| | | | | | | | | | | | | | | | | | | | | |
<?xml version="1.0" standalone="no" encoding="windows-1252"?> |
<!-- Field: Doc-Info; Name: Generator; Value: GoXBRL; Version: 5.0a --> |
<!-- Field: Doc-Info; Name: VendorURI; Value: http://www.novaworks.co --> |
<!-- Field: Doc-Info; Name: Source; Value: NYMX20F.xfr; Date: 2019%2D08%2D14T19:15:39Z --> |
<!-- Field: Doc-Info; Name: Status; Value: 0x80530003 --> |
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xbrli="http://www.xbrl.org/2003/instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"> |
| <link:roleRef roleURI="http://nymox.com/role/DocumentAndEntityInformation" xlink:href="nymx-20190630.xsd#DocumentAndEntityInformation" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/StatementsOfOperations" xlink:href="nymx-20190630.xsd#StatementsOfOperations" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/StatementsOfFinancialPosition" xlink:href="nymx-20190630.xsd#StatementsOfFinancialPosition" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/StatementsOfFinancialPositionParenthetical" xlink:href="nymx-20190630.xsd#StatementsOfFinancialPositionParenthetical" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/StatementsOfCashFlows" xlink:href="nymx-20190630.xsd#StatementsOfCashFlows" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/StatementsOfChangesInEquity" xlink:href="nymx-20190630.xsd#StatementsOfChangesInEquity" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/BasisOfPreparation" xlink:href="nymx-20190630.xsd#BasisOfPreparation" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/LiquidityGoingConcernAndManagementsResponse" xlink:href="nymx-20190630.xsd#LiquidityGoingConcernAndManagementsResponse" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/ShareCapital" xlink:href="nymx-20190630.xsd#ShareCapital" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/EarningsPerShare" xlink:href="nymx-20190630.xsd#EarningsPerShare" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/OperatingLeaseAndOtherCommitment" xlink:href="nymx-20190630.xsd#OperatingLeaseAndOtherCommitment" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/RelatedPartyTransactions" xlink:href="nymx-20190630.xsd#RelatedPartyTransactions" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/SubsequentEvents" xlink:href="nymx-20190630.xsd#SubsequentEvents" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/ShareCapitalTables" xlink:href="nymx-20190630.xsd#ShareCapitalTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/EarningsPerShareTables" xlink:href="nymx-20190630.xsd#EarningsPerShareTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/OperatingLeaseAndOtherCommitmentTables" xlink:href="nymx-20190630.xsd#OperatingLeaseAndOtherCommitmentTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/RelatedPartyTransactionsTables" xlink:href="nymx-20190630.xsd#RelatedPartyTransactionsTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/ShareCapitalDetails" xlink:href="nymx-20190630.xsd#ShareCapitalDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/ShareCapitalDetails1" xlink:href="nymx-20190630.xsd#ShareCapitalDetails1" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/ShareCapitalDetails2" xlink:href="nymx-20190630.xsd#ShareCapitalDetails2" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/ShareCapitalDetailsNarrative" xlink:href="nymx-20190630.xsd#ShareCapitalDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/EarningsPerShareDetails" xlink:href="nymx-20190630.xsd#EarningsPerShareDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/OperationLeaseAndOtherCommitmentDetails" xlink:href="nymx-20190630.xsd#OperationLeaseAndOtherCommitmentDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/OperationLeaseAndOtherCommitmentDetails1" xlink:href="nymx-20190630.xsd#OperationLeaseAndOtherCommitmentDetails1" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/OperationLeaseAndOtherCommitmentDetailsNarrative" xlink:href="nymx-20190630.xsd#OperationLeaseAndOtherCommitmentDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/RelatedPartyTransactionsDetails" xlink:href="nymx-20190630.xsd#RelatedPartyTransactionsDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://nymox.com/role/RelatedPartyTransactionsDetailsNarrative" xlink:href="nymx-20190630.xsd#RelatedPartyTransactionsDetailsNarrative" xlink:type="simple"/> |
| <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension"/> |
| <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain"/> |
| <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member"/> |
| <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" arcroleURI="http://xbrl.org/int/dim/arcrole/all"/> |
| <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#notAll" arcroleURI="http://xbrl.org/int/dim/arcrole/notAll"/> |
