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Cryoport, Inc. – ‘10-K’ for 12/31/22 – ‘EX-101.SCH’

On:  Tuesday, 2/28/23, at 5:08pm ET   ·   For:  12/31/22   ·   Accession #:  1410578-23-188   ·   File #:  1-34632

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  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 2/28/23  Cryoport, Inc.                    10-K       12/31/22  119:18M                                    Toppan Merrill/FA2

Annual Report   —   Form 10-K

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   3.97M 
 2: EX-21       Subsidiaries List                                   HTML     37K 
 3: EX-23.1     Consent of Expert or Counsel                        HTML     34K 
 4: EX-31.1     Certification -- §302 - SOA'02                      HTML     37K 
 5: EX-31.2     Certification -- §302 - SOA'02                      HTML     37K 
 6: EX-32.1     Certification -- §906 - SOA'02                      HTML     33K 
 7: EX-32.2     Certification -- §906 - SOA'02                      HTML     33K 
13: R1          Document and Entity Information                     HTML    100K 
14: R2          Consolidated Balance Sheets                         HTML    154K 
15: R3          Consolidated Balance Sheets (Parenthetical)         HTML     62K 
16: R4          Consolidated Statements of Operations               HTML    131K 
17: R5          Consolidated Statements of Comprehensive Loss       HTML     61K 
18: R6          Consolidated Statements of Stockholders' Equity     HTML    154K 
19: R7          Consolidated Statements of Stockholders' Equity     HTML     37K 
                (Parenthetical)                                                  
20: R8          Consolidated Statements of Cash Flows               HTML    174K 
21: R9          Nature of the Business                              HTML     36K 
22: R10         Summary of Significant Accounting Policies          HTML    165K 
23: R11         Acquisitions                                        HTML    138K 
24: R12         Cash, Cash Equivalents and Short-Term Investments   HTML    160K 
25: R13         Fair Value Measurements                             HTML    156K 
26: R14         Inventory                                           HTML     44K 
27: R15         Property and Equipment                              HTML     71K 
28: R16         Goodwill and Intangible Assets                      HTML    141K 
29: R17         Accrued Compensation and Related Expenses           HTML     44K 
30: R18         Convertible Senior Notes                            HTML     88K 
31: R19         Notes Payable                                       HTML     69K 
32: R20         Leases                                              HTML    122K 
33: R21         Employee Benefit Plans                              HTML     39K 
34: R22         Commitments and Contingencies                       HTML     41K 
35: R23         Stockholders' Equity                                HTML     65K 
36: R24         Stock-Based Compensation                            HTML    220K 
37: R25         Income Taxes                                        HTML    190K 
38: R26         Quarterly Financial Data                            HTML     99K 
39: R27         Summary of Significant Accounting Policies          HTML    241K 
                (Policies)                                                       
40: R28         Summary of Significant Accounting Policies          HTML    105K 
                (Tables)                                                         
41: R29         Acquisitions (Tables)                               HTML    128K 
42: R30         Cash, Cash Equivalents and Short-Term Investments   HTML    164K 
                (Tables)                                                         
43: R31         Fair Value Measurements (Tables)                    HTML    154K 
44: R32         Inventory (Tables)                                  HTML     45K 
45: R33         Property and Equipment (Tables)                     HTML     72K 
46: R34         Goodwill and Intangible Assets (Tables)             HTML    148K 
47: R35         Accrued Compensation and Related Expenses (Tables)  HTML     43K 
48: R36         Convertible Senior Notes (Tables)                   HTML     61K 
49: R37         Notes Payable (Tables)                              HTML     71K 
50: R38         Leases (Tables)                                     HTML    125K 
51: R39         Stockholders' Equity (Tables)                       HTML     39K 
52: R40         Stock-Based Compensation (Tables)                   HTML    226K 
