7c7-4fe6-91cb-55b8b9f66638" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureEmployerContributionsNextFiscalYear_123d8102-2283-41a8-aaaa-f090da93e097" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureEmployerContributionsNextFiscalYear"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_a30cf499-e7c7-4fe6-91cb-55b8b9f66638" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureEmployerContributionsNextFiscalYear_123d8102-2283-41a8-aaaa-f090da93e097" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_a30cf499-e7c7-4fe6-91cb-55b8b9f66638" xlink:to="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsNextTwelveMonths_58c30f78-3ac6-4759-8333-5a84a3a34c98" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsNextTwelveMonths"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsNextTwelveMonths_58c30f78-3ac6-4759-8333-5a84a3a34c98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearTwo_2e33ad73-a9e2-4ab7-a965-2fb97b7124f3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearTwo"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearTwo_2e33ad73-a9e2-4ab7-a965-2fb97b7124f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearThree_fbec9792-b1b2-487f-8588-647d46aecb71" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearThree"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearThree_fbec9792-b1b2-487f-8588-647d46aecb71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFour_dda23371-39d5-4899-bf80-703e9a4352d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFour"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFour_dda23371-39d5-4899-bf80-703e9a4352d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFive_24333564-62af-4c14-b714-0bdc3d560f3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFive"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFive_24333564-62af-4c14-b714-0bdc3d560f3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsFiveFiscalYearsThereafter_4d8b02e3-fd49-48e8-9a6c-7ec753823a8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsFiveFiscalYearsThereafter"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanEstimatedFutureBenefitPaymentsAbstract_5dc5ac5a-e79c-4243-9d8d-70f72530e840" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsFiveFiscalYearsThereafter_4d8b02e3-fd49-48e8-9a6c-7ec753823a8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Creditrelatedarrangementsrepurchaseagreementsandcommitments" xlink:type="simple" xlink:href="ntb-20201231.xsd#Creditrelatedarrangementsrepurchaseagreementsandcommitments"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Creditrelatedarrangementsrepurchaseagreementsandcommitments" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_6b68ad38-af39-48cb-89d0-8cf9e9685168" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsContingenciesAndGuaranteesTextBlock_81ff4060-7e23-4e62-98fe-8cf0b08e0fa6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsContingenciesAndGuaranteesTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_6b68ad38-af39-48cb-89d0-8cf9e9685168" xlink:to="loc_us-gaap_CommitmentsContingenciesAndGuaranteesTextBlock_81ff4060-7e23-4e62-98fe-8cf0b08e0fa6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditrelatedarrangementsrepurchaseagreementsandcommitmentsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_8eaaf984-a560-4a7a-9c2c-cc37e99f9886" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ContractualObligationFiscalYearMaturityScheduleTableTextBlock_0b5da44d-65a0-4a57-948d-e2810faa6efe" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ContractualObligationFiscalYearMaturityScheduleTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_8eaaf984-a560-4a7a-9c2c-cc37e99f9886" xlink:to="loc_srt_ContractualObligationFiscalYearMaturityScheduleTableTextBlock_0b5da44d-65a0-4a57-948d-e2810faa6efe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SummaryofOutstandingUnfundedCommitmentstoExtendCreditTableTextBlock_3bb92c46-54f0-4535-82d4-e12d23f40bac" xlink:href="ntb-20201231.xsd#ntb_SummaryofOutstandingUnfundedCommitmentstoExtendCreditTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_8eaaf984-a560-4a7a-9c2c-cc37e99f9886" xlink:to="loc_ntb_SummaryofOutstandingUnfundedCommitmentstoExtendCreditTableTextBlock_3bb92c46-54f0-4535-82d4-e12d23f40bac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGuaranteeObligationsTextBlock_daebad64-5e81-484e-9cfc-d29d73a66bda" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfGuaranteeObligationsTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_8eaaf984-a560-4a7a-9c2c-cc37e99f9886" xlink:to="loc_us-gaap_ScheduleOfGuaranteeObligationsTextBlock_daebad64-5e81-484e-9cfc-d29d73a66bda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsCommitmentsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditrelatedarrangementsrepurchaseagreementsandcommitmentsCommitmentsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsCommitmentsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_0935f0e6-3d9f-4a02-b334-1cf87fda93a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable_bbe69205-cb49-437a-be1c-d077130d4958" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_0935f0e6-3d9f-4a02-b334-1cf87fda93a8" xlink:to="loc_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable_bbe69205-cb49-437a-be1c-d077130d4958" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_ade82267-46c5-4492-9e26-3d7715e55d21" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CounterpartyNameAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable_bbe69205-cb49-437a-be1c-d077130d4958" xlink:to="loc_srt_CounterpartyNameAxis_ade82267-46c5-4492-9e26-3d7715e55d21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_de1712b0-81c6-4233-81e9-b983a1757340" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_ade82267-46c5-4492-9e26-3d7715e55d21" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_de1712b0-81c6-4233-81e9-b983a1757340" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CustodianMember_26cb5bd6-b73d-4ab1-9ce1-095566f54685" xlink:href="ntb-20201231.xsd#ntb_CustodianMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_de1712b0-81c6-4233-81e9-b983a1757340" xlink:to="loc_ntb_CustodianMember_26cb5bd6-b73d-4ab1-9ce1-095566f54685" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_28005bf6-af49-4896-9f06-5a7f68394550" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable_bbe69205-cb49-437a-be1c-d077130d4958" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_28005bf6-af49-4896-9f06-5a7f68394550" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_a9fb881a-e7ef-4cf4-951a-fd665f9dc247" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_28005bf6-af49-4896-9f06-5a7f68394550" xlink:to="loc_us-gaap_LossContingencyNatureDomain_a9fb881a-e7ef-4cf4-951a-fd665f9dc247" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StandbyLettersOfCreditMember_6c6aeaeb-42eb-4023-8870-d3c0de1eb6c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StandbyLettersOfCreditMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyNatureDomain_a9fb881a-e7ef-4cf4-951a-fd665f9dc247" xlink:to="loc_us-gaap_StandbyLettersOfCreditMember_6c6aeaeb-42eb-4023-8870-d3c0de1eb6c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable_bbe69205-cb49-437a-be1c-d077130d4958" xlink:to="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligation_168c088f-01ee-401e-a975-dbaf9ff7eadb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligation"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:to="loc_us-gaap_PurchaseObligation_168c088f-01ee-401e-a975-dbaf9ff7eadb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CommitmentstoExtendCreditNumberofCustodians_ca939572-f528-4bb3-8624-0c75fa7f00fc" xlink:href="ntb-20201231.xsd#ntb_CommitmentstoExtendCreditNumberofCustodians"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:to="loc_ntb_CommitmentstoExtendCreditNumberofCustodians_ca939572-f528-4bb3-8624-0c75fa7f00fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_RighttoSetOffAgainstSecuritiesHeldPercentofUtilizedFacility_7e370bef-14e3-4f34-a492-c5c55a1cb133" xlink:href="ntb-20201231.xsd#ntb_RighttoSetOffAgainstSecuritiesHeldPercentofUtilizedFacility"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:to="loc_ntb_RighttoSetOffAgainstSecuritiesHeldPercentofUtilizedFacility_7e370bef-14e3-4f34-a492-c5c55a1cb133" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueDisclosureOffbalanceSheetRisksAmountCommitmentsToExtendCreditLiability_77666c2d-1ecb-4063-a087-b4fbfe215372" xlink:href="ntb-20201231.xsd#ntb_FairValueDisclosureOffbalanceSheetRisksAmountCommitmentsToExtendCreditLiability"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:to="loc_ntb_FairValueDisclosureOffbalanceSheetRisksAmountCommitmentsToExtendCreditLiability_77666c2d-1ecb-4063-a087-b4fbfe215372" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueDisclosureOffbalanceSheetRisksAmountDocumentaryAndCommercialLettersOfCreditLiability_4fe44632-86aa-41c3-b36f-bebca2555608" xlink:href="ntb-20201231.xsd#ntb_FairValueDisclosureOffbalanceSheetRisksAmountDocumentaryAndCommercialLettersOfCreditLiability"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:to="loc_ntb_FairValueDisclosureOffbalanceSheetRisksAmountDocumentaryAndCommercialLettersOfCreditLiability_4fe44632-86aa-41c3-b36f-bebca2555608" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability_f8e0cfc8-c23d-4e64-ba1a-b9a973d31d97" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:to="loc_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability_f8e0cfc8-c23d-4e64-ba1a-b9a973d31d97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueDisclosureOffBalanceSheetRisksAmountFinancingReceivableAllowanceForCreditLoss_eba5e4f1-5ede-4531-b968-fe51ad40fa75" xlink:href="ntb-20201231.xsd#ntb_FairValueDisclosureOffBalanceSheetRisksAmountFinancingReceivableAllowanceForCreditLoss"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueOffBalanceSheetRisksDisclosureInformationLineItems_5d02c3a2-7d67-4dfd-8e1f-ea92afb95751" xlink:to="loc_ntb_FairValueDisclosureOffBalanceSheetRisksAmountFinancingReceivableAllowanceForCreditLoss_eba5e4f1-5ede-4531-b968-fe51ad40fa75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsContractualObligationFiscalYearMaturityScheduleDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditrelatedarrangementsrepurchaseagreementsandcommitmentsContractualObligationFiscalYearMaturityScheduleDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsContractualObligationFiscalYearMaturityScheduleDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_86e6d157-615c-45c8-8f8c-a2f1702c9d21" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligationFiscalYearMaturityAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_86e6d157-615c-45c8-8f8c-a2f1702c9d21" xlink:to="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_fd21f0d1-4987-4fac-8e09-8a89c7ee7192" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligationDueInNextTwelveMonths"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:to="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_fd21f0d1-4987-4fac-8e09-8a89c7ee7192" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInSecondYear_c2be8b96-2122-486b-a388-69b19e816428" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligationDueInSecondYear"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:to="loc_us-gaap_PurchaseObligationDueInSecondYear_c2be8b96-2122-486b-a388-69b19e816428" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInThirdYear_6d886c92-4a54-4d1c-9508-8f5945be248d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligationDueInThirdYear"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:to="loc_us-gaap_PurchaseObligationDueInThirdYear_6d886c92-4a54-4d1c-9508-8f5945be248d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInFourthYear_40deaa65-66cd-435d-b1e7-3719b724a446" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligationDueInFourthYear"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:to="loc_us-gaap_PurchaseObligationDueInFourthYear_40deaa65-66cd-435d-b1e7-3719b724a446" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInFifthYear_db211fab-2419-468d-92c2-9f13140f864c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligationDueInFifthYear"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:to="loc_us-gaap_PurchaseObligationDueInFifthYear_db211fab-2419-468d-92c2-9f13140f864c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligation_fc0538dd-a228-457b-a710-e3687ae9315b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligation"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PurchaseObligationFiscalYearMaturityAbstract_6ed3d1f3-b6b8-4214-b3d3-36994808b4be" xlink:to="loc_us-gaap_PurchaseObligation_fc0538dd-a228-457b-a710-e3687ae9315b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:href="ntb-20201231.xsd#ntb_OtherAgreementsFiscalYearMaturityAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_86e6d157-615c-45c8-8f8c-a2f1702c9d21" xlink:to="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInNextTwelveMonths_c14571a0-74b7-420a-8d7f-6c9e59a20d38" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCommitmentDueInNextTwelveMonths"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:to="loc_us-gaap_OtherCommitmentDueInNextTwelveMonths_c14571a0-74b7-420a-8d7f-6c9e59a20d38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInSecondYear_118dd828-e1d1-4292-ba8f-1bb73da3e905" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCommitmentDueInSecondYear"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:to="loc_us-gaap_OtherCommitmentDueInSecondYear_118dd828-e1d1-4292-ba8f-1bb73da3e905" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInThirdYear_a66f18be-4e3f-49cb-bc95-9aebce92a122" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCommitmentDueInThirdYear"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:to="loc_us-gaap_OtherCommitmentDueInThirdYear_a66f18be-4e3f-49cb-bc95-9aebce92a122" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInFourthYear_c9ff0ce8-d6e6-4e07-9e91-49984a4f66a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCommitmentDueInFourthYear"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:to="loc_us-gaap_OtherCommitmentDueInFourthYear_c9ff0ce8-d6e6-4e07-9e91-49984a4f66a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInFifthYear_1e71f799-af49-4ae4-b369-719f4c8fe950" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCommitmentDueInFifthYear"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:to="loc_us-gaap_OtherCommitmentDueInFifthYear_1e71f799-af49-4ae4-b369-719f4c8fe950" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitment_e3417f91-487f-4399-806d-2a3ce4e57f89" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCommitment"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherAgreementsFiscalYearMaturityAbstract_8ab2ccef-fc9b-4b49-816b-ec54d87b2fde" xlink:to="loc_us-gaap_OtherCommitment_e3417f91-487f-4399-806d-2a3ce4e57f89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualObligationFiscalYearMaturityAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_86e6d157-615c-45c8-8f8c-a2f1702c9d21" xlink:to="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInNextTwelveMonths_bb3608f6-9731-4077-8bdc-6110db595fc0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualObligationDueInNextTwelveMonths"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:to="loc_us-gaap_ContractualObligationDueInNextTwelveMonths_bb3608f6-9731-4077-8bdc-6110db595fc0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInSecondYear_ecf1c150-b764-45c8-997a-ae11775761cd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualObligationDueInSecondYear"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:to="loc_us-gaap_ContractualObligationDueInSecondYear_ecf1c150-b764-45c8-997a-ae11775761cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInThirdYear_cdfc6de3-1049-49cd-b028-efd02413679f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualObligationDueInThirdYear"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:to="loc_us-gaap_ContractualObligationDueInThirdYear_cdfc6de3-1049-49cd-b028-efd02413679f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInFourthYear_842ced66-bd5b-457f-9058-3f83c53aa248" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualObligationDueInFourthYear"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:to="loc_us-gaap_ContractualObligationDueInFourthYear_842ced66-bd5b-457f-9058-3f83c53aa248" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInFifthYear_6d6da1ed-5a1a-4b46-b37c-81f3095c4587" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualObligationDueInFifthYear"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:to="loc_us-gaap_ContractualObligationDueInFifthYear_6d6da1ed-5a1a-4b46-b37c-81f3095c4587" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligation_2c0c72e0-8429-41e7-b72f-ed170b2797d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractualObligation"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractualObligationFiscalYearMaturityAbstract_e3a22733-9f9e-43b5-a814-205fead85dd1" xlink:to="loc_us-gaap_ContractualObligation_2c0c72e0-8429-41e7-b72f-ed170b2797d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsContractualObligationFiscalYearMaturityScheduleDetails_1" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditrelatedarrangementsrepurchaseagreementsandcommitmentsContractualObligationFiscalYearMaturityScheduleDetails_1"/>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsCreditRelatedArrangementsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditrelatedarrangementsrepurchaseagreementsandcommitmentsCreditRelatedArrangementsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsCreditRelatedArrangementsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_afe27468-cb44-43a5-9a28-3f98c7696f9e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OffsettingLiabilitiesTable_136ea629-bd6b-42f2-8ac4-7f1c2de5c8ae" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OffsettingLiabilitiesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_afe27468-cb44-43a5-9a28-3f98c7696f9e" xlink:to="loc_us-gaap_OffsettingLiabilitiesTable_136ea629-bd6b-42f2-8ac4-7f1c2de5c8ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteeObligationsByNatureAxis_e68c07af-cbc3-4842-887e-e1da5ec62834" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteeObligationsByNatureAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OffsettingLiabilitiesTable_136ea629-bd6b-42f2-8ac4-7f1c2de5c8ae" xlink:to="loc_us-gaap_GuaranteeObligationsByNatureAxis_e68c07af-cbc3-4842-887e-e1da5ec62834" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteeObligationsNatureDomain_cfe3a596-0a43-4d57-9937-95d4fa461f43" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteeObligationsNatureDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GuaranteeObligationsByNatureAxis_e68c07af-cbc3-4842-887e-e1da5ec62834" xlink:to="loc_us-gaap_GuaranteeObligationsNatureDomain_cfe3a596-0a43-4d57-9937-95d4fa461f43" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialStandbyLetterOfCreditMember_1948953f-4aa4-47c4-81b7-38f7155abb9f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialStandbyLetterOfCreditMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GuaranteeObligationsNatureDomain_cfe3a596-0a43-4d57-9937-95d4fa461f43" xlink:to="loc_us-gaap_FinancialStandbyLetterOfCreditMember_1948953f-4aa4-47c4-81b7-38f7155abb9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialGuaranteeMember_c9fb0c18-e55c-4b15-96e6-3157442a560a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialGuaranteeMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GuaranteeObligationsNatureDomain_cfe3a596-0a43-4d57-9937-95d4fa461f43" xlink:to="loc_us-gaap_FinancialGuaranteeMember_c9fb0c18-e55c-4b15-96e6-3157442a560a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_47209272-0ee1-40a4-9355-090fbe3e6f66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OffsettingLiabilitiesTable_136ea629-bd6b-42f2-8ac4-7f1c2de5c8ae" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_47209272-0ee1-40a4-9355-090fbe3e6f66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_0836ea6e-a4e2-4685-803b-2d14973c096b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_47209272-0ee1-40a4-9355-090fbe3e6f66" xlink:to="loc_us-gaap_LossContingencyNatureDomain_0836ea6e-a4e2-4685-803b-2d14973c096b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StandbyLettersOfCreditMember_1ac749e5-b115-437f-a775-c57b3b1dfb7e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StandbyLettersOfCreditMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyNatureDomain_0836ea6e-a4e2-4685-803b-2d14973c096b" xlink:to="loc_us-gaap_StandbyLettersOfCreditMember_1ac749e5-b115-437f-a775-c57b3b1dfb7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteeOfIndebtednessOfOthersMember_e0c260cd-cd6f-44d2-a2c6-cae6b025b828" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteeOfIndebtednessOfOthersMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyNatureDomain_0836ea6e-a4e2-4685-803b-2d14973c096b" xlink:to="loc_us-gaap_GuaranteeOfIndebtednessOfOthersMember_e0c260cd-cd6f-44d2-a2c6-cae6b025b828" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OffsettingLiabilitiesLineItems_9d542391-959f-462a-be24-b9324127654f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OffsettingLiabilitiesLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OffsettingLiabilitiesTable_136ea629-bd6b-42f2-8ac4-7f1c2de5c8ae" xlink:to="loc_us-gaap_OffsettingLiabilitiesLineItems_9d542391-959f-462a-be24-b9324127654f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_GuarantorObligationsTermPeriod_4df6869f-be28-4f47-8d26-0ddb89dfb68b" xlink:href="ntb-20201231.xsd#ntb_GuarantorObligationsTermPeriod"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OffsettingLiabilitiesLineItems_9d542391-959f-462a-be24-b9324127654f" xlink:to="loc_ntb_GuarantorObligationsTermPeriod_4df6869f-be28-4f47-8d26-0ddb89dfb68b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteeObligationsCurrentCarryingValue_00563486-2628-4956-89d0-841321732491" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteeObligationsCurrentCarryingValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OffsettingLiabilitiesLineItems_9d542391-959f-462a-be24-b9324127654f" xlink:to="loc_us-gaap_GuaranteeObligationsCurrentCarryingValue_00563486-2628-4956-89d0-841321732491" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_GuaranteeObligationsCollateralAmount_15d7e916-ed93-4831-a180-34325f2db9bf" xlink:href="ntb-20201231.xsd#ntb_GuaranteeObligationsCollateralAmount"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OffsettingLiabilitiesLineItems_9d542391-959f-462a-be24-b9324127654f" xlink:to="loc_ntb_GuaranteeObligationsCollateralAmount_15d7e916-ed93-4831-a180-34325f2db9bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_GuaranteeObligationsNetValue_05609471-3b23-4003-851c-e24e324ff3af" xlink:href="ntb-20201231.xsd#ntb_GuaranteeObligationsNetValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OffsettingLiabilitiesLineItems_9d542391-959f-462a-be24-b9324127654f" xlink:to="loc_ntb_GuaranteeObligationsNetValue_05609471-3b23-4003-851c-e24e324ff3af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsRepurchaseAgreementsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditrelatedarrangementsrepurchaseagreementsandcommitmentsRepurchaseAgreementsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsRepurchaseAgreementsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_27f859c6-cef7-4bba-afe7-8c993823cb80" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesTable_6053e8e2-4841-4bab-abd4-cd70f14b03ad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_27f859c6-cef7-4bba-afe7-8c993823cb80" xlink:to="loc_us-gaap_LossContingenciesTable_6053e8e2-4841-4bab-abd4-cd70f14b03ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_36b9e300-eb72-44b5-a970-8571f54bd189" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_6053e8e2-4841-4bab-abd4-cd70f14b03ad" xlink:to="loc_us-gaap_FinancialInstrumentAxis_36b9e300-eb72-44b5-a970-8571f54bd189" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_772145b2-275c-4ee3-95ef-86fdd437b349" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_36b9e300-eb72-44b5-a970-8571f54bd189" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_772145b2-275c-4ee3-95ef-86fdd437b349" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MortgageBackedSecuritiesIssuedByUSGovernmentSponsoredEnterprisesMember_e38ec667-9819-4d80-803d-98056b33235b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MortgageBackedSecuritiesIssuedByUSGovernmentSponsoredEnterprisesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_772145b2-275c-4ee3-95ef-86fdd437b349" xlink:to="loc_us-gaap_MortgageBackedSecuritiesIssuedByUSGovernmentSponsoredEnterprisesMember_e38ec667-9819-4d80-803d-98056b33235b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesLineItems_9adf8551-61c2-4562-a764-5100f90f38de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_6053e8e2-4841-4bab-abd4-cd70f14b03ad" xlink:to="loc_us-gaap_LossContingenciesLineItems_9adf8551-61c2-4562-a764-5100f90f38de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ResellAgreementsNumberofOpenPositions_3838a0c0-41e1-4c16-bd50-07c4d4414dbe" xlink:href="ntb-20201231.xsd#ntb_ResellAgreementsNumberofOpenPositions"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_9adf8551-61c2-4562-a764-5100f90f38de" xlink:to="loc_ntb_ResellAgreementsNumberofOpenPositions_3838a0c0-41e1-4c16-bd50-07c4d4414dbe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ResellAgreementsMaturityPeriod_dfdeabe7-118c-47c9-8744-793cb59f25f5" xlink:href="ntb-20201231.xsd#ntb_ResellAgreementsMaturityPeriod"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_9adf8551-61c2-4562-a764-5100f90f38de" xlink:to="loc_ntb_ResellAgreementsMaturityPeriod_dfdeabe7-118c-47c9-8744-793cb59f25f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuritiesPurchasedUnderAgreementsToResell_39ea03e3-4be1-4caf-a197-50b8004451db" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SecuritiesPurchasedUnderAgreementsToResell"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_9adf8551-61c2-4562-a764-5100f90f38de" xlink:to="loc_us-gaap_SecuritiesPurchasedUnderAgreementsToResell_39ea03e3-4be1-4caf-a197-50b8004451db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsLegalProceedingsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CreditrelatedarrangementsrepurchaseagreementsandcommitmentsLegalProceedingsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CreditrelatedarrangementsrepurchaseagreementsandcommitmentsLegalProceedingsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_7873ee73-301a-4e01-b5d7-aec96d0b0b4b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesTable_185b04bc-3bd0-4911-b0f2-768a85ad9e1d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_7873ee73-301a-4e01-b5d7-aec96d0b0b4b" xlink:to="loc_us-gaap_LossContingenciesTable_185b04bc-3bd0-4911-b0f2-768a85ad9e1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseAxis_e7be1cfa-4d1f-42ca-aa12-bab507e17c19" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_185b04bc-3bd0-4911-b0f2-768a85ad9e1d" xlink:to="loc_srt_LitigationCaseAxis_e7be1cfa-4d1f-42ca-aa12-bab507e17c19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain_979a5f4b-6c32-4309-9ff8-3d7b85b25b79" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_e7be1cfa-4d1f-42ca-aa12-bab507e17c19" xlink:to="loc_srt_LitigationCaseTypeDomain_979a5f4b-6c32-4309-9ff8-3d7b85b25b79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_JohnDoeSummonsesMember_cfcb09fd-87b1-4a9a-9392-fce1138a0ad4" xlink:href="ntb-20201231.xsd#ntb_JohnDoeSummonsesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_979a5f4b-6c32-4309-9ff8-3d7b85b25b79" xlink:to="loc_ntb_JohnDoeSummonsesMember_cfcb09fd-87b1-4a9a-9392-fce1138a0ad4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationStatusAxis_19dfc89e-2a9f-480c-b9ed-f3dc4c8e9230" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LitigationStatusAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_185b04bc-3bd0-4911-b0f2-768a85ad9e1d" xlink:to="loc_us-gaap_LitigationStatusAxis_19dfc89e-2a9f-480c-b9ed-f3dc4c8e9230" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationStatusDomain_da635cac-c5af-404b-9663-7152cb3f062b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LitigationStatusDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationStatusAxis_19dfc89e-2a9f-480c-b9ed-f3dc4c8e9230" xlink:to="loc_us-gaap_LitigationStatusDomain_da635cac-c5af-404b-9663-7152cb3f062b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PendingLitigationMember_65a94530-815c-42cd-be3d-5b577c12a0f1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PendingLitigationMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationStatusDomain_da635cac-c5af-404b-9663-7152cb3f062b" xlink:to="loc_us-gaap_PendingLitigationMember_65a94530-815c-42cd-be3d-5b577c12a0f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesLineItems_7eabe819-cf1c-4b43-9dff-669a6f3759b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_185b04bc-3bd0-4911-b0f2-768a85ad9e1d" xlink:to="loc_us-gaap_LossContingenciesLineItems_7eabe819-cf1c-4b43-9dff-669a6f3759b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNumberOfDefendants_26a58c87-6638-4c8e-aa94-849d39d0e049" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNumberOfDefendants"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_7eabe819-cf1c-4b43-9dff-669a6f3759b8" xlink:to="loc_us-gaap_LossContingencyNumberOfDefendants_26a58c87-6638-4c8e-aa94-849d39d0e049" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyAccrualProvision_6b9bbb22-cc2e-49ea-be0f-9ef42112dc9f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyAccrualProvision"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_7eabe819-cf1c-4b43-9dff-669a6f3759b8" xlink:to="loc_us-gaap_LossContingencyAccrualProvision_6b9bbb22-cc2e-49ea-be0f-9ef42112dc9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Leases" xlink:type="simple" xlink:href="ntb-20201231.xsd#Leases"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Leases" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_845700ef-e52b-402d-b564-7ea45cdfe7de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasesOfLessorDisclosureTextBlock_99ffc711-7fca-4106-9b10-23e009e8fec6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeasesOfLessorDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_845700ef-e52b-402d-b564-7ea45cdfe7de" xlink:to="loc_us-gaap_OperatingLeasesOfLessorDisclosureTextBlock_99ffc711-7fca-4106-9b10-23e009e8fec6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_8cafb190-30d1-4aaf-bc7d-d7fdb9f5b433" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeasesTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_845700ef-e52b-402d-b564-7ea45cdfe7de" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_8cafb190-30d1-4aaf-bc7d-d7fdb9f5b433" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LeasesTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#LeasesTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LeasesTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_5e1a588c-1c99-4967-9b51-ac3f2b8e18ff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCostTableTextBlock_f4d10715-560d-4c0d-bfc3-76b2b8983c35" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeaseCostTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5e1a588c-1c99-4967-9b51-ac3f2b8e18ff" xlink:to="loc_us-gaap_LeaseCostTableTextBlock_f4d10715-560d-4c0d-bfc3-76b2b8983c35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_f5ae174e-a786-471c-b8f4-2a314601c845" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5e1a588c-1c99-4967-9b51-ac3f2b8e18ff" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_f5ae174e-a786-471c-b8f4-2a314601c845" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LeasesNarrativeDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LeasesNarrativeDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LeasesNarrativeDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_a30353fb-3bbb-41d0-8a5e-2a652df2992d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseAndRentalExpense_fdb5a615-29ae-41fa-be14-7fd6ccdc6b2b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeaseAndRentalExpense"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_a30353fb-3bbb-41d0-8a5e-2a652df2992d" xlink:to="loc_us-gaap_LeaseAndRentalExpense_fdb5a615-29ae-41fa-be14-7fd6ccdc6b2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LeasesSummaryofLeaseCostsandLesseeOperatingLeaseLiabilityMaturityDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LeasesSummaryofLeaseCostsandLesseeOperatingLeaseLiabilityMaturityDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LeasesSummaryofLeaseCostsandLesseeOperatingLeaseLiabilityMaturityDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCostAbstract_788a827d-e254-4bc0-bb30-a3332615e8f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeaseCostAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_LeaseCostAbstract_788a827d-e254-4bc0-bb30-a3332615e8f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_0bca1e8e-b9c1-4c67-823f-d550f2518447" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseCost"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseCostAbstract_788a827d-e254-4bc0-bb30-a3332615e8f9" xlink:to="loc_us-gaap_OperatingLeaseCost_0bca1e8e-b9c1-4c67-823f-d550f2518447" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermLeaseCost_25fc81f7-2eca-4ad4-9615-fd5aad001162" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermLeaseCost"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseCostAbstract_788a827d-e254-4bc0-bb30-a3332615e8f9" xlink:to="loc_us-gaap_ShortTermLeaseCost_25fc81f7-2eca-4ad4-9615-fd5aad001162" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubleaseIncome_44b80701-fd9a-4da5-81bb-3037793bb5c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubleaseIncome"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseCostAbstract_788a827d-e254-4bc0-bb30-a3332615e8f9" xlink:to="loc_us-gaap_SubleaseIncome_44b80701-fd9a-4da5-81bb-3037793bb5c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCost_e8778bcc-3117-4143-9147-f6442bae2046" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeaseCost"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseCostAbstract_788a827d-e254-4bc0-bb30-a3332615e8f9" xlink:to="loc_us-gaap_LeaseCost_e8778bcc-3117-4143-9147-f6442bae2046" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLeaseIncome_80900759-7bf4-4bbb-be36-8b052e349976" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLeaseIncome"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseCostAbstract_788a827d-e254-4bc0-bb30-a3332615e8f9" xlink:to="loc_us-gaap_OperatingLeaseLeaseIncome_80900759-7bf4-4bbb-be36-8b052e349976" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_11a2db31-4434-4203-82d0-0b9910b30f3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_11a2db31-4434-4203-82d0-0b9910b30f3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasePayments_435606a9-afa8-4b42-8900-ef310cfe97a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeasePayments"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeasePayments_435606a9-afa8-4b42-8900-ef310cfe97a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_e9b44511-3739-47b3-bfcb-0b0528822f57" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_e9b44511-3739-47b3-bfcb-0b0528822f57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_5364f6a2-4427-44cf-aa6c-1a7829cca820" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_5364f6a2-4427-44cf-aa6c-1a7829cca820" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityStatementOfFinancialPositionExtensibleList_9d54b564-728a-4cf7-b8ff-45f8a884fe86" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityStatementOfFinancialPositionExtensibleList"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeaseLiabilityStatementOfFinancialPositionExtensibleList_9d54b564-728a-4cf7-b8ff-45f8a884fe86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_a10ac0dd-c688-4769-9cd4-5fea99fb8049" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiability"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeaseLiability_a10ac0dd-c688-4769-9cd4-5fea99fb8049" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_384454d3-1ce5-43a6-9ee3-8e1743ef919f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_384454d3-1ce5-43a6-9ee3-8e1743ef919f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_46079f3d-3ee5-498a-8fda-9c234a4c2c8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_46079f3d-3ee5-498a-8fda-9c234a4c2c8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_30514ed3-70ad-4b73-914a-16acbc18d38f" xlink:to="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_a03b1861-b71b-4e40-84a7-f316fce3a534" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_a03b1861-b71b-4e40-84a7-f316fce3a534" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_d4fe6e56-4298-4ec8-9514-de9c2adf14a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_d4fe6e56-4298-4ec8-9514-de9c2adf14a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_544c84a0-a1ab-40b5-9548-d16704fcf807" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_544c84a0-a1ab-40b5-9548-d16704fcf807" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_2f52a768-210d-481a-9ea3-1b3138dc940e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_2f52a768-210d-481a-9ea3-1b3138dc940e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_5d68d8cc-01ba-41cc-8e7d-277bd181daf6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_5d68d8cc-01ba-41cc-8e7d-277bd181daf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_39f1dc05-dfe8-409e-9120-3e0151fce0b5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_39f1dc05-dfe8-409e-9120-3e0151fce0b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_f0f04b9e-8fae-4593-a557-ed98bb93885d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_f0f04b9e-8fae-4593-a557-ed98bb93885d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_7f6b6aec-0f18-449c-af40-3de19d33beee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_7f6b6aec-0f18-449c-af40-3de19d33beee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_bcf41e75-4f6d-4f86-9467-755752579534" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiability"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_cc63cd99-ce0a-4800-830d-180700a9d2f0" xlink:to="loc_us-gaap_OperatingLeaseLiability_bcf41e75-4f6d-4f86-9467-755752579534" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LeasesSummaryofLeaseCostsandLesseeOperatingLeaseLiabilityMaturityDetails_1" xlink:type="simple" xlink:href="ntb-20201231.xsd#LeasesSummaryofLeaseCostsandLesseeOperatingLeaseLiabilityMaturityDetails_1"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LeasesSummaryofLeaseCostsandLesseeOperatingLeaseLiabilityMaturityDetails_1" xlink:type="extended"/>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Loaninterestincome" xlink:type="simple" xlink:href="ntb-20201231.xsd#Loaninterestincome"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Loaninterestincome" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncomeAndExpensesAbstract_5ed1fe17-2c5e-41cb-8fb0-7f2903f21e43" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherIncomeAndExpensesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndOtherIncomeTextBlock_def012c2-28cf-4bb1-8647-d35e3aaceaa9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndOtherIncomeTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_5ed1fe17-2c5e-41cb-8fb0-7f2903f21e43" xlink:to="loc_us-gaap_InterestAndOtherIncomeTextBlock_def012c2-28cf-4bb1-8647-d35e3aaceaa9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoaninterestincomeTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoaninterestincomeTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoaninterestincomeTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncomeAndExpensesAbstract_6cbdc06a-2f20-4710-8a40-3a45fec8a179" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherIncomeAndExpensesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndOtherIncomeTableTextBlock_2431de56-a6c2-486d-8555-84ffa4c3ad59" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndOtherIncomeTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_6cbdc06a-2f20-4710-8a40-3a45fec8a179" xlink:to="loc_us-gaap_InterestAndOtherIncomeTableTextBlock_2431de56-a6c2-486d-8555-84ffa4c3ad59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LoaninterestincomeDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LoaninterestincomeDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LoaninterestincomeDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncomeAndExpensesAbstract_21d9d68a-4727-40a5-8bab-97711e9d3512" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherIncomeAndExpensesAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansAndLeasesHeldInPortfolio_733368ac-0da7-4273-9096-8656704ea052" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndFeeIncomeLoansAndLeasesHeldInPortfolio"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_21d9d68a-4727-40a5-8bab-97711e9d3512" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansAndLeasesHeldInPortfolio_733368ac-0da7-4273-9096-8656704ea052" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentForAmortizationAbstract_50d1f493-2c32-4e1e-835d-bf13d610ea4c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentForAmortizationAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_21d9d68a-4727-40a5-8bab-97711e9d3512" xlink:to="loc_us-gaap_AdjustmentForAmortizationAbstract_50d1f493-2c32-4e1e-835d-bf13d610ea4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfDeferredHedgeGains_5774598f-f999-4cea-94f7-c103cad25f75" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfDeferredHedgeGains"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentForAmortizationAbstract_50d1f493-2c32-4e1e-835d-bf13d610ea4c" xlink:to="loc_us-gaap_AmortizationOfDeferredHedgeGains_5774598f-f999-4cea-94f7-c103cad25f75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfDeferredLoanOriginationFeesNet_dcaf768b-c4e6-4417-ab12-486f6baa8d6c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfDeferredLoanOriginationFeesNet"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentForAmortizationAbstract_50d1f493-2c32-4e1e-835d-bf13d610ea4c" xlink:to="loc_us-gaap_AmortizationOfDeferredLoanOriginationFeesNet_dcaf768b-c4e6-4417-ab12-486f6baa8d6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AmortizationOfFairValueAdjustmentOnPurchasedLoans_1528cee4-61f8-4ccd-8b65-538e15bd2700" xlink:href="ntb-20201231.xsd#ntb_AmortizationOfFairValueAdjustmentOnPurchasedLoans"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentForAmortizationAbstract_50d1f493-2c32-4e1e-835d-bf13d610ea4c" xlink:to="loc_ntb_AmortizationOfFairValueAdjustmentOnPurchasedLoans_1528cee4-61f8-4ccd-8b65-538e15bd2700" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_2042e4fe-738b-40b5-9986-b476eba9224f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndFeeIncomeLoansAndLeases"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_21d9d68a-4727-40a5-8bab-97711e9d3512" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_2042e4fe-738b-40b5-9986-b476eba9224f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueHedgeLiabilitiesAtFairValue_9f39cc91-2261-4a01-b9c3-642cbce33de2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueHedgeLiabilitiesAtFairValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_21d9d68a-4727-40a5-8bab-97711e9d3512" xlink:to="loc_us-gaap_FairValueHedgeLiabilitiesAtFairValue_9f39cc91-2261-4a01-b9c3-642cbce33de2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums_264679bb-8346-4379-96cf-71499c6b601b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_21d9d68a-4727-40a5-8bab-97711e9d3512" xlink:to="loc_us-gaap_UnamortizedLoanCommitmentAndOriginationFeesAndUnamortizedDiscountsOrPremiums_264679bb-8346-4379-96cf-71499c6b601b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Segmentedinformation" xlink:type="simple" xlink:href="ntb-20201231.xsd#Segmentedinformation"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Segmentedinformation" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_a71ab830-bc4c-4938-8d8b-bc7bed9dc58e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingDisclosureTextBlock_76eeeb58-f556-415a-b1bf-c16e39408782" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_a71ab830-bc4c-4938-8d8b-bc7bed9dc58e" xlink:to="loc_us-gaap_SegmentReportingDisclosureTextBlock_76eeeb58-f556-415a-b1bf-c16e39408782" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SegmentedinformationTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#SegmentedinformationTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SegmentedinformationTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_35f9454d-9356-4aa6-ab38-8058a0afd575" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_b2cec16a-c521-4417-91ae-e1e5df2d3c49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_35f9454d-9356-4aa6-ab38-8058a0afd575" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_b2cec16a-c521-4417-91ae-e1e5df2d3c49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SegmentedinformationDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SegmentedinformationDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SegmentedinformationDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_4190290d-ba4b-471b-83c6-b1889c9ed7c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfReportableSegments_e82e8f14-76e6-4cb2-bdfc-a06b46e44cc9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NumberOfReportableSegments"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_4190290d-ba4b-471b-83c6-b1889c9ed7c0" xlink:to="loc_us-gaap_NumberOfReportableSegments_e82e8f14-76e6-4cb2-bdfc-a06b46e44cc9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_59da4370-0c13-481f-8929-8e8b2ad69fb3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_4190290d-ba4b-471b-83c6-b1889c9ed7c0" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_59da4370-0c13-481f-8929-8e8b2ad69fb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsAxis_b4ed7292-c4a3-47b4-836c-4b1c52d695da" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_59da4370-0c13-481f-8929-8e8b2ad69fb3" xlink:to="loc_srt_ConsolidationItemsAxis_b4ed7292-c4a3-47b4-836c-4b1c52d695da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsDomain_4cc7819f-24ac-43b4-a4a9-7d921a802641" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsAxis_b4ed7292-c4a3-47b4-836c-4b1c52d695da" xlink:to="loc_srt_ConsolidationItemsDomain_4cc7819f-24ac-43b4-a4a9-7d921a802641" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingSegmentsMember_72cd32ae-2505-4ea7-ba49-8eb3649e9401" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingSegmentsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsDomain_4cc7819f-24ac-43b4-a4a9-7d921a802641" xlink:to="loc_us-gaap_OperatingSegmentsMember_72cd32ae-2505-4ea7-ba49-8eb3649e9401" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntersegmentEliminationMember_7caf23b9-c8e7-48e6-98e2-c379f10fa38e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntersegmentEliminationMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsDomain_4cc7819f-24ac-43b4-a4a9-7d921a802641" xlink:to="loc_us-gaap_IntersegmentEliminationMember_7caf23b9-c8e7-48e6-98e2-c379f10fa38e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_1db2739f-1c50-43d1-8e18-838181c3edb8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_59da4370-0c13-481f-8929-8e8b2ad69fb3" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_1db2739f-1c50-43d1-8e18-838181c3edb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_4b184cb8-1a0b-4f5f-b60c-1c4dfe4c28ab" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