SEC Info℠  
    Home      Search      My Interests      Help      Sign In      Please Sign In

Angiodynamics Inc – ‘10-Q’ for 8/31/15 – ‘EX-101.DEF’

On:  Thursday, 10/8/15, at 4:36pm ET   ·   For:  8/31/15   ·   Accession #:  1275187-15-22   ·   File #:  0-50761

Previous ‘10-Q’:  ‘10-Q’ on 4/9/15 for 2/28/15   ·   Next:  ‘10-Q’ on 1/8/16 for 11/30/15   ·   Latest:  ‘10-Q’ on 4/9/24 for 2/29/24

Find Words in Filings emoji
 		  in    Show  and   ↓Hints

  As Of               Filer                 Filing    For·On·As Docs:Size

10/08/15  Angiodynamics Inc                 10-Q        8/31/15   69:5.1M

Quarterly Report   —   Form 10-Q   —   Sect. 13 / 15(d) – SEA’34
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-Q        Quarterly Report                                    HTML    371K 
 2: EX-31.1     Certification -- §302 - SOA'02                      HTML     26K 
 3: EX-31.2     Certification -- §302 - SOA'02                      HTML     26K 
 4: EX-32.1     Certification -- §906 - SOA'02                      HTML     21K 
 5: EX-32.2     Certification -- §906 - SOA'02                      HTML     21K 
46: R1          Document and Entity Information                     HTML     41K 
36: R2          Consolidated Statements of Income                   HTML     89K 
44: R3          Consolidated Statements of Comprehensive Income     HTML     50K 
48: R4          Consolidated Balance Sheets                         HTML    127K 
63: R5          Consolidated Balance Sheets (Parenthetical)         HTML     47K 
38: R6          Consolidated Statements of Cash Flows               HTML    103K 
43: R7          Consolidated Statement of Stockholders' Equity      HTML     70K 
32: R8          Consolidated Financial Statements                   HTML     30K 
25: R9          Inventories                                         HTML     32K 
64: R10         Goodwill and Intangible Assets                      HTML     75K 
50: R11         Accrued Liabilities                                 HTML     38K 
49: R12         Long Term Debt                                      HTML     30K 
54: R13         Income Taxes                                        HTML     59K 
55: R14         Share-Based Compensation                            HTML     30K 
53: R15         Earnings Per Share                                  HTML     33K 
56: R16         Segment and Geographic Information                  HTML     49K 
45: R17         Fair Value                                          HTML    138K 
47: R18         Marketable Securities                               HTML     53K 
52: R19         Commitments and Contingencies                       HTML     35K 
69: R20         Recently Issued Accounting Pronouncements           HTML     32K 
59: R21         Restructuring                                       HTML     24K 
40: R22         Inventories (Tables)                                HTML     31K 
51: R23         Goodwill and Intangible Assets (Tables)             HTML     70K 
42: R24         Accrued Liabilities (Tables)                        HTML     37K 
19: R25         Income Taxes (Tables)                               HTML     54K 
60: R26         Earnings Per Share (Tables)                         HTML     31K 
65: R27         Segment and Geographic Information (Tables)         HTML     44K 
28: R28         Fair Value (Tables)                                 HTML    131K 
27: R29         Marketable Securities (Tables)                      HTML     46K 
30: R30         Consolidated Financial Statements - Additional      HTML     70K 
                Information (Detail)                                             
31: R31         Acquisitions - Additional Information (Detail)      HTML     36K 
33: R32         Inventories - Schedule of Inventories (Detail)      HTML     30K 
18: R33         Goodwill and Intangible Assets - Additional         HTML     25K 
                Information (Detail)                                             
57: R34         Goodwill and Intangible Assets - Goodwill by        HTML     22K 
                Segment (Detail)                                                 
39: R35         Goodwill and Intangible Assets - Intangible Assets  HTML     57K 
                (Detail)                                                         
41: R36         Accrued Liabilities - Summary of Accrued            HTML     52K 
                Liabilities (Detail)                                             
22: R37         Long Term Debt - Additional Information (Detail)    HTML     77K 
68: R38         Income Taxes - Components of Income Tax             HTML     40K 
                Expense/(Benefit) (Detail)                                       
12: R39         Income Taxes - Additional Information (Detail)      HTML     31K 
34: R40         Income Taxes Net Operating Loss Carryforwards       HTML     45K 
                (Details)                                                        
62: R41         Share-Based Compensation (Details)                  HTML     29K 
21: R42         Earnings Per Share - Reconciliation of Basic to     HTML     28K 
                Diluted Weighted-Average Shares Outstanding                      
                (Detail)                                                         
26: R43         Segment and Geographic Information - Additional     HTML     22K 
                Information (Detail)                                             
29: R44         Segment and Geographic Information - Summary of     HTML     31K 
                Net Sales by Product Category (Detail)                           
37: R45         Segment and Geographic Information - Summary of     HTML     31K 
                Net Sales by Geographic Area (Detail)                            
17: R46         Fair Value - Additional Information (Detail)        HTML     21K 
24: R47         Fair Value - Fair Value of Assets and Liabilities   HTML     67K 
                Measured on a Recurring Basis (Detail)                           
14: R48         Fair Value - Fair Value Measurements Using          HTML     41K 
                Significant Unobservable Inputs (Detail)                         
61: R49         Fair Value - Summary Showing the Recurring Fair     HTML     53K 
                Value Measurements of the Contingent Consideration               
                Liability (Detail)                                               
20: R50         Fair Value - Summary Showing Reconciliation of the  HTML     25K 
                Contingent Payments (Detail)                                     
58: R51         Marketable Securities - Additional Information      HTML     23K 
                (Detail)                                                         
23: R52         Marketable Securities - Marketable Securities       HTML     34K 
                (Detail)                                                         
35: R53         Commitments and Continfencies - Additional          HTML     35K 
                Information (Detail)                                             
13: R54         Restructuring - Additional Information (Detail)     HTML     26K 
16: R55         Immaterial Corrections (Details)                    HTML    111K 
67: XML         IDEA XML File -- Filing Summary                      XML    120K 
15: EXCEL       IDEA Workbook of Financial Reports                  XLSX     63K 
 6: EX-101.INS  XBRL Instance -- ango-20150831                       XML   1.26M 
 8: EX-101.CAL  XBRL Calculations -- ango-20150831_cal               XML    187K 
 9: EX-101.DEF  XBRL Definitions -- ango-20150831_def                XML    507K 
10: EX-101.LAB  XBRL Labels -- ango-20150831_lab                     XML   1.25M 
11: EX-101.PRE  XBRL Presentations -- ango-20150831_pre              XML    786K 
 7: EX-101.SCH  XBRL Schema -- ango-20150831                         XSD    144K 
66: ZIP         XBRL Zipped Folder -- 0001275187-15-000022-xbrl      Zip    167K

‘EX-101.DEF’   —   XBRL Definitions — ango-20150831_def

This Exhibit is an XBRL XML File.

                                                                                                                                                                                
<?xml version="1.0" encoding="windows-1252"?>
<!-- XBRL Document Created with Wdesk from Workiva -->
<!-- -->
<linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<roleRef roleURI="http://www.angiodynamics.com/role/AccruedLiabilities" xlink:href="ango-20150831.xsd#AccruedLiabilities" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/AccruedLiabilitiesSummaryOfAccruedLiabilitiesDetail" xlink:href="ango-20150831.xsd#AccruedLiabilitiesSummaryOfAccruedLiabilitiesDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/AccruedLiabilitiesTables" xlink:href="ango-20150831.xsd#AccruedLiabilitiesTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/Acquisitions" xlink:href="ango-20150831.xsd#Acquisitions" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/AcquisitionsAdditionalInformationDetail" xlink:href="ango-20150831.xsd#AcquisitionsAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/CommitmentsAndContinfenciesAdditionalInformationDetail" xlink:href="ango-20150831.xsd#CommitmentsAndContinfenciesAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/CommitmentsAndContingencies" xlink:href="ango-20150831.xsd#CommitmentsAndContingencies" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedBalanceSheets" xlink:href="ango-20150831.xsd#ConsolidatedBalanceSheets" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:href="ango-20150831.xsd#ConsolidatedBalanceSheetsParenthetical" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedFinancialStatements" xlink:href="ango-20150831.xsd#ConsolidatedFinancialStatements" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedFinancialStatementsAdditionalInformationDetail" xlink:href="ango-20150831.xsd#ConsolidatedFinancialStatementsAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedStatementOfStockholdersEquity" xlink:href="ango-20150831.xsd#ConsolidatedStatementOfStockholdersEquity" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedStatementsOfCashFlows" xlink:href="ango-20150831.xsd#ConsolidatedStatementsOfCashFlows" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedStatementsOfComprehensiveIncome" xlink:href="ango-20150831.xsd#ConsolidatedStatementsOfComprehensiveIncome" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ConsolidatedStatementsOfIncome" xlink:href="ango-20150831.xsd#ConsolidatedStatementsOfIncome" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/DocumentAndEntityInformation" xlink:href="ango-20150831.xsd#DocumentAndEntityInformation" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/EarningsPerShare" xlink:href="ango-20150831.xsd#EarningsPerShare" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/EarningsPerShareAdditionalInformationDetail" xlink:href="ango-20150831.xsd#EarningsPerShareAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/EarningsPerShareReconciliationOfBasicToDilutedWeightedAverageSharesOutstandingDetail" xlink:href="ango-20150831.xsd#EarningsPerShareReconciliationOfBasicToDilutedWeightedAverageSharesOutstandingDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/EarningsPerShareTables" xlink:href="ango-20150831.xsd#EarningsPerShareTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/FairValue" xlink:href="ango-20150831.xsd#FairValue" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/FairValueAdditionalInformationDetail" xlink:href="ango-20150831.xsd#FairValueAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/FairValueFairValueMeasurementsUsingSignificantUnobservableInputsDetail" xlink:href="ango-20150831.xsd#FairValueFairValueMeasurementsUsingSignificantUnobservableInputsDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/FairValueFairValueOfAssetsAndLiabilitiesMeasuredOnRecurringBasisDetail" xlink:href="ango-20150831.xsd#FairValueFairValueOfAssetsAndLiabilitiesMeasuredOnRecurringBasisDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/FairValueSummaryShowingReconciliationOfContingentPaymentsDetail" xlink:href="ango-20150831.xsd#FairValueSummaryShowingReconciliationOfContingentPaymentsDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/FairValueSummaryShowingRecurringFairValueMeasurementsOfContingentConsiderationLiabilityDetail" xlink:href="ango-20150831.xsd#FairValueSummaryShowingRecurringFairValueMeasurementsOfContingentConsiderationLiabilityDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/FairValueTables" xlink:href="ango-20150831.xsd#FairValueTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssets" xlink:href="ango-20150831.xsd#GoodwillAndIntangibleAssets" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsAdditionalInformationDetail" xlink:href="ango-20150831.xsd#GoodwillAndIntangibleAssetsAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsGoodwillBySegmentDetail" xlink:href="ango-20150831.xsd#GoodwillAndIntangibleAssetsGoodwillBySegmentDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsIntangibleAssetsDetail" xlink:href="ango-20150831.xsd#GoodwillAndIntangibleAssetsIntangibleAssetsDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsTables" xlink:href="ango-20150831.xsd#GoodwillAndIntangibleAssetsTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ImmaterialCorrections" xlink:href="ango-20150831.xsd#ImmaterialCorrections" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ImmaterialCorrectionsDetails" xlink:href="ango-20150831.xsd#ImmaterialCorrectionsDetails" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ImmaterialCorrectionsTables" xlink:href="ango-20150831.xsd#ImmaterialCorrectionsTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/IncomeTaxes" xlink:href="ango-20150831.xsd#IncomeTaxes" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/IncomeTaxesAdditionalInformationDetail" xlink:href="ango-20150831.xsd#IncomeTaxesAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/IncomeTaxesComponentsOfIncomeTaxExpenseBenefitDetail" xlink:href="ango-20150831.xsd#IncomeTaxesComponentsOfIncomeTaxExpenseBenefitDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/IncomeTaxesNetOperatingLossCarryforwardsDetails" xlink:href="ango-20150831.xsd#IncomeTaxesNetOperatingLossCarryforwardsDetails" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/IncomeTaxesTables" xlink:href="ango-20150831.xsd#IncomeTaxesTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/Inventories" xlink:href="ango-20150831.xsd#Inventories" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/InventoriesScheduleOfInventoriesDetail" xlink:href="ango-20150831.xsd#InventoriesScheduleOfInventoriesDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/InventoriesTables" xlink:href="ango-20150831.xsd#InventoriesTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/LongTermDebt" xlink:href="ango-20150831.xsd#LongTermDebt" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/LongTermDebtAdditionalInformationDetail" xlink:href="ango-20150831.xsd#LongTermDebtAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/MarketableSecurities" xlink:href="ango-20150831.xsd#MarketableSecurities" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/MarketableSecuritiesAdditionalInformationDetail" xlink:href="ango-20150831.xsd#MarketableSecuritiesAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/MarketableSecuritiesMarketableSecuritiesDetail" xlink:href="ango-20150831.xsd#MarketableSecuritiesMarketableSecuritiesDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/MarketableSecuritiesTables" xlink:href="ango-20150831.xsd#MarketableSecuritiesTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/RecentlyIssuedAccountingPronouncements" xlink:href="ango-20150831.xsd#RecentlyIssuedAccountingPronouncements" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/Restructuring" xlink:href="ango-20150831.xsd#Restructuring" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/RestructuringAdditionalInformationDetail" xlink:href="ango-20150831.xsd#RestructuringAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/SegmentAndGeographicInformation" xlink:href="ango-20150831.xsd#SegmentAndGeographicInformation" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/SegmentAndGeographicInformationAdditionalInformationDetail" xlink:href="ango-20150831.xsd#SegmentAndGeographicInformationAdditionalInformationDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/SegmentAndGeographicInformationSummaryOfNetSalesByGeographicAreaDetail" xlink:href="ango-20150831.xsd#SegmentAndGeographicInformationSummaryOfNetSalesByGeographicAreaDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/SegmentAndGeographicInformationSummaryOfNetSalesByProductCategoryDetail" xlink:href="ango-20150831.xsd#SegmentAndGeographicInformationSummaryOfNetSalesByProductCategoryDetail" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/SegmentAndGeographicInformationTables" xlink:href="ango-20150831.xsd#SegmentAndGeographicInformationTables" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ShareBasedCompensation" xlink:href="ango-20150831.xsd#ShareBasedCompensation" xlink:type="simple"/>
