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Guided Therapeutics Inc. – ‘10-Q’ for 9/30/23 – ‘EX-101.LAB’

On:  Monday, 11/13/23, at 3:28pm ET   ·   For:  9/30/23   ·   Accession #:  1477932-23-8286   ·   File #:  0-22179

Previous ‘10-Q’:  ‘10-Q’ on 8/10/23 for 6/30/23   ·   Latest ‘10-Q’:  This Filing   ·   8 References:   

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  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

11/13/23  Guided Therapeutics Inc.          10-Q        9/30/23   71:6.9M                                   Discount Edgar/FA

Quarterly Report   —   Form 10-Q

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-Q        Quarterly Report                                    HTML   1.69M 
 2: EX-31       Certification -- §302 - SOA'02                      HTML     23K 
 3: EX-32       Certification -- §906 - SOA'02                      HTML     20K 
 9: R1          Cover                                               HTML     67K 
10: R2          Condensed Consolidated Balance Sheets               HTML    151K 
11: R3          Condensed Consolidated Balance Sheets               HTML     70K 
                (Parenthetical)                                                  
12: R4          Condensed Consolidated Statements of Operations     HTML    115K 
                (Unaudited)                                                      
13: R5          Condensed Consolidated Statements of Stockholders'  HTML    133K 
                Deficit (Unaudited)                                              
14: R6          Condensed Consolidated Statements of Cash Flows     HTML    110K 
                (Unaudited)                                                      
15: R7          Organization Background and Basis of Presentation   HTML     29K 
16: R8          Significant Accounting Policies                     HTML     78K 
17: R9          Fair Value of Financial Instruments                 HTML     38K 
18: R10         Stockholders Deficit                                HTML     71K 
19: R11         Stock Options                                       HTML     48K 
20: R12         Litigation and Claims                               HTML     21K 
21: R13         Commitments and Contingencies                       HTML     66K 
22: R14         Notes Payable                                       HTML     31K 
23: R15         Auctus Convertible Debt                             HTML     33K 
24: R16         Long Term Debt                                      HTML     52K 
25: R17         Income (Loss) Per Share of Common Stock             HTML     38K 
26: R18         Subsequent Events                                   HTML     21K 
27: R19         Significant Accounting Policies (Policies)          HTML    119K 
28: R20         Significant Accounting Policies (Tables)            HTML     56K 
29: R21         Fair Value of Financial Instruments (Tables)        HTML     37K 
30: R22         Stockholders Deficit (Tables)                       HTML     49K 
31: R23         Stock Options (Tables)                              HTML     46K 
32: R24         Commitments and Contingencies (Tables)              HTML     56K 
33: R25         Notes Payable (Tables)                              HTML     26K 
34: R26         Convertible Debt (Tables)                           HTML     25K 
35: R27         Long Term Debt (Tables)                             HTML     46K 
36: R28         Income (Loss) Per Share of Common Stock (Tables)    HTML     35K 
37: R29         Organization Background and Basis of Presentation   HTML     29K 
                (Details Narrative)                                              
38: R30         Significant Accounting Policies (Details)           HTML     29K 
39: R31         Significant Accounting Policies (Details 1)         HTML     32K 
40: R32         Significant Accounting Policies (Details 2)         HTML     35K 
41: R33         Significant Accounting Policies (Details            HTML     44K 
                Narrative)                                                       
42: R34         Fair Value of Financial Instruments (Details)       HTML     34K 
43: R35         Fair Value of Financial Instruments (Details 1)     HTML     31K 
44: R36         Fair Value of Financial Instruments (Details        HTML     20K 
                Narrative)                                                       
45: R37         Stockholders Deficit (Details)                      HTML     43K 
46: R38         Stockholders Deficit (Details 1)                    HTML     41K 
47: R39         Stockholders Deficit (Details 2)                    HTML     28K 
48: R40         Stockholders Deficit (Details Narrative)            HTML    175K 
49: R41         Stock Options (Details)                             HTML     25K 
50: R42         Stock Options (Details 1)                           HTML     44K 
51: R43         Stock Options (Details 2)                           HTML     24K 
52: R44         Stock Option (Details Narrative)                    HTML     45K 
53: R45         Commitments and Contingencies (Details)             HTML     22K 
54: R46         Commitments and Contingencies (Details 1)           HTML     33K 
55: R47         Commitments and Contingencies (Details 2)           HTML     22K 
56: R48         Commitments and Contingencies (Details 3)           HTML     39K 
57: R49         Commitments and Contingencies (Details Narrative)   HTML     96K 
58: R50         Notes Payable (Details)                             HTML     24K 
59: R51         Notes Payable (Details Narrative)                   HTML     39K 
60: R52         Convertible Debt (Details)                          HTML     26K 
61: R53         Convertible Debt (Details Narrative)                HTML     85K 
62: R54         Long Term Debt (Details)                            HTML     47K 
63: R55         Long Term Debt (Details 1)                          HTML     33K 
64: R56         Long Term Debt (Details Narrative)                  HTML     86K 
65: R57         Income (Loss) Per Share of Common Stock (Details)   HTML     56K 
66: R58         Subsequent Events (Details)                         HTML     21K 
69: XML         IDEA XML File -- Filing Summary                      XML    128K 
67: XML         XBRL Instance -- gthp_10q_htm                        XML   1.78M 
68: EXCEL       IDEA Workbook of Financial Report Info              XLSX    144K 
 6: EX-101.CAL  XBRL Calculations -- gthp-20230930_cal               XML    142K 
 8: EX-101.DEF  XBRL Definitions -- gthp-20230930_def                XML    665K 
 5: EX-101.LAB  XBRL Labels -- gthp-20230930_lab                     XML   1.12M 
 7: EX-101.PRE  XBRL Presentations -- gthp-20230930_pre              XML    916K 
 4: EX-101.SCH  XBRL Schema -- gthp-20230930                         XSD    260K 
70: JSON        XBRL Instance as JSON Data -- MetaLinks              458±   633K 
71: ZIP         XBRL Zipped Folder -- 0001477932-23-008286-xbrl      Zip    263K

‘EX-101.LAB’   —   XBRL Labels — gthp-20230930_lab

This Exhibit is an XBRL File.

                                                                                                                                                                                
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<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentFlag" xlink:label="dei_AmendmentFlag"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AmendmentFlag" xlink:to="dei_AmendmentFlag_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_AmendmentFlag_lbl" xml:lang="en-US"> Amendment Flag </link:label>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CurrentFiscalYearEndDate_lbl" xml:lang="en-US"> Current Fiscal Year End Date </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntitySmallBusiness" xlink:label="dei_EntitySmallBusiness"/>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntitySmallBusiness_lbl" xml:lang="en-US"> Entity Small Business </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityShellCompany" xlink:label="dei_EntityShellCompany"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityShellCompany" xlink:to="dei_EntityShellCompany_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityShellCompany_lbl" xml:lang="en-US"> Entity Shell Company </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityEmergingGrowthCompany" xlink:label="dei_EntityEmergingGrowthCompany"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityEmergingGrowthCompany" xlink:to="dei_EntityEmergingGrowthCompany_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityEmergingGrowthCompany_lbl" xml:lang="en-US"> Entity Emerging Growth Company </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCurrentReportingStatus" xlink:label="dei_EntityCurrentReportingStatus"/>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCurrentReportingStatus_lbl" xml:lang="en-US"> Entity Current Reporting Status </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodEndDate" xlink:label="dei_DocumentPeriodEndDate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentPeriodEndDate" xlink:to="dei_DocumentPeriodEndDate_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentPeriodEndDate_lbl" xml:lang="en-US"> Document Period End Date </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFilerCategory" xlink:label="dei_EntityFilerCategory"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityFilerCategory" xlink:to="dei_EntityFilerCategory_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityFilerCategory_lbl" xml:lang="en-US"> Entity Filer Category </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="dei_DocumentFiscalPeriodFocus"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentFiscalPeriodFocus" xlink:to="dei_DocumentFiscalPeriodFocus_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentFiscalPeriodFocus_lbl" xml:lang="en-US"> Document Fiscal Period Focus </link:label>
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<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentFiscalYearFocus" xlink:to="dei_DocumentFiscalYearFocus_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentFiscalYearFocus_lbl" xml:lang="en-US"> Document Fiscal Year Focus </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="dei_EntityCommonStockSharesOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCommonStockSharesOutstanding" xlink:to="dei_EntityCommonStockSharesOutstanding_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityCommonStockSharesOutstanding_lbl" xml:lang="en-US"> Entity Common Stock Shares Outstanding </link:label>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityFileNumber_lbl" xml:lang="en-US"> Entity File Number </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="dei_EntityIncorporationStateCountryCode"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityIncorporationStateCountryCode" xlink:to="dei_EntityIncorporationStateCountryCode_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityIncorporationStateCountryCode_lbl" xml:lang="en-US"> Entity Incorporation State Country Code </link:label>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityTaxIdentificationNumber_lbl" xml:lang="en-US"> Entity Tax Identification Number </link:label>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressAddressLine2_lbl" xml:lang="en-US"> Entity Address Address Line 2 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCityOrTown" xlink:label="dei_EntityAddressCityOrTown"/>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressCityOrTown_lbl" xml:lang="en-US"> Entity Address City Or Town </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressStateOrProvince" xlink:label="dei_EntityAddressStateOrProvince"/>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressStateOrProvince_lbl" xml:lang="en-US"> Entity Address State Or Province </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressPostalZipCode" xlink:label="dei_EntityAddressPostalZipCode"/>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityAddressPostalZipCode_lbl" xml:lang="en-US"> Entity Address Postal Zip Code </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CityAreaCode" xlink:label="dei_CityAreaCode"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CityAreaCode" xlink:to="dei_CityAreaCode_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_CityAreaCode_lbl" xml:lang="en-US"> City Area Code </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LocalPhoneNumber" xlink:label="dei_LocalPhoneNumber"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_LocalPhoneNumber" xlink:to="dei_LocalPhoneNumber_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_LocalPhoneNumber_lbl" xml:lang="en-US"> Local Phone Number </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentQuarterlyReport" xlink:label="dei_DocumentQuarterlyReport"/>
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<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentQuarterlyReport_lbl" xml:lang="en-US"> Document Quarterly Report </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentTransitionReport" xlink:label="dei_DocumentTransitionReport"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentTransitionReport" xlink:to="dei_DocumentTransitionReport_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_DocumentTransitionReport_lbl" xml:lang="en-US"> Document Transition Report </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityInteractiveDataCurrent" xlink:label="dei_EntityInteractiveDataCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityInteractiveDataCurrent" xlink:to="dei_EntityInteractiveDataCurrent_lbl" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="dei_EntityInteractiveDataCurrent_lbl" xml:lang="en-US"> Entity Interactive Data Current </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="us-gaap_StatementOfFinancialPositionAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementOfFinancialPositionAbstract" xlink:to="us-gaap_StatementOfFinancialPositionAbstract_lbl_6e8273" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementOfFinancialPositionAbstract_lbl_6e8273" xml:lang="en-US"> CONDENSED CONSOLIDATED BALANCE SHEETS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementTable" xlink:label="us-gaap_StatementTable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementTable" xlink:to="us-gaap_StatementTable_lbl_657731" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementTable_lbl_657731" xml:lang="en-US"> Statement [Table] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementLineItems" xlink:label="us-gaap_StatementLineItems"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementLineItems" xlink:to="us-gaap_StatementLineItems_lbl_56788a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementLineItems_lbl_56788a" xml:lang="en-US"> Statement [Line Items] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="us-gaap_StatementClassOfStockAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementClassOfStockAxis" xlink:to="us-gaap_StatementClassOfStockAxis_lbl_40a818" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementClassOfStockAxis_lbl_40a818" xml:lang="en-US"> Class of Stock [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesCPreferredSharesMember" xlink:label="gthp_SeriesCPreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesCPreferredSharesMember" xlink:to="gthp_SeriesCPreferredSharesMember_lbl_af71cf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesCPreferredSharesMember_lbl_af71cf" xml:lang="en-US"> Series C Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesCOnePreferredSharesMember" xlink:label="gthp_SeriesCOnePreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesCOnePreferredSharesMember" xlink:to="gthp_SeriesCOnePreferredSharesMember_lbl_c499f6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesCOnePreferredSharesMember_lbl_c499f6" xml:lang="en-US"> Series C1 Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesCTwoPreferredSharesMember" xlink:label="gthp_SeriesCTwoPreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesCTwoPreferredSharesMember" xlink:to="gthp_SeriesCTwoPreferredSharesMember_lbl_05246a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesCTwoPreferredSharesMember_lbl_05246a" xml:lang="en-US"> Series C2 Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesDConvertiblePreferredSharesMember" xlink:label="gthp_SeriesDConvertiblePreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesDConvertiblePreferredSharesMember" xlink:to="gthp_SeriesDConvertiblePreferredSharesMember_lbl_175626" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesDConvertiblePreferredSharesMember_lbl_175626" xml:lang="en-US"> Series D Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesEConvertiblePreferredSharesMember" xlink:label="gthp_SeriesEConvertiblePreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesEConvertiblePreferredSharesMember" xlink:to="gthp_SeriesEConvertiblePreferredSharesMember_lbl_19e729" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesEConvertiblePreferredSharesMember_lbl_19e729" xml:lang="en-US"> Series E Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesFConvertiblePreferredSharesMember" xlink:label="gthp_SeriesFConvertiblePreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesFConvertiblePreferredSharesMember" xlink:to="gthp_SeriesFConvertiblePreferredSharesMember_lbl_0608d9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesFConvertiblePreferredSharesMember_lbl_0608d9" xml:lang="en-US"> Series F Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesFTwoConvertiblePreferredSharesMember" xlink:label="gthp_SeriesFTwoConvertiblePreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesFTwoConvertiblePreferredSharesMember" xlink:to="gthp_SeriesFTwoConvertiblePreferredSharesMember_lbl_dd0be8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesFTwoConvertiblePreferredSharesMember_lbl_dd0be8" xml:lang="en-US"> Series F-2 Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsAbstract" xlink:label="us-gaap_AssetsAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsAbstract" xlink:to="us-gaap_AssetsAbstract_lbl_7a2d9b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AssetsAbstract_lbl_7a2d9b" xml:lang="en-US"> ASSETS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="us-gaap_AssetsCurrentAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsCurrentAbstract" xlink:to="us-gaap_AssetsCurrentAbstract_lbl_7f7dff" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AssetsCurrentAbstract_lbl_7f7dff" xml:lang="en-US"> Current Assets: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:to="us-gaap_CashAndCashEquivalentsAtCarryingValue_lbl_24565f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_lbl_24565f" xml:lang="en-US"> Cash and cash equivalents </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockValue" xlink:label="us-gaap_PreferredStockValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockValue" xlink:to="us-gaap_PreferredStockValue_lbl_5c75d0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockValue_lbl_5c75d0" xml:lang="en-US"> Preferred stock, value </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="us-gaap_AccountsReceivableNetCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccountsReceivableNetCurrent" xlink:to="us-gaap_AccountsReceivableNetCurrent_lbl_4b52fa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccountsReceivableNetCurrent_lbl_4b52fa" xml:lang="en-US"> Accounts receivable, net of allowance for doubtful accounts of $2 and $48 at September 30, 2023 and December 31, 2022, respectively </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InventoryNet" xlink:label="us-gaap_InventoryNet"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryNet" xlink:to="us-gaap_InventoryNet_lbl_3426b4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InventoryNet_lbl_3426b4" xml:lang="en-US"> Inventory, net of reserves of $818 at September 30, 2023 and December 31, 2022 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAssetsCurrent" xlink:label="us-gaap_OtherAssetsCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherAssetsCurrent" xlink:to="us-gaap_OtherAssetsCurrent_lbl_aeee85" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherAssetsCurrent_lbl_aeee85" xml:lang="en-US"> Other current assets </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsCurrent" xlink:to="us-gaap_AssetsCurrent_lbl_5bb037" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_AssetsCurrent_lbl_5bb037" xml:lang="en-US"> Total current assets </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsCurrent" xlink:label="us-gaap_AssetsCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsCurrent" xlink:to="us-gaap_AssetsCurrent_lbl_9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AssetsCurrent_lbl_9" xml:lang="en-US"> [Assets, Current] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsNoncurrentAbstract" xlink:label="us-gaap_AssetsNoncurrentAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsNoncurrentAbstract" xlink:to="us-gaap_AssetsNoncurrentAbstract_lbl_ff00db" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AssetsNoncurrentAbstract_lbl_ff00db" xml:lang="en-US"> Non-Current Assets: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="us-gaap_PropertyPlantAndEquipmentNet"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PropertyPlantAndEquipmentNet" xlink:to="us-gaap_PropertyPlantAndEquipmentNet_lbl_c2ddae" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_lbl_c2ddae" xml:lang="en-US"> Property and equipment, net </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="us-gaap_OperatingLeaseRightOfUseAsset"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseRightOfUseAsset" xlink:to="us-gaap_OperatingLeaseRightOfUseAsset_lbl_3d3233" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLeaseRightOfUseAsset_lbl_3d3233" xml:lang="en-US"> Operating lease right-of-use assets, net of amortization </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="us-gaap_OtherAssetsNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherAssetsNoncurrent" xlink:to="us-gaap_OtherAssetsNoncurrent_lbl_80be80" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherAssetsNoncurrent_lbl_80be80" xml:lang="en-US"> Other assets </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsNoncurrent" xlink:to="us-gaap_AssetsNoncurrent_lbl_5e83c8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_AssetsNoncurrent_lbl_5e83c8" xml:lang="en-US"> Total non-current assets </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsNoncurrent" xlink:label="us-gaap_AssetsNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsNoncurrent" xlink:to="us-gaap_AssetsNoncurrent_lbl_14" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AssetsNoncurrent_lbl_14" xml:lang="en-US"> [Assets, Noncurrent] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Assets" xlink:to="us-gaap_Assets_lbl_d40e75" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_Assets_lbl_d40e75" xml:lang="en-US"> TOTAL ASSETS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Assets" xlink:label="us-gaap_Assets"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Assets" xlink:to="us-gaap_Assets_lbl_15" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_Assets_lbl_15" xml:lang="en-US"> [Assets] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:to="us-gaap_LiabilitiesAndStockholdersEquityAbstract_lbl_345a88" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesAndStockholdersEquityAbstract_lbl_345a88" xml:lang="en-US"> LIABILITIES AND STOCKHOLDERS' DEFICIT </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="us-gaap_LiabilitiesCurrentAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesCurrentAbstract" xlink:to="us-gaap_LiabilitiesCurrentAbstract_lbl_49e2bc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesCurrentAbstract_lbl_49e2bc" xml:lang="en-US"> Current Liabilities: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsPayableCurrent" xlink:label="us-gaap_AccountsPayableCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccountsPayableCurrent" xlink:to="us-gaap_AccountsPayableCurrent_lbl_06767d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccountsPayableCurrent_lbl_06767d" xml:lang="en-US"> Accounts payable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AccountPayableRelatedPartiesCurrent" xlink:label="gthp_AccountPayableRelatedPartiesCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccountPayableRelatedPartiesCurrent" xlink:to="gthp_AccountPayableRelatedPartiesCurrent_lbl_55e802" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AccountPayableRelatedPartiesCurrent_lbl_55e802" xml:lang="en-US"> Accounts payable, related parties </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="us-gaap_AccruedLiabilitiesCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedLiabilitiesCurrent" xlink:to="us-gaap_AccruedLiabilitiesCurrent_lbl_500357" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedLiabilitiesCurrent_lbl_500357" xml:lang="en-US"> Accrued liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredRevenueCurrent" xlink:label="us-gaap_DeferredRevenueCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredRevenueCurrent" xlink:to="us-gaap_DeferredRevenueCurrent_lbl_731d6d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredRevenueCurrent_lbl_731d6d" xml:lang="en-US"> Deferred revenue </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="us-gaap_OperatingLeaseLiabilityCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseLiabilityCurrent" xlink:to="us-gaap_OperatingLeaseLiabilityCurrent_lbl_9a5f90" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLeaseLiabilityCurrent_lbl_9a5f90" xml:lang="en-US"> Current portion of lease liability </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtCurrent" xlink:label="us-gaap_LongTermDebtCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtCurrent" xlink:to="us-gaap_LongTermDebtCurrent_lbl_a95f5f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtCurrent_lbl_a95f5f" xml:lang="en-US"> Current portion of long-term debt </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CurrentPortionOfLongTermDebtRelatedParties" xlink:label="gthp_CurrentPortionOfLongTermDebtRelatedParties"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CurrentPortionOfLongTermDebtRelatedParties" xlink:to="gthp_CurrentPortionOfLongTermDebtRelatedParties_lbl_c34267" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CurrentPortionOfLongTermDebtRelatedParties_lbl_c34267" xml:lang="en-US"> Current portion of long-term debt, related parties </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShortTermNonBankLoansAndNotesPayable" xlink:label="us-gaap_ShortTermNonBankLoansAndNotesPayable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShortTermNonBankLoansAndNotesPayable" xlink:to="us-gaap_ShortTermNonBankLoansAndNotesPayable_lbl_07eab7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShortTermNonBankLoansAndNotesPayable_lbl_07eab7" xml:lang="en-US"> Short-term notes payable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NotesPayableRelatedPartiesCurrent" xlink:label="gthp_NotesPayableRelatedPartiesCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NotesPayableRelatedPartiesCurrent" xlink:to="gthp_NotesPayableRelatedPartiesCurrent_lbl_396296" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NotesPayableRelatedPartiesCurrent_lbl_396296" xml:lang="en-US"> Short-term notes payable, related parties </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShortTermConvertibleNotesPayableIncludingNonconvertiblePenalty" xlink:label="gthp_ShortTermConvertibleNotesPayableIncludingNonconvertiblePenalty"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShortTermConvertibleNotesPayableIncludingNonconvertiblePenalty" xlink:to="gthp_ShortTermConvertibleNotesPayableIncludingNonconvertiblePenalty_lbl_f59956" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShortTermConvertibleNotesPayableIncludingNonconvertiblePenalty_lbl_f59956" xml:lang="en-US"> Short-term convertible debt </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesCurrent" xlink:to="us-gaap_LiabilitiesCurrent_lbl_c69797" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_LiabilitiesCurrent_lbl_c69797" xml:lang="en-US"> Total current liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesCurrent" xlink:label="us-gaap_LiabilitiesCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesCurrent" xlink:to="us-gaap_LiabilitiesCurrent_lbl_28" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesCurrent_lbl_28" xml:lang="en-US"> [Liabilities, Current] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesNoncurrentAbstract" xlink:label="us-gaap_LiabilitiesNoncurrentAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesNoncurrentAbstract" xlink:to="us-gaap_LiabilitiesNoncurrentAbstract_lbl_692e9f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesNoncurrentAbstract_lbl_692e9f" xml:lang="en-US"> Long-Term Liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="us-gaap_OperatingLeaseLiabilityNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:to="us-gaap_OperatingLeaseLiabilityNoncurrent_lbl_ef9ad9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLeaseLiabilityNoncurrent_lbl_ef9ad9" xml:lang="en-US"> Long-term lease liability </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeLiabilitiesNoncurrent" xlink:label="us-gaap_DerivativeLiabilitiesNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DerivativeLiabilitiesNoncurrent" xlink:to="us-gaap_DerivativeLiabilitiesNoncurrent_lbl_99fda2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DerivativeLiabilitiesNoncurrent_lbl_99fda2" xml:lang="en-US"> Derivative liability </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConvertibleDebtNoncurrent" xlink:label="us-gaap_ConvertibleDebtNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertibleDebtNoncurrent" xlink:to="us-gaap_ConvertibleDebtNoncurrent_lbl_6d6fc6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConvertibleDebtNoncurrent_lbl_6d6fc6" xml:lang="en-US"> Long-term convertible debt </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CurrentPortionOfLongTermDebtRelatedPartiesNonCurrent" xlink:label="gthp_CurrentPortionOfLongTermDebtRelatedPartiesNonCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CurrentPortionOfLongTermDebtRelatedPartiesNonCurrent" xlink:to="gthp_CurrentPortionOfLongTermDebtRelatedPartiesNonCurrent_lbl_68ff7b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CurrentPortionOfLongTermDebtRelatedPartiesNonCurrent_lbl_68ff7b" xml:lang="en-US"> Long-term debt, related parties </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesNoncurrent" xlink:to="us-gaap_LiabilitiesNoncurrent_lbl_1c1ef6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_LiabilitiesNoncurrent_lbl_1c1ef6" xml:lang="en-US"> Total long-term liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesNoncurrent" xlink:label="us-gaap_LiabilitiesNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesNoncurrent" xlink:to="us-gaap_LiabilitiesNoncurrent_lbl_34" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesNoncurrent_lbl_34" xml:lang="en-US"> [Liabilities, Noncurrent] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Liabilities" xlink:to="us-gaap_Liabilities_lbl_1693b5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_Liabilities_lbl_1693b5" xml:lang="en-US"> Total liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Liabilities" xlink:label="us-gaap_Liabilities"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Liabilities" xlink:to="us-gaap_Liabilities_lbl_35" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_Liabilities_lbl_35" xml:lang="en-US"> [Liabilities] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:to="us-gaap_CommitmentsAndContingenciesDisclosureAbstract_lbl_874716" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureAbstract_lbl_874716" xml:lang="en-US"> COMMITMENTS AND CONTINGENCIES (Note 7) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockValue" xlink:label="us-gaap_CommonStockValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockValue" xlink:to="us-gaap_CommonStockValue_lbl_a2285a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockValue_lbl_a2285a" xml:lang="en-US"> Common stock, $.001 par value; 500,000 shares authorized, 52,042 and 48,596 shares issued and outstanding as of September 30, 2023 and December 31, 2022, respectively. </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="us-gaap_AdditionalPaidInCapital"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AdditionalPaidInCapital" xlink:to="us-gaap_AdditionalPaidInCapital_lbl_0a4032" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AdditionalPaidInCapital_lbl_0a4032" xml:lang="en-US"> Additional paid-in capital </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_TreasuryStockValue" xlink:to="us-gaap_TreasuryStockValue_lbl_b54c9a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_TreasuryStockValue_lbl_b54c9a" xml:lang="en-US"> Treasury stock at cost </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TreasuryStockValue" xlink:label="us-gaap_TreasuryStockValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_TreasuryStockValue" xlink:to="us-gaap_TreasuryStockValue_lbl_39" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_TreasuryStockValue_lbl_39" xml:lang="en-US"> [Treasury Stock, Value] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RetainedEarningsAccumulatedDeficit" xlink:to="us-gaap_RetainedEarningsAccumulatedDeficit_lbl_bbd29e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_lbl_bbd29e" xml:lang="en-US"> Accumulated deficit </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockholdersEquityAmresh" xlink:to="gthp_StockholdersEquityAmresh_lbl_aada3a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="gthp_StockholdersEquityAmresh_lbl_aada3a" xml:lang="en-US"> Total stockholders' deficit </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StockholdersEquityAmresh" xlink:label="gthp_StockholdersEquityAmresh"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockholdersEquityAmresh" xlink:to="gthp_StockholdersEquityAmresh_lbl_41" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StockholdersEquityAmresh_lbl_41" xml:lang="en-US"> [Total stockholders' deficit] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_LiabilitiesAndStockholdersEquity_lbl_3892d0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity_lbl_3892d0" xml:lang="en-US"> TOTAL LIABILITIES AND STOCKHOLDERS' DEFICIT </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_LiabilitiesAndStockholdersEquity_lbl_42" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity_lbl_42" xml:lang="en-US"> [Liabilities and Equity] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesCOneConvertiblePreferredSharesMember" xlink:label="gthp_SeriesCOneConvertiblePreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesCOneConvertiblePreferredSharesMember" xlink:to="gthp_SeriesCOneConvertiblePreferredSharesMember_lbl_0ced43" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesCOneConvertiblePreferredSharesMember_lbl_0ced43" xml:lang="en-US"> Series C-1 Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesCTwoConvertiblePreferredSharesMember" xlink:label="gthp_SeriesCTwoConvertiblePreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesCTwoConvertiblePreferredSharesMember" xlink:to="gthp_SeriesCTwoConvertiblePreferredSharesMember_lbl_25a661" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesCTwoConvertiblePreferredSharesMember_lbl_25a661" xml:lang="en-US"> Series C-2 Convertible Preferred Shares </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AssetsCurrentAbstract" xlink:to="us-gaap_AssetsCurrentAbstract_lbl_e86577" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_AssetsCurrentAbstract_lbl_e86577" xml:lang="en-US"> CURRENT ASSETS: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsAndNotesReceivableNet" xlink:label="us-gaap_AccountsAndNotesReceivableNet"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccountsAndNotesReceivableNet" xlink:to="us-gaap_AccountsAndNotesReceivableNet_lbl_8fadba" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccountsAndNotesReceivableNet_lbl_8fadba" xml:lang="en-US"> Accounts receivable, net of allowance </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:label="us-gaap_InventoryFinishedGoodsNetOfReserves"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:to="us-gaap_InventoryFinishedGoodsNetOfReserves_lbl_67626f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InventoryFinishedGoodsNetOfReserves_lbl_67626f" xml:lang="en-US"> Inventory, net of reserves </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="us-gaap_StockholdersEquityAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockholdersEquityAbstract" xlink:to="us-gaap_StockholdersEquityAbstract_lbl_441f7d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockholdersEquityAbstract_lbl_441f7d" xml:lang="en-US"> STOCKHOLDERS' DEFICIT: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="us-gaap_CommonStockParOrStatedValuePerShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockParOrStatedValuePerShare" xlink:to="us-gaap_CommonStockParOrStatedValuePerShare_lbl_0cbbb1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockParOrStatedValuePerShare_lbl_0cbbb1" xml:lang="en-US"> Common stock, par value </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="us-gaap_CommonStockSharesAuthorized"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockSharesAuthorized" xlink:to="us-gaap_CommonStockSharesAuthorized_lbl_b49686" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockSharesAuthorized_lbl_b49686" xml:lang="en-US"> Common stock, authorized </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesIssued" xlink:label="us-gaap_CommonStockSharesIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockSharesIssued" xlink:to="us-gaap_CommonStockSharesIssued_lbl_2dd1d7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockSharesIssued_lbl_2dd1d7" xml:lang="en-US"> Common stock, issued </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="us-gaap_CommonStockSharesOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockSharesOutstanding" xlink:to="us-gaap_CommonStockSharesOutstanding_lbl_bb2d8e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockSharesOutstanding_lbl_bb2d8e" xml:lang="en-US"> Common stock, outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="us-gaap_PreferredStockParOrStatedValuePerShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockParOrStatedValuePerShare" xlink:to="us-gaap_PreferredStockParOrStatedValuePerShare_lbl_8f8d6a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockParOrStatedValuePerShare_lbl_8f8d6a" xml:lang="en-US"> Preferred stock, par value </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="us-gaap_PreferredStockSharesAuthorized"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesAuthorized" xlink:to="us-gaap_PreferredStockSharesAuthorized_lbl_882d1f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockSharesAuthorized_lbl_882d1f" xml:lang="en-US"> Preferred stock, authorized </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockLiquidationPreferences" xlink:label="gthp_PreferredStockLiquidationPreferences"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockLiquidationPreferences" xlink:to="gthp_PreferredStockLiquidationPreferences_lbl_128763" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockLiquidationPreferences_lbl_128763" xml:lang="en-US"> Preferred stock, liquidation preference </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockSharesIssued" xlink:label="us-gaap_PreferredStockSharesIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesIssued" xlink:to="us-gaap_PreferredStockSharesIssued_lbl_cccb05" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockSharesIssued_lbl_cccb05" xml:lang="en-US"> Preferred stock, issued </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="us-gaap_PreferredStockSharesOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesOutstanding" xlink:to="us-gaap_PreferredStockSharesOutstanding_lbl_91514d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockSharesOutstanding_lbl_91514d" xml:lang="en-US"> Preferred stock, outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeStatementAbstract" xlink:label="us-gaap_IncomeStatementAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeStatementAbstract" xlink:to="us-gaap_IncomeStatementAbstract_lbl_e71264" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeStatementAbstract_lbl_e71264" xml:lang="en-US"> CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Revenues" xlink:label="us-gaap_Revenues"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Revenues" xlink:to="us-gaap_Revenues_lbl_d910a3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_Revenues_lbl_d910a3" xml:lang="en-US"> Sales - devices and disposables </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CostOfGoodsAndServicesSold" xlink:label="us-gaap_CostOfGoodsAndServicesSold"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CostOfGoodsAndServicesSold" xlink:to="us-gaap_CostOfGoodsAndServicesSold_lbl_df0ada" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CostOfGoodsAndServicesSold_lbl_df0ada" xml:lang="en-US"> Cost of goods sold </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_GrossProfit" xlink:to="us-gaap_GrossProfit_lbl_20f5d1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_GrossProfit_lbl_20f5d1" xml:lang="en-US"> Gross profit </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GrossProfit" xlink:label="us-gaap_GrossProfit"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_GrossProfit" xlink:to="us-gaap_GrossProfit_lbl_4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_GrossProfit_lbl_4" xml:lang="en-US"> [Gross Profit] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="us-gaap_OperatingExpensesAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingExpensesAbstract" xlink:to="us-gaap_OperatingExpensesAbstract_lbl_bf31b5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingExpensesAbstract_lbl_bf31b5" xml:lang="en-US"> Operating expenses: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="us-gaap_ResearchAndDevelopmentExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ResearchAndDevelopmentExpense" xlink:to="us-gaap_ResearchAndDevelopmentExpense_lbl_06ef78" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ResearchAndDevelopmentExpense_lbl_06ef78" xml:lang="en-US"> Research and development </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SellingAndMarketingExpense" xlink:label="us-gaap_SellingAndMarketingExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SellingAndMarketingExpense" xlink:to="us-gaap_SellingAndMarketingExpense_lbl_cc64ef" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SellingAndMarketingExpense_lbl_cc64ef" xml:lang="en-US"> Sales and marketing </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="us-gaap_GeneralAndAdministrativeExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_GeneralAndAdministrativeExpense" xlink:to="us-gaap_GeneralAndAdministrativeExpense_lbl_4f66b7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_GeneralAndAdministrativeExpense_lbl_4f66b7" xml:lang="en-US"> General and administrative </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingExpenses" xlink:to="us-gaap_OperatingExpenses_lbl_ca36cf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_OperatingExpenses_lbl_ca36cf" xml:lang="en-US"> Total operating expenses </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpenses" xlink:label="us-gaap_OperatingExpenses"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingExpenses" xlink:to="us-gaap_OperatingExpenses_lbl_9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingExpenses_lbl_9" xml:lang="en-US"> [Operating Expenses] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingIncomeLoss" xlink:to="us-gaap_OperatingIncomeLoss_lbl_ee6b84" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_OperatingIncomeLoss_lbl_ee6b84" xml:lang="en-US"> Loss from operations </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingIncomeLoss" xlink:label="us-gaap_OperatingIncomeLoss"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingIncomeLoss" xlink:to="us-gaap_OperatingIncomeLoss_lbl_10" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingIncomeLoss_lbl_10" xml:lang="en-US"> [Operating Income (Loss)] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherNonoperatingIncomeExpenseAbstract" xlink:label="us-gaap_OtherNonoperatingIncomeExpenseAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherNonoperatingIncomeExpenseAbstract" xlink:to="us-gaap_OtherNonoperatingIncomeExpenseAbstract_lbl_adb44e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherNonoperatingIncomeExpenseAbstract_lbl_adb44e" xml:lang="en-US"> Other income (expenses): </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InterestExpense" xlink:to="us-gaap_InterestExpense_lbl_901ab3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_InterestExpense_lbl_901ab3" xml:lang="en-US"> Interest expense </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestExpense" xlink:label="us-gaap_InterestExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InterestExpense" xlink:to="us-gaap_InterestExpense_lbl_12" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InterestExpense_lbl_12" xml:lang="en-US"> [Interest Expense] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ChangeInFairValueOfDerivativeLiability" xlink:label="gthp_ChangeInFairValueOfDerivativeLiability"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ChangeInFairValueOfDerivativeLiability" xlink:to="gthp_ChangeInFairValueOfDerivativeLiability_lbl_c7782c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ChangeInFairValueOfDerivativeLiability_lbl_c7782c" xml:lang="en-US"> Change in fair value of derivative liability </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_GainFromExtinguishmentOfDebt" xlink:label="gthp_GainFromExtinguishmentOfDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_GainFromExtinguishmentOfDebt" xlink:to="gthp_GainFromExtinguishmentOfDebt_lbl_89cc82" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_GainFromExtinguishmentOfDebt_lbl_89cc82" xml:lang="en-US"> Gain from extinguishment of debt </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="us-gaap_OtherNonoperatingIncomeExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherNonoperatingIncomeExpense" xlink:to="us-gaap_OtherNonoperatingIncomeExpense_lbl_e8d255" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherNonoperatingIncomeExpense_lbl_e8d255" xml:lang="en-US"> Other income (expenses) </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NonoperatingIncomeExpense" xlink:to="us-gaap_NonoperatingIncomeExpense_lbl_426880" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_NonoperatingIncomeExpense_lbl_426880" xml:lang="en-US"> Total other income (expense) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="us-gaap_NonoperatingIncomeExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NonoperatingIncomeExpense" xlink:to="us-gaap_NonoperatingIncomeExpense_lbl_16" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NonoperatingIncomeExpense_lbl_16" xml:lang="en-US"> [Nonoperating Income (Expense)] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:to="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_lbl_6774df" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_lbl_6774df" xml:lang="en-US"> Loss before income taxes </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="us-gaap_IncomeTaxExpenseBenefit"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxExpenseBenefit" xlink:to="us-gaap_IncomeTaxExpenseBenefit_lbl_4d8c2d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxExpenseBenefit_lbl_4d8c2d" xml:lang="en-US"> Provision for income taxes </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetIncomeLoss" xlink:to="us-gaap_NetIncomeLoss_lbl_825077" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_NetIncomeLoss_lbl_825077" xml:lang="en-US"> Net loss </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss" xlink:label="us-gaap_NetIncomeLoss"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetIncomeLoss" xlink:to="us-gaap_NetIncomeLoss_lbl_19" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetIncomeLoss_lbl_19" xml:lang="en-US"> [Net Income (Loss) Attributable to Parent] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DeemedDividendForWarrantExchanges" xlink:label="gthp_DeemedDividendForWarrantExchanges"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DeemedDividendForWarrantExchanges" xlink:to="gthp_DeemedDividendForWarrantExchanges_lbl_60d5dc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DeemedDividendForWarrantExchanges_lbl_60d5dc" xml:lang="en-US"> Deemed dividend for warrant exchanges </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DividendsPreferredStock" xlink:to="us-gaap_DividendsPreferredStock_lbl_5c3681" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_DividendsPreferredStock_lbl_5c3681" xml:lang="en-US"> Preferred stock dividends </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DividendsPreferredStock" xlink:label="us-gaap_DividendsPreferredStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DividendsPreferredStock" xlink:to="us-gaap_DividendsPreferredStock_lbl_21" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DividendsPreferredStock_lbl_21" xml:lang="en-US"> [Dividends, Preferred Stock] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:to="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_lbl_d2189b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_lbl_d2189b" xml:lang="en-US"> NET LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="us-gaap_EarningsPerShareAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerShareAbstract" xlink:to="us-gaap_EarningsPerShareAbstract_lbl_f78305" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EarningsPerShareAbstract_lbl_f78305" xml:lang="en-US"> NET LOSS PER SHARE ATTRIBUTABLE TO COMMON STOCKHOLDERS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareBasic" xlink:label="us-gaap_EarningsPerShareBasic"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerShareBasic" xlink:to="us-gaap_EarningsPerShareBasic_lbl_32f67f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EarningsPerShareBasic_lbl_32f67f" xml:lang="en-US"> Basic </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="us-gaap_EarningsPerShareDiluted"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerShareDiluted" xlink:to="us-gaap_EarningsPerShareDiluted_lbl_815d6c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EarningsPerShareDiluted_lbl_815d6c" xml:lang="en-US"> Diluted </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:to="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_lbl_b4ecad" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_lbl_b4ecad" xml:lang="en-US"> Weighted average shares outstanding </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfSharesIssuedBasic" xlink:to="us-gaap_WeightedAverageNumberOfSharesIssuedBasic_lbl_f3f67e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_WeightedAverageNumberOfSharesIssuedBasic_lbl_f3f67e" xml:lang="en-US"> Basic </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfSharesIssuedBasic" xlink:label="us-gaap_WeightedAverageNumberOfSharesIssuedBasic"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfSharesIssuedBasic" xlink:to="us-gaap_WeightedAverageNumberOfSharesIssuedBasic_lbl_27" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberOfSharesIssuedBasic_lbl_27" xml:lang="en-US"> [Weighted Average Number of Shares Issued, Basic] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_lbl_57c1bc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_lbl_57c1bc" xml:lang="en-US"> Diluted </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_lbl_28" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_lbl_28" xml:lang="en-US"> [Weighted Average Number of Shares Outstanding, Diluted] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="us-gaap_StatementOfStockholdersEquityAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementOfStockholdersEquityAbstract" xlink:to="us-gaap_StatementOfStockholdersEquityAbstract_lbl_38754b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementOfStockholdersEquityAbstract_lbl_38754b" xml:lang="en-US"> CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' DEFICIT (Unaudited) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="us-gaap_StatementEquityComponentsAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementEquityComponentsAxis" xlink:to="us-gaap_StatementEquityComponentsAxis_lbl_832ac1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementEquityComponentsAxis_lbl_832ac1" xml:lang="en-US"> Equity Components [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSeriesCMember" xlink:label="gthp_PreferredStockSeriesCMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSeriesCMember" xlink:to="gthp_PreferredStockSeriesCMember_lbl_fa2fb4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSeriesCMember_lbl_fa2fb4" xml:lang="en-US"> Preferred Stock Series C [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSeriesCOneMember" xlink:label="gthp_PreferredStockSeriesCOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSeriesCOneMember" xlink:to="gthp_PreferredStockSeriesCOneMember_lbl_c4da5c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSeriesCOneMember_lbl_c4da5c" xml:lang="en-US"> Preferred Stock Series C1 [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSeriesCTwoMember" xlink:label="gthp_PreferredStockSeriesCTwoMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSeriesCTwoMember" xlink:to="gthp_PreferredStockSeriesCTwoMember_lbl_0bdbb4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSeriesCTwoMember_lbl_0bdbb4" xml:lang="en-US"> Preferred Stock Series C2 [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSeriesDMember" xlink:label="gthp_PreferredStockSeriesDMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSeriesDMember" xlink:to="gthp_PreferredStockSeriesDMember_lbl_e92c7a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSeriesDMember_lbl_e92c7a" xml:lang="en-US"> Preferred Stock Series D [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSeriesEMember" xlink:label="gthp_PreferredStockSeriesEMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSeriesEMember" xlink:to="gthp_PreferredStockSeriesEMember_lbl_8610ca" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSeriesEMember_lbl_8610ca" xml:lang="en-US"> Preferred Stock Series E [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSeriesFMember" xlink:label="gthp_PreferredStockSeriesFMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSeriesFMember" xlink:to="gthp_PreferredStockSeriesFMember_lbl_753f9f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSeriesFMember_lbl_753f9f" xml:lang="en-US"> Preferred Stock Series F [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSeriesFTwoMember" xlink:label="gthp_PreferredStockSeriesFTwoMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSeriesFTwoMember" xlink:to="gthp_PreferredStockSeriesFTwoMember_lbl_2f5a93" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSeriesFTwoMember_lbl_2f5a93" xml:lang="en-US"> Preferred Stock Series F-2 [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockMember" xlink:label="us-gaap_CommonStockMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockMember" xlink:to="us-gaap_CommonStockMember_lbl_6b20e0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockMember_lbl_6b20e0" xml:lang="en-US"> Common Stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="us-gaap_AdditionalPaidInCapitalMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AdditionalPaidInCapitalMember" xlink:to="us-gaap_AdditionalPaidInCapitalMember_lbl_344cd5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AdditionalPaidInCapitalMember_lbl_344cd5" xml:lang="en-US"> Additional Paid-In Capital [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_TreasuryStocksMember" xlink:label="gthp_TreasuryStocksMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_TreasuryStocksMember" xlink:to="gthp_TreasuryStocksMember_lbl_e8587e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_TreasuryStocksMember_lbl_e8587e" xml:lang="en-US"> Treasury Stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsMember" xlink:label="us-gaap_RetainedEarningsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RetainedEarningsMember" xlink:to="us-gaap_RetainedEarningsMember_lbl_6e7290" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RetainedEarningsMember_lbl_6e7290" xml:lang="en-US"> Accumulated Deficit [Member] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_EquitySharesIssued" xlink:to="gthp_EquitySharesIssued_lbl_b7b528" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="gthp_EquitySharesIssued_lbl_b7b528" xml:lang="en-US"> Balance, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_EquitySharesIssued" xlink:label="gthp_EquitySharesIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_EquitySharesIssued" xlink:to="gthp_EquitySharesIssued_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_EquitySharesIssued_lbl_2" xml:lang="en-US"> [Balance, shares] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockholdarsEquity" xlink:to="gthp_StockholdarsEquity_lbl_5778b8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="gthp_StockholdarsEquity_lbl_5778b8" xml:lang="en-US"> Balance, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StockholdarsEquity" xlink:label="gthp_StockholdarsEquity"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockholdarsEquity" xlink:to="gthp_StockholdarsEquity_lbl_3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StockholdarsEquity_lbl_3" xml:lang="en-US"> [Balance, amount] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockWarrantsExercisedShares" xlink:label="gthp_CommonStockWarrantsExercisedShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockWarrantsExercisedShares" xlink:to="gthp_CommonStockWarrantsExercisedShares_lbl_b2e87a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockWarrantsExercisedShares_lbl_b2e87a" xml:lang="en-US"> Common stock warrants exercised, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockWarrantsExercisedAmount" xlink:label="gthp_CommonStockWarrantsExercisedAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockWarrantsExercisedAmount" xlink:to="gthp_CommonStockWarrantsExercisedAmount_lbl_0ac357" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockWarrantsExercisedAmount_lbl_0ac357" xml:lang="en-US"> Common stock warrants exercised, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsShares" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsShares" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsShares_lbl_095b29" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsShares_lbl_095b29" xml:lang="en-US"> Issuance of common stock for payment of Series D preferred dividends, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsAmount" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsAmount" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsAmount_lbl_f0ebf3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsAmount_lbl_f0ebf3" xml:lang="en-US"> Issuance of common stock for payment of Series D preferred dividends, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsShares" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsShares" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsShares_lbl_c060c5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsShares_lbl_c060c5" xml:lang="en-US"> Issuance of common stock for payment of Series E preferred dividends, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsAmount" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsAmount" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsAmount_lbl_2158dd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsAmount_lbl_2158dd" xml:lang="en-US"> Issuance of common stock for payment of Series E preferred dividends, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesDPreferredStockToCommonStock" xlink:label="gthp_ConversionOfSeriesDPreferredStockToCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesDPreferredStockToCommonStock" xlink:to="gthp_ConversionOfSeriesDPreferredStockToCommonStock_lbl_57b2e0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesDPreferredStockToCommonStock_lbl_57b2e0" xml:lang="en-US"> Conversion of Series D preferred stock to common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsShares" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsShares" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsShares_lbl_fd8faf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsShares_lbl_fd8faf" xml:lang="en-US"> Issuance of common stock for payment of Series F preferred dividends, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesEPreferredStockToCommonStockShares" xlink:label="gthp_ConversionOfSeriesEPreferredStockToCommonStockShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesEPreferredStockToCommonStockShares" xlink:to="gthp_ConversionOfSeriesEPreferredStockToCommonStockShares_lbl_e4acd2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesEPreferredStockToCommonStockShares_lbl_e4acd2" xml:lang="en-US"> Conversion of Series E preferred stock to common stock, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsAmount" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsAmount" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsAmount_lbl_e71fb4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesFPreferredDividendsAmount_lbl_e71fb4" xml:lang="en-US"> Issuance of common stock for payment of Series F preferred dividends, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesEPreferredStockToCommonStockAmount" xlink:label="gthp_ConversionOfSeriesEPreferredStockToCommonStockAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesEPreferredStockToCommonStockAmount" xlink:to="gthp_ConversionOfSeriesEPreferredStockToCommonStockAmount_lbl_673c8a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesEPreferredStockToCommonStockAmount_lbl_673c8a" xml:lang="en-US"> Conversion of Series E preferred stock to common stock, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsShares" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsShares" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsShares_lbl_b0b939" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsShares_lbl_b0b939" xml:lang="en-US"> Issuance of common stock for payment of Series F-2 preferred dividends, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesFPreferredStockToCommonStock" xlink:label="gthp_ConversionOfSeriesFPreferredStockToCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesFPreferredStockToCommonStock" xlink:to="gthp_ConversionOfSeriesFPreferredStockToCommonStock_lbl_f9ece3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesFPreferredStockToCommonStock_lbl_f9ece3" xml:lang="en-US"> Conversion of Series F preferred stock to common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsAmount" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsAmount" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsAmount_lbl_df0df3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesF2PreferredDividendsAmount_lbl_df0df3" xml:lang="en-US"> Issuance of common stock for payment of Series F-2 preferred dividends, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesF2PreferredStockToCommonStockShares" xlink:label="gthp_ConversionOfSeriesF2PreferredStockToCommonStockShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesF2PreferredStockToCommonStockShares" xlink:to="gthp_ConversionOfSeriesF2PreferredStockToCommonStockShares_lbl_a3336f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesF2PreferredStockToCommonStockShares_lbl_a3336f" xml:lang="en-US"> Conversion of Series F-2 preferred stock to common stock, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfInterestShares" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfInterestShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfInterestShares" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfInterestShares_lbl_a40a3c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfInterestShares_lbl_a40a3c" xml:lang="en-US"> Issuance of common stock for payment of interest, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesF2PreferredStockToCommonStockAmount" xlink:label="gthp_ConversionOfSeriesF2PreferredStockToCommonStockAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesF2PreferredStockToCommonStockAmount" xlink:to="gthp_ConversionOfSeriesF2PreferredStockToCommonStockAmount_lbl_944999" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesF2PreferredStockToCommonStockAmount_lbl_944999" xml:lang="en-US"> Conversion of Series F-2 preferred stock to common stock, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfInterestAmount" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfInterestAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfInterestAmount" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfInterestAmount_lbl_3a44f0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfInterestAmount_lbl_3a44f0" xml:lang="en-US"> Issuance of common stock for payment of interest, amount </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_Stockbasedcompensationn" xlink:to="gthp_Stockbasedcompensationn_lbl_125773" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_Stockbasedcompensationn_lbl_125773" xml:lang="en-US"> Stock-based compensation </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_Stockbasedcompensationn" xlink:label="gthp_Stockbasedcompensationn"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_Stockbasedcompensationn" xlink:to="gthp_Stockbasedcompensationn_lbl_22" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_Stockbasedcompensationn_lbl_22" xml:lang="en-US"> [Stock-based compensation] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsShares" xlink:label="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsShares" xlink:to="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsShares_lbl_a1ded1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsShares_lbl_a1ded1" xml:lang="en-US"> Issuance of common stock for Series F and Series F-2 one-time 15% dividends, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuranceOfWarrrantsToConsultants" xlink:label="gthp_IssuranceOfWarrrantsToConsultants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuranceOfWarrrantsToConsultants" xlink:to="gthp_IssuranceOfWarrrantsToConsultants_lbl_2b9e6e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuranceOfWarrrantsToConsultants_lbl_2b9e6e" xml:lang="en-US"> Issurance of warrrants to consultants </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsAmount" xlink:label="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsAmount" xlink:to="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsAmount_lbl_9f83d1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForSeriesFAndSeriesF2OneTime15DividendsAmount_lbl_9f83d1" xml:lang="en-US"> Issuance of common stock for Series F and Series F-2 one-time 15% dividends, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_Accruedpreferreddividends" xlink:label="gthp_Accruedpreferreddividends"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_Accruedpreferreddividends" xlink:to="gthp_Accruedpreferreddividends_lbl_c45457" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_Accruedpreferreddividends_lbl_c45457" xml:lang="en-US"> Accrued preferred dividends </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesDPreferredStockToCommonStockShares" xlink:label="gthp_ConversionOfSeriesDPreferredStockToCommonStockShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesDPreferredStockToCommonStockShares" xlink:to="gthp_ConversionOfSeriesDPreferredStockToCommonStockShares_lbl_fcde97" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesDPreferredStockToCommonStockShares_lbl_fcde97" xml:lang="en-US"> Conversion of Series D preferred stock to common stock, shares </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NetIncomeLosses" xlink:to="gthp_NetIncomeLosses_lbl_3d0d0c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_NetIncomeLosses_lbl_3d0d0c" xml:lang="en-US"> Net loss </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NetIncomeLosses" xlink:label="gthp_NetIncomeLosses"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NetIncomeLosses" xlink:to="gthp_NetIncomeLosses_lbl_28" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NetIncomeLosses_lbl_28" xml:lang="en-US"> [Net loss] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesFPreferredStockToCommonStockShares" xlink:label="gthp_ConversionOfSeriesFPreferredStockToCommonStockShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesFPreferredStockToCommonStockShares" xlink:to="gthp_ConversionOfSeriesFPreferredStockToCommonStockShares_lbl_3057ea" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesFPreferredStockToCommonStockShares_lbl_3057ea" xml:lang="en-US"> Conversion of Series F preferred stock to common stock, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesFPreferredStockToCommonStockAmount" xlink:label="gthp_ConversionOfSeriesFPreferredStockToCommonStockAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesFPreferredStockToCommonStockAmount" xlink:to="gthp_ConversionOfSeriesFPreferredStockToCommonStockAmount_lbl_80a374" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesFPreferredStockToCommonStockAmount_lbl_80a374" xml:lang="en-US"> Conversion of Series F preferred stock to common stock, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuancesOfCommonStockToInvestorsShares" xlink:label="gthp_IssuancesOfCommonStockToInvestorsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuancesOfCommonStockToInvestorsShares" xlink:to="gthp_IssuancesOfCommonStockToInvestorsShares_lbl_6c9abd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuancesOfCommonStockToInvestorsShares_lbl_6c9abd" xml:lang="en-US"> Issuances of common stock to investors, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuancesOfCommonStockToInvestorsAmount" xlink:label="gthp_IssuancesOfCommonStockToInvestorsAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuancesOfCommonStockToInvestorsAmount" xlink:to="gthp_IssuancesOfCommonStockToInvestorsAmount_lbl_61538f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuancesOfCommonStockToInvestorsAmount_lbl_61538f" xml:lang="en-US"> Issuances of common stock to investors, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ProceedsFromIssuanceOfWarrantsNew" xlink:label="gthp_ProceedsFromIssuanceOfWarrantsNew"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ProceedsFromIssuanceOfWarrantsNew" xlink:to="gthp_ProceedsFromIssuanceOfWarrantsNew_lbl_865189" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ProceedsFromIssuanceOfWarrantsNew_lbl_865189" xml:lang="en-US"> Issuance of warrants to investors </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesF2PreferredStockToCommonStockSharesShares" xlink:label="gthp_ConversionOfSeriesF2PreferredStockToCommonStockSharesShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesF2PreferredStockToCommonStockSharesShares" xlink:to="gthp_ConversionOfSeriesF2PreferredStockToCommonStockSharesShares_lbl_b8e557" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesF2PreferredStockToCommonStockSharesShares_lbl_b8e557" xml:lang="en-US"> Conversion of Series F-2 preferred stock to common stock, shares, shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_Stockbasedcompensation" xlink:label="gthp_Stockbasedcompensation"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_Stockbasedcompensation" xlink:to="gthp_Stockbasedcompensation_lbl_2b45d9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_Stockbasedcompensation_lbl_2b45d9" xml:lang="en-US"> Stock-based compensation </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuancesOfWarrantsToConsultants" xlink:label="gthp_IssuancesOfWarrantsToConsultants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuancesOfWarrantsToConsultants" xlink:to="gthp_IssuancesOfWarrantsToConsultants_lbl_cad324" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuancesOfWarrantsToConsultants_lbl_cad324" xml:lang="en-US"> Issuances of warrants to consultants </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AccruedPreferredDividents" xlink:label="gthp_AccruedPreferredDividents"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccruedPreferredDividents" xlink:to="gthp_AccruedPreferredDividents_lbl_04d206" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AccruedPreferredDividents_lbl_04d206" xml:lang="en-US"> Accrued Preferred Dividents </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceAmount" xlink:label="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceAmount" xlink:to="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceAmount_lbl_d699e4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceAmount_lbl_d699e4" xml:lang="en-US"> Settlement of previously accrued professional fees through common stock issuance, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ImpactOfWarrantExchanges" xlink:label="gthp_ImpactOfWarrantExchanges"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ImpactOfWarrantExchanges" xlink:to="gthp_ImpactOfWarrantExchanges_lbl_95f6c5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ImpactOfWarrantExchanges_lbl_95f6c5" xml:lang="en-US"> Impact of warrant exchanges </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceShares" xlink:label="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceShares" xlink:to="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceShares_lbl_c82036" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuanceShares_lbl_c82036" xml:lang="en-US"> Settlement of previously accrued professional fees through common stock issuance, shares </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_EquitySharesIssued" xlink:to="gthp_EquitySharesIssued_lbl_1bff22" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="gthp_EquitySharesIssued_lbl_1bff22" xml:lang="en-US"> Balance, shares </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockholdarsEquity" xlink:to="gthp_StockholdarsEquity_lbl_ff1fd5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="gthp_StockholdarsEquity_lbl_ff1fd5" xml:lang="en-US"> Balance, amount </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="us-gaap_StatementOfCashFlowsAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StatementOfCashFlowsAbstract" xlink:to="us-gaap_StatementOfCashFlowsAbstract_lbl_3254b1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StatementOfCashFlowsAbstract_lbl_3254b1" xml:lang="en-US"> CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_lbl_564886" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_lbl_564886" xml:lang="en-US"> CASH FLOWS FROM OPERATING ACTIVITIES: </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetIncomeLoss" xlink:to="us-gaap_NetIncomeLoss_lbl_3c45ba" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_NetIncomeLoss_lbl_3c45ba" xml:lang="en-US"> Net loss </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_lbl_4cde8a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_lbl_4cde8a" xml:lang="en-US"> Adjustments to reconcile net loss to net cash used in operating activities: </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_BadDebtExpense" xlink:label="gthp_BadDebtExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_BadDebtExpense" xlink:to="gthp_BadDebtExpense_lbl_2f6c7b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_BadDebtExpense_lbl_2f6c7b" xml:lang="en-US"> Bad debt expense </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Depreciation" xlink:label="us-gaap_Depreciation"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Depreciation" xlink:to="us-gaap_Depreciation_lbl_21ee90" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_Depreciation_lbl_21ee90" xml:lang="en-US"> Depreciation </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:label="us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:to="us-gaap_AmortizationOfFinancingCostsAndDiscounts_lbl_5bb558" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AmortizationOfFinancingCostsAndDiscounts_lbl_5bb558" xml:lang="en-US"> Amortization of debt issuance costs and discounts </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensation" xlink:to="us-gaap_ShareBasedCompensation_lbl_d730ea" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ShareBasedCompensation_lbl_d730ea" xml:lang="en-US"> Stock-based compensation </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensation" xlink:label="us-gaap_ShareBasedCompensation"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensation" xlink:to="us-gaap_ShareBasedCompensation_lbl_8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensation_lbl_8" xml:lang="en-US"> [Share-Based Payment Arrangement, Noncash Expense] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ChangeInFairValueOfDerivativeLiability" xlink:to="gthp_ChangeInFairValueOfDerivativeLiability_lbl_7dde01" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="gthp_ChangeInFairValueOfDerivativeLiability_lbl_7dde01" xml:lang="en-US"> Change in fair value of derivative liability </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense" xlink:label="us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense" xlink:to="us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_lbl_89409a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_lbl_89409a" xml:lang="en-US"> Amortization of lease right-of-use-asset </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_GainFromForgivenessOfDebt" xlink:to="gthp_GainFromForgivenessOfDebt_lbl_9137ec" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="gthp_GainFromForgivenessOfDebt_lbl_9137ec" xml:lang="en-US"> Gain from forgiveness of debt </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_GainFromForgivenessOfDebt" xlink:label="gthp_GainFromForgivenessOfDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_GainFromForgivenessOfDebt" xlink:to="gthp_GainFromForgivenessOfDebt_lbl_11" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_GainFromForgivenessOfDebt_lbl_11" xml:lang="en-US"> [Gain from forgiveness of debt] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherNoncashIncomeExpense" xlink:to="us-gaap_OtherNoncashIncomeExpense_lbl_05d6bd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_OtherNoncashIncomeExpense_lbl_05d6bd" xml:lang="en-US"> Other non-cash expenses </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherNoncashIncomeExpense" xlink:label="us-gaap_OtherNoncashIncomeExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherNoncashIncomeExpense" xlink:to="us-gaap_OtherNoncashIncomeExpense_lbl_12" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherNoncashIncomeExpense_lbl_12" xml:lang="en-US"> [Other Noncash Income (Expense)] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:to="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_lbl_5e6280" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_lbl_5e6280" xml:lang="en-US"> Change in operating assets and liabilities: </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:to="us-gaap_IncreaseDecreaseInAccountsReceivable_lbl_bb44ac" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_IncreaseDecreaseInAccountsReceivable_lbl_bb44ac" xml:lang="en-US"> Accounts receivable </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="us-gaap_IncreaseDecreaseInAccountsReceivable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:to="us-gaap_IncreaseDecreaseInAccountsReceivable_lbl_14" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInAccountsReceivable_lbl_14" xml:lang="en-US"> [Increase (Decrease) in Accounts Receivable] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInInventories" xlink:to="us-gaap_IncreaseDecreaseInInventories_lbl_c5a041" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_IncreaseDecreaseInInventories_lbl_c5a041" xml:lang="en-US"> Inventory </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="us-gaap_IncreaseDecreaseInInventories"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInInventories" xlink:to="us-gaap_IncreaseDecreaseInInventories_lbl_15" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInInventories_lbl_15" xml:lang="en-US"> [Increase (Decrease) in Inventories] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInOtherCurrentAssets" xlink:to="us-gaap_IncreaseDecreaseInOtherCurrentAssets_lbl_a9ab95" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_IncreaseDecreaseInOtherCurrentAssets_lbl_a9ab95" xml:lang="en-US"> Other current assets </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOtherCurrentAssets" xlink:label="us-gaap_IncreaseDecreaseInOtherCurrentAssets"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInOtherCurrentAssets" xlink:to="us-gaap_IncreaseDecreaseInOtherCurrentAssets_lbl_16" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInOtherCurrentAssets_lbl_16" xml:lang="en-US"> [Increase (Decrease) in Other Current Assets] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:to="us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_lbl_4b8615" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_lbl_4b8615" xml:lang="en-US"> Accounts payable and accrued liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOperatingLeaseLiability" xlink:label="us-gaap_IncreaseDecreaseInOperatingLeaseLiability"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInOperatingLeaseLiability" xlink:to="us-gaap_IncreaseDecreaseInOperatingLeaseLiability_lbl_e043aa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInOperatingLeaseLiability_lbl_e043aa" xml:lang="en-US"> Lease liabilities </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:to="us-gaap_IncreaseDecreaseInDeferredRevenue_lbl_4ad393" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_IncreaseDecreaseInDeferredRevenue_lbl_4ad393" xml:lang="en-US"> Deferred revenue </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:label="us-gaap_IncreaseDecreaseInDeferredRevenue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:to="us-gaap_IncreaseDecreaseInDeferredRevenue_lbl_19" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncreaseDecreaseInDeferredRevenue_lbl_19" xml:lang="en-US"> [Increase (Decrease) in Deferred Revenue] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl_e0865a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl_e0865a" xml:lang="en-US"> NET CASH USED IN OPERATING ACTIVITIES </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl_20" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl_20" xml:lang="en-US"> [Net Cash Provided by (Used in) Operating Activities] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_lbl_f3eb7e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_lbl_f3eb7e" xml:lang="en-US"> CASH FLOWS FROM INVESTING ACTIVITIES: </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:to="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl_efc9a0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl_efc9a0" xml:lang="en-US"> Purchase of property and equipment </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:to="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl_22" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl_22" xml:lang="en-US"> [Payments to Acquire Property, Plant, and Equipment] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_lbl_389b34" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_lbl_389b34" xml:lang="en-US"> CASH FLOWS FROM FINANCING ACTIVITIES: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="us-gaap_ProceedsFromWarrantExercises"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromWarrantExercises" xlink:to="us-gaap_ProceedsFromWarrantExercises_lbl_69c88d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromWarrantExercises_lbl_69c88d" xml:lang="en-US"> Proceeds from warrant exercises </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RepaymentsOfNotesPayable" xlink:to="us-gaap_RepaymentsOfNotesPayable_lbl_9bfb97" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_RepaymentsOfNotesPayable_lbl_9bfb97" xml:lang="en-US"> Payments made on notes payable </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RepaymentsOfNotesPayable" xlink:label="us-gaap_RepaymentsOfNotesPayable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RepaymentsOfNotesPayable" xlink:to="us-gaap_RepaymentsOfNotesPayable_lbl_25" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RepaymentsOfNotesPayable_lbl_25" xml:lang="en-US"> [Repayments of Notes Payable] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="us-gaap_ProceedsFromIssuanceOfCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:to="us-gaap_ProceedsFromIssuanceOfCommonStock_lbl_21778e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromIssuanceOfCommonStock_lbl_21778e" xml:lang="en-US"> Proceeds from issuance of common stock, net of costs </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ProceedsFromIssuancesOfWarrantsNetOfCosts" xlink:label="gthp_ProceedsFromIssuancesOfWarrantsNetOfCosts"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ProceedsFromIssuancesOfWarrantsNetOfCosts" xlink:to="gthp_ProceedsFromIssuancesOfWarrantsNetOfCosts_lbl_d1ca34" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ProceedsFromIssuancesOfWarrantsNetOfCosts_lbl_d1ca34" xml:lang="en-US"> Proceeds from issuances of warrants, net of costs </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl_c77851" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl_c77851" xml:lang="en-US"> NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl_28" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl_28" xml:lang="en-US"> [Net Cash Provided by (Used in) Financing Activities] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_lbl_dd1933" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_lbl_dd1933" xml:lang="en-US"> NET CHANGE IN CASH </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_lbl_29" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_lbl_29" xml:lang="en-US"> [Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl_74e23c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl_74e23c" xml:lang="en-US"> Cash at beginning of period </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl_30" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl_30" xml:lang="en-US"> [Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl_6a8ebe" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl_6a8ebe" xml:lang="en-US"> CASH AT END OF PERIOD </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SupplementalCashFlowElementsAbstract" xlink:label="us-gaap_SupplementalCashFlowElementsAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SupplementalCashFlowElementsAbstract" xlink:to="us-gaap_SupplementalCashFlowElementsAbstract_lbl_2df903" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SupplementalCashFlowElementsAbstract_lbl_2df903" xml:lang="en-US"> SUPPLEMENTAL DISCLOSURE FOR OPERATING ACTIVITIES: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestPaid" xlink:label="us-gaap_InterestPaid"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InterestPaid" xlink:to="us-gaap_InterestPaid_lbl_7f07cc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InterestPaid_lbl_7f07cc" xml:lang="en-US"> Cash paid for interest </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:label="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:to="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_lbl_5e1ad9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_lbl_5e1ad9" xml:lang="en-US"> SUPPLEMENTAL DISCLOSURE FOR NON-CASH INVESTING AND FINANCING ACTIVITIES: </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DividendsPreferredStockStock" xlink:label="us-gaap_DividendsPreferredStockStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DividendsPreferredStockStock" xlink:to="us-gaap_DividendsPreferredStockStock_lbl_132573" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DividendsPreferredStockStock_lbl_132573" xml:lang="en-US"> Dividends on preferred stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DeemedDividendsForWarrantExchanges" xlink:label="gthp_DeemedDividendsForWarrantExchanges"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DeemedDividendsForWarrantExchanges" xlink:to="gthp_DeemedDividendsForWarrantExchanges_lbl_68ad34" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DeemedDividendsForWarrantExchanges_lbl_68ad34" xml:lang="en-US"> Deemed dividends for warrant exchanges </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SettlementOfInterestThroughCommonStockIssuance" xlink:label="gthp_SettlementOfInterestThroughCommonStockIssuance"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SettlementOfInterestThroughCommonStockIssuance" xlink:to="gthp_SettlementOfInterestThroughCommonStockIssuance_lbl_66bcb4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SettlementOfInterestThroughCommonStockIssuance_lbl_66bcb4" xml:lang="en-US"> Settlement of interest through common stock issuance </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SettlementOfDividendsThroughCommonStockIssuance" xlink:label="gthp_SettlementOfDividendsThroughCommonStockIssuance"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SettlementOfDividendsThroughCommonStockIssuance" xlink:to="gthp_SettlementOfDividendsThroughCommonStockIssuance_lbl_d09d32" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SettlementOfDividendsThroughCommonStockIssuance_lbl_d09d32" xml:lang="en-US"> Settlement of dividends through common stock issuance </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuance" xlink:label="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuance"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuance" xlink:to="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuance_lbl_db4c03" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SettlementOfPreviouslyAccruedProfessionalFeesThroughCommonStockIssuance_lbl_db4c03" xml:lang="en-US"> Settlement of previously accrued professional fees through common stock issuance </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesDPreferredSharesIntoCommonStock" xlink:label="gthp_ConversionOfSeriesDPreferredSharesIntoCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesDPreferredSharesIntoCommonStock" xlink:to="gthp_ConversionOfSeriesDPreferredSharesIntoCommonStock_lbl_0b6575" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesDPreferredSharesIntoCommonStock_lbl_0b6575" xml:lang="en-US"> Conversion of Series D preferred shares into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesEPreferredSharesIntoCommonStock" xlink:label="gthp_ConversionOfSeriesEPreferredSharesIntoCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesEPreferredSharesIntoCommonStock" xlink:to="gthp_ConversionOfSeriesEPreferredSharesIntoCommonStock_lbl_45d141" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesEPreferredSharesIntoCommonStock_lbl_45d141" xml:lang="en-US"> Conversion of Series E preferred shares into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesFPreferredSharesIntoCommonStock" xlink:label="gthp_ConversionOfSeriesFPreferredSharesIntoCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesFPreferredSharesIntoCommonStock" xlink:to="gthp_ConversionOfSeriesFPreferredSharesIntoCommonStock_lbl_16d407" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesFPreferredSharesIntoCommonStock_lbl_16d407" xml:lang="en-US"> Conversion of Series F preferred shares into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionOfSeriesF2PreferredSharesIntoCommonStock" xlink:label="gthp_ConversionOfSeriesF2PreferredSharesIntoCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionOfSeriesF2PreferredSharesIntoCommonStock" xlink:to="gthp_ConversionOfSeriesF2PreferredSharesIntoCommonStock_lbl_ee4b3f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionOfSeriesF2PreferredSharesIntoCommonStock_lbl_ee4b3f" xml:lang="en-US"> Conversion of Series F-2 preferred shares into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DirectorsAndOfficersInsuranceObtainedWithFinancing" xlink:label="gthp_DirectorsAndOfficersInsuranceObtainedWithFinancing"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DirectorsAndOfficersInsuranceObtainedWithFinancing" xlink:to="gthp_DirectorsAndOfficersInsuranceObtainedWithFinancing_lbl_073f8b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DirectorsAndOfficersInsuranceObtainedWithFinancing_lbl_073f8b" xml:lang="en-US"> Directors and Officers insurance obtained with financing </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_lbl_5811d2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_lbl_5811d2" xml:lang="en-US"> ORGANIZATION BACKGROUND AND BASIS OF PRESENTATION </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock" xlink:label="us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock" xlink:to="us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_lbl_b8d1a6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_lbl_b8d1a6" xml:lang="en-US"> ORGANIZATION, BACKGROUND, AND BASIS OF PRESENTATION </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="us-gaap_AccountingPoliciesAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccountingPoliciesAbstract" xlink:to="us-gaap_AccountingPoliciesAbstract_lbl_a5c56c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccountingPoliciesAbstract_lbl_a5c56c" xml:lang="en-US"> SIGNIFICANT ACCOUNTING POLICIES </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SignificantAccountingPoliciesTextBlock" xlink:to="us-gaap_SignificantAccountingPoliciesTextBlock_lbl_3e0c8a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_SignificantAccountingPoliciesTextBlock_lbl_3e0c8a" xml:lang="en-US"> SIGNIFICANT ACCOUNTING POLICIES </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="us-gaap_SignificantAccountingPoliciesTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SignificantAccountingPoliciesTextBlock" xlink:to="us-gaap_SignificantAccountingPoliciesTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SignificantAccountingPoliciesTextBlock_lbl_2" xml:lang="en-US"> Significant Accounting Policies [Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="us-gaap_FairValueDisclosuresAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueDisclosuresAbstract" xlink:to="us-gaap_FairValueDisclosuresAbstract_lbl_646603" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueDisclosuresAbstract_lbl_646603" xml:lang="en-US"> FAIR VALUE OF FINANCIAL INSTRUMENTS </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FinancialInstrumentsDisclosureTextBlock" xlink:to="us-gaap_FinancialInstrumentsDisclosureTextBlock_lbl_c8588e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_FinancialInstrumentsDisclosureTextBlock_lbl_c8588e" xml:lang="en-US"> FAIR VALUE OF FINANCIAL INSTRUMENTS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FinancialInstrumentsDisclosureTextBlock" xlink:label="us-gaap_FinancialInstrumentsDisclosureTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FinancialInstrumentsDisclosureTextBlock" xlink:to="us-gaap_FinancialInstrumentsDisclosureTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FinancialInstrumentsDisclosureTextBlock_lbl_2" xml:lang="en-US"> Financial Instruments Disclosure [Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:to="us-gaap_StockholdersEquityNoteDisclosureTextBlock_lbl_6f81c3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockholdersEquityNoteDisclosureTextBlock_lbl_6f81c3" xml:lang="en-US"> STOCKHOLDERS' DEFICIT </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:to="us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_lbl_5c6f3a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_lbl_5c6f3a" xml:lang="en-US"> STOCK OPTIONS </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock" xlink:to="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_lbl_ceef17" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_lbl_ceef17" xml:lang="en-US"> STOCK OPTIONS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock" xlink:label="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock" xlink:to="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_lbl_2" xml:lang="en-US"> Share-Based Payment Arrangement [Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LitigationAndClaimsAbstract" xlink:label="gthp_LitigationAndClaimsAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LitigationAndClaimsAbstract" xlink:to="gthp_LitigationAndClaimsAbstract_lbl_7564c7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LitigationAndClaimsAbstract_lbl_7564c7" xml:lang="en-US"> LITIGATION AND CLAIMS </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LitigationAndClaimsTextBlock" xlink:to="gthp_LitigationAndClaimsTextBlock_lbl_6cd5d5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_LitigationAndClaimsTextBlock_lbl_6cd5d5" xml:lang="en-US"> LITIGATION AND CLAIMS </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LitigationAndClaimsTextBlock" xlink:label="gthp_LitigationAndClaimsTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LitigationAndClaimsTextBlock" xlink:to="gthp_LitigationAndClaimsTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LitigationAndClaimsTextBlock_lbl_2" xml:lang="en-US"> [LITIGATION AND CLAIMS] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:to="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_lbl_8c8c31" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_lbl_8c8c31" xml:lang="en-US"> COMMITMENTS AND CONTINGENCIES </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:to="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_lbl_2" xml:lang="en-US"> Commitments and Contingencies Disclosure [Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NotesPayableAbstract" xlink:label="us-gaap_NotesPayableAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NotesPayableAbstract" xlink:to="us-gaap_NotesPayableAbstract_lbl_7abd06" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NotesPayableAbstract_lbl_7abd06" xml:lang="en-US"> NOTES PAYABLE </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtDisclosureTextBlock" xlink:to="us-gaap_DebtDisclosureTextBlock_lbl_4ad03b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_DebtDisclosureTextBlock_lbl_4ad03b" xml:lang="en-US"> NOTES PAYABLE </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="us-gaap_DebtDisclosureTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtDisclosureTextBlock" xlink:to="us-gaap_DebtDisclosureTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtDisclosureTextBlock_lbl_2" xml:lang="en-US"> Debt Disclosure [Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="us-gaap_DebtDisclosureAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtDisclosureAbstract" xlink:to="us-gaap_DebtDisclosureAbstract_lbl_b18468" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtDisclosureAbstract_lbl_b18468" xml:lang="en-US"> AUCTUS CONVERTIBLE DEBT </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AuctusConvertibleDebtDisclsoureTextBlock" xlink:to="gthp_AuctusConvertibleDebtDisclsoureTextBlock_lbl_17c443" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_AuctusConvertibleDebtDisclsoureTextBlock_lbl_17c443" xml:lang="en-US"> AUCTUS CONVERTIBLE DEBT </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AuctusConvertibleDebtDisclsoureTextBlock" xlink:label="gthp_AuctusConvertibleDebtDisclsoureTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AuctusConvertibleDebtDisclsoureTextBlock" xlink:to="gthp_AuctusConvertibleDebtDisclsoureTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AuctusConvertibleDebtDisclsoureTextBlock_lbl_2" xml:lang="en-US"> [AUCTUS CONVERTIBLE DEBT] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtAbstract" xlink:label="us-gaap_LongTermDebtAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtAbstract" xlink:to="us-gaap_LongTermDebtAbstract_lbl_e533be" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtAbstract_lbl_e533be" xml:lang="en-US"> LONG TERM DEBT </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtTextBlock" xlink:label="us-gaap_LongTermDebtTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtTextBlock" xlink:to="us-gaap_LongTermDebtTextBlock_lbl_7633b3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtTextBlock_lbl_7633b3" xml:lang="en-US"> LONG-TERM DEBT </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerShareTextBlock" xlink:to="us-gaap_EarningsPerShareTextBlock_lbl_183c72" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_EarningsPerShareTextBlock_lbl_183c72" xml:lang="en-US"> INCOME (LOSS) PER SHARE OF COMMON STOCK </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="us-gaap_EarningsPerShareTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EarningsPerShareTextBlock" xlink:to="us-gaap_EarningsPerShareTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EarningsPerShareTextBlock_lbl_2" xml:lang="en-US"> Earnings Per Share [Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="us-gaap_SubsequentEventsAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SubsequentEventsAbstract" xlink:to="us-gaap_SubsequentEventsAbstract_lbl_316023" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SubsequentEventsAbstract_lbl_316023" xml:lang="en-US"> SUBSEQUENT EVENTS </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SubsequentEventsTextBlock" xlink:to="us-gaap_SubsequentEventsTextBlock_lbl_650f3d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_SubsequentEventsTextBlock_lbl_650f3d" xml:lang="en-US"> SUBSEQUENT EVENTS </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventsTextBlock" xlink:label="us-gaap_SubsequentEventsTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SubsequentEventsTextBlock" xlink:to="us-gaap_SubsequentEventsTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SubsequentEventsTextBlock_lbl_2" xml:lang="en-US"> Subsequent Events [Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_UseOfEstimates" xlink:label="us-gaap_UseOfEstimates"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_UseOfEstimates" xlink:to="us-gaap_UseOfEstimates_lbl_284499" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_UseOfEstimates_lbl_284499" xml:lang="en-US"> Use of Estimates </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:to="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_lbl_abb6bc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_lbl_abb6bc" xml:lang="en-US"> Accounting Standard Updates </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:label="us-gaap_CashAndCashEquivalentsPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:to="us-gaap_CashAndCashEquivalentsPolicyTextBlock_lbl_1cb93c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CashAndCashEquivalentsPolicyTextBlock_lbl_1cb93c" xml:lang="en-US"> Cash Equivalents </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TradeAndOtherAccountsReceivablePolicy" xlink:label="us-gaap_TradeAndOtherAccountsReceivablePolicy"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_TradeAndOtherAccountsReceivablePolicy" xlink:to="us-gaap_TradeAndOtherAccountsReceivablePolicy_lbl_36fa9a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_TradeAndOtherAccountsReceivablePolicy_lbl_36fa9a" xml:lang="en-US"> Accounts Receivable </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConcentrationRiskCreditRisk" xlink:label="us-gaap_ConcentrationRiskCreditRisk"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConcentrationRiskCreditRisk" xlink:to="us-gaap_ConcentrationRiskCreditRisk_lbl_245e7b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConcentrationRiskCreditRisk_lbl_245e7b" xml:lang="en-US"> Concentrations of Credit Risk </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InventoryPolicyTextBlock" xlink:label="us-gaap_InventoryPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryPolicyTextBlock" xlink:to="us-gaap_InventoryPolicyTextBlock_lbl_fc4926" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InventoryPolicyTextBlock_lbl_fc4926" xml:lang="en-US"> Inventory Valuation </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:label="us-gaap_PropertyPlantAndEquipmentPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:to="us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_lbl_6178cc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_lbl_6178cc" xml:lang="en-US"> Property and Equipment </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtPolicyTextBlock" xlink:label="us-gaap_DebtPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtPolicyTextBlock" xlink:to="us-gaap_DebtPolicyTextBlock_lbl_b36f24" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtPolicyTextBlock_lbl_b36f24" xml:lang="en-US"> Debt Issuance Costs </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PatentCostsPolicyTextBlock" xlink:label="gthp_PatentCostsPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PatentCostsPolicyTextBlock" xlink:to="gthp_PatentCostsPolicyTextBlock_lbl_0cf334" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PatentCostsPolicyTextBlock_lbl_0cf334" xml:lang="en-US"> Patent Costs (Principally Legal Fees) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeLeasesPolicyTextBlock" xlink:label="us-gaap_LesseeLeasesPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeLeasesPolicyTextBlock" xlink:to="us-gaap_LesseeLeasesPolicyTextBlock_lbl_0cf2d1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LesseeLeasesPolicyTextBlock_lbl_0cf2d1" xml:lang="en-US"> Leases </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AccruedLiabilitiesPolicyTextBlock" xlink:label="gthp_AccruedLiabilitiesPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccruedLiabilitiesPolicyTextBlock" xlink:to="gthp_AccruedLiabilitiesPolicyTextBlock_lbl_6219c3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AccruedLiabilitiesPolicyTextBlock_lbl_6219c3" xml:lang="en-US"> Accrued Liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StockSubscriptionPayablePolicyTextBlock" xlink:label="gthp_StockSubscriptionPayablePolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockSubscriptionPayablePolicyTextBlock" xlink:to="gthp_StockSubscriptionPayablePolicyTextBlock_lbl_1219e1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StockSubscriptionPayablePolicyTextBlock_lbl_1219e1" xml:lang="en-US"> Stock Subscription Payable </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RevenueRecognitionPolicyTextBlock" xlink:label="us-gaap_RevenueRecognitionPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RevenueRecognitionPolicyTextBlock" xlink:to="us-gaap_RevenueRecognitionPolicyTextBlock_lbl_6ad5b1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RevenueRecognitionPolicyTextBlock_lbl_6ad5b1" xml:lang="en-US"> Revenue Recognition </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SignificantCustomersPolicyTextBlock" xlink:label="gthp_SignificantCustomersPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SignificantCustomersPolicyTextBlock" xlink:to="gthp_SignificantCustomersPolicyTextBlock_lbl_32f676" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SignificantCustomersPolicyTextBlock_lbl_32f676" xml:lang="en-US"> Significant Customers </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:label="us-gaap_ResearchAndDevelopmentExpensePolicy"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:to="us-gaap_ResearchAndDevelopmentExpensePolicy_lbl_48e079" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ResearchAndDevelopmentExpensePolicy_lbl_48e079" xml:lang="en-US"> Research and Development </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="us-gaap_IncomeTaxPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeTaxPolicyTextBlock" xlink:to="us-gaap_IncomeTaxPolicyTextBlock_lbl_739988" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeTaxPolicyTextBlock_lbl_739988" xml:lang="en-US"> Income Taxes </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantsPolicyTextBlock" xlink:label="gthp_WarrantsPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantsPolicyTextBlock" xlink:to="gthp_WarrantsPolicyTextBlock_lbl_2f33ae" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantsPolicyTextBlock_lbl_2f33ae" xml:lang="en-US"> Warrants </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy" xlink:label="us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy" xlink:to="us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_lbl_bc35ca" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_lbl_bc35ca" xml:lang="en-US"> Stock Based Compensation </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativesPolicyTextBlock" xlink:label="us-gaap_DerivativesPolicyTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DerivativesPolicyTextBlock" xlink:to="us-gaap_DerivativesPolicyTextBlock_lbl_d04b5f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DerivativesPolicyTextBlock_lbl_d04b5f" xml:lang="en-US"> Derivatives </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:label="us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:to="us-gaap_ScheduleOfInventoryCurrentTableTextBlock_lbl_0ea58f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfInventoryCurrentTableTextBlock_lbl_0ea58f" xml:lang="en-US"> Inventory valuation </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PropertyPlantAndEquipmentTableTextBlock" xlink:label="gthp_PropertyPlantAndEquipmentTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PropertyPlantAndEquipmentTableTextBlock" xlink:to="gthp_PropertyPlantAndEquipmentTableTextBlock_lbl_c03da6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PropertyPlantAndEquipmentTableTextBlock_lbl_c03da6" xml:lang="en-US"> Property and equipment </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:to="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_lbl_d1ec0f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_lbl_d1ec0f" xml:lang="en-US"> Accrued liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:label="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:to="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_lbl_4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_lbl_4" xml:lang="en-US"> Schedule of Accrued Liabilities [Table Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:to="us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_lbl_fc00dd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_lbl_fc00dd" xml:lang="en-US"> Schedule of fair value for liabilities measured on a recurring basis </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SummaryOfChangesToLevelThreeInstruments" xlink:label="gthp_SummaryOfChangesToLevelThreeInstruments"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SummaryOfChangesToLevelThreeInstruments" xlink:to="gthp_SummaryOfChangesToLevelThreeInstruments_lbl_ebe60d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SummaryOfChangesToLevelThreeInstruments_lbl_ebe60d" xml:lang="en-US"> Summary of changes to Level 3 instruments </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfStockByClassTextBlock" xlink:label="us-gaap_ScheduleOfStockByClassTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfStockByClassTextBlock" xlink:to="us-gaap_ScheduleOfStockByClassTextBlock_lbl_dfef3e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfStockByClassTextBlock_lbl_dfef3e" xml:lang="en-US"> Common stock issued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ScheduleOfCompanyOutstandingWarrantsToPurchaseCommonStockTableTextBlock" xlink:label="gthp_ScheduleOfCompanyOutstandingWarrantsToPurchaseCommonStockTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ScheduleOfCompanyOutstandingWarrantsToPurchaseCommonStockTableTextBlock" xlink:to="gthp_ScheduleOfCompanyOutstandingWarrantsToPurchaseCommonStockTableTextBlock_lbl_cd6820" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ScheduleOfCompanyOutstandingWarrantsToPurchaseCommonStockTableTextBlock_lbl_cd6820" xml:lang="en-US"> Company's outstanding warrants to purchase common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ScheduleOfFairValueWarrantsIssuedUnderBlackScholesOptionPricingModelTableTextblock" xlink:label="gthp_ScheduleOfFairValueWarrantsIssuedUnderBlackScholesOptionPricingModelTableTextblock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ScheduleOfFairValueWarrantsIssuedUnderBlackScholesOptionPricingModelTableTextblock" xlink:to="gthp_ScheduleOfFairValueWarrantsIssuedUnderBlackScholesOptionPricingModelTableTextblock_lbl_d89379" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ScheduleOfFairValueWarrantsIssuedUnderBlackScholesOptionPricingModelTableTextblock_lbl_d89379" xml:lang="en-US"> Schedule of fair value warrants issued under Black-Scholes Option Pricing model </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:label="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:to="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_lbl_ab14db" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_lbl_ab14db" xml:lang="en-US"> Stock option activity </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StockOptionsVestedUnvestedAndGrantedTableTextBlock" xlink:label="gthp_StockOptionsVestedUnvestedAndGrantedTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockOptionsVestedUnvestedAndGrantedTableTextBlock" xlink:to="gthp_StockOptionsVestedUnvestedAndGrantedTableTextBlock_lbl_d6b708" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StockOptionsVestedUnvestedAndGrantedTableTextBlock_lbl_d6b708" xml:lang="en-US"> Stock options vested, unvested and granted </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ScheduleOfStockOptionAwardsOnAStraightLineBasisTableTextBlock" xlink:label="gthp_ScheduleOfStockOptionAwardsOnAStraightLineBasisTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ScheduleOfStockOptionAwardsOnAStraightLineBasisTableTextBlock" xlink:to="gthp_ScheduleOfStockOptionAwardsOnAStraightLineBasisTableTextBlock_lbl_3d6f72" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ScheduleOfStockOptionAwardsOnAStraightLineBasisTableTextBlock_lbl_3d6f72" xml:lang="en-US"> Schedule of stock option awards on a straight-line basis </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_VestingAxis" xlink:label="us-gaap_VestingAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_VestingAxis" xlink:to="us-gaap_VestingAxis_lbl_d12495" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_VestingAxis_lbl_d12495" xml:lang="en-US"> Vesting [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationAwardTrancheOneMember" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationAwardTrancheOneMember" xlink:to="us-gaap_ShareBasedCompensationAwardTrancheOneMember_lbl_26a3c3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheOneMember_lbl_26a3c3" xml:lang="en-US"> Tranche One [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationAwardTrancheTwoMember" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheTwoMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationAwardTrancheTwoMember" xlink:to="us-gaap_ShareBasedCompensationAwardTrancheTwoMember_lbl_133faa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheTwoMember_lbl_133faa" xml:lang="en-US"> Tranche Two [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationAwardTrancheThreeMember" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheThreeMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationAwardTrancheThreeMember" xlink:to="us-gaap_ShareBasedCompensationAwardTrancheThreeMember_lbl_2a123e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheThreeMember_lbl_2a123e" xml:lang="en-US"> Tranche Three [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LeaseCostTableTextBlock" xlink:label="us-gaap_LeaseCostTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LeaseCostTableTextBlock" xlink:to="us-gaap_LeaseCostTableTextBlock_lbl_546825" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LeaseCostTableTextBlock_lbl_546825" xml:lang="en-US"> Operating lease right-of-use assets and lease liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock" xlink:label="us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock" xlink:to="us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock_lbl_47d5a0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock_lbl_47d5a0" xml:lang="en-US"> Maturities of operating lease liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ScheduleOfWeightedAverageRemainingLeaseTermAndDiscountRate" xlink:label="gthp_ScheduleOfWeightedAverageRemainingLeaseTermAndDiscountRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ScheduleOfWeightedAverageRemainingLeaseTermAndDiscountRate" xlink:to="gthp_ScheduleOfWeightedAverageRemainingLeaseTermAndDiscountRate_lbl_8fb6aa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ScheduleOfWeightedAverageRemainingLeaseTermAndDiscountRate_lbl_8fb6aa" xml:lang="en-US"> Weighted-average remaining lease term and discount rate </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisValuationTechniquesTextBlock" xlink:label="us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisValuationTechniquesTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisValuationTechniquesTextBlock" xlink:to="us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisValuationTechniquesTextBlock_lbl_888a2d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisValuationTechniquesTextBlock_lbl_888a2d" xml:lang="en-US"> Fair value of the warrants using the Black-Scholes option pricing model </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfShortTermDebtTextBlock" xlink:label="us-gaap_ScheduleOfShortTermDebtTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfShortTermDebtTextBlock" xlink:to="us-gaap_ScheduleOfShortTermDebtTextBlock_lbl_5d257a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfShortTermDebtTextBlock_lbl_5d257a" xml:lang="en-US"> Short-term notes payable, including related parties </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ScheduledOfUnamortizedDebtIssuanceCostsTableTextBlock" xlink:label="gthp_ScheduledOfUnamortizedDebtIssuanceCostsTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ScheduledOfUnamortizedDebtIssuanceCostsTableTextBlock" xlink:to="gthp_ScheduledOfUnamortizedDebtIssuanceCostsTableTextBlock_lbl_ba1ca0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ScheduledOfUnamortizedDebtIssuanceCostsTableTextBlock_lbl_ba1ca0" xml:lang="en-US"> Scheduled of unamortized debt issuance costs </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock" xlink:to="us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock_lbl_885071" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock_lbl_885071" xml:lang="en-US"> Long-term debt, related parties </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock" xlink:label="us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock" xlink:to="us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfRelatedPartyTransactionsTableTextBlock_lbl_2" xml:lang="en-US"> Schedule of Related Party Transactions [Table Text Block] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock" xlink:label="us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock" xlink:to="us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_lbl_5e51f1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_lbl_5e51f1" xml:lang="en-US"> Long-term debt, related parties debt obligations </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:to="us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_lbl_4dfd84" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_lbl_4dfd84" xml:lang="en-US"> Earnings per share </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RetainedEarningAccumulatedDeficit" xlink:to="gthp_RetainedEarningAccumulatedDeficit_lbl_b79688" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_RetainedEarningAccumulatedDeficit_lbl_b79688" xml:lang="en-US"> Accumulated deficit </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RetainedEarningAccumulatedDeficit" xlink:label="gthp_RetainedEarningAccumulatedDeficit"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RetainedEarningAccumulatedDeficit" xlink:to="gthp_RetainedEarningAccumulatedDeficit_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RetainedEarningAccumulatedDeficit_lbl_2" xml:lang="en-US"> [Accumulated deficit] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreconfirmationsStockholdersEquity" xlink:label="gthp_PreconfirmationsStockholdersEquity"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreconfirmationsStockholdersEquity" xlink:to="gthp_PreconfirmationsStockholdersEquity_lbl_f47dc4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreconfirmationsStockholdersEquity_lbl_f47dc4" xml:lang="en-US"> Total stockholders' deficits </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WorkingCapital" xlink:label="gthp_WorkingCapital"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WorkingCapital" xlink:to="gthp_WorkingCapital_lbl_9b3b04" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WorkingCapital_lbl_9b3b04" xml:lang="en-US"> Working capital </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NetLossPreferredDividend" xlink:label="gthp_NetLossPreferredDividend"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NetLossPreferredDividend" xlink:to="gthp_NetLossPreferredDividend_lbl_362e6f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NetLossPreferredDividend_lbl_362e6f" xml:lang="en-US"> Net loss including preferred dividend </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromSaleOfTrustAssetsToPayExpenses" xlink:label="us-gaap_ProceedsFromSaleOfTrustAssetsToPayExpenses"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromSaleOfTrustAssetsToPayExpenses" xlink:to="us-gaap_ProceedsFromSaleOfTrustAssetsToPayExpenses_lbl_f2092d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromSaleOfTrustAssetsToPayExpenses_lbl_f2092d" xml:lang="en-US"> Proceeds from sale of common stock and warrants (net of expenses) </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants" xlink:to="us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants_lbl_2ea1ea" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants_lbl_2ea1ea" xml:lang="en-US"> Proceeds from warrant exercises </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants" xlink:label="us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants" xlink:to="us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants_lbl_7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromIssuanceOfPreferredStockPreferenceStockAndWarrants_lbl_7" xml:lang="en-US"> [Proceeds from Issuance of Preferred Stock, Preference Stock, and Warrants] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InventoryRawMaterials" xlink:label="us-gaap_InventoryRawMaterials"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryRawMaterials" xlink:to="us-gaap_InventoryRawMaterials_lbl_567e4f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InventoryRawMaterials_lbl_567e4f" xml:lang="en-US"> Raw materials </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InventoryWorkInProcess" xlink:label="us-gaap_InventoryWorkInProcess"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryWorkInProcess" xlink:to="us-gaap_InventoryWorkInProcess_lbl_792309" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InventoryWorkInProcess_lbl_792309" xml:lang="en-US"> Work in process </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InventoryFinishedGoods" xlink:label="us-gaap_InventoryFinishedGoods"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryFinishedGoods" xlink:to="us-gaap_InventoryFinishedGoods_lbl_885d59" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InventoryFinishedGoods_lbl_885d59" xml:lang="en-US"> Finished goods </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryValuationReserves" xlink:to="us-gaap_InventoryValuationReserves_lbl_ec2265" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_InventoryValuationReserves_lbl_ec2265" xml:lang="en-US"> Inventory reserve </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InventoryValuationReserves" xlink:label="us-gaap_InventoryValuationReserves"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryValuationReserves" xlink:to="us-gaap_InventoryValuationReserves_lbl_5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InventoryValuationReserves_lbl_5" xml:lang="en-US"> [Inventory Valuation Reserves] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InventoryNet" xlink:to="us-gaap_InventoryNet_lbl_d9a27c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_InventoryNet_lbl_d9a27c" xml:lang="en-US"> Total </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_MajorPropertyClassAxis" xlink:label="us-gaap_MajorPropertyClassAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_MajorPropertyClassAxis" xlink:to="us-gaap_MajorPropertyClassAxis_lbl_c5eb1d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_MajorPropertyClassAxis_lbl_c5eb1d" xml:lang="en-US"> Major Property Class Axis </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:label="us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:to="us-gaap_PropertyPlantAndEquipmentByTypeAxis_lbl_9e025b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PropertyPlantAndEquipmentByTypeAxis_lbl_9e025b" xml:lang="en-US"> Property Plant And Equipment By Type Axis </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_EquipmentOneMember" xlink:label="gthp_EquipmentOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_EquipmentOneMember" xlink:to="gthp_EquipmentOneMember_lbl_ceebcb" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_EquipmentOneMember_lbl_ceebcb" xml:lang="en-US"> Equipment </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SoftwareLicenseArrangementOneMember" xlink:label="gthp_SoftwareLicenseArrangementOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SoftwareLicenseArrangementOneMember" xlink:to="gthp_SoftwareLicenseArrangementOneMember_lbl_3149d6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SoftwareLicenseArrangementOneMember_lbl_3149d6" xml:lang="en-US"> Software </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FurnitureAndFixturesMember" xlink:label="us-gaap_FurnitureAndFixturesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FurnitureAndFixturesMember" xlink:to="us-gaap_FurnitureAndFixturesMember_lbl_29e962" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FurnitureAndFixturesMember_lbl_29e962" xml:lang="en-US"> Furniture and Fixtures </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LeaseholdImprovementsOneMember" xlink:label="gthp_LeaseholdImprovementsOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LeaseholdImprovementsOneMember" xlink:to="gthp_LeaseholdImprovementsOneMember_lbl_7f9db2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LeaseholdImprovementsOneMember_lbl_7f9db2" xml:lang="en-US"> Leasehold Improvement </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:to="us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_lbl_1000d1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_lbl_1000d1" xml:lang="en-US"> Less accumulated depreciation and amortization </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:to="us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_lbl_2" xml:lang="en-US"> [Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PropertyPlantAndEquipmentNet" xlink:to="us-gaap_PropertyPlantAndEquipmentNet_lbl_c6405a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_lbl_c6405a" xml:lang="en-US"> Property and equipment, net </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="us-gaap_PropertyPlantAndEquipmentGross"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PropertyPlantAndEquipmentGross" xlink:to="us-gaap_PropertyPlantAndEquipmentGross_lbl_a28931" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PropertyPlantAndEquipmentGross_lbl_a28931" xml:lang="en-US"> Property and equipment, gross </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedBonusesCurrentAndNoncurrent" xlink:label="us-gaap_AccruedBonusesCurrentAndNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedBonusesCurrentAndNoncurrent" xlink:to="us-gaap_AccruedBonusesCurrentAndNoncurrent_lbl_b0ed36" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedBonusesCurrentAndNoncurrent_lbl_b0ed36" xml:lang="en-US"> Compensation </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedProfessionalFeesCurrentAndNoncurrent" xlink:label="us-gaap_AccruedProfessionalFeesCurrentAndNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedProfessionalFeesCurrentAndNoncurrent" xlink:to="us-gaap_AccruedProfessionalFeesCurrentAndNoncurrent_lbl_0a652a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedProfessionalFeesCurrentAndNoncurrent_lbl_0a652a" xml:lang="en-US"> Professional fees </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccruedStockSubscriptionPayable" xlink:to="gthp_AccruedStockSubscriptionPayable_lbl_610561" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_AccruedStockSubscriptionPayable_lbl_610561" xml:lang="en-US"> Stock Subscription Payable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AccruedStockSubscriptionPayable" xlink:label="gthp_AccruedStockSubscriptionPayable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccruedStockSubscriptionPayable" xlink:to="gthp_AccruedStockSubscriptionPayable_lbl_4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AccruedStockSubscriptionPayable_lbl_4" xml:lang="en-US"> [Stock Subscription Payable] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestPayableCurrent" xlink:label="us-gaap_InterestPayableCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InterestPayableCurrent" xlink:to="us-gaap_InterestPayableCurrent_lbl_32d0ba" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InterestPayableCurrent_lbl_32d0ba" xml:lang="en-US"> Interest </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedVacationCurrentAndNoncurrent" xlink:label="us-gaap_AccruedVacationCurrentAndNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedVacationCurrentAndNoncurrent" xlink:to="us-gaap_AccruedVacationCurrentAndNoncurrent_lbl_e6be76" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedVacationCurrentAndNoncurrent_lbl_e6be76" xml:lang="en-US"> Vacation </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DividendsPayableCurrent" xlink:label="us-gaap_DividendsPayableCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DividendsPayableCurrent" xlink:to="us-gaap_DividendsPayableCurrent_lbl_a734bc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DividendsPayableCurrent_lbl_a734bc" xml:lang="en-US"> Preferred dividends </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAccruedLiabilitiesCurrentAndNoncurrent" xlink:label="us-gaap_OtherAccruedLiabilitiesCurrentAndNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OtherAccruedLiabilitiesCurrentAndNoncurrent" xlink:to="us-gaap_OtherAccruedLiabilitiesCurrentAndNoncurrent_lbl_eae804" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OtherAccruedLiabilitiesCurrentAndNoncurrent_lbl_eae804" xml:lang="en-US"> Other accrued expenses </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedLiabilitiesCurrentAndNoncurrent" xlink:to="us-gaap_AccruedLiabilitiesCurrentAndNoncurrent_lbl_e3a504" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_AccruedLiabilitiesCurrentAndNoncurrent_lbl_e3a504" xml:lang="en-US"> Total </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedLiabilitiesCurrentAndNoncurrent" xlink:label="us-gaap_AccruedLiabilitiesCurrentAndNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedLiabilitiesCurrentAndNoncurrent" xlink:to="us-gaap_AccruedLiabilitiesCurrentAndNoncurrent_lbl_9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedLiabilitiesCurrentAndNoncurrent_lbl_9" xml:lang="en-US"> [Accrued Liabilities] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfWarrantOrRightAxis" xlink:label="us-gaap_ClassOfWarrantOrRightAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ClassOfWarrantOrRightAxis" xlink:to="us-gaap_ClassOfWarrantOrRightAxis_lbl_efb381" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ClassOfWarrantOrRightAxis_lbl_efb381" xml:lang="en-US"> Class of Warrant or Right [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StockIssuedToConsultantsMember" xlink:label="gthp_StockIssuedToConsultantsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockIssuedToConsultantsMember" xlink:to="gthp_StockIssuedToConsultantsMember_lbl_4ee689" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StockIssuedToConsultantsMember_lbl_4ee689" xml:lang="en-US"> Stock Issued To Consultants </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantsIssuedToConsultantsAndExecutivesMember" xlink:label="gthp_WarrantsIssuedToConsultantsAndExecutivesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantsIssuedToConsultantsAndExecutivesMember" xlink:to="gthp_WarrantsIssuedToConsultantsAndExecutivesMember_lbl_d2b0f5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantsIssuedToConsultantsAndExecutivesMember_lbl_d2b0f5" xml:lang="en-US"> Warrants Issued To Consultants and Executives </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsReceivableGrossCurrent" xlink:label="us-gaap_AccountsReceivableGrossCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccountsReceivableGrossCurrent" xlink:to="us-gaap_AccountsReceivableGrossCurrent_lbl_c41110" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccountsReceivableGrossCurrent_lbl_c41110" xml:lang="en-US"> Accounts receivable outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DepreciationNonproduction" xlink:label="us-gaap_DepreciationNonproduction"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DepreciationNonproduction" xlink:to="us-gaap_DepreciationNonproduction_lbl_396fc7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DepreciationNonproduction_lbl_396fc7" xml:lang="en-US"> Depreciation expense </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccretionExpense" xlink:label="us-gaap_AccretionExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccretionExpense" xlink:to="us-gaap_AccretionExpense_lbl_485ae1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccretionExpense_lbl_485ae1" xml:lang="en-US"> Accrued expense </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AllowanceForDoubtfulAccountsReceivable" xlink:to="us-gaap_AllowanceForDoubtfulAccountsReceivable_lbl_43c4d4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_AllowanceForDoubtfulAccountsReceivable_lbl_43c4d4" xml:lang="en-US"> Accounts receivable, net of allowance </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable" xlink:label="us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AllowanceForDoubtfulAccountsReceivable" xlink:to="us-gaap_AllowanceForDoubtfulAccountsReceivable_lbl_5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AllowanceForDoubtfulAccountsReceivable_lbl_5" xml:lang="en-US"> [Accounts Receivable, Allowance for Credit Loss] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredRevenue" xlink:to="us-gaap_DeferredRevenue_lbl_87bc5c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_DeferredRevenue_lbl_87bc5c" xml:lang="en-US"> Deferred revenue </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredRevenue" xlink:label="us-gaap_DeferredRevenue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredRevenue" xlink:to="us-gaap_DeferredRevenue_lbl_6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredRevenue_lbl_6" xml:lang="en-US"> [Deferred Revenue] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RevenueRemainingPerformanceObligation" xlink:label="us-gaap_RevenueRemainingPerformanceObligation"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RevenueRemainingPerformanceObligation" xlink:to="us-gaap_RevenueRemainingPerformanceObligation_lbl_77f1b5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RevenueRemainingPerformanceObligation_lbl_77f1b5" xml:lang="en-US"> Remaining