_1db2739f-1c50-43d1-8e18-838181c3edb8" xlink:to="loc_us-gaap_SegmentDomain_4b184cb8-1a0b-4f5f-b60c-1c4dfe4c28ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BermudaSegmentMember_1a62b4b9-f6b4-4dba-b84a-77ab66a5203c" xlink:href="ntb-20201231.xsd#ntb_BermudaSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_4b184cb8-1a0b-4f5f-b60c-1c4dfe4c28ab" xlink:to="loc_ntb_BermudaSegmentMember_1a62b4b9-f6b4-4dba-b84a-77ab66a5203c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CaymanSegmentMember_25661c87-720a-4fac-9e15-302f3b742b7d" xlink:href="ntb-20201231.xsd#ntb_CaymanSegmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_4b184cb8-1a0b-4f5f-b60c-1c4dfe4c28ab" xlink:to="loc_ntb_CaymanSegmentMember_25661c87-720a-4fac-9e15-302f3b742b7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_41054322-4aa5-43b9-b247-8fa3f2086b59" xlink:href="ntb-20201231.xsd#ntb_ChannelIslandsAndUnitedKingdomSegmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_4b184cb8-1a0b-4f5f-b60c-1c4dfe4c28ab" xlink:to="loc_ntb_ChannelIslandsAndUnitedKingdomSegmentMember_41054322-4aa5-43b9-b247-8fa3f2086b59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllOtherSegmentsMember_90c18cc1-31ce-427b-b021-114e40529152" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllOtherSegmentsMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_4b184cb8-1a0b-4f5f-b60c-1c4dfe4c28ab" xlink:to="loc_us-gaap_AllOtherSegmentsMember_90c18cc1-31ce-427b-b021-114e40529152" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsegmentsAxis_e9cb1f60-dc80-421a-aca1-eec6bc4b0944" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_59da4370-0c13-481f-8929-8e8b2ad69fb3" xlink:to="loc_us-gaap_SubsegmentsAxis_e9cb1f60-dc80-421a-aca1-eec6bc4b0944" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsegmentsDomain_c95cbe03-810c-45da-875d-032b57019721" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsegmentsAxis_e9cb1f60-dc80-421a-aca1-eec6bc4b0944" xlink:to="loc_us-gaap_SubsegmentsDomain_c95cbe03-810c-45da-875d-032b57019721" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CustomerSubsegmentMember_df8c49c5-2b86-4462-97bb-4d51d0514268" xlink:href="ntb-20201231.xsd#ntb_CustomerSubsegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsegmentsDomain_c95cbe03-810c-45da-875d-032b57019721" xlink:to="loc_ntb_CustomerSubsegmentMember_df8c49c5-2b86-4462-97bb-4d51d0514268" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsegmentsConsolidationItemsAxis_4518db91-a81b-49a9-8397-c72e4ed02583" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_59da4370-0c13-481f-8929-8e8b2ad69fb3" xlink:to="loc_us-gaap_SubsegmentsConsolidationItemsAxis_4518db91-a81b-49a9-8397-c72e4ed02583" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsegmentsConsolidationItemsDomain_bc4b3f21-d4b0-420a-88c4-06580a24d00f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsegmentsConsolidationItemsAxis_4518db91-a81b-49a9-8397-c72e4ed02583" xlink:to="loc_us-gaap_SubsegmentsConsolidationItemsDomain_bc4b3f21-d4b0-420a-88c4-06580a24d00f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReportableSubsegmentsMember_1747de35-2c04-4490-8994-1d62a00a3f11" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReportableSubsegmentsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsegmentsConsolidationItemsDomain_bc4b3f21-d4b0-420a-88c4-06580a24d00f" xlink:to="loc_us-gaap_ReportableSubsegmentsMember_1747de35-2c04-4490-8994-1d62a00a3f11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntersubsegmentEliminationsMember_09815662-aab7-4863-af17-ba4b28afbe33" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntersubsegmentEliminationsMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsegmentsConsolidationItemsDomain_bc4b3f21-d4b0-420a-88c4-06580a24d00f" xlink:to="loc_us-gaap_IntersubsegmentEliminationsMember_09815662-aab7-4863-af17-ba4b28afbe33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingInformationLineItems"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_59da4370-0c13-481f-8929-8e8b2ad69fb3" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NumberofBranchLocations_e8762114-a394-4efc-96cf-bca45454d401" xlink:href="ntb-20201231.xsd#ntb_NumberofBranchLocations"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_ntb_NumberofBranchLocations_e8762114-a394-4efc-96cf-bca45454d401" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_73cc9ff5-2a01-48b0-88dc-eaa87bde71c2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_us-gaap_Assets_73cc9ff5-2a01-48b0-88dc-eaa87bde71c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_51c91ecd-d943-401a-8867-1a4a1105a90b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseNet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_51c91ecd-d943-401a-8867-1a4a1105a90b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLossesExpensed_8405a5b8-0a9f-44d3-9d60-fd520c359f6c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForLoanLossesExpensed"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_us-gaap_ProvisionForLoanLossesExpensed_8405a5b8-0a9f-44d3-9d60-fd520c359f6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther_1b05c3ec-a0d2-428b-a4d2-ad9ee3f37e4f" xlink:href="ntb-20201231.xsd#ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther_1b05c3ec-a0d2-428b-a4d2-ad9ee3f37e4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_RevenuesBeforeGainsLosses_9efa291b-2ff6-4b9d-8ba6-f983f2a8785a" xlink:href="ntb-20201231.xsd#ntb_RevenuesBeforeGainsLosses"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_ntb_RevenuesBeforeGainsLosses_9efa291b-2ff6-4b9d-8ba6-f983f2a8785a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss_fda9dc41-d7f5-4323-abec-b47668652a1e" xlink:href="ntb-20201231.xsd#ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss_fda9dc41-d7f5-4323-abec-b47668652a1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_914c109e-648b-431a-919d-47efff775423" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Revenues"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_us-gaap_Revenues_914c109e-648b-431a-919d-47efff775423" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NonInterestExpenseIncludingIncomeTaxExpense_4cbf853e-fe1c-4d65-8fe6-11077f87f7b4" xlink:href="ntb-20201231.xsd#ntb_NonInterestExpenseIncludingIncomeTaxExpense"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_ntb_NonInterestExpenseIncludingIncomeTaxExpense_4cbf853e-fe1c-4d65-8fe6-11077f87f7b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_8b7d724e-efff-427e-9252-b9db19877577" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_85fbb60d-ba16-443e-8eb8-edc350412b3d" xlink:to="loc_us-gaap_NetIncomeLoss_8b7d724e-efff-427e-9252-b9db19877577" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Derivativeinstrumentsandriskmanagement" xlink:type="simple" xlink:href="ntb-20201231.xsd#Derivativeinstrumentsandriskmanagement"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Derivativeinstrumentsandriskmanagement" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_ef0a575c-d0ec-4ea1-bd14-4e1f46c1a716" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_90619bb6-3bda-4a20-91d5-8ffe7ffdf410" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_ef0a575c-d0ec-4ea1-bd14-4e1f46c1a716" xlink:to="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_90619bb6-3bda-4a20-91d5-8ffe7ffdf410" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#DerivativeinstrumentsandriskmanagementTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_5fa12df4-254a-4b68-8593-7f7f5fea848f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDerivativeInstrumentsTextBlock_fe7482ae-aef4-4a98-b6c8-8ce84dfd9b3d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDerivativeInstrumentsTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_5fa12df4-254a-4b68-8593-7f7f5fea848f" xlink:to="loc_us-gaap_ScheduleOfDerivativeInstrumentsTextBlock_fe7482ae-aef4-4a98-b6c8-8ce84dfd9b3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OffsettingAssetsTableTextBlock_f8f1cdf1-a4ce-4d7f-a95d-8d6bca19b01c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OffsettingAssetsTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_5fa12df4-254a-4b68-8593-7f7f5fea848f" xlink:to="loc_us-gaap_OffsettingAssetsTableTextBlock_f8f1cdf1-a4ce-4d7f-a95d-8d6bca19b01c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OffsettingLiabilitiesTableTextBlock_ad342892-d053-4d69-a9f3-5c2533f6538e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OffsettingLiabilitiesTableTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_5fa12df4-254a-4b68-8593-7f7f5fea848f" xlink:to="loc_us-gaap_OffsettingLiabilitiesTableTextBlock_ad342892-d053-4d69-a9f3-5c2533f6538e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDerivativeInstrumentsGainLossInStatementOfFinancialPerformanceTextBlock_f5de5cb1-e37d-4890-8708-16938a008410" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDerivativeInstrumentsGainLossInStatementOfFinancialPerformanceTextBlock"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_5fa12df4-254a-4b68-8593-7f7f5fea848f" xlink:to="loc_us-gaap_ScheduleOfDerivativeInstrumentsGainLossInStatementOfFinancialPerformanceTextBlock_f5de5cb1-e37d-4890-8708-16938a008410" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementScheduleofNotionalAmountsandRelatedFairValueMeasurementsofDerivativeInstrumentsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#DerivativeinstrumentsandriskmanagementScheduleofNotionalAmountsandRelatedFairValueMeasurementsofDerivativeInstrumentsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementScheduleofNotionalAmountsandRelatedFairValueMeasurementsofDerivativeInstrumentsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_ee6dcd25-3dea-4601-ab5b-8c7b94b5be1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_1bf9fe22-f536-42f6-83d5-c3913462f2be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_ee6dcd25-3dea-4601-ab5b-8c7b94b5be1a" xlink:to="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_1bf9fe22-f536-42f6-83d5-c3913462f2be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_ace683e7-7c5d-4177-a0aa-2df6b603e300" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_1bf9fe22-f536-42f6-83d5-c3913462f2be" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_ace683e7-7c5d-4177-a0aa-2df6b603e300" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_9f855b0f-c80e-4a72-a5d5-0f20de2678d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_ace683e7-7c5d-4177-a0aa-2df6b603e300" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_9f855b0f-c80e-4a72-a5d5-0f20de2678d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrencySwapMember_6043e8e5-8129-40e6-95c5-95f062a79e1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CurrencySwapMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_9f855b0f-c80e-4a72-a5d5-0f20de2678d3" xlink:to="loc_us-gaap_CurrencySwapMember_6043e8e5-8129-40e6-95c5-95f062a79e1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_RiskManagementDerivativesMember_75fe6a55-7889-49b7-aa93-6d156f967f42" xlink:href="ntb-20201231.xsd#ntb_RiskManagementDerivativesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_9f855b0f-c80e-4a72-a5d5-0f20de2678d3" xlink:to="loc_ntb_RiskManagementDerivativesMember_75fe6a55-7889-49b7-aa93-6d156f967f42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SpotandForwardForeignExchangeMember_78c3f14c-93bb-4aa8-af78-f1571ab70ec9" xlink:href="ntb-20201231.xsd#ntb_SpotandForwardForeignExchangeMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_9f855b0f-c80e-4a72-a5d5-0f20de2678d3" xlink:to="loc_ntb_SpotandForwardForeignExchangeMember_78c3f14c-93bb-4aa8-af78-f1571ab70ec9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_200bded4-f1cc-4750-9be2-5a2041f3fb2a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_9f855b0f-c80e-4a72-a5d5-0f20de2678d3" xlink:to="loc_us-gaap_ForeignExchangeContractMember_200bded4-f1cc-4750-9be2-5a2041f3fb2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_da4e7511-2502-4290-b352-a611ced8df92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_1bf9fe22-f536-42f6-83d5-c3913462f2be" xlink:to="loc_us-gaap_HedgingDesignationAxis_da4e7511-2502-4290-b352-a611ced8df92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_5bba6a4d-4db1-47ba-8f38-f5d529603f3a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationAxis_da4e7511-2502-4290-b352-a611ced8df92" xlink:to="loc_us-gaap_HedgingDesignationDomain_5bba6a4d-4db1-47ba-8f38-f5d529603f3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_b74f0d60-a7ba-419a-89d8-ceb82e52d273" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_5bba6a4d-4db1-47ba-8f38-f5d529603f3a" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_b74f0d60-a7ba-419a-89d8-ceb82e52d273" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_38625d81-4beb-4ab5-8cca-7e893add7008" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NondesignatedMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_5bba6a4d-4db1-47ba-8f38-f5d529603f3a" xlink:to="loc_us-gaap_NondesignatedMember_38625d81-4beb-4ab5-8cca-7e893add7008" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d60eb9df-6b23-4cc5-bdfa-7bf7024b82b3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_1bf9fe22-f536-42f6-83d5-c3913462f2be" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d60eb9df-6b23-4cc5-bdfa-7bf7024b82b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_a6abb11b-561b-4a74-ae92-84c4537ed86d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_d60eb9df-6b23-4cc5-bdfa-7bf7024b82b3" xlink:to="loc_us-gaap_HedgingRelationshipDomain_a6abb11b-561b-4a74-ae92-84c4537ed86d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetInvestmentHedgingMember_0333cc80-f5b0-4154-9fd4-ec05bc61cb03" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetInvestmentHedgingMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingRelationshipDomain_a6abb11b-561b-4a74-ae92-84c4537ed86d" xlink:to="loc_us-gaap_NetInvestmentHedgingMember_0333cc80-f5b0-4154-9fd4-ec05bc61cb03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueHedgingMember_8f6adab0-7404-4f73-a85a-5ceb3a959d9a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueHedgingMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingRelationshipDomain_a6abb11b-561b-4a74-ae92-84c4537ed86d" xlink:to="loc_us-gaap_FairValueHedgingMember_8f6adab0-7404-4f73-a85a-5ceb3a959d9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativesFairValueLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_1bf9fe22-f536-42f6-83d5-c3913462f2be" xlink:to="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNumberOfInstrumentsHeld_420e5a90-df88-46a9-9881-829f0678ec7d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeNumberOfInstrumentsHeld"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:to="loc_us-gaap_DerivativeNumberOfInstrumentsHeld_420e5a90-df88-46a9-9881-829f0678ec7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetNotionalAmount_4f781965-7814-4aad-897c-ed31509416a2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssetNotionalAmount"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:to="loc_us-gaap_DerivativeAssetNotionalAmount_4f781965-7814-4aad-897c-ed31509416a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4633f304-7250-4240-89b5-379c9f616530" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4633f304-7250-4240-89b5-379c9f616530" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_03472750-a3bb-48c3-9a34-79152cc76f63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_03472750-a3bb-48c3-9a34-79152cc76f63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet_d48b022e-1b98-4ffc-a684-3d0c235152f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:to="loc_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet_d48b022e-1b98-4ffc-a684-3d0c235152f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsForeign_4f22f70f-6f3a-449d-959c-cfba5317ccf8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsForeign"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_0f2755b3-8873-49d1-8955-8bc0a4d42f21" xlink:to="loc_us-gaap_DepositsForeign_4f22f70f-6f3a-449d-959c-cfba5317ccf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementOffsettingDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#DerivativeinstrumentsandriskmanagementOffsettingDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementOffsettingDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_709e5441-e0ac-4a1a-a4d4-99a213725eca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssetsAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_709e5441-e0ac-4a1a-a4d4-99a213725eca" xlink:to="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4f89a975-d350-40fc-8956-e08f0194cfd3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_4f89a975-d350-40fc-8956-e08f0194cfd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetFairValueGrossLiability_63b05291-dcbb-4e16-b478-05e835791ab3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssetFairValueGrossLiability"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:to="loc_us-gaap_DerivativeAssetFairValueGrossLiability_63b05291-dcbb-4e16-b478-05e835791ab3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_e49223e7-2ac2-4338-8e2e-feb2bf4aaefc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssets"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:to="loc_us-gaap_DerivativeAssets_e49223e7-2ac2-4338-8e2e-feb2bf4aaefc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetNotOffsetPolicyElectionDeduction_f448e5c6-5108-470d-813d-b148decb3844" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssetNotOffsetPolicyElectionDeduction"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:to="loc_us-gaap_DerivativeAssetNotOffsetPolicyElectionDeduction_f448e5c6-5108-470d-813d-b148decb3844" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeCollateralObligationToReturnCash_97774407-a280-4112-b432-756c503439ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeCollateralObligationToReturnCash"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:to="loc_us-gaap_DerivativeCollateralObligationToReturnCash_97774407-a280-4112-b432-756c503439ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_cfd949b7-ebc1-4513-a2f7-a355f0077f7d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeAssetsAbstract_a79b721b-aa8b-482a-b3b2-91f3895be79d" xlink:to="loc_us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_cfd949b7-ebc1-4513-a2f7-a355f0077f7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_709e5441-e0ac-4a1a-a4d4-99a213725eca" xlink:to="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_4ff9f0b8-6f4d-4625-8922-aad07acfe69e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_4ff9f0b8-6f4d-4625-8922-aad07acfe69e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilityFairValueGrossAsset_89c7ed45-37db-47a7-b77e-45e72608ae39" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilityFairValueGrossAsset"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:to="loc_us-gaap_DerivativeLiabilityFairValueGrossAsset_89c7ed45-37db-47a7-b77e-45e72608ae39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities_219fe07c-5d1f-4e93-bf48-446df1c44117" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilities"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:to="loc_us-gaap_DerivativeLiabilities_219fe07c-5d1f-4e93-bf48-446df1c44117" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilityNotOffsetPolicyElectionDeduction_1a1b6ad0-63a9-4544-a0bf-20bf9d682f6a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilityNotOffsetPolicyElectionDeduction"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:to="loc_us-gaap_DerivativeLiabilityNotOffsetPolicyElectionDeduction_1a1b6ad0-63a9-4544-a0bf-20bf9d682f6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeCollateralRightToReclaimCash_b89e1c33-c736-45ea-bed1-beebca669922" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeCollateralRightToReclaimCash"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:to="loc_us-gaap_DerivativeCollateralRightToReclaimCash_b89e1c33-c736-45ea-bed1-beebca669922" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_8259bcbd-b606-405d-8cb1-9e3b6b455cba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLiabilitiesAbstract_4f0312ad-7a97-4e34-8f4f-3eff39bf846a" xlink:to="loc_us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_8259bcbd-b606-405d-8cb1-9e3b6b455cba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet_5aaa9898-d095-49ce-9377-883ee68a7c52" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_709e5441-e0ac-4a1a-a4d4-99a213725eca" xlink:to="loc_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet_5aaa9898-d095-49ce-9377-883ee68a7c52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementLocationandAmountofGainsLossesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#DerivativeinstrumentsandriskmanagementLocationandAmountofGainsLossesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/DerivativeinstrumentsandriskmanagementLocationandAmountofGainsLossesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_838d303c-756e-47eb-9ecb-4c0b3b665a0c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_838d303c-756e-47eb-9ecb-4c0b3b665a0c" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_aa7f5cac-4740-48f6-8afc-5565f499b16f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_aa7f5cac-4740-48f6-8afc-5565f499b16f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_ba8c425e-8566-487c-b024-4043e74e1382" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_aa7f5cac-4740-48f6-8afc-5565f499b16f" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_ba8c425e-8566-487c-b024-4043e74e1382" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SpotandForwardForeignExchangeMember_b9a83155-c2cc-4e6e-b576-c7a77386c130" xlink:href="ntb-20201231.xsd#ntb_SpotandForwardForeignExchangeMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_ba8c425e-8566-487c-b024-4043e74e1382" xlink:to="loc_ntb_SpotandForwardForeignExchangeMember_b9a83155-c2cc-4e6e-b576-c7a77386c130" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrencySwapMember_6647f016-985c-486c-859d-59707a5cdc23" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CurrencySwapMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_ba8c425e-8566-487c-b024-4043e74e1382" xlink:to="loc_us-gaap_CurrencySwapMember_6647f016-985c-486c-859d-59707a5cdc23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_6baa6243-7b88-4620-9aab-618d40d3b8f8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_6baa6243-7b88-4620-9aab-618d40d3b8f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_7cc88af4-83d0-4f91-ad60-391fba35b180" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_6baa6243-7b88-4620-9aab-618d40d3b8f8" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_7cc88af4-83d0-4f91-ad60-391fba35b180" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ForeignCurrencyTransactionGainLossbeforeTaxMember_8af0ed6a-6d29-43de-b5a9-d35c9d928d09" xlink:href="ntb-20201231.xsd#ntb_ForeignCurrencyTransactionGainLossbeforeTaxMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_7cc88af4-83d0-4f91-ad60-391fba35b180" xlink:to="loc_ntb_ForeignCurrencyTransactionGainLossbeforeTaxMember_8af0ed6a-6d29-43de-b5a9-d35c9d928d09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_a557ed03-cf33-4599-9ade-80b54f33ae4e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:to="loc_us-gaap_HedgingDesignationAxis_a557ed03-cf33-4599-9ade-80b54f33ae4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_0a5c8760-28dd-4f73-ae13-2ca1168c092b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationAxis_a557ed03-cf33-4599-9ade-80b54f33ae4e" xlink:to="loc_us-gaap_HedgingDesignationDomain_0a5c8760-28dd-4f73-ae13-2ca1168c092b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_7e375c56-3bf6-4b0a-ac5b-6ff46c8131bd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NondesignatedMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_0a5c8760-28dd-4f73-ae13-2ca1168c092b" xlink:to="loc_us-gaap_NondesignatedMember_7e375c56-3bf6-4b0a-ac5b-6ff46c8131bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_03125ab7-38d9-44a0-9ac4-cb3aeb243566" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingDesignationDomain_0a5c8760-28dd-4f73-ae13-2ca1168c092b" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_03125ab7-38d9-44a0-9ac4-cb3aeb243566" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLocationAxis_0ecf759a-017f-4cff-a2a2-d8b9626a610a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLocationAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLocationAxis_0ecf759a-017f-4cff-a2a2-d8b9626a610a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLocationDomain_93a458ce-34e9-4354-aa8f-17e4fee013c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLocationDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLocationAxis_0ecf759a-017f-4cff-a2a2-d8b9626a610a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLocationDomain_93a458ce-34e9-4354-aa8f-17e4fee013c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossForeignCurrencyTransactionandTranslationAdjustmentNetofTaxPortionAttributabletoParentMember_924ba1b6-a26a-4b0b-9ebb-ab210002612d" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossForeignCurrencyTransactionandTranslationAdjustmentNetofTaxPortionAttributabletoParentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLocationDomain_93a458ce-34e9-4354-aa8f-17e4fee013c9" xlink:to="loc_ntb_OtherComprehensiveIncomeLossForeignCurrencyTransactionandTranslationAdjustmentNetofTaxPortionAttributabletoParentMember_924ba1b6-a26a-4b0b-9ebb-ab210002612d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_8a037081-9456-44ab-9fc0-23a718d67d68" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_8a037081-9456-44ab-9fc0-23a718d67d68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_9fd18de4-8cd1-4fa6-8e53-142486b53449" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_8a037081-9456-44ab-9fc0-23a718d67d68" xlink:to="loc_us-gaap_HedgingRelationshipDomain_9fd18de4-8cd1-4fa6-8e53-142486b53449" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueHedgingMember_fafef660-e968-4cef-8cb1-6007e203ab48" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueHedgingMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingRelationshipDomain_9fd18de4-8cd1-4fa6-8e53-142486b53449" xlink:to="loc_us-gaap_FairValueHedgingMember_fafef660-e968-4cef-8cb1-6007e203ab48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetInvestmentHedgingMember_5a132c16-eab0-4a3a-a27c-938ed4dce6fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetInvestmentHedgingMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_HedgingRelationshipDomain_9fd18de4-8cd1-4fa6-8e53-142486b53449" xlink:to="loc_us-gaap_NetInvestmentHedgingMember_5a132c16-eab0-4a3a-a27c-938ed4dce6fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_b885b8f7-691c-4d28-b536-933f08bc38d8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_00c185be-9437-4cef-9582-81a08d68c279" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_b885b8f7-691c-4d28-b536-933f08bc38d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeGainLossOnDerivativeNet_045b645c-3800-4cd9-a8ad-b498333d3fec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeGainLossOnDerivativeNet"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_b885b8f7-691c-4d28-b536-933f08bc38d8" xlink:to="loc_us-gaap_DerivativeGainLossOnDerivativeNet_045b645c-3800-4cd9-a8ad-b498333d3fec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_248be739-93c3-493a-8f87-55d64ebf39f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_b885b8f7-691c-4d28-b536-933f08bc38d8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_248be739-93c3-493a-8f87-55d64ebf39f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax_397a4eb0-a890-4046-8203-098241ed5db4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_b885b8f7-691c-4d28-b536-933f08bc38d8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax_397a4eb0-a890-4046-8203-098241ed5db4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Fairvaluemeasurements" xlink:type="simple" xlink:href="ntb-20201231.xsd#Fairvaluemeasurements"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Fairvaluemeasurements" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_fc567e17-6ac8-4ab5-886e-4bbd23b84889" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_99e1cb44-aa03-44bc-be21-52eda2a67a5c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_fc567e17-6ac8-4ab5-886e-4bbd23b84889" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_99e1cb44-aa03-44bc-be21-52eda2a67a5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/FairvaluemeasurementsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#FairvaluemeasurementsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/FairvaluemeasurementsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_253394c4-d824-40fd-9cf2-3054777722cb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_4cdc5b3e-b35b-47a5-afa0-9c0a190ff415" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_253394c4-d824-40fd-9cf2-3054777722cb" xlink:to="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_4cdc5b3e-b35b-47a5-afa0-9c0a190ff415" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_4566af48-67b0-46d0-b199-232bc70ddcaa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_253394c4-d824-40fd-9cf2-3054777722cb" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_4566af48-67b0-46d0-b199-232bc70ddcaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock_399e41b1-3185-4b1f-9567-fe326e0d1caf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_253394c4-d824-40fd-9cf2-3054777722cb" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock_399e41b1-3185-4b1f-9567-fe326e0d1caf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/FairvaluemeasurementsFinancialAssetsandLiabilitiesMeasuredatFairValueDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#FairvaluemeasurementsFinancialAssetsandLiabilitiesMeasuredatFairValueDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/FairvaluemeasurementsFinancialAssetsandLiabilitiesMeasuredatFairValueDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_886d90a3-c247-486e-baf3-ce6502ad891c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_a16f0121-e117-47bc-8692-f9d4411d90eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_886d90a3-c247-486e-baf3-ce6502ad891c" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_a16f0121-e117-47bc-8692-f9d4411d90eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_8fbce8ce-3622-4b67-a4a9-7e028333ee3f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_a16f0121-e117-47bc-8692-f9d4411d90eb" xlink:to="loc_us-gaap_FinancialInstrumentAxis_8fbce8ce-3622-4b67-a4a9-7e028333ee3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_617e4e86-f5f8-4b2e-89fd-89d91e3068cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_8fbce8ce-3622-4b67-a4a9-7e028333ee3f" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_617e4e86-f5f8-4b2e-89fd-89d91e3068cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesMember_687382e0-9a41-41ea-aaac-64f8dc97ee91" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_617e4e86-f5f8-4b2e-89fd-89d91e3068cf" xlink:to="loc_us-gaap_EquitySecuritiesMember_687382e0-9a41-41ea-aaac-64f8dc97ee91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasuryAndGovernmentMember_d22697c5-0ebb-4847-90a3-1c4862b39058" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USTreasuryAndGovernmentMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_617e4e86-f5f8-4b2e-89fd-89d91e3068cf" xlink:to="loc_us-gaap_USTreasuryAndGovernmentMember_d22697c5-0ebb-4847-90a3-1c4862b39058" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_fe5cb107-658d-4def-9686-3967d4f3eec4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignGovernmentDebtSecuritiesMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_617e4e86-f5f8-4b2e-89fd-89d91e3068cf" xlink:to="loc_us-gaap_ForeignGovernmentDebtSecuritiesMember_fe5cb107-658d-4def-9686-3967d4f3eec4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_AssetbackedSecuritiesStudentLoansMember_3d85e010-017f-4382-b12e-6318ca41848b" xlink:href="ntb-20201231.xsd#ntb_AssetbackedSecuritiesStudentLoansMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_617e4e86-f5f8-4b2e-89fd-89d91e3068cf" xlink:to="loc_ntb_AssetbackedSecuritiesStudentLoansMember_3d85e010-017f-4382-b12e-6318ca41848b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_05834850-5bb7-4828-8344-b5e8a36fce2f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResidentialMortgageBackedSecuritiesMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_617e4e86-f5f8-4b2e-89fd-89d91e3068cf" xlink:to="loc_us-gaap_ResidentialMortgageBackedSecuritiesMember_05834850-5bb7-4828-8344-b5e8a36fce2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_f4c74a35-bde1-4f11-b732-e138ed6c3064" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_a16f0121-e117-47bc-8692-f9d4411d90eb" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_f4c74a35-bde1-4f11-b732-e138ed6c3064" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_7c864e48-4662-4f18-990d-dc450a41570b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_f4c74a35-bde1-4f11-b732-e138ed6c3064" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_7c864e48-4662-4f18-990d-dc450a41570b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_b4ce90e5-fbd3-40aa-9f31-6686fcdc88e7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_7c864e48-4662-4f18-990d-dc450a41570b" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_b4ce90e5-fbd3-40aa-9f31-6686fcdc88e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_cba07252-95ce-410c-9808-b45b69e99560" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_a16f0121-e117-47bc-8692-f9d4411d90eb" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_cba07252-95ce-410c-9808-b45b69e99560" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_c4ff1d7e-68a0-4402-8d56-3fa94212bab1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_cba07252-95ce-410c-9808-b45b69e99560" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_c4ff1d7e-68a0-4402-8d56-3fa94212bab1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_32dc924d-a8b9-415a-9c27-24c552281d24" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_c4ff1d7e-68a0-4402-8d56-3fa94212bab1" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_32dc924d-a8b9-415a-9c27-24c552281d24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_597074c7-dd25-4852-b845-dd5ffcd18106" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_c4ff1d7e-68a0-4402-8d56-3fa94212bab1" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_597074c7-dd25-4852-b845-dd5ffcd18106" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_9f484926-b607-45e9-abdc-91ee07d3204d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_c4ff1d7e-68a0-4402-8d56-3fa94212bab1" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_9f484926-b607-45e9-abdc-91ee07d3204d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_0ef597eb-0a73-4394-bc4e-d0b6faa6135c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_a16f0121-e117-47bc-8692-f9d4411d90eb" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_0ef597eb-0a73-4394-bc4e-d0b6faa6135c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_e9a93fd7-becc-443a-9fa7-6b1427782661" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_0ef597eb-0a73-4394-bc4e-d0b6faa6135c" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_e9a93fd7-becc-443a-9fa7-6b1427782661" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_ac9e1314-d740-4c7a-a8b1-dca96433466c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_e9a93fd7-becc-443a-9fa7-6b1427782661" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_ac9e1314-d740-4c7a-a8b1-dca96433466c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_b85ccb91-f0b2-409d-b92f-dbb0eba7d82a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_e9a93fd7-becc-443a-9fa7-6b1427782661" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_b85ccb91-f0b2-409d-b92f-dbb0eba7d82a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_4889c783-d0e6-4d22-90c9-93dbc6c3beaf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssets"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_e9a93fd7-becc-443a-9fa7-6b1427782661" xlink:to="loc_us-gaap_DerivativeAssets_4889c783-d0e6-4d22-90c9-93dbc6c3beaf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b79ca0f4-c630-48e1-8d44-5bbd9dbff4a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_0ef597eb-0a73-4394-bc4e-d0b6faa6135c" xlink:to="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b79ca0f4-c630-48e1-8d44-5bbd9dbff4a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities_055a311b-cce7-4bf9-9d66-e1666c10bcdb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilities"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_b79ca0f4-c630-48e1-8d44-5bbd9dbff4a5" xlink:to="loc_us-gaap_DerivativeLiabilities_055a311b-cce7-4bf9-9d66-e1666c10bcdb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/FairvaluemeasurementsLevel3ReconciliationDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#FairvaluemeasurementsLevel3ReconciliationDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/FairvaluemeasurementsLevel3ReconciliationDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_84a65e59-f18f-4bb7-a632-7549df7ffc2f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_b4aea1c5-33c3-4e6e-9fa3-70a016894a31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_84a65e59-f18f-4bb7-a632-7549df7ffc2f" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_b4aea1c5-33c3-4e6e-9fa3-70a016894a31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByAssetClassAxis_759a7856-21f3-4928-93f9-ca1dc534ce5a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByAssetClassAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_b4aea1c5-33c3-4e6e-9fa3-70a016894a31" xlink:to="loc_us-gaap_FairValueByAssetClassAxis_759a7856-21f3-4928-93f9-ca1dc534ce5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_1db3f3ca-b283-4bb9-b1f5-f2abb1eb30e5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByAssetClassAxis_759a7856-21f3-4928-93f9-ca1dc534ce5a" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_1db3f3ca-b283-4bb9-b1f5-f2abb1eb30e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableforsaleSecuritiesMember_ef720a56-9a41-46eb-9791-6f9682d7faa8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableforsaleSecuritiesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_1db3f3ca-b283-4bb9-b1f5-f2abb1eb30e5" xlink:to="loc_us-gaap_AvailableforsaleSecuritiesMember_ef720a56-9a41-46eb-9791-6f9682d7faa8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_fb9192dd-403c-4702-8444-1bbfb876b2ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_b4aea1c5-33c3-4e6e-9fa3-70a016894a31" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_fb9192dd-403c-4702-8444-1bbfb876b2ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_ba0a323a-7bec-4ba1-961e-8a08fb4f55f3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_fb9192dd-403c-4702-8444-1bbfb876b2ce" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_ba0a323a-7bec-4ba1-961e-8a08fb4f55f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_62d62128-b524-41ac-b2c6-5b3bf154844f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_ba0a323a-7bec-4ba1-961e-8a08fb4f55f3" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_62d62128-b524-41ac-b2c6-5b3bf154844f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInOtherComprehensiveIncomeLoss_bfc57cf3-39b8-4c14-91a1-e78e3b9f8279" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInOtherComprehensiveIncomeLoss"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_ba0a323a-7bec-4ba1-961e-8a08fb4f55f3" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInOtherComprehensiveIncomeLoss_bfc57cf3-39b8-4c14-91a1-e78e3b9f8279" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_acd93664-8fe3-49e4-9ecb-32a3169eae01" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_ba0a323a-7bec-4ba1-961e-8a08fb4f55f3" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_acd93664-8fe3-49e4-9ecb-32a3169eae01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisChangeInUnrealizedGainLoss_0b4deeed-3d4c-4bc1-94b1-cede0b8fc462" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisChangeInUnrealizedGainLoss"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_ba0a323a-7bec-4ba1-961e-8a08fb4f55f3" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisChangeInUnrealizedGainLoss_0b4deeed-3d4c-4bc1-94b1-cede0b8fc462" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/FairvaluemeasurementsItemsOtherThanThoseRecognizedatFairValueonaRecurringBasisDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#FairvaluemeasurementsItemsOtherThanThoseRecognizedatFairValueonaRecurringBasisDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/FairvaluemeasurementsItemsOtherThanThoseRecognizedatFairValueonaRecurringBasisDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_b9e5888f-02c5-498e-99e3-853050c3b6cb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_76bad157-11fe-4767-8687-cc861e6e42fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_b9e5888f-02c5-498e-99e3-853050c3b6cb" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_76bad157-11fe-4767-8687-cc861e6e42fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementBasisAxis_16f901e3-b702-4d11-ad28-447d2be6803d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementBasisAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_76bad157-11fe-4767-8687-cc861e6e42fe" xlink:to="loc_us-gaap_FairValueByMeasurementBasisAxis_16f901e3-b702-4d11-ad28-447d2be6803d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosureItemAmountsDomain_ece4b487-3994-44b3-9721-eeeb8a30873b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosureItemAmountsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementBasisAxis_16f901e3-b702-4d11-ad28-447d2be6803d" xlink:to="loc_us-gaap_FairValueDisclosureItemAmountsDomain_ece4b487-3994-44b3-9721-eeeb8a30873b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_f95ead7f-c6de-40ed-9dbb-b9819f34ba97" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PortionAtFairValueFairValueDisclosureMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosureItemAmountsDomain_ece4b487-3994-44b3-9721-eeeb8a30873b" xlink:to="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_f95ead7f-c6de-40ed-9dbb-b9819f34ba97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CarryingReportedAmountFairValueDisclosureMember_96c81599-81fa-4974-aa23-1c512656f8ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CarryingReportedAmountFairValueDisclosureMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosureItemAmountsDomain_ece4b487-3994-44b3-9721-eeeb8a30873b" xlink:to="loc_us-gaap_CarryingReportedAmountFairValueDisclosureMember_96c81599-81fa-4974-aa23-1c512656f8ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EstimateOfFairValueFairValueDisclosureMember_8f6d1db6-ff17-42ec-85ff-3e4467f2496f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EstimateOfFairValueFairValueDisclosureMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosureItemAmountsDomain_ece4b487-3994-44b3-9721-eeeb8a30873b" xlink:to="loc_us-gaap_EstimateOfFairValueFairValueDisclosureMember_8f6d1db6-ff17-42ec-85ff-3e4467f2496f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChangeDuringPeriodFairValueDisclosureMember_733a9fc1-c332-4bd8-b89c-050923406014" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ChangeDuringPeriodFairValueDisclosureMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosureItemAmountsDomain_ece4b487-3994-44b3-9721-eeeb8a30873b" xlink:to="loc_us-gaap_ChangeDuringPeriodFairValueDisclosureMember_733a9fc1-c332-4bd8-b89c-050923406014" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_f3351d65-e46b-4ab3-924e-b13e3df97aea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_76bad157-11fe-4767-8687-cc861e6e42fe" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_f3351d65-e46b-4ab3-924e-b13e3df97aea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_818af034-3952-4f88-ba6a-6ede7737f85b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_f3351d65-e46b-4ab3-924e-b13e3df97aea" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_818af034-3952-4f88-ba6a-6ede7737f85b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsNonrecurringMember_e079928c-b238-4790-aed8-9ed80608cee9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsNonrecurringMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_818af034-3952-4f88-ba6a-6ede7737f85b" xlink:to="loc_us-gaap_FairValueMeasurementsNonrecurringMember_e079928c-b238-4790-aed8-9ed80608cee9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_9810e1be-eed6-4bce-885d-629f02c774c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_76bad157-11fe-4767-8687-cc861e6e42fe" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_9810e1be-eed6-4bce-885d-629f02c774c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22c02d92-e3ab-4c46-80b3-916276e77036" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_9810e1be-eed6-4bce-885d-629f02c774c5" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22c02d92-e3ab-4c46-80b3-916276e77036" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_41c790bd-9a48-481f-b075-ce39bcc95f49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22c02d92-e3ab-4c46-80b3-916276e77036" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_41c790bd-9a48-481f-b075-ce39bcc95f49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_b3739d49-5745-43b4-9ff6-c94ee7ff9d8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_22c02d92-e3ab-4c46-80b3-916276e77036" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_b3739d49-5745-43b4-9ff6-c94ee7ff9d8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAxis_a93060ed-eaad-4503-b197-a60654ff6bcb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAxis"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_76bad157-11fe-4767-8687-cc861e6e42fe" xlink:to="loc_us-gaap_CashAndCashEquivalentsAxis_a93060ed-eaad-4503-b197-a60654ff6bcb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_fadb717f-5d7a-44d2-9ff3-40590f23cf93" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAxis_a93060ed-eaad-4503-b197-a60654ff6bcb" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_fadb717f-5d7a-44d2-9ff3-40590f23cf93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TimeDepositsMember_2817fa3d-2208-4ff4-9483-b15dd6eadf0b" xlink:href="ntb-20201231.xsd#ntb_TimeDepositsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_fadb717f-5d7a-44d2-9ff3-40590f23cf93" xlink:to="loc_ntb_TimeDepositsMember_2817fa3d-2208-4ff4-9483-b15dd6eadf0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_26dff19f-55d2-4955-8e27-500de39ce634" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_76bad157-11fe-4767-8687-cc861e6e42fe" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_26dff19f-55d2-4955-8e27-500de39ce634" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_26dff19f-55d2-4955-8e27-500de39ce634" xlink:to="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_ccc86bd4-736b-408b-b216-899fd88583e3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_ccc86bd4-736b-408b-b216-899fd88583e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FederalFundsSoldAndSecuritiesBorrowedOrPurchasedUnderAgreementsToResellFairValueDisclosure_998cfd56-2396-4e76-95bd-8be1c2d0cd01" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FederalFundsSoldAndSecuritiesBorrowedOrPurchasedUnderAgreementsToResellFairValueDisclosure"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:to="loc_us-gaap_FederalFundsSoldAndSecuritiesBorrowedOrPurchasedUnderAgreementsToResellFairValueDisclosure_998cfd56-2396-4e76-95bd-8be1c2d0cd01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherShortTermInvestments_9977cb0a-eb74-48ab-8e1d-29616c392d8c