<roleRef roleURI="http://www.angiodynamics.com/role/ShareBasedCompensationDetails" xlink:href="ango-20150831.xsd#ShareBasedCompensationDetails" xlink:type="simple"/>
<arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" xlink:type="simple"/>
<arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" xlink:type="simple"/>
<arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" xlink:type="simple"/>
<arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" xlink:type="simple"/>
<arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" xlink:type="simple"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/AccruedLiabilities" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/AccruedLiabilitiesSummaryOfAccruedLiabilitiesDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/AccruedLiabilitiesTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/Acquisitions" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/AcquisitionsAdditionalInformationDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_95D449A9CCA438D864A11A5B74AEBFE6" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_26EFE1ED5E2150DDF05F1A5B74A75017" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_95D449A9CCA438D864A11A5B74AEBFE6" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_26EFE1ED5E2150DDF05F1A5B74A75017" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_BC70BB1D276650D3BD8A1A5B74A81595" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_26EFE1ED5E2150DDF05F1A5B74A75017" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_BC70BB1D276650D3BD8A1A5B74A81595" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B6A823364FCF771C8CF11A5B74A8794D_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_BC70BB1D276650D3BD8A1A5B74A81595" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B6A823364FCF771C8CF11A5B74A8794D_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B6A823364FCF771C8CF11A5B74A8794D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_BC70BB1D276650D3BD8A1A5B74A81595" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B6A823364FCF771C8CF11A5B74A8794D" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ResearchAndDevelopmentMember" xlink:label="loc_ango_ResearchAndDevelopmentMember_F718811B7A47881ED17C1A5B74A824AD" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B6A823364FCF771C8CF11A5B74A8794D" xlink:to="loc_ango_ResearchAndDevelopmentMember_F718811B7A47881ED17C1A5B74A824AD" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CustomerRelationshipsMember" xlink:label="loc_us-gaap_CustomerRelationshipsMember_20EC00F40DB667D7D2361A5B74A82D21" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B6A823364FCF771C8CF11A5B74A8794D" xlink:to="loc_us-gaap_CustomerRelationshipsMember_20EC00F40DB667D7D2361A5B74A82D21" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TrademarksMember" xlink:label="loc_us-gaap_TrademarksMember_62AE0AF0ECFA8ABA16CE1A5B74A8E1DB" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B6A823364FCF771C8CF11A5B74A8794D" xlink:to="loc_us-gaap_TrademarksMember_62AE0AF0ECFA8ABA16CE1A5B74A8E1DB" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_F128FE8D2240D090B8111A5B74AD9A71" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_26EFE1ED5E2150DDF05F1A5B74A75017" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_F128FE8D2240D090B8111A5B74AD9A71" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FC0146556894921D4F941A5B74ADB212_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_F128FE8D2240D090B8111A5B74AD9A71" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FC0146556894921D4F941A5B74ADB212_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FC0146556894921D4F941A5B74ADB212" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_F128FE8D2240D090B8111A5B74AD9A71" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FC0146556894921D4F941A5B74ADB212" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ClinicalDevicesBvMember" xlink:label="loc_ango_ClinicalDevicesBvMember_0CA9AF951E18C672895D1A5B74ADF794" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FC0146556894921D4F941A5B74ADB212" xlink:to="loc_ango_ClinicalDevicesBvMember_0CA9AF951E18C672895D1A5B74ADF794" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_A7EFE67F86213D2C28B01A5B74AE8853" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_26EFE1ED5E2150DDF05F1A5B74A75017" xlink:to="loc_us-gaap_RangeAxis_A7EFE67F86213D2C28B01A5B74AE8853" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_4BD4D66684598F2FB55F1A5B74AEAD2E_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_A7EFE67F86213D2C28B01A5B74AE8853" xlink:to="loc_us-gaap_RangeMember_4BD4D66684598F2FB55F1A5B74AEAD2E_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_4BD4D66684598F2FB55F1A5B74AEAD2E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_A7EFE67F86213D2C28B01A5B74AE8853" xlink:to="loc_us-gaap_RangeMember_4BD4D66684598F2FB55F1A5B74AEAD2E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_F636847EA20E1AC1EA591A5B74AED008" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_4BD4D66684598F2FB55F1A5B74AEAD2E" xlink:to="loc_us-gaap_MinimumMember_F636847EA20E1AC1EA591A5B74AED008" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_08D20C417E84E2B93FC91A5B74AE1D88" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_4BD4D66684598F2FB55F1A5B74AEAD2E" xlink:to="loc_us-gaap_MaximumMember_08D20C417E84E2B93FC91A5B74AE1D88" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_C3572687485B009F31841A5B74AE33A0" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_95D449A9CCA438D864A11A5B74AEBFE6" xlink:to="loc_us-gaap_Goodwill_C3572687485B009F31841A5B74AE33A0" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_D804865ED9AFC1198A821A5B74AEA813" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_95D449A9CCA438D864A11A5B74AEBFE6" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_D804865ED9AFC1198A821A5B74AEA813" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_A97BEFC9AA002F3CFF5E1A5B74AE141E" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_95D449A9CCA438D864A11A5B74AEBFE6" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_A97BEFC9AA002F3CFF5E1A5B74AE141E" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/CommitmentsAndContinfenciesAdditionalInformationDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaap_LossContingenciesTable_09BD107737E75956B3B88A69B5337EBB" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:to="loc_us-gaap_LossContingenciesTable_09BD107737E75956B3B88A69B5337EBB" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LitigationCaseAxis" xlink:label="loc_us-gaap_LitigationCaseAxis_D070C60F8CCF5261B2005FF1315F211B" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LossContingenciesTable_09BD107737E75956B3B88A69B5337EBB" xlink:to="loc_us-gaap_LitigationCaseAxis_D070C60F8CCF5261B2005FF1315F211B" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_7D33D08405518265B9C6E904DD3C17C5_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LitigationCaseAxis_D070C60F8CCF5261B2005FF1315F211B" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_7D33D08405518265B9C6E904DD3C17C5_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_6E4B43F47B495364864D8B60B43899F0" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LitigationCaseAxis_D070C60F8CCF5261B2005FF1315F211B" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_6E4B43F47B495364864D8B60B43899F0" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_BiolitecMember" xlink:label="loc_ango_BiolitecMember_F3AD2BC460C55382810F3151944F2C84" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_6E4B43F47B495364864D8B60B43899F0" xlink:to="loc_ango_BiolitecMember_F3AD2BC460C55382810F3151944F2C84" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_CrBardIncMember" xlink:label="loc_ango_CrBardIncMember_5C64DE6F15235BF0BA6DDA9E44CAEC51" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_6E4B43F47B495364864D8B60B43899F0" xlink:to="loc_ango_CrBardIncMember_5C64DE6F15235BF0BA6DDA9E44CAEC51" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_NumberOfLawsuits" xlink:label="loc_ango_NumberOfLawsuits_25A13CFF9B2E509FAEBF1B7A89E491F4" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:to="loc_ango_NumberOfLawsuits_25A13CFF9B2E509FAEBF1B7A89E491F4" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PartialJudgmentGranted" xlink:label="loc_ango_PartialJudgmentGranted_8AE7669E5C1F5889B0697408CC355016" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:to="loc_ango_PartialJudgmentGranted_8AE7669E5C1F5889B0697408CC355016" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LitigationSettlementAmount" xlink:label="loc_us-gaap_LitigationSettlementAmount_73A3150C954C5E9FB6A31608E9BB9E2C" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:to="loc_us-gaap_LitigationSettlementAmount_73A3150C954C5E9FB6A31608E9BB9E2C" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_NumberOfPatentsAssertedForReexamination" xlink:label="loc_ango_NumberOfPatentsAssertedForReexamination_02358310F5C352DDADE890EAECB4D01C" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:to="loc_ango_NumberOfPatentsAssertedForReexamination_02358310F5C352DDADE890EAECB4D01C" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_NumberOfPatentClaims" xlink:label="loc_ango_NumberOfPatentClaims_27F44FC89D3A599892F789CF0BA71560" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:to="loc_ango_NumberOfPatentClaims_27F44FC89D3A599892F789CF0BA71560" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PatentClaimRejections" xlink:label="loc_ango_PatentClaimRejections_5E1ACD2FD5CE54EEB9AA462649F4EE26" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_080B5B9D7E7B5B4A929BD81C61E71EC2" xlink:to="loc_ango_PatentClaimRejections_5E1ACD2FD5CE54EEB9AA462649F4EE26" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/CommitmentsAndContingencies" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedBalanceSheets" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedFinancialStatements" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedFinancialStatementsAdditionalInformationDetail" xlink:type="extended">
<loc xlink:href="ango-20150831.xsd#ango_RecentDevelopmentsLineItems" xlink:label="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:type="locator"/>
<loc xlink:href="ango-20150831.xsd#ango_RecentDevelopmentsTable" xlink:label="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_40428FA7157701514C81442F8A78A79E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_40428FA7157701514C81442F8A78A79E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_us-gaap_EquityMethodInvesteeNameDomain_F5587BE5F32602C02EC7442F8A78D9C5_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_40428FA7157701514C81442F8A78A79E" xlink:to="loc_us-gaap_EquityMethodInvesteeNameDomain_F5587BE5F32602C02EC7442F8A78D9C5_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_us-gaap_EquityMethodInvesteeNameDomain_F5587BE5F32602C02EC7442F8A78D9C5" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_40428FA7157701514C81442F8A78A79E" xlink:to="loc_us-gaap_EquityMethodInvesteeNameDomain_F5587BE5F32602C02EC7442F8A78D9C5" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_2009DE17BB6994DF1AA6442F8A780C45" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_2009DE17BB6994DF1AA6442F8A780C45" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_7730D7EE72B14735339A442F8A789372_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_2009DE17BB6994DF1AA6442F8A780C45" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_7730D7EE72B14735339A442F8A789372_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_7730D7EE72B14735339A442F8A789372" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_2009DE17BB6994DF1AA6442F8A780C45" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_7730D7EE72B14735339A442F8A789372" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_2345207B5F03C1FBE582442F8A781E36" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_2345207B5F03C1FBE582442F8A781E36" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_AE6487CC904212FFE109442F8A782A97_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_2345207B5F03C1FBE582442F8A781E36" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_AE6487CC904212FFE109442F8A782A97_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_AE6487CC904212FFE109442F8A782A97" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_2345207B5F03C1FBE582442F8A781E36" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_AE6487CC904212FFE109442F8A782A97" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_944F557E453AFAC77A5C442F8A782D8A" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_944F557E453AFAC77A5C442F8A782D8A" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9B6201ADB6FE3F76EE67442F8A78FC56_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_944F557E453AFAC77A5C442F8A782D8A" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9B6201ADB6FE3F76EE67442F8A78FC56_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9B6201ADB6FE3F76EE67442F8A78FC56" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_944F557E453AFAC77A5C442F8A782D8A" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9B6201ADB6FE3F76EE67442F8A78FC56" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TrademarksMember" xlink:label="loc_us-gaap_TrademarksMember_AF6A3540CCFBA73B9A81442F8A7964A2" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9B6201ADB6FE3F76EE67442F8A78FC56" xlink:to="loc_us-gaap_TrademarksMember_AF6A3540CCFBA73B9A81442F8A7964A2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GuaranteeObligationsByNatureAxis" xlink:label="loc_us-gaap_GuaranteeObligationsByNatureAxis_A3271206CB8BD8748C69442F8A79DFDD" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_GuaranteeObligationsByNatureAxis_A3271206CB8BD8748C69442F8A79DFDD" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GuaranteeObligationsNatureDomain" xlink:label="loc_us-gaap_GuaranteeObligationsNatureDomain_943B2D9E43E7703287A2442F8A792FA4_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_GuaranteeObligationsByNatureAxis_A3271206CB8BD8748C69442F8A79DFDD" xlink:to="loc_us-gaap_GuaranteeObligationsNatureDomain_943B2D9E43E7703287A2442F8A792FA4_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GuaranteeObligationsNatureDomain" xlink:label="loc_us-gaap_GuaranteeObligationsNatureDomain_943B2D9E43E7703287A2442F8A792FA4" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_GuaranteeObligationsByNatureAxis_A3271206CB8BD8748C69442F8A79DFDD" xlink:to="loc_us-gaap_GuaranteeObligationsNatureDomain_943B2D9E43E7703287A2442F8A792FA4" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_NewAgreementMember" xlink:label="loc_ango_NewAgreementMember_8429F132E3A3FFDDA2E8442F8A79BE0F" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GuaranteeObligationsNatureDomain_943B2D9E43E7703287A2442F8A792FA4" xlink:to="loc_ango_NewAgreementMember_8429F132E3A3FFDDA2E8442F8A79BE0F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="loc_us-gaap_VariableRateAxis_6C31E823061EF8A1100E442F8A79C076" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_VariableRateAxis_6C31E823061EF8A1100E442F8A79C076" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_850DEA84FF409664F3D9442F8A791CD3_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_VariableRateAxis_6C31E823061EF8A1100E442F8A79C076" xlink:to="loc_us-gaap_VariableRateDomain_850DEA84FF409664F3D9442F8A791CD3_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_850DEA84FF409664F3D9442F8A791CD3" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_VariableRateAxis_6C31E823061EF8A1100E442F8A79C076" xlink:to="loc_us-gaap_VariableRateDomain_850DEA84FF409664F3D9442F8A791CD3" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BaseRateMember" xlink:label="loc_us-gaap_BaseRateMember_481C6E37E80EF13BF095442F8A795DB4" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_VariableRateDomain_850DEA84FF409664F3D9442F8A791CD3" xlink:to="loc_us-gaap_BaseRateMember_481C6E37E80EF13BF095442F8A795DB4" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EurodollarMember" xlink:label="loc_us-gaap_EurodollarMember_C015A12C42E107EE6356442F8A79DCBC" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_VariableRateDomain_850DEA84FF409664F3D9442F8A791CD3" xlink:to="loc_us-gaap_EurodollarMember_C015A12C42E107EE6356442F8A79DCBC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_11DC2055AC5541C6F9B5442F8A79CA11" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_CreditFacilityAxis_11DC2055AC5541C6F9B5442F8A79CA11" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CreditFacilityAxis_11DC2055AC5541C6F9B5442F8A79CA11" xlink:to="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CreditFacilityAxis_11DC2055AC5541C6F9B5442F8A79CA11" xlink:to="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TermLoanFacilityMember" xlink:label="loc_ango_TermLoanFacilityMember_E84D591D49625B206513442F8A792E65" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1" xlink:to="loc_ango_TermLoanFacilityMember_E84D591D49625B206513442F8A792E65" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SeniorSecuredRevolvingCreditFacilityMember" xlink:label="loc_ango_SeniorSecuredRevolvingCreditFacilityMember_67CFEE8B65155C92AC86442F8A792D53" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1" xlink:to="loc_ango_SeniorSecuredRevolvingCreditFacilityMember_67CFEE8B65155C92AC86442F8A792D53" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_LettersOfCreditMember" xlink:label="loc_ango_LettersOfCreditMember_C79B56EAC0D44C6FDF37442F8A798DC7" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1" xlink:to="loc_ango_LettersOfCreditMember_C79B56EAC0D44C6FDF37442F8A798DC7" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SwingLineLoansMember" xlink:label="loc_ango_SwingLineLoansMember_535018B3DADF27A1283C442F8A79C0B9" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1" xlink:to="loc_ango_SwingLineLoansMember_535018B3DADF27A1283C442F8A79C0B9" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_3D9D8F151BDA8DDCC09F442F8A7993C7" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_978EA3305544CFCDE5CF442F8A796FD1" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_3D9D8F151BDA8DDCC09F442F8A7993C7" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_DB170E42AC31E6D12457442F8A7A81C4" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_RangeAxis_DB170E42AC31E6D12457442F8A7A81C4" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_CCDCF410F7E8C357B8FA442F8A7A5D7D_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_DB170E42AC31E6D12457442F8A7A81C4" xlink:to="loc_us-gaap_RangeMember_CCDCF410F7E8C357B8FA442F8A7A5D7D_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_CCDCF410F7E8C357B8FA442F8A7A5D7D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_DB170E42AC31E6D12457442F8A7A81C4" xlink:to="loc_us-gaap_RangeMember_CCDCF410F7E8C357B8FA442F8A7A5D7D" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_C795E438FEB0A3601059442F8A7AB249" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_CCDCF410F7E8C357B8FA442F8A7A5D7D" xlink:to="loc_us-gaap_MinimumMember_C795E438FEB0A3601059442F8A7AB249" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_C3084905342C31EFA249442F8A7A2EC8" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_CCDCF410F7E8C357B8FA442F8A7A5D7D" xlink:to="loc_us-gaap_MaximumMember_C3084905342C31EFA249442F8A7A2EC8" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_25EC400FE07EFA713EDF442F8A7AECD1" xlink:type="locator"/>
<definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_25EC400FE07EFA713EDF442F8A7AECD1" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_4249EAEF7E5CEAF6EE25442F8A7AEA61_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_25EC400FE07EFA713EDF442F8A7AECD1" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_4249EAEF7E5CEAF6EE25442F8A7AEA61_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_4249EAEF7E5CEAF6EE25442F8A7AEA61" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_25EC400FE07EFA713EDF442F8A7AECD1" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_4249EAEF7E5CEAF6EE25442F8A7AEA61" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_JpMorganChaseMember" xlink:label="loc_ango_JpMorganChaseMember_DCB435C3DF9431E7173F442F8A7AA6DE" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_4249EAEF7E5CEAF6EE25442F8A7AEA61" xlink:to="loc_ango_JpMorganChaseMember_DCB435C3DF9431E7173F442F8A7AA6DE" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_47BFF40D0E07492BD2D0442F8A7A2ACC" xlink:type="locator"/>
<definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ango_RecentDevelopmentsTable_F20F0C8C60B20623CBE9442F8A772956" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_47BFF40D0E07492BD2D0442F8A7A2ACC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_49CA5CE1DF9A54344885442F8A7A0BC4_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_47BFF40D0E07492BD2D0442F8A7A2ACC" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_49CA5CE1DF9A54344885442F8A7A0BC4_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_49CA5CE1DF9A54344885442F8A7A0BC4" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_47BFF40D0E07492BD2D0442F8A7A2ACC" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_49CA5CE1DF9A54344885442F8A7A0BC4" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ClinicalDevicesBvMember" xlink:label="loc_ango_ClinicalDevicesBvMember_5FDB2944D5C3ABEF0E76442F8A7A74FE" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_49CA5CE1DF9A54344885442F8A7A0BC4" xlink:to="loc_ango_ClinicalDevicesBvMember_5FDB2944D5C3ABEF0E76442F8A7A74FE" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SecuredLongTermDebtInitialBorrowingCapacity" xlink:label="loc_ango_SecuredLongTermDebtInitialBorrowingCapacity_45C7AA6C7A1590CDAB21442F8A7A6D7D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_SecuredLongTermDebtInitialBorrowingCapacity_45C7AA6C7A1590CDAB21442F8A7A6D7D" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearOne" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearOne_2641875B9109BFB36986442F8A7A6C70" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearOne_2641875B9109BFB36986442F8A7A6C70" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearTwo" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearTwo_F1BB10BFBFEFF5EB90AE442F8A7A25E6" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearTwo_F1BB10BFBFEFF5EB90AE442F8A7A25E6" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearThree" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearThree_482A8424BEC71DFF7798442F8A7F7A35" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearThree_482A8424BEC71DFF7798442F8A7F7A35" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFour" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFour_A7F5333B1665D088D51D442F8A8078EA" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFour_A7F5333B1665D088D51D442F8A8078EA" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFive" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFive_34F893408B2381A4F579442F8A803880" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFive_34F893408B2381A4F579442F8A803880" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMinimum" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMinimum_0D3831ABAC8CE2E36930442F8A80D24A" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMinimum_0D3831ABAC8CE2E36930442F8A80D24A" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMaximum" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMaximum_A4072B0422A98CFCE8C9442F8A802A42" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMaximum_A4072B0422A98CFCE8C9442F8A802A42" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_DebtInstrumentIncreaseInInterestRateInCaseOfDefault" xlink:label="loc_ango_DebtInstrumentIncreaseInInterestRateInCaseOfDefault_A26F0D2AF2CD51F0C4B2442F8A8027E2" xlink:type="locator"/>
<definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_DebtInstrumentIncreaseInInterestRateInCaseOfDefault_A26F0D2AF2CD51F0C4B2442F8A8027E2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityCommitmentFeePercentage" xlink:label="loc_us-gaap_LineOfCreditFacilityCommitmentFeePercentage_D7A4A18A6AF899ADABA2442F8A8057AD" xlink:type="locator"/>
<definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_us-gaap_LineOfCreditFacilityCommitmentFeePercentage_D7A4A18A6AF899ADABA2442F8A8057AD" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_RevolvingFacilityDebt" xlink:label="loc_ango_RevolvingFacilityDebt_5E25FE610888A4E849E4442F8A80AD96" xlink:type="locator"/>
<definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_RevolvingFacilityDebt_5E25FE610888A4E849E4442F8A80AD96" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_DebtServiceCoverageRatio" xlink:label="loc_ango_DebtServiceCoverageRatio_181D0C4DFB7E790246D5442F8A809E0D" xlink:type="locator"/>
<definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_DebtServiceCoverageRatio_181D0C4DFB7E790246D5442F8A809E0D" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_RatioofIndebtednesstoConsolidatedEBITDA" xlink:label="loc_ango_RatioofIndebtednesstoConsolidatedEBITDA_F7770BA3514C952DE2F9442F8A80760C" xlink:type="locator"/>
<definitionArc order="13" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_ango_RatioofIndebtednesstoConsolidatedEBITDA_F7770BA3514C952DE2F9442F8A80760C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_73947852212497022C29442F8A813B39" xlink:type="locator"/>
<definitionArc order="14" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ango_RecentDevelopmentsLineItems_8B41C76CDE63B67AB279442F8A7A3ADC" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_73947852212497022C29442F8A813B39" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedStatementOfStockholdersEquity" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_F9CFC9C62D4057BCBD1A845BD3C21E36" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StatementTable_F9CFC9C62D4057BCBD1A845BD3C21E36" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_936A7B761B345DE99EAA7025B53436AA" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_F9CFC9C62D4057BCBD1A845BD3C21E36" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_936A7B761B345DE99EAA7025B53436AA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_95EA25051BD5050B25D5E904DD1E5169_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_936A7B761B345DE99EAA7025B53436AA" xlink:to="loc_us-gaap_EquityComponentDomain_95EA25051BD5050B25D5E904DD1E5169_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_F1BC7904D64A53F7B6E86285E4BA6763" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_936A7B761B345DE99EAA7025B53436AA" xlink:to="loc_us-gaap_EquityComponentDomain_F1BC7904D64A53F7B6E86285E4BA6763" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_A8E855C36000570782795B3C2AF502BB" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_F1BC7904D64A53F7B6E86285E4BA6763" xlink:to="loc_us-gaap_CommonStockMember_A8E855C36000570782795B3C2AF502BB" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_F24BC98919F35F4DA8B6382C8A72919C" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_F1BC7904D64A53F7B6E86285E4BA6763" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_F24BC98919F35F4DA8B6382C8A72919C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_C1D65534FA3A52239D52304653DBC311" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_F1BC7904D64A53F7B6E86285E4BA6763" xlink:to="loc_us-gaap_RetainedEarningsMember_C1D65534FA3A52239D52304653DBC311" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_1F22FCAA2C2855638C2073C94B0346BD" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_F1BC7904D64A53F7B6E86285E4BA6763" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_1F22FCAA2C2855638C2073C94B0346BD" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TreasuryStockMember" xlink:label="loc_us-gaap_TreasuryStockMember_AE485980C4EC5704935C9EA19355BD06" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_F1BC7904D64A53F7B6E86285E4BA6763" xlink:to="loc_us-gaap_TreasuryStockMember_AE485980C4EC5704935C9EA19355BD06" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_705AB27CF894596C9E3C736B399A0A93" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StockholdersEquity_705AB27CF894596C9E3C736B399A0A93" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaap_SharesIssued_8D8B1C8EC7F55813B8CAD9A2C5CB735C" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_SharesIssued_8D8B1C8EC7F55813B8CAD9A2C5CB735C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TreasuryStockShares" xlink:label="loc_us-gaap_TreasuryStockShares_A0574975AD265087B2CA79FE2D7F8FBF" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_TreasuryStockShares_A0574975AD265087B2CA79FE2D7F8FBF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_3FBF6DB4393D5127B8CAA79B81255267" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_NetIncomeLoss_3FBF6DB4393D5127B8CAA79B81255267" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_4852A2748CD758C7A306BC5DEC985E66" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_4852A2748CD758C7A306BC5DEC985E66" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_908AD11F263D517B8696B02AC3F0A654" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_908AD11F263D517B8696B02AC3F0A654" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_401B0B952BCF58A2BF93C4A1AFB35C50" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_401B0B952BCF58A2BF93C4A1AFB35C50" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_936AA951B0A9580D9F00B6279E997A0E" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_936AA951B0A9580D9F00B6279E997A0E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_0ABF7E462F955B9A9EBE0171D968C559" xlink:type="locator"/>
<definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_0ABF7E462F955B9A9EBE0171D968C559" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_9003BACF51715D869A7A32D4CAB0A574" xlink:type="locator"/>
<definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_9003BACF51715D869A7A32D4CAB0A574" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_7096C9CD08905D8B991523E7B8E32C3E" xlink:type="locator"/>
<definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_7096C9CD08905D8B991523E7B8E32C3E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_B8F5859E441A59A6BF4ECAFD20AE8236" xlink:type="locator"/>
<definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_77937E548F725C2BAF1DA3315354FF82" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_B8F5859E441A59A6BF4ECAFD20AE8236" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedStatementsOfCashFlows" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedStatementsOfComprehensiveIncome" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ConsolidatedStatementsOfIncome" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/DocumentAndEntityInformation" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/EarningsPerShare" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/EarningsPerShareAdditionalInformationDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/EarningsPerShareReconciliationOfBasicToDilutedWeightedAverageSharesOutstandingDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/EarningsPerShareTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/FairValue" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/FairValueAdditionalInformationDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/FairValueFairValueMeasurementsUsingSignificantUnobservableInputsDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_7F601CA75EB05B55BB98172D33A87969" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_7F601CA75EB05B55BB98172D33A87969" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_09ECE110840257FBB3B69470354BFA37" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_7F601CA75EB05B55BB98172D33A87969" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_09ECE110840257FBB3B69470354BFA37" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_22442548DBEEA0CACD819659350A3B2C_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_09ECE110840257FBB3B69470354BFA37" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_22442548DBEEA0CACD819659350A3B2C_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F3367BB6236E5A609655AC48BA8F50AF" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_09ECE110840257FBB3B69470354BFA37" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F3367BB6236E5A609655AC48BA8F50AF" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ClinicalDevicesBvMember" xlink:label="loc_ango_ClinicalDevicesBvMember_BB6B339790A854FAA2ED1944A48E65CF" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F3367BB6236E5A609655AC48BA8F50AF" xlink:to="loc_ango_ClinicalDevicesBvMember_BB6B339790A854FAA2ED1944A48E65CF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_F7CB50B385BB517DA18FE6E8D6456FD1" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_F7CB50B385BB517DA18FE6E8D6456FD1" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_3079CA47D8C453CABF37E0106F59E363" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_3079CA47D8C453CABF37E0106F59E363" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetCurrencyTranslationAdjustment" xlink:label="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetCurrencyTranslationAdjustment_7320CD4D879B5F88A2B1FAE2A493231E" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetCurrencyTranslationAdjustment_7320CD4D879B5F88A2B1FAE2A493231E" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCurrencyTranslationAdjustment" xlink:label="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCurrencyTranslationAdjustment_D0F0F2558709536A8DF8C87AB074ED55" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCurrencyTranslationAdjustment_D0F0F2558709536A8DF8C87AB074ED55" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInOtherComprehensiveIncomeLoss" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInOtherComprehensiveIncomeLoss_3A5280F4770657AE9F2B46386E53FC47" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInOtherComprehensiveIncomeLoss_3A5280F4770657AE9F2B46386E53FC47" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_369A1A2463DD5B1895075B636026ED8E" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_369A1A2463DD5B1895075B636026ED8E" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetContingentConsiderationEarnOutAsset" xlink:label="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetContingentConsiderationEarnOutAsset_2DFC9A36F90A5A7F95B1F68FCC446BFD" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetContingentConsiderationEarnOutAsset_2DFC9A36F90A5A7F95B1F68FCC446BFD" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityContingentConsiderationEarnOutLiability" xlink:label="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityContingentConsiderationEarnOutLiability_2CF1194FCEED5F40AF790E18D4E5E8D8" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_7C54B24EC09D5D90A95F78D14E5E2BB8" xlink:to="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityContingentConsiderationEarnOutLiability_2CF1194FCEED5F40AF790E18D4E5E8D8" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/FairValueFairValueOfAssetsAndLiabilitiesMeasuredOnRecurringBasisDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_9B7C7E50A1D453AEB67B89DFAA8C82E4" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_500BDEC9B5765BCC84FE2DE1D716677B" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_9B7C7E50A1D453AEB67B89DFAA8C82E4" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_500BDEC9B5765BCC84FE2DE1D716677B" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E013BDC0C99A52DABFAB4F9568019D4C" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_500BDEC9B5765BCC84FE2DE1D716677B" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E013BDC0C99A52DABFAB4F9568019D4C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_3E1A87843259FFAC6554E904DD3C0EB7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E013BDC0C99A52DABFAB4F9568019D4C" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_3E1A87843259FFAC6554E904DD3C0EB7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_03E52C27572A5FC18005486A876F56B8" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E013BDC0C99A52DABFAB4F9568019D4C" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_03E52C27572A5FC18005486A876F56B8" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_E07025D8FAD459D4B086C8DAC86157FA" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_03E52C27572A5FC18005486A876F56B8" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_E07025D8FAD459D4B086C8DAC86157FA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_1B736994D4465F8BA57530B5B5ED2483" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_03E52C27572A5FC18005486A876F56B8" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_1B736994D4465F8BA57530B5B5ED2483" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_535342C1BE4655098A116A2DCE1CD993" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_03E52C27572A5FC18005486A876F56B8" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_535342C1BE4655098A116A2DCE1CD993" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_F968C10468C8530AA0E5A30841D32D92" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_500BDEC9B5765BCC84FE2DE1D716677B" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_F968C10468C8530AA0E5A30841D32D92" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_97DC43EB614E948E991DE904DD3C680E_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_F968C10468C8530AA0E5A30841D32D92" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_97DC43EB614E948E991DE904DD3C680E_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_603AEB0F7E9F5E60859445077C00425F" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_F968C10468C8530AA0E5A30841D32D92" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_603AEB0F7E9F5E60859445077C00425F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_6150BB473D8B502A927B88EB243D6392" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_603AEB0F7E9F5E60859445077C00425F" xlink:to="loc_us-gaap_InterestRateSwapMember_6150BB473D8B502A927B88EB243D6392" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ContingentConsiderationEarnOutLiabilityMember" xlink:label="loc_ango_ContingentConsiderationEarnOutLiabilityMember_E8EC075E773A5E548929E94B6B4C4443" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_603AEB0F7E9F5E60859445077C00425F" xlink:to="loc_ango_ContingentConsiderationEarnOutLiabilityMember_E8EC075E773A5E548929E94B6B4C4443" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_8BE67DF124425EBF93A37DFF00EBE5C7" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_500BDEC9B5765BCC84FE2DE1D716677B" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_8BE67DF124425EBF93A37DFF00EBE5C7" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_607348D65A67FBD6D0E4E904DD3CFFC8_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_8BE67DF124425EBF93A37DFF00EBE5C7" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_607348D65A67FBD6D0E4E904DD3CFFC8_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_CF5732C564D058C0B4B554D1C41B1C55" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_8BE67DF124425EBF93A37DFF00EBE5C7" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_CF5732C564D058C0B4B554D1C41B1C55" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_F7F78066311D5033A3AEDC6458E34FAB" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_CF5732C564D058C0B4B554D1C41B1C55" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_F7F78066311D5033A3AEDC6458E34FAB" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_0BEA056EB09654D081742E1DC030CE67" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_500BDEC9B5765BCC84FE2DE1D716677B" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_0BEA056EB09654D081742E1DC030CE67" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_2A23C1F198E70D1B5877E904DD3CAC8D_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_0BEA056EB09654D081742E1DC030CE67" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_2A23C1F198E70D1B5877E904DD3CAC8D_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_71F9262EA92E516282A5F7E7814C5FF9" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_0BEA056EB09654D081742E1DC030CE67" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_71F9262EA92E516282A5F7E7814C5FF9" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_F8177E89BBD155C9A1D34518F6865D2D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_71F9262EA92E516282A5F7E7814C5FF9" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_F8177E89BBD155C9A1D34518F6865D2D" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByAssetClassAxis" xlink:label="loc_us-gaap_FairValueByAssetClassAxis_1B3B4FD00A5D5D679AF383A14C3A1C3C" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_500BDEC9B5765BCC84FE2DE1D716677B" xlink:to="loc_us-gaap_FairValueByAssetClassAxis_1B3B4FD00A5D5D679AF383A14C3A1C3C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_7A6FCD021ED91BF2DF98E904DD3C5048_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByAssetClassAxis_1B3B4FD00A5D5D679AF383A14C3A1C3C" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_7A6FCD021ED91BF2DF98E904DD3C5048_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_8201C4E7767151E68D5D0D6AF34C77FC" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByAssetClassAxis_1B3B4FD00A5D5D679AF383A14C3A1C3C" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_8201C4E7767151E68D5D0D6AF34C77FC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MoneyMarketFundsMember" xlink:label="loc_us-gaap_MoneyMarketFundsMember_8BED3788DA4F55D28299B2C5A68BE0BA" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_8201C4E7767151E68D5D0D6AF34C77FC" xlink:to="loc_us-gaap_MoneyMarketFundsMember_8BED3788DA4F55D28299B2C5A68BE0BA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_1D28C0B8565B5363BE5B38EE3E4D72E0" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_9B7C7E50A1D453AEB67B89DFAA8C82E4" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_1D28C0B8565B5363BE5B38EE3E4D72E0" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_9564F0F0002D578998A2BD7DD1E1E9C9" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_1D28C0B8565B5363BE5B38EE3E4D72E0" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_9564F0F0002D578998A2BD7DD1E1E9C9" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AvailableForSaleSecurities" xlink:label="loc_us-gaap_AvailableForSaleSecurities_A05706E5FFD95773A779C912F801F1E3" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_1D28C0B8565B5363BE5B38EE3E4D72E0" xlink:to="loc_us-gaap_AvailableForSaleSecurities_A05706E5FFD95773A779C912F801F1E3" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_4513C1D2CB5752EBBC53F0540AE49924" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_1D28C0B8565B5363BE5B38EE3E4D72E0" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_4513C1D2CB5752EBBC53F0540AE49924" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_5AFB9697D126598D9FFF788AFAE866DD" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_9B7C7E50A1D453AEB67B89DFAA8C82E4" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_5AFB9697D126598D9FFF788AFAE866DD" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_4D0E631779EE5485B07828C58103C4D2" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_5AFB9697D126598D9FFF788AFAE866DD" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_4D0E631779EE5485B07828C58103C4D2" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/FairValueSummaryShowingReconciliationOfContingentPaymentsDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_D1F5D281A77458038F7E11F8034D8F4E" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_658FEB5452305C45B7C3444289BB7DEB" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_D1F5D281A77458038F7E11F8034D8F4E" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_658FEB5452305C45B7C3444289BB7DEB" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_9F33D6DBFE3257859BF109E04259C708" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_658FEB5452305C45B7C3444289BB7DEB" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_9F33D6DBFE3257859BF109E04259C708" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_3E61B26ECEEEF544D01C965934FE81D2_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_9F33D6DBFE3257859BF109E04259C708" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_3E61