53: R41         Income Taxes (Tables)                               HTML    190K 
54: R42         Quarterly Financial Data (Tables)                   HTML     98K 
55: R43         Summary of Significant Accounting Policies -        HTML     55K 
                Disaggregates Our Revenues by Major Source                       
                (Details)                                                        
56: R44         Summary of Significant Accounting Policies -        HTML     52K 
                Disaggregation Our Geographical Revenues by Origin               
                (Details)                                                        
57: R45         Summary of Significant Accounting Policies - Basic  HTML     75K 
                and Diluted Net Loss Per Share (Details)                         
58: R46         Summary of Significant Accounting Policies -        HTML     44K 
                Antidilutive shares (Details)                                    
59: R47         Summary of Significant Accounting Policies -        HTML    170K 
                Additional information (Details)                                 
60: R48         Acquisition - Additional information (Details)      HTML    115K 
61: R49         Acquisitions - Allocation of purchase price         HTML    104K 
                (Details)                                                        
62: R50         Acquisition - Preliminary Fair Value of Intangible  HTML     76K 
                Assets (Details)                                                 
63: R51         Cash, Cash Equivalents and Short-Term Investments   HTML     58K 
                (Details)                                                        
64: R52         Cash, Cash Equivalents and Short-Term Investments   HTML     44K 
                - Available-for-sale Investments (Details)                       
65: R53         Cash, Cash Equivalents and Short-term Investments   HTML     52K 
                - Contractual Maturities (Details)                               
66: R54         Cash, Cash Equivalents and Short-Term Investments   HTML     57K 
                - Company's gross unrealized losses and fair value               
                (Details)                                                        
67: R55         Cash, Cash Equivalents and Short-Term Investments   HTML     41K 
                - Equity Investments (Details)                                   
68: R56         Fair Value Measurements - Fair value hierarchy      HTML     64K 
                (Details)                                                        
69: R57         Fair Value Measurements - Estimated fair values     HTML     40K 
                and the carrying values (Details)                                
70: R58         Fair Value Measurements - losses recognized in      HTML     50K 
                earnings and the change in net asset - (Details)                 
71: R59         Fair Value Measurements - Additional Information    HTML     38K 
                (Details)                                                        
72: R60         Inventory (Details)                                 HTML     39K 
73: R61         Property and Equipment (Details)                    HTML     59K 
74: R62         Property and Equipment - Geographic information     HTML     38K 
                (Details)                                                        
75: R63         Property and Equipment - Additional information     HTML     38K 
                (Details)                                                        
76: R64         Goodwill and Intangible Assets - Schedule of        HTML     51K 
                goodwill (Details)                                               
77: R65         Goodwill and Intangible Assets - Intangible Assets  HTML     66K 
                (Details)                                                        
78: R66         Goodwill and Intangible Assets - Expected future    HTML     46K 
                amortization (Details)                                           
79: R67         Goodwill and Intangible Assets - Additional         HTML     34K 
                Information (Details)                                            
80: R68         Accrued Compensation and Related Expenses           HTML     38K 
                (Details)                                                        
81: R69         Convertible Senior Notes - Components of            HTML     43K 
                Convertible notes payable (Details)                              
82: R70         Convertible Senior Notes - Interest expenses        HTML     40K 