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherShortTermInvestments"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:to="loc_us-gaap_OtherShortTermInvestments_9977cb0a-eb74-48ab-8e1d-29616c392d8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_a409be29-a1d7-4db6-a261-293af747068e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesFairValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesFairValue_a409be29-a1d7-4db6-a261-293af747068e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansReceivableFairValueDisclosure_638ffeb2-d9d7-4374-ac40-5588331cbe16" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoansReceivableFairValueDisclosure"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:to="loc_us-gaap_LoansReceivableFairValueDisclosure_638ffeb2-d9d7-4374-ac40-5588331cbe16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherRealEstate_873e0095-bac3-4fb3-98fe-22c68a107352" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherRealEstate"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract_b281af21-2a63-4319-805e-84c1c5761db7" xlink:to="loc_us-gaap_OtherRealEstate_873e0095-bac3-4fb3-98fe-22c68a107352" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_ebf7ea86-4ab2-4c79-bd0f-338eeb1a7c79" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_26dff19f-55d2-4955-8e27-500de39ce634" xlink:to="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_ebf7ea86-4ab2-4c79-bd0f-338eeb1a7c79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsFairValueDisclosure_42a0d9bd-1f8f-45e7-996b-b057068ebb34" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsFairValueDisclosure"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_ebf7ea86-4ab2-4c79-bd0f-338eeb1a7c79" xlink:to="loc_us-gaap_DepositsFairValueDisclosure_42a0d9bd-1f8f-45e7-996b-b057068ebb34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFairValue_2369d96d-3926-4e68-a102-36888b558c56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentFairValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_ebf7ea86-4ab2-4c79-bd0f-338eeb1a7c79" xlink:to="loc_us-gaap_DebtInstrumentFairValue_2369d96d-3926-4e68-a102-36888b558c56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Interestraterisk" xlink:type="simple" xlink:href="ntb-20201231.xsd#Interestraterisk"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Interestraterisk" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_22ee5bb1-a9bc-46a4-a9ff-8c0b9c028ba2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_e42de9a9-adea-4ed5-b3cd-07468b82cd60" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_22ee5bb1-a9bc-46a4-a9ff-8c0b9c028ba2" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_e42de9a9-adea-4ed5-b3cd-07468b82cd60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InterestrateriskTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#InterestrateriskTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InterestrateriskTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_b7c28b16-6dac-4260-853f-02c4542f5d87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskTextBlock_e6debe58-ffd6-4af8-a94d-ed9e532b73c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_b7c28b16-6dac-4260-853f-02c4542f5d87" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskTextBlock_e6debe58-ffd6-4af8-a94d-ed9e532b73c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/InterestrateriskDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#InterestrateriskDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/InterestrateriskDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_4177f295-f546-46d1-81d8-54d901d2dae1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskTable_a3c6e027-ef40-4a86-a423-ddb56eede70d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_4177f295-f546-46d1-81d8-54d901d2dae1" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskTable_a3c6e027-ef40-4a86-a423-ddb56eede70d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskDisclosureItemsAxis_ec8f0d7d-6662-4adf-8474-a16a6af20b25" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskDisclosureItemsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskTable_a3c6e027-ef40-4a86-a423-ddb56eede70d" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskDisclosureItemsAxis_ec8f0d7d-6662-4adf-8474-a16a6af20b25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskDisclosureItemsDomain_354f3a41-bf7c-49b5-8985-3127bc5cd0fa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskDisclosureItemsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskDisclosureItemsAxis_ec8f0d7d-6662-4adf-8474-a16a6af20b25" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskDisclosureItemsDomain_354f3a41-bf7c-49b5-8985-3127bc5cd0fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskMarketRiskManagementGapAnalysisMember_dcc2d489-b3d7-421e-a3ee-a555481b0347" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskMarketRiskManagementGapAnalysisMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskDisclosureItemsDomain_354f3a41-bf7c-49b5-8985-3127bc5cd0fa" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskMarketRiskManagementGapAnalysisMember_dcc2d489-b3d7-421e-a3ee-a555481b0347" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FundTypeAxis_f31ea6d6-3e5f-4dcf-ac45-85083c104dae" xlink:href="ntb-20201231.xsd#ntb_FundTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskTable_a3c6e027-ef40-4a86-a423-ddb56eede70d" xlink:to="loc_ntb_FundTypeAxis_f31ea6d6-3e5f-4dcf-ac45-85083c104dae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FundTypeDomain_ce95c296-b302-49e1-8389-8a66d10da050" xlink:href="ntb-20201231.xsd#ntb_FundTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FundTypeAxis_f31ea6d6-3e5f-4dcf-ac45-85083c104dae" xlink:to="loc_ntb_FundTypeDomain_ce95c296-b302-49e1-8389-8a66d10da050" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InterestBearingFundsMember_7b2945e9-44c5-4012-a491-fec9e8ffd543" xlink:href="ntb-20201231.xsd#ntb_InterestBearingFundsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FundTypeDomain_ce95c296-b302-49e1-8389-8a66d10da050" xlink:to="loc_ntb_InterestBearingFundsMember_7b2945e9-44c5-4012-a491-fec9e8ffd543" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NonInterestBearingFundsMember_ca386491-8246-4c9b-87b0-50158fc80754" xlink:href="ntb-20201231.xsd#ntb_NonInterestBearingFundsMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FundTypeDomain_ce95c296-b302-49e1-8389-8a66d10da050" xlink:to="loc_ntb_NonInterestBearingFundsMember_ca386491-8246-4c9b-87b0-50158fc80754" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationAxis_57c66391-7e26-41ef-b094-ea8a12d7c044" xlink:href="ntb-20201231.xsd#ntb_EarlierofContractualMaturityorRepricingDateDurationAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskTable_a3c6e027-ef40-4a86-a423-ddb56eede70d" xlink:to="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationAxis_57c66391-7e26-41ef-b094-ea8a12d7c044" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationDomain_46a7d281-5770-4404-8f4b-d27dfea2fc2b" xlink:href="ntb-20201231.xsd#ntb_EarlierofContractualMaturityorRepricingDateDurationDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationAxis_57c66391-7e26-41ef-b094-ea8a12d7c044" xlink:to="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationDomain_46a7d281-5770-4404-8f4b-d27dfea2fc2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_Within3MonthsMember_c2a3c730-bed7-40a8-8320-9255e6f78326" xlink:href="ntb-20201231.xsd#ntb_Within3MonthsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationDomain_46a7d281-5770-4404-8f4b-d27dfea2fc2b" xlink:to="loc_ntb_Within3MonthsMember_c2a3c730-bed7-40a8-8320-9255e6f78326" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_Threeto6monthsMember_9c1b0d7e-a4e6-4baf-b8f5-23eb436cfaf1" xlink:href="ntb-20201231.xsd#ntb_Threeto6monthsMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationDomain_46a7d281-5770-4404-8f4b-d27dfea2fc2b" xlink:to="loc_ntb_Threeto6monthsMember_9c1b0d7e-a4e6-4baf-b8f5-23eb436cfaf1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_Sixto12MonthsMember_678f5bbf-2ecd-4290-8359-f4db2102b87c" xlink:href="ntb-20201231.xsd#ntb_Sixto12MonthsMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationDomain_46a7d281-5770-4404-8f4b-d27dfea2fc2b" xlink:to="loc_ntb_Sixto12MonthsMember_678f5bbf-2ecd-4290-8359-f4db2102b87c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_Oneto5yearsMember_9b208d96-d0ae-48bc-9d98-4f55ce3f17de" xlink:href="ntb-20201231.xsd#ntb_Oneto5yearsMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationDomain_46a7d281-5770-4404-8f4b-d27dfea2fc2b" xlink:to="loc_ntb_Oneto5yearsMember_9b208d96-d0ae-48bc-9d98-4f55ce3f17de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_After5YearsMember_b4edabe0-7381-49de-9d57-c4b769947bf1" xlink:href="ntb-20201231.xsd#ntb_After5YearsMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_EarlierofContractualMaturityorRepricingDateDurationDomain_46a7d281-5770-4404-8f4b-d27dfea2fc2b" xlink:to="loc_ntb_After5YearsMember_b4edabe0-7381-49de-9d57-c4b769947bf1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskFinancialStatementCaptionsLineItems_7321ccff-1de9-4057-957b-0bbd69f739a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskFinancialStatementCaptionsLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskTable_a3c6e027-ef40-4a86-a423-ddb56eede70d" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskFinancialStatementCaptionsLineItems_7321ccff-1de9-4057-957b-0bbd69f739a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialStatementCaptionsLineItems_7321ccff-1de9-4057-957b-0bbd69f739a1" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskCashAndCashEquivalents_a91d6e78-48f4-43fc-9834-507b56481c89" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskCashAndCashEquivalents"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskCashAndCashEquivalents_a91d6e78-48f4-43fc-9834-507b56481c89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskSecuritiesPurchasedunderAgreementstoResell_5991150d-fb37-4abd-b377-c680ee002dd0" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskSecuritiesPurchasedunderAgreementstoResell"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:to="loc_ntb_FairValueConcentrationofRiskSecuritiesPurchasedunderAgreementstoResell_5991150d-fb37-4abd-b377-c680ee002dd0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskShortTermInvestments_4b35866f-d9a4-4007-b576-27030cb0ff1e" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskShortTermInvestments"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:to="loc_ntb_FairValueConcentrationofRiskShortTermInvestments_4b35866f-d9a4-4007-b576-27030cb0ff1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskInvestments_b42f1942-12fd-4044-833e-174484236f86" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskInvestments"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskInvestments_b42f1942-12fd-4044-833e-174484236f86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueConcentrationOfRiskLoansReceivable_699457fa-d340-4556-9891-72327234b686" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueConcentrationOfRiskLoansReceivable"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:to="loc_us-gaap_FairValueConcentrationOfRiskLoansReceivable_699457fa-d340-4556-9891-72327234b686" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskOtherAssets_50a24ee9-3095-43ce-ac94-ab41e3764ff6" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskOtherAssets"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:to="loc_ntb_FairValueConcentrationofRiskOtherAssets_50a24ee9-3095-43ce-ac94-ab41e3764ff6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskAssets_0a3d8af7-e98d-4d11-b5eb-040d9dab5ab9" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskAssets"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialAssetsBalanceSheetGroupingsAbstract_f644575f-eb8c-4ffb-a3b4-424aa4f54d3e" xlink:to="loc_ntb_FairValueConcentrationofRiskAssets_0a3d8af7-e98d-4d11-b5eb-040d9dab5ab9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialStatementCaptionsLineItems_7321ccff-1de9-4057-957b-0bbd69f739a1" xlink:to="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskShareholdersEquity_b7bfb2ed-daad-439c-ad80-dffef2bcb5b0" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskShareholdersEquity"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:to="loc_ntb_FairValueConcentrationofRiskShareholdersEquity_b7bfb2ed-daad-439c-ad80-dffef2bcb5b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskDemandDepositAccounts_6dad5257-94c0-4cd5-b0e9-007719ead558" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskDemandDepositAccounts"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:to="loc_ntb_FairValueConcentrationofRiskDemandDepositAccounts_6dad5257-94c0-4cd5-b0e9-007719ead558" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskTimeDeposits_5ce78464-a1fa-4a2a-b3ed-0e25a24719b1" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskTimeDeposits"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:to="loc_ntb_FairValueConcentrationofRiskTimeDeposits_5ce78464-a1fa-4a2a-b3ed-0e25a24719b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskOtherLiabilities_85d58f1a-4cd6-4a8f-b095-59a29b55b6e2" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskOtherLiabilities"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:to="loc_ntb_FairValueConcentrationofRiskOtherLiabilities_85d58f1a-4cd6-4a8f-b095-59a29b55b6e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskLongTermDebt_c83ae736-7258-447d-a649-de2df8c3f0ae" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskLongTermDebt"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:to="loc_ntb_FairValueConcentrationofRiskLongTermDebt_c83ae736-7258-447d-a649-de2df8c3f0ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskLiabilitiesandShareholdersEquity_2a0e7b93-fd95-4519-be9a-e5af5f41c891" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskLiabilitiesandShareholdersEquity"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_FairValueConcentrationofRiskFinancialLiabilitiesandShareholdersEquityBalanceSheetGroupingsAbstract_fc618d37-ea50-473e-babc-9d16299f86a6" xlink:to="loc_ntb_FairValueConcentrationofRiskLiabilitiesandShareholdersEquity_2a0e7b93-fd95-4519-be9a-e5af5f41c891" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskInterestRateSensitivityGap_d7eae4ee-c01a-497b-9eb9-026213c8532d" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskInterestRateSensitivityGap"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialStatementCaptionsLineItems_7321ccff-1de9-4057-957b-0bbd69f739a1" xlink:to="loc_ntb_FairValueConcentrationofRiskInterestRateSensitivityGap_d7eae4ee-c01a-497b-9eb9-026213c8532d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_FairValueConcentrationofRiskCumulativeInterestRateSensitivityGap_6f221aa7-0226-48c4-86a9-31c9c4124e13" xlink:href="ntb-20201231.xsd#ntb_FairValueConcentrationofRiskCumulativeInterestRateSensitivityGap"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueConcentrationOfRiskFinancialStatementCaptionsLineItems_7321ccff-1de9-4057-957b-0bbd69f739a1" xlink:to="loc_ntb_FairValueConcentrationofRiskCumulativeInterestRateSensitivityGap_6f221aa7-0226-48c4-86a9-31c9c4124e13" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Longtermdebt" xlink:type="simple" xlink:href="ntb-20201231.xsd#Longtermdebt"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Longtermdebt" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_e29441ee-9d92-458b-95ff-532a854f8c27" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_61dba453-32b7-406c-ba3f-2bfe78457543" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_e29441ee-9d92-458b-95ff-532a854f8c27" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_61dba453-32b7-406c-ba3f-2bfe78457543" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LongtermdebtTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#LongtermdebtTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LongtermdebtTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_00d4f317-218b-4125-81e2-d9e9f9536620" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_a3674cd5-cbf9-487c-b765-91761a4bc5e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_00d4f317-218b-4125-81e2-d9e9f9536620" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_a3674cd5-cbf9-487c-b765-91761a4bc5e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LongtermdebtAdditionalInformationDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LongtermdebtAdditionalInformationDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LongtermdebtAdditionalInformationDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_a4864227-bbff-400d-82ee-a4c066d5b182" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_92787c83-cd2e-4924-9e50-23c67ebb2d14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_a4864227-bbff-400d-82ee-a4c066d5b182" xlink:to="loc_us-gaap_DebtInstrumentTable_92787c83-cd2e-4924-9e50-23c67ebb2d14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_c315f2ef-b40b-4d34-aa6a-6a560871294d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_92787c83-cd2e-4924-9e50-23c67ebb2d14" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_c315f2ef-b40b-4d34-aa6a-6a560871294d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_eedc8ec8-40fb-4d3f-b908-4a2db815c892" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_c315f2ef-b40b-4d34-aa6a-6a560871294d" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_eedc8ec8-40fb-4d3f-b908-4a2db815c892" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubordinatedDebtMember_6c3a10a8-091c-4942-a070-08b4ff8b406f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubordinatedDebtMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_eedc8ec8-40fb-4d3f-b908-4a2db815c892" xlink:to="loc_us-gaap_SubordinatedDebtMember_6c3a10a8-091c-4942-a070-08b4ff8b406f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_5ff887f8-b0a0-435d-b751-1d33885c82fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_92787c83-cd2e-4924-9e50-23c67ebb2d14" xlink:to="loc_us-gaap_DebtInstrumentAxis_5ff887f8-b0a0-435d-b751-1d33885c82fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_5ff887f8-b0a0-435d-b751-1d33885c82fe" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SeriesANotesDue2015Member_39a794d4-5e5b-4603-bbd9-cda52831b2c6" xlink:href="ntb-20201231.xsd#ntb_SeriesANotesDue2015Member"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_SeriesANotesDue2015Member_39a794d4-5e5b-4603-bbd9-cda52831b2c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SeriesBNotesDue2020Member_a02583ce-cc3e-4b99-b70f-58d6bb4c3d92" xlink:href="ntb-20201231.xsd#ntb_SeriesBNotesDue2020Member"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_SeriesBNotesDue2020Member_a02583ce-cc3e-4b99-b70f-58d6bb4c3d92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SeriesANotesDue2018Member_9f9573f3-2587-43bc-9c30-74b8b0e82d7d" xlink:href="ntb-20201231.xsd#ntb_SeriesANotesDue2018Member"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_SeriesANotesDue2018Member_9f9573f3-2587-43bc-9c30-74b8b0e82d7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SeriesBNotesDue2023Member_e458fd28-d402-4f21-811a-5ed091ffd056" xlink:href="ntb-20201231.xsd#ntb_SeriesBNotesDue2023Member"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_SeriesBNotesDue2023Member_e458fd28-d402-4f21-811a-5ed091ffd056" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NotesRedeemedinMay2008Member_fcc94b89-6352-4a8c-932e-f6142b11d705" xlink:href="ntb-20201231.xsd#ntb_NotesRedeemedinMay2008Member"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_NotesRedeemedinMay2008Member_fcc94b89-6352-4a8c-932e-f6142b11d705" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NotesDue2028Member_dd3756e7-991e-4479-bb90-4a0bce985afd" xlink:href="ntb-20201231.xsd#ntb_NotesDue2028Member"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_NotesDue2028Member_dd3756e7-991e-4479-bb90-4a0bce985afd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SeriesBNotesDue2018Member_1dd02edb-e8fe-42ec-9a6f-a19efc074a06" xlink:href="ntb-20201231.xsd#ntb_SeriesBNotesDue2018Member"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_SeriesBNotesDue2018Member_1dd02edb-e8fe-42ec-9a6f-a19efc074a06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NotesDue2030Member_0c56795b-260b-4a63-bf93-d15f0f1d6de3" xlink:href="ntb-20201231.xsd#ntb_NotesDue2030Member"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_e93e9d77-f5f0-4a55-a3af-8c4c85e46358" xlink:to="loc_ntb_NotesDue2030Member_0c56795b-260b-4a63-bf93-d15f0f1d6de3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis_98526ef2-af35-4408-9ffe-82a1bbf5ccaa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_92787c83-cd2e-4924-9e50-23c67ebb2d14" xlink:to="loc_us-gaap_VariableRateAxis_98526ef2-af35-4408-9ffe-82a1bbf5ccaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_c8be75a6-a6e7-44fc-b3f4-25764b1a7c11" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_98526ef2-af35-4408-9ffe-82a1bbf5ccaa" xlink:to="loc_us-gaap_VariableRateDomain_c8be75a6-a6e7-44fc-b3f4-25764b1a7c11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UsTreasuryUstInterestRateMember_a9a4b561-d481-4a62-bde4-67772838933a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UsTreasuryUstInterestRateMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_c8be75a6-a6e7-44fc-b3f4-25764b1a7c11" xlink:to="loc_us-gaap_UsTreasuryUstInterestRateMember_a9a4b561-d481-4a62-bde4-67772838933a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_92787c83-cd2e-4924-9e50-23c67ebb2d14" xlink:to="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_e5a984f7-43e1-4589-91da-2235e07acd4b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_e5a984f7-43e1-4589-91da-2235e07acd4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DebtInstrumentNumberofTranches_1d456b1b-eb43-4d30-b072-e86db7dac134" xlink:href="ntb-20201231.xsd#ntb_DebtInstrumentNumberofTranches"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_ntb_DebtInstrumentNumberofTranches_1d456b1b-eb43-4d30-b072-e86db7dac134" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_beefbae1-9df7-45fd-b0c2-a2619757886f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_beefbae1-9df7-45fd-b0c2-a2619757886f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_22684495-34cf-45ac-8fe4-b69114497c5f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_22684495-34cf-45ac-8fe4-b69114497c5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentRepurchasedFaceAmount_182e31e6-90b8-4b75-9ce1-782cc1c60709" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentRepurchasedFaceAmount"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_DebtInstrumentRepurchasedFaceAmount_182e31e6-90b8-4b75-9ce1-782cc1c60709" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_d8c70b82-46e1-4513-9135-f227d3c37feb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebt"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_LongTermDebt_d8c70b82-46e1-4513-9135-f227d3c37feb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfSubordinatedDebt_d777bd73-f449-454c-8f79-f790bfb24da8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfSubordinatedDebt"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_RepaymentsOfSubordinatedDebt_d777bd73-f449-454c-8f79-f790bfb24da8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_5ea64718-447e-4739-beca-615e85c3366b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_5ea64718-447e-4739-beca-615e85c3366b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestCostsCapitalized_491b2ace-0882-4f15-b5f4-0353506f7b8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestCostsCapitalized"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8682be2d-356d-457d-9715-e1ab8bb39d9d" xlink:to="loc_us-gaap_InterestCostsCapitalized_491b2ace-0882-4f15-b5f4-0353506f7b8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/LongtermdebtContractualMaturityDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#LongtermdebtContractualMaturityDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/LongtermdebtContractualMaturityDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_5416bf29-8a70-4900-9047-0b90504ef20d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_7f61e6cb-679d-44d6-a60f-f918cf495ed3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_5416bf29-8a70-4900-9047-0b90504ef20d" xlink:to="loc_us-gaap_DebtInstrumentTable_7f61e6cb-679d-44d6-a60f-f918cf495ed3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_7655a313-b65c-46e0-a82f-098069cd3ca5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7f61e6cb-679d-44d6-a60f-f918cf495ed3" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_7655a313-b65c-46e0-a82f-098069cd3ca5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_cbdfd928-aa5b-418f-87c5-8d1a68009e4c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_7655a313-b65c-46e0-a82f-098069cd3ca5" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_cbdfd928-aa5b-418f-87c5-8d1a68009e4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubordinatedDebtMember_0fde941d-c163-4ab2-8fd5-3d092ddf39be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubordinatedDebtMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_cbdfd928-aa5b-418f-87c5-8d1a68009e4c" xlink:to="loc_us-gaap_SubordinatedDebtMember_0fde941d-c163-4ab2-8fd5-3d092ddf39be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_fe3a1836-b273-492a-8db6-c19aaad6acc1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7f61e6cb-679d-44d6-a60f-f918cf495ed3" xlink:to="loc_us-gaap_DebtInstrumentAxis_fe3a1836-b273-492a-8db6-c19aaad6acc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_9ec8a842-bb26-44f3-9e45-9db7ae7efdaf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_fe3a1836-b273-492a-8db6-c19aaad6acc1" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_9ec8a842-bb26-44f3-9e45-9db7ae7efdaf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NotesDue2028Member_bd33db1c-8a66-431e-8a73-c6fc6b9a0935" xlink:href="ntb-20201231.xsd#ntb_NotesDue2028Member"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9ec8a842-bb26-44f3-9e45-9db7ae7efdaf" xlink:to="loc_ntb_NotesDue2028Member_bd33db1c-8a66-431e-8a73-c6fc6b9a0935" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NotesDue2030Member_3ced7de7-46cf-4bff-a441-174bc175a321" xlink:href="ntb-20201231.xsd#ntb_NotesDue2030Member"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9ec8a842-bb26-44f3-9e45-9db7ae7efdaf" xlink:to="loc_ntb_NotesDue2030Member_3ced7de7-46cf-4bff-a441-174bc175a321" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis_878f9d03-6955-465c-945a-fde239bae345" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7f61e6cb-679d-44d6-a60f-f918cf495ed3" xlink:to="loc_us-gaap_VariableRateAxis_878f9d03-6955-465c-945a-fde239bae345" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_7a69b0dd-1ac1-4212-8664-edc5ac37fac0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_878f9d03-6955-465c-945a-fde239bae345" xlink:to="loc_us-gaap_VariableRateDomain_7a69b0dd-1ac1-4212-8664-edc5ac37fac0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_bee0deec-773f-4dae-b2f3-700eb0ccc16c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_7a69b0dd-1ac1-4212-8664-edc5ac37fac0" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_bee0deec-773f-4dae-b2f3-700eb0ccc16c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7f61e6cb-679d-44d6-a60f-f918cf495ed3" xlink:to="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_4a8e27ab-262d-421e-8d9c-cba0d959688e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_4a8e27ab-262d-421e-8d9c-cba0d959688e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_7a9846fe-375a-4bad-acc4-2f0b253a626f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_7a9846fe-375a-4bad-acc4-2f0b253a626f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_ba475edc-d998-4fec-88b4-0ea46d207938" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_ba475edc-d998-4fec-88b4-0ea46d207938" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LongtermDebtMaturitiesPaymentsofInterestinNextTwelveMonths_c577fdf4-ad91-4f9b-89f5-29502b8997f0" xlink:href="ntb-20201231.xsd#ntb_LongtermDebtMaturitiesPaymentsofInterestinNextTwelveMonths"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_ntb_LongtermDebtMaturitiesPaymentsofInterestinNextTwelveMonths_c577fdf4-ad91-4f9b-89f5-29502b8997f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LongtermDebtMaturitiesPaymentsofInterestinYearsTwoThroughFive_0a1d5968-74de-4877-a78d-ec5c3c71f6a7" xlink:href="ntb-20201231.xsd#ntb_LongtermDebtMaturitiesPaymentsofInterestinYearsTwoThroughFive"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_ntb_LongtermDebtMaturitiesPaymentsofInterestinYearsTwoThroughFive_0a1d5968-74de-4877-a78d-ec5c3c71f6a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LongtermDebtMaturitiesPaymentsofInterestafterYearFive_495e101d-b99d-456d-aad3-47f5bdedb290" xlink:href="ntb-20201231.xsd#ntb_LongtermDebtMaturitiesPaymentsofInterestafterYearFive"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_ntb_LongtermDebtMaturitiesPaymentsofInterestafterYearFive_495e101d-b99d-456d-aad3-47f5bdedb290" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_ed054b7a-3b75-4421-ab14-25782f04edb1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredFinanceCostsNet"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_ed054b7a-3b75-4421-ab14-25782f04edb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_08603e72-78e0-4b98-b65a-c455a12547fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebt"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_228a1c25-93f4-4a0a-8b65-91ae8fecf8ed" xlink:to="loc_us-gaap_LongTermDebt_08603e72-78e0-4b98-b65a-c455a12547fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Earningspershare" xlink:type="simple" xlink:href="ntb-20201231.xsd#Earningspershare"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Earningspershare" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_a91da4a5-77a2-40e8-a462-130b393d17e2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_3689d6dd-d0f6-44b5-a111-f41ae6bc3a62" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_a91da4a5-77a2-40e8-a462-130b393d17e2" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_3689d6dd-d0f6-44b5-a111-f41ae6bc3a62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EarningspershareTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#EarningspershareTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EarningspershareTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_9efd6a92-2918-4020-8fac-a0e41f98eb22" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_c9ff0aaf-e3c3-4a7c-aa0e-37be88d9f4c4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_9efd6a92-2918-4020-8fac-a0e41f98eb22" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_c9ff0aaf-e3c3-4a7c-aa0e-37be88d9f4c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/EarningspershareDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#EarningspershareDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/EarningspershareDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_579aee5c-f039-4f33-a773-1dd78f4fa0a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_8b6daca4-7bab-4e19-b038-3883eaba2d10" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_579aee5c-f039-4f33-a773-1dd78f4fa0a6" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_8b6daca4-7bab-4e19-b038-3883eaba2d10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_7c1933c0-7a1d-4934-8717-fcb01feb29ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_8b6daca4-7bab-4e19-b038-3883eaba2d10" xlink:to="loc_us-gaap_StatementClassOfStockAxis_7c1933c0-7a1d-4934-8717-fcb01feb29ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_edda92cf-27fd-4a86-abb8-3c4b28063652" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_7c1933c0-7a1d-4934-8717-fcb01feb29ac" xlink:to="loc_us-gaap_ClassOfStockDomain_edda92cf-27fd-4a86-abb8-3c4b28063652" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonClassAMember_e28b8c47-b2bc-44c6-9ba6-2d1c235c7dfa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonClassAMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_edda92cf-27fd-4a86-abb8-3c4b28063652" xlink:to="loc_us-gaap_CommonClassAMember_e28b8c47-b2bc-44c6-9ba6-2d1c235c7dfa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_28e93267-e264-436d-acb5-a770f6aa4ad0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_8b6daca4-7bab-4e19-b038-3883eaba2d10" xlink:to="loc_us-gaap_ClassOfStockLineItems_28e93267-e264-436d-acb5-a770f6aa4ad0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAverageOutstandingNumber_f2085f43-56a3-4be1-89e0-05290ffe0c40" xlink:href="ntb-20201231.xsd#ntb_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAverageOutstandingNumber"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_28e93267-e264-436d-acb5-a770f6aa4ad0" xlink:to="loc_ntb_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAverageOutstandingNumber_f2085f43-56a3-4be1-89e0-05290ffe0c40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_2e4c18c2-cb3a-48c3-b203-ab9f518182e8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_28e93267-e264-436d-acb5-a770f6aa4ad0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_2e4c18c2-cb3a-48c3-b203-ab9f518182e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_d5a9c88a-736a-4fca-a527-a29d3becfad0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_28e93267-e264-436d-acb5-a770f6aa4ad0" xlink:to="loc_us-gaap_NetIncomeLoss_d5a9c88a-736a-4fca-a527-a29d3becfad0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasicAbstract_79602b33-de1f-4326-920d-0562c77bcd17" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAbstract"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_28e93267-e264-436d-acb5-a770f6aa4ad0" xlink:to="loc_us-gaap_EarningsPerShareBasicAbstract_79602b33-de1f-4326-920d-0562c77bcd17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesIssuedBasic_c1f5fbf4-f141-4ba3-b328-68a78056d768" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesIssuedBasic"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_79602b33-de1f-4326-920d-0562c77bcd17" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesIssuedBasic_c1f5fbf4-f141-4ba3-b328-68a78056d768" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesTreasuryStock_7aea0b25-b6c7-4eee-8f32-e2bd1f4a88a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesTreasuryStock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_79602b33-de1f-4326-920d-0562c77bcd17" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesTreasuryStock_7aea0b25-b6c7-4eee-8f32-e2bd1f4a88a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_23de4e8e-50dc-4103-a9bb-a44c24e37004" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_79602b33-de1f-4326-920d-0562c77bcd17" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_23de4e8e-50dc-4103-a9bb-a44c24e37004" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_06d5c753-4813-4548-a6a8-5e647c6d1a00" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasic"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_79602b33-de1f-4326-920d-0562c77bcd17" xlink:to="loc_us-gaap_EarningsPerShareBasic_06d5c753-4813-4548-a6a8-5e647c6d1a00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDilutedAbstract_40efffe9-8057-41f3-9f5f-9b933049fdfb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareDilutedAbstract"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_28e93267-e264-436d-acb5-a770f6aa4ad0" xlink:to="loc_us-gaap_EarningsPerShareDilutedAbstract_40efffe9-8057-41f3-9f5f-9b933049fdfb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_156ad26a-7ab8-4e81-a0af-673341c2c6bb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_40efffe9-8057-41f3-9f5f-9b933049fdfb" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_156ad26a-7ab8-4e81-a0af-673341c2c6bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToCallOptionsAndWarrants_7259d31f-06e7-4035-88b1-81f758144e56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToCallOptionsAndWarrants"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_40efffe9-8057-41f3-9f5f-9b933049fdfb" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToCallOptionsAndWarrants_7259d31f-06e7-4035-88b1-81f758144e56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_07b18de5-67c9-422b-9b61-927f908e6b48" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_40efffe9-8057-41f3-9f5f-9b933049fdfb" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_07b18de5-67c9-422b-9b61-927f908e6b48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_ec6be50b-b77e-4682-8916-dac8a57e9e56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_40efffe9-8057-41f3-9f5f-9b933049fdfb" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_ec6be50b-b77e-4682-8916-dac8a57e9e56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_c0d3c20f-0422-4bfa-8eb0-7f34e280851a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_40efffe9-8057-41f3-9f5f-9b933049fdfb" xlink:to="loc_us-gaap_EarningsPerShareDiluted_c0d3c20f-0422-4bfa-8eb0-7f34e280851a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Sharebasedpayments" xlink:type="simple" xlink:href="ntb-20201231.xsd#Sharebasedpayments"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Sharebasedpayments" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_84a502c7-0956-431f-bf21-9f041c743e3b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_b9208633-60df-47a9-9537-846aa08b48b5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_84a502c7-0956-431f-bf21-9f041c743e3b" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_b9208633-60df-47a9-9537-846aa08b48b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebasedpaymentsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebasedpaymentsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebasedpaymentsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_a8186787-d4da-4449-a8ea-4a098d67e17e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_bbadb7fb-0e5f-44d8-84d3-b14f006a3b8a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_a8186787-d4da-4449-a8ea-4a098d67e17e" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_bbadb7fb-0e5f-44d8-84d3-b14f006a3b8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfNonvestedShareActivityTableTextBlock_4d4770b2-3a9e-4318-a0d1-ee8e3ef2e7cc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfNonvestedShareActivityTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_a8186787-d4da-4449-a8ea-4a098d67e17e" xlink:to="loc_us-gaap_ScheduleOfNonvestedShareActivityTableTextBlock_4d4770b2-3a9e-4318-a0d1-ee8e3ef2e7cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock_c9050d9e-b3f8-4b24-bd2c-471300022f5c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_a8186787-d4da-4449-a8ea-4a098d67e17e" xlink:to="loc_us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock_c9050d9e-b3f8-4b24-bd2c-471300022f5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfUnrecognizedCompensationCostNonvestedAwardsTableTextBlock_a8349a79-a042-4d8c-bcb3-b8f4e7e7a14f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfUnrecognizedCompensationCostNonvestedAwardsTableTextBlock"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_a8186787-d4da-4449-a8ea-4a098d67e17e" xlink:to="loc_us-gaap_ScheduleOfUnrecognizedCompensationCostNonvestedAwardsTableTextBlock_a8349a79-a042-4d8c-bcb3-b8f4e7e7a14f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebasedpaymentsAdditionalInformationDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebasedpaymentsAdditionalInformationDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebasedpaymentsAdditionalInformationDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_88eabe18-0b93-4b93-b6aa-40ad4502312e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_316ad785-3f3d-4ab5-8c35-9776da816b4b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_88eabe18-0b93-4b93-b6aa-40ad4502312e" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_316ad785-3f3d-4ab5-8c35-9776da816b4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_c812f4c1-50e9-414c-b629-11133f112b12" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_316ad785-3f3d-4ab5-8c35-9776da816b4b" xlink:to="loc_us-gaap_PlanNameAxis_c812f4c1-50e9-414c-b629-11133f112b12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_c812f4c1-50e9-414c-b629-11133f112b12" xlink:to="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TwoThousandTenOmnibusPlanMember_e3c80967-b053-4825-a10a-00ba61053e04" xlink:href="ntb-20201231.xsd#ntb_TwoThousandTenOmnibusPlanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:to="loc_ntb_TwoThousandTenOmnibusPlanMember_e3c80967-b053-4825-a10a-00ba61053e04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_A2020OmnibusPlanMember_30783038-c640-4c18-8ae4-5510181962e6" xlink:href="ntb-20201231.xsd#ntb_A2020OmnibusPlanMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:to="loc_ntb_A2020OmnibusPlanMember_30783038-c640-4c18-8ae4-5510181962e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NineteenNinetySevenStockOptionPlanMember_f7fdcf2e-fa91-4ebc-b308-8b2a2b42b1ac" xlink:href="ntb-20201231.xsd#ntb_NineteenNinetySevenStockOptionPlanMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:to="loc_ntb_NineteenNinetySevenStockOptionPlanMember_f7fdcf2e-fa91-4ebc-b308-8b2a2b42b1ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_A2010And2020OmnibusPlanMember_cbc82799-326e-4256-99da-64e7669db7ca" xlink:href="ntb-20201231.xsd#ntb_A2010And2020OmnibusPlanMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:to="loc_ntb_A2010And2020OmnibusPlanMember_cbc82799-326e-4256-99da-64e7669db7ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EmployeeDeferredIncentivePlanMember_ef9cb4b9-3841-4c71-bbaa-497ba8ed76f1" xlink:href="ntb-20201231.xsd#ntb_EmployeeDeferredIncentivePlanMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:to="loc_ntb_EmployeeDeferredIncentivePlanMember_ef9cb4b9-3841-4c71-bbaa-497ba8ed76f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ExecutiveLongTermIncentiveSharePlan2016201520142013Member_09c938c0-e94f-417c-8595-66830e4d2fec" xlink:href="ntb-20201231.xsd#ntb_ExecutiveLongTermIncentiveSharePlan2016201520142013Member"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_84525976-4c5b-4844-a066-2abd581c9af8" xlink:to="loc_ntb_ExecutiveLongTermIncentiveSharePlan2016201520142013Member_09c938c0-e94f-417c-8595-66830e4d2fec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_80a4d34e-2782-4d1c-a505-e40f2d4f22c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_316ad785-3f3d-4ab5-8c35-9776da816b4b" xlink:to="loc_us-gaap_AwardTypeAxis_80a4d34e-2782-4d1c-a505-e40f2d4f22c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_80a4d34e-2782-4d1c-a505-e40f2d4f22c9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_c19ae7b4-a8f5-44e6-b649-13222b1f61a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:to="loc_us-gaap_EmployeeStockOptionMember_c19ae7b4-a8f5-44e6-b649-13222b1f61a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TimeVestingEmployeeStockOptionMember_9c315a18-1201-4372-9f72-ae15adcc35b5" xlink:href="ntb-20201231.xsd#ntb_TimeVestingEmployeeStockOptionMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:to="loc_ntb_TimeVestingEmployeeStockOptionMember_9c315a18-1201-4372-9f72-ae15adcc35b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PerformanceVestingEmployeeStockOptionMember_fc516dac-430c-4202-a6ba-2543376f8c4c" xlink:href="ntb-20201231.xsd#ntb_PerformanceVestingEmployeeStockOptionMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:to="loc_ntb_PerformanceVestingEmployeeStockOptionMember_fc516dac-430c-4202-a6ba-2543376f8c4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockCompensationPlanMember_530f2a2f-b0ea-47ab-8beb-1397fc158ebf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockCompensationPlanMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:to="loc_us-gaap_StockCompensationPlanMember_530f2a2f-b0ea-47ab-8beb-1397fc158ebf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_73e19278-25d1-4413-b679-1df58ee711c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedStockMember"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:to="loc_us-gaap_RestrictedStockMember_73e19278-25d1-4413-b679-1df58ee711c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PerformanceSharesMember_e7b7f2e7-856e-45f2-8f70-172fe033aedc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PerformanceSharesMember"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_debabdfb-9014-43c2-ba9e-d314092e8743" xlink:to="loc_us-gaap_PerformanceSharesMember_e7b7f2e7-856e-45f2-8f70-172fe033aedc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingAxis_b905dd17-537f-425a-922f-670dd32d2349" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VestingAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_316ad785-3f3d-4ab5-8c35-9776da816b4b" xlink:to="loc_us-gaap_VestingAxis_b905dd17-537f-425a-922f-670dd32d2349" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingDomain_cb4975d5-7b5e-422d-9d75-9cc073ac10a4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VestingDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingAxis_b905dd17-537f-425a-922f-670dd32d2349" xlink:to="loc_us-gaap_VestingDomain_cb4975d5-7b5e-422d-9d75-9cc073ac10a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_f1c04e34-6833-4d98-b8ff-e21ebd1d26ba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheOneMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_cb4975d5-7b5e-422d-9d75-9cc073ac10a4" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_f1c04e34-6833-4d98-b8ff-e21ebd1d26ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheTwoMember_77681083-7694-4eaa-8ee2-d4f1081fa431" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheTwoMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_cb4975d5-7b5e-422d-9d75-9cc073ac10a4" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheTwoMember_77681083-7694-4eaa-8ee2-d4f1081fa431" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheThreeMember_49acad18-941e-41c3-9545-d44bb1d71a84" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheThreeMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_cb4975d5-7b5e-422d-9d75-9cc073ac10a4" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheThreeMember_49acad18-941e-41c3-9545-d44bb1d71a84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationAwardTrancheFourMember_d3eb58e4-25d2-43d8-82db-fdbcd552205f" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationAwardTrancheFourMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_cb4975d5-7b5e-422d-9d75-9cc073ac10a4" xlink:to="loc_ntb_SharebasedCompensationAwardTrancheFourMember_d3eb58e4-25d2-43d8-82db-fdbcd552205f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_316ad785-3f3d-4ab5-8c35-9776da816b4b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense_316792c3-6845-4b7b-bb1e-9de89b41065a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense_316792c3-6845-4b7b-bb1e-9de89b41065a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EmployeeServiceSharebasedCompensationPercentofDilutedCommonSharesInitiallyAvailableforGrant_9f2192ae-0178-4ce8-85e1-d5b85c4dad01" xlink:href="ntb-20201231.xsd#ntb_EmployeeServiceSharebasedCompensationPercentofDilutedCommonSharesInitiallyAvailableforGrant"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_EmployeeServiceSharebasedCompensationPercentofDilutedCommonSharesInitiallyAvailableforGrant_9f2192ae-0178-4ce8-85e1-d5b85c4dad01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_d5eb7370-9ac4-4409-82ec-adb36671a481" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_d5eb7370-9ac4-4409-82ec-adb36671a481" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofSharesIssuedUponExerciseofEachOption_5ab5f292-9083-4a87-9f95-b335491f71a0" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofSharesIssuedUponExerciseofEachOption"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofSharesIssuedUponExerciseofEachOption_5ab5f292-9083-4a87-9f95-b335491f71a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_c56ce4d2-7038-4644-a3ad-0e87e478a319" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_c56ce4d2-7038-4644-a3ad-0e87e478a319" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_aed8251f-f69d-45e9-880a-3cc9e6009814" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_aed8251f-f69d-45e9-880a-3cc9e6009814" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_240d61eb-314c-44d1-90c9-84fd6a4d74cd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_240d61eb-314c-44d1-90c9-84fd6a4d74cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofVestingConditions_ac5936d7-49ba-40a3-9483-e8dac395e745" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofVestingConditions"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofVestingConditions_ac5936d7-49ba-40a3-9483-e8dac395e745" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPercentofOptionAwardGrantedTimeVested_00eb85e0-40d9-49a1-aba8-96c39635cb9d" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPercentofOptionAwardGrantedTimeVested"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPercentofOptionAwardGrantedTimeVested_00eb85e0-40d9-49a1-aba8-96c39635cb9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPercentofOptionAwardGrantedPerformanceVesting_2ad6460a-44c6-42d5-a6e4-a9542a51619d" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPercentofOptionAwardGrantedPerformanceVesting"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPercentofOptionAwardGrantedPerformanceVesting_2ad6460a-44c6-42d5-a6e4-a9542a51619d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardValuationEventPercentofTotalCommonSharesTransferred_39106fa7-27e5-4a08-ae40-e3ee4a2ef06d" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardValuationEventPercentofTotalCommonSharesTransferred"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardValuationEventPercentofTotalCommonSharesTransferred_39106fa7-27e5-4a08-ae40-e3ee4a2ef06d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardMultipleofInvestedCapital_c5190008-5ec3-4d59-8e28-0f22506b12a4" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardMultipleofInvestedCapital"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardMultipleofInvestedCapital_c5190008-5ec3-4d59-8e28-0f22506b12a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPerShareOriginalCapitalInvested_cfa8dd69-fc6d-4dbe-af79-1494d03d43b9" xlink:href="ntb-20201231.xsd#ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPerShareOriginalCapitalInvested"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_ntb_SharebasedCompensationArrangementbySharebasedPaymentAwardPerShareOriginalCapitalInvested_cfa8dd69-fc6d-4dbe-af79-1494d03d43b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_77ad090c-3d87-4d92-9e7b-087253a69dea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2bf94677-05b9-4181-b9fd-c6ef8531347d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_77ad090c-3d87-4d92-9e7b-087253a69dea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebasedpaymentsChangesinOutstandingStockOptionsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebasedpaymentsChangesinOutstandingStockOptionsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebasedpaymentsChangesinOutstandingStockOptionsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_4f3ea620-8f11-4be8-abd9-ef86cc924f0f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4671654-e8f4-4ad5-bf5c-61c3eaedb536" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_4f3ea620-8f11-4be8-abd9-ef86cc924f0f" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4671654-e8f4-4ad5-bf5c-61c3eaedb536" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_4cd6fd73-be3a-47e3-b3f2-6881701039da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4671654-e8f4-4ad5-bf5c-61c3eaedb536" xlink:to="loc_us-gaap_PlanNameAxis_4cd6fd73-be3a-47e3-b3f2-6881701039da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_763c59e0-5e04-471f-90bd-b99398855a27" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_4cd6fd73-be3a-47e3-b3f2-6881701039da" xlink:to="loc_us-gaap_PlanNameDomain_763c59e0-5e04-471f-90bd-b99398855a27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NineteenNinetySevenStockOptionPlanMember_4ad266ee-6add-4cdd-80f1-5a751a73f808" xlink:href="ntb-20201231.xsd#ntb_NineteenNinetySevenStockOptionPlanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_763c59e0-5e04-471f-90bd-b99398855a27" xlink:to="loc_ntb_NineteenNinetySevenStockOptionPlanMember_4ad266ee-6add-4cdd-80f1-5a751a73f808" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TwoThousandTenOmnibusPlanMember_ef514904-cc55-4ca1-85da-9ba4c366009e" xlink:href="ntb-20201231.xsd#ntb_TwoThousandTenOmnibusPlanMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_763c59e0-5e04-471f-90bd-b99398855a27" xlink:to="loc_ntb_TwoThousandTenOmnibusPlanMember_ef514904-cc55-4ca1-85da-9ba4c366009e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f3cd10fb-57ac-4c6c-b3cf-18c745d398a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4671654-e8f4-4ad5-bf5c-61c3eaedb536" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f3cd10fb-57ac-4c6c-b3cf-18c745d398a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0969442e-7ffa-4481-81fc-5136cb7fc005" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f3cd10fb-57ac-4c6c-b3cf-18c745d398a1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0969442e-7ffa-4481-81fc-5136cb7fc005" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_021bfb32-d6b5-4c41-a7a1-e86a8fb344b9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0969442e-7ffa-4481-81fc-5136cb7fc005" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_021bfb32-d6b5-4c41-a7a1-e86a8fb344b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_653742f5-c9a4-40bb-9ab8-e01e0d237bc3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0969442e-7ffa-4481-81fc-5136cb7fc005" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_653742f5-c9a4-40bb-9ab8-e01e0d237bc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_3e4f549c-f3a2-483a-92e4-cd5bbcfcf1ba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0969442e-7ffa-4481-81fc-5136cb7fc005" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_3e4f549c-f3a2-483a-92e4-cd5bbcfcf1ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_aafed03a-97df-4210-8985-5d366beea4a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0969442e-7ffa-4481-81fc-5136cb7fc005" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_aafed03a-97df-4210-8985-5d366beea4a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableNumber_a8624a80-6c8b-43c9-9c2a-15cea0f3e5c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableNumber"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f3cd10fb-57ac-4c6c-b3cf-18c745d398a1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableNumber_a8624a80-6c8b-43c9-9c2a-15cea0f3e5c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_7dc39fa0-fe75-4367-9d91-d7ab4ad6cca6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f3cd10fb-57ac-4c6c-b3cf-18c745d398a1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_7dc39fa0-fe75-4367-9d91-d7ab4ad6cca6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_56d900a7-e25d-482f-9b3e-0592f6df174a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_7dc39fa0-fe75-4367-9d91-d7ab4ad6cca6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_56d900a7-e25d-482f-9b3e-0592f6df174a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_1b0cd649-93b8-41ae-ba2d-d08183adce37" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_7dc39fa0-fe75-4367-9d91-d7ab4ad6cca6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_1b0cd649-93b8-41ae-ba2d-d08183adce37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_4f9e426a-fa45-45c3-a914-330e3ca3bddf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_7dc39fa0-fe75-4367-9d91-d7ab4ad6cca6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_4f9e426a-fa45-45c3-a914-330e3ca3bddf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_41eb56b6-7a5a-4cb3-bdc3-6041e55cf439" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_7dc39fa0-fe75-4367-9d91-d7ab4ad6cca6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_41eb56b6-7a5a-4cb3-bdc3-6041e55cf439" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_8510a8f9-8af9-466c-bbea-72c68a63db6a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f3cd10fb-57ac-4c6c-b3cf-18c745d398a1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_8510a8f9-8af9-466c-bbea-72c68a63db6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_c08434c5-0a27-4b02-9e4e-b09d482a18e5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f3cd10fb-57ac-4c6c-b3cf-18c745d398a1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_c08434c5-0a27-4b02-9e4e-b09d482a18e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_2eeaebac-27e9-49a5-8aa2-20783d1235ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_c08434c5-0a27-4b02-9e4e-b09d482a18e5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_2eeaebac-27e9-49a5-8aa2-20783d1235ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1_138cbc1f-593e-4b0d-a98a-6f3991c7b02d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_c08434c5-0a27-4b02-9e4e-b09d482a18e5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1_138cbc1f-593e-4b0d-a98a-6f3991c7b02d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_23be90a6-05dc-4bbd-8512-ffa23516b67d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_c08434c5-0a27-4b02-9e4e-b09d482a18e5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_23be90a6-05dc-4bbd-8512-ffa23516b67d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_1af0af66-5457-43c6-b85b-65f24cfea17b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_c08434c5-0a27-4b02-9e4e-b09d482a18e5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_1af0af66-5457-43c6-b85b-65f24cfea17b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebasedpaymentsChangesinOutstandingELTIPandEDIPAwardsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebasedpaymentsChangesinOutstandingELTIPandEDIPAwardsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebasedpaymentsChangesinOutstandingELTIPandEDIPAwardsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_0496beaa-afea-426b-a5e3-d45be17ef8f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f4f8320c-1a15-4f82-86af-1334185f973f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_0496beaa-afea-426b-a5e3-d45be17ef8f0" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f4f8320c-1a15-4f82-86af-1334185f973f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_8ee5c134-652c-448e-9863-2f45a444d9ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f4f8320c-1a15-4f82-86af-1334185f973f" xlink:to="loc_us-gaap_PlanNameAxis_8ee5c134-652c-448e-9863-2f45a444d9ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_15da880d-493b-4850-abd3-6db93d113e79" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_8ee5c134-652c-448e-9863-2f45a444d9ce" xlink:to="loc_us-gaap_PlanNameDomain_15da880d-493b-4850-abd3-6db93d113e79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EmployeeDeferredIncentivePlanMember_3e6cd7b2-d121-48b3-9add-97118171fa2b" xlink:href="ntb-20201231.xsd#ntb_EmployeeDeferredIncentivePlanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_15da880d-493b-4850-abd3-6db93d113e79" xlink:to="loc_ntb_EmployeeDeferredIncentivePlanMember_3e6cd7b2-d121-48b3-9add-97118171fa2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ExecutiveLongTermIncentiveSharePlanMember_5a3cfa2c-95a3-41b2-a807-9a7b61dc707d" xlink:href="ntb-20201231.xsd#ntb_ExecutiveLongTermIncentiveSharePlanMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_15da880d-493b-4850-abd3-6db93d113e79" xlink:to="loc_ntb_ExecutiveLongTermIncentiveSharePlanMember_5a3cfa2c-95a3-41b2-a807-9a7b61dc707d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EmployeeDeferredIncentivePlanandExecutiveLongTermIncentiveSharePlanMember_1cf7e44d-fd7e-444d-ad3d-a423a6f41651" xlink:href="ntb-20201231.xsd#ntb_EmployeeDeferredIncentivePlanandExecutiveLongTermIncentiveSharePlanMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_15da880d-493b-4850-abd3-6db93d113e79" xlink:to="loc_ntb_EmployeeDeferredIncentivePlanandExecutiveLongTermIncentiveSharePlanMember_1cf7e44d-fd7e-444d-ad3d-a423a6f41651" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_ffb628b7-e938-444e-8c60-b44ccd63fed7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f4f8320c-1a15-4f82-86af-1334185f973f" xlink:to="loc_us-gaap_AwardTypeAxis_ffb628b7-e938-444e-8c60-b44ccd63fed7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_cbf312ef-24ef-4486-a1d9-894d7ba1f3f6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_ffb628b7-e938-444e-8c60-b44ccd63fed7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_cbf312ef-24ef-4486-a1d9-894d7ba1f3f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TimeVestingSharesandPerformanceSharesMember_ec1ee4bb-eceb-42e9-a447-224d0f3c384d" xlink:href="ntb-20201231.xsd#ntb_TimeVestingSharesandPerformanceSharesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_cbf312ef-24ef-4486-a1d9-894d7ba1f3f6" xlink:to="loc_ntb_TimeVestingSharesandPerformanceSharesMember_ec1ee4bb-eceb-42e9-a447-224d0f3c384d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_b5f8ee0f-af5e-42e0-a8bd-a86e4b747fda" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedStockMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TimeVestingSharesandPerformanceSharesMember_ec1ee4bb-eceb-42e9-a447-224d0f3c384d" xlink:to="loc_us-gaap_RestrictedStockMember_b5f8ee0f-af5e-42e0-a8bd-a86e4b747fda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PerformanceSharesMember_f3cde176-2fe5-4889-aa3e-54160e0b0c06" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PerformanceSharesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TimeVestingSharesandPerformanceSharesMember_ec1ee4bb-eceb-42e9-a447-224d0f3c384d" xlink:to="loc_us-gaap_PerformanceSharesMember_f3cde176-2fe5-4889-aa3e-54160e0b0c06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_edc0b909-b8d1-4ee5-be35-817d14f9543e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f4f8320c-1a15-4f82-86af-1334185f973f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_edc0b909-b8d1-4ee5-be35-817d14f9543e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_13386085-0ee1-4d55-8c94-409966214192" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_edc0b909-b8d1-4ee5-be35-817d14f9543e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_13386085-0ee1-4d55-8c94-409966214192" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_1d200899-4e1e-49b4-89b5-cf4f9841d6f3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_13386085-0ee1-4d55-8c94-409966214192" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_1d200899-4e1e-49b4-89b5-cf4f9841d6f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_bc50a20f-7d07-4538-b9cf-3e9f42de8ab9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_13386085-0ee1-4d55-8c94-409966214192" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_bc50a20f-7d07-4538-b9cf-3e9f42de8ab9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_628f33e0-d6e4-4fdc-be0b-41a3daf6d559" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_13386085-0ee1-4d55-8c94-409966214192" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_628f33e0-d6e4-4fdc-be0b-41a3daf6d559" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_9bec9b66-f06d-4687-a7d5-7eeeeccdb1e5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_13386085-0ee1-4d55-8c94-409966214192" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_9bec9b66-f06d-4687-a7d5-7eeeeccdb1e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_da9fa13b-5fcc-4a9c-a495-995eb0ec4d5b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_13386085-0ee1-4d55-8c94-409966214192" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_da9fa13b-5fcc-4a9c-a495-995eb0ec4d5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested_d37374e4-d79e-4ae6-99da-1e538051198e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_edc0b909-b8d1-4ee5-be35-817d14f9543e" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested_d37374e4-d79e-4ae6-99da-1e538051198e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_7b3aba65-2a09-47a9-972f-b13fd5f1369c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_edc0b909-b8d1-4ee5-be35-817d14f9543e" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_7b3aba65-2a09-47a9-972f-b13fd5f1369c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebasedpaymentsSharebasedCompensationCostRecognizedinNetIncomeDetailsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebasedpaymentsSharebasedCompensationCostRecognizedinNetIncomeDetailsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebasedpaymentsSharebasedCompensationCostRecognizedinNetIncomeDetailsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2681a587-40a2-494b-8b60-4afac0a3834d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_ed7e54b1-92a2-4a0c-8010-5052aeefbdba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2681a587-40a2-494b-8b60-4afac0a3834d" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_ed7e54b1-92a2-4a0c-8010-5052aeefbdba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_acde2ed7-b3dd-48aa-88dd-67e917ab72c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_ed7e54b1-92a2-4a0c-8010-5052aeefbdba" xlink:to="loc_us-gaap_PlanNameAxis_acde2ed7-b3dd-48aa-88dd-67e917ab72c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_1015320b-3433-4be2-9c8a-9f370d61b310" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_acde2ed7-b3dd-48aa-88dd-67e917ab72c0" xlink:to="loc_us-gaap_PlanNameDomain_1015320b-3433-4be2-9c8a-9f370d61b310" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EmployeeDeferredIncentivePlanandExecutiveLongTermIncentiveSharePlanMember_293961f3-e96c-4f59-b629-d56fa9c0a279" xlink:href="ntb-20201231.xsd#ntb_EmployeeDeferredIncentivePlanandExecutiveLongTermIncentiveSharePlanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_1015320b-3433-4be2-9c8a-9f370d61b310" xlink:to="loc_ntb_EmployeeDeferredIncentivePlanandExecutiveLongTermIncentiveSharePlanMember_293961f3-e96c-4f59-b629-d56fa9c0a279" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_363c1288-7e46-4c20-8c8b-18c1304318e2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_ed7e54b1-92a2-4a0c-8010-5052aeefbdba" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_363c1288-7e46-4c20-8c8b-18c1304318e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_2cd37a05-2970-4e4b-bd10-c0397322458c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_363c1288-7e46-4c20-8c8b-18c1304318e2" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_2cd37a05-2970-4e4b-bd10-c0397322458c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebasedpaymentsUnrecognizedSharebasedCompensationCostDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebasedpaymentsUnrecognizedSharebasedCompensationCostDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebasedpaymentsUnrecognizedSharebasedCompensationCostDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_4ee13e6c-1715-4b37-8a7f-55f0b45f4ac8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_86122dbf-66b8-4f47-b00b-1f23d41634ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_4ee13e6c-1715-4b37-8a7f-55f0b45f4ac8" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_86122dbf-66b8-4f47-b00b-1f23d41634ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_5251c380-8948-4752-a4b3-a6114f411b46" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_86122dbf-66b8-4f47-b00b-1f23d41634ec" xlink:to="loc_us-gaap_PlanNameAxis_5251c380-8948-4752-a4b3-a6114f411b46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_b1207f34-7e73-4118-878c-fe56d215820f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_5251c380-8948-4752-a4b3-a6114f411b46" xlink:to="loc_us-gaap_PlanNameDomain_b1207f34-7e73-4118-878c-fe56d215820f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_EmployeeDeferredIncentivePlanMember_039fa046-4dc5-4e5e-947b-2abb2881abd7" xlink:href="ntb-20201231.xsd#ntb_EmployeeDeferredIncentivePlanMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_b1207f34-7e73-4118-878c-fe56d215820f" xlink:to="loc_ntb_EmployeeDeferredIncentivePlanMember_039fa046-4dc5-4e5e-947b-2abb2881abd7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ExecutiveLongTermIncentiveSharePlanMember_9f5223ec-0135-49a6-901f-9890b0d688cf" xlink:href="ntb-20201231.xsd#ntb_ExecutiveLongTermIncentiveSharePlanMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_b1207f34-7e73-4118-878c-fe56d215820f" xlink:to="loc_ntb_ExecutiveLongTermIncentiveSharePlanMember_9f5223ec-0135-49a6-901f-9890b0d688cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_ada05051-c3a5-40f4-bb56-78ce93dd4d97" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_86122dbf-66b8-4f47-b00b-1f23d41634ec" xlink:to="loc_us-gaap_AwardTypeAxis_ada05051-c3a5-40f4-bb56-78ce93dd4d97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_64fffdcb-a030-4dec-9eaf-41dd0026e17b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_ada05051-c3a5-40f4-bb56-78ce93dd4d97" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_64fffdcb-a030-4dec-9eaf-41dd0026e17b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_9c190fda-22b6-428d-b5df-5b3c6e5d8fb8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedStockMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_64fffdcb-a030-4dec-9eaf-41dd0026e17b" xlink:to="loc_us-gaap_RestrictedStockMember_9c190fda-22b6-428d-b5df-5b3c6e5d8fb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PerformanceSharesMember_b223dab6-43d6-40c8-b72c-900df6c21f70" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PerformanceSharesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_64fffdcb-a030-4dec-9eaf-41dd0026e17b" xlink:to="loc_us-gaap_PerformanceSharesMember_b223dab6-43d6-40c8-b72c-900df6c21f70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_51ed33e1-9635-41a6-8f39-6f591d6688d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_86122dbf-66b8-4f47-b00b-1f23d41634ec" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_51ed33e1-9635-41a6-8f39-6f591d6688d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedAbstract_8453bae8-f3a7-48f5-ba7a-96209f5067bf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_51ed33e1-9635-41a6-8f39-6f591d6688d7" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedAbstract_8453bae8-f3a7-48f5-ba7a-96209f5067bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_3c9501a2-fab8-4344-b647-2a36b4b854f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedAbstract_8453bae8-f3a7-48f5-ba7a-96209f5067bf" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_3c9501a2-fab8-4344-b647-2a36b4b854f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_1a7dc9e1-8c89-4ef6-9c2f-f036ff9dc4f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedAbstract_8453bae8-f3a7-48f5-ba7a-96209f5067bf" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_1a7dc9e1-8c89-4ef6-9c2f-f036ff9dc4f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_92b3433d-1b7d-4b0f-aa97-bf6d72b65f84" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedAbstract_8453bae8-f3a7-48f5-ba7a-96209f5067bf" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_92b3433d-1b7d-4b0f-aa97-bf6d72b65f84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Sharebuybackplans" xlink:type="simple" xlink:href="ntb-20201231.xsd#Sharebuybackplans"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Sharebuybackplans" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_ba194eda-2966-4da6-aad7-b9c102748a52" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_0d570c0b-3b9a-49a2-bf7a-ba7e282a38b3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_ba194eda-2966-4da6-aad7-b9c102748a52" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_0d570c0b-3b9a-49a2-bf7a-ba7e282a38b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebuybackplansTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebuybackplansTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebuybackplansTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_e3d0042a-813b-4b6d-859b-c382248303e4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfTreasuryStockByClassTextBlock_c14e8bee-7022-4b1a-8710-d67db7643352" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfTreasuryStockByClassTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_e3d0042a-813b-4b6d-859b-c382248303e4" xlink:to="loc_us-gaap_ScheduleOfTreasuryStockByClassTextBlock_c14e8bee-7022-4b1a-8710-d67db7643352" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SharebuybackplansDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SharebuybackplansDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SharebuybackplansDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_288ae5ce-f752-4840-a77d-a474b665e89e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_66f46015-c709-4db6-b789-1a5ff935f218" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_288ae5ce-f752-4840-a77d-a474b665e89e" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_66f46015-c709-4db6-b789-1a5ff935f218" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareRepurchaseProgramAxis_d06bc3d1-6c82-46f8-9b3c-8cd22bc3b4ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareRepurchaseProgramAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_66f46015-c709-4db6-b789-1a5ff935f218" xlink:to="loc_us-gaap_ShareRepurchaseProgramAxis_d06bc3d1-6c82-46f8-9b3c-8cd22bc3b4ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareRepurchaseProgramDomain_c51fdb70-4390-4b5a-8bd3-236de6f0dda9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareRepurchaseProgramDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramAxis_d06bc3d1-6c82-46f8-9b3c-8cd22bc3b4ef" xlink:to="loc_us-gaap_ShareRepurchaseProgramDomain_c51fdb70-4390-4b5a-8bd3-236de6f0dda9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TwoThousandEighteenCommonShareBuyBackProgramMember_3aaf1d6c-952b-4ffe-af9e-98bc8f520685" xlink:href="ntb-20201231.xsd#ntb_TwoThousandEighteenCommonShareBuyBackProgramMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramDomain_c51fdb70-4390-4b5a-8bd3-236de6f0dda9" xlink:to="loc_ntb_TwoThousandEighteenCommonShareBuyBackProgramMember_3aaf1d6c-952b-4ffe-af9e-98bc8f520685" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TwoThousandNineteenCommonShareBuyBackProgramMember_9e4e087a-3d54-4b68-9821-649eb8668081" xlink:href="ntb-20201231.xsd#ntb_TwoThousandNineteenCommonShareBuyBackProgramMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramDomain_c51fdb70-4390-4b5a-8bd3-236de6f0dda9" xlink:to="loc_ntb_TwoThousandNineteenCommonShareBuyBackProgramMember_9e4e087a-3d54-4b68-9821-649eb8668081" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TwoThousandTwentyOneCommonShareBuyBackProgramMember_453be2b1-19d4-4e6e-aad3-83285329d544" xlink:href="ntb-20201231.xsd#ntb_TwoThousandTwentyOneCommonShareBuyBackProgramMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramDomain_c51fdb70-4390-4b5a-8bd3-236de6f0dda9" xlink:to="loc_ntb_TwoThousandTwentyOneCommonShareBuyBackProgramMember_453be2b1-19d4-4e6e-aad3-83285329d544" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CommonShareBuyBackProgramMember_6f310dd5-cb38-4afe-a228-08a6b2803ab3" xlink:href="ntb-20201231.xsd#ntb_CommonShareBuyBackProgramMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramDomain_c51fdb70-4390-4b5a-8bd3-236de6f0dda9" xlink:to="loc_ntb_CommonShareBuyBackProgramMember_6f310dd5-cb38-4afe-a228-08a6b2803ab3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_31b41931-5cb7-429f-9f05-6d5e3a74bf03" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_66f46015-c709-4db6-b789-1a5ff935f218" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_31b41931-5cb7-429f-9f05-6d5e3a74bf03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_32409d80-5250-4533-858a-33bd60685036" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_31b41931-5cb7-429f-9f05-6d5e3a74bf03" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_32409d80-5250-4533-858a-33bd60685036" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_fea353e5-6696-46a5-81df-185b667dac1e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_32409d80-5250-4533-858a-33bd60685036" xlink:to="loc_us-gaap_SubsequentEventMember_fea353e5-6696-46a5-81df-185b667dac1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_8c63b5e6-824b-49c2-988e-799f43d8cdf5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_66f46015-c709-4db6-b789-1a5ff935f218" xlink:to="loc_us-gaap_ClassOfStockLineItems_8c63b5e6-824b-49c2-988e-799f43d8cdf5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramNumberOfSharesAuthorizedToBeRepurchased_64ca9d89-8990-4461-9c9a-896a33e42465" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchaseProgramNumberOfSharesAuthorizedToBeRepurchased"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_8c63b5e6-824b-49c2-988e-799f43d8cdf5" xlink:to="loc_us-gaap_StockRepurchaseProgramNumberOfSharesAuthorizedToBeRepurchased_64ca9d89-8990-4461-9c9a-896a33e42465" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_4b223635-88e7-4052-bb1a-fdb349426fd8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchaseProgramAuthorizedAmount1"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_8c63b5e6-824b-49c2-988e-799f43d8cdf5" xlink:to="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_4b223635-88e7-4052-bb1a-fdb349426fd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_2ef04f7c-0d9b-4e32-a847-b11407c44798" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockSharesAcquired"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_8c63b5e6-824b-49c2-988e-799f43d8cdf5" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_2ef04f7c-0d9b-4e32-a847-b11407c44798" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare_b8dc2ee7-6ffe-42cc-8e34-f801989d3528" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockAcquiredAverageCostPerShare"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_8c63b5e6-824b-49c2-988e-799f43d8cdf5" xlink:to="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare_b8dc2ee7-6ffe-42cc-8e34-f801989d3528" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_94a910ee-b670-467f-87f0-b196f4412e49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_8c63b5e6-824b-49c2-988e-799f43d8cdf5" xlink:to="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_94a910ee-b670-467f-87f0-b196f4412e49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Accumulatedothercomprehensiveloss" xlink:type="simple" xlink:href="ntb-20201231.xsd#Accumulatedothercomprehensiveloss"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Accumulatedothercomprehensiveloss" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_625315a6-9213-4e4f-a0cb-1f97113da221" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_6355f4f2-0bc5-45e1-a807-3806c95ac18a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNoteTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_625315a6-9213-4e4f-a0cb-1f97113da221" xlink:to="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_6355f4f2-0bc5-45e1-a807-3806c95ac18a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/AccumulatedothercomprehensivelossTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#AccumulatedothercomprehensivelossTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/AccumulatedothercomprehensivelossTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_64acd37f-efbd-4633-89d3-f7d263377b65" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_24f07e56-e565-4c9e-960a-bebb40e6e828" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_64acd37f-efbd-4633-89d3-f7d263377b65" xlink:to="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_24f07e56-e565-4c9e-960a-bebb40e6e828" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfComprehensiveIncomeLossTableTextBlock_5184165c-43e3-4059-b360-69bab1d55925" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfComprehensiveIncomeLossTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_64acd37f-efbd-4633-89d3-f7d263377b65" xlink:to="loc_us-gaap_ScheduleOfComprehensiveIncomeLossTableTextBlock_5184165c-43e3-4059-b360-69bab1d55925" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/AccumulatedothercomprehensivelossScheduleofAOCLComponentsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#AccumulatedothercomprehensivelossScheduleofAOCLComponentsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/AccumulatedothercomprehensivelossScheduleofAOCLComponentsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_ae4438e9-6840-4fb3-913e-fc15ebc53bdb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b661337b-e342-4a20-ba9c-93288915e0d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_ae4438e9-6840-4fb3-913e-fc15ebc53bdb" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b661337b-e342-4a20-ba9c-93288915e0d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_20e780ea-c077-4922-9067-fcf2d97a961d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b661337b-e342-4a20-ba9c-93288915e0d4" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_20e780ea-c077-4922-9067-fcf2d97a961d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_ca9c6865-ffe4-477c-805e-0d0d4a44385e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_20e780ea-c077-4922-9067-fcf2d97a961d" xlink:to="loc_us-gaap_EquityComponentDomain_ca9c6865-ffe4-477c-805e-0d0d4a44385e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_d06cdb44-6784-49db-8041-53bd1f848f54" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ca9c6865-ffe4-477c-805e-0d0d4a44385e" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_d06cdb44-6784-49db-8041-53bd1f848f54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_b8552133-2e31-412f-8588-04b392e65e0c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ca9c6865-ffe4-477c-805e-0d0d4a44385e" xlink:to="loc_us-gaap_AccumulatedNetUnrealizedInvestmentGainLossMember_b8552133-2e31-412f-8588-04b392e65e0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_afb1357d-5dc9-440d-bf42-946cf53b8e1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ca9c6865-ffe4-477c-805e-0d0d4a44385e" xlink:to="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_afb1357d-5dc9-440d-bf42-946cf53b8e1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_6a9ef1fa-0ccb-4e04-bb3c-630bbc97f9b5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ca9c6865-ffe4-477c-805e-0d0d4a44385e" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_6a9ef1fa-0ccb-4e04-bb3c-630bbc97f9b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InformationByCategoryOfDebtSecurityAxis_868cbdc8-6083-49d5-bd88-245b158e82ea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InformationByCategoryOfDebtSecurityAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b661337b-e342-4a20-ba9c-93288915e0d4" xlink:to="loc_us-gaap_InformationByCategoryOfDebtSecurityAxis_868cbdc8-6083-49d5-bd88-245b158e82ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_32bca91f-1701-484c-ada1-617f02c064a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InformationByCategoryOfDebtSecurityAxis_868cbdc8-6083-49d5-bd88-245b158e82ea" xlink:to="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_32bca91f-1701-484c-ada1-617f02c064a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldtomaturitySecuritiesMember_b7cde3b1-152b-485a-b70d-48a0346087f7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldtomaturitySecuritiesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_32bca91f-1701-484c-ada1-617f02c064a6" xlink:to="loc_us-gaap_HeldtomaturitySecuritiesMember_b7cde3b1-152b-485a-b70d-48a0346087f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableforsaleSecuritiesMember_9da9f1cf-2a2c-4f7a-b4b2-2fd29d4fa4ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableforsaleSecuritiesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_32bca91f-1701-484c-ada1-617f02c064a6" xlink:to="loc_us-gaap_AvailableforsaleSecuritiesMember_9da9f1cf-2a2c-4f7a-b4b2-2fd29d4fa4ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_072be558-de0f-4887-a9ad-b2ab51dfb5f7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b661337b-e342-4a20-ba9c-93288915e0d4" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_072be558-de0f-4887-a9ad-b2ab51dfb5f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_a8628359-721c-494c-9b8b-404db3b1b2b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_072be558-de0f-4887-a9ad-b2ab51dfb5f7" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_a8628359-721c-494c-9b8b-404db3b1b2b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_a81e5d20-821b-4a6d-9edc-b5a98578fbf0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_a8628359-721c-494c-9b8b-404db3b1b2b7" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_a81e5d20-821b-4a6d-9edc-b5a98578fbf0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_06ccb99e-1362-4566-9f3e-ef1779b9b4e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_a8628359-721c-494c-9b8b-404db3b1b2b7" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_06ccb99e-1362-4566-9f3e-ef1779b9b4e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_285f27ac-594e-4e3b-a341-e71b6dce9415" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b661337b-e342-4a20-ba9c-93288915e0d4" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_285f27ac-594e-4e3b-a341-e71b6dce9415" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTaxAbstract_d02aef2f-cb77-4f62-883f-a66359087ee0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTaxAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_285f27ac-594e-4e3b-a341-e71b6dce9415" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTaxAbstract_d02aef2f-cb77-4f62-883f-a66359087ee0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_82992173-a0e7-479a-b865-d9a3b4488fc9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTaxAbstract_d02aef2f-cb77-4f62-883f-a66359087ee0" xlink:to="loc_us-gaap_StockholdersEquity_82992173-a0e7-479a-b865-d9a3b4488fc9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_a60ddcc4-0dc0-49a2-ab8f-c26b73b33b35" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTaxAbstract_d02aef2f-cb77-4f62-883f-a66359087ee0" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_a60ddcc4-0dc0-49a2-ab8f-c26b73b33b35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_2c22a2e6-92a1-4cb7-ae64-66088d7214f5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTaxAbstract_d02aef2f-cb77-4f62-883f-a66359087ee0" xlink:to="loc_us-gaap_StockholdersEquity_2c22a2e6-92a1-4cb7-ae64-66088d7214f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/AccumulatedothercomprehensivelossNetChangeofAOCLComponentsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#AccumulatedothercomprehensivelossNetChangeofAOCLComponentsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/AccumulatedothercomprehensivelossNetChangeofAOCLComponentsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_593213ff-1776-4b5b-a395-480fd8c34346" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_6fe2785c-1416-4d05-8226-db445d7a9929" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_593213ff-1776-4b5b-a395-480fd8c34346" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_6fe2785c-1416-4d05-8226-db445d7a9929" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InformationByCategoryOfDebtSecurityAxis_fc60bb8a-5d46-4e0f-9dd5-5f352dfef8db" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InformationByCategoryOfDebtSecurityAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_6fe2785c-1416-4d05-8226-db445d7a9929" xlink:to="loc_us-gaap_InformationByCategoryOfDebtSecurityAxis_fc60bb8a-5d46-4e0f-9dd5-5f352dfef8db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_08d44805-e73b-480b-9519-928d1fbe277a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InformationByCategoryOfDebtSecurityAxis_fc60bb8a-5d46-4e0f-9dd5-5f352dfef8db" xlink:to="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_08d44805-e73b-480b-9519-928d1fbe277a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldtomaturitySecuritiesMember_3523d025-f93d-43fa-be8f-a92d6a51296c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldtomaturitySecuritiesMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_08d44805-e73b-480b-9519-928d1fbe277a" xlink:to="loc_us-gaap_HeldtomaturitySecuritiesMember_3523d025-f93d-43fa-be8f-a92d6a51296c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableforsaleSecuritiesMember_143d47da-636e-443e-878b-5f7b5415d0ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableforsaleSecuritiesMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsCategoriesOfInvestmentsDomain_08d44805-e73b-480b-9519-928d1fbe277a" xlink:to="loc_us-gaap_AvailableforsaleSecuritiesMember_143d47da-636e-443e-878b-5f7b5415d0ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_38bed87e-f602-4e7f-a9a7-6c45ecaf0b13" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_6fe2785c-1416-4d05-8226-db445d7a9929" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_38bed87e-f602-4e7f-a9a7-6c45ecaf0b13" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_3f88cb90-5d87-40b5-ba52-71f9d90cef63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_38bed87e-f602-4e7f-a9a7-6c45ecaf0b13" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_3f88cb90-5d87-40b5-ba52-71f9d90cef63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_a6d2fb2b-8115-45a6-b22d-ebcef6cfb108" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_3f88cb90-5d87-40b5-ba52-71f9d90cef63" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_a6d2fb2b-8115-45a6-b22d-ebcef6cfb108" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_ce7cc16d-4ba9-4057-ad51-3017dc849426" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_3f88cb90-5d87-40b5-ba52-71f9d90cef63" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_ce7cc16d-4ba9-4057-ad51-3017dc849426" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_25c3a372-b496-4ce9-801c-c23f45f8b25c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_6fe2785c-1416-4d05-8226-db445d7a9929" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_25c3a372-b496-4ce9-801c-c23f45f8b25c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract_c842fa70-0155-4200-87e2-0cde440a5244" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_25c3a372-b496-4ce9-801c-c23f45f8b25c" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract_c842fa70-0155-4200-87e2-0cde440a5244" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_94a9cb10-9ddd-4be3-b3de-83eac60c0919" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract_c842fa70-0155-4200-87e2-0cde440a5244" xlink:to="loc_ntb_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_94a9cb10-9ddd-4be3-b3de-83eac60c0919" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossAfterReclassificationAndTax_bbf7fa21-8bec-4c85-b1b1-0b95a384c61b" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossAfterReclassificationAndTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract_c842fa70-0155-4200-87e2-0cde440a5244" xlink:to="loc_ntb_OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossAfterReclassificationAndTax_bbf7fa21-8bec-4c85-b1b1-0b95a384c61b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax_fc4960fa-1ea5-4117-b9b0-db6ef94f49ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract_c842fa70-0155-4200-87e2-0cde440a5244" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax_fc4960fa-1ea5-4117-b9b0-db6ef94f49ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesForeignCurrencyTransactionAndTranslationAdjustmentAndNetInvestmentHedgeGainLossAfterReclassificationAndTax_c93216c5-1b7f-4a5f-bfe0-15622ee89d26" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesForeignCurrencyTransactionAndTranslationAdjustmentAndNetInvestmentHedgeGainLossAfterReclassificationAndTax"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract_c842fa70-0155-4200-87e2-0cde440a5244" xlink:to="loc_ntb_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesForeignCurrencyTransactionAndTranslationAdjustmentAndNetInvestmentHedgeGainLossAfterReclassificationAndTax_c93216c5-1b7f-4a5f-bfe0-15622ee89d26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesNetOfTax_107fe985-be3c-4cd8-a6e3-32d1c62e0e8f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesNetOfTax"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesNetOfTaxPeriodIncreaseDecreaseAbstract_c842fa70-0155-4200-87e2-0cde440a5244" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesNetOfTax_107fe985-be3c-4cd8-a6e3-32d1c62e0e8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTaxAbstract_0717d574-ff84-40e1-a65b-49d2e3da6c59" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTaxAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_25c3a372-b496-4ce9-801c-c23f45f8b25c" xlink:to="loc_ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTaxAbstract_0717d574-ff84-40e1-a65b-49d2e3da6c59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_9529f91f-e13f-4382-ab6f-971b1bd20f94" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTaxAbstract_0717d574-ff84-40e1-a65b-49d2e3da6c59" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_9529f91f-e13f-4382-ab6f-971b1bd20f94" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfMarketableSecuritiesNetOfTax_2e664df1-7990-41a9-8c94-0d702c646cc1" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfMarketableSecuritiesNetOfTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTaxAbstract_0717d574-ff84-40e1-a65b-49d2e3da6c59" xlink:to="loc_ntb_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfMarketableSecuritiesNetOfTax_2e664df1-7990-41a9-8c94-0d702c646cc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTax_d6f41ebf-38f2-4c4a-b080-1206f58feaea" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTaxAbstract_0717d574-ff84-40e1-a65b-49d2e3da6c59" xlink:to="loc_ntb_OtherComprehensiveIncomeLossMarketableSecuritiesAdjustmentNetOfTax_d6f41ebf-38f2-4c4a-b080-1206f58feaea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_25c3a372-b496-4ce9-801c-c23f45f8b25c" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeReclassificationAdjustmentsNetOfTax_8aff31cf-f4a1-4442-bf7a-9e3247f66dc7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeReclassificationAdjustmentsNetOfTax"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeReclassificationAdjustmentsNetOfTax_8aff31cf-f4a1-4442-bf7a-9e3247f66dc7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossFinalizationOfPensionAndNonPensionPostretirementPlanValuationNetOfTax_16532ecf-a086-4226-99a3-5916ebc2f337" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossFinalizationOfPensionAndNonPensionPostretirementPlanValuationNetOfTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossFinalizationOfPensionAndNonPensionPostretirementPlanValuationNetOfTax_16532ecf-a086-4226-99a3-5916ebc2f337" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansNetUnamortizedGainLossArisingDuringPeriodNetOfTax_132d39a1-d0a1-45ea-a1d4-e307df5160b5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansNetUnamortizedGainLossArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansNetUnamortizedGainLossArisingDuringPeriodNetOfTax_132d39a1-d0a1-45ea-a1d4-e307df5160b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostsCreditArisingDuringPeriodNetOfTax_1cc53d91-483e-424d-acc5-27f91d2b344e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostsCreditArisingDuringPeriodNetOfTax"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostsCreditArisingDuringPeriodNetOfTax_1cc53d91-483e-424d-acc5-27f91d2b344e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax_13a8fb9f-8b96-4b08-97ec-865cd401711b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax_13a8fb9f-8b96-4b08-97ec-865cd401711b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetTransitionAssetObligationNetOfTax_84d8df00-4c75-413a-8fb2-6e9a0a09e763" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetTransitionAssetObligationNetOfTax"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetTransitionAssetObligationNetOfTax_84d8df00-4c75-413a-8fb2-6e9a0a09e763" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditNetOfTax_5cf02c8f-a332-4c1e-829a-a81652c94422" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditNetOfTax"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditNetOfTax_5cf02c8f-a332-4c1e-829a-a81652c94422" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_b9c1d283-47ca-459b-86aa-a4bb0c1d12c2" xlink:href="ntb-20201231.xsd#ntb_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_ntb_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_b9c1d283-47ca-459b-86aa-a4bb0c1d12c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_caa86c36-e706-43bc-9b59-8ea22552b176" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_282c072a-0fda-47f4-93ba-56dc8b902679" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_caa86c36-e706-43bc-9b59-8ea22552b176" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_bf2179fa-c8d2-486e-b311-c17beec6750b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_25c3a372-b496-4ce9-801c-c23f45f8b25c" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_bf2179fa-c8d2-486e-b311-c17beec6750b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Capitalstructure" xlink:type="simple" xlink:href="ntb-20201231.xsd#Capitalstructure"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Capitalstructure" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_72b6a846-84cb-4f22-b6a5-59e9e640e188" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BankingAndThriftDisclosureTextBlock_4c238ef4-5706-4149-9c84-5a616cb97eb1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BankingAndThriftDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_72b6a846-84cb-4f22-b6a5-59e9e640e188" xlink:to="loc_us-gaap_BankingAndThriftDisclosureTextBlock_4c238ef4-5706-4149-9c84-5a616cb97eb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CapitalstructureTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#CapitalstructureTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CapitalstructureTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_152bb510-2a13-4a7e-b3d1-6059897b92b6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock_d085489d-2f62-4e32-9d02-c0d8fafa7089" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_152bb510-2a13-4a7e-b3d1-6059897b92b6" xlink:to="loc_us-gaap_ScheduleOfComplianceWithRegulatoryCapitalRequirementsUnderBankingRegulationsTextBlock_d085489d-2f62-4e32-9d02-c0d8fafa7089" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CapitalstructureAuthorizedCapitalDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CapitalstructureAuthorizedCapitalDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CapitalstructureAuthorizedCapitalDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_e794ac23-26be-4761-877a-3ee1d1647a61" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_aeea4532-6635-4cd4-b5d5-b50a3db8c9d2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_e794ac23-26be-4761-877a-3ee1d1647a61" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_aeea4532-6635-4cd4-b5d5-b50a3db8c9d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_fb75263e-b4e7-47f4-a66f-8c5f897d08d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_aeea4532-6635-4cd4-b5d5-b50a3db8c9d2" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_fb75263e-b4e7-47f4-a66f-8c5f897d08d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4f88b15c-c0c2-4256-a286-1c9028bd4bb9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_fb75263e-b4e7-47f4-a66f-8c5f897d08d6" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4f88b15c-c0c2-4256-a286-1c9028bd4bb9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IPOMember_f1b4b48f-a7fd-428c-a624-625a047284f4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IPOMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4f88b15c-c0c2-4256-a286-1c9028bd4bb9" xlink:to="loc_us-gaap_IPOMember_f1b4b48f-a7fd-428c-a624-625a047284f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NewlyIssuedMember_bc0dbb8c-25b0-4463-a887-22cac02b88a0" xlink:href="ntb-20201231.xsd#ntb_NewlyIssuedMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4f88b15c-c0c2-4256-a286-1c9028bd4bb9" xlink:to="loc_ntb_NewlyIssuedMember_bc0dbb8c-25b0-4463-a887-22cac02b88a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_SellingShareholdersMember_7662b6be-1e79-4f64-941a-ca16eff78841" xlink:href="ntb-20201231.xsd#ntb_SellingShareholdersMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4f88b15c-c0c2-4256-a286-1c9028bd4bb9" xlink:to="loc_ntb_SellingShareholdersMember_7662b6be-1e79-4f64-941a-ca16eff78841" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OverAllotmentOptionMember_9873f237-67f5-49aa-b44d-7b2a2787fda1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OverAllotmentOptionMember"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4f88b15c-c0c2-4256-a286-1c9028bd4bb9" xlink:to="loc_us-gaap_OverAllotmentOptionMember_9873f237-67f5-49aa-b44d-7b2a2787fda1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_633b43db-99d7-450d-99bf-45018f770648" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_aeea4532-6635-4cd4-b5d5-b50a3db8c9d2" xlink:to="loc_us-gaap_StatementClassOfStockAxis_633b43db-99d7-450d-99bf-45018f770648" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_2a29d20a-5263-46c0-b3b2-a4755e432862" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_633b43db-99d7-450d-99bf-45018f770648" xlink:to="loc_us-gaap_ClassOfStockDomain_2a29d20a-5263-46c0-b3b2-a4755e432862" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CommonStockIssuedAndCommonStockAuthorizedButUnissuedMember_60c5341e-625e-46a9-abc9-6d0d03952835" xlink:href="ntb-20201231.xsd#ntb_CommonStockIssuedAndCommonStockAuthorizedButUnissuedMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_2a29d20a-5263-46c0-b3b2-a4755e432862" xlink:to="loc_ntb_CommonStockIssuedAndCommonStockAuthorizedButUnissuedMember_60c5341e-625e-46a9-abc9-6d0d03952835" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonClassAMember_d68bdb13-6d73-4919-8f89-e23c05dfd6aa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonClassAMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_2a29d20a-5263-46c0-b3b2-a4755e432862" xlink:to="loc_us-gaap_CommonClassAMember_d68bdb13-6d73-4919-8f89-e23c05dfd6aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonvotingCommonStockMember_a11def3d-0f99-4ad4-af0e-76f4b1c7d03b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NonvotingCommonStockMember"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_2a29d20a-5263-46c0-b3b2-a4755e432862" xlink:to="loc_us-gaap_NonvotingCommonStockMember_a11def3d-0f99-4ad4-af0e-76f4b1c7d03b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CurrencyAxis_53d28e1c-1c8d-4802-a3dd-7c7b0ba136dd" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CurrencyAxis"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_aeea4532-6635-4cd4-b5d5-b50a3db8c9d2" xlink:to="loc_srt_CurrencyAxis_53d28e1c-1c8d-4802-a3dd-7c7b0ba136dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_currency_AllCurrenciesDomain_f06ee412-f15e-4012-a0c5-774d09143468" xlink:href="https://xbrl.sec.gov/currency/2020/currency-2020-01-31.xsd#currency_AllCurrenciesDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CurrencyAxis_53d28e1c-1c8d-4802-a3dd-7c7b0ba136dd" xlink:to="loc_currency_AllCurrenciesDomain_f06ee412-f15e-4012-a0c5-774d09143468" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_currency_USD_5d501588-0f4c-4329-a639-acbb9b71657d" xlink:href="https://xbrl.sec.gov/currency/2020/currency-2020-01-31.xsd#currency_USD"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currency_AllCurrenciesDomain_f06ee412-f15e-4012-a0c5-774d09143468" xlink:to="loc_currency_USD_5d501588-0f4c-4329-a639-acbb9b71657d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_currency_GBP_4245ee4b-de0d-41b1-8a79-037f0ba126d1" xlink:href="https://xbrl.sec.gov/currency/2020/currency-2020-01-31.xsd#currency_GBP"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_currency_AllCurrenciesDomain_f06ee412-f15e-4012-a0c5-774d09143468" xlink:to="loc_currency_GBP_4245ee4b-de0d-41b1-8a79-037f0ba126d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_0953fcd1-b601-4ed2-9395-3093cdf4d768" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockLineItems"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_aeea4532-6635-4cd4-b5d5-b50a3db8c9d2" xlink:to="loc_us-gaap_ClassOfStockLineItems_0953fcd1-b601-4ed2-9395-3093cdf4d768" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_e5dfc2a4-4b76-4582-b05b-5e9bb1428325" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0953fcd1-b601-4ed2-9395-3093cdf4d768" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_e5dfc2a4-4b76-4582-b05b-5e9bb1428325" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_e167ce2e-06c5-422f-a41a-5dd9007e4d7b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0953fcd1-b601-4ed2-9395-3093cdf4d768" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_e167ce2e-06c5-422f-a41a-5dd9007e4d7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_9a3350e6-d269-42b1-8bf8-dda6913fc8a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0953fcd1-b601-4ed2-9395-3093cdf4d768" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_9a3350e6-d269-42b1-8bf8-dda6913fc8a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_26db8d7d-b62a-41eb-acc8-dc88dccd0b64" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesAuthorized"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0953fcd1-b601-4ed2-9395-3093cdf4d768" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_26db8d7d-b62a-41eb-acc8-dc88dccd0b64" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_eface09d-5365-4edd-b2b3-3d8088835e35" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_0953fcd1-b601-4ed2-9395-3093cdf4d768" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_eface09d-5365-4edd-b2b3-3d8088835e35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CapitalstructureDividendsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CapitalstructureDividendsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CapitalstructureDividendsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_11ce6c63-f808-4941-adef-b7dd903caac4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_60b7a33f-0a30-4e12-9e76-bdebfec0e27e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_11ce6c63-f808-4941-adef-b7dd903caac4" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_60b7a33f-0a30-4e12-9e76-bdebfec0e27e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_a5a48da9-067d-4326-a285-78771fd778a0" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_60b7a33f-0a30-4e12-9e76-bdebfec0e27e" xlink:to="loc_srt_StatementScenarioAxis_a5a48da9-067d-4326-a285-78771fd778a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_e3532c55-8c0f-4de7-be7d-79d43da6a073" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementScenarioAxis_a5a48da9-067d-4326-a285-78771fd778a0" xlink:to="loc_srt_ScenarioUnspecifiedDomain_e3532c55-8c0f-4de7-be7d-79d43da6a073" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_b92cabf6-346e-46a2-8ec6-b162f2b6e134" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioForecastMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScenarioUnspecifiedDomain_e3532c55-8c0f-4de7-be7d-79d43da6a073" xlink:to="loc_srt_ScenarioForecastMember_b92cabf6-346e-46a2-8ec6-b162f2b6e134" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_503ffe1b-0d9e-4094-8d24-6e886cc7e675" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_60b7a33f-0a30-4e12-9e76-bdebfec0e27e" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_503ffe1b-0d9e-4094-8d24-6e886cc7e675" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_f11a132d-7c2d-4d1f-8a8b-a1cebf702e4b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_503ffe1b-0d9e-4094-8d24-6e886cc7e675" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_f11a132d-7c2d-4d1f-8a8b-a1cebf702e4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_167240e5-8762-4c58-bc62-b64a95c0ed6b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_f11a132d-7c2d-4d1f-8a8b-a1cebf702e4b" xlink:to="loc_us-gaap_SubsequentEventMember_167240e5-8762-4c58-bc62-b64a95c0ed6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_cca65c18-56a2-469c-9b17-336c6d1de3cd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_60b7a33f-0a30-4e12-9e76-bdebfec0e27e" xlink:to="loc_us-gaap_ClassOfStockLineItems_cca65c18-56a2-469c-9b17-336c6d1de3cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareDeclared_667b7ddb-8f40-46c7-a1ef-0ab8600567e4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockDividendsPerShareDeclared"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_cca65c18-56a2-469c-9b17-336c6d1de3cd" xlink:to="loc_us-gaap_CommonStockDividendsPerShareDeclared_667b7ddb-8f40-46c7-a1ef-0ab8600567e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareCashPaid_18a3bb80-100c-4fba-b9d7-38091b5bfb2e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockDividendsPerShareCashPaid"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_cca65c18-56a2-469c-9b17-336c6d1de3cd" xlink:to="loc_us-gaap_CommonStockDividendsPerShareCashPaid_18a3bb80-100c-4fba-b9d7-38091b5bfb2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CapitalstructureRegulatoryCapitalDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CapitalstructureRegulatoryCapitalDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CapitalstructureRegulatoryCapitalDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_511f4fc6-9fa2-4ae5-9d46-4bc9910289b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TierOneandTierTwoRiskBasedCapitalAbstract_8e272d4b-bfe0-4bb6-ac91-62b33c7ad631" xlink:href="ntb-20201231.xsd#ntb_TierOneandTierTwoRiskBasedCapitalAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_511f4fc6-9fa2-4ae5-9d46-4bc9910289b0" xlink:to="loc_ntb_TierOneandTierTwoRiskBasedCapitalAbstract_8e272d4b-bfe0-4bb6-ac91-62b33c7ad631" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TierOneCommonEquity_714011b7-3156-4984-9251-044cccaea937" xlink:href="ntb-20201231.xsd#ntb_TierOneCommonEquity"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TierOneandTierTwoRiskBasedCapitalAbstract_8e272d4b-bfe0-4bb6-ac91-62b33c7ad631" xlink:to="loc_ntb_TierOneCommonEquity_714011b7-3156-4984-9251-044cccaea937" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneRiskBasedCapital_41fffb85-b576-4dfc-9efa-ed64ead48a7d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TierOneRiskBasedCapital"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TierOneandTierTwoRiskBasedCapitalAbstract_8e272d4b-bfe0-4bb6-ac91-62b33c7ad631" xlink:to="loc_us-gaap_TierOneRiskBasedCapital_41fffb85-b576-4dfc-9efa-ed64ead48a7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierTwoRiskBasedCapital_eea9ec75-8a28-48cb-b71d-b0287df35445" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TierTwoRiskBasedCapital"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TierOneandTierTwoRiskBasedCapitalAbstract_8e272d4b-bfe0-4bb6-ac91-62b33c7ad631" xlink:to="loc_us-gaap_TierTwoRiskBasedCapital_eea9ec75-8a28-48cb-b71d-b0287df35445" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Capital_f54253b4-9a9e-460f-a3fd-e3ad079e76f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Capital"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_TierOneandTierTwoRiskBasedCapitalAbstract_8e272d4b-bfe0-4bb6-ac91-62b33c7ad631" xlink:to="loc_us-gaap_Capital_f54253b4-9a9e-460f-a3fd-e3ad079e76f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RiskWeightedAssets_c35b2e75-c124-4f77-86e2-7d1cb80b511e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RiskWeightedAssets"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_511f4fc6-9fa2-4ae5-9d46-4bc9910289b0" xlink:to="loc_us-gaap_RiskWeightedAssets_c35b2e75-c124-4f77-86e2-7d1cb80b511e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LeverageRatioExposureMeasure_da723cb3-08a0-4cf7-b2a4-e061af6bdcca" xlink:href="ntb-20201231.xsd#ntb_LeverageRatioExposureMeasure"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_511f4fc6-9fa2-4ae5-9d46-4bc9910289b0" xlink:to="loc_ntb_LeverageRatioExposureMeasure_da723cb3-08a0-4cf7-b2a4-e061af6bdcca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:href="ntb-20201231.xsd#ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_511f4fc6-9fa2-4ae5-9d46-4bc9910289b0" xlink:to="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TierOneCommonEquityRiskBasedCapitaltoRiskWeightedAssets_44da5f57-e516-445c-a5f6-5a358485beda" xlink:href="ntb-20201231.xsd#ntb_TierOneCommonEquityRiskBasedCapitaltoRiskWeightedAssets"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_ntb_TierOneCommonEquityRiskBasedCapitaltoRiskWeightedAssets_44da5f57-e516-445c-a5f6-5a358485beda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_TierOneCommonEquityRiskBasedCapitalRequiredforCapitalAdequacytoRiskWeightedAssets_26e738dc-bad6-4d53-acf2-d33c2db5a160" xlink:href="ntb-20201231.xsd#ntb_TierOneCommonEquityRiskBasedCapitalRequiredforCapitalAdequacytoRiskWeightedAssets"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_ntb_TierOneCommonEquityRiskBasedCapitalRequiredforCapitalAdequacytoRiskWeightedAssets_26e738dc-bad6-4d53-acf2-d33c2db5a160" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneRiskBasedCapitalToRiskWeightedAssets_96478ef5-24e1-4f52-a4d3-6da9e0751ee0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TierOneRiskBasedCapitalToRiskWeightedAssets"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_us-gaap_TierOneRiskBasedCapitalToRiskWeightedAssets_96478ef5-24e1-4f52-a4d3-6da9e0751ee0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssets_86b12b37-5c71-4a61-8162-d81228f76b98" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssets"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_us-gaap_TierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssets_86b12b37-5c71-4a61-8162-d81228f76b98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalToRiskWeightedAssets_3412ee6f-dc17-4317-9a03-4ebb98f3af04" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CapitalToRiskWeightedAssets"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_us-gaap_CapitalToRiskWeightedAssets_3412ee6f-dc17-4317-9a03-4ebb98f3af04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalRequiredForCapitalAdequacyToRiskWeightedAssets_69296eb4-04a7-47e9-a9af-7fc11b61f018" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CapitalRequiredForCapitalAdequacyToRiskWeightedAssets"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_us-gaap_CapitalRequiredForCapitalAdequacyToRiskWeightedAssets_69296eb4-04a7-47e9-a9af-7fc11b61f018" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneLeverageCapitalToAverageAssets_1b005205-1478-4313-b2c6-8994361b845d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TierOneLeverageCapitalToAverageAssets"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_us-gaap_TierOneLeverageCapitalToAverageAssets_1b005205-1478-4313-b2c6-8994361b845d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TierOneLeverageCapitalRequiredForCapitalAdequacyToAverageAssets_3e49622b-9fe5-44a5-b0f3-bb24d5f799bf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TierOneLeverageCapitalRequiredForCapitalAdequacyToAverageAssets"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_RiskBasedRatiosandLeverageRatiosAbstractAbstract_4440a77c-a4aa-4fd3-8c1f-e992b3fc6344" xlink:to="loc_us-gaap_TierOneLeverageCapitalRequiredForCapitalAdequacyToAverageAssets_3e49622b-9fe5-44a5-b0f3-bb24d5f799bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Incometaxes" xlink:type="simple" xlink:href="ntb-20201231.xsd#Incometaxes"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Incometaxes" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_b87f8528-ae73-49e1-9b9a-1d7d7a25a6ab" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_f9a94a3f-d517-4bbd-b877-354fe2cb2aeb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_b87f8528-ae73-49e1-9b9a-1d7d7a25a6ab" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_f9a94a3f-d517-4bbd-b877-354fe2cb2aeb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/IncometaxesTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#IncometaxesTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/IncometaxesTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_269aa4f0-9166-40cb-808d-6a66bbac1840" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_8ccae338-f1fa-4913-b29d-aa78667b047c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_269aa4f0-9166-40cb-808d-6a66bbac1840" xlink:to="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_8ccae338-f1fa-4913-b29d-aa78667b047c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_f8cffe44-67af-44d4-a104-2a02221e6830" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_269aa4f0-9166-40cb-808d-6a66bbac1840" xlink:to="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_f8cffe44-67af-44d4-a104-2a02221e6830" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_e36a8fcc-6343-4d8d-ae9a-8d497b2f365c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_269aa4f0-9166-40cb-808d-6a66bbac1840" xlink:to="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_e36a8fcc-6343-4d8d-ae9a-8d497b2f365c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/IncometaxesIncomeTaxesinConsolidatedStatementsofOperationsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#IncometaxesIncomeTaxesinConsolidatedStatementsofOperationsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/IncometaxesIncomeTaxesinConsolidatedStatementsofOperationsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_20c0369c-d254-4533-9b3a-431cdc4d98f4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_f2f66580-09e2-4a8c-852a-b652bba7b4bf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_20c0369c-d254-4533-9b3a-431cdc4d98f4" xlink:to="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_f2f66580-09e2-4a8c-852a-b652bba7b4bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_00b32a7f-a3fc-4784-8dee-399cf26eb47d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_20c0369c-d254-4533-9b3a-431cdc4d98f4" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_00b32a7f-a3fc-4784-8dee-399cf26eb47d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_d2b491b0-340b-4692-a63d-190b2a796468" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_20c0369c-d254-4533-9b3a-431cdc4d98f4" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_d2b491b0-340b-4692-a63d-190b2a796468" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/IncometaxesReconciliationbetweentheEffectiveIncomeTaxRateandtheStatutoryIncomeTaxRateDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#IncometaxesReconciliationbetweentheEffectiveIncomeTaxRateandtheStatutoryIncomeTaxRateDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/IncometaxesReconciliationbetweentheEffectiveIncomeTaxRateandtheStatutoryIncomeTaxRateDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_210aa1e7-e3b8-4220-b63c-344091fa4997" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_210aa1e7-e3b8-4220-b63c-344091fa4997" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_f75f2b20-8161-495c-9d75-9020a286569d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:to="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_f75f2b20-8161-495c-9d75-9020a286569d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpense_c2fe7f63-d244-410b-ba65-e9df33889d7f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpense"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpense_c2fe7f63-d244-410b-ba65-e9df33889d7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes_0b94cdc7-e6c2-4b34-97db-31a79cd1072f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:to="loc_us-gaap_IncomeTaxReconciliationPriorYearIncomeTaxes_0b94cdc7-e6c2-4b34-97db-31a79cd1072f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_0c549326-fba9-4312-8743-1a65102657fa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_0c549326-fba9-4312-8743-1a65102657fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_c02cf2de-2ada-4e17-aa2e-bff43aa67b1b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:to="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_c02cf2de-2ada-4e17-aa2e-bff43aa67b1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_ec62dca5-ffbf-4aff-9fe6-146bd08ab3bd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_0998043c-0c1e-4268-b938-d037757322a4" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_ec62dca5-ffbf-4aff-9fe6-146bd08ab3bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_210aa1e7-e3b8-4220-b63c-344091fa4997" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_83bbcc3e-c267-4573-812a-c7d5356a9f7d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_83bbcc3e-c267-4573-812a-c7d5356a9f7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpense_b602d074-e2cf-4016-a138-3fd929f377f3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpense"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpense_b602d074-e2cf-4016-a138-3fd929f377f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes_34ea27ee-c1e9-4526-9b0b-0eda2b254940" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes_34ea27ee-c1e9-4526-9b0b-0eda2b254940" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_8a418b25-a5a9-48a2-bc35-97324c19d82b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_8a418b25-a5a9-48a2-bc35-97324c19d82b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_7dfc21ce-2f66-420f-8cc3-9eddb703ab68" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_7dfc21ce-2f66-420f-8cc3-9eddb703ab68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_1f3ee77f-410d-4b47-8ffa-c64b84fc28a2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_19b2569d-e91b-43aa-96fa-2122168d5a32" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_1f3ee77f-410d-4b47-8ffa-c64b84fc28a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/IncometaxesDeferredIncomeTaxesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#IncometaxesDeferredIncomeTaxesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/IncometaxesDeferredIncomeTaxesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_68d61a37-1cfa-4d87-a871-3b8210867109" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsNetAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_68d61a37-1cfa-4d87-a871-3b8210867109" xlink:to="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsForeign_33e50650-9fa4-452b-aecd-a084617aa0cc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsForeign"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsForeign_33e50650-9fa4-452b-aecd-a084617aa0cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsPensions_ee861602-9592-490c-a710-25e24322ae76" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsPensions"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsPensions_ee861602-9592-490c-a710-25e24322ae76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment_2b3f22d4-cae0-4a49-906d-28c060c585b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:to="loc_us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment_2b3f22d4-cae0-4a49-906d-28c060c585b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsCompensatedAbsences_b21e155b-2aaa-4d24-9ba1-dbe6202585e7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsCompensatedAbsences"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsCompensatedAbsences_b21e155b-2aaa-4d24-9ba1-dbe6202585e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_c724636a-68ec-4e43-abca-64a1b5645787" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsGross"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:to="loc_us-gaap_DeferredTaxAssetsGross_c724636a-68ec-4e43-abca-64a1b5645787" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_8a8bb8c2-e110-4186-a5ff-956377dde838" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_8a8bb8c2-e110-4186-a5ff-956377dde838" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_7cc145cf-831e-4b48-9622-1cb60191bb3f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsNet"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxAssetsNetAbstract_131ea91b-4e1e-443d-bfa8-531ebc9ddfbc" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_7cc145cf-831e-4b48-9622-1cb60191bb3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesAbstract_d2b62b06-e417-49ac-a805-70ca2e5097d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxLiabilitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_68d61a37-1cfa-4d87-a871-3b8210867109" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesAbstract_d2b62b06-e417-49ac-a805-70ca2e5097d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesOther_634f0859-a54c-4143-93f8-f8606a682a00" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxLiabilitiesOther"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredTaxLiabilitiesAbstract_d2b62b06-e417-49ac-a805-70ca2e5097d4" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesOther_634f0859-a54c-4143-93f8-f8606a682a00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_f0072609-2263-44f2-b993-9bf001eeead3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_68d61a37-1cfa-4d87-a871-3b8210867109" xlink:to="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_f0072609-2263-44f2-b993-9bf001eeead3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/IncometaxesNarrativeDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#IncometaxesNarrativeDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/IncometaxesNarrativeDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_7e7db8f4-73ae-4674-ab27-b0ea9d87fc6f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwardsTable_dfb4fa3e-3f96-4894-a0e9-c3284b544076" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwardsTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7e7db8f4-73ae-4674-ab27-b0ea9d87fc6f" xlink:to="loc_us-gaap_OperatingLossCarryforwardsTable_dfb4fa3e-3f96-4894-a0e9-c3284b544076" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_3d493790-d547-4fdc-bb07-746114295ff4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_dfb4fa3e-3f96-4894-a0e9-c3284b544076" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_3d493790-d547-4fdc-bb07-746114295ff4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_69a8dfc2-cb8d-458f-b866-55eed8255102" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_3d493790-d547-4fdc-bb07-746114295ff4" xlink:to="loc_us-gaap_SegmentDomain_69a8dfc2-cb8d-458f-b866-55eed8255102" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_UnitedKingdomSegmentMember_73996863-70ed-4785-b8f5-8feb37898dfc" xlink:href="ntb-20201231.xsd#ntb_UnitedKingdomSegmentMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_69a8dfc2-cb8d-458f-b866-55eed8255102" xlink:to="loc_ntb_UnitedKingdomSegmentMember_73996863-70ed-4785-b8f5-8feb37898dfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_58853997-c4d4-4c2d-b815-f8decb45e7eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_dfb4fa3e-3f96-4894-a0e9-c3284b544076" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_58853997-c4d4-4c2d-b815-f8decb45e7eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_9a9a10ab-08a5-44cf-b2e1-3c861f8e7f94" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_58853997-c4d4-4c2d-b815-f8decb45e7eb" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_9a9a10ab-08a5-44cf-b2e1-3c861f8e7f94" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCountryMember_9f8418f6-d748-40b2-8028-c250f60da96e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignCountryMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_9a9a10ab-08a5-44cf-b2e1-3c861f8e7f94" xlink:to="loc_us-gaap_ForeignCountryMember_9f8418f6-d748-40b2-8028-c250f60da96e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwardsLineItems_a86e82c9-e5ff-4f10-9106-0d555dd58d47" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwardsLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_dfb4fa3e-3f96-4894-a0e9-c3284b544076" xlink:to="loc_us-gaap_OperatingLossCarryforwardsLineItems_a86e82c9-e5ff-4f10-9106-0d555dd58d47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_409f9153-c1c4-4d4e-9b37-8515889b97dd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_a86e82c9-e5ff-4f10-9106-0d555dd58d47" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_409f9153-c1c4-4d4e-9b37-8515889b97dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwards_57a954c0-a4ff-47fc-b635-a53ef13321f3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwards"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_a86e82c9-e5ff-4f10-9106-0d555dd58d47" xlink:to="loc_us-gaap_OperatingLossCarryforwards_57a954c0-a4ff-47fc-b635-a53ef13321f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OperatingLossCarryforwardsNoExpirationDate_9b3de2b2-6345-4dbc-821c-700a75394942" xlink:href="ntb-20201231.xsd#ntb_OperatingLossCarryforwardsNoExpirationDate"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_a86e82c9-e5ff-4f10-9106-0d555dd58d47" xlink:to="loc_ntb_OperatingLossCarryforwardsNoExpirationDate_9b3de2b2-6345-4dbc-821c-700a75394942" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Businesscombinations" xlink:type="simple" xlink:href="ntb-20201231.xsd#Businesscombinations"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Businesscombinations" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_b6a7ee31-49d6-47a0-b95f-ce8c6bf5b93b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationDisclosureTextBlock_d63f0ae8-d868-4ae2-a058-cfc05773fbd5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_b6a7ee31-49d6-47a0-b95f-ce8c6bf5b93b" xlink:to="loc_us-gaap_BusinessCombinationDisclosureTextBlock_d63f0ae8-d868-4ae2-a058-cfc05773fbd5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/BusinesscombinationsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#BusinesscombinationsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/BusinesscombinationsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_43886d76-68d7-4cff-8777-8b5b11490f8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTextBlock_89609202-3660-49d2-9d14-f47e572b86f1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_43886d76-68d7-4cff-8777-8b5b11490f8b" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTextBlock_89609202-3660-49d2-9d14-f47e572b86f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionProFormaInformationTextBlock_76bc999f-c4d0-4175-bd48-34ad1dab199c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionProFormaInformationTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_43886d76-68d7-4cff-8777-8b5b11490f8b" xlink:to="loc_us-gaap_BusinessAcquisitionProFormaInformationTextBlock_76bc999f-c4d0-4175-bd48-34ad1dab199c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/BusinesscombinationsDeutscheBanksGlobalTrustSolutionsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#BusinesscombinationsDeutscheBanksGlobalTrustSolutionsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/BusinesscombinationsDeutscheBanksGlobalTrustSolutionsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_573350ce-e9ea-49cc-8a6b-6b71d5decca9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_84c1e7a6-5d53-4314-931c-f8a610513539" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_573350ce-e9ea-49cc-8a6b-6b71d5decca9" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_84c1e7a6-5d53-4314-931c-f8a610513539" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_228ff289-5050-4713-abd4-f8a0195033b2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_84c1e7a6-5d53-4314-931c-f8a610513539" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_228ff289-5050-4713-abd4-f8a0195033b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0bfc0392-8b98-4eca-864c-c1293fdbef5c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_228ff289-5050-4713-abd4-f8a0195033b2" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0bfc0392-8b98-4eca-864c-c1293fdbef5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DeutscheBanksGlobalTrustSolutionsMember_76ee297c-272d-4139-90d1-b3f670966920" xlink:href="ntb-20201231.xsd#ntb_DeutscheBanksGlobalTrustSolutionsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0bfc0392-8b98-4eca-864c-c1293fdbef5c" xlink:to="loc_ntb_DeutscheBanksGlobalTrustSolutionsMember_76ee297c-272d-4139-90d1-b3f670966920" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_84c1e7a6-5d53-4314-931c-f8a610513539" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_bb2c1fd3-314b-4829-820b-d2e613e4ede9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_bb2c1fd3-314b-4829-820b-d2e613e4ede9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_8ac3792b-7b88-432a-a523-67a7bbed1ce6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_8ac3792b-7b88-432a-a523-67a7bbed1ce6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPreviousAcquisition_f591445b-fbf6-4a74-8003-83dcc7327fef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromPreviousAcquisition"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_us-gaap_ProceedsFromPreviousAcquisition_f591445b-fbf6-4a74-8003-83dcc7327fef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationTrustStructuresManagedAndAdministratedNumberOfStructures_1bf77e16-ca5b-4b15-80d5-d2bb4d403527" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationTrustStructuresManagedAndAdministratedNumberOfStructures"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_ntb_BusinessCombinationTrustStructuresManagedAndAdministratedNumberOfStructures_1bf77e16-ca5b-4b15-80d5-d2bb4d403527" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationTrustStructuresManagedAndAdministratedNumberOfPrivateClients_ee9de2ce-d00f-409e-9af4-ea0aea3781a4" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationTrustStructuresManagedAndAdministratedNumberOfPrivateClients"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_ntb_BusinessCombinationTrustStructuresManagedAndAdministratedNumberOfPrivateClients_ee9de2ce-d00f-409e-9af4-ea0aea3781a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_c1ec03bd-494c-4887-929c-1d0aafe9b854" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_c1ec03bd-494c-4887-929c-1d0aafe9b854" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts_4cacb503-be28-489c-82e1-cf3418fc6400" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts_4cacb503-be28-489c-82e1-cf3418fc6400" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessAcquisitionProFormaRevenueNonoperating_e05c6b1a-0e54-4e3a-9fd6-51bce1a75e5a" xlink:href="ntb-20201231.xsd#ntb_BusinessAcquisitionProFormaRevenueNonoperating"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_ntb_BusinessAcquisitionProFormaRevenueNonoperating_e05c6b1a-0e54-4e3a-9fd6-51bce1a75e5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationProFormaInformationEarningsorLossofAcquireesinceAcquisitionDateActualNonoperating_1bad5083-2db6-46db-83b9-a7b97013f5c8" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationProFormaInformationEarningsorLossofAcquireesinceAcquisitionDateActualNonoperating"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_6dd4daf1-0de7-4672-b39b-a11fa40734cc" xlink:to="loc_ntb_BusinessCombinationProFormaInformationEarningsorLossofAcquireesinceAcquisitionDateActualNonoperating_1bad5083-2db6-46db-83b9-a7b97013f5c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/BusinesscombinationsTotalConsiderationTransferredDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#BusinesscombinationsTotalConsiderationTransferredDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/BusinesscombinationsTotalConsiderationTransferredDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_0ae87363-aff3-4481-abb7-270acf5d781f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_f72e9b3e-1363-4fdb-aaf5-5bb25b367859" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_0ae87363-aff3-4481-abb7-270acf5d781f" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_f72e9b3e-1363-4fdb-aaf5-5bb25b367859" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_f5ef8286-7049-4401-a3a8-ace5c48b7f87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_f72e9b3e-1363-4fdb-aaf5-5bb25b367859" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_f5ef8286-7049-4401-a3a8-ace5c48b7f87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_e68cc50b-479d-4fbb-be4d-1109e14e54c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_f5ef8286-7049-4401-a3a8-ace5c48b7f87" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_e68cc50b-479d-4fbb-be4d-1109e14e54c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DeutscheBanksGlobalTrustSolutionsMember_86ae1dac-3540-4aa2-b116-69641ce713dd" xlink:href="ntb-20201231.xsd#ntb_DeutscheBanksGlobalTrustSolutionsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_e68cc50b-479d-4fbb-be4d-1109e14e54c5" xlink:to="loc_ntb_DeutscheBanksGlobalTrustSolutionsMember_86ae1dac-3540-4aa2-b116-69641ce713dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ABNAMROChannelIslandsLimitedAcquisitionMember_96c56411-4992-4984-874a-58e31fcf4dfd" xlink:href="ntb-20201231.xsd#ntb_ABNAMROChannelIslandsLimitedAcquisitionMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_e68cc50b-479d-4fbb-be4d-1109e14e54c5" xlink:to="loc_ntb_ABNAMROChannelIslandsLimitedAcquisitionMember_96c56411-4992-4984-874a-58e31fcf4dfd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_9a5637b7-35de-4793-b698-7b9279bb2ac1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_f72e9b3e-1363-4fdb-aaf5-5bb25b367859" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_9a5637b7-35de-4793-b698-7b9279bb2ac1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_85c677f5-6102-4540-940d-9184d6dcea32" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_9a5637b7-35de-4793-b698-7b9279bb2ac1" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_85c677f5-6102-4540-940d-9184d6dcea32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_cc5faf28-3795-4644-a533-9b0d69918374" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_9a5637b7-35de-4793-b698-7b9279bb2ac1" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_cc5faf28-3795-4644-a533-9b0d69918374" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_f78ecf21-e7c3-48de-b8d2-e41379920c34" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_cc5faf28-3795-4644-a533-9b0d69918374" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_f78ecf21-e7c3-48de-b8d2-e41379920c34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationrecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLoans_1b63829e-3b55-4b45-a570-ef1fb8cc023f" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationrecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLoans"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_cc5faf28-3795-4644-a533-9b0d69918374" xlink:to="loc_ntb_BusinessCombinationrecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLoans_1b63829e-3b55-4b45-a570-ef1fb8cc023f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_4ad1a7bd-344a-4006-b4e0-b7071c9480e3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_cc5faf28-3795-4644-a533-9b0d69918374" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_4ad1a7bd-344a-4006-b4e0-b7071c9480e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedOtherAssets_dc619d5e-fd62-4871-bce6-b6da0869b6d0" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedOtherAssets"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_cc5faf28-3795-4644-a533-9b0d69918374" xlink:to="loc_ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedOtherAssets_dc619d5e-fd62-4871-bce6-b6da0869b6d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_5b7108a0-30a7-4386-8c3f-d9f5e538a11e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_cc5faf28-3795-4644-a533-9b0d69918374" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_5b7108a0-30a7-4386-8c3f-d9f5e538a11e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract_a9acafaf-2c1a-42d6-ac75-48ef5209f984" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_9a5637b7-35de-4793-b698-7b9279bb2ac1" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract_a9acafaf-2c1a-42d6-ac75-48ef5209f984" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedDepositLiabilities_cd622108-c21b-43c8-b7b2-02a84fe4d935" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedDepositLiabilities"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract_a9acafaf-2c1a-42d6-ac75-48ef5209f984" xlink:to="loc_ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedDepositLiabilities_cd622108-c21b-43c8-b7b2-02a84fe4d935" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedOtherLiabilities_70cefd43-4c92-492a-9f51-5324eacf181e" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedOtherLiabilities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract_a9acafaf-2c1a-42d6-ac75-48ef5209f984" xlink:to="loc_ntb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedOtherLiabilities_70cefd43-4c92-492a-9f51-5324eacf181e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedNetLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_c77fc3dc-597b-454f-b6d9-0d57dfd7d735" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract_a9acafaf-2c1a-42d6-ac75-48ef5209f984" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_c77fc3dc-597b-454f-b6d9-0d57dfd7d735" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_58354f1a-a532-4a64-b6bc-cb9525c751e8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract_a9acafaf-2c1a-42d6-ac75-48ef5209f984" xlink:to="loc_us-gaap_Goodwill_58354f1a-a532-4a64-b6bc-cb9525c751e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_9f087470-e277-47b8-a9c2-0a355b9c1eb7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilitiesAbstract_a9acafaf-2c1a-42d6-ac75-48ef5209f984" xlink:to="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_9f087470-e277-47b8-a9c2-0a355b9c1eb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/BusinesscombinationsABNAMROChannelIslandsLimitedAcquisitionDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#BusinesscombinationsABNAMROChannelIslandsLimitedAcquisitionDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/BusinesscombinationsABNAMROChannelIslandsLimitedAcquisitionDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_97417056-6bac-485b-b993-2428ad38b17b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_02fc57e2-c9f4-4ce5-8994-51361da757d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_97417056-6bac-485b-b993-2428ad38b17b" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_02fc57e2-c9f4-4ce5-8994-51361da757d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_66d2892e-cb38-4aa6-a2cd-c12034450bc6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_02fc57e2-c9f4-4ce5-8994-51361da757d4" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_66d2892e-cb38-4aa6-a2cd-c12034450bc6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0bd6bd31-0d6e-41d7-9462-fd4d4aee7d81" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_66d2892e-cb38-4aa6-a2cd-c12034450bc6" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0bd6bd31-0d6e-41d7-9462-fd4d4aee7d81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ABNAMROChannelIslandsLimitedAcquisitionMember_4ef311c1-cb33-4502-a199-fbc33f30313f" xlink:href="ntb-20201231.xsd#ntb_ABNAMROChannelIslandsLimitedAcquisitionMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0bd6bd31-0d6e-41d7-9462-fd4d4aee7d81" xlink:to="loc_ntb_ABNAMROChannelIslandsLimitedAcquisitionMember_4ef311c1-cb33-4502-a199-fbc33f30313f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_bf49d9e3-ea67-4421-88c9-13b94a6f9bfe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_02fc57e2-c9f4-4ce5-8994-51361da757d4" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_bf49d9e3-ea67-4421-88c9-13b94a6