balance </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLossCarryforwards" xlink:label="us-gaap_OperatingLossCarryforwards"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLossCarryforwards" xlink:to="us-gaap_OperatingLossCarryforwards_lbl_3a19cd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLossCarryforwards_lbl_3a19cd" xml:lang="en-US"> Net operating loss carry forward </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PremiumsPercentageAssumedToNet" xlink:label="us-gaap_PremiumsPercentageAssumedToNet"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PremiumsPercentageAssumedToNet" xlink:to="us-gaap_PremiumsPercentageAssumedToNet_lbl_e5521c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PremiumsPercentageAssumedToNet_lbl_e5521c" xml:lang="en-US"> Percentage amount of tax benefit </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExcessedAmountOfInsuredLimitations" xlink:label="gthp_ExcessedAmountOfInsuredLimitations"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExcessedAmountOfInsuredLimitations" xlink:to="gthp_ExcessedAmountOfInsuredLimitations_lbl_7d019e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExcessedAmountOfInsuredLimitations_lbl_7d019e" xml:lang="en-US"> Excess of insured limitations </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockOptionPlanExpense" xlink:label="us-gaap_StockOptionPlanExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockOptionPlanExpense" xlink:to="us-gaap_StockOptionPlanExpense_lbl_d87977" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockOptionPlanExpense_lbl_d87977" xml:lang="en-US"> Recognized expense related to stock options </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:to="us-gaap_FairValueByFairValueHierarchyLevelAxis_lbl_78e73a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueByFairValueHierarchyLevelAxis_lbl_78e73a" xml:lang="en-US"> Fair Value Hierarchy and NAV [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AuctusLoanMember" xlink:label="gthp_AuctusLoanMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AuctusLoanMember" xlink:to="gthp_AuctusLoanMember_lbl_572bf4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AuctusLoanMember_lbl_572bf4" xml:lang="en-US"> Auctus Loan </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="us-gaap_FairValueInputsLevel1Member"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueInputsLevel1Member" xlink:to="us-gaap_FairValueInputsLevel1Member_lbl_c1afb5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueInputsLevel1Member_lbl_c1afb5" xml:lang="en-US"> Level 1 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="us-gaap_FairValueInputsLevel2Member"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueInputsLevel2Member" xlink:to="us-gaap_FairValueInputsLevel2Member_lbl_c2a0f4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueInputsLevel2Member_lbl_c2a0f4" xml:lang="en-US"> Level 2 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="us-gaap_FairValueInputsLevel3Member"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueInputsLevel3Member" xlink:to="us-gaap_FairValueInputsLevel3Member_lbl_9642a5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueInputsLevel3Member_lbl_9642a5" xml:lang="en-US"> Level 3 </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DerivativeLiabilities" xlink:to="us-gaap_DerivativeLiabilities_lbl_50584f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_DerivativeLiabilities_lbl_50584f" xml:lang="en-US"> Derivative liability </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DerivativeLiabilities" xlink:label="us-gaap_DerivativeLiabilities"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DerivativeLiabilities" xlink:to="us-gaap_DerivativeLiabilities_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DerivativeLiabilities_lbl_2" xml:lang="en-US"> [Derivative Liability] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DerivativesMember" xlink:label="gthp_DerivativesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DerivativesMember" xlink:to="gthp_DerivativesMember_lbl_7c5146" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DerivativesMember_lbl_7c5146" xml:lang="en-US"> Derivative </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueInputsLevel3Member" xlink:to="us-gaap_FairValueInputsLevel3Member_lbl_1915f7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_FairValueInputsLevel3Member_lbl_1915f7" xml:lang="en-US"> Level 3 </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DerivativeLiabilities" xlink:to="us-gaap_DerivativeLiabilities_lbl_52d630" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_DerivativeLiabilities_lbl_52d630" xml:lang="en-US"> Beginning Balance </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FairValueAdjustmentOfWarrants" xlink:label="us-gaap_FairValueAdjustmentOfWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FairValueAdjustmentOfWarrants" xlink:to="us-gaap_FairValueAdjustmentOfWarrants_lbl_e6a501" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FairValueAdjustmentOfWarrants_lbl_e6a501" xml:lang="en-US"> Change in fair value during the year </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DerivativeLiabilities" xlink:to="us-gaap_DerivativeLiabilities_lbl_2ee729" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_DerivativeLiabilities_lbl_2ee729" xml:lang="en-US"> Ending Balance </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DerivativeLiabilityBifurcatedConversionOptionActusLoanAmount" xlink:label="gthp_DerivativeLiabilityBifurcatedConversionOptionActusLoanAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DerivativeLiabilityBifurcatedConversionOptionActusLoanAmount" xlink:to="gthp_DerivativeLiabilityBifurcatedConversionOptionActusLoanAmount_lbl_49ae3e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DerivativeLiabilityBifurcatedConversionOptionActusLoanAmount_lbl_49ae3e" xml:lang="en-US"> Derivative liability/bifurcated conversion option auctus loan amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonstockwarrantsexercisedMember" xlink:label="gthp_CommonstockwarrantsexercisedMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonstockwarrantsexercisedMember" xlink:to="gthp_CommonstockwarrantsexercisedMember_lbl_56cb71" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonstockwarrantsexercisedMember_lbl_56cb71" xml:lang="en-US"> Common stock warrants exercised [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsMember" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsMember" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsMember_lbl_c89a74" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesDPreferredDividendsMember_lbl_c89a74" xml:lang="en-US"> Issuance of common stock for payment of Series D preferred dividends [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsMember" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsMember" xlink:to="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsMember_lbl_710c1f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentOfSeriesEPreferredDividendsMember_lbl_710c1f" xml:lang="en-US"> Issuance of common stock for payment of Series E preferred dividends [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceofcommonstockforpaymentofSeriesFpreferreddividendsMember" xlink:label="gthp_IssuanceofcommonstockforpaymentofSeriesFpreferreddividendsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceofcommonstockforpaymentofSeriesFpreferreddividendsMember" xlink:to="gthp_IssuanceofcommonstockforpaymentofSeriesFpreferreddividendsMember_lbl_35b193" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceofcommonstockforpaymentofSeriesFpreferreddividendsMember_lbl_35b193" xml:lang="en-US"> Issuance of common stock for payment of Series F preferred dividends [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceofcommonstockforpaymentofSeriesFTwopreferreddividendsMember" xlink:label="gthp_IssuanceofcommonstockforpaymentofSeriesFTwopreferreddividendsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceofcommonstockforpaymentofSeriesFTwopreferreddividendsMember" xlink:to="gthp_IssuanceofcommonstockforpaymentofSeriesFTwopreferreddividendsMember_lbl_73407c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceofcommonstockforpaymentofSeriesFTwopreferreddividendsMember_lbl_73407c" xml:lang="en-US"> Issuance of common stock for payment of Series F-2 preferred dividends [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceofcommonstockforpaymentofinterestMember" xlink:label="gthp_IssuanceofcommonstockforpaymentofinterestMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceofcommonstockforpaymentofinterestMember" xlink:to="gthp_IssuanceofcommonstockforpaymentofinterestMember_lbl_23d5cb" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceofcommonstockforpaymentofinterestMember_lbl_23d5cb" xml:lang="en-US"> Issuance of common stock for payment of interest [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceofcommonstocktoconsultantsMember" xlink:label="gthp_IssuanceofcommonstocktoconsultantsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceofcommonstocktoconsultantsMember" xlink:to="gthp_IssuanceofcommonstocktoconsultantsMember_lbl_9d0c3f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceofcommonstocktoconsultantsMember_lbl_9d0c3f" xml:lang="en-US"> Issuance of common stock to consultants [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionofSeriesEpreferredstocktocommonstockMember" xlink:label="gthp_ConversionofSeriesEpreferredstocktocommonstockMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionofSeriesEpreferredstocktocommonstockMember" xlink:to="gthp_ConversionofSeriesEpreferredstocktocommonstockMember_lbl_2406e3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionofSeriesEpreferredstocktocommonstockMember_lbl_2406e3" xml:lang="en-US"> Conversion of Series E preferred stock to common stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionofSeriesFpreferredstocktocommonstockMember" xlink:label="gthp_ConversionofSeriesFpreferredstocktocommonstockMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionofSeriesFpreferredstocktocommonstockMember" xlink:to="gthp_ConversionofSeriesFpreferredstocktocommonstockMember_lbl_95aa33" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionofSeriesFpreferredstocktocommonstockMember_lbl_95aa33" xml:lang="en-US"> Conversion of Series F preferred stock to common stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionofSeriesFTwopreferredstocktocommonstockMember" xlink:label="gthp_ConversionofSeriesFTwopreferredstocktocommonstockMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionofSeriesFTwopreferredstocktocommonstockMember" xlink:to="gthp_ConversionofSeriesFTwopreferredstocktocommonstockMember_lbl_24ecf4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionofSeriesFTwopreferredstocktocommonstockMember_lbl_24ecf4" xml:lang="en-US"> Conversion of Series F-2 preferred stock to common stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StockIssuedMember" xlink:label="gthp_StockIssuedMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockIssuedMember" xlink:to="gthp_StockIssuedMember_lbl_9cd9a0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StockIssuedMember_lbl_9cd9a0" xml:lang="en-US"> Stock Issued [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockDividendsShares" xlink:label="us-gaap_CommonStockDividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockDividendsShares" xlink:to="us-gaap_CommonStockDividendsShares_lbl_b465f7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockDividendsShares_lbl_b465f7" xml:lang="en-US"> Issuances of common stock </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesOutstanding" xlink:to="us-gaap_SharesOutstanding_lbl_6ccdee" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_SharesOutstanding_lbl_6ccdee" xml:lang="en-US"> Share outstanding, end </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharesOutstanding" xlink:label="us-gaap_SharesOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesOutstanding" xlink:to="us-gaap_SharesOutstanding_lbl_3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharesOutstanding_lbl_3" xml:lang="en-US"> [Shares, Outstanding] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesOutstanding" xlink:to="us-gaap_SharesOutstanding_lbl_1673ee" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_SharesOutstanding_lbl_1673ee" xml:lang="en-US"> Share outstanding, begin </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConversionOfStockSharesIssued1" xlink:label="us-gaap_ConversionOfStockSharesIssued1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConversionOfStockSharesIssued1" xlink:to="us-gaap_ConversionOfStockSharesIssued1_lbl_08b12b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConversionOfStockSharesIssued1_lbl_08b12b" xml:lang="en-US"> Conversion of common stock </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_lbl_f85ff2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_lbl_f85ff2" xml:lang="en-US"> Warrants outstanding, beginning </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_lbl_2" xml:lang="en-US"> [Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsGranted" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsGranted"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsGranted" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsGranted_lbl_fe6bd5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsGranted_lbl_fe6bd5" xml:lang="en-US"> Warrants issued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsWarrantsExchanged" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsWarrantsExchanged"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsWarrantsExchanged" xlink:to="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsWarrantsExchanged_lbl_73bfb9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsWarrantsExchanged_lbl_73bfb9" xml:lang="en-US"> Warrants exchanged </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations_lbl_1b7221" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations_lbl_1b7221" xml:lang="en-US"> Warrants cancelled/expired </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations_lbl_5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsForfeituresAndExpirations_lbl_5" xml:lang="en-US"> [Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Forfeitures and Expirations] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised_lbl_9f46b5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised_lbl_9f46b5" xml:lang="en-US"> Warrants exercised </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised_lbl_6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsExercised_lbl_6" xml:lang="en-US"> [Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Exercised] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_lbl_95e4a7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_lbl_95e4a7" xml:lang="en-US"> Warrants outstanding, end </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl_7218c8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl_7218c8" xml:lang="en-US"> Weighted Average Exercise Price Per Share, beginning </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl_8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl_8" xml:lang="en-US"> [Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePriceWarrantIssued" xlink:label="gthp_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePriceWarrantIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePriceWarrantIssued" xlink:to="gthp_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePriceWarrantIssued_lbl_df8378" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePriceWarrantIssued_lbl_df8378" xml:lang="en-US"> Weighted Average Exercise Price Per Share, Warrants issued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePriceExpired" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePriceExpired"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePriceExpired" xlink:to="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePriceExpired_lbl_a4f6ab" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePriceExpired_lbl_a4f6ab" xml:lang="en-US"> Weighted Average Exercise Price Per Share, Warrants cancelled/expired </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForExchangeInPeriodWeightedAverageExercisePrice" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForExchangeInPeriodWeightedAverageExercisePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForExchangeInPeriodWeightedAverageExercisePrice" xlink:to="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForExchangeInPeriodWeightedAverageExercisePrice_lbl_d6c50f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForExchangeInPeriodWeightedAverageExercisePrice_lbl_d6c50f" xml:lang="en-US"> Weighted Average Exercise Price Per Share, Warrants exchanged </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_lbl_91f2b1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_lbl_91f2b1" xml:lang="en-US"> Weighted Average Exercise Price Per Share, Warrants exercised </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl_de1c44" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_lbl_de1c44" xml:lang="en-US"> Weighted Average Exercise Price Per Share, ending </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_lbl_fc7e0f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_lbl_fc7e0f" xml:lang="en-US"> Expected term </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_lbl_61470f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_lbl_61470f" xml:lang="en-US"> Volatility </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_lbl_b26fcf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_lbl_b26fcf" xml:lang="en-US"> Risk-free interest rate </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_lbl_90dfec" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_lbl_90dfec" xml:lang="en-US"> Dividend yield </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PlanNameAxis" xlink:label="us-gaap_PlanNameAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PlanNameAxis" xlink:to="us-gaap_PlanNameAxis_lbl_46f5f9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PlanNameAxis_lbl_46f5f9" xml:lang="en-US"> Plan Name Axis </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:to="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_lbl_b11ca2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_lbl_b11ca2" xml:lang="en-US"> Related Party [Axis] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesCPreferredSharesMember" xlink:to="gthp_SeriesCPreferredSharesMember_lbl_17b55b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_SeriesCPreferredSharesMember_lbl_17b55b" xml:lang="en-US"> Series C Convertible Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesDPreferredSharesMember" xlink:label="gthp_SeriesDPreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesDPreferredSharesMember" xlink:to="gthp_SeriesDPreferredSharesMember_lbl_24e9d0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesDPreferredSharesMember_lbl_24e9d0" xml:lang="en-US"> Series D Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesFPreferredSharesMember" xlink:label="gthp_SeriesFPreferredSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesFPreferredSharesMember" xlink:to="gthp_SeriesFPreferredSharesMember_lbl_fb3008" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesFPreferredSharesMember_lbl_fb3008" xml:lang="en-US"> Series F Preferred Shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesEConvertiblePreferredStockMember" xlink:label="gthp_SeriesEConvertiblePreferredStockMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesEConvertiblePreferredStockMember" xlink:to="gthp_SeriesEConvertiblePreferredStockMember_lbl_1092e7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesEConvertiblePreferredStockMember_lbl_1092e7" xml:lang="en-US"> Series E Convertible Preferred Stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSharesMember" xlink:label="gthp_PreferredStockSharesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSharesMember" xlink:to="gthp_PreferredStockSharesMember_lbl_560a43" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSharesMember_lbl_560a43" xml:lang="en-US"> Preferred Stock Shares [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesCConvertiblePreferredStockMember" xlink:label="gthp_SeriesCConvertiblePreferredStockMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesCConvertiblePreferredStockMember" xlink:to="gthp_SeriesCConvertiblePreferredStockMember_lbl_94fc1a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesCConvertiblePreferredStockMember_lbl_94fc1a" xml:lang="en-US"> Series C Convertible Preferred Stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantsMember" xlink:label="gthp_WarrantsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantsMember" xlink:to="gthp_WarrantsMember_lbl_f91857" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantsMember_lbl_f91857" xml:lang="en-US"> Warrants [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantsExchangesTwoThousandTwentyOneMember" xlink:label="gthp_WarrantsExchangesTwoThousandTwentyOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantsExchangesTwoThousandTwentyOneMember" xlink:to="gthp_WarrantsExchangesTwoThousandTwentyOneMember_lbl_86098b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantsExchangesTwoThousandTwentyOneMember_lbl_86098b" xml:lang="en-US"> Warrants Exchanges - 2021 </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RichardBlumbergMember" xlink:label="gthp_RichardBlumbergMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RichardBlumbergMember" xlink:to="gthp_RichardBlumbergMember_lbl_4a4f88" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RichardBlumbergMember_lbl_4a4f88" xml:lang="en-US"> Richard Blumberg [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantsOneMember" xlink:label="gthp_WarrantsOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantsOneMember" xlink:to="gthp_WarrantsOneMember_lbl_6b8861" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantsOneMember_lbl_6b8861" xml:lang="en-US"> Warrants One [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MarkFaupelMember" xlink:label="gthp_MarkFaupelMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MarkFaupelMember" xlink:to="gthp_MarkFaupelMember_lbl_fb7983" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MarkFaupelMember_lbl_fb7983" xml:lang="en-US"> Mark Faupel [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_FoodAndDrugAdministrationMember" xlink:label="gthp_FoodAndDrugAdministrationMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FoodAndDrugAdministrationMember" xlink:to="gthp_FoodAndDrugAdministrationMember_lbl_8266f1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_FoodAndDrugAdministrationMember_lbl_8266f1" xml:lang="en-US"> Food and Drug Administration [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ChineseNationalMedicalProductsAdministrationMember" xlink:label="gthp_ChineseNationalMedicalProductsAdministrationMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ChineseNationalMedicalProductsAdministrationMember" xlink:to="gthp_ChineseNationalMedicalProductsAdministrationMember_lbl_720ecc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ChineseNationalMedicalProductsAdministrationMember_lbl_720ecc" xml:lang="en-US"> Chinese National Medical Products Administration [Member] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockSharesAuthorized" xlink:to="us-gaap_CommonStockSharesAuthorized_lbl_e7590a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_CommonStockSharesAuthorized_lbl_e7590a" xml:lang="en-US"> Common stock, shares authorized </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SharesOfCommonStockIssued" xlink:label="gthp_SharesOfCommonStockIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SharesOfCommonStockIssued" xlink:to="gthp_SharesOfCommonStockIssued_lbl_f56779" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SharesOfCommonStockIssued_lbl_f56779" xml:lang="en-US"> Shares of common stock issued </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockDividendsShares" xlink:to="us-gaap_CommonStockDividendsShares_lbl_28413c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_CommonStockDividendsShares_lbl_28413c" xml:lang="en-US"> Issuances of common stock </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="us-gaap_AllocatedShareBasedCompensationExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AllocatedShareBasedCompensationExpense" xlink:to="us-gaap_AllocatedShareBasedCompensationExpense_lbl_e6c2e1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AllocatedShareBasedCompensationExpense_lbl_e6c2e1" xml:lang="en-US"> Stock-based compensation expense </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonUnitOutstanding" xlink:label="us-gaap_CommonUnitOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonUnitOutstanding" xlink:to="us-gaap_CommonUnitOutstanding_lbl_820028" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonUnitOutstanding_lbl_820028" xml:lang="en-US"> Common stock shares outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockWarrants" xlink:label="gthp_CommonStockWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockWarrants" xlink:to="gthp_CommonStockWarrants_lbl_7e2eb9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockWarrants_lbl_7e2eb9" xml:lang="en-US"> Common stock warrants </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockParOrStatedValuePerShare" xlink:to="us-gaap_CommonStockParOrStatedValuePerShare_lbl_1852b0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_CommonStockParOrStatedValuePerShare_lbl_1852b0" xml:lang="en-US"> Common stock, par value </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConversionOfStockSharesIssued1" xlink:to="us-gaap_ConversionOfStockSharesIssued1_lbl_3898d3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ConversionOfStockSharesIssued1_lbl_3898d3" xml:lang="en-US"> Preferred stock shares converts into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OptionIndexedToIssuersEquityStrikePrice1" xlink:label="us-gaap_OptionIndexedToIssuersEquityStrikePrice1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OptionIndexedToIssuersEquityStrikePrice1" xlink:to="us-gaap_OptionIndexedToIssuersEquityStrikePrice1_lbl_7e0300" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OptionIndexedToIssuersEquityStrikePrice1_lbl_7e0300" xml:lang="en-US"> Conversion price per share </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSharesDesignated" xlink:label="gthp_PreferredStockSharesDesignated"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSharesDesignated" xlink:to="gthp_PreferredStockSharesDesignated_lbl_f115b2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSharesDesignated_lbl_f115b2" xml:lang="en-US"> Preferred stock shares designated </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CapitalUnitsOutstanding" xlink:label="us-gaap_CapitalUnitsOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CapitalUnitsOutstanding" xlink:to="us-gaap_CapitalUnitsOutstanding_lbl_6920e9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CapitalUnitsOutstanding_lbl_6920e9" xml:lang="en-US"> Dividing the stated value </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities" xlink:label="us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities" xlink:to="us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_lbl_fc1384" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_lbl_fc1384" xml:lang="en-US"> Total convertible of common stock shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CumulativeDividendAnnualRate" xlink:label="gthp_CumulativeDividendAnnualRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CumulativeDividendAnnualRate" xlink:to="gthp_CumulativeDividendAnnualRate_lbl_dcdc49" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CumulativeDividendAnnualRate_lbl_dcdc49" xml:lang="en-US"> Cumulative dividend annual rate </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_UnpaidAccruedDividends" xlink:label="gthp_UnpaidAccruedDividends"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_UnpaidAccruedDividends" xlink:to="gthp_UnpaidAccruedDividends_lbl_e36edf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_UnpaidAccruedDividends_lbl_e36edf" xml:lang="en-US"> Unpaid accrued dividends </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MakeWholePaymentForConvertedShare" xlink:label="gthp_MakeWholePaymentForConvertedShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MakeWholePaymentForConvertedShare" xlink:to="gthp_MakeWholePaymentForConvertedShare_lbl_7bf062" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MakeWholePaymentForConvertedShare_lbl_7bf062" xml:lang="en-US"> Make-whole payment for converted share </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockLiquidationPreferenceValue" xlink:label="us-gaap_PreferredStockLiquidationPreferenceValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockLiquidationPreferenceValue" xlink:to="us-gaap_PreferredStockLiquidationPreferenceValue_lbl_d85ad2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockLiquidationPreferenceValue_lbl_d85ad2" xml:lang="en-US"> Liquidation preference </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockConvertibleSharesIssuable" xlink:label="us-gaap_PreferredStockConvertibleSharesIssuable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockConvertibleSharesIssuable" xlink:to="us-gaap_PreferredStockConvertibleSharesIssuable_lbl_328c09" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockConvertibleSharesIssuable_lbl_328c09" xml:lang="en-US"> Outstanding shares exchanged to Preferred stock </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonUnitIssued" xlink:label="us-gaap_CommonUnitIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonUnitIssued" xlink:to="us-gaap_CommonUnitIssued_lbl_d03fbd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonUnitIssued_lbl_d03fbd" xml:lang="en-US"> Company issued common stock </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockParOrStatedValuePerShare" xlink:to="us-gaap_PreferredStockParOrStatedValuePerShare_lbl_7a8fa5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_PreferredStockParOrStatedValuePerShare_lbl_7a8fa5" xml:lang="en-US"> Preferred stock, par value </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PercentageOfDividend" xlink:label="gthp_PercentageOfDividend"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PercentageOfDividend" xlink:to="gthp_PercentageOfDividend_lbl_b98b8b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PercentageOfDividend_lbl_b98b8b" xml:lang="en-US"> Percentage of dividend </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IncreasedBeneficialOwnershipPercentage" xlink:label="gthp_IncreasedBeneficialOwnershipPercentage"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IncreasedBeneficialOwnershipPercentage" xlink:to="gthp_IncreasedBeneficialOwnershipPercentage_lbl_f479ce" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IncreasedBeneficialOwnershipPercentage_lbl_f479ce" xml:lang="en-US"> Increased beneficial ownership percentage </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockPrimaryTradingSharesExceed" xlink:label="gthp_CommonStockPrimaryTradingSharesExceed"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockPrimaryTradingSharesExceed" xlink:to="gthp_CommonStockPrimaryTradingSharesExceed_lbl_fc1a72" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockPrimaryTradingSharesExceed_lbl_fc1a72" xml:lang="en-US"> Common Stock primary trading shares exceed </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExceedsPercentage" xlink:label="gthp_ExceedsPercentage"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExceedsPercentage" xlink:to="gthp_ExceedsPercentage_lbl_7b332c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExceedsPercentage_lbl_7b332c" xml:lang="en-US"> Exceeds percentage </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockShareOutstanding" xlink:to="gthp_PreferredStockShareOutstanding_lbl_c98545" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_PreferredStockShareOutstanding_lbl_c98545" xml:lang="en-US"> Preferred stock shares outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockShareOutstanding" xlink:label="gthp_PreferredStockShareOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockShareOutstanding" xlink:to="gthp_PreferredStockShareOutstanding_lbl_25" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockShareOutstanding_lbl_25" xml:lang="en-US"> [Preferred stock shares outstanding] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConversionBeneficialOwnershipLimitation" xlink:label="gthp_ConversionBeneficialOwnershipLimitation"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConversionBeneficialOwnershipLimitation" xlink:to="gthp_ConversionBeneficialOwnershipLimitation_lbl_ada7c3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConversionBeneficialOwnershipLimitation_lbl_ada7c3" xml:lang="en-US"> Conversion beneficial ownership limitation </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MaturityOfTimeDeposit" xlink:label="gthp_MaturityOfTimeDeposit"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MaturityOfTimeDeposit" xlink:to="gthp_MaturityOfTimeDeposit_lbl_38d6ec" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MaturityOfTimeDeposit_lbl_38d6ec" xml:lang="en-US"> Maturity period </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeriesF2PreferredStockDividendsShares" xlink:label="gthp_SeriesF2PreferredStockDividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeriesF2PreferredStockDividendsShares" xlink:to="gthp_SeriesF2PreferredStockDividendsShares_lbl_25e442" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeriesF2PreferredStockDividendsShares_lbl_25e442" xml:lang="en-US"> Series