                incurred on Convertible notes payable (Details)                  
83: R71         Convertible Senior Notes - Additional information   HTML    118K 
                (Details)                                                        
84: R72         Notes Payable (Details)                             HTML     53K 
85: R73         Notes Payable - Interest expense (Details)          HTML     43K 
86: R74         Notes Payable - Future note payments (Details)      HTML     52K 
87: R75         Note Payable - Additional information (Details)     HTML     54K 
88: R76         Leases - Components Of Lease Cost (Details)         HTML     44K 
89: R77         Leases - Supplemental Cash Flows Information        HTML     58K 
                (Details)                                                        
90: R78         Leases - Future Payments Under Non-Cancellable      HTML     74K 
                Leases (Details)                                                 
91: R79         Leases - Additional Information (Details)           HTML     44K 
92: R80         Employee Benefit Plans (Details)                    HTML     46K 
93: R81         Commitments and Contingencies (Details)             HTML     38K 
94: R82         Stockholders' Equity - Authorized Stock (Details)   HTML     50K 
95: R83         Stockholders' Equity - Common Stock Issuances For   HTML     39K 
                Services (Details)                                               
96: R84         Stockholders' Equity - Repurchase Program           HTML     40K 
                (Details)                                                        
97: R85         Stockholders' Equity - November 2021 Registered     HTML     49K 
                Direct Placement and Stock Purchase Agreements                   
                (Details)                                                        
98: R86         Stockholders' Equity - January 2021 Public          HTML     42K 
                Offering (Details)                                               
99: R87         Stockholders' Equity - Blackstone Private           HTML    115K 
                Placement and Conversion (Details)                               
100: R88         Stockholders' Equity - Common Stock Reserved for    HTML     47K  
                Future Issuance (Details)                                        
101: R89         Stock-Based Compensation - Assumptions Used to      HTML     49K  
                Estimate Fair Value of Stock Options (Details)                   
102: R90         Stock-Based Compensation - Stock-based              HTML     40K  
                Compensation Expense (Details)                                   
103: R91         Stock-Based Compensation - Stock Option Activity    HTML    101K  
                (Details)                                                        
104: R92         Stock-Based Compensation - Schedule of Stock        HTML     83K  
                Options Outstanding and Exercisable (Details)                    
105: R93         Stock-Based Compensation - Restricted stock unit    HTML     55K  
                (Details)                                                        
106: R94         Stock-Based Compensation - Additional Information   HTML     74K  
                (Details)                                                        
107: R95         Income Taxes - Loss Before Provision For Income     HTML     38K  
                Taxes (Details)                                                  
108: R96         Income Taxes - Expense For Income Taxes (Details)   HTML     61K  
109: R97         Income Taxes - Schedule of Deferred Tax Assets      HTML     72K  
                (Details)                                                        
110: R98         Income Taxes - net deferred tax liability as        HTML     39K  
                presented in consolidated balance sheet (Details)                
111: R99         Income Taxes - Schedule of Income Tax Provision     HTML     63K  
                (Details)                                                        
112: R100        Income Taxes - Schedule of unrecognized tax         HTML     41K  
                positions (Details)                                              
113: R101        Income Taxes - Additional information (Details)     HTML     47K  
114: R102        Quarterly Financial Data (Details)                  HTML     73K  
117: XML         IDEA XML File -- Filing Summary                      XML    224K  
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116: EXCEL       IDEA Workbook of Financial Reports                  XLSX    262K  