B26ECEEEF544D01C965934FE81D2_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_D3C7350F22675F03A4A21FFD2217630E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_9F33D6DBFE3257859BF109E04259C708" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_D3C7350F22675F03A4A21FFD2217630E" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ContingentConsiderationEarnOutLiabilityMember" xlink:label="loc_ango_ContingentConsiderationEarnOutLiabilityMember_C509D83603FB5BF3903656C9D6A2B4B2" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_D3C7350F22675F03A4A21FFD2217630E" xlink:to="loc_ango_ContingentConsiderationEarnOutLiabilityMember_C509D83603FB5BF3903656C9D6A2B4B2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_52F7D940DF5356E3B7F976C9B83CFB8F" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_658FEB5452305C45B7C3444289BB7DEB" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_52F7D940DF5356E3B7F976C9B83CFB8F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_1D9E79506F21ACD16EE8965934FE6BA2_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_52F7D940DF5356E3B7F976C9B83CFB8F" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_1D9E79506F21ACD16EE8965934FE6BA2_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_965F96C9AB6957FC9C9D0968EA92E994" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_52F7D940DF5356E3B7F976C9B83CFB8F" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_965F96C9AB6957FC9C9D0968EA92E994" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCurrencyTranslationAdjustment" xlink:label="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCurrencyTranslationAdjustment_8752DC06B978595E8EB8083168DE35A5" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_D1F5D281A77458038F7E11F8034D8F4E" xlink:to="loc_ango_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCurrencyTranslationAdjustment_8752DC06B978595E8EB8083168DE35A5" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_AD00DA4A0E27507B8CA6687BD630A91A" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_D1F5D281A77458038F7E11F8034D8F4E" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_AD00DA4A0E27507B8CA6687BD630A91A" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/FairValueSummaryShowingRecurringFairValueMeasurementsOfContingentConsiderationLiabilityDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_F5181E4964CA5F449276D047F608F654" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_8BC35C33853D5444B2C6FDD577521D98" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_F5181E4964CA5F449276D047F608F654" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_8BC35C33853D5444B2C6FDD577521D98" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_8929AF5BF4BD5F8B99259A474773CDF1" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_8BC35C33853D5444B2C6FDD577521D98" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_8929AF5BF4BD5F8B99259A474773CDF1" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FB33088DC31767483CF3E904DCCE2FAD_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_8929AF5BF4BD5F8B99259A474773CDF1" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FB33088DC31767483CF3E904DCCE2FAD_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_66C0DADFB3615A2CB9873CF69C697760" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_8929AF5BF4BD5F8B99259A474773CDF1" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_66C0DADFB3615A2CB9873CF69C697760" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_E33C448ADE71524093BF64931000A1A5" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_66C0DADFB3615A2CB9873CF69C697760" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_E33C448ADE71524093BF64931000A1A5" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EligibleItemOrGroupForFairValueOptionAxis" xlink:label="loc_us-gaap_EligibleItemOrGroupForFairValueOptionAxis_F03B49878BFB52E2B86BDCCC760CBE18" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_8BC35C33853D5444B2C6FDD577521D98" xlink:to="loc_us-gaap_EligibleItemOrGroupForFairValueOptionAxis_F03B49878BFB52E2B86BDCCC760CBE18" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueOptionEligibleItemOrGroupDomain" xlink:label="loc_us-gaap_FairValueOptionEligibleItemOrGroupDomain_88892A79BCE8BF82DFC1E904DCCEB6FB_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_EligibleItemOrGroupForFairValueOptionAxis_F03B49878BFB52E2B86BDCCC760CBE18" xlink:to="loc_us-gaap_FairValueOptionEligibleItemOrGroupDomain_88892A79BCE8BF82DFC1E904DCCEB6FB_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueOptionEligibleItemOrGroupDomain" xlink:label="loc_us-gaap_FairValueOptionEligibleItemOrGroupDomain_6FFFCE05CC25563AA6420C3EBFB4683C" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_EligibleItemOrGroupForFairValueOptionAxis_F03B49878BFB52E2B86BDCCC760CBE18" xlink:to="loc_us-gaap_FairValueOptionEligibleItemOrGroupDomain_6FFFCE05CC25563AA6420C3EBFB4683C" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_RangeOneMember" xlink:label="loc_ango_RangeOneMember_B020B11284B45BD98A9632B107E10668" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueOptionEligibleItemOrGroupDomain_6FFFCE05CC25563AA6420C3EBFB4683C" xlink:to="loc_ango_RangeOneMember_B020B11284B45BD98A9632B107E10668" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_RangeTwoMember" xlink:label="loc_ango_RangeTwoMember_3594F961288F5A888AA49814B6B6F78B" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueOptionEligibleItemOrGroupDomain_6FFFCE05CC25563AA6420C3EBFB4683C" xlink:to="loc_ango_RangeTwoMember_3594F961288F5A888AA49814B6B6F78B" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_EF585538E3DE55AB95445D14DC9F24CE" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_8BC35C33853D5444B2C6FDD577521D98" xlink:to="loc_us-gaap_RangeAxis_EF585538E3DE55AB95445D14DC9F24CE" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_B7FEC9050BB16BF7A3E1E904DCCE5432_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_EF585538E3DE55AB95445D14DC9F24CE" xlink:to="loc_us-gaap_RangeMember_B7FEC9050BB16BF7A3E1E904DCCE5432_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_8097BBE38F5754D9B24151ABF8DDC07C" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_EF585538E3DE55AB95445D14DC9F24CE" xlink:to="loc_us-gaap_RangeMember_8097BBE38F5754D9B24151ABF8DDC07C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_F40358FCE3095A5E8879903D179F360C" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_8097BBE38F5754D9B24151ABF8DDC07C" xlink:to="loc_us-gaap_MinimumMember_F40358FCE3095A5E8879903D179F360C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_6FC2938F89B758AA887780C02A56E6B4" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_8097BBE38F5754D9B24151ABF8DDC07C" xlink:to="loc_us-gaap_MaximumMember_6FC2938F89B758AA887780C02A56E6B4" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_074D615EABEE539485B89D1E6498B102" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_8BC35C33853D5444B2C6FDD577521D98" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_074D615EABEE539485B89D1E6498B102" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_64F24766335E5444C164E904DCCE95EB_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_074D615EABEE539485B89D1E6498B102" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_64F24766335E5444C164E904DCCE95EB_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_C752D9C17C2550B8B15A7E366914D098" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_074D615EABEE539485B89D1E6498B102" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_C752D9C17C2550B8B15A7E366914D098" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_0F2AD27A499F57D5925206481FA8B2BF" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_C752D9C17C2550B8B15A7E366914D098" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_0F2AD27A499F57D5925206481FA8B2BF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_C6487AA5AFEC5B6892C0781453A478FB" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_8BC35C33853D5444B2C6FDD577521D98" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_C6487AA5AFEC5B6892C0781453A478FB" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_277342019140F19B87D0E904DCCE1E77_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_C6487AA5AFEC5B6892C0781453A478FB" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_277342019140F19B87D0E904DCCE1E77_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_A74D11023D9053E5920126D9DF2A8ABA" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_C6487AA5AFEC5B6892C0781453A478FB" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_A74D11023D9053E5920126D9DF2A8ABA" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ContingentConsiderationEarnOutLiabilityMember" xlink:label="loc_ango_ContingentConsiderationEarnOutLiabilityMember_BD92253680D15B1F8CFE2B35076F5850" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_A74D11023D9053E5920126D9DF2A8ABA" xlink:to="loc_ango_ContingentConsiderationEarnOutLiabilityMember_BD92253680D15B1F8CFE2B35076F5850" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_A4FA32FF70625C4CAEE7648AE4C85C27" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_F5181E4964CA5F449276D047F608F654" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_A4FA32FF70625C4CAEE7648AE4C85C27" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueUnobservableInputDiscountRate" xlink:label="loc_ango_FairValueUnobservableInputDiscountRate_F68F31AC4C965082A57D22EAABA92EAA" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_F5181E4964CA5F449276D047F608F654" xlink:to="loc_ango_FairValueUnobservableInputDiscountRate_F68F31AC4C965082A57D22EAABA92EAA" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueInputsProbabilityOfPayment" xlink:label="loc_ango_FairValueInputsProbabilityOfPayment_04FD0534F4B95191B26444430A416319" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_F5181E4964CA5F449276D047F608F654" xlink:to="loc_ango_FairValueInputsProbabilityOfPayment_04FD0534F4B95191B26444430A416319" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_FairValueInputsProjectedFiscalYearOfPayment" xlink:label="loc_ango_FairValueInputsProjectedFiscalYearOfPayment_5525F7F272115CE19D91F01DF823E47E" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_F5181E4964CA5F449276D047F608F654" xlink:to="loc_ango_FairValueInputsProjectedFiscalYearOfPayment_5525F7F272115CE19D91F01DF823E47E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_048FC879BD465014B115382B32DCF4C5" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_F5181E4964CA5F449276D047F608F654" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_048FC879BD465014B115382B32DCF4C5" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/FairValueTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssets" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsAdditionalInformationDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_6F612777310565BF2684442F8A2789D2" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_CE59C9D8C3D7B4C7446D442F8A277B87" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_6F612777310565BF2684442F8A2789D2" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_CE59C9D8C3D7B4C7446D442F8A277B87" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_C063D3EBD33D51669E88442F8A277D9D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_CE59C9D8C3D7B4C7446D442F8A277B87" xlink:to="loc_us-gaap_RangeAxis_C063D3EBD33D51669E88442F8A277D9D" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_CDA1DC2DDCAEEBC1D06A442F8A274AFC_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_C063D3EBD33D51669E88442F8A277D9D" xlink:to="loc_us-gaap_RangeMember_CDA1DC2DDCAEEBC1D06A442F8A274AFC_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_CDA1DC2DDCAEEBC1D06A442F8A274AFC" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_C063D3EBD33D51669E88442F8A277D9D" xlink:to="loc_us-gaap_RangeMember_CDA1DC2DDCAEEBC1D06A442F8A274AFC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_78373A15EC12388460E9442F8A271478" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_CDA1DC2DDCAEEBC1D06A442F8A274AFC" xlink:to="loc_us-gaap_MaximumMember_78373A15EC12388460E9442F8A271478" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_88883F1062EE56698021442F8A2735FA" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_CDA1DC2DDCAEEBC1D06A442F8A274AFC" xlink:to="loc_us-gaap_MinimumMember_88883F1062EE56698021442F8A2735FA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ValuationTechniqueAxis" xlink:label="loc_us-gaap_ValuationTechniqueAxis_31085916D7136316823C442F8A27E1F8" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_CE59C9D8C3D7B4C7446D442F8A277B87" xlink:to="loc_us-gaap_ValuationTechniqueAxis_31085916D7136316823C442F8A27E1F8" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ValuationTechniqueDomain" xlink:label="loc_us-gaap_ValuationTechniqueDomain_95FCD74564C07DBFD5DC442F8A2774B0_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ValuationTechniqueAxis_31085916D7136316823C442F8A27E1F8" xlink:to="loc_us-gaap_ValuationTechniqueDomain_95FCD74564C07DBFD5DC442F8A2774B0_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ValuationTechniqueDomain" xlink:label="loc_us-gaap_ValuationTechniqueDomain_95FCD74564C07DBFD5DC442F8A2774B0" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ValuationTechniqueAxis_31085916D7136316823C442F8A27E1F8" xlink:to="loc_us-gaap_ValuationTechniqueDomain_95FCD74564C07DBFD5DC442F8A2774B0" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_4C22FD68E3DE75A0FC72442F8A2850AF" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_6F612777310565BF2684442F8A2789D2" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_4C22FD68E3DE75A0FC72442F8A2850AF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_D81D86CEC0918FCCE9EC442F8A28D5F7" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_6F612777310565BF2684442F8A2789D2" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_D81D86CEC0918FCCE9EC442F8A28D5F7" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsGoodwillBySegmentDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GoodwillLineItems" xlink:label="loc_us-gaap_GoodwillLineItems_0D47A92958585437B03B5859518BF68A" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfGoodwillTable" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_4F0EF58BCE2559F1BC3DF9321FDC4046" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_GoodwillLineItems_0D47A92958585437B03B5859518BF68A" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_4F0EF58BCE2559F1BC3DF9321FDC4046" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_15B74D00850A5782BE3D894391BB972B" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_4F0EF58BCE2559F1BC3DF9321FDC4046" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_15B74D00850A5782BE3D894391BB972B" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_30E8DAC17249A6A98791965935587726_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_15B74D00850A5782BE3D894391BB972B" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_30E8DAC17249A6A98791965935587726_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_B6AF9148EEB25BDF88C99292FED7B778" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_15B74D00850A5782BE3D894391BB972B" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_B6AF9148EEB25BDF88C99292FED7B778" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ClinicalDevicesBvMember" xlink:label="loc_ango_ClinicalDevicesBvMember_49E3693F8B