F-2 Preferred Stock dividends shares </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_TreasuryStockPreferredShares" xlink:label="us-gaap_TreasuryStockPreferredShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_TreasuryStockPreferredShares" xlink:to="us-gaap_TreasuryStockPreferredShares_lbl_f146e5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_TreasuryStockPreferredShares_lbl_f146e5" xml:lang="en-US"> Preferred stock shares received </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StatedValueOfPreferenceShare" xlink:label="gthp_StatedValueOfPreferenceShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StatedValueOfPreferenceShare" xlink:to="gthp_StatedValueOfPreferenceShare_lbl_7c8ae3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StatedValueOfPreferenceShare_lbl_7c8ae3" xml:lang="en-US"> Stated value of preference share </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StrikePriceOfWarrants" xlink:label="gthp_StrikePriceOfWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StrikePriceOfWarrants" xlink:to="gthp_StrikePriceOfWarrants_lbl_4d4d5f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StrikePriceOfWarrants_lbl_4d4d5f" xml:lang="en-US"> Strike price of warrants </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_VestedShsres" xlink:label="gthp_VestedShsres"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_VestedShsres" xlink:to="gthp_VestedShsres_lbl_e9d011" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_VestedShsres_lbl_e9d011" xml:lang="en-US"> Warrant vested shsres </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:to="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_lbl_349e8f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_lbl_349e8f" xml:lang="en-US"> Exercisable term </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtAverageAmountOutstanding" xlink:label="us-gaap_LongTermDebtAverageAmountOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtAverageAmountOutstanding" xlink:to="us-gaap_LongTermDebtAverageAmountOutstanding_lbl_fa4aa6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtAverageAmountOutstanding_lbl_fa4aa6" xml:lang="en-US"> Outstanding debt </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExchangeCommonStockWarrants" xlink:label="gthp_ExchangeCommonStockWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExchangeCommonStockWarrants" xlink:to="gthp_ExchangeCommonStockWarrants_lbl_0622c7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExchangeCommonStockWarrants_lbl_0622c7" xml:lang="en-US"> Exchange common stock warrants </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesIssued" xlink:to="us-gaap_PreferredStockSharesIssued_lbl_ab2936" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_PreferredStockSharesIssued_lbl_ab2936" xml:lang="en-US"> Preferred stock shares issued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSharesIssuedOne" xlink:label="gthp_PreferredStockSharesIssuedOne"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSharesIssuedOne" xlink:to="gthp_PreferredStockSharesIssuedOne_lbl_b7b61f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSharesIssuedOne_lbl_b7b61f" xml:lang="en-US"> Preferred stock shares issued one </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesOutstanding" xlink:to="us-gaap_PreferredStockSharesOutstanding_lbl_a6433f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_PreferredStockSharesOutstanding_lbl_a6433f" xml:lang="en-US"> Preferred stock shares outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockWarrantsStrikePricePerShare" xlink:label="gthp_CommonStockWarrantsStrikePricePerShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockWarrantsStrikePricePerShare" xlink:to="gthp_CommonStockWarrantsStrikePricePerShare_lbl_ddff5f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockWarrantsStrikePricePerShare_lbl_ddff5f" xml:lang="en-US"> Common stock warrants strike price per share </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockSharesSurrendered" xlink:label="gthp_PreferredStockSharesSurrendered"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockSharesSurrendered" xlink:to="gthp_PreferredStockSharesSurrendered_lbl_7e07d6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockSharesSurrendered_lbl_7e07d6" xml:lang="en-US"> Preferred stock shares surrendered </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExerciseOfWarrants" xlink:label="gthp_ExerciseOfWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExerciseOfWarrants" xlink:to="gthp_ExerciseOfWarrants_lbl_d8e9ae" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExerciseOfWarrants_lbl_d8e9ae" xml:lang="en-US"> Exercise of warrants, value </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExerciseOfWarrantsShares" xlink:label="gthp_ExerciseOfWarrantsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExerciseOfWarrantsShares" xlink:to="gthp_ExerciseOfWarrantsShares_lbl_088f5d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExerciseOfWarrantsShares_lbl_088f5d" xml:lang="en-US"> Exercise of warrants, shares </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Dividends" xlink:label="us-gaap_Dividends"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_Dividends" xlink:to="us-gaap_Dividends_lbl_bd3410" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_Dividends_lbl_bd3410" xml:lang="en-US"> Deemed dividend </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantIssued" xlink:label="gthp_WarrantIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantIssued" xlink:to="gthp_WarrantIssued_lbl_e3bbdd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantIssued_lbl_e3bbdd" xml:lang="en-US"> Number of warrant issued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockIssuedPublicStockShares" xlink:label="gthp_CommonStockIssuedPublicStockShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockIssuedPublicStockShares" xlink:to="gthp_CommonStockIssuedPublicStockShares_lbl_62a357" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockIssuedPublicStockShares_lbl_62a357" xml:lang="en-US"> Common stock, issued public shares </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockConvertedShare" xlink:label="gthp_PreferredStockConvertedShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockConvertedShare" xlink:to="gthp_PreferredStockConvertedShare_lbl_d87b78" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockConvertedShare_lbl_d87b78" xml:lang="en-US"> Preferred stock converted share </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesOutstanding" xlink:to="us-gaap_SharesOutstanding_lbl_a6ce97" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_SharesOutstanding_lbl_a6ce97" xml:lang="en-US"> Shares outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantExercisePricePerShare" xlink:label="gthp_WarrantExercisePricePerShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantExercisePricePerShare" xlink:to="gthp_WarrantExercisePricePerShare_lbl_9393cf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantExercisePricePerShare_lbl_9393cf" xml:lang="en-US"> Warrant exercise price per share </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockWarrantsExercisePricess" xlink:label="gthp_CommonStockWarrantsExercisePricess"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockWarrantsExercisePricess" xlink:to="gthp_CommonStockWarrantsExercisePricess_lbl_c123e6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockWarrantsExercisePricess_lbl_c123e6" xml:lang="en-US"> Common stock warrants exercise price one </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestAndDividendsPayableCurrent" xlink:label="us-gaap_InterestAndDividendsPayableCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InterestAndDividendsPayableCurrent" xlink:to="us-gaap_InterestAndDividendsPayableCurrent_lbl_9c7c51" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InterestAndDividendsPayableCurrent_lbl_9c7c51" xml:lang="en-US"> Accrued dividends </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IncreasedElectionHolder" xlink:label="gthp_IncreasedElectionHolder"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IncreasedElectionHolder" xlink:to="gthp_IncreasedElectionHolder_lbl_0be115" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IncreasedElectionHolder_lbl_0be115" xml:lang="en-US"> Increased election holder </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NumberOfSharesConvertedIntoCommonStock" xlink:label="gthp_NumberOfSharesConvertedIntoCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NumberOfSharesConvertedIntoCommonStock" xlink:to="gthp_NumberOfSharesConvertedIntoCommonStock_lbl_9dd3c0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NumberOfSharesConvertedIntoCommonStock_lbl_9dd3c0" xml:lang="en-US"> Number of shares converted into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SharesIssuedCommonStock" xlink:label="gthp_SharesIssuedCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SharesIssuedCommonStock" xlink:to="gthp_SharesIssuedCommonStock_lbl_a83f66" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SharesIssuedCommonStock_lbl_a83f66" xml:lang="en-US"> Shares issued common stock amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SharesConvertedIntoCommonStock" xlink:label="gthp_SharesConvertedIntoCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SharesConvertedIntoCommonStock" xlink:to="gthp_SharesConvertedIntoCommonStock_lbl_c4e95c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SharesConvertedIntoCommonStock_lbl_c4e95c" xml:lang="en-US"> Shares converted into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CumulativeDividendRate" xlink:label="gthp_CumulativeDividendRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CumulativeDividendRate" xlink:to="gthp_CumulativeDividendRate_lbl_2525aa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CumulativeDividendRate_lbl_2525aa" xml:lang="en-US"> Cumulative dividend rate </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForPaymentPfAnnualSeries" xlink:label="gthp_IssuanceOfCommonStockForPaymentPfAnnualSeries"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForPaymentPfAnnualSeries" xlink:to="gthp_IssuanceOfCommonStockForPaymentPfAnnualSeries_lbl_31a043" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForPaymentPfAnnualSeries_lbl_31a043" xml:lang="en-US"> Issuance of common stock for payment pf annual series </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CumulativeDividends" xlink:to="us-gaap_CumulativeDividends_lbl_b41a4d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_CumulativeDividends_lbl_b41a4d" xml:lang="en-US"> Accrued dividends </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CumulativeDividends" xlink:label="us-gaap_CumulativeDividends"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CumulativeDividends" xlink:to="us-gaap_CumulativeDividends_lbl_57" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CumulativeDividends_lbl_57" xml:lang="en-US"> [Cumulative Dividends] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesAuthorized" xlink:to="us-gaap_PreferredStockSharesAuthorized_lbl_5737cb" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_PreferredStockSharesAuthorized_lbl_5737cb" xml:lang="en-US"> Preferred stock shares authorized </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStockStatedValuePerShare" xlink:label="gthp_PreferredStockStatedValuePerShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStockStatedValuePerShare" xlink:to="gthp_PreferredStockStatedValuePerShare_lbl_00a3d2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStockStatedValuePerShare_lbl_00a3d2" xml:lang="en-US"> Preferred stock stated value </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_CommonStockSharesIssuedForPreferredStockDividends" xlink:label="gthp_CommonStockSharesIssuedForPreferredStockDividends"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_CommonStockSharesIssuedForPreferredStockDividends" xlink:to="gthp_CommonStockSharesIssuedForPreferredStockDividends_lbl_230e26" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_CommonStockSharesIssuedForPreferredStockDividends_lbl_230e26" xml:lang="en-US"> Common stock shares issued for preferred stock dividends </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfCommonStockForConversionOfSeriesEConvertiblePreferredStock" xlink:label="gthp_IssuanceOfCommonStockForConversionOfSeriesEConvertiblePreferredStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfCommonStockForConversionOfSeriesEConvertiblePreferredStock" xlink:to="gthp_IssuanceOfCommonStockForConversionOfSeriesEConvertiblePreferredStock_lbl_6fe4fa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfCommonStockForConversionOfSeriesEConvertiblePreferredStock_lbl_6fe4fa" xml:lang="en-US"> Issuance of common stock for conversion of Series E Convertible Preferred Stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NumberOfSharesConvertedToCommonStock" xlink:label="gthp_NumberOfSharesConvertedToCommonStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NumberOfSharesConvertedToCommonStock" xlink:to="gthp_NumberOfSharesConvertedToCommonStock_lbl_719fea" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NumberOfSharesConvertedToCommonStock_lbl_719fea" xml:lang="en-US"> Number of shares converted to common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IncrementalCommonSharesAttributableToConversionOfDebtSecurity" xlink:label="gthp_IncrementalCommonSharesAttributableToConversionOfDebtSecurity"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IncrementalCommonSharesAttributableToConversionOfDebtSecurity" xlink:to="gthp_IncrementalCommonSharesAttributableToConversionOfDebtSecurity_lbl_f3bd38" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IncrementalCommonSharesAttributableToConversionOfDebtSecurity_lbl_f3bd38" xml:lang="en-US"> Total convertible common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_BlackScholesOptionPricingModelMember" xlink:label="gthp_BlackScholesOptionPricingModelMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_BlackScholesOptionPricingModelMember" xlink:to="gthp_BlackScholesOptionPricingModelMember_lbl_88404d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_BlackScholesOptionPricingModelMember_lbl_88404d" xml:lang="en-US"> Black-Scholes option </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExpectedTermYears" xlink:label="gthp_ExpectedTermYears"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExpectedTermYears" xlink:to="gthp_ExpectedTermYears_lbl_dcebb9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExpectedTermYears_lbl_dcebb9" xml:lang="en-US"> Expected term (years) </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionExpectedVolatilityRate" xlink:to="gthp_FairValueAssumptionExpectedVolatilityRate_lbl_4a134d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_FairValueAssumptionExpectedVolatilityRate_lbl_4a134d" xml:lang="en-US"> Volatility </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_FairValueAssumptionExpectedVolatilityRate" xlink:label="gthp_FairValueAssumptionExpectedVolatilityRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionExpectedVolatilityRate" xlink:to="gthp_FairValueAssumptionExpectedVolatilityRate_lbl_3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_FairValueAssumptionExpectedVolatilityRate_lbl_3" xml:lang="en-US"> [Volatility] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionRiskFreeInterestRate" xlink:to="gthp_FairValueAssumptionRiskFreeInterestRate_lbl_a37905" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_FairValueAssumptionRiskFreeInterestRate_lbl_a37905" xml:lang="en-US"> Risk-free interest rate </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_FairValueAssumptionRiskFreeInterestRate" xlink:label="gthp_FairValueAssumptionRiskFreeInterestRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionRiskFreeInterestRate" xlink:to="gthp_FairValueAssumptionRiskFreeInterestRate_lbl_4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_FairValueAssumptionRiskFreeInterestRate_lbl_4" xml:lang="en-US"> [Risk-free interest rate] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionExpectedDividendRate" xlink:to="gthp_FairValueAssumptionExpectedDividendRate_lbl_8d4765" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_FairValueAssumptionExpectedDividendRate_lbl_8d4765" xml:lang="en-US"> Dividend yield </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_FairValueAssumptionExpectedDividendRate" xlink:label="gthp_FairValueAssumptionExpectedDividendRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionExpectedDividendRate" xlink:to="gthp_FairValueAssumptionExpectedDividendRate_lbl_5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_FairValueAssumptionExpectedDividendRate_lbl_5" xml:lang="en-US"> [Dividend yield] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_OutstandingAtBeginningOfYear" xlink:label="gthp_OutstandingAtBeginningOfYear"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_OutstandingAtBeginningOfYear" xlink:to="gthp_OutstandingAtBeginningOfYear_lbl_347e0f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_OutstandingAtBeginningOfYear_lbl_347e0f" xml:lang="en-US"> Outstanding at beginning of year </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_OptionsGranted" xlink:label="gthp_OptionsGranted"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_OptionsGranted" xlink:to="gthp_OptionsGranted_lbl_856787" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_OptionsGranted_lbl_856787" xml:lang="en-US"> Options granted </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionForfeitureInPeriod" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionForfeitureInPeriod"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionForfeitureInPeriod" xlink:to="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionForfeitureInPeriod_lbl_d1000b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionForfeitureInPeriod_lbl_d1000b" xml:lang="en-US"> Options forfeited </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_OutstandingEnd" xlink:label="gthp_OutstandingEnd"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_OutstandingEnd" xlink:to="gthp_OutstandingEnd_lbl_0bcbb4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_OutstandingEnd_lbl_0bcbb4" xml:lang="en-US"> Outstanding at ending of year </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NumberOfSharesExercisable" xlink:label="gthp_NumberOfSharesExercisable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NumberOfSharesExercisable" xlink:to="gthp_NumberOfSharesExercisable_lbl_945d98" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NumberOfSharesExercisable_lbl_945d98" xml:lang="en-US"> Number of shares exercisable </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1" xlink:to="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1_lbl_3b8262" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1_lbl_3b8262" xml:lang="en-US"> Options outstanding weighted average exercise price, beginning </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1" xlink:to="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1_lbl_7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1_lbl_7" xml:lang="en-US"> [Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_lbl_0a0c5f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_lbl_0a0c5f" xml:lang="en-US"> Options granted weighted average exercise price </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_lbl_4f5581" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_lbl_4f5581" xml:lang="en-US"> Options forfeited weighted average exercise price </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1" xlink:to="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1_lbl_3c41aa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1_lbl_3c41aa" xml:lang="en-US"> Options outstanding weighted average exercise price, Ending </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WeightedAverageExercisePricePerShareExercisable" xlink:label="gthp_WeightedAverageExercisePricePerShareExercisable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WeightedAverageExercisePricePerShareExercisable" xlink:to="gthp_WeightedAverageExercisePricePerShareExercisable_lbl_9edf84" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WeightedAverageExercisePricePerShareExercisable_lbl_9edf84" xml:lang="en-US"> Weighted average exercise price per share exercisable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WeightedAverageRemainingContractualLifeBeginning" xlink:label="gthp_WeightedAverageRemainingContractualLifeBeginning"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WeightedAverageRemainingContractualLifeBeginning" xlink:to="gthp_WeightedAverageRemainingContractualLifeBeginning_lbl_25d163" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WeightedAverageRemainingContractualLifeBeginning_lbl_25d163" xml:lang="en-US"> Weighted average remaining contractual life, Beginning </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WeightedAverageRemainingContractualLifeEnding" xlink:label="gthp_WeightedAverageRemainingContractualLifeEnding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WeightedAverageRemainingContractualLifeEnding" xlink:to="gthp_WeightedAverageRemainingContractualLifeEnding_lbl_7476a4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WeightedAverageRemainingContractualLifeEnding_lbl_7476a4" xml:lang="en-US"> Weighted average remaining contractual life, Ending </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WeightedAverageRemainingContractualLifeExercisable" xlink:label="gthp_WeightedAverageRemainingContractualLifeExercisable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WeightedAverageRemainingContractualLifeExercisable" xlink:to="gthp_WeightedAverageRemainingContractualLifeExercisable_lbl_1b011f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WeightedAverageRemainingContractualLifeExercisable_lbl_1b011f" xml:lang="en-US"> Weighted average remaining contractual life exercisable </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AgrregateIntrensicValue" xlink:to="gthp_AgrregateIntrensicValue_lbl_2d1c25" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="gthp_AgrregateIntrensicValue_lbl_2d1c25" xml:lang="en-US"> Agrregate intrensic value, Beginning </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AgrregateIntrensicValue" xlink:label="gthp_AgrregateIntrensicValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AgrregateIntrensicValue" xlink:to="gthp_AgrregateIntrensicValue_lbl_15" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AgrregateIntrensicValue_lbl_15" xml:lang="en-US"> [Agrregate intrensic value, Beginning] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AgrregateIntrensicValue" xlink:to="gthp_AgrregateIntrensicValue_lbl_234bd1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="gthp_AgrregateIntrensicValue_lbl_234bd1" xml:lang="en-US"> Agrregate intrensic value, Ending </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AgrregateIntrensicValueExercisable" xlink:label="gthp_AgrregateIntrensicValueExercisable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AgrregateIntrensicValueExercisable" xlink:to="gthp_AgrregateIntrensicValueExercisable_lbl_950ab5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AgrregateIntrensicValueExercisable_lbl_950ab5" xml:lang="en-US"> Agrregate intrensic value exercisable </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExpectedTermYears" xlink:to="gthp_ExpectedTermYears_lbl_54b7df" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_ExpectedTermYears_lbl_54b7df" xml:lang="en-US"> Expected term (years) </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionExpectedVolatilityRate" xlink:to="gthp_FairValueAssumptionExpectedVolatilityRate_lbl_e8c713" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:label="gthp_FairValueAssumptionExpectedVolatilityRate_lbl_e8c713" xml:lang="en-US"> Volatility </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionRiskFreeInterestRate" xlink:to="gthp_FairValueAssumptionRiskFreeInterestRate_lbl_526ecd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:label="gthp_FairValueAssumptionRiskFreeInterestRate_lbl_526ecd" xml:lang="en-US"> Risk-free interest rate </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_FairValueAssumptionExpectedDividendRate" xlink:to="gthp_FairValueAssumptionExpectedDividendRate_lbl_0ef418" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:label="gthp_FairValueAssumptionExpectedDividendRate_lbl_0ef418" xml:lang="en-US"> Dividend yield </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_DirectorMember" xlink:label="srt_DirectorMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="srt_DirectorMember" xlink:to="srt_DirectorMember_lbl_c04d05" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="srt_DirectorMember_lbl_c04d05" xml:lang="en-US"> Executive and directors [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AlanGurjicMember" xlink:label="gthp_AlanGurjicMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AlanGurjicMember" xlink:to="gthp_AlanGurjicMember_lbl_177e11" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AlanGurjicMember_lbl_177e11" xml:lang="en-US"> Alan Gurjic [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MrCartwrightMember" xlink:label="gthp_MrCartwrightMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MrCartwrightMember" xlink:to="gthp_MrCartwrightMember_lbl_d8a4dd" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MrCartwrightMember_lbl_d8a4dd" xml:lang="en-US"> Mr. Cartwright [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_UnrecognizedStockBasedCompensationExpense" xlink:label="gthp_UnrecognizedStockBasedCompensationExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_UnrecognizedStockBasedCompensationExpense" xlink:to="gthp_UnrecognizedStockBasedCompensationExpense_lbl_9a6a63" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_UnrecognizedStockBasedCompensationExpense_lbl_9a6a63" xml:lang="en-US"> Unrecognized stock-based compensation expense </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_lbl_73c2ab" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_lbl_73c2ab" xml:lang="en-US"> Weighted average period </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:to="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_lbl_464525" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_lbl_464525" xml:lang="en-US"> Options granted weighted average exercise price </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExercisePrice" xlink:label="gthp_ExercisePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExercisePrice" xlink:to="gthp_ExercisePrice_lbl_df7c8f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExercisePrice_lbl_df7c8f" xml:lang="en-US"> Exercise price </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_OptionsGranted" xlink:to="gthp_OptionsGranted_lbl_744dda" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_OptionsGranted_lbl_744dda" xml:lang="en-US"> Options granted </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MaturityDate" xlink:label="gthp_MaturityDate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MaturityDate" xlink:to="gthp_MaturityDate_lbl_2bcaa7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MaturityDate_lbl_2bcaa7" xml:lang="en-US"> Maturity date </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:label="us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:to="us-gaap_EquityMethodInvestmentOwnershipPercentage_lbl_ece624" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_EquityMethodInvestmentOwnershipPercentage_lbl_ece624" xml:lang="en-US"> Stock options granted outstanding common stock shares percentage </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_VestingPeriodDescription" xlink:label="gthp_VestingPeriodDescription"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_VestingPeriodDescription" xlink:to="gthp_VestingPeriodDescription_lbl_4f2897" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_VestingPeriodDescription_lbl_4f2897" xml:lang="en-US"> Vesting period, description </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockBasedCompensationExpense" xlink:to="gthp_StockBasedCompensationExpense_lbl_1a2a8e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_StockBasedCompensationExpense_lbl_1a2a8e" xml:lang="en-US"> Stock-based compensation expense </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_StockBasedCompensationExpense" xlink:label="gthp_StockBasedCompensationExpense"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_StockBasedCompensationExpense" xlink:to="gthp_StockBasedCompensationExpense_lbl_10" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_StockBasedCompensationExpense_lbl_10" xml:lang="en-US"> [Stock-based compensation expense] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares_lbl_09f658" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares_lbl_09f658" xml:lang="en-US"> Unvested stock options forfeited </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockOptionPlanExpense" xlink:to="us-gaap_StockOptionPlanExpense_lbl_3bb180" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_StockOptionPlanExpense_lbl_3bb180" xml:lang="en-US"> Stock option expense </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseRightOfUseAsset" xlink:to="us-gaap_OperatingLeaseRightOfUseAsset_lbl_82483d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_OperatingLeaseRightOfUseAsset_lbl_82483d" xml:lang="en-US"> Operating lease right-of-use assets </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiability" xlink:label="us-gaap_OperatingLeaseLiability"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="us-gaap_OperatingLeaseLiability_lbl_d59a6d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_OperatingLeaseLiability_lbl_d59a6d" xml:lang="en-US"> Operating lease liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_lbl_3ca971" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_lbl_3ca971" xml:lang="en-US"> 2023 (remaining) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_lbl_9b44e9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_lbl_9b44e9" xml:lang="en-US"> 2024 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_lbl_f7eff3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_lbl_f7eff3" xml:lang="en-US"> 2025 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_lbl_e50480" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_lbl_e50480" xml:lang="en-US"> 2026 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_lbl_b22b0d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_lbl_b22b0d" xml:lang="en-US"> Total future lease payments </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_lbl_20faeb" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_lbl_20faeb" xml:lang="en-US"> Less: discount </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_lbl_7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_lbl_7" xml:lang="en-US"> [Lessee, Operating Lease, Liability, Undiscounted Excess Amount] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="us-gaap_OperatingLeaseLiability_lbl_aad9aa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_OperatingLeaseLiability_lbl_aad9aa" xml:lang="en-US"> Total lease liabilities </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetWeightedAveragePeriodBeforeNextRenewalOrExtension" xlink:label="us-gaap_FiniteLivedIntangibleAssetWeightedAveragePeriodBeforeNextRenewalOrExtension"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FiniteLivedIntangibleAssetWeightedAveragePeriodBeforeNextRenewalOrExtension" xlink:to="us-gaap_FiniteLivedIntangibleAssetWeightedAveragePeriodBeforeNextRenewalOrExtension_lbl_a2f31b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FiniteLivedIntangibleAssetWeightedAveragePeriodBeforeNextRenewalOrExtension_lbl_a2f31b" xml:lang="en-US"> Weighted average remaining lease term (years) </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WeightedAverageDiscountRateoperatingLease" xlink:label="gthp_WeightedAverageDiscountRateoperatingLease"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WeightedAverageDiscountRateoperatingLease" xlink:to="gthp_WeightedAverageDiscountRateoperatingLease_lbl_0bd0e9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WeightedAverageDiscountRateoperatingLease_lbl_0bd0e9" xml:lang="en-US"> Weighted average discount rate </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RichardBlumbergMember" xlink:to="gthp_RichardBlumbergMember_lbl_f271ad" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_RichardBlumbergMember_lbl_f271ad" xml:lang="en-US"> Richard Blumberg [Member] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:to="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_lbl_5663e1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_lbl_5663e1" xml:lang="en-US"> Expected term (years) </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_lbl_1fada5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_lbl_1fada5" xml:lang="en-US"> Volatility </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_lbl_d748b3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_lbl_d748b3" xml:lang="en-US"> Risk-free interest rate </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:to="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_lbl_3eb371" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_lbl_3eb371" xml:lang="en-US"> Dividend yield </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_TitleOfIndividualAxis" xlink:label="srt_TitleOfIndividualAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="srt_TitleOfIndividualAxis" xlink:to="srt_TitleOfIndividualAxis_lbl_4bb6e2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="srt_TitleOfIndividualAxis_lbl_4bb6e2" xml:lang="en-US"> Title