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10: EX-101.DEF  XBRL Definitions -- cyrx-20221231_def                XML   1.05M 
11: EX-101.LAB  XBRL Labels -- cyrx-20221231_lab                     XML   2.26M 
12: EX-101.PRE  XBRL Presentations -- cyrx-20221231_pre              XML   1.63M 
 8: EX-101.SCH  XBRL Schema -- cyrx-20221231                         XSD    287K 
118: JSON        XBRL Instance as JSON Data -- MetaLinks              667±  1.08M  
119: ZIP         XBRL Zipped Folder -- 0001410578-23-000188-xbrl      Zip    989K

‘EX-101.SCH’   —   XBRL Schema — cyrx-20221231

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<xsd:element name="ScheduleOfInterestExpensesOnConvertibleNotesPayableTableTextBlock" id="cyrx_ScheduleOfInterestExpensesOnConvertibleNotesPayableTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="ScenarioOneMember" id="cyrx_ScenarioOneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="ScenarioTwoMember" id="cyrx_ScenarioTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="ThirdPartyOfferingRelatedCosts" id="cyrx_ThirdPartyOfferingRelatedCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="DebtInstrumentRedemptionThresholdTradingDays" id="cyrx_DebtInstrumentRedemptionThresholdTradingDays" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="DebtInstrumentRegistrationDefaultAdditionalInterestRate" id="cyrx_DebtInstrumentRegistrationDefaultAdditionalInterestRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="DebtInstrumentRegistrationDefaultThresholdMaximumCombinedInterestRate" id="cyrx_DebtInstrumentRegistrationDefaultThresholdMaximumCombinedInterestRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="DebtInstrumentRegistrationDefaultCashPaymentToEachNoteholderPercentage" id="cyrx_DebtInstrumentRegistrationDefaultCashPaymentToEachNoteholderPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="ConvertibleSeniorNotesMember" id="cyrx_ConvertibleSeniorNotesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="InterestAmountOnAccountsPayableAndAccruedLiabilities" id="cyrx_InterestAmountOnAccountsPayableAndAccruedLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="ClassCConvertiblePreferredStockMember" id="cyrx_ClassCConvertiblePreferredStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="MveCryobiologicalStorageBusinessMember" id="cyrx_MveCryobiologicalStorageBusinessMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="CryopdpMember" id="cyrx_CryopdpMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockRedemptionPeriodAxis" id="cyrx_PreferredStockRedemptionPeriodAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockRedemptionPeriodDomain" id="cyrx_PreferredStockRedemptionPeriodDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockRedemptionPeriodOneMember" id="cyrx_PreferredStockRedemptionPeriodOneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockRedemptionPeriodTwoMember" id="cyrx_PreferredStockRedemptionPeriodTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockRedemptionPeriodThreeMember" id="cyrx_PreferredStockRedemptionPeriodThreeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="ReimbursementOfTransactionalExpenses" id="cyrx_ReimbursementOfTransactionalExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/>
<xsd:element name="NetProceedsFromIssuanceOfPrivatePlacement" id="cyrx_NetProceedsFromIssuanceOfPrivatePlacement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockConvertibleConversionPricePerShare" id="cyrx_PreferredStockConvertibleConversionPricePerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockConvertibleConversionRate" id="cyrx_PreferredStockConvertibleConversionRate" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockConvertibleThresholdTradingDays" id="cyrx_PreferredStockConvertibleThresholdTradingDays" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockConvertibleThresholdConsecutiveTradingDays" id="cyrx_PreferredStockConvertibleThresholdConsecutiveTradingDays" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockConvertibleStockPriceTriggerPercentage" id="cyrx_PreferredStockConvertibleStockPriceTriggerPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="DeemedDividend" id="cyrx_DeemedDividend" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockSharesToBeRedeemed" id="cyrx_PreferredStockSharesToBeRedeemed" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockRedemptionPricePercentage" id="cyrx_PreferredStockRedemptionPricePercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockIfNotRepurchasedDividendRatePercentage" id="cyrx_PreferredStockIfNotRepurchasedDividendRatePercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="NumberOfBoardMemberWhoCanBeElectedByPreferredStockHolders" id="cyrx_NumberOfBoardMemberWhoCanBeElectedByPreferredStockHolders" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredStockOwnershipPercentageToExerciseRightToNominateBoard" id="cyrx_PreferredStockOwnershipPercentageToExerciseRightToNominateBoard" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="PreferredClassCMember" id="cyrx_PreferredClassCMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="FreezerMember" id="cyrx_FreezerMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="TruckAndAutoMember" id="cyrx_TruckAndAutoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="NumberOfInstallments" id="cyrx_NumberOfInstallments" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="NotesPayableTextBlock" id="cyrx_NotesPayableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="AgentNetworkMember" id="cyrx_AgentNetworkMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="DeemedDividendOnSeriesCConvertiblePreferredStockValue" id="cyrx_DeemedDividendOnSeriesCConvertiblePreferredStockValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="PaidInKindDividendOnSeriesCConvertiblePreferredStockValue" id="cyrx_PaidInKindDividendOnSeriesCConvertiblePreferredStockValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="UsEmployeesMember" id="cyrx_UsEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="NonUsEmployeesMember" id="cyrx_NonUsEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseRightOfUseAssets" id="cyrx_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseRightOfUseAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="instant"/>
<xsd:element name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOperatingLeaseLiabilities" id="cyrx_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOperatingLeaseLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="instant"/>
<xsd:element name="PaidInKindDividendOnSeriesCConvertiblePreferredStocksValue" id="cyrx_PaidInKindDividendOnSeriesCConvertiblePreferredStocksValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="RangeEightMember" id="cyrx_RangeEightMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="BusinessCombinationsAcquisitionCostsPolicyPolicyTextBlock" id="cyrx_BusinessCombinationsAcquisitionCostsPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccruedCompensationAndRelatedExpenses" id="cyrx_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccruedCompensationAndRelatedExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="instant"/>
<xsd:element name="EffectiveIncomeTaxRateReconciliationTransactionCosts" id="cyrx_EffectiveIncomeTaxRateReconciliationTransactionCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="EffectiveIncomeTaxRateReconciliationExecutiveCompensationAmount" id="cyrx_EffectiveIncomeTaxRateReconciliationExecutiveCompensationAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="EffectiveIncomeTaxRateReconciliationContingencies" id="cyrx_EffectiveIncomeTaxRateReconciliationContingencies" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="AdjustmentsToAdditionalPaidInCapitalPaidInKindDividends" id="cyrx_AdjustmentsToAdditionalPaidInCapitalPaidInKindDividends" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/>
<xsd:element name="StatutoryCreditUsageLimitForResearchAndDevelopmentForTaxRelief" id="cyrx_StatutoryCreditUsageLimitForResearchAndDevelopmentForTaxRelief" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/>
<xsd:element name="DeferredIncomeTaxExpenseBenefitTotal" id="cyrx_DeferredIncomeTaxExpenseBenefitTotal" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="DeferredIncomeTaxLiabilitiesNetMember" id="cyrx_DeferredIncomeTaxLiabilitiesNetMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="AdjustmentsToAdditionalPaidInCapitalConversionCosts" id="cyrx_AdjustmentsToAdditionalPaidInCapitalConversionCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/>
<xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsIssuedInPeriod" id="cyrx_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsIssuedInPeriod" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="WorkingCapital" id="cyrx_WorkingCapital" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="Adjustments" id="cyrx_Adjustments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="CriticalTransportSolutionsAustraliaAndFairgateMember" id="cyrx_CriticalTransportSolutionsAustraliaAndFairgateMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorizedButUnissued" id="cyrx_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorizedButUnissued" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="CustomerMember" id="cyrx_CustomerMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="WarrantsExercisedIntrinsicValue" id="cyrx_WarrantsExercisedIntrinsicValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/>