| <link:arcroleRef xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/DocumentAndEntityInformation" xlink:title="00000001 - Document - Document and Entity Information"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/StatementsOfOperations" xlink:title="00000002 - Statement - Consolidated Statements of Operations (Unaudited)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/StatementsOfFinancialPosition" xlink:title="00000003 - Statement - Consolidated Statements of Financial Position"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/StatementsOfFinancialPositionParenthetical" xlink:title="00000004 - Statement - Consolidated Statements of Financial Position (Parenthetical)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/StatementsOfCashFlows" xlink:title="00000005 - Statement - Consolidated Statements of Cash Flows (Unaudited)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/StatementsOfChangesInEquity" xlink:title="00000006 - Statement - Consolidated Statements of Changes in Equity (Unaudited)"> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_IfrsStatementLineItems" xlink:label="loc_NYMXIfrsStatementLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_IfrsStatementTable" xlink:label="loc_NYMXIfrsStatementTable"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXIfrsStatementTable" xlink:type="arc" order="10" xbrldt:closed="true"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_ComponentsOfEquityAxis" xlink:label="loc_ifrs-fullComponentsOfEquityAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_NYMXIfrsStatementTable" xlink:to="loc_ifrs-fullComponentsOfEquityAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EquityMember" xlink:label="loc_ifrs-fullEquityMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullComponentsOfEquityAxis" xlink:to="loc_ifrs-fullEquityMember" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EquityMember" xlink:label="loc_ifrs-fullEquityMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullComponentsOfEquityAxis" xlink:to="loc_ifrs-fullEquityMember_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_IssuedCapitalMember" xlink:label="loc_ifrs-fullIssuedCapitalMember_0"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEquityMember" xlink:to="loc_ifrs-fullIssuedCapitalMember_0" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_SharePremiumMember" xlink:label="loc_ifrs-fullSharePremiumMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEquityMember" xlink:to="loc_ifrs-fullSharePremiumMember_10" xlink:type="arc" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_OtherReservesMember" xlink:label="loc_ifrs-fullOtherReservesMember_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEquityMember" xlink:to="loc_ifrs-fullOtherReservesMember_20" xlink:type="arc" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_RetainedEarningsMember" xlink:label="loc_ifrs-fullRetainedEarningsMember_30"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEquityMember" xlink:to="loc_ifrs-fullRetainedEarningsMember_30" xlink:type="arc" order="31"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_NumberOfSharesIssued" xlink:label="loc_ifrs-fullNumberOfSharesIssued_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_ifrs-fullNumberOfSharesIssued_60" xlink:type="arc" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_Equity" xlink:label="loc_ifrs-fullEquity_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_ifrs-fullEquity_60" xlink:type="arc" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_LeaseAdpotionPriorYearCumulativeEffect" xlink:label="loc_NYMXLeaseAdpotionPriorYearCumulativeEffect_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXLeaseAdpotionPriorYearCumulativeEffect_60" xlink:type="arc" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_SharesIssuanceForCashAndSubscriptionsShares" xlink:label="loc_NYMXSharesIssuanceForCashAndSubscriptionsShares_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXSharesIssuanceForCashAndSubscriptionsShares_60" xlink:type="arc" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_SharesIssuanceForCashAndSubscriptionsAmount" xlink:label="loc_NYMXSharesIssuanceForCashAndSubscriptionsAmount_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXSharesIssuanceForCashAndSubscriptionsAmount_60" xlink:type="arc" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WarrantIssued" xlink:label="loc_NYMXWarrantIssued_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXWarrantIssued_60" xlink:type="arc" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_StockbasedCompensationShares" xlink:label="loc_NYMXStockbasedCompensationShares_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXStockbasedCompensationShares_60" xlink:type="arc" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_StockbasedCompensationAmount" xlink:label="loc_NYMXStockbasedCompensationAmount_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXStockbasedCompensationAmount_60" xlink:type="arc" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_ProfitLoss" xlink:label="loc_ifrs-fullProfitLoss_60"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_ifrs-fullProfitLoss_60" xlink:type="arc" order="11"/> |
| | </link:definitionLink> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/BasisOfPreparation" xlink:title="00000007 - Disclosure - Basis of preparation"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/LiquidityGoingConcernAndManagementsResponse" xlink:title="00000008 - Disclosure - Liquidity, Going Concern and Management’s Response"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/ShareCapital" xlink:title="00000009 - Disclosure - Share capital"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/EarningsPerShare" xlink:title="00000010 - Disclosure - Earnings per share"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/OperatingLeaseAndOtherCommitment" xlink:title="00000011 - Disclosure - Operating lease and other commitment"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/RelatedPartyTransactions" xlink:title="00000012 - Disclosure - Related Party Transactions"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/SubsequentEvents" xlink:title="00000013 - Disclosure - Subsequent events"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/ShareCapitalTables" xlink:title="00000014 - Disclosure - Share capital (Tables)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/EarningsPerShareTables" xlink:title="00000015 - Disclosure - Earnings per share (Tables)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/OperatingLeaseAndOtherCommitmentTables" xlink:title="00000016 - Disclosure - Operating lease and other commitment (Tables)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/RelatedPartyTransactionsTables" xlink:title="00000017 - Disclosure - Related Party Transactions (Tables)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/ShareCapitalDetails" xlink:title="00000018 - Disclosure - Share capital (Details)"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfFinancialAssetsLineItems" xlink:label="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfFinancialAssetsTable" xlink:label="loc_ifrs-fullDisclosureOfFinancialAssetsTable"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_ifrs-fullDisclosureOfFinancialAssetsTable" xlink:type="arc" order="10" xbrldt:closed="true"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_ClassesOfFinancialAssetsAxis" xlink:label="loc_ifrs-fullClassesOfFinancialAssetsAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsTable" xlink:to="loc_ifrs-fullClassesOfFinancialAssetsAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_FinancialAssetsMember" xlink:label="loc_ifrs-fullFinancialAssetsMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullClassesOfFinancialAssetsAxis" xlink:to="loc_ifrs-fullFinancialAssetsMember" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_FinancialAssetsMember" xlink:label="loc_ifrs-fullFinancialAssetsMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullClassesOfFinancialAssetsAxis" xlink:to="loc_ifrs-fullFinancialAssetsMember_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_StockOptionsMember" xlink:label="loc_NYMXStockOptionsMember_0"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullFinancialAssetsMember" xlink:to="loc_NYMXStockOptionsMember_0" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_ClasseOfOptionsOrRightsOutstanding" xlink:label="loc_NYMXClasseOfOptionsOrRightsOutstanding_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXClasseOfOptionsOrRightsOutstanding_20" xlink:type="arc" order="0"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_NumberOfShareOptionsExpiredUnderlyingShares" xlink:label="loc_NYMXNumberOfShareOptionsExpiredUnderlyingShares_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXNumberOfShareOptionsExpiredUnderlyingShares_20" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_NumberOfShareOptionsGrantedUnderlyingShares" xlink:label="loc_NYMXNumberOfShareOptionsGrantedUnderlyingShares_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXNumberOfShareOptionsGrantedUnderlyingShares_20" xlink:type="arc" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_NumberOfShareOptionsOutstandingExercisableUnderlyingShares" xlink:label="loc_NYMXNumberOfShareOptionsOutstandingExercisableUnderlyingShares_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXNumberOfShareOptionsOutstandingExercisableUnderlyingShares_20" xlink:type="arc" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageExercisePricePerShareBeginning" xlink:label="loc_NYMXWeightedAverageExercisePricePerShareBeginning_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageExercisePricePerShareBeginning_20" xlink:type="arc" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageExercisePricePerShareExpired" xlink:label="loc_NYMXWeightedAverageExercisePricePerShareExpired_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageExercisePricePerShareExpired_20" xlink:type="arc" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageExercisePricePerShareGranted" xlink:label="loc_NYMXWeightedAverageExercisePricePerShareGranted_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageExercisePricePerShareGranted_20" xlink:type="arc" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageExercisePricePerShareExercisable" xlink:label="loc_NYMXWeightedAverageExercisePricePerShareExercisable_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageExercisePricePerShareExercisable_20" xlink:type="arc" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageRemainingContractualLifeInYearsBeginning" xlink:label="loc_NYMXWeightedAverageRemainingContractualLifeInYearsBeginning_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageRemainingContractualLifeInYearsBeginning_20" xlink:type="arc" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageRemainingContractualLifeInCancelled" xlink:label="loc_NYMXWeightedAverageRemainingContractualLifeInCancelled_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageRemainingContractualLifeInCancelled_20" xlink:type="arc" order="13"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageRemainingContractualLifeInGranted" xlink:label="loc_NYMXWeightedAverageRemainingContractualLifeInGranted_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageRemainingContractualLifeInGranted_20" xlink:type="arc" order="14"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageRemainingContractualLifeOptionsOutstanding" xlink:label="loc_NYMXWeightedAverageRemainingContractualLifeOptionsOutstanding_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageRemainingContractualLifeOptionsOutstanding_20" xlink:type="arc" order="15"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WeightedAverageRemainingContractualLifeInExercisable" xlink:label="loc_NYMXWeightedAverageRemainingContractualLifeInExercisable_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFinancialAssetsLineItems" xlink:to="loc_NYMXWeightedAverageRemainingContractualLifeInExercisable_20" xlink:type="arc" order="16"/> |