f9bfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_f405c51e-3bc0-413a-9f22-08e269147cb4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_bf49d9e3-ea67-4421-88c9-13b94a6f9bfe" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_f405c51e-3bc0-413a-9f22-08e269147cb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerRelationshipsMember_d90eaca6-4305-486a-aa44-1e451e88239f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CustomerRelationshipsMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_f405c51e-3bc0-413a-9f22-08e269147cb4" xlink:to="loc_us-gaap_CustomerRelationshipsMember_d90eaca6-4305-486a-aa44-1e451e88239f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_02fc57e2-c9f4-4ce5-8994-51361da757d4" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_1c7f0584-2922-40a8-b6bf-4d2d60a1b9ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_1c7f0584-2922-40a8-b6bf-4d2d60a1b9ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustodyFees_81cb3d90-07b1-443a-a3a7-be01d912a17e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CustodyFees"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:to="loc_us-gaap_CustodyFees_81cb3d90-07b1-443a-a3a7-be01d912a17e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_e6135096-0db6-4705-a7b3-7a5cb6218833" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:to="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_e6135096-0db6-4705-a7b3-7a5cb6218833" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts_9eb1b8a0-bb98-4037-9c7e-0361681566cd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:to="loc_us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts_9eb1b8a0-bb98-4037-9c7e-0361681566cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessAcquisitionProFormaRevenueNonoperating_477593c5-d7f8-4369-b658-10b6022f7c5f" xlink:href="ntb-20201231.xsd#ntb_BusinessAcquisitionProFormaRevenueNonoperating"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:to="loc_ntb_BusinessAcquisitionProFormaRevenueNonoperating_477593c5-d7f8-4369-b658-10b6022f7c5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessCombinationProFormaInformationEarningsorLossofAcquireesinceAcquisitionDateActualNonoperating_d9037918-e860-4015-b050-6213051f5a4f" xlink:href="ntb-20201231.xsd#ntb_BusinessCombinationProFormaInformationEarningsorLossofAcquireesinceAcquisitionDateActualNonoperating"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_dd2d071e-1440-4ee6-b127-2fc9e2a87be9" xlink:to="loc_ntb_BusinessCombinationProFormaInformationEarningsorLossofAcquireesinceAcquisitionDateActualNonoperating_d9037918-e860-4015-b050-6213051f5a4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/BusinesscombinationsProFormaInformationDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#BusinesscombinationsProFormaInformationDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/BusinesscombinationsProFormaInformationDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_d219bee5-3912-4b10-846d-569c369a33c3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_53cdcccc-e190-40d1-b607-520aae0578b1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_d219bee5-3912-4b10-846d-569c369a33c3" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_53cdcccc-e190-40d1-b607-520aae0578b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_afec2c03-4723-426e-96ae-fa1746e7698b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_53cdcccc-e190-40d1-b607-520aae0578b1" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_afec2c03-4723-426e-96ae-fa1746e7698b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9fb76c1b-134c-48f5-9ec6-8fccc5eb81ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_afec2c03-4723-426e-96ae-fa1746e7698b" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9fb76c1b-134c-48f5-9ec6-8fccc5eb81ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_ABNAMROChannelIslandsLimitedAcquisitionMember_66a117fe-03aa-4ed1-85db-1375cc82b3f4" xlink:href="ntb-20201231.xsd#ntb_ABNAMROChannelIslandsLimitedAcquisitionMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9fb76c1b-134c-48f5-9ec6-8fccc5eb81ef" xlink:to="loc_ntb_ABNAMROChannelIslandsLimitedAcquisitionMember_66a117fe-03aa-4ed1-85db-1375cc82b3f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_65d89de5-36ef-42de-b4bb-cf49b39cb62a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_53cdcccc-e190-40d1-b607-520aae0578b1" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_65d89de5-36ef-42de-b4bb-cf49b39cb62a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionProFormaInformationAbstract_9c212569-5848-4fdd-a133-b3f9a9af83ab" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionProFormaInformationAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_65d89de5-36ef-42de-b4bb-cf49b39cb62a" xlink:to="loc_us-gaap_BusinessAcquisitionProFormaInformationAbstract_9c212569-5848-4fdd-a133-b3f9a9af83ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_deb65e4c-6d84-46ac-bfa6-36fdca30ecdc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionProFormaInformationAbstract_9c212569-5848-4fdd-a133-b3f9a9af83ab" xlink:to="loc_us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_deb65e4c-6d84-46ac-bfa6-36fdca30ecdc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BusinessAcquisitionProFormaNoninterestExpenseNonoperating_4aa98375-2257-48d1-a89c-2bd86afafd95" xlink:href="ntb-20201231.xsd#ntb_BusinessAcquisitionProFormaNoninterestExpenseNonoperating"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionProFormaInformationAbstract_9c212569-5848-4fdd-a133-b3f9a9af83ab" xlink:to="loc_ntb_BusinessAcquisitionProFormaNoninterestExpenseNonoperating_4aa98375-2257-48d1-a89c-2bd86afafd95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss_57dbdb06-fd4d-488d-b462-a188e08c7118" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionProFormaInformationAbstract_9c212569-5848-4fdd-a133-b3f9a9af83ab" xlink:to="loc_us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss_57dbdb06-fd4d-488d-b462-a188e08c7118" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Relatedpartytransactions" xlink:type="simple" xlink:href="ntb-20201231.xsd#Relatedpartytransactions"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Relatedpartytransactions" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_63800c07-2281-4d32-9a00-d6565f0c1163" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_f8b728ea-b0d7-43b9-8fd1-5e28ee78a31b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_63800c07-2281-4d32-9a00-d6565f0c1163" xlink:to="loc_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_f8b728ea-b0d7-43b9-8fd1-5e28ee78a31b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/RelatedpartytransactionsTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#RelatedpartytransactionsTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/RelatedpartytransactionsTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_284f084f-1939-4092-86f2-46f496e0fbe3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock_3e0daa5a-20af-437b-a573-2ab51511daf1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_284f084f-1939-4092-86f2-46f496e0fbe3" xlink:to="loc_us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock_3e0daa5a-20af-437b-a573-2ab51511daf1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/RelatedpartytransactionsFinancingTransactionsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#RelatedpartytransactionsFinancingTransactionsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/RelatedpartytransactionsFinancingTransactionsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_4445183a-3735-4774-95ae-c5732575e3cd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_c82cf25f-74ba-4b54-b6c4-b69a4c049833" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_4445183a-3735-4774-95ae-c5732575e3cd" xlink:to="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_c82cf25f-74ba-4b54-b6c4-b69a4c049833" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_4ff4ac9b-873d-4a61-9fce-3f1fb27a0d49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_c82cf25f-74ba-4b54-b6c4-b69a4c049833" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_4ff4ac9b-873d-4a61-9fce-3f1fb27a0d49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_72f5177b-dde9-4016-b32d-81c8b97aa3ff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_4ff4ac9b-873d-4a61-9fce-3f1fb27a0d49" xlink:to="loc_us-gaap_RelatedPartyDomain_72f5177b-dde9-4016-b32d-81c8b97aa3ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ManagementMember_e8d6f685-8321-49ce-bb78-baec24757ea4" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ManagementMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_72f5177b-dde9-4016-b32d-81c8b97aa3ff" xlink:to="loc_srt_ManagementMember_e8d6f685-8321-49ce-bb78-baec24757ea4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_AffiliatedEntityMember_2cc85278-077b-4cd1-a874-c244bff8ecf3" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_AffiliatedEntityMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_72f5177b-dde9-4016-b32d-81c8b97aa3ff" xlink:to="loc_srt_AffiliatedEntityMember_2cc85278-077b-4cd1-a874-c244bff8ecf3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_c82cf25f-74ba-4b54-b6c4-b69a4c049833" xlink:to="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesRollForward_e0640ef5-7972-4e83-968d-43db458805bd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoansAndLeasesReceivableRelatedPartiesRollForward"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:to="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesRollForward_e0640ef5-7972-4e83-968d-43db458805bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_a93ac2cf-316e-40d7-bbfe-259efde92983" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoansAndLeasesReceivableRelatedParties"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesRollForward_e0640ef5-7972-4e83-968d-43db458805bd" xlink:to="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_a93ac2cf-316e-40d7-bbfe-259efde92983" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesAdditions_6fd1a63a-7469-45cf-8626-aa9834b76da3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoansAndLeasesReceivableRelatedPartiesAdditions"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesRollForward_e0640ef5-7972-4e83-968d-43db458805bd" xlink:to="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesAdditions_6fd1a63a-7469-45cf-8626-aa9834b76da3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LoansAndLeasesReceivableRelatedPartiesProceedsAndEffectOfChangesInCompositionOfRelatedParties_60860f1c-7a36-4d52-989b-b6cdc250b748" xlink:href="ntb-20201231.xsd#ntb_LoansAndLeasesReceivableRelatedPartiesProceedsAndEffectOfChangesInCompositionOfRelatedParties"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesRollForward_e0640ef5-7972-4e83-968d-43db458805bd" xlink:to="loc_ntb_LoansAndLeasesReceivableRelatedPartiesProceedsAndEffectOfChangesInCompositionOfRelatedParties_60860f1c-7a36-4d52-989b-b6cdc250b748" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_67308c05-213a-40f6-9c3b-bc5465eb67d0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoansAndLeasesReceivableRelatedParties"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LoansAndLeasesReceivableRelatedPartiesRollForward_e0640ef5-7972-4e83-968d-43db458805bd" xlink:to="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_67308c05-213a-40f6-9c3b-bc5465eb67d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross_1cb26c2f-68de-4a90-abd2-29854e4dc9d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableGross"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:to="loc_us-gaap_NotesReceivableGross_1cb26c2f-68de-4a90-abd2-29854e4dc9d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Deposits_3d291d05-da7a-4fae-b210-c8b97a78981e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Deposits"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:to="loc_us-gaap_Deposits_3d291d05-da7a-4fae-b210-c8b97a78981e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_010d2735-c2c3-4d91-bfef-6003754a7d5f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndFeeIncomeLoansAndLeases"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_010d2735-c2c3-4d91-bfef-6003754a7d5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NoninterestIncomeOtherOperatingIncomeExpense_1daabb88-3f38-4352-9b6d-b13c2aa20422" xlink:href="ntb-20201231.xsd#ntb_NoninterestIncomeOtherOperatingIncomeExpense"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:to="loc_ntb_NoninterestIncomeOtherOperatingIncomeExpense_1daabb88-3f38-4352-9b6d-b13c2aa20422" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpense_467ce489-d1ae-4f79-a6ae-de8c6fa8ee7e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestExpense"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_ff42af00-019f-4548-8620-9a0c3c21824a" xlink:to="loc_us-gaap_NoninterestExpense_467ce489-d1ae-4f79-a6ae-de8c6fa8ee7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/RelatedpartytransactionsFinancialTransactionsWithRelatedPartiesDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#RelatedpartytransactionsFinancialTransactionsWithRelatedPartiesDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/RelatedpartytransactionsFinancialTransactionsWithRelatedPartiesDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_8e73badd-baea-4059-a28a-528f82054210" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_09ed7355-643e-4b8d-9a65-c66bb7ebaa4d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_8e73badd-baea-4059-a28a-528f82054210" xlink:to="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_09ed7355-643e-4b8d-9a65-c66bb7ebaa4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_0a1cd288-f36a-4fc0-8d7f-b3dd6eeb3443" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_09ed7355-643e-4b8d-9a65-c66bb7ebaa4d" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_0a1cd288-f36a-4fc0-8d7f-b3dd6eeb3443" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_511014ab-0560-4c4d-96d7-bdb223d543a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_0a1cd288-f36a-4fc0-8d7f-b3dd6eeb3443" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_511014ab-0560-4c4d-96d7-bdb223d543a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetManagementArrangementMember_8b8449bd-038f-48d7-985b-d12adb345429" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetManagementArrangementMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_511014ab-0560-4c4d-96d7-bdb223d543a1" xlink:to="loc_us-gaap_AssetManagementArrangementMember_8b8449bd-038f-48d7-985b-d12adb345429" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_9808a96f-1340-4f59-b6b5-71090fa70402" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_09ed7355-643e-4b8d-9a65-c66bb7ebaa4d" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_9808a96f-1340-4f59-b6b5-71090fa70402" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_a8171ba7-6cd2-4b10-9fbb-435801c9b3eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_9808a96f-1340-4f59-b6b5-71090fa70402" xlink:to="loc_us-gaap_RelatedPartyDomain_a8171ba7-6cd2-4b10-9fbb-435801c9b3eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_AffiliatedEntityMember_7016e74f-66d2-4dbf-b4a1-026672b4771a" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_AffiliatedEntityMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_a8171ba7-6cd2-4b10-9fbb-435801c9b3eb" xlink:to="loc_srt_AffiliatedEntityMember_7016e74f-66d2-4dbf-b4a1-026672b4771a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_09ed7355-643e-4b8d-9a65-c66bb7ebaa4d" xlink:to="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsFairValueDisclosureAbstract_75fdd072-b15c-402d-996d-effdc561bdce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsFairValueDisclosureAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:to="loc_us-gaap_InvestmentsFairValueDisclosureAbstract_75fdd072-b15c-402d-996d-effdc561bdce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_a08a0080-35fb-4eb0-837e-778fa7f6a8bb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsFairValueDisclosureAbstract_75fdd072-b15c-402d-996d-effdc561bdce" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_a08a0080-35fb-4eb0-837e-778fa7f6a8bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossOnInvestments_4b8bb864-bc41-4fba-b784-7b0edbccb24c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrealizedGainLossOnInvestments"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsFairValueDisclosureAbstract_75fdd072-b15c-402d-996d-effdc561bdce" xlink:to="loc_us-gaap_UnrealizedGainLossOnInvestments_4b8bb864-bc41-4fba-b784-7b0edbccb24c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross_2c84c6ef-8688-4929-b5c3-5db528da3779" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableGross"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:to="loc_us-gaap_NotesReceivableGross_2c84c6ef-8688-4929-b5c3-5db528da3779" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Deposits_879e6176-a23c-4372-9dc0-5a66e7a77cec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Deposits"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:to="loc_us-gaap_Deposits_879e6176-a23c-4372-9dc0-5a66e7a77cec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BrokerageCommissionsRevenue_7f7ff168-c87e-4593-863e-1fe210406ab1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BrokerageCommissionsRevenue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:to="loc_us-gaap_BrokerageCommissionsRevenue_7f7ff168-c87e-4593-863e-1fe210406ab1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CustodyandOtherAdministrationServicesRevenue_40381b2c-c5c3-4193-8194-244f98ed67e2" xlink:href="ntb-20201231.xsd#ntb_CustodyandOtherAdministrationServicesRevenue"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:to="loc_ntb_CustodyandOtherAdministrationServicesRevenue_40381b2c-c5c3-4193-8194-244f98ed67e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionOtherRevenuesFromTransactionsWithRelatedParty_72559207-4b88-45bd-8b8e-13d95ac0a3f6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionOtherRevenuesFromTransactionsWithRelatedParty"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_c9116ece-f81d-4f03-ad1b-5cf0410cfe34" xlink:to="loc_us-gaap_RelatedPartyTransactionOtherRevenuesFromTransactionsWithRelatedParty_72559207-4b88-45bd-8b8e-13d95ac0a3f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Condensedfinancialstatementsoftheparentcompanyonly" xlink:type="simple" xlink:href="ntb-20201231.xsd#Condensedfinancialstatementsoftheparentcompanyonly"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Condensedfinancialstatementsoftheparentcompanyonly" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_e35e1d39-0e52-46b2-ab83-3c0621a7668c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CondensedFinancialInformationOfParentCompanyOnlyDisclosureTextBlock_689ffd29-5443-485b-b9b4-fbaa223ec8d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CondensedFinancialInformationOfParentCompanyOnlyDisclosureTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_e35e1d39-0e52-46b2-ab83-3c0621a7668c" xlink:to="loc_us-gaap_CondensedFinancialInformationOfParentCompanyOnlyDisclosureTextBlock_689ffd29-5443-485b-b9b4-fbaa223ec8d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyTables" xlink:type="simple" xlink:href="ntb-20201231.xsd#CondensedfinancialstatementsoftheparentcompanyonlyTables"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyTables" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_3c093ed7-a2a4-481d-8a0a-29bc633c5f2b" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfCondensedBalanceSheetTableTextBlock_cd5a8d02-86a6-4c37-ba21-42509c907980" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScheduleOfCondensedBalanceSheetTableTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_3c093ed7-a2a4-481d-8a0a-29bc633c5f2b" xlink:to="loc_srt_ScheduleOfCondensedBalanceSheetTableTextBlock_cd5a8d02-86a6-4c37-ba21-42509c907980" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfCondensedIncomeStatementTableTextBlock_dd1414b0-2520-44c5-85f3-dd44694ffa0c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScheduleOfCondensedIncomeStatementTableTextBlock"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_3c093ed7-a2a4-481d-8a0a-29bc633c5f2b" xlink:to="loc_srt_ScheduleOfCondensedIncomeStatementTableTextBlock_dd1414b0-2520-44c5-85f3-dd44694ffa0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfCondensedCashFlowStatementTableTextBlock_f2c58595-5485-4ad6-abec-682baa3a1351" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScheduleOfCondensedCashFlowStatementTableTextBlock"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_3c093ed7-a2a4-481d-8a0a-29bc633c5f2b" xlink:to="loc_srt_ScheduleOfCondensedCashFlowStatementTableTextBlock_f2c58595-5485-4ad6-abec-682baa3a1351" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyCondensedBalanceSheetsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CondensedfinancialstatementsoftheparentcompanyonlyCondensedBalanceSheetsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyCondensedBalanceSheetsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_0a726629-a337-450f-b172-b5dc6577c81c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedBalanceSheetStatementTable_b236a47c-d55a-42a2-b8b9-44a1ab030e59" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedBalanceSheetStatementTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_0a726629-a337-450f-b172-b5dc6577c81c" xlink:to="loc_srt_CondensedBalanceSheetStatementTable_b236a47c-d55a-42a2-b8b9-44a1ab030e59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesAxis_a7655bb3-d92e-4250-a82e-9c748fd819e3" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementTable_b236a47c-d55a-42a2-b8b9-44a1ab030e59" xlink:to="loc_srt_ConsolidatedEntitiesAxis_a7655bb3-d92e-4250-a82e-9c748fd819e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesDomain_c1924e6f-475f-47cd-ab36-d26c67d8b651" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidatedEntitiesAxis_a7655bb3-d92e-4250-a82e-9c748fd819e3" xlink:to="loc_srt_ConsolidatedEntitiesDomain_c1924e6f-475f-47cd-ab36-d26c67d8b651" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ParentCompanyMember_051b9de2-8a1b-4a3f-aeb8-aa3c5d9303ee" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ParentCompanyMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidatedEntitiesDomain_c1924e6f-475f-47cd-ab36-d26c67d8b651" xlink:to="loc_srt_ParentCompanyMember_051b9de2-8a1b-4a3f-aeb8-aa3c5d9303ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_MajorCustomersAxis_ee3eeda5-54ad-4c18-b370-952ee054f3e1" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MajorCustomersAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementTable_b236a47c-d55a-42a2-b8b9-44a1ab030e59" xlink:to="loc_srt_MajorCustomersAxis_ee3eeda5-54ad-4c18-b370-952ee054f3e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_NameOfMajorCustomerDomain_c5c399bd-49cd-4297-8396-5da87674796f" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_NameOfMajorCustomerDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_ee3eeda5-54ad-4c18-b370-952ee054f3e1" xlink:to="loc_srt_NameOfMajorCustomerDomain_c5c399bd-49cd-4297-8396-5da87674796f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BanksMember_84d14d81-b1f0-48cd-81a7-a8efc4899fb4" xlink:href="ntb-20201231.xsd#ntb_BanksMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_c5c399bd-49cd-4297-8396-5da87674796f" xlink:to="loc_ntb_BanksMember_84d14d81-b1f0-48cd-81a7-a8efc4899fb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_IndividualCustomersMember_52e07a25-2444-4fc1-a432-02c9925024b3" xlink:href="ntb-20201231.xsd#ntb_IndividualCustomersMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_c5c399bd-49cd-4297-8396-5da87674796f" xlink:to="loc_ntb_IndividualCustomersMember_52e07a25-2444-4fc1-a432-02c9925024b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedBalanceSheetStatementsCaptionsLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementTable_b236a47c-d55a-42a2-b8b9-44a1ab030e59" xlink:to="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:to="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndDueFromBanks_a9cb0ffc-8f44-475d-a956-317366e6c9c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndDueFromBanks"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_CashAndDueFromBanks_a9cb0ffc-8f44-475d-a956-317366e6c9c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositsInBanks_fd4b42f1-d9b6-4076-8b45-e9d37265a0b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestBearingDepositsInBanks"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_InterestBearingDepositsInBanks_fd4b42f1-d9b6-4076-8b45-e9d37265a0b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashEquivalentsAtCarryingValue_eb270296-d362-413e-99ed-496abd811fb5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashEquivalentsAtCarryingValue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_CashEquivalentsAtCarryingValue_eb270296-d362-413e-99ed-496abd811fb5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_a89cf945-a3e6-4bbb-8365-98259f27a61d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_a89cf945-a3e6-4bbb-8365-98259f27a61d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuritiesPurchasedUnderAgreementsToResell_7b77ea45-9334-4c79-8b09-b6ca000967c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SecuritiesPurchasedUnderAgreementsToResell"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_SecuritiesPurchasedUnderAgreementsToResell_7b77ea45-9334-4c79-8b09-b6ca000967c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherShortTermInvestments_3c20251f-1408-4320-990d-3c9a8b5344ad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherShortTermInvestments"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_OtherShortTermInvestments_3c20251f-1408-4320-990d-3c9a8b5344ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecuritiesAbstract_f6724e8b-c12f-4556-b77b-4148d4170843" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketableSecuritiesAbstract"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_MarketableSecuritiesAbstract_f6724e8b-c12f-4556-b77b-4148d4170843" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_eab73537-78b4-454f-8989-90f186bf02f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNi"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_f6724e8b-c12f-4556-b77b-4148d4170843" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_eab73537-78b4-454f-8989-90f186bf02f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d2886d6d-0dd4-45fe-8fd2-74e4c3b2e03d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_f6724e8b-c12f-4556-b77b-4148d4170843" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d2886d6d-0dd4-45fe-8fd2-74e4c3b2e03d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecurities_fea3940b-55cf-495c-8f44-82af4615906d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecurities"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_f6724e8b-c12f-4556-b77b-4148d4170843" xlink:to="loc_us-gaap_HeldToMaturitySecurities_fea3940b-55cf-495c-8f44-82af4615906d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecurities_2f449479-c321-427b-8ba1-72eb3c417456" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketableSecurities"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MarketableSecuritiesAbstract_f6724e8b-c12f-4556-b77b-4148d4170843" xlink:to="loc_us-gaap_MarketableSecurities_2f449479-c321-427b-8ba1-72eb3c417456" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentsInSubsidiaries_3f17c4ca-5ac7-46a3-b776-c28623f63f83" xlink:href="ntb-20201231.xsd#ntb_InvestmentsInSubsidiaries"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_ntb_InvestmentsInSubsidiaries_3f17c4ca-5ac7-46a3-b776-c28623f63f83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableNet_54dc0d7c-497b-469f-a5a4-9eb27456d35c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableNet"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_NotesReceivableNet_54dc0d7c-497b-469f-a5a4-9eb27456d35c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableRelatedParties_02c64ada-c6bc-4cff-b296-2eb08a6753bc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesReceivableRelatedParties"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_NotesReceivableRelatedParties_02c64ada-c6bc-4cff-b296-2eb08a6753bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssets_128e2f22-2df2-45fc-b9e8-65f8a3d6bdcd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssets"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_OtherAssets_128e2f22-2df2-45fc-b9e8-65f8a3d6bdcd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_3256f88b-ff56-489f-bfd1-5fc43f33ad09" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_0ef13b8e-2677-46ac-a5be-17b32c3a13a8" xlink:to="loc_us-gaap_Assets_3256f88b-ff56-489f-bfd1-5fc43f33ad09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:to="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAbstract_a4b48b2f-c296-4947-93ca-ed370b08425b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:to="loc_us-gaap_DepositsAbstract_a4b48b2f-c296-4947-93ca-ed370b08425b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestBearingDepositLiabilities_ec03b179-0ee5-4241-a963-744ff581925d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestBearingDepositLiabilities"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsAbstract_a4b48b2f-c296-4947-93ca-ed370b08425b" xlink:to="loc_us-gaap_NoninterestBearingDepositLiabilities_ec03b179-0ee5-4241-a963-744ff581925d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositLiabilities_074e6dc1-4172-4224-8426-5a51f0e299fb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestBearingDepositLiabilities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DepositsAbstract_a4b48b2f-c296-4947-93ca-ed370b08425b" xlink:to="loc_us-gaap_InterestBearingDepositLiabilities_074e6dc1-4172-4224-8426-5a51f0e299fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Deposits_a2318dde-6e7c-4313-867a-e6de79b88e7f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Deposits"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:to="loc_us-gaap_Deposits_a2318dde-6e7c-4313-867a-e6de79b88e7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent_cc5e1e02-fd8a-4c84-a33a-5c99f66b8415" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesCurrentAndNoncurrent_cc5e1e02-fd8a-4c84-a33a-5c99f66b8415" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OtherLiabilitiesMiscellaneous_1d29b491-41a1-4df9-91e4-1f607d247056" xlink:href="ntb-20201231.xsd#ntb_OtherLiabilitiesMiscellaneous"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:to="loc_ntb_OtherLiabilitiesMiscellaneous_1d29b491-41a1-4df9-91e4-1f607d247056" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilities_98d4f867-54be-4d10-b0c5-e0fe35fb3caa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherLiabilities"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:to="loc_us-gaap_OtherLiabilities_98d4f867-54be-4d10-b0c5-e0fe35fb3caa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_2d4a5da7-8a4d-44c5-9d1d-007a9550d6cd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebt"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:to="loc_us-gaap_LongTermDebt_2d4a5da7-8a4d-44c5-9d1d-007a9550d6cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_4802de46-6caf-4227-bb8b-3c038c708bdb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Liabilities"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_aae52f58-5d36-49d9-a7b4-8fd3b874cc49" xlink:to="loc_us-gaap_Liabilities_4802de46-6caf-4227-bb8b-3c038c708bdb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_b242cf58-5bf6-4b4f-b2a2-a1a3883bc415" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:to="loc_us-gaap_StockholdersEquityAbstract_b242cf58-5bf6-4b4f-b2a2-a1a3883bc415" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_730b2b78-4ec6-44ab-89aa-9e01a7594940" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_b242cf58-5bf6-4b4f-b2a2-a1a3883bc415" xlink:to="loc_us-gaap_StockholdersEquity_730b2b78-4ec6-44ab-89aa-9e01a7594940" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_f407b9e4-cfbc-4a0c-8db2-46692c616dbb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_f407b9e4-cfbc-4a0c-8db2-46692c616dbb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_e6bc0e0f-edfe-4e85-a5d5-7f6a150689ea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_e6bc0e0f-edfe-4e85-a5d5-7f6a150689ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_057b3c5d-c7c0-4768-8797-992b25bfbf4f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HeldToMaturitySecuritiesFairValue"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedBalanceSheetStatementsCaptionsLineItems_1058136c-a4dd-44f7-afeb-2055bcddf474" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesFairValue_057b3c5d-c7c0-4768-8797-992b25bfbf4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyCondensedStatementsofOperationsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CondensedfinancialstatementsoftheparentcompanyonlyCondensedStatementsofOperationsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyCondensedStatementsofOperationsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_b4586ca3-e409-4579-9c25-73eb7f0ec6d6" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedIncomeStatementTable_dd42b00c-12cc-401b-9b33-7b56584003f8" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedIncomeStatementTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_b4586ca3-e409-4579-9c25-73eb7f0ec6d6" xlink:to="loc_srt_CondensedIncomeStatementTable_dd42b00c-12cc-401b-9b33-7b56584003f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesAxis_dd234a30-dbca-48d8-a251-dd186cc8a246" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementTable_dd42b00c-12cc-401b-9b33-7b56584003f8" xlink:to="loc_srt_ConsolidatedEntitiesAxis_dd234a30-dbca-48d8-a251-dd186cc8a246" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesDomain_a5bc0d95-e984-4f13-bc9e-c7572f11410f" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidatedEntitiesAxis_dd234a30-dbca-48d8-a251-dd186cc8a246" xlink:to="loc_srt_ConsolidatedEntitiesDomain_a5bc0d95-e984-4f13-bc9e-c7572f11410f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ParentCompanyMember_d42acbcf-5517-443c-8f58-7ae7fa13e18b" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ParentCompanyMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidatedEntitiesDomain_a5bc0d95-e984-4f13-bc9e-c7572f11410f" xlink:to="loc_srt_ParentCompanyMember_d42acbcf-5517-443c-8f58-7ae7fa13e18b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_MajorCustomersAxis_1ae426e0-5410-49b2-9a22-3163bcec8e3c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MajorCustomersAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementTable_dd42b00c-12cc-401b-9b33-7b56584003f8" xlink:to="loc_srt_MajorCustomersAxis_1ae426e0-5410-49b2-9a22-3163bcec8e3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_NameOfMajorCustomerDomain_353857ed-cb3f-4fd1-b7c5-111a70733030" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_NameOfMajorCustomerDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_1ae426e0-5410-49b2-9a22-3163bcec8e3c" xlink:to="loc_srt_NameOfMajorCustomerDomain_353857ed-cb3f-4fd1-b7c5-111a70733030" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BanksMember_d098fe33-cb97-435a-8911-c110b997eba7" xlink:href="ntb-20201231.xsd#ntb_BanksMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_353857ed-cb3f-4fd1-b7c5-111a70733030" xlink:to="loc_ntb_BanksMember_d098fe33-cb97-435a-8911-c110b997eba7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_IndividualCustomersMember_b643dc7a-290f-4fd9-93bf-a5ceaedea9cb" xlink:href="ntb-20201231.xsd#ntb_IndividualCustomersMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_353857ed-cb3f-4fd1-b7c5-111a70733030" xlink:to="loc_ntb_IndividualCustomersMember_b643dc7a-290f-4fd9-93bf-a5ceaedea9cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedIncomeStatementsCaptionsLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementTable_dd42b00c-12cc-401b-9b33-7b56584003f8" xlink:to="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:href="ntb-20201231.xsd#ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentBankingRevenue_a7407ed0-e415-48ec-a3db-0155133d1fe4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentBankingRevenue"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:to="loc_us-gaap_InvestmentBankingRevenue_a7407ed0-e415-48ec-a3db-0155133d1fe4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_fefce485-5991-4ea0-8a59-d9845a156a81" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_fefce485-5991-4ea0-8a59-d9845a156a81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_CustodyandOtherAdministrationServicesRevenue_d9abf7be-b1c4-410e-9bab-2fdf572a1234" xlink:href="ntb-20201231.xsd#ntb_CustodyandOtherAdministrationServicesRevenue"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:to="loc_ntb_CustodyandOtherAdministrationServicesRevenue_d9abf7be-b1c4-410e-9bab-2fdf572a1234" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestIncomeOther_c52970cc-5b73-4712-b19e-bbee5cb9f7ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestIncomeOther"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:to="loc_us-gaap_NoninterestIncomeOther_c52970cc-5b73-4712-b19e-bbee5cb9f7ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_DividendIncomeRelatedParties_85698cda-e301-4bed-ba04-d71a68f33b76" xlink:href="ntb-20201231.xsd#ntb_DividendIncomeRelatedParties"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:to="loc_ntb_DividendIncomeRelatedParties_85698cda-e301-4bed-ba04-d71a68f33b76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther_f0388d10-83a9-4e76-9824-9c03acd803db" xlink:href="ntb-20201231.xsd#ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOtherAbstract_7f54140a-b577-4bd3-ab2f-dfe57242b8d6" xlink:to="loc_ntb_InvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandOther_f0388d10-83a9-4e76-9824-9c03acd803db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_c8958396-adf9-449e-8698-1fc7f98115ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndDividendIncomeOperatingAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_c8958396-adf9-449e-8698-1fc7f98115ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_46e49bb8-6d06-4648-a3b3-585d7fc3c018" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndFeeIncomeLoansAndLeases"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_c8958396-adf9-449e-8698-1fc7f98115ef" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_46e49bb8-6d06-4648-a3b3-585d7fc3c018" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeSecurities_561674ae-7e8a-45b3-9c58-aa97956e67bd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndDividendIncomeSecurities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_c8958396-adf9-449e-8698-1fc7f98115ef" xlink:to="loc_us-gaap_InterestAndDividendIncomeSecurities_561674ae-7e8a-45b3-9c58-aa97956e67bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeDepositsWithFinancialInstitutions_effc6b2d-a525-4fed-b620-4bd2f5cdc334" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeDepositsWithFinancialInstitutions"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_c8958396-adf9-449e-8698-1fc7f98115ef" xlink:to="loc_us-gaap_InterestIncomeDepositsWithFinancialInstitutions_effc6b2d-a525-4fed-b620-4bd2f5cdc334" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating_8185aca0-da42-4f45-a1ec-61941aed1bd4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestAndDividendIncomeOperating"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperatingAbstract_c8958396-adf9-449e-8698-1fc7f98115ef" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperating_8185aca0-da42-4f45-a1ec-61941aed1bd4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseAbstract_c55d5309-47e2-47ac-9869-54175d8f73ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_InterestExpenseAbstract_c55d5309-47e2-47ac-9869-54175d8f73ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDeposits_ece1e50b-a386-43c6-9ed2-c8a3f38869c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseDeposits"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_c55d5309-47e2-47ac-9869-54175d8f73ee" xlink:to="loc_us-gaap_InterestExpenseDeposits_ece1e50b-a386-43c6-9ed2-c8a3f38869c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseLongTermDebt_eda93472-d647-4b6b-aa1c-af282725eba5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseLongTermDebt"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_c55d5309-47e2-47ac-9869-54175d8f73ee" xlink:to="loc_us-gaap_InterestExpenseLongTermDebt_eda93472-d647-4b6b-aa1c-af282725eba5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase_374147e3-d58b-4082-96b0-be3ceb1cab4e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_c55d5309-47e2-47ac-9869-54175d8f73ee" xlink:to="loc_us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase_374147e3-d58b-4082-96b0-be3ceb1cab4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_6f7e54f6-e9ee-4f0f-ac33-4b5c59fb52ac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpense"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InterestExpenseAbstract_c55d5309-47e2-47ac-9869-54175d8f73ee" xlink:to="loc_us-gaap_InterestExpense_6f7e54f6-e9ee-4f0f-ac33-4b5c59fb52ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_c04f30cc-2e30-4d25-acf9-a964bf133de1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseNet"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_c04f30cc-2e30-4d25-acf9-a964bf133de1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLossesExpensed_9fb67e1d-cc79-4d6f-acd1-779ba69ce8ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForLoanLossesExpensed"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_ProvisionForLoanLossesExpensed_9fb67e1d-cc79-4d6f-acd1-779ba69ce8ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_ffecc5e7-fd4d-4b55-b049-bca07cddecd7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_ffecc5e7-fd4d-4b55-b049-bca07cddecd7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiRealizedGainLoss_c7d00988-fc55-4ee5-b58b-ed3555ec895d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNiRealizedGainLoss"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_EquitySecuritiesFvNiRealizedGainLoss_c7d00988-fc55-4ee5-b58b-ed3555ec895d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_8372f13f-2a1d-4899-8c4a-2e0a705df362" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_8372f13f-2a1d-4899-8c4a-2e0a705df362" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_8b6aca2d-5e3a-45fa-9856-2b735b692e5c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnSalesOfOtherRealEstate"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_8b6aca2d-5e3a-45fa-9856-2b735b692e5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NoninterestIncomeOtherOperatingIncomeExpense_143fe526-9d86-44b2-91be-ccc95d34738a" xlink:href="ntb-20201231.xsd#ntb_NoninterestIncomeOtherOperatingIncomeExpense"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_ntb_NoninterestIncomeOtherOperatingIncomeExpense_143fe526-9d86-44b2-91be-ccc95d34738a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss_97597b59-0649-434c-89b2-686fd5cf2d5e" xlink:href="ntb-20201231.xsd#ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_ntb_NoninterestIncomeExcludingInvestmentBankingAdvisoryBrokerageandUnderwritingFeesandCommissionsandForeignCurrencyTransactionGainLoss_97597b59-0649-434c-89b2-686fd5cf2d5e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_1e07c318-518f-4e26-9ef7-98dc1f4d3669" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Revenues"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_Revenues_1e07c318-518f-4e26-9ef7-98dc1f4d3669" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestExpenseAbstract"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LaborAndRelatedExpense_f2c8df07-265f-45a5-9115-f1f37b69777c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LaborAndRelatedExpense"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_LaborAndRelatedExpense_f2c8df07-265f-45a5-9115-f1f37b69777c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommunicationsAndInformationTechnology_09bdea36-2bac-4894-ac14-e6c54c56968f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommunicationsAndInformationTechnology"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_CommunicationsAndInformationTechnology_09bdea36-2bac-4894-ac14-e6c54c56968f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProfessionalFees_ee90edcd-ff92-45a8-acfb-012f88d0dff5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProfessionalFees"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_ProfessionalFees_ee90edcd-ff92-45a8-acfb-012f88d0dff5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OccupancyNet_79b9ae1e-118d-4173-a3a4-a479a55527f6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OccupancyNet"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_OccupancyNet_79b9ae1e-118d-4173-a3a4-a479a55527f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxesExcludingIncomeAndExciseTaxes_ae706e1c-471f-4c5a-a79b-86510454eaed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxesExcludingIncomeAndExciseTaxes"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_TaxesExcludingIncomeAndExciseTaxes_ae706e1c-471f-4c5a-a79b-86510454eaed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponent_88ffc0e0-58dd-4015-9ddb-01034e311909" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponent"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_NetPeriodicDefinedBenefitsExpenseReversalOfExpenseExcludingServiceCostComponent_88ffc0e0-58dd-4015-9ddb-01034e311909" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingExpense_fa4a0f51-e8dd-4e51-9738-f01f9d3f5e53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketingExpense"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_MarketingExpense_fa4a0f51-e8dd-4e51-9738-f01f9d3f5e53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_89adce8f-4620-4556-867d-78fbd938ce8a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_89adce8f-4620-4556-867d-78fbd938ce8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoninterestExpense_2460e3f8-7390-4ecd-89f6-a96582fc1bf5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNoninterestExpense"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_OtherNoninterestExpense_2460e3f8-7390-4ecd-89f6-a96582fc1bf5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpense_4bd1ee5b-c931-4693-848e-8403e2c506b6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoninterestExpense"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoninterestExpenseAbstract_45472878-03c7-40e2-b615-810c51b87529" xlink:to="loc_us-gaap_NoninterestExpense_4bd1ee5b-c931-4693-848e-8403e2c506b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_IncomeLossfromContinuingOperationsbeforeIncomeLossFromSubsidiariesNetofTax_e18c3f74-3b5b-4991-baea-9964b5e0a595" xlink:href="ntb-20201231.xsd#ntb_IncomeLossfromContinuingOperationsbeforeIncomeLossFromSubsidiariesNetofTax"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_ntb_IncomeLossfromContinuingOperationsbeforeIncomeLossFromSubsidiariesNetofTax_e18c3f74-3b5b-4991-baea-9964b5e0a595" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromSubsidiariesNetOfTax_afa09b8c-d831-48cc-bfa4-be705ed0a22e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromSubsidiariesNetOfTax"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_IncomeLossFromSubsidiariesNetOfTax_afa09b8c-d831-48cc-bfa4-be705ed0a22e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_a13e1211-60f5-486a-aa55-15142f83e62b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_NetIncomeLoss_a13e1211-60f5-486a-aa55-15142f83e62b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_eabea9b0-a088-45a5-a89e-c5c686ec5111" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>