<xsd:element name="CostOfServicesRevenuesPolicyTextBlock" id="cyrx_CostOfServicesRevenuesPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="CostOfProductRevenuesPolicyTextBlock" id="cyrx_CostOfProductRevenuesPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="BusinessCombinationPriorPeriodAdjustmentDeferredTax" id="cyrx_BusinessCombinationPriorPeriodAdjustmentDeferredTax" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="BusinessCombinationPriorPeriodAdjustmentNotesPayable" id="cyrx_BusinessCombinationPriorPeriodAdjustmentNotesPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="ExecutiveCompensationLimit" id="cyrx_ExecutiveCompensationLimit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant"/>
<xsd:element name="SeniorNotes2025Member" id="cyrx_SeniorNotes2025Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="SeniorNotes2026Member" id="cyrx_SeniorNotes2026Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="LossOnExtinguishmentOfDebt" id="cyrx_LossOnExtinguishmentOfDebt" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="TotalRemainingPrincipalAmountOutstanding" id="cyrx_TotalRemainingPrincipalAmountOutstanding" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="IssuanceOfCommonStockInDirectPlacementNet" id="cyrx_IssuanceOfCommonStockInDirectPlacementNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/>
<xsd:element name="ExclusiveRightOfNoteholdersMaximumPercentageOfSpecialInterestOnPrincipalAmount" id="cyrx_ExclusiveRightOfNoteholdersMaximumPercentageOfSpecialInterestOnPrincipalAmount" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="ExclusiveRightOfNoteholdersMaximumNumberOfDaysToReceiveSpecialInterestOnSeniorNotes" id="cyrx_ExclusiveRightOfNoteholdersMaximumNumberOfDaysToReceiveSpecialInterestOnSeniorNotes" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="DebtInstrumentConvertibleConversionPrice" id="cyrx_DebtInstrumentConvertibleConversionPrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant"/>
<xsd:element name="DebtInstrumentConvertibleThresholdMaximumConversionRatio" id="cyrx_DebtInstrumentConvertibleThresholdMaximumConversionRatio" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="LeasesEquipmentUnderFinanceLeasesAmount" id="cyrx_LeasesEquipmentUnderFinanceLeasesAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant"/>
<xsd:element name="AccumulatedOtherComprehensiveIncomeLoss" id="cyrx_AccumulatedOtherComprehensiveIncomeLoss" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="instant"/>
<xsd:element name="IncomeTaxReconciliationNonDeductibleExpenseLossOnDebtExtinguishment" id="cyrx_IncomeTaxReconciliationNonDeductibleExpenseLossOnDebtExtinguishment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="EffectiveIncomeTaxRateReconciliationDeemedForeignDividendIncome" id="cyrx_EffectiveIncomeTaxRateReconciliationDeemedForeignDividendIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="ConcurrentPlacementMember" id="cyrx_ConcurrentPlacementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="DebtInstrumentRedemptionPrincipalAmountRedeemed" id="cyrx_DebtInstrumentRedemptionPrincipalAmountRedeemed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration"/>
<xsd:element name="NetProceedsAfterDeductingBankerFeesToBeUsedForGeneralCorporatePurposes" id="cyrx_NetProceedsAfterDeductingBankerFeesToBeUsedForGeneralCorporatePurposes" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration"/>
<xsd:element name="CellCoBioservicesMember" id="cyrx_CellCoBioservicesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration"/>
<xsd:element name="DeferredTaxLiabilitiesAbstract." id="cyrx_DeferredTaxLiabilitiesAbstract." type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="PurchaseOfEquipmentThroughCapitalLeaseObligation" id="cyrx_PurchaseOfEquipmentThroughCapitalLeaseObligation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="AdjustmentsToAdditionalPaidInCapitalDeemedDividend" id="cyrx_AdjustmentsToAdditionalPaidInCapitalDeemedDividend" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit"/>