0D5B5EB3CD13A153A32178" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_B6AF9148EEB25BDF88C99292FED7B778" xlink:to="loc_ango_ClinicalDevicesBvMember_49E3693F8B0D5B5EB3CD13A153A32178" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_BFE93C610D3C59A3BBDBCCBBCF4EFC8B" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_0D47A92958585437B03B5859518BF68A" xlink:to="loc_us-gaap_Goodwill_BFE93C610D3C59A3BBDBCCBBCF4EFC8B" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsIntangibleAssetsDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_3FD49673A27AFC52F23C442F8A0B1FDB" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_3FD49673A27AFC52F23C442F8A0B1FDB" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_4F809C26FB1FDDDF0B28442F8A0B27D2" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_3FD49673A27AFC52F23C442F8A0B1FDB" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_4F809C26FB1FDDDF0B28442F8A0B27D2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0E74C946F3F5F611581C442F8A0B0BF1_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_4F809C26FB1FDDDF0B28442F8A0B27D2" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0E74C946F3F5F611581C442F8A0B0BF1_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0E74C946F3F5F611581C442F8A0B0BF1" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_4F809C26FB1FDDDF0B28442F8A0B27D2" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0E74C946F3F5F611581C442F8A0B0BF1" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ResearchAndDevelopmentMember" xlink:label="loc_ango_ResearchAndDevelopmentMember_A34839C5FA1A484C0EFE442F8A0B766C" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0E74C946F3F5F611581C442F8A0B0BF1" xlink:to="loc_ango_ResearchAndDevelopmentMember_A34839C5FA1A484C0EFE442F8A0B766C" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TrademarkNamicMember" xlink:label="loc_ango_TrademarkNamicMember_059578AB9E9C30D19D90442F8A0C08C2" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0E74C946F3F5F611581C442F8A0B0BF1" xlink:to="loc_ango_TrademarkNamicMember_059578AB9E9C30D19D90442F8A0C08C2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_878483DA023E87262F7E442F8A0CC8D6" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_3FD49673A27AFC52F23C442F8A0B1FDB" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_878483DA023E87262F7E442F8A0CC8D6" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_878483DA023E87262F7E442F8A0CC8D6" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_878483DA023E87262F7E442F8A0CC8D6" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_ProductTechnologiesMember" xlink:label="loc_ango_ProductTechnologiesMember_FB536299917537EC6482442F8A0CD100" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F" xlink:to="loc_ango_ProductTechnologiesMember_FB536299917537EC6482442F8A0CD100" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CustomerRelationshipsMember" xlink:label="loc_us-gaap_CustomerRelationshipsMember_7A908E3A13AFAF823D75442F8A0CD624" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F" xlink:to="loc_us-gaap_CustomerRelationshipsMember_7A908E3A13AFAF823D75442F8A0CD624" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TrademarkNamicMember" xlink:label="loc_ango_TrademarkNamicMember_6CA212FBEAB7DE285397442F8A0C605A" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F" xlink:to="loc_ango_TrademarkNamicMember_6CA212FBEAB7DE285397442F8A0C605A" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LicenseAgreementTermsMember" xlink:label="loc_us-gaap_LicenseAgreementTermsMember_766C1812C70964B8C9AD442F8A0CB3AC" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F" xlink:to="loc_us-gaap_LicenseAgreementTermsMember_766C1812C70964B8C9AD442F8A0CB3AC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TrademarksMember" xlink:label="loc_us-gaap_TrademarksMember_48AF265528180FFCFB7E442F8A0CA443" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_62ECACC004E1D774BB9A442F8A0C337F" xlink:to="loc_us-gaap_TrademarksMember_48AF265528180FFCFB7E442F8A0CA443" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_53943646B871251ECADD442F8A0D404A" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_53943646B871251ECADD442F8A0D404A" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_9C9D2979A055F18607FE442F8A0D4A97" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_9C9D2979A055F18607FE442F8A0D4A97" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_7BA64113FC438D84C1DA442F8A0DE7B2" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_7BA64113FC438D84C1DA442F8A0DE7B2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_53A9AE6A919B7D7B5C3E442F8A0DEE75" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_53A9AE6A919B7D7B5C3E442F8A0DEE75" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_DCCD45D0D5057D216BA0442F8A0DF0AF" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_DCCD45D0D5057D216BA0442F8A0DF0AF" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_IndefiniteLivedIntangibleAssetsExcludingGoodwillNet" xlink:label="loc_ango_IndefiniteLivedIntangibleAssetsExcludingGoodwillNet_E58D21F1FF61CF4124CB442F8A0D65DB" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_ango_IndefiniteLivedIntangibleAssetsExcludingGoodwillNet_E58D21F1FF61CF4124CB442F8A0D65DB" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_2BE6D7ED1AE1E212CD90442F8A0DD36A" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_2BE6D7ED1AE1E212CD90442F8A0DD36A" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_37D96D3112C2C446CE29442F8A0D435F" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_13A0621D61E564E4B468442F8A0DCFBB" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_37D96D3112C2C446CE29442F8A0D435F" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/GoodwillAndIntangibleAssetsTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ImmaterialCorrections" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ImmaterialCorrectionsDetails" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems" xlink:label="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable" xlink:label="loc_us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable_9A8057F48D5C1DB82C061A5B724B2B3E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable_9A8057F48D5C1DB82C061A5B724B2B3E" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis" xlink:label="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis_60B3D35348E7949172731A5B724B1998" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable_9A8057F48D5C1DB82C061A5B724B2B3E" xlink:to="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis_60B3D35348E7949172731A5B724B1998" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AdjustmentsForErrorCorrectionDomain" xlink:label="loc_us-gaap_AdjustmentsForErrorCorrectionDomain_399590D32A2DFC0E25521A5B724BD024_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis_60B3D35348E7949172731A5B724B1998" xlink:to="loc_us-gaap_AdjustmentsForErrorCorrectionDomain_399590D32A2DFC0E25521A5B724BD024_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AdjustmentsForErrorCorrectionDomain" xlink:label="loc_us-gaap_AdjustmentsForErrorCorrectionDomain_399590D32A2DFC0E25521A5B724BD024" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis_60B3D35348E7949172731A5B724B1998" xlink:to="loc_us-gaap_AdjustmentsForErrorCorrectionDomain_399590D32A2DFC0E25521A5B724BD024" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_8F81588CAD200AFF8DBC1A5B724B23BB" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable_9A8057F48D5C1DB82C061A5B724B2B3E" xlink:to="loc_us-gaap_StatementScenarioAxis_8F81588CAD200AFF8DBC1A5B724B23BB" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_3B984F8F190B3E0FE1231A5B724B69C0_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementScenarioAxis_8F81588CAD200AFF8DBC1A5B724B23BB" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_3B984F8F190B3E0FE1231A5B724B69C0_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_3B984F8F190B3E0FE1231A5B724B69C0" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementScenarioAxis_8F81588CAD200AFF8DBC1A5B724B23BB" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_3B984F8F190B3E0FE1231A5B724B69C0" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SalesRevenueNet" xlink:label="loc_us-gaap_SalesRevenueNet_3104F553BF60357A1EB71A5B724C054D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_SalesRevenueNet_3104F553BF60357A1EB71A5B724C054D" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CostOfGoodsSold" xlink:label="loc_us-gaap_CostOfGoodsSold_A7493E2558AAE121219F1A5B724C34E4" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_CostOfGoodsSold_A7493E2558AAE121219F1A5B724C34E4" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GrossProfit" xlink:label="loc_us-gaap_GrossProfit_DC143BAAD056AAAE22741A5B724CCD0E" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_GrossProfit_DC143BAAD056AAAE22741A5B724CCD0E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OperatingExpenses" xlink:label="loc_us-gaap_OperatingExpenses_F5FDA1BE40F67A57A16B1A5B724DDB9F" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_OperatingExpenses_F5FDA1BE40F67A57A16B1A5B724DDB9F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_E431C38D88D8AF9603E51A5B724DC57E" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_OperatingIncomeLoss_E431C38D88D8AF9603E51A5B724DC57E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_502E97138FB862B868F41A5B724D8009" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_502E97138FB862B868F41A5B724D8009" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_7EB30FF56EB03ED5D6981A5B724D2237" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_7EB30FF56EB03ED5D6981A5B724D2237" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_C243E82B520357592B8D1A5B724D17D6" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_C243E82B520357592B8D1A5B724D17D6" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_BB8A21C7121850DC02061A5B724D30CA" xlink:type="locator"/>
<definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_NetIncomeLoss_BB8A21C7121850DC02061A5B724D30CA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_CB205540A276002E4D8F1A5B724D10C2" xlink:type="locator"/>
<definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_CB205540A276002E4D8F1A5B724D10C2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_5D50018FCB66E380E4771A5B724DEF2F" xlink:type="locator"/>
<definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_5D50018FCB66E380E4771A5B724DEF2F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_5957E67F318DE51888A11A5B724D7F58" xlink:type="locator"/>
<definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_InventoryNet_5957E67F318DE51888A11A5B724D7F58" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_7AC5103BB27B0A6C74611A5B724D1DFE" xlink:type="locator"/>
<definitionArc order="13" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_7AC5103BB27B0A6C74611A5B724D1DFE" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_54365AACF3D2C999A4F91A5B724E7F8B" xlink:type="locator"/>
<definitionArc order="14" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_AssetsCurrent_54365AACF3D2C999A4F91A5B724E7F8B" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_453BE231C31A2B8801B81A5B724EE29B" xlink:type="locator"/>
<definitionArc order="15" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_453BE231C31A2B8801B81A5B724EE29B" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_D4965EFE3B16B7545E3C1A5B724EE6E4" xlink:type="locator"/>
<definitionArc order="16" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_D4965EFE3B16B7545E3C1A5B724EE6E4" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_4C44AB22E4501F00F0701A5B72537166" xlink:type="locator"/>
<definitionArc order="17" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_Goodwill_4C44AB22E4501F00F0701A5B72537166" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DeferredTaxAssetsNetNoncurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsNetNoncurrent_0A8D9876B63EC773602D1A5B7253D3B3" xlink:type="locator"/>
<definitionArc order="18" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_DeferredTaxAssetsNetNoncurrent_0A8D9876B63EC773602D1A5B7253D3B3" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_4CF77633253EAF4EB8241A5B725391D9" xlink:type="locator"/>
<definitionArc order="19" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_Assets_4CF77633253EAF4EB8241A5B725391D9" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_31D98D6DE166DD615FAB1A5B7253333E" xlink:type="locator"/>
<definitionArc order="20" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_31D98D6DE166DD615FAB1A5B7253333E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_D3A6DA0DA3273F78C8891A5B72535C93" xlink:type="locator"/>
<definitionArc order="21" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_LiabilitiesCurrent_D3A6DA0DA3273F78C8891A5B72535C93" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_ED1061203F2CEA69C59C1A5B72535DC1" xlink:type="locator"/>
<definitionArc order="22" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_Liabilities_ED1061203F2CEA69C59C1A5B72535DC1" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_312B28F101A770FC62BD1A5B7253C28F" xlink:type="locator"/>
<definitionArc order="23" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_312B28F101A770FC62BD1A5B7253C28F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_7B58397056C00845CBEF1A5B72536523" xlink:type="locator"/>
<definitionArc order="24" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_7B58397056C00845CBEF1A5B72536523" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_900513C98E0B5D95BB4B1A5B725410D0" xlink:type="locator"/>
<definitionArc order="25" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_StockholdersEquity_900513C98E0B5D95BB4B1A5B725410D0" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_F04612B5FFB940AC641B1A5B7254473C" xlink:type="locator"/>
<definitionArc order="26" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_F04612B5FFB940AC641B1A5B7254473C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaap_AccountsPayableCurrent_7EDFD11060297BCAB1501A5B7254B8BC" xlink:type="locator"/>
<definitionArc order="27" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_AccountsPayableCurrent_7EDFD11060297BCAB1501A5B7254B8BC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_A339F6AB80190CAA50041A5B7254C95E" xlink:type="locator"/>
<definitionArc order="28" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_A339F6AB80190CAA50041A5B7254C95E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_A72A72A29F339F7B75C01A5B725434E3" xlink:type="locator"/>