<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_eabea9b0-a088-45a5-a89e-c5c686ec5111" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_f43fe431-8798-4314-b639-b7f850049849" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>

<link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedIncomeStatementsCaptionsLineItems_cb8bb9e9-b080-4dca-9683-49f2b6bfbfa2" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_f43fe431-8798-4314-b639-b7f850049849" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyCondensedStatementsofCashFlowsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#CondensedfinancialstatementsoftheparentcompanyonlyCondensedStatementsofCashFlowsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/CondensedfinancialstatementsoftheparentcompanyonlyCondensedStatementsofCashFlowsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_9068a6d7-2b4c-4b7e-806d-1143f85197a4" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedCashFlowStatementTable_842fd804-b1df-441e-a41e-974075afcd7e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedCashFlowStatementTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedFinancialInformationOfParentCompanyOnlyDisclosureAbstract_9068a6d7-2b4c-4b7e-806d-1143f85197a4" xlink:to="loc_srt_CondensedCashFlowStatementTable_842fd804-b1df-441e-a41e-974075afcd7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesAxis_d176e123-9752-4b90-af2d-2cc00f01334c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementTable_842fd804-b1df-441e-a41e-974075afcd7e" xlink:to="loc_srt_ConsolidatedEntitiesAxis_d176e123-9752-4b90-af2d-2cc00f01334c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidatedEntitiesDomain_40699d35-9ab3-430b-8c1c-5310c8213190" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidatedEntitiesAxis_d176e123-9752-4b90-af2d-2cc00f01334c" xlink:to="loc_srt_ConsolidatedEntitiesDomain_40699d35-9ab3-430b-8c1c-5310c8213190" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ParentCompanyMember_72344f3d-7a63-4360-9b3c-9e961fc2169b" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ParentCompanyMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidatedEntitiesDomain_40699d35-9ab3-430b-8c1c-5310c8213190" xlink:to="loc_srt_ParentCompanyMember_72344f3d-7a63-4360-9b3c-9e961fc2169b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_MajorCustomersAxis_bcb5a242-4e30-4d3e-a25e-e5fb817f05e1" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MajorCustomersAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementTable_842fd804-b1df-441e-a41e-974075afcd7e" xlink:to="loc_srt_MajorCustomersAxis_bcb5a242-4e30-4d3e-a25e-e5fb817f05e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_NameOfMajorCustomerDomain_09b5097c-9e6d-44a9-be13-387eb771d7aa" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_NameOfMajorCustomerDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_bcb5a242-4e30-4d3e-a25e-e5fb817f05e1" xlink:to="loc_srt_NameOfMajorCustomerDomain_09b5097c-9e6d-44a9-be13-387eb771d7aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_BanksMember_6b5135ef-2782-4890-9776-13619e3be581" xlink:href="ntb-20201231.xsd#ntb_BanksMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_09b5097c-9e6d-44a9-be13-387eb771d7aa" xlink:to="loc_ntb_BanksMember_6b5135ef-2782-4890-9776-13619e3be581" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_IndividualCustomersMember_8c1f78fd-e81f-4180-856f-f76afb2ddeac" xlink:href="ntb-20201231.xsd#ntb_IndividualCustomersMember"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_09b5097c-9e6d-44a9-be13-387eb771d7aa" xlink:to="loc_ntb_IndividualCustomersMember_8c1f78fd-e81f-4180-856f-f76afb2ddeac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CondensedCashFlowStatementsCaptionsLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementTable_842fd804-b1df-441e-a41e-974075afcd7e" xlink:to="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_dc3cb52f-cde0-4124-9438-0f95d55544ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_dc3cb52f-cde0-4124-9438-0f95d55544ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_0e306cd6-c928-4430-857d-50cdc36c9cb6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_dc3cb52f-cde0-4124-9438-0f95d55544ce" xlink:to="loc_us-gaap_NetIncomeLoss_0e306cd6-c928-4430-857d-50cdc36c9cb6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_dc3cb52f-cde0-4124-9438-0f95d55544ce" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationAmortizationAndAccretionNet_4e462fba-21fd-4d1d-ace2-a3e5e40a667a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationAmortizationAndAccretionNet"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_DepreciationAmortizationAndAccretionNet_4e462fba-21fd-4d1d-ace2-a3e5e40a667a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLossesExpensed_5d938d48-f149-4b3e-a7e3-f72de72c7fc3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForLoanLossesExpensed"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_ProvisionForLoanLossesExpensed_5d938d48-f149-4b3e-a7e3-f72de72c7fc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_4b7484e3-2913-448c-8e8b-3a6dd7eac285" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensation"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_ShareBasedCompensation_4b7484e3-2913-448c-8e8b-3a6dd7eac285" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PaymentsToAcquireDebtAndEquitySecuritiesFVNIHeldforinvestment_2a61c851-97a2-491f-b5e2-0843baab8aba" xlink:href="ntb-20201231.xsd#ntb_PaymentsToAcquireDebtAndEquitySecuritiesFVNIHeldforinvestment"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_ntb_PaymentsToAcquireDebtAndEquitySecuritiesFVNIHeldforinvestment_2a61c851-97a2-491f-b5e2-0843baab8aba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfTradingSecuritiesHeldforinvestment_c3b9479a-8a7b-42c7-8496-b9bfe30c0c6f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfTradingSecuritiesHeldforinvestment"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_ProceedsFromSaleOfTradingSecuritiesHeldforinvestment_c3b9479a-8a7b-42c7-8496-b9bfe30c0c6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_85535253-71c2-4ef8-8043-7b9638d3b59d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLossExcludingOtherThanTemporaryImpairment_85535253-71c2-4ef8-8043-7b9638d3b59d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_dd3f5839-fb7a-4e94-8b34-792d9f3e672a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnSalesOfOtherRealEstate"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_dd3f5839-fb7a-4e94-8b34-792d9f3e672a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_5214c6e1-9e74-45cc-b363-021a25e58e58" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_5214c6e1-9e74-45cc-b363-021a25e58e58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_927f834c-f075-49a5-b38b-a954d04f96c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityMethodInvestmentDividendsOrDistributions"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_927f834c-f075-49a5-b38b-a954d04f96c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromSubsidiariesNetOfTax_8d6b7a1a-6c4a-4c80-b67e-48569ee6f90a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromSubsidiariesNetOfTax"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_IncomeLossFromSubsidiariesNetOfTax_8d6b7a1a-6c4a-4c80-b67e-48569ee6f90a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_0ff50da0-fba2-46f5-9c17-4215755f11a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6eec5336-2c09-42c3-83e0-3b6047d96be6" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_0ff50da0-fba2-46f5-9c17-4215755f11a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_27e4e2f2-94a5-4223-b1ae-3b4debcbff83" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_0ff50da0-fba2-46f5-9c17-4215755f11a3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_27e4e2f2-94a5-4223-b1ae-3b4debcbff83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_IncreaseDecreaseInEmployeeBenefitPlansInterestPayableNetAndOtherLiabilities_efb0b24c-caa9-45b2-a7fd-f2006fc6a44c" xlink:href="ntb-20201231.xsd#ntb_IncreaseDecreaseInEmployeeBenefitPlansInterestPayableNetAndOtherLiabilities"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_0ff50da0-fba2-46f5-9c17-4215755f11a3" xlink:to="loc_ntb_IncreaseDecreaseInEmployeeBenefitPlansInterestPayableNetAndOtherLiabilities_efb0b24c-caa9-45b2-a7fd-f2006fc6a44c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_764c2a33-5ba6-4a71-bebb-4f8da4d6b9bc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_dc3cb52f-cde0-4124-9438-0f95d55544ce" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_764c2a33-5ba6-4a71-bebb-4f8da4d6b9bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForSecuritiesPurchasedUnderAgreementsToResell_3ddde842-32c9-4df8-ab58-dbf21d1c897e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForSecuritiesPurchasedUnderAgreementsToResell"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_PaymentsForSecuritiesPurchasedUnderAgreementsToResell_3ddde842-32c9-4df8-ab58-dbf21d1c897e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments_433b713a-af84-4ae8-a1c5-c80105ae874d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments_433b713a-af84-4ae8-a1c5-c80105ae874d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireShortTermInvestments_2d958b6c-45b6-40d4-b4b9-715ce737d8c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireShortTermInvestments"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_PaymentsToAcquireShortTermInvestments_2d958b6c-45b6-40d4-b4b9-715ce737d8c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_f9bea78a-807f-4c59-b18e-a7fdc8ea282d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_f9bea78a-807f-4c59-b18e-a7fdc8ea282d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_087e7b47-fb06-4bcb-96d4-110002b3a47d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_087e7b47-fb06-4bcb-96d4-110002b3a47d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_9e4eec5c-3ddd-4d48-989f-fffa3f073ceb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_9e4eec5c-3ddd-4d48-989f-fffa3f073ceb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_8b78e20c-9541-4f6c-8055-25b6918607e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_8b78e20c-9541-4f6c-8055-25b6918607e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_7e76eef2-e851-4195-ba43-d99aa14d735d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireHeldToMaturitySecurities"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_7e76eef2-e851-4195-ba43-d99aa14d735d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromLoansReceivable_80facdc4-ac9e-4fa6-9c35-ff7e8285de2c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForProceedsFromLoansReceivable"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_PaymentsForProceedsFromLoansReceivable_80facdc4-ac9e-4fa6-9c35-ff7e8285de2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_OriginationRepaymentOfNotesReceivableFromRelatedParties_888d3411-95e1-4c4c-8759-72c078d65b18" xlink:href="ntb-20201231.xsd#ntb_OriginationRepaymentOfNotesReceivableFromRelatedParties"/>