of Individual [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_RestatementAxis" xlink:label="srt_RestatementAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="srt_RestatementAxis" xlink:to="srt_RestatementAxis_lbl_f3a84f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="srt_RestatementAxis_lbl_f3a84f" xml:lang="en-US"> Revision of Prior Period [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConsultingAgreementMember" xlink:label="gthp_ConsultingAgreementMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConsultingAgreementMember" xlink:to="gthp_ConsultingAgreementMember_lbl_bf578e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConsultingAgreementMember_lbl_bf578e" xml:lang="en-US"> Consulting Agreement [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AdvisoryGroupMember" xlink:label="gthp_AdvisoryGroupMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AdvisoryGroupMember" xlink:to="gthp_AdvisoryGroupMember_lbl_eaf8ff" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AdvisoryGroupMember_lbl_eaf8ff" xml:lang="en-US"> Advisory Group </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IronstoneCapitalCorpAndAlanGurjicMember" xlink:label="gthp_IronstoneCapitalCorpAndAlanGurjicMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IronstoneCapitalCorpAndAlanGurjicMember" xlink:to="gthp_IronstoneCapitalCorpAndAlanGurjicMember_lbl_ece543" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IronstoneCapitalCorpAndAlanGurjicMember_lbl_ece543" xml:lang="en-US"> Ironstone capital corp and Alan Gurjic </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MrBlumbergMember" xlink:label="gthp_MrBlumbergMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MrBlumbergMember" xlink:to="gthp_MrBlumbergMember_lbl_b8d383" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MrBlumbergMember_lbl_b8d383" xml:lang="en-US"> Mr. Blumberg </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShandongYaohuaMedicalInstrumentCorporationMember" xlink:label="gthp_ShandongYaohuaMedicalInstrumentCorporationMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShandongYaohuaMedicalInstrumentCorporationMember" xlink:to="gthp_ShandongYaohuaMedicalInstrumentCorporationMember_lbl_6765eb" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShandongYaohuaMedicalInstrumentCorporationMember_lbl_6765eb" xml:lang="en-US"> Shandong Yaohua Medical Instrument Corporation [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PromotionalAgreementMember" xlink:label="gthp_PromotionalAgreementMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PromotionalAgreementMember" xlink:to="gthp_PromotionalAgreementMember_lbl_1a51bf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PromotionalAgreementMember_lbl_1a51bf" xml:lang="en-US"> Promotional Agreement [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RoyaltyAgreementMember" xlink:label="gthp_RoyaltyAgreementMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RoyaltyAgreementMember" xlink:to="gthp_RoyaltyAgreementMember_lbl_a8670d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RoyaltyAgreementMember_lbl_a8670d" xml:lang="en-US"> Royalty Agreement [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShenghuoMedicalLLCMember" xlink:label="gthp_ShenghuoMedicalLLCMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShenghuoMedicalLLCMember" xlink:to="gthp_ShenghuoMedicalLLCMember_lbl_a4b747" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShenghuoMedicalLLCMember_lbl_a4b747" xml:lang="en-US"> Shenghuo Medical, LLC [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IronstoneCapitalCorpMember" xlink:label="gthp_IronstoneCapitalCorpMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IronstoneCapitalCorpMember" xlink:to="gthp_IronstoneCapitalCorpMember_lbl_7da048" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IronstoneCapitalCorpMember_lbl_7da048" xml:lang="en-US"> Ironstone Capital Corp [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ThirdPartyMember" xlink:label="gthp_ThirdPartyMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ThirdPartyMember" xlink:to="gthp_ThirdPartyMember_lbl_df9889" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ThirdPartyMember_lbl_df9889" xml:lang="en-US"> Third Party [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_BlackScholesOptionMember" xlink:label="gthp_BlackScholesOptionMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_BlackScholesOptionMember" xlink:to="gthp_BlackScholesOptionMember_lbl_55ada2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_BlackScholesOptionMember_lbl_55ada2" xml:lang="en-US"> Black Scholes Option[Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShareBasedCompensationAwardTrancheSecondAndThirdMember" xlink:label="gthp_ShareBasedCompensationAwardTrancheSecondAndThirdMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShareBasedCompensationAwardTrancheSecondAndThirdMember" xlink:to="gthp_ShareBasedCompensationAwardTrancheSecondAndThirdMember_lbl_7d04c8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShareBasedCompensationAwardTrancheSecondAndThirdMember_lbl_7d04c8" xml:lang="en-US"> Tranche Second and Third [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConsiderationReceived" xlink:label="gthp_ConsiderationReceived"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConsiderationReceived" xlink:to="gthp_ConsiderationReceived_lbl_a432c7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConsiderationReceived_lbl_a432c7" xml:lang="en-US"> Consideration received </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RoyaltyPercent" xlink:label="gthp_RoyaltyPercent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RoyaltyPercent" xlink:to="gthp_RoyaltyPercent_lbl_4da9d1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RoyaltyPercent_lbl_4da9d1" xml:lang="en-US"> Royalty percent </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ClassOfWarrantOrRightOutstanding" xlink:to="us-gaap_ClassOfWarrantOrRightOutstanding_lbl_022cc3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ClassOfWarrantOrRightOutstanding_lbl_022cc3" xml:lang="en-US"> Warrants </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfWarrantOrRightOutstanding" xlink:label="us-gaap_ClassOfWarrantOrRightOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ClassOfWarrantOrRightOutstanding" xlink:to="us-gaap_ClassOfWarrantOrRightOutstanding_lbl_4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ClassOfWarrantOrRightOutstanding_lbl_4" xml:lang="en-US"> [Class of Warrant or Right, Outstanding] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuedAdditionalWarrants" xlink:label="gthp_IssuedAdditionalWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuedAdditionalWarrants" xlink:to="gthp_IssuedAdditionalWarrants_lbl_cd976e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuedAdditionalWarrants_lbl_cd976e" xml:lang="en-US"> Issued additional warrants </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuedWarrants" xlink:label="gthp_IssuedWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuedWarrants" xlink:to="gthp_IssuedWarrants_lbl_34fa1c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuedWarrants_lbl_34fa1c" xml:lang="en-US"> Issued warrants </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExcercisePrice" xlink:label="gthp_ExcercisePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExcercisePrice" xlink:to="gthp_ExcercisePrice_lbl_e8a3f4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExcercisePrice_lbl_e8a3f4" xml:lang="en-US"> Excercise price </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WarrantExercisePriceIncrease" xlink:label="us-gaap_WarrantExercisePriceIncrease"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WarrantExercisePriceIncrease" xlink:to="us-gaap_WarrantExercisePriceIncrease_lbl_0e06a8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WarrantExercisePriceIncrease_lbl_0e06a8" xml:lang="en-US"> Weighted average price </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DescriptionOfAgreement" xlink:label="gthp_DescriptionOfAgreement"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DescriptionOfAgreement" xlink:to="gthp_DescriptionOfAgreement_lbl_8e2c79" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DescriptionOfAgreement_lbl_8e2c79" xml:lang="en-US"> Description of agreement </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantsBrokenIntoFourTranches" xlink:label="gthp_WarrantsBrokenIntoFourTranches"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantsBrokenIntoFourTranches" xlink:to="gthp_WarrantsBrokenIntoFourTranches_lbl_0b9c12" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantsBrokenIntoFourTranches_lbl_0b9c12" xml:lang="en-US"> Warrants broken into four tranches </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RecognizedExpensesForTheWarrants" xlink:label="gthp_RecognizedExpensesForTheWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RecognizedExpensesForTheWarrants" xlink:to="gthp_RecognizedExpensesForTheWarrants_lbl_cb9cf1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RecognizedExpensesForTheWarrants_lbl_cb9cf1" xml:lang="en-US"> Recognized expenses for the warrants </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ExpensesForTheWarrants" xlink:label="gthp_ExpensesForTheWarrants"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ExpensesForTheWarrants" xlink:to="gthp_ExpensesForTheWarrants_lbl_291ec7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ExpensesForTheWarrants_lbl_291ec7" xml:lang="en-US"> Expenses for the warrants </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharePrice" xlink:label="us-gaap_SharePrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharePrice" xlink:to="us-gaap_SharePrice_lbl_d46959" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharePrice_lbl_d46959" xml:lang="en-US"> Strike price </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_EscrowAgentRatePerShare" xlink:label="gthp_EscrowAgentRatePerShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_EscrowAgentRatePerShare" xlink:to="gthp_EscrowAgentRatePerShare_lbl_90595a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_EscrowAgentRatePerShare_lbl_90595a" xml:lang="en-US"> Escrow agent rate per share </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_TermsOfAmendmentToAgreement" xlink:label="gthp_TermsOfAmendmentToAgreement"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_TermsOfAmendmentToAgreement" xlink:to="gthp_TermsOfAmendmentToAgreement_lbl_d349c7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_TermsOfAmendmentToAgreement_lbl_d349c7" xml:lang="en-US"> Terms of amendment to agreement </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RecognizedExpensesForWarrantsIssuedAmount" xlink:label="gthp_RecognizedExpensesForWarrantsIssuedAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RecognizedExpensesForWarrantsIssuedAmount" xlink:to="gthp_RecognizedExpensesForWarrantsIssuedAmount_lbl_d1e6b4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RecognizedExpensesForWarrantsIssuedAmount_lbl_d1e6b4" xml:lang="en-US"> Recognized expenses for Warrants issued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_UnecognizedExpensesForWarrantsIssued" xlink:label="gthp_UnecognizedExpensesForWarrantsIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_UnecognizedExpensesForWarrantsIssued" xlink:to="gthp_UnecognizedExpensesForWarrantsIssued_lbl_c1a0f9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_UnecognizedExpensesForWarrantsIssued_lbl_c1a0f9" xml:lang="en-US"> Unecognized expenses for Warrants issued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RecognizedExpenses" xlink:label="gthp_RecognizedExpenses"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RecognizedExpenses" xlink:to="gthp_RecognizedExpenses_lbl_e87045" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RecognizedExpenses_lbl_e87045" xml:lang="en-US"> Recognized expenses </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockShareSubscribedButUnissuedSubscriptionsReceivable" xlink:label="us-gaap_CommonStockShareSubscribedButUnissuedSubscriptionsReceivable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CommonStockShareSubscribedButUnissuedSubscriptionsReceivable" xlink:to="us-gaap_CommonStockShareSubscribedButUnissuedSubscriptionsReceivable_lbl_9f3b81" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_CommonStockShareSubscribedButUnissuedSubscriptionsReceivable_lbl_9f3b81" xml:lang="en-US"> Subscription receivable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SharesExchangeShareStock" xlink:label="gthp_SharesExchangeShareStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SharesExchangeShareStock" xlink:to="gthp_SharesExchangeShareStock_lbl_d6906c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SharesExchangeShareStock_lbl_d6906c" xml:lang="en-US"> Shares exchange </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ExcessStockSharesIssued" xlink:to="us-gaap_ExcessStockSharesIssued_lbl_e95f84" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ExcessStockSharesIssued_lbl_e95f84" xml:lang="en-US"> Shares exchange </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ExcessStockSharesIssued" xlink:label="us-gaap_ExcessStockSharesIssued"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ExcessStockSharesIssued" xlink:to="us-gaap_ExcessStockSharesIssued_lbl_21" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ExcessStockSharesIssued_lbl_21" xml:lang="en-US"> [Excess Stock, Shares Issued] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SharesExchange" xlink:to="gthp_SharesExchange_lbl_5671b5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_SharesExchange_lbl_5671b5" xml:lang="en-US"> Shares exchange </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SharesExchange" xlink:label="gthp_SharesExchange"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SharesExchange" xlink:to="gthp_SharesExchange_lbl_22" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SharesExchange_lbl_22" xml:lang="en-US"> [Shares exchange] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConsultingExpenses" xlink:label="gthp_ConsultingExpenses"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConsultingExpenses" xlink:to="gthp_ConsultingExpenses_lbl_e983bb" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConsultingExpenses_lbl_e983bb" xml:lang="en-US"> Consulting expenses </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_RoyaltyConsideration" xlink:label="gthp_RoyaltyConsideration"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_RoyaltyConsideration" xlink:to="gthp_RoyaltyConsideration_lbl_c38a05" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_RoyaltyConsideration_lbl_c38a05" xml:lang="en-US"> Royalty consideration </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PaymentReceiveDescriptions" xlink:label="gthp_PaymentReceiveDescriptions"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PaymentReceiveDescriptions" xlink:to="gthp_PaymentReceiveDescriptions_lbl_607b91" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PaymentReceiveDescriptions_lbl_607b91" xml:lang="en-US"> Payment receive descriptions </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DrCartwrightMember" xlink:label="gthp_DrCartwrightMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DrCartwrightMember" xlink:to="gthp_DrCartwrightMember_lbl_8d5a25" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DrCartwrightMember_lbl_8d5a25" xml:lang="en-US"> Dr. Cartwright </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PremiumFinanceInsuranceMember" xlink:label="gthp_PremiumFinanceInsuranceMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PremiumFinanceInsuranceMember" xlink:to="gthp_PremiumFinanceInsuranceMember_lbl_84415f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PremiumFinanceInsuranceMember_lbl_84415f" xml:lang="en-US"> Premium Finance insurance </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShortTermBankLoansAndNotesPayable" xlink:label="us-gaap_ShortTermBankLoansAndNotesPayable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShortTermBankLoansAndNotesPayable" xlink:to="us-gaap_ShortTermBankLoansAndNotesPayable_lbl_b7bf1c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShortTermBankLoansAndNotesPayable_lbl_b7bf1c" xml:lang="en-US"> Short term notes payable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NotesPayableInDefault" xlink:label="gthp_NotesPayableInDefault"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NotesPayableInDefault" xlink:to="gthp_NotesPayableInDefault_lbl_ad0978" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NotesPayableInDefault_lbl_ad0978" xml:lang="en-US"> Notes payable in default, including related parties </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ShortTermNotesPayableDueToRelatedParties" xlink:label="gthp_ShortTermNotesPayableDueToRelatedParties"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ShortTermNotesPayableDueToRelatedParties" xlink:to="gthp_ShortTermNotesPayableDueToRelatedParties_lbl_c583fa" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ShortTermNotesPayableDueToRelatedParties_lbl_c583fa" xml:lang="en-US"> Short-term notes payable due to related parties </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NotesPayable" xlink:label="us-gaap_NotesPayable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NotesPayable" xlink:to="us-gaap_NotesPayable_lbl_fb324f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NotesPayable_lbl_fb324f" xml:lang="en-US"> Outstanding principal balance </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RepaymentsOfDebt" xlink:label="us-gaap_RepaymentsOfDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RepaymentsOfDebt" xlink:to="us-gaap_RepaymentsOfDebt_lbl_90faee" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RepaymentsOfDebt_lbl_90faee" xml:lang="en-US"> Monthly payment </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LineOfCreditFacilityAverageOutstandingAmount" xlink:label="us-gaap_LineOfCreditFacilityAverageOutstandingAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LineOfCreditFacilityAverageOutstandingAmount" xlink:to="us-gaap_LineOfCreditFacilityAverageOutstandingAmount_lbl_8901c3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LineOfCreditFacilityAverageOutstandingAmount_lbl_8901c3" xml:lang="en-US"> Line of credit facility, maximum borrowing capacity </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentMaturityDate" xlink:to="us-gaap_DebtInstrumentMaturityDate_lbl_d37f03" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_DebtInstrumentMaturityDate_lbl_d37f03" xml:lang="en-US"> Maturity date </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtInstrumentMaturityDate" xlink:label="us-gaap_DebtInstrumentMaturityDate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentMaturityDate" xlink:to="us-gaap_DebtInstrumentMaturityDate_lbl_6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtInstrumentMaturityDate_lbl_6" xml:lang="en-US"> [Debt Instrument, Maturity Date] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_NotesInitiallyIssuedWithInterest" xlink:label="gthp_NotesInitiallyIssuedWithInterest"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_NotesInitiallyIssuedWithInterest" xlink:to="gthp_NotesInitiallyIssuedWithInterest_lbl_cdd405" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_NotesInitiallyIssuedWithInterest_lbl_cdd405" xml:lang="en-US"> Notes initially issued with interest </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PercentageOfIncreasedInterest" xlink:label="gthp_PercentageOfIncreasedInterest"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PercentageOfIncreasedInterest" xlink:to="gthp_PercentageOfIncreasedInterest_lbl_dd592c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PercentageOfIncreasedInterest_lbl_dd592c" xml:lang="en-US"> Percentage of increased interest </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NotesIssued1" xlink:label="us-gaap_NotesIssued1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_NotesIssued1" xlink:to="us-gaap_NotesIssued1_lbl_be45e3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_NotesIssued1_lbl_be45e3" xml:lang="en-US"> Promissory notes issued </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities" xlink:label="us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromPaymentsForOtherFinancingActivities" xlink:to="us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_lbl_9e4495" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_lbl_9e4495" xml:lang="en-US"> Financing proceeds received by company </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AccruedInterestRate" xlink:label="gthp_AccruedInterestRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccruedInterestRate" xlink:to="gthp_AccruedInterestRate_lbl_18d548" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AccruedInterestRate_lbl_18d548" xml:lang="en-US"> Accrued interest rate </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SeniorUnsecuredConvertibleDebentures" xlink:label="gthp_SeniorUnsecuredConvertibleDebentures"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SeniorUnsecuredConvertibleDebentures" xlink:to="gthp_SeniorUnsecuredConvertibleDebentures_lbl_78427e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SeniorUnsecuredConvertibleDebentures_lbl_78427e" xml:lang="en-US"> 10% Senior Unsecured Convertible Debentures </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DebtIssuanceCostsAmortized" xlink:label="gthp_DebtIssuanceCostsAmortized"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DebtIssuanceCostsAmortized" xlink:to="gthp_DebtIssuanceCostsAmortized_lbl_a5d965" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DebtIssuanceCostsAmortized_lbl_a5d965" xml:lang="en-US"> Debt Issuance costs to be amortized </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentUnamortizedDiscount" xlink:to="us-gaap_DebtInstrumentUnamortizedDiscount_lbl_a82d53" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_DebtInstrumentUnamortizedDiscount_lbl_a82d53" xml:lang="en-US"> Debt Discount </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtInstrumentUnamortizedDiscount" xlink:label="us-gaap_DebtInstrumentUnamortizedDiscount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentUnamortizedDiscount" xlink:to="us-gaap_DebtInstrumentUnamortizedDiscount_lbl_4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtInstrumentUnamortizedDiscount_lbl_4" xml:lang="en-US"> [Debt Instrument, Unamortized Discount] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertibleLongTermNotesPayable" xlink:to="us-gaap_ConvertibleLongTermNotesPayable_lbl_8268c1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ConvertibleLongTermNotesPayable_lbl_8268c1" xml:lang="en-US"> Long-term convertible debt </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConvertibleLongTermNotesPayable" xlink:label="us-gaap_ConvertibleLongTermNotesPayable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertibleLongTermNotesPayable" xlink:to="us-gaap_ConvertibleLongTermNotesPayable_lbl_5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConvertibleLongTermNotesPayable_lbl_5" xml:lang="en-US"> [Convertible Notes Payable, Noncurrent] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_RangeAxis" xlink:label="srt_RangeAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="srt_RangeAxis" xlink:to="srt_RangeAxis_lbl_76348e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="srt_RangeAxis_lbl_76348e" xml:lang="en-US"> Range [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtInstrumentAxis" xlink:label="us-gaap_DebtInstrumentAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentAxis" xlink:to="us-gaap_DebtInstrumentAxis_lbl_ee8140" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtInstrumentAxis_lbl_ee8140" xml:lang="en-US"> Debt Instrument Axis </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="us-gaap_RelatedPartyTransactionAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_RelatedPartyTransactionAxis" xlink:to="us-gaap_RelatedPartyTransactionAxis_lbl_20794f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_RelatedPartyTransactionAxis_lbl_20794f" xml:lang="en-US"> Related Party Transaction Axis </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="us-gaap_LongtermDebtTypeAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongtermDebtTypeAxis" xlink:to="us-gaap_LongtermDebtTypeAxis_lbl_b9c1f1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongtermDebtTypeAxis_lbl_b9c1f1" xml:lang="en-US"> Longterm Debt Type Axis </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_MinimumMember" xlink:label="srt_MinimumMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="srt_MinimumMember" xlink:to="srt_MinimumMember_lbl_426707" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="srt_MinimumMember_lbl_426707" xml:lang="en-US"> Minimum </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2023/elts/srt-2023.xsd#srt_MaximumMember" xlink:label="srt_MaximumMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="srt_MaximumMember" xlink:to="srt_MaximumMember_lbl_9949bf" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="srt_MaximumMember_lbl_9949bf" xml:lang="en-US"> Maximum </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantOneMember" xlink:label="gthp_WarrantOneMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantOneMember" xlink:to="gthp_WarrantOneMember_lbl_39980b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantOneMember_lbl_39980b" xml:lang="en-US"> Warrant One [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantTwoMember" xlink:label="gthp_WarrantTwoMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantTwoMember" xlink:to="gthp_WarrantTwoMember_lbl_795852" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantTwoMember_lbl_795852" xml:lang="en-US"> Warrant Two [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AuctusMember" xlink:label="gthp_AuctusMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AuctusMember" xlink:to="gthp_AuctusMember_lbl_10f26a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AuctusMember_lbl_10f26a" xml:lang="en-US"> Auctus [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_TenPercentSeniorUnsecuredConvertibleDebentureMember" xlink:label="gthp_TenPercentSeniorUnsecuredConvertibleDebentureMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_TenPercentSeniorUnsecuredConvertibleDebentureMember" xlink:to="gthp_TenPercentSeniorUnsecuredConvertibleDebentureMember_lbl_3e0a46" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_TenPercentSeniorUnsecuredConvertibleDebentureMember_lbl_3e0a46" xml:lang="en-US"> 10% Senior Unsecured Convertible Debenture </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConvertibleDebt" xlink:label="us-gaap_ConvertibleDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertibleDebt" xlink:to="us-gaap_ConvertibleDebt_lbl_57646c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConvertibleDebt_lbl_57646c" xml:lang="en-US"> Convertible promissory note </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConvertibleDebtConversionPriceDescription" xlink:label="gthp_ConvertibleDebtConversionPriceDescription"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConvertibleDebtConversionPriceDescription" xlink:to="gthp_ConvertibleDebtConversionPriceDescription_lbl_5cee9b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConvertibleDebtConversionPriceDescription_lbl_5cee9b" xml:lang="en-US"> Convertible debt conversion price description </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SharesIssuedPricePerShare" xlink:label="us-gaap_SharesIssuedPricePerShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SharesIssuedPricePerShare" xlink:to="us-gaap_SharesIssuedPricePerShare_lbl_ab90ec" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SharesIssuedPricePerShare_lbl_ab90ec" xml:lang="en-US"> Trading price </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_VariableConversionPrice" xlink:label="gthp_VariableConversionPrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_VariableConversionPrice" xlink:to="gthp_VariableConversionPrice_lbl_61aa6a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_VariableConversionPrice_lbl_61aa6a" xml:lang="en-US"> Variable conversion price </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_EarlyRepaymentOfSeniorDebtPenalty" xlink:label="gthp_EarlyRepaymentOfSeniorDebtPenalty"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_EarlyRepaymentOfSeniorDebtPenalty" xlink:to="gthp_EarlyRepaymentOfSeniorDebtPenalty_lbl_3914ab" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_EarlyRepaymentOfSeniorDebtPenalty_lbl_3914ab" xml:lang="en-US"> Early prepayment penalty </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DefaultPremiums" xlink:label="gthp_DefaultPremiums"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DefaultPremiums" xlink:to="gthp_DefaultPremiums_lbl_432ea1" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DefaultPremiums_lbl_432ea1" xml:lang="en-US"> Default premiums </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_InterestPayable" xlink:label="gthp_InterestPayable"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_InterestPayable" xlink:to="gthp_InterestPayable_lbl_6943f0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_InterestPayable_lbl_6943f0" xml:lang="en-US"> Interest payable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AmountReduceAfterExchange" xlink:label="gthp_AmountReduceAfterExchange"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AmountReduceAfterExchange" xlink:to="gthp_AmountReduceAfterExchange_lbl_8b21c2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AmountReduceAfterExchange_lbl_8b21c2" xml:lang="en-US"> Reduced amount owed to Auctus after the Exchange </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_WarrantExchange" xlink:label="gthp_WarrantExchange"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantExchange" xlink:to="gthp_WarrantExchange_lbl_441e27" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_WarrantExchange_lbl_441e27" xml:lang="en-US"> Warrants exchanged by Auctus </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WarrantExercisePriceIncrease" xlink:to="us-gaap_WarrantExercisePriceIncrease_lbl_e077b6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_WarrantExercisePriceIncrease_lbl_e077b6" xml:lang="en-US"> Warrant exchange price </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConvertibleNotesPayableCurrent" xlink:label="us-gaap_ConvertibleNotesPayableCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertibleNotesPayableCurrent" xlink:to="us-gaap_ConvertibleNotesPayableCurrent_lbl_72da7e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConvertibleNotesPayableCurrent_lbl_72da7e" xml:lang="en-US"> Short term convertible note payable </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertibleLongTermNotesPayable" xlink:to="us-gaap_ConvertibleLongTermNotesPayable_lbl_947318" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:label="us-gaap_ConvertibleLongTermNotesPayable_lbl_947318" xml:lang="en-US"> Long term convertible debt </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockIssuedDuringPeriodSharesOther" xlink:label="us-gaap_StockIssuedDuringPeriodSharesOther"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockIssuedDuringPeriodSharesOther" xlink:to="us-gaap_StockIssuedDuringPeriodSharesOther_lbl_94de32" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockIssuedDuringPeriodSharesOther_lbl_94de32" xml:lang="en-US"> Share Issue </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockRepurchaseProgramRemainingNumberOfSharesAuthorizedToBeRepurchased" xlink:label="us-gaap_StockRepurchaseProgramRemainingNumberOfSharesAuthorizedToBeRepurchased"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockRepurchaseProgramRemainingNumberOfSharesAuthorizedToBeRepurchased" xlink:to="us-gaap_StockRepurchaseProgramRemainingNumberOfSharesAuthorizedToBeRepurchased_lbl_250840" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockRepurchaseProgramRemainingNumberOfSharesAuthorizedToBeRepurchased_lbl_250840" xml:lang="en-US"> Warrant to purchase </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DebtInstrumentDefaultPenaltyForgiven" xlink:label="gthp_DebtInstrumentDefaultPenaltyForgiven"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DebtInstrumentDefaultPenaltyForgiven" xlink:to="gthp_DebtInstrumentDefaultPenaltyForgiven_lbl_182604" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DebtInstrumentDefaultPenaltyForgiven_lbl_182604" xml:lang="en-US"> Default penalty forgiven by Auctus </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LossOnExtinguishmentOfDebt" xlink:label="gthp_LossOnExtinguishmentOfDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LossOnExtinguishmentOfDebt" xlink:to="gthp_LossOnExtinguishmentOfDebt_lbl_811a2b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LossOnExtinguishmentOfDebt_lbl_811a2b" xml:lang="en-US"> Loss on extinguishment of debt </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:to="us-gaap_DebtInstrumentInterestRateStatedPercentage_lbl_f6d57d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtInstrumentInterestRateStatedPercentage_lbl_f6d57d" xml:lang="en-US"> Interest rate </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PrepaidRent" xlink:label="us-gaap_PrepaidRent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PrepaidRent" xlink:to="us-gaap_PrepaidRent_lbl_a417c7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PrepaidRent_lbl_a417c7" xml:lang="en-US"> Prepayment penalty </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AggregateBalanceOfTheConvertibleDebtOutstanding" xlink:label="gthp_AggregateBalanceOfTheConvertibleDebtOutstanding"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AggregateBalanceOfTheConvertibleDebtOutstanding" xlink:to="gthp_AggregateBalanceOfTheConvertibleDebtOutstanding_lbl_eb0315" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AggregateBalanceOfTheConvertibleDebtOutstanding_lbl_eb0315" xml:lang="en-US"> Total