<definitionArc order="29" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_4FD185661421682DD4861A5B724CBA38" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_A72A72A29F339F7B75C01A5B725434E3" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ImmaterialCorrectionsTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/IncomeTaxes" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/IncomeTaxesAdditionalInformationDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxExaminationLineItems" xlink:label="loc_us-gaap_IncomeTaxExaminationLineItems_A96CB8A46042CCC030671A5B73B82F9E" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxExaminationTable" xlink:label="loc_us-gaap_IncomeTaxExaminationTable_95A5757FFE70538C4E921A5B73B70BDE" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_A96CB8A46042CCC030671A5B73B82F9E" xlink:to="loc_us-gaap_IncomeTaxExaminationTable_95A5757FFE70538C4E921A5B73B70BDE" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_7503751D2E6EFAD2EBF01A5B73B81B4C" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeTaxExaminationTable_95A5757FFE70538C4E921A5B73B70BDE" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_7503751D2E6EFAD2EBF01A5B73B81B4C" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_E478B50D952D72F6052B1A5B73B88312_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_7503751D2E6EFAD2EBF01A5B73B81B4C" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_E478B50D952D72F6052B1A5B73B88312_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_E478B50D952D72F6052B1A5B73B88312" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_7503751D2E6EFAD2EBF01A5B73B81B4C" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_E478B50D952D72F6052B1A5B73B88312" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DomesticCountryMember" xlink:label="loc_us-gaap_DomesticCountryMember_E97949F841F1AE31E1301A5B73B8AA91" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_E478B50D952D72F6052B1A5B73B88312" xlink:to="loc_us-gaap_DomesticCountryMember_E97949F841F1AE31E1301A5B73B8AA91" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxAuthorityNameAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameAxis_31733BD80254197B3D1A1A5B73B8AF0F" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeTaxExaminationTable_95A5757FFE70538C4E921A5B73B70BDE" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameAxis_31733BD80254197B3D1A1A5B73B8AF0F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_230206C931A3ACAF7AF31A5B73B817F8_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_31733BD80254197B3D1A1A5B73B8AF0F" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_230206C931A3ACAF7AF31A5B73B817F8_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_230206C931A3ACAF7AF31A5B73B817F8" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_31733BD80254197B3D1A1A5B73B8AF0F" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_230206C931A3ACAF7AF31A5B73B817F8" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_3716CBEECCB28722257B1A5B73B807CD" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeTaxExaminationTable_95A5757FFE70538C4E921A5B73B70BDE" xlink:to="loc_us-gaap_RangeAxis_3716CBEECCB28722257B1A5B73B807CD" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_AC1E8EAE2F2B0189EEF91A5B73B896ED_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_3716CBEECCB28722257B1A5B73B807CD" xlink:to="loc_us-gaap_RangeMember_AC1E8EAE2F2B0189EEF91A5B73B896ED_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_AC1E8EAE2F2B0189EEF91A5B73B896ED" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_3716CBEECCB28722257B1A5B73B807CD" xlink:to="loc_us-gaap_RangeMember_AC1E8EAE2F2B0189EEF91A5B73B896ED" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_EffectiveIncomeTaxRateReconciliationBeforeDiscreetItemsPercent" xlink:label="loc_ango_EffectiveIncomeTaxRateReconciliationBeforeDiscreetItemsPercent_F16BE4290B9DA1920C681A5B73B824A3" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_A96CB8A46042CCC030671A5B73B82F9E" xlink:to="loc_ango_EffectiveIncomeTaxRateReconciliationBeforeDiscreetItemsPercent_F16BE4290B9DA1920C681A5B73B824A3" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_1ABECE4752F2F83D9D691A5B73BD226F" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_A96CB8A46042CCC030671A5B73B82F9E" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_1ABECE4752F2F83D9D691A5B73BD226F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_8AF342BD0975229C9E1E1A5B73BD098A" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_A96CB8A46042CCC030671A5B73B82F9E" xlink:to="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_8AF342BD0975229C9E1E1A5B73BD098A" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_OperatingLossCarryforwardsBusinessCombination" xlink:label="loc_ango_OperatingLossCarryforwardsBusinessCombination_90A51DA38E23655E5EBF1A5B73BD8DF3" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_A96CB8A46042CCC030671A5B73B82F9E" xlink:to="loc_ango_OperatingLossCarryforwardsBusinessCombination_90A51DA38E23655E5EBF1A5B73BD8DF3" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/IncomeTaxesComponentsOfIncomeTaxExpenseBenefitDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/IncomeTaxesNetOperatingLossCarryforwardsDetails" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OperatingLossCarryforwardsLineItems" xlink:label="loc_us-gaap_OperatingLossCarryforwardsLineItems_17A3CE605FFA5BFC845A84A2816BD76C" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_OperatingLossCarryforwardsTable" xlink:label="loc_us-gaap_OperatingLossCarryforwardsTable_C4D3489320735FB7BFD1F2BEFDDF082A" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_17A3CE605FFA5BFC845A84A2816BD76C" xlink:to="loc_us-gaap_OperatingLossCarryforwardsTable_C4D3489320735FB7BFD1F2BEFDDF082A" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TaxPeriodAxis" xlink:label="loc_us-gaap_TaxPeriodAxis_E468897CC608503D9F148588769FABE2" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_C4D3489320735FB7BFD1F2BEFDDF082A" xlink:to="loc_us-gaap_TaxPeriodAxis_E468897CC608503D9F148588769FABE2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TaxPeriodDomain" xlink:label="loc_us-gaap_TaxPeriodDomain_AA37FF1D320FE30C8FF89A1F1EB66A95_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_TaxPeriodAxis_E468897CC608503D9F148588769FABE2" xlink:to="loc_us-gaap_TaxPeriodDomain_AA37FF1D320FE30C8FF89A1F1EB66A95_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_TaxPeriodDomain" xlink:label="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_TaxPeriodAxis_E468897CC608503D9F148588769FABE2" xlink:to="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2017Member" xlink:label="loc_ango_TaxYear2017Member_C501AC084E7D5F20826493DB4E10C5D0" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2017Member_C501AC084E7D5F20826493DB4E10C5D0" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2019Member" xlink:label="loc_ango_TaxYear2019Member_547595AE943F5B43AD098F9B5A53E9B3" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2019Member_547595AE943F5B43AD098F9B5A53E9B3" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2020Member" xlink:label="loc_ango_TaxYear2020Member_1B08A258931E55E48FF0CC1D8D312076" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2020Member_1B08A258931E55E48FF0CC1D8D312076" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2022Member" xlink:label="loc_ango_TaxYear2022Member_2C483226F9755FDFA13CA3D6F6ED2CCB" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2022Member_2C483226F9755FDFA13CA3D6F6ED2CCB" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2023Member" xlink:label="loc_ango_TaxYear2023Member_EFA7BBE24D3859D3AC8E8E74EA68033A" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2023Member_EFA7BBE24D3859D3AC8E8E74EA68033A" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2027Member" xlink:label="loc_ango_TaxYear2027Member_CB8DAF41506A5303A586823AC99B2A77" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2027Member_CB8DAF41506A5303A586823AC99B2A77" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2028Member" xlink:label="loc_ango_TaxYear2028Member_C08895452F2A51C3823728E23E72CEA2" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2028Member_C08895452F2A51C3823728E23E72CEA2" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2029Member" xlink:label="loc_ango_TaxYear2029Member_5B217828184152B383CA54D01539C5F2" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2029Member_5B217828184152B383CA54D01539C5F2" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2030Member" xlink:label="loc_ango_TaxYear2030Member_ED5A870E0EF256298CFD96E0032F7C11" xlink:type="locator"/>
<definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2030Member_ED5A870E0EF256298CFD96E0032F7C11" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2031Member" xlink:label="loc_ango_TaxYear2031Member_4E0B2494678C557A908084E39812AA50" xlink:type="locator"/>
<definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2031Member_4E0B2494678C557A908084E39812AA50" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2032Member" xlink:label="loc_ango_TaxYear2032Member_904C05B0E53E50608E7C81171300868D" xlink:type="locator"/>
<definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2032Member_904C05B0E53E50608E7C81171300868D" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TaxYear2033Member" xlink:label="loc_ango_TaxYear2033Member_9819164102355D68BBA43ABBF809AFC9" xlink:type="locator"/>
<definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_BD763373B6905454B3592EBBAB0BA87C" xlink:to="loc_ango_TaxYear2033Member_9819164102355D68BBA43ABBF809AFC9" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_OperatingLossCarryforwardsBusinessCombination" xlink:label="loc_ango_OperatingLossCarryforwardsBusinessCombination_8E7E7EA2C1C451BB8112B21403AAE574" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_17A3CE605FFA5BFC845A84A2816BD76C" xlink:to="loc_ango_OperatingLossCarryforwardsBusinessCombination_8E7E7EA2C1C451BB8112B21403AAE574" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/IncomeTaxesTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/Inventories" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/InventoriesScheduleOfInventoriesDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/InventoriesTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/LongTermDebt" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/LongTermDebtAdditionalInformationDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_F50B79E3C51A514DAD4B249A7E494A52" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_F50B79E3C51A514DAD4B249A7E494A52" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_E4276E826BA3F25ED95476B281E1C464_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_F50B79E3C51A514DAD4B249A7E494A52" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_E4276E826BA3F25ED95476B281E1C464_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_D326E0F963FE5CF8BC4674D222C4C650" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_F50B79E3C51A514DAD4B249A7E494A52" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_D326E0F963FE5CF8BC4674D222C4C650" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TermLoanMember" xlink:label="loc_ango_TermLoanMember_8A993B9A05305E84A6B05852737891EA" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_D326E0F963FE5CF8BC4674D222C4C650" xlink:to="loc_ango_TermLoanMember_8A993B9A05305E84A6B05852737891EA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GuaranteeObligationsByNatureAxis" xlink:label="loc_us-gaap_GuaranteeObligationsByNatureAxis_E973E3CB345454B2A8F13DC2158FC9F2" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:to="loc_us-gaap_GuaranteeObligationsByNatureAxis_E973E3CB345454B2A8F13DC2158FC9F2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GuaranteeObligationsNatureDomain" xlink:label="loc_us-gaap_GuaranteeObligationsNatureDomain_B31A36564D36812FA93676B281E27CEF_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_GuaranteeObligationsByNatureAxis_E973E3CB345454B2A8F13DC2158FC9F2" xlink:to="loc_us-gaap_GuaranteeObligationsNatureDomain_B31A36564D36812FA93676B281E27CEF_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_GuaranteeObligationsNatureDomain" xlink:label="loc_us-gaap_GuaranteeObligationsNatureDomain_28F15837B61953328AEE45CCC75152A1" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_GuaranteeObligationsByNatureAxis_E973E3CB345454B2A8F13DC2158FC9F2" xlink:to="loc_us-gaap_GuaranteeObligationsNatureDomain_28F15837B61953328AEE45CCC75152A1" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_NewAgreementMember" xlink:label="loc_ango_NewAgreementMember_6E47D34762A85A4C8DE37A9A448E1892" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GuaranteeObligationsNatureDomain_28F15837B61953328AEE45CCC75152A1" xlink:to="loc_ango_NewAgreementMember_6E47D34762A85A4C8DE37A9A448E1892" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_F37475AC1AAC58F5BC8FE6B2D313A967" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:to="loc_us-gaap_CreditFacilityAxis_F37475AC1AAC58F5BC8FE6B2D313A967" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_BF41C24A29789BB8899B76B281E2D3E7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CreditFacilityAxis_F37475AC1AAC58F5BC8FE6B2D313A967" xlink:to="loc_us-gaap_CreditFacilityDomain_BF41C24A29789BB8899B76B281E2D3E7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_F3CC65FB19255FD99701A8A9CF8B63E5" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CreditFacilityAxis_F37475AC1AAC58F5BC8FE6B2D313A967" xlink:to="loc_us-gaap_CreditFacilityDomain_F3CC65FB19255FD99701A8A9CF8B63E5" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_TermLoanFacilityMember" xlink:label="loc_ango_TermLoanFacilityMember_C91212443EF15B279BD331FF3739B9FC" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_F3CC65FB19255FD99701A8A9CF8B63E5" xlink:to="loc_ango_TermLoanFacilityMember_C91212443EF15B279BD331FF3739B9FC" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SeniorSecuredRevolvingCreditFacilityMember" xlink:label="loc_ango_SeniorSecuredRevolvingCreditFacilityMember_C2316B3186115C458E34E8F83DEB8E17" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_F3CC65FB19255FD99701A8A9CF8B63E5" xlink:to="loc_ango_SeniorSecuredRevolvingCreditFacilityMember_C2316B3186115C458E34E8F83DEB8E17" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_LettersOfCreditMember" xlink:label="loc_ango_LettersOfCreditMember_3A54921A1EA15BAEAF9A46D71F0ADC63" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_F3CC65FB19255FD99701A8A9CF8B63E5" xlink:to="loc_ango_LettersOfCreditMember_3A54921A1EA15BAEAF9A46D71F0ADC63" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SwingLineLoansMember" xlink:label="loc_ango_SwingLineLoansMember_36B882508FBE5D10938EB4278A8586BC" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_F3CC65FB19255FD99701A8A9CF8B63E5" xlink:to="loc_ango_SwingLineLoansMember_36B882508FBE5D10938EB4278A8586BC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_A5451FBF7A565AC8A95FDC57A9D5C189" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_F3CC65FB19255FD99701A8A9CF8B63E5" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_A5451FBF7A565AC8A95FDC57A9D5C189" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="loc_us-gaap_VariableRateAxis_36F982B91CBE5BE6A66598081D0B6FE2" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:to="loc_us-gaap_VariableRateAxis_36F982B91CBE5BE6A66598081D0B6FE2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_2FCFFA083C0DC1075EB076B281E246E8_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_VariableRateAxis_36F982B91CBE5BE6A66598081D0B6FE2" xlink:to="loc_us-gaap_VariableRateDomain_2FCFFA083C0DC1075EB076B281E246E8_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_D4D997B4502E5E1DB59639CB028AA0C4" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_VariableRateAxis_36F982B91CBE5BE6A66598081D0B6FE2" xlink:to="loc_us-gaap_VariableRateDomain_D4D997B4502E5E1DB59639CB028AA0C4" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_BaseRateMember" xlink:label="loc_us-gaap_BaseRateMember_F574AC05E31E5F49BFBC3D70B34C79F9" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_VariableRateDomain