<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_ntb_OriginationRepaymentOfNotesReceivableFromRelatedParties_888d3411-95e1-4c4c-8759-72c078d65b18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_PaymentsToAcquirePropertyPlantEquipmentAndSoftware_17344008-a85b-4237-ac71-c4b751c830bf" xlink:href="ntb-20201231.xsd#ntb_PaymentsToAcquirePropertyPlantEquipmentAndSoftware"/>

<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_ntb_PaymentsToAcquirePropertyPlantEquipmentAndSoftware_17344008-a85b-4237-ac71-c4b751c830bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfOtherRealEstate_d2b06bb4-ad94-42f1-ad54-0c66efa40b55" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfOtherRealEstate"/>

<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_ProceedsFromSaleOfOtherRealEstate_d2b06bb4-ad94-42f1-ad54-0c66efa40b55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates_127d83c2-22fa-4174-b9c9-bcf1b6f44e14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates"/>

<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates_127d83c2-22fa-4174-b9c9-bcf1b6f44e14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinessesAndInterestsInAffiliates_90f195e2-47a3-470c-bacd-9b9fb05fa621" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinessesAndInterestsInAffiliates"/>

<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinessesAndInterestsInAffiliates_90f195e2-47a3-470c-bacd-9b9fb05fa621" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_c69e0050-9e8d-4022-a519-eb953c2de6dc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>

<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_3c552994-f9f5-41a9-b28d-c537a07e8666" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_c69e0050-9e8d-4022-a519-eb953c2de6dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInDeposits_d8145c5b-a77b-4f14-80ad-2594c2b63e4d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInDeposits"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:to="loc_us-gaap_IncreaseDecreaseInDeposits_d8145c5b-a77b-4f14-80ad-2594c2b63e4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSubordinatedLongTermDebt_a0bc5d47-10b3-41cb-aef8-9ca5ed5832cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfSubordinatedLongTermDebt"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSubordinatedLongTermDebt_a0bc5d47-10b3-41cb-aef8-9ca5ed5832cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_d90a4fe3-5c06-47e3-8f61-81d6385eff55" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_d90a4fe3-5c06-47e3-8f61-81d6385eff55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_480f86ae-db1f-44c9-b179-1ecd463666b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_480f86ae-db1f-44c9-b179-1ecd463666b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_f305021e-43af-4f90-8f13-b4a849b57aaf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_f305021e-43af-4f90-8f13-b4a849b57aaf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_40c4bece-df15-4c15-b39b-3e75222b6b0b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_40c4bece-df15-4c15-b39b-3e75222b6b0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_cb41e886-3ba1-4ef0-9325-dc128096d37d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_665f2bcc-58af-4c89-b97d-938b63ae524e" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_cb41e886-3ba1-4ef0-9325-dc128096d37d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_f28a0993-0b86-4139-a8ac-562572e23b40" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect"/>

<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_f28a0993-0b86-4139-a8ac-562572e23b40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_8c343a08-e568-4765-9437-4c9fed66aa21" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>

<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_8c343a08-e568-4765-9437-4c9fed66aa21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_158aafa1-8990-4f46-ba5a-811bfab4c0fc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>

<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_158aafa1-8990-4f46-ba5a-811bfab4c0fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_ff448292-c337-4052-8c06-7915c8e57de1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract"/>

<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_ff448292-c337-4052-8c06-7915c8e57de1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DueFromBanks_308e4490-f2d9-4247-b0b8-fd92b08a707a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DueFromBanks"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_ff448292-c337-4052-8c06-7915c8e57de1" xlink:to="loc_us-gaap_DueFromBanks_308e4490-f2d9-4247-b0b8-fd92b08a707a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_34f65e8e-6b45-4365-8521-332753bd4567" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_ff448292-c337-4052-8c06-7915c8e57de1" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_34f65e8e-6b45-4365-8521-332753bd4567" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_efd62133-83c9-4423-9d4b-d3f624a5ffb9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsAbstract_ff448292-c337-4052-8c06-7915c8e57de1" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_efd62133-83c9-4423-9d4b-d3f624a5ffb9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_8c3ffae9-e244-4b03-ae5f-05506ff303a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>

<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_8c3ffae9-e244-4b03-ae5f-05506ff303a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPaid_a69b764e-8c09-4f42-8d83-bef1bab5080d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestPaid"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_8c3ffae9-e244-4b03-ae5f-05506ff303a9" xlink:to="loc_us-gaap_InterestPaid_a69b764e-8c09-4f42-8d83-bef1bab5080d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_350ab3e9-de19-46e3-a6c3-141560abb58a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract"/>

<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CondensedCashFlowStatementsCaptionsLineItems_05971d8b-8568-4e70-94f9-658c5f6feef6" xlink:to="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_350ab3e9-de19-46e3-a6c3-141560abb58a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransferToOtherRealEstate_63b94f86-c9f9-4189-b562-7a4d23a3536e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransferToOtherRealEstate"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_350ab3e9-de19-46e3-a6c3-141560abb58a" xlink:to="loc_us-gaap_TransferToOtherRealEstate_63b94f86-c9f9-4189-b562-7a4d23a3536e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_RightofUseAssetAndLiabilityObtainedInExchangeForOperatingLeaseLiability_2d764a0c-cff6-4c03-a03a-b7efaa7f0ee7" xlink:href="ntb-20201231.xsd#ntb_RightofUseAssetAndLiabilityObtainedInExchangeForOperatingLeaseLiability"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_350ab3e9-de19-46e3-a6c3-141560abb58a" xlink:to="loc_ntb_RightofUseAssetAndLiabilityObtainedInExchangeForOperatingLeaseLiability_2d764a0c-cff6-4c03-a03a-b7efaa7f0ee7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_ntb_LoansReduction_99bb9ffc-b2f8-43eb-8795-e50b86accd69" xlink:href="ntb-20201231.xsd#ntb_LoansReduction"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNoncashInvestingAndFinancingItemsAbstract_350ab3e9-de19-46e3-a6c3-141560abb58a" xlink:to="loc_ntb_LoansReduction_99bb9ffc-b2f8-43eb-8795-e50b86accd69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/Subsequentevents" xlink:type="simple" xlink:href="ntb-20201231.xsd#Subsequentevents"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/Subsequentevents" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_b3f6d218-903d-4316-953f-ff199f89205b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_83716e59-909d-4297-867b-b2b74ccfc6b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventsTextBlock"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_b3f6d218-903d-4316-953f-ff199f89205b" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_83716e59-909d-4297-867b-b2b74ccfc6b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

<link:roleRef roleURI="http://www.butterfieldgroup.com/role/SubsequenteventsDetails" xlink:type="simple" xlink:href="ntb-20201231.xsd#SubsequenteventsDetails"/>

<link:presentationLink xlink:role="http://www.butterfieldgroup.com/role/SubsequenteventsDetails" xlink:type="extended">

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_101510bf-3ac3-4079-bc4f-71265dcb82c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_3a82d3f8-18c5-4fb5-87b9-b8bf669019d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTable"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_101510bf-3ac3-4079-bc4f-71265dcb82c9" xlink:to="loc_us-gaap_SubsequentEventTable_3a82d3f8-18c5-4fb5-87b9-b8bf669019d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_576970a2-0bb1-425a-ab27-49f9cfcd5279" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_3a82d3f8-18c5-4fb5-87b9-b8bf669019d1" xlink:to="loc_srt_StatementScenarioAxis_576970a2-0bb1-425a-ab27-49f9cfcd5279" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_b7220b1a-45f7-446c-be3b-a3aadfac29ec" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementScenarioAxis_576970a2-0bb1-425a-ab27-49f9cfcd5279" xlink:to="loc_srt_ScenarioUnspecifiedDomain_b7220b1a-45f7-446c-be3b-a3aadfac29ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_745c7411-adb0-4bc9-aea0-5b66409f5ecb" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioForecastMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScenarioUnspecifiedDomain_b7220b1a-45f7-446c-be3b-a3aadfac29ec" xlink:to="loc_srt_ScenarioForecastMember_745c7411-adb0-4bc9-aea0-5b66409f5ecb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_1098c566-8700-4345-bf32-8c68aab5e8c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_3a82d3f8-18c5-4fb5-87b9-b8bf669019d1" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_1098c566-8700-4345-bf32-8c68aab5e8c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_26cfd3a3-5177-45b7-b1dd-95d9857a8610" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_1098c566-8700-4345-bf32-8c68aab5e8c9" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_26cfd3a3-5177-45b7-b1dd-95d9857a8610" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_465a958c-a305-4291-aafa-dd85fe20142d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventMember"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_26cfd3a3-5177-45b7-b1dd-95d9857a8610" xlink:to="loc_us-gaap_SubsequentEventMember_465a958c-a305-4291-aafa-dd85fe20142d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_7c6f1533-d12c-42c8-972c-1704bc4fd16e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventLineItems"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_3a82d3f8-18c5-4fb5-87b9-b8bf669019d1" xlink:to="loc_us-gaap_SubsequentEventLineItems_7c6f1533-d12c-42c8-972c-1704bc4fd16e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareDeclared_7c10a175-e94c-46ae-b593-7797431bc658" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockDividendsPerShareDeclared"/>

<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_7c6f1533-d12c-42c8-972c-1704bc4fd16e" xlink:to="loc_us-gaap_CommonStockDividendsPerShareDeclared_7c10a175-e94c-46ae-b593-7797431bc658" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareCashPaid_ce504b4b-1581-41aa-80a7-c7a5dd606a32" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockDividendsPerShareCashPaid"/>

<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_7c6f1533-d12c-42c8-972c-1704bc4fd16e" xlink:to="loc_us-gaap_CommonStockDividendsPerShareCashPaid_ce504b4b-1581-41aa-80a7-c7a5dd606a32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramNumberOfSharesAuthorizedToBeRepurchased_65a1de5e-40db-42f1-a13f-500a48ad410f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchaseProgramNumberOfSharesAuthorizedToBeRepurchased"/>

<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_7c6f1533-d12c-42c8-972c-1704bc4fd16e" xlink:to="loc_us-gaap_StockRepurchaseProgramNumberOfSharesAuthorizedToBeRepurchased_65a1de5e-40db-42f1-a13f-500a48ad410f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>

</link:presentationLink>

</link:linkbase>

8 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 6/11/20  Bank of NT Butterfield & Son Ltd  6-K         6/11/20    4:175K                                   Broadridge Fin’l So… Inc
 5/06/20  Bank of NT Butterfield & Son Ltd  S-8         5/06/20    4:5.9M
 4/25/19  Bank of NT Butterfield & Son Ltd  6-K         4/24/19    4:15M
 2/26/19  Bank of NT Butterfield & Son Ltd  20-F       12/31/18  157:37M
 5/24/18  Bank of NT Butterfield & Son Ltd  6-K         5/24/18    6:905K                                   Broadridge Fin’l So… Inc
 9/21/16  Bank of NT Butterfield & Son Ltd  S-8         9/21/16    4:188K                                   Toppan Merrill/FA
 8/30/16  Bank of NT Butterfield & Son Ltd  F-1/A                  5:16M                                    Toppan Merrill-FA
 8/04/16  Bank of NT Butterfield & Son Ltd  F-1                   10:16M                                    Toppan Merrill-FA

↑Top

Filing Submission 0001653242-21-000008 – Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)

Bank of N.T. Butterfield & Son Ltd. – ‘20-F’ for 12/31/20 – ‘EX-101.PRE’

On: Tuesday, 2/23/21, at 4:32pm ET · For: 12/31/20 · Accession #: 1653242-21-8 · File #: 1-37877

Annual or Annual-Transition Report by a Foreign Non-Canadian Issuer — Form 20-F — SEA’34Filing Table of Contents

‘EX-101.PRE’ — XBRL Presentations — ntb-20201231_pre

This Exhibit is an XBRL XML File.

8 Previous Filings that this Filing References

Annual or Annual-Transition Report by a Foreign Non-Canadian Issuer — Form 20-F — SEA’34
Filing Table of Contents