balance of the convertible debt outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DepositLiabilitiesAccruedInterest" xlink:label="us-gaap_DepositLiabilitiesAccruedInterest"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DepositLiabilitiesAccruedInterest" xlink:to="us-gaap_DepositLiabilitiesAccruedInterest_lbl_d03aca" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DepositLiabilitiesAccruedInterest_lbl_d03aca" xml:lang="en-US"> Accrued interest </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ConvertibleDebenturesRightDescription" xlink:label="gthp_ConvertibleDebenturesRightDescription"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ConvertibleDebenturesRightDescription" xlink:to="gthp_ConvertibleDebenturesRightDescription_lbl_43ae9d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ConvertibleDebenturesRightDescription_lbl_43ae9d" xml:lang="en-US"> Convertible debentures right description </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_ChangeOfControlPremiumPercentage" xlink:label="gthp_ChangeOfControlPremiumPercentage"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_ChangeOfControlPremiumPercentage" xlink:to="gthp_ChangeOfControlPremiumPercentage_lbl_2c3aa5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_ChangeOfControlPremiumPercentage_lbl_2c3aa5" xml:lang="en-US"> Change of Control premium percentage </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InvestmentInterestRate" xlink:label="us-gaap_InvestmentInterestRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InvestmentInterestRate" xlink:to="us-gaap_InvestmentInterestRate_lbl_18eb7d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InvestmentInterestRate_lbl_18eb7d" xml:lang="en-US"> Senior Secured Convertible rate </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DeemedPrice" xlink:label="gthp_DeemedPrice"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DeemedPrice" xlink:to="gthp_DeemedPrice_lbl_41e92d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DeemedPrice_lbl_41e92d" xml:lang="en-US"> Deemed price </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DebtMaturityDate" xlink:label="gthp_DebtMaturityDate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DebtMaturityDate" xlink:to="gthp_DebtMaturityDate_lbl_e98329" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DebtMaturityDate_lbl_e98329" xml:lang="en-US"> Debt maturity date </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromIssuanceOfUnsecuredDebt" xlink:label="us-gaap_ProceedsFromIssuanceOfUnsecuredDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProceedsFromIssuanceOfUnsecuredDebt" xlink:to="us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_lbl_319dbc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_lbl_319dbc" xml:lang="en-US"> Proceeds from convertible debenture </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtInstrumentConvertibleConversionPrice1" xlink:label="us-gaap_DebtInstrumentConvertibleConversionPrice1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentConvertibleConversionPrice1" xlink:to="us-gaap_DebtInstrumentConvertibleConversionPrice1_lbl_2821b8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtInstrumentConvertibleConversionPrice1_lbl_2821b8" xml:lang="en-US"> Conversion price </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DrFaupelMember" xlink:label="gthp_DrFaupelMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DrFaupelMember" xlink:to="gthp_DrFaupelMember_lbl_b4b27b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DrFaupelMember_lbl_b4b27b" xml:lang="en-US"> Dr. Faupel </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccruedSalariesCurrentAndNoncurrent" xlink:label="us-gaap_AccruedSalariesCurrentAndNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedSalariesCurrentAndNoncurrent" xlink:to="us-gaap_AccruedSalariesCurrentAndNoncurrent_lbl_0b89ff" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AccruedSalariesCurrentAndNoncurrent_lbl_0b89ff" xml:lang="en-US"> Salary </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedBonusesCurrentAndNoncurrent" xlink:to="us-gaap_AccruedBonusesCurrentAndNoncurrent_lbl_a7b77b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_AccruedBonusesCurrentAndNoncurrent_lbl_a7b77b" xml:lang="en-US"> Bonus </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AccruedVacationCurrentAndNoncurrent" xlink:to="us-gaap_AccruedVacationCurrentAndNoncurrent_lbl_e12424" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_AccruedVacationCurrentAndNoncurrent_lbl_e12424" xml:lang="en-US"> Vacation </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_InterestOnCompensation" xlink:label="gthp_InterestOnCompensation"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_InterestOnCompensation" xlink:to="gthp_InterestOnCompensation_lbl_87395f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_InterestOnCompensation_lbl_87395f" xml:lang="en-US"> Interest on compensation </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LoansToCompany" xlink:label="gthp_LoansToCompany"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LoansToCompany" xlink:to="gthp_LoansToCompany_lbl_022723" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LoansToCompany_lbl_022723" xml:lang="en-US"> Loans to Company </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_InterestOnLoans" xlink:label="gthp_InterestOnLoans"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_InterestOnLoans" xlink:to="gthp_InterestOnLoans_lbl_7e3487" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_InterestOnLoans_lbl_7e3487" xml:lang="en-US"> Interest on loans </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_TotalOutstandingPriorToExchange" xlink:label="gthp_TotalOutstandingPriorToExchange"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_TotalOutstandingPriorToExchange" xlink:to="gthp_TotalOutstandingPriorToExchange_lbl_a0c923" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_TotalOutstandingPriorToExchange_lbl_a0c923" xml:lang="en-US"> Total outstanding prior to exchange </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentDecreaseForgiveness" xlink:to="us-gaap_DebtInstrumentDecreaseForgiveness_lbl_d972d5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="us-gaap_DebtInstrumentDecreaseForgiveness_lbl_d972d5" xml:lang="en-US"> Amount forgiven in prior years </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtInstrumentDecreaseForgiveness" xlink:label="us-gaap_DebtInstrumentDecreaseForgiveness"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentDecreaseForgiveness" xlink:to="us-gaap_DebtInstrumentDecreaseForgiveness_lbl_9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtInstrumentDecreaseForgiveness_lbl_9" xml:lang="en-US"> [Debt Instrument, Decrease, Forgiveness] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AmountExchangedForSeriesPreferredStock" xlink:label="gthp_AmountExchangedForSeriesPreferredStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AmountExchangedForSeriesPreferredStock" xlink:to="gthp_AmountExchangedForSeriesPreferredStock_lbl_7f0212" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AmountExchangedForSeriesPreferredStock_lbl_7f0212" xml:lang="en-US"> Amount exchanged for Series F-2 Preferred Stock </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AmountExchangedForSeriesF2PreferredStock" xlink:to="gthp_AmountExchangedForSeriesF2PreferredStock_lbl_cd07a2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_AmountExchangedForSeriesF2PreferredStock_lbl_cd07a2" xml:lang="en-US"> Amount exchanged for Series F-2 Preferred Stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AmountExchangedForSeriesF2PreferredStock" xlink:label="gthp_AmountExchangedForSeriesF2PreferredStock"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AmountExchangedForSeriesF2PreferredStock" xlink:to="gthp_AmountExchangedForSeriesF2PreferredStock_lbl_11" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AmountExchangedForSeriesF2PreferredStock_lbl_11" xml:lang="en-US"> [Amount exchanged for Series F-2 Preferred Stock] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestPayableCurrentAndNoncurrent" xlink:label="us-gaap_InterestPayableCurrentAndNoncurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InterestPayableCurrentAndNoncurrent" xlink:to="us-gaap_InterestPayableCurrentAndNoncurrent_lbl_3466dc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InterestPayableCurrentAndNoncurrent_lbl_3466dc" xml:lang="en-US"> Total interest accrued </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PaymentsOnOutstandingDebt" xlink:label="gthp_PaymentsOnOutstandingDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PaymentsOnOutstandingDebt" xlink:to="gthp_PaymentsOnOutstandingDebt_lbl_387873" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PaymentsOnOutstandingDebt_lbl_387873" xml:lang="en-US"> Payments on outstanding debt </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShortTermBorrowings" xlink:label="us-gaap_ShortTermBorrowings"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShortTermBorrowings" xlink:to="us-gaap_ShortTermBorrowings_lbl_ec2739" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShortTermBorrowings_lbl_ec2739" xml:lang="en-US"> Balance outstanding, end of period </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LongTermDebtRelatedPartiesMember" xlink:label="gthp_LongTermDebtRelatedPartiesMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LongTermDebtRelatedPartiesMember" xlink:to="gthp_LongTermDebtRelatedPartiesMember_lbl_191866" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LongTermDebtRelatedPartiesMember_lbl_191866" xml:lang="en-US"> Long-Term Debt - Related Parties </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MrFowlerMember" xlink:label="gthp_MrFowlerMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MrFowlerMember" xlink:to="gthp_MrFowlerMember_lbl_966a8b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MrFowlerMember_lbl_966a8b" xml:lang="en-US"> Mr. Fowler </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_lbl_b2a640" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_lbl_b2a640" xml:lang="en-US"> 2023 </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_lbl_db6cb6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_lbl_db6cb6" xml:lang="en-US"> 2024 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_lbl_3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_lbl_3" xml:lang="en-US"> [Long-Term Debt, Maturity, Year Two] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_lbl_514054" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_lbl_514054" xml:lang="en-US"> 2025 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_lbl_4" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_lbl_4" xml:lang="en-US"> [Long-Term Debt, Maturity, Year Three] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_lbl_485ef8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_lbl_485ef8" xml:lang="en-US"> 2026 </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_lbl_5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_lbl_5" xml:lang="en-US"> [Long-Term Debt, Maturity, Year Four] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_LongTermDebt_lbl_b3663a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_LongTermDebt_lbl_b3663a" xml:lang="en-US"> Total </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LongTermDebt" xlink:label="us-gaap_LongTermDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_LongTermDebt_lbl_6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_LongTermDebt_lbl_6" xml:lang="en-US"> [Long-Term Debt] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MrFowlerMember" xlink:to="gthp_MrFowlerMember_lbl_91e5ae" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_MrFowlerMember_lbl_91e5ae" xml:lang="en-US"> Mr. Fowler </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MrBillWellsMember" xlink:label="gthp_MrBillWellsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MrBillWellsMember" xlink:to="gthp_MrBillWellsMember_lbl_74062d" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MrBillWellsMember_lbl_74062d" xml:lang="en-US"> Mr. Bill Wells </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_SixPercentUnsecuredPromissoryNoteMember" xlink:label="gthp_SixPercentUnsecuredPromissoryNoteMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_SixPercentUnsecuredPromissoryNoteMember" xlink:to="gthp_SixPercentUnsecuredPromissoryNoteMember_lbl_f7d83a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_SixPercentUnsecuredPromissoryNoteMember_lbl_f7d83a" xml:lang="en-US"> 6% Unsecured Promissory Note </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_TotalOutstandingPriorToExchangeValue" xlink:to="gthp_TotalOutstandingPriorToExchangeValue_lbl_bc17b8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_TotalOutstandingPriorToExchangeValue_lbl_bc17b8" xml:lang="en-US"> Total outstanding prior to exchange </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_TotalOutstandingPriorToExchangeValue" xlink:label="gthp_TotalOutstandingPriorToExchangeValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_TotalOutstandingPriorToExchangeValue" xlink:to="gthp_TotalOutstandingPriorToExchangeValue_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_TotalOutstandingPriorToExchangeValue_lbl_2" xml:lang="en-US"> [Total outstanding prior to exchange] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_TotalOutstandingPriorToExchange" xlink:to="gthp_TotalOutstandingPriorToExchange_lbl_e1a926" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_TotalOutstandingPriorToExchange_lbl_e1a926" xml:lang="en-US"> Total outstanding prior to exchange </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PrincipalPayment" xlink:label="gthp_PrincipalPayment"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PrincipalPayment" xlink:to="gthp_PrincipalPayment_lbl_1a3406" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PrincipalPayment_lbl_1a3406" xml:lang="en-US"> Principal payment </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredCompensationEquity" xlink:label="us-gaap_DeferredCompensationEquity"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DeferredCompensationEquity" xlink:to="us-gaap_DeferredCompensationEquity_lbl_0d0cb8" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DeferredCompensationEquity_lbl_0d0cb8" xml:lang="en-US"> Deferred compensation </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LongTermDebtRelatedParties" xlink:label="gthp_LongTermDebtRelatedParties"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LongTermDebtRelatedParties" xlink:to="gthp_LongTermDebtRelatedParties_lbl_be6bd3" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LongTermDebtRelatedParties_lbl_be6bd3" xml:lang="en-US"> Long-term debt-related parties </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_LongTermDebtCurrent" xlink:to="us-gaap_LongTermDebtCurrent_lbl_3d617e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_LongTermDebtCurrent_lbl_3d617e" xml:lang="en-US"> Current portion of long-term debt, related parties </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DueFromToRelatedPartyCurrent" xlink:label="gthp_DueFromToRelatedPartyCurrent"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DueFromToRelatedPartyCurrent" xlink:to="gthp_DueFromToRelatedPartyCurrent_lbl_179851" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DueFromToRelatedPartyCurrent_lbl_179851" xml:lang="en-US"> Due to related party </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PromissoryNoteInterestRate" xlink:label="gthp_PromissoryNoteInterestRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PromissoryNoteInterestRate" xlink:to="gthp_PromissoryNoteInterestRate_lbl_ac27d6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PromissoryNoteInterestRate_lbl_ac27d6" xml:lang="en-US"> Promissory note interest rate </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtConversionConvertedInstrumentAmount1" xlink:label="us-gaap_DebtConversionConvertedInstrumentAmount1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtConversionConvertedInstrumentAmount1" xlink:to="us-gaap_DebtConversionConvertedInstrumentAmount1_lbl_637cbe" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtConversionConvertedInstrumentAmount1_lbl_637cbe" xml:lang="en-US"> Debt instrument converted amount </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtConversionConvertedInstrumentSharesIssued1" xlink:label="us-gaap_DebtConversionConvertedInstrumentSharesIssued1"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtConversionConvertedInstrumentSharesIssued1" xlink:to="us-gaap_DebtConversionConvertedInstrumentSharesIssued1_lbl_0b3925" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtConversionConvertedInstrumentSharesIssued1_lbl_0b3925" xml:lang="en-US"> Series F-2 Preferred Stock issued upon conversion of debt </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_InterestPayableValue" xlink:to="gthp_InterestPayableValue_lbl_626438" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_InterestPayableValue_lbl_626438" xml:lang="en-US"> Interest payable </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_InterestPayableValue" xlink:label="gthp_InterestPayableValue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_InterestPayableValue" xlink:to="gthp_InterestPayableValue_lbl_12" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_InterestPayableValue_lbl_12" xml:lang="en-US"> [Interest payable] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DueToRelatedPartyAmount" xlink:label="gthp_DueToRelatedPartyAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DueToRelatedPartyAmount" xlink:to="gthp_DueToRelatedPartyAmount_lbl_9687f9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DueToRelatedPartyAmount_lbl_9687f9" xml:lang="en-US"> Due to related party, amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PromissoryNoteDefaultInterestRate" xlink:label="gthp_PromissoryNoteDefaultInterestRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PromissoryNoteDefaultInterestRate" xlink:to="gthp_PromissoryNoteDefaultInterestRate_lbl_373024" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PromissoryNoteDefaultInterestRate_lbl_373024" xml:lang="en-US"> Promissory note default interest rate </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DebtInstrumentPeriodicPayment" xlink:label="us-gaap_DebtInstrumentPeriodicPayment"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DebtInstrumentPeriodicPayment" xlink:to="us-gaap_DebtInstrumentPeriodicPayment_lbl_27719f" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DebtInstrumentPeriodicPayment_lbl_27719f" xml:lang="en-US"> Promissory note monthly installment </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion" xlink:label="us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion" xlink:to="us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion_lbl_4014ec" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion_lbl_4014ec" xml:lang="en-US"> Preferred shares converted into common stock </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_EffectiveInterestRate" xlink:label="gthp_EffectiveInterestRate"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_EffectiveInterestRate" xlink:to="gthp_EffectiveInterestRate_lbl_b299ac" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_EffectiveInterestRate_lbl_b299ac" xml:lang="en-US"> Effective interest rate </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DeferredSalary" xlink:label="gthp_DeferredSalary"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DeferredSalary" xlink:to="gthp_DeferredSalary_lbl_35a358" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DeferredSalary_lbl_35a358" xml:lang="en-US"> Deferred salary </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_UnsecuredNoteIssuedUponConversionOfDebt" xlink:label="gthp_UnsecuredNoteIssuedUponConversionOfDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_UnsecuredNoteIssuedUponConversionOfDebt" xlink:to="gthp_UnsecuredNoteIssuedUponConversionOfDebt_lbl_a7753b" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_UnsecuredNoteIssuedUponConversionOfDebt_lbl_a7753b" xml:lang="en-US"> Unsecured note issued upon conversion of debt </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PrincipalAmountOfPromissoryNote" xlink:label="gthp_PrincipalAmountOfPromissoryNote"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PrincipalAmountOfPromissoryNote" xlink:to="gthp_PrincipalAmountOfPromissoryNote_lbl_d883f2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PrincipalAmountOfPromissoryNote_lbl_d883f2" xml:lang="en-US"> Principal amount of promissory note </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_IssuanceOfPromissoryNoteInExchangeOfRelatedPartyDebt" xlink:label="gthp_IssuanceOfPromissoryNoteInExchangeOfRelatedPartyDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_IssuanceOfPromissoryNoteInExchangeOfRelatedPartyDebt" xlink:to="gthp_IssuanceOfPromissoryNoteInExchangeOfRelatedPartyDebt_lbl_010f70" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_IssuanceOfPromissoryNoteInExchangeOfRelatedPartyDebt_lbl_010f70" xml:lang="en-US"> Issuance of promissory note in exchange of related party debt </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_LoansInterestBonusSalaryAndVacationPaidAmount" xlink:label="gthp_LoansInterestBonusSalaryAndVacationPaidAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_LoansInterestBonusSalaryAndVacationPaidAmount" xlink:to="gthp_LoansInterestBonusSalaryAndVacationPaidAmount_lbl_9bb376" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_LoansInterestBonusSalaryAndVacationPaidAmount_lbl_9bb376" xml:lang="en-US"> Loans, interest, bonus, salary and vacation paid amount </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_InterestRatePerAnnum" xlink:label="gthp_InterestRatePerAnnum"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_InterestRatePerAnnum" xlink:to="gthp_InterestRatePerAnnum_lbl_72f6d5" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_InterestRatePerAnnum_lbl_72f6d5" xml:lang="en-US"> Interest rate per annum </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InvestmentCompanyExpenseLimitationAgreementDescription" xlink:label="us-gaap_InvestmentCompanyExpenseLimitationAgreementDescription"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_InvestmentCompanyExpenseLimitationAgreementDescription" xlink:to="us-gaap_InvestmentCompanyExpenseLimitationAgreementDescription_lbl_f2661c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_InvestmentCompanyExpenseLimitationAgreementDescription_lbl_f2661c" xml:lang="en-US"> Description of exchange agreement </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AmountDuetoFormerEmployee" xlink:label="gthp_AmountDuetoFormerEmployee"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AmountDuetoFormerEmployee" xlink:to="gthp_AmountDuetoFormerEmployee_lbl_2625a6" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AmountDuetoFormerEmployee_lbl_2625a6" xml:lang="en-US"> Total amount due </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_MonthlyPaymentDue" xlink:label="gthp_MonthlyPaymentDue"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_MonthlyPaymentDue" xlink:to="gthp_MonthlyPaymentDue_lbl_c44fe7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_MonthlyPaymentDue_lbl_c44fe7" xml:lang="en-US"> Monthly payment due </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_OutstandingPrincipalLongtermDebt" xlink:to="gthp_OutstandingPrincipalLongtermDebt_lbl_f2bbad" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_OutstandingPrincipalLongtermDebt_lbl_f2bbad" xml:lang="en-US"> Outstanding principal balance </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_OutstandingPrincipalLongtermDebt" xlink:label="gthp_OutstandingPrincipalLongtermDebt"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_OutstandingPrincipalLongtermDebt" xlink:to="gthp_OutstandingPrincipalLongtermDebt_lbl_27" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_OutstandingPrincipalLongtermDebt_lbl_27" xml:lang="en-US"> [Outstanding principal balance] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccruedInterest" xlink:to="gthp_AccruedInterest_lbl_b5fee0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_AccruedInterest_lbl_b5fee0" xml:lang="en-US"> Accrued interest </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_AccruedInterest" xlink:label="gthp_AccruedInterest"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_AccruedInterest" xlink:to="gthp_AccruedInterest_lbl_28" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_AccruedInterest_lbl_28" xml:lang="en-US"> [Accrued interest] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FinancialInstrumentAxis" xlink:label="us-gaap_FinancialInstrumentAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_FinancialInstrumentAxis" xlink:to="us-gaap_FinancialInstrumentAxis_lbl_8b8d89" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_FinancialInstrumentAxis_lbl_8b8d89" xml:lang="en-US"> Financial Instrument Axis </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShortTermDebtTypeAxis" xlink:label="us-gaap_ShortTermDebtTypeAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ShortTermDebtTypeAxis" xlink:to="us-gaap_ShortTermDebtTypeAxis_lbl_d76f99" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ShortTermDebtTypeAxis_lbl_d76f99" xml:lang="en-US"> Short Term Debt Type Axis </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_WarrantsMember" xlink:to="gthp_WarrantsMember_lbl_47c994" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="gthp_WarrantsMember_lbl_47c994" xml:lang="en-US"> Warrants [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockOptionMember" xlink:label="us-gaap_StockOptionMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_StockOptionMember" xlink:to="us-gaap_StockOptionMember_lbl_125589" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_StockOptionMember_lbl_125589" xml:lang="en-US"> Stock Option [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_PreferredStocksMember" xlink:label="gthp_PreferredStocksMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_PreferredStocksMember" xlink:to="gthp_PreferredStocksMember_lbl_b9c945" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_PreferredStocksMember_lbl_b9c945" xml:lang="en-US"> Preferred Stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConvertibleDebtMember" xlink:label="us-gaap_ConvertibleDebtMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ConvertibleDebtMember" xlink:to="us-gaap_ConvertibleDebtMember_lbl_6e9f64" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ConvertibleDebtMember_lbl_6e9f64" xml:lang="en-US"> Convertible Debt [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="gthp-20230930.xsd#gthp_DilutiveInstrumentsMember" xlink:label="gthp_DilutiveInstrumentsMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="gthp_DilutiveInstrumentsMember" xlink:to="gthp_DilutiveInstrumentsMember_lbl_2d6fbc" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="gthp_DilutiveInstrumentsMember_lbl_2d6fbc" xml:lang="en-US"> Total Dilutive instruments [Member] </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProfitLoss" xlink:to="us-gaap_ProfitLoss_lbl_f0f1e9" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="us-gaap_ProfitLoss_lbl_f0f1e9" xml:lang="en-US"> Net loss </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProfitLoss" xlink:label="us-gaap_ProfitLoss"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ProfitLoss" xlink:to="us-gaap_ProfitLoss_lbl_2" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_ProfitLoss_lbl_2" xml:lang="en-US"> [Net Income (Loss), Including Portion Attributable to Noncontrolling Interest] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberBasicSharesOutstandingAdjustmentProForma" xlink:label="us-gaap_WeightedAverageNumberBasicSharesOutstandingAdjustmentProForma"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberBasicSharesOutstandingAdjustmentProForma" xlink:to="us-gaap_WeightedAverageNumberBasicSharesOutstandingAdjustmentProForma_lbl_9c29d7" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberBasicSharesOutstandingAdjustmentProForma_lbl_9c29d7" xml:lang="en-US"> Basic weighted average number of shares outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic" xlink:label="us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic" xlink:to="us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic_lbl_95c4d0" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic_lbl_95c4d0" xml:lang="en-US"> Net loss per share (basic) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:label="us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:to="us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_lbl_709536" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_lbl_709536" xml:lang="en-US"> Diluted weighted average number of shares outstanding </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="us-gaap_IncomeLossFromContinuingOperationsPerBasicShare"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:to="us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_lbl_9de194" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_lbl_9de194" xml:lang="en-US"> Net loss per share (diluted) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DilutiveSecuritiesAbstract" xlink:label="us-gaap_DilutiveSecuritiesAbstract"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_DilutiveSecuritiesAbstract" xlink:to="us-gaap_DilutiveSecuritiesAbstract_lbl_7dee7c" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_DilutiveSecuritiesAbstract_lbl_7dee7c" xml:lang="en-US"> Dilutive equity instruments (number of equivalent units): </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:to="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_lbl_d38d55" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_lbl_d38d55" xml:lang="en-US"> Dilutive equity instruments (number of equivalent units) </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="us-gaap_SubsequentEventTypeAxis"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SubsequentEventTypeAxis" xlink:to="us-gaap_SubsequentEventTypeAxis_lbl_c9d45a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SubsequentEventTypeAxis_lbl_c9d45a" xml:lang="en-US"> Subsequent Event Type [Axis] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SubsequentEventMember" xlink:label="us-gaap_SubsequentEventMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SubsequentEventMember" xlink:to="us-gaap_SubsequentEventMember_lbl_381b20" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SubsequentEventMember_lbl_381b20" xml:lang="en-US"> Subsequent Event [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SeriesDPreferredStockMember" xlink:label="us-gaap_SeriesDPreferredStockMember"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_SeriesDPreferredStockMember" xlink:to="us-gaap_SeriesDPreferredStockMember_lbl_1ce84e" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_SeriesDPreferredStockMember_lbl_1ce84e" xml:lang="en-US"> Series D Preferred Stock [Member] </link:label>
<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PreferredStockDividendsShares" xlink:label="us-gaap_PreferredStockDividendsShares"/>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockDividendsShares" xlink:to="us-gaap_PreferredStockDividendsShares_lbl_eefb0a" xlink:type="arc"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="us-gaap_PreferredStockDividendsShares_lbl_eefb0a" xml:lang="en-US"> Issued common shares for Preferred dividends </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:type="arc" xlink:from="gthp_PreferredStockLiquidationPreferences" xlink:to="gthp_PreferredStockLiquidationPreferences_d"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xml:lang="en-US" xlink:label="gthp_PreferredStockLiquidationPreferences_d"> The per share liquidation preference (or restrictions) of nonredeemable preferred stock (or preferred stock redeemable solely at the option of the issuer) that has a preference in involuntary liquidation considerably in excess of the par or stated value o </link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:type="arc" xlink:from="gthp_GainFromForgivenessOfDebt" xlink:to="gthp_GainFromForgivenessOfDebt_d"/>
<link:label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xml:lang="en-US" xlink:label="gthp_GainFromForgivenessOfDebt_d"> Difference between the fair value of payments made and the carrying amount of debt which is extinguished prior to maturity. </link:label>
</link:labelLink>
</link:linkbase>

8 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/30/22  Guided Therapeutics Inc.          10-K       12/31/21  100:10M                                    Discount Edgar/FA
 1/07/22  Guided Therapeutics Inc.          8-K:3,5,9   1/06/22   13:147K                                   Blueprint/FA
 6/10/21  Guided Therapeutics Inc.          8-K:1,3,5,9 6/10/21    3:132K                                   EDGARdocs/FA
 4/07/21  Guided Therapeutics Inc.          10-K       12/31/20  100:8.7M                                   Blueprint/FA
 4/20/20  Guided Therapeutics Inc.          10-K       12/31/19  117:13M                                    Blueprint/FA
11/15/18  Guided Therapeutics Inc.          8-K:5,9    11/14/18    2:36K                                    EDGARdocs/FA
 3/15/16  Guided Therapeutics Inc.          10-K       12/31/15   58:3.4M                                   EDGARdocs/FA
 3/23/12  Guided Therapeutics Inc.          8-K:5,9    12/31/11    2:105K                                   Issuer Direct/FA
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