<xsd:element name="BeneficialConversionFeatureOfSeriesCConvertiblePreferredStockValue" id="cyrx_BeneficialConversionFeatureOfSeriesCConvertiblePreferredStockValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="ScheduleOfInterestExpenseOnNotesPayableTableTextBlock" id="cyrx_ScheduleOfInterestExpenseOnNotesPayableTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="NotesPayableMember" id="cyrx_NotesPayableMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="NotesPayableMaturingOnJuly2027Member" id="cyrx_NotesPayableMaturingOnJuly2027Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="NotesPayableMaturingOnJuly2030Member" id="cyrx_NotesPayableMaturingOnJuly2030Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="PolarExpressMadridSpainMember" id="cyrx_PolarExpressMadridSpainMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="CellMattersBasedInLiegeBelgiumMember" id="cyrx_CellMattersBasedInLiegeBelgiumMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="BusinessCombinationConsiderationUpfrontFees" id="cyrx_BusinessCombinationConsiderationUpfrontFees" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="BusinessCombinationAcquisitionEquityInterestSharesIssuable" id="cyrx_BusinessCombinationAcquisitionEquityInterestSharesIssuable" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="ExcessAndObsoleteInventory" id="cyrx_ExcessAndObsoleteInventory" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="GainLossOnInsuranceSettlement" id="cyrx_GainLossOnInsuranceSettlement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit"/>
<xsd:element name="EstimatedRevenueImpactDueToCatastrophes" id="cyrx_EstimatedRevenueImpactDueToCatastrophes" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="ProceedsFromInsuranceSettlement" id="cyrx_ProceedsFromInsuranceSettlement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="GainLossOnInsuranceSettlementForReimbursementOfPropertyAndEquipment" id="cyrx_GainLossOnInsuranceSettlementForReimbursementOfPropertyAndEquipment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit"/>
<xsd:element name="GainLossOnInsuranceSettlementRelatedToBusinessInterruption" id="cyrx_GainLossOnInsuranceSettlementRelatedToBusinessInterruption" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit"/>
<xsd:element name="BusinessCombinationMeasurementPeriodAdjustments" id="cyrx_BusinessCombinationMeasurementPeriodAdjustments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit"/>
<xsd:element name="ContractWithCustomerLiabilityRevenueRecognizedExcludingOpeningBalance" id="cyrx_ContractWithCustomerLiabilityRevenueRecognizedExcludingOpeningBalance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit"/>
<xsd:element name="CashRepurchasePrice" id="cyrx_CashRepurchasePrice" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="RightOfUseAssetObtainedInExchangeForLeaseObligationsAbstract" id="cyrx_RightOfUseAssetObtainedInExchangeForLeaseObligationsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardWeightedAverageFairValuePerShares" id="cyrx_ShareBasedCompensationArrangementByShareBasedPaymentAwardWeightedAverageFairValuePerShares" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="ContingentConsiderationMember" id="cyrx_ContingentConsiderationMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="PeriodOfContingentConsiderationPayable" id="cyrx_PeriodOfContingentConsiderationPayable" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="MaximumContingentConsiderationPayableInCash" id="cyrx_MaximumContingentConsiderationPayableInCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit"/>
<xsd:element name="Acquisitions2021Member" id="cyrx_Acquisitions2021Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="Acquisitions2022Member" id="cyrx_Acquisitions2022Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="ResearchAndExperimentalExpendituresAndSoftwareDevelopmentCostsToCapitalAccount" id="cyrx_ResearchAndExperimentalExpendituresAndSoftwareDevelopmentCostsToCapitalAccount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit"/>
<xsd:element name="AmortizationForResearchAndExperimentalExpendituresAndSoftwareDevelopmentCosts" id="cyrx_AmortizationForResearchAndExperimentalExpendituresAndSoftwareDevelopmentCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="OperatingLeasesForCorporateOfficesAndCertainEquipment" id="cyrx_OperatingLeasesForCorporateOfficesAndCertainEquipment" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="LesseeOperatingLeaseAggregateRentalAmount" id="cyrx_LesseeOperatingLeaseAggregateRentalAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit"/>
<xsd:element name="LeaseAgreementForAdministrativeGlobalSupplyChainCenterAndResearchAndDevelopmentCenterInSantaAnaCaliforniaMember" id="cyrx_LeaseAgreementForAdministrativeGlobalSupplyChainCenterAndResearchAndDevelopmentCenterInSantaAnaCaliforniaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="RangeNineMember" id="cyrx_RangeNineMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true"/>
<xsd:element name="AvailableForSaleSecuritiesUnrealizedLossPositionFairValue" id="cyrx_AvailableForSaleSecuritiesUnrealizedLossPositionFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit"/>