_D4D997B4502E5E1DB59639CB028AA0C4" xlink:to="loc_us-gaap_BaseRateMember_F574AC05E31E5F49BFBC3D70B34C79F9" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_EurodollarMember" xlink:label="loc_us-gaap_EurodollarMember_13CD448CF03058D7AEA7711437DBDE06" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_VariableRateDomain_D4D997B4502E5E1DB59639CB028AA0C4" xlink:to="loc_us-gaap_EurodollarMember_13CD448CF03058D7AEA7711437DBDE06" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_19C74B94C65E59A48ED70C57A5539D25" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:to="loc_us-gaap_RangeAxis_19C74B94C65E59A48ED70C57A5539D25" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_0D4A3FE1A9AC3F2BFBA776B281E2E13D_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_19C74B94C65E59A48ED70C57A5539D25" xlink:to="loc_us-gaap_RangeMember_0D4A3FE1A9AC3F2BFBA776B281E2E13D_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_8A8C5E6E9DEF5DFE8F3982483C24BB81" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_19C74B94C65E59A48ED70C57A5539D25" xlink:to="loc_us-gaap_RangeMember_8A8C5E6E9DEF5DFE8F3982483C24BB81" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_2A888D24B4155194BE710A5673D9AC68" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_8A8C5E6E9DEF5DFE8F3982483C24BB81" xlink:to="loc_us-gaap_MinimumMember_2A888D24B4155194BE710A5673D9AC68" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_F8D97D99C4E35291B656398994144CCF" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_8A8C5E6E9DEF5DFE8F3982483C24BB81" xlink:to="loc_us-gaap_MaximumMember_F8D97D99C4E35291B656398994144CCF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_C0EF064DAFA0582E9E1C9314B71100FA" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_06A1C418658352539AAB646DC33356CC" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_C0EF064DAFA0582E9E1C9314B71100FA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_D84AF655B3C68D8C2ACC76B281E3AA6E_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_C0EF064DAFA0582E9E1C9314B71100FA" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_D84AF655B3C68D8C2ACC76B281E3AA6E_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_637585E4C4C45132AA69B1F227798AF2" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_C0EF064DAFA0582E9E1C9314B71100FA" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_637585E4C4C45132AA69B1F227798AF2" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_JpMorganChaseMember" xlink:label="loc_ango_JpMorganChaseMember_531824CB66D65D319C4D5C0EDF4F5437" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_637585E4C4C45132AA69B1F227798AF2" xlink:to="loc_ango_JpMorganChaseMember_531824CB66D65D319C4D5C0EDF4F5437" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SecuredLongTermDebtInitialBorrowingCapacity" xlink:label="loc_ango_SecuredLongTermDebtInitialBorrowingCapacity_14E90C7E7C3A5A7E860A2E5F4A150E84" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_SecuredLongTermDebtInitialBorrowingCapacity_14E90C7E7C3A5A7E860A2E5F4A150E84" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearOne" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearOne_41143D4222A95549BFF3608799517593" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearOne_41143D4222A95549BFF3608799517593" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearTwo" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearTwo_910C51A860D752A0A13D0F3247DB4D67" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearTwo_910C51A860D752A0A13D0F3247DB4D67" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearThree" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearThree_10FC9238172D5161A15A5A0DAFBFF04F" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearThree_10FC9238172D5161A15A5A0DAFBFF04F" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFour" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFour_275DA5DC4FF256BA99E1D5FD8C247E02" xlink:type="locator"/>
<definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFour_275DA5DC4FF256BA99E1D5FD8C247E02" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFive" xlink:label="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFive_4B1355474F735A42B022920D017B3F3D" xlink:type="locator"/>
<definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_PercentageOfQuarterlyRepaymentOfTermFacilityYearFive_4B1355474F735A42B022920D017B3F3D" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMinimum" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMinimum_AE805A8C1DC757FF8E110EAAA5D778B1" xlink:type="locator"/>
<definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMinimum_AE805A8C1DC757FF8E110EAAA5D778B1" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMaximum" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMaximum_AAC661F98EF95EF9AFB0371234ACB52E" xlink:type="locator"/>
<definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentageRateRangeMaximum_AAC661F98EF95EF9AFB0371234ACB52E" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_DebtInstrumentIncreaseInInterestRateInCaseOfDefault" xlink:label="loc_ango_DebtInstrumentIncreaseInInterestRateInCaseOfDefault_0FF57CC652DA540E9CC27C5D796E2CAC" xlink:type="locator"/>
<definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_DebtInstrumentIncreaseInInterestRateInCaseOfDefault_0FF57CC652DA540E9CC27C5D796E2CAC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LineOfCreditFacilityCommitmentFeePercentage" xlink:label="loc_us-gaap_LineOfCreditFacilityCommitmentFeePercentage_829791DE5259577B95A02A3B5E119ACF" xlink:type="locator"/>
<definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_us-gaap_LineOfCreditFacilityCommitmentFeePercentage_829791DE5259577B95A02A3B5E119ACF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_DerivativeNotionalAmount" xlink:label="loc_invest_DerivativeNotionalAmount_499D155AC00D509787BEC19B7C1F0457" xlink:type="locator"/>
<definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_invest_DerivativeNotionalAmount_499D155AC00D509787BEC19B7C1F0457" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_DerivativeFixedInterestRate" xlink:label="loc_us-gaap_DerivativeFixedInterestRate_1E933D870AD85737B62A03E7BE0C5AD2" xlink:type="locator"/>
<definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_us-gaap_DerivativeFixedInterestRate_1E933D870AD85737B62A03E7BE0C5AD2" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_RevolvingFacilityDebt" xlink:label="loc_ango_RevolvingFacilityDebt_6EC4E0A4D4C65FD6AF880422407C58E6" xlink:type="locator"/>
<definitionArc order="13" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_RevolvingFacilityDebt_6EC4E0A4D4C65FD6AF880422407C58E6" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_LongTermLoansPayable" xlink:label="loc_us-gaap_LongTermLoansPayable_D09419C5FE5D5236AE1999541FD59129" xlink:type="locator"/>
<definitionArc order="14" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_us-gaap_LongTermLoansPayable_D09419C5FE5D5236AE1999541FD59129" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_DebtServiceCoverageRatio" xlink:label="loc_ango_DebtServiceCoverageRatio_17EE6D63A4175DA2B924A6F3AEE1397B" xlink:type="locator"/>
<definitionArc order="15" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_DebtServiceCoverageRatio_17EE6D63A4175DA2B924A6F3AEE1397B" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_RatioofIndebtednesstoConsolidatedEBITDA" xlink:label="loc_ango_RatioofIndebtednesstoConsolidatedEBITDA_56FB5BDD8FB159BCAFC78A84F539E1C5" xlink:type="locator"/>
<definitionArc order="16" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8DBC211DFE9D5901BBF0ECA3399F83E8" xlink:to="loc_ango_RatioofIndebtednesstoConsolidatedEBITDA_56FB5BDD8FB159BCAFC78A84F539E1C5" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/MarketableSecurities" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/MarketableSecuritiesAdditionalInformationDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/MarketableSecuritiesMarketableSecuritiesDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_90EA79819D365D7A9884C60CA36F5C06" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_2752EA69151B5EDE8068EB8DB073E833" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_90EA79819D365D7A9884C60CA36F5C06" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_2752EA69151B5EDE8068EB8DB073E833" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_BD001980A17356E2B48F939E60B87B13" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable_2752EA69151B5EDE8068EB8DB073E833" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_BD001980A17356E2B48F939E60B87B13" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_FC739F9FFF5D1E057D55E904DCC4ABF8_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_BD001980A17356E2B48F939E60B87B13" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_FC739F9FFF5D1E057D55E904DCC4ABF8_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_D714FE7BA3125CE7BF946CF16F77F05B" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_BD001980A17356E2B48F939E60B87B13" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_D714FE7BA3125CE7BF946CF16F77F05B" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_5B3E417EA3DC537DAF603DCD4FBF6DDD" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_D714FE7BA3125CE7BF946CF16F77F05B" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_5B3E417EA3DC537DAF603DCD4FBF6DDD" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_B9F787A7102350DC81E91A4352D60B32" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_90EA79819D365D7A9884C60CA36F5C06" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_B9F787A7102350DC81E91A4352D60B32" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_121C82413082559390BB37AB3F3C27F2" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_90EA79819D365D7A9884C60CA36F5C06" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_121C82413082559390BB37AB3F3C27F2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_854262AA7EF45ECD9FD4156947B91AC7" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_90EA79819D365D7A9884C60CA36F5C06" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_854262AA7EF45ECD9FD4156947B91AC7" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_BCFFCCBC14BB52DDBCF763E4C580A7FD" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_90EA79819D365D7A9884C60CA36F5C06" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_BCFFCCBC14BB52DDBCF763E4C580A7FD" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/MarketableSecuritiesTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/RecentlyIssuedAccountingPronouncements" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/Restructuring" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/RestructuringAdditionalInformationDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_D6AB40CEDC4197F18450442F893D25C6" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_8E4AE12E1485F47A5346442F893C365D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_D6AB40CEDC4197F18450442F893D25C6" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_8E4AE12E1485F47A5346442F893C365D" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_4F64FFCA8409F8839E2F442F893C7D67" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_8E4AE12E1485F47A5346442F893C365D" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_4F64FFCA8409F8839E2F442F893C7D67" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_6AACDFC92A319AE7BFC5442F893C20B9_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_4F64FFCA8409F8839E2F442F893C7D67" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_6AACDFC92A319AE7BFC5442F893C20B9_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_6AACDFC92A319AE7BFC5442F893C20B9" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_4F64FFCA8409F8839E2F442F893C7D67" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_6AACDFC92A319AE7BFC5442F893C20B9" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SellingAndMarketingExpenseMember" xlink:label="loc_us-gaap_SellingAndMarketingExpenseMember_FDCB0CE1D1FE1A969E52442F893C3F76" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_6AACDFC92A319AE7BFC5442F893C20B9" xlink:to="loc_us-gaap_SellingAndMarketingExpenseMember_FDCB0CE1D1FE1A969E52442F893C3F76" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_2FFF599EDD282F5541AB442F893C4A4F" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_8E4AE12E1485F47A5346442F893C365D" xlink:to="loc_us-gaap_RangeAxis_2FFF599EDD282F5541AB442F893C4A4F" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_5BE5D878982913159BF3442F893C68DE_default" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_2FFF599EDD282F5541AB442F893C4A4F" xlink:to="loc_us-gaap_RangeMember_5BE5D878982913159BF3442F893C68DE_default" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_5BE5D878982913159BF3442F893C68DE" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_2FFF599EDD282F5541AB442F893C4A4F" xlink:to="loc_us-gaap_RangeMember_5BE5D878982913159BF3442F893C68DE" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_CE0EB5AC2CA7A62B9206442F893DCDFA" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_5BE5D878982913159BF3442F893C68DE" xlink:to="loc_us-gaap_MinimumMember_CE0EB5AC2CA7A62B9206442F893DCDFA" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_C044AD8F7E187F36B9C6442F893DABCC" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_5BE5D878982913159BF3442F893C68DE" xlink:to="loc_us-gaap_MaximumMember_C044AD8F7E187F36B9C6442F893DABCC" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SeveranceCosts1" xlink:label="loc_us-gaap_SeveranceCosts1_B6B2F8A96D634B226E6E442F893DF5E4" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_D6AB40CEDC4197F18450442F893D25C6" xlink:to="loc_us-gaap_SeveranceCosts1_B6B2F8A96D634B226E6E442F893DF5E4" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/SegmentAndGeographicInformation" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/SegmentAndGeographicInformationAdditionalInformationDetail" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/SegmentAndGeographicInformationSummaryOfNetSalesByGeographicAreaDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems" xlink:label="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_1B49FD8CFB235ABD8FE409C4FA47A0ED" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" xlink:label="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_211D83712BF552CF91EE12B6F18DEE8B" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_1B49FD8CFB235ABD8FE409C4FA47A0ED" xlink:to="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_211D83712BF552CF91EE12B6F18DEE8B" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ConsolidationItemsAxis" xlink:label="loc_us-gaap_ConsolidationItemsAxis_4989BC58134D5CDD935941D9C2909CCF" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_211D83712BF552CF91EE12B6F18DEE8B" xlink:to="loc_us-gaap_ConsolidationItemsAxis_4989BC58134D5CDD935941D9C2909CCF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_58A562C04711741AAEBBE904DCE259C7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ConsolidationItemsAxis_4989BC58134D5CDD935941D9C2909CCF" xlink:to="loc_us-gaap_ConsolidationItemsDomain_58A562C04711741AAEBBE904DCE259C7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_F410E466D3D65811BCAA05A068C8CDB4" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ConsolidationItemsAxis_4989BC58134D5CDD935941D9C2909CCF" xlink:to="loc_us-gaap