| | </link:definitionLink> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/ShareCapitalDetails1" xlink:title="00000019 - Disclosure - Share capital (Details 1)"> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_IfrsStatementLineItems" xlink:label="loc_NYMXIfrsStatementLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_IfrsStatementTable" xlink:label="loc_NYMXIfrsStatementTable"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXIfrsStatementTable" xlink:type="arc" order="10" xbrldt:closed="true"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_CreationDateAxis" xlink:label="loc_ifrs-fullCreationDateAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_NYMXIfrsStatementTable" xlink:to="loc_ifrs-fullCreationDateAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_CreationDateDomain" xlink:label="loc_NYMXCreationDateDomain"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullCreationDateAxis" xlink:to="loc_NYMXCreationDateDomain" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_CreationDateDomain" xlink:label="loc_NYMXCreationDateDomain_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullCreationDateAxis" xlink:to="loc_NYMXCreationDateDomain_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_GrantedInTwoZeroOneFiveMember" xlink:label="loc_NYMXGrantedInTwoZeroOneFiveMember_0"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXCreationDateDomain" xlink:to="loc_NYMXGrantedInTwoZeroOneFiveMember_0" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_GrantedInTwoZeroOneEightMember" xlink:label="loc_NYMXGrantedInTwoZeroOneEightMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXCreationDateDomain" xlink:to="loc_NYMXGrantedInTwoZeroOneEightMember_10" xlink:type="arc" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_GrantedInTwoZeroOneNinteenMember" xlink:label="loc_NYMXGrantedInTwoZeroOneNinteenMember_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXCreationDateDomain" xlink:to="loc_NYMXGrantedInTwoZeroOneNinteenMember_20" xlink:type="arc" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_EmployeeExpenseAbstract" xlink:label="loc_NYMXEmployeeExpenseAbstract_170"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXIfrsStatementLineItems" xlink:to="loc_NYMXEmployeeExpenseAbstract_170" xlink:type="arc" order="0"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_TotalStockbasedCompensationExpenseRecognized" xlink:label="loc_NYMXTotalStockbasedCompensationExpenseRecognized_170"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_NYMXEmployeeExpenseAbstract_170" xlink:to="loc_NYMXTotalStockbasedCompensationExpenseRecognized_170" xlink:type="arc" order="1"/> |
| | </link:definitionLink> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/ShareCapitalDetails2" xlink:title="00000020 - Disclosure - Share capital (Details 2)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/ShareCapitalDetailsNarrative" xlink:title="00000021 - Disclosure - Share capital (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:type="arc" order="10" xbrldt:closed="true"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_CategoriesOfRelatedPartiesAxis" xlink:label="loc_ifrs-fullCategoriesOfRelatedPartiesAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:to="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EntitysTotalForRelatedPartiesMember" xlink:label="loc_ifrs-fullEntitysTotalForRelatedPartiesMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:to="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EntitysTotalForRelatedPartiesMember" xlink:label="loc_ifrs-fullEntitysTotalForRelatedPartiesMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:to="loc_ifrs-fullEntitysTotalForRelatedPartiesMember_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_RelatedPartiesMember" xlink:label="loc_ifrs-fullRelatedPartiesMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:to="loc_ifrs-fullRelatedPartiesMember_10" xlink:type="arc" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_StockOptionPlanDescription" xlink:label="loc_NYMXStockOptionPlanDescription_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXStockOptionPlanDescription_50" xlink:type="arc" order="0"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_StockOptionAviableToBeGranted" xlink:label="loc_NYMXStockOptionAviableToBeGranted_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXStockOptionAviableToBeGranted_50" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_ProceedsFromIssueOfOrdinaryShares" xlink:label="loc_ifrs-fullProceedsFromIssueOfOrdinaryShares_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullProceedsFromIssueOfOrdinaryShares_50" xlink:type="arc" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_CommonStockShareIssued" xlink:label="loc_NYMXCommonStockShareIssued_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXCommonStockShareIssued_50" xlink:type="arc" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_PricePerShare" xlink:label="loc_NYMXPricePerShare_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXPricePerShare_50" xlink:type="arc" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_NumberOfWarrantsIssued" xlink:label="loc_NYMXNumberOfWarrantsIssued_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXNumberOfWarrantsIssued_50" xlink:type="arc" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_ValueOfWarrantIssued" xlink:label="loc_NYMXValueOfWarrantIssued_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXValueOfWarrantIssued_50" xlink:type="arc" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_TermOfWarrants" xlink:label="loc_NYMXTermOfWarrants_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXTermOfWarrants_50" xlink:type="arc" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_WarrantsExercisePrice" xlink:label="loc_NYMXWarrantsExercisePrice_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXWarrantsExercisePrice_50" xlink:type="arc" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_CommonStockShareIssuableUponExerciseOfEachWarrant" xlink:label="loc_NYMXCommonStockShareIssuableUponExerciseOfEachWarrant_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXCommonStockShareIssuableUponExerciseOfEachWarrant_50" xlink:type="arc" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesIssuedForServices" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesIssuedForServices_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesIssuedForServices_50" xlink:type="arc" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueIssuedForServices" xlink:label="loc_us-gaapStockIssuedDuringPeriodValueIssuedForServices_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodValueIssuedForServices_50" xlink:type="arc" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_StockOptionGranted" xlink:label="loc_NYMXStockOptionGranted_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXStockOptionGranted_50" xlink:type="arc" order="13"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_NumberOfDirectors" xlink:label="loc_NYMXNumberOfDirectors_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXNumberOfDirectors_50" xlink:type="arc" order="14"/> |
| | </link:definitionLink> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/EarningsPerShareDetails" xlink:title="00000022 - Disclosure - Earnings per share (Details)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/OperationLeaseAndOtherCommitmentDetails" xlink:title="00000023 - Disclosure - Operation lease and other commitment (Details)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/OperationLeaseAndOtherCommitmentDetails1" xlink:title="00000024 - Disclosure - Operation lease and other commitment (Details 1)"/> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/OperationLeaseAndOtherCommitmentDetailsNarrative" xlink:title="00000025 - Disclosure - Operation lease and other commitment (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:label="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesTable" xlink:label="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesTable"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesTable" xlink:type="arc" order="10" xbrldt:closed="true"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_MaturityAxis" xlink:label="loc_ifrs-fullMaturityAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesTable" xlink:to="loc_ifrs-fullMaturityAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_AggregatedTimeBandsMember" xlink:label="loc_ifrs-fullAggregatedTimeBandsMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullMaturityAxis" xlink:to="loc_ifrs-fullAggregatedTimeBandsMember" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_AggregatedTimeBandsMember" xlink:label="loc_ifrs-fullAggregatedTimeBandsMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullMaturityAxis" xlink:to="loc_ifrs-fullAggregatedTimeBandsMember_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_JanuaryOneTwoThousandNineteenMember" xlink:label="loc_NYMXJanuaryOneTwoThousandNineteenMember_0"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullAggregatedTimeBandsMember" xlink:to="loc_NYMXJanuaryOneTwoThousandNineteenMember_0" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_ImmaterialCumulativeAdjustmentToAccumulatedDeficit" xlink:label="loc_NYMXImmaterialCumulativeAdjustmentToAccumulatedDeficit_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_NYMXImmaterialCumulativeAdjustmentToAccumulatedDeficit_40" xlink:type="arc" order="0"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_DescriptionForDiscountRateChanges" xlink:label="loc_NYMXDescriptionForDiscountRateChanges_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_NYMXDescriptionForDiscountRateChanges_40" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_OperatingLeaseAssets" xlink:label="loc_NYMXOperatingLeaseAssets_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_NYMXOperatingLeaseAssets_40" xlink:type="arc" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_OperatingLeaseLiabilities" xlink:label="loc_NYMXOperatingLeaseLiabilities_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_NYMXOperatingLeaseLiabilities_40" xlink:type="arc" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_AverageRemainingTermOfLease" xlink:label="loc_NYMXAverageRemainingTermOfLease_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_NYMXAverageRemainingTermOfLease_40" xlink:type="arc" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_TotalFutureCommitmentPaymentDue" xlink:label="loc_NYMXTotalFutureCommitmentPaymentDue_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_NYMXTotalFutureCommitmentPaymentDue_40" xlink:type="arc" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_LeaseLiabilities" xlink:label="loc_ifrs-fullLeaseLiabilities_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfMaturityAnalysisForNonderivativeFinancialLiabilitiesLineItems" xlink:to="loc_ifrs-fullLeaseLiabilities_40" xlink:type="arc" order="6"/> |