<xsd:element name="AvailableForSaleSecuritiesUnrealizedLossPositionTwelveMonthsOrLongerFairValue" id="cyrx_AvailableForSaleSecuritiesUnrealizedLossPositionTwelveMonthsOrLongerFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit"/>
<xsd:element name="AvailableForSaleSecuritiesUnrealizedLossPositionLessThanTwelveMonthsFairValue" id="cyrx_AvailableForSaleSecuritiesUnrealizedLossPositionLessThanTwelveMonthsFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit"/>
<xsd:element name="IssuanceOfCommonStockInDirectPlacementNetInShare" id="cyrx_IssuanceOfCommonStockInDirectPlacementNetInShare" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="AdjustmentsToAdditionalPaidInConvertiblePreferredStock" id="cyrx_AdjustmentsToAdditionalPaidInConvertiblePreferredStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit"/>
<xsd:element name="IssuanceOfConvertiblePreferredStockInShares" id="cyrx_IssuanceOfConvertiblePreferredStockInShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
<xsd:element name="NumberOfStockIncentivePlans" id="cyrx_NumberOfStockIncentivePlans" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false"/>
</xsd:schema>

3 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

12/21/23  Cryoport, Inc.                    424B3                  1:533K                                   Toppan Merrill/FA
12/15/23  Cryoport, Inc.                    POS AM                 2:866K                                   Toppan Merrill/FA
12/15/23  Cryoport, Inc.                    POSASR     12/15/23    6:967K                                   Toppan Merrill/FA

24 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/21/22  Cryoport, Inc.                    8-K:5,9     3/15/22   12:430K                                   Toppan Merrill/FA
11/12/21  Cryoport, Inc.                    8-K:1,2,3,911/12/21   12:1.1M                                   Toppan Merrill/FA
 5/05/21  Cryoport, Inc.                    8-K:5,9     4/30/21   11:369K                                   Toppan Merrill/FA
 3/01/21  Cryoport, Inc.                    10-K       12/31/20  112:13M                                    Toppan Merrill/FA
10/01/20  Cryoport, Inc.                    8-K:1,2,3,510/01/20   15:1M                                     Toppan Merrill/FA
 8/25/20  Cryoport, Inc.                    8-K:1,3,7,9 8/24/20   15:3.7M                                   Toppan Merrill/FA
 8/21/20  Cryoport, Inc.                    8-K:1,7,9   8/21/20   13:706K                                   Toppan Merrill/FA
 5/27/20  Cryoport, Inc.                    8-K:1,2,3,9 5/26/20    3:806K                                   Toppan Merrill/FA
10/30/19  Cryoport, Inc.                    8-K:5,9    10/28/19    3:106K                                   Toppan Merrill/FA
 5/14/19  Cryoport, Inc.                    8-K:1,2,7,9 5/14/19    3:454K                                   Toppan Merrill/FA
 3/13/19  Cryoport, Inc.                    10-K       12/31/18   92:10M                                    Toppan Merrill/FA
 4/03/18  Cryoport, Inc.                    8-K:5,9     3/28/18    2:52K                                    Toppan Merrill/FA
 5/31/17  Cryoport, Inc.                    8-K:5,9     5/26/17    2:109K                                   Toppan Merrill/FA
 2/08/16  Cryoport, Inc.                    8-K:2,5,8,9 2/08/16    3:218K                                   Toppan Merrill/FA
12/01/15  Cryoport, Inc.                    8-K:5,9    11/23/15    2:334K                                   Toppan Merrill/FA
10/01/15  Cryoport, Inc.                    DEF 14A    10/28/15    1:491K                                   Toppan Merrill/FA
 9/04/15  Cryoport, Inc.                    8-K:3,5,9   9/01/15    3:1.5M                                   Toppan Merrill/FA
 6/22/15  Cryoport, Inc.                    S-1/A                  6:7.7M                                   Toppan Merrill/FA
 5/19/15  Cryoport, Inc.                    10-K        3/31/15   82:9.4M                                   Toppan Merrill/FA
 4/17/15  Cryoport, Inc.                    S-1/A                 84:12M                                    Toppan Merrill/FA
 3/30/15  Cryoport, Inc.                    8-K:3,5,9   3/26/15    2:452K                                   Toppan Merrill/FA
 2/20/15  Cryoport, Inc.                    8-K:1,2,3,5 2/17/15    4:217K                                   Toppan Merrill/FA
11/09/12  Cryoport, Inc.                    10-Q        9/30/12   47:3.4M                                   Donnelley … Solutions/FA
 8/15/11  Cryoport, Inc.                    DEF 14A     9/22/11    1:314K                                   Donnelley … Solutions/FA
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