| | </link:definitionLink> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/RelatedPartyTransactionsDetails" xlink:title="00000026 - Disclosure - Related Party Transactions (Details)"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:type="arc" order="10" xbrldt:closed="true"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_CategoriesOfRelatedPartiesAxis" xlink:label="loc_ifrs-fullCategoriesOfRelatedPartiesAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:to="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EntitysTotalForRelatedPartiesMember" xlink:label="loc_ifrs-fullEntitysTotalForRelatedPartiesMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:to="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EntitysTotalForRelatedPartiesMember" xlink:label="loc_ifrs-fullEntitysTotalForRelatedPartiesMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:to="loc_ifrs-fullEntitysTotalForRelatedPartiesMember_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_OfficersAndDirectorsMember" xlink:label="loc_NYMXOfficersAndDirectorsMember_0"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:to="loc_NYMXOfficersAndDirectorsMember_0" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_WagesAndSalaries" xlink:label="loc_ifrs-fullWagesAndSalaries_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullWagesAndSalaries_50" xlink:type="arc" order="0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits" xlink:label="loc_ifrs-fullKeyManagementPersonnelCompensationShorttermEmployeeBenefits_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullKeyManagementPersonnelCompensationShorttermEmployeeBenefits_50" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_KeyManagementPersonnelCompensationSharebasedPayment" xlink:label="loc_ifrs-fullKeyManagementPersonnelCompensationSharebasedPayment_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullKeyManagementPersonnelCompensationSharebasedPayment_50" xlink:type="arc" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_KeyManagementPersonnelCompensation" xlink:label="loc_ifrs-fullKeyManagementPersonnelCompensation_50"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullKeyManagementPersonnelCompensation_50" xlink:type="arc" order="3"/> |
| | </link:definitionLink> |
| <link:definitionLink xlink:type="extended" xlink:role="http://nymox.com/role/RelatedPartyTransactionsDetailsNarrative" xlink:title="00000027 - Disclosure - Related Party Transactions (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:type="arc" order="10" xbrldt:closed="true"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_CategoriesOfRelatedPartiesAxis" xlink:label="loc_ifrs-fullCategoriesOfRelatedPartiesAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:to="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EntitysTotalForRelatedPartiesMember" xlink:label="loc_ifrs-fullEntitysTotalForRelatedPartiesMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:to="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_EntitysTotalForRelatedPartiesMember" xlink:label="loc_ifrs-fullEntitysTotalForRelatedPartiesMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullCategoriesOfRelatedPartiesAxis" xlink:to="loc_ifrs-fullEntitysTotalForRelatedPartiesMember_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_CorporateLegalCounselMember" xlink:label="loc_NYMXCorporateLegalCounselMember_0"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:to="loc_NYMXCorporateLegalCounselMember_0" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_ChiefFinancialOfficersMember" xlink:label="loc_NYMXChiefFinancialOfficersMember_20"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:to="loc_NYMXChiefFinancialOfficersMember_20" xlink:type="arc" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_RelatedPartiesMember" xlink:label="loc_ifrs-fullRelatedPartiesMember_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullEntitysTotalForRelatedPartiesMember" xlink:to="loc_ifrs-fullRelatedPartiesMember_40" xlink:type="arc" order="41"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20190630.xsd#NYMX_AmountsPaidUnderContractForServices" xlink:label="loc_NYMXAmountsPaidUnderContractForServices_70"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXAmountsPaidUnderContractForServices_70" xlink:type="arc" order="0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesIssuedForServices" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesIssuedForServices_70"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesIssuedForServices_70" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueIssuedForServices" xlink:label="loc_us-gaapStockIssuedDuringPeriodValueIssuedForServices_70"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_us-gaapStockIssuedDuringPeriodValueIssuedForServices_70" xlink:type="arc" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SaleOfStockPricePerShare" xlink:label="loc_us-gaapSaleOfStockPricePerShare_70"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_us-gaapSaleOfStockPricePerShare_70" xlink:type="arc" order="3"/> |
| | </link:definitionLink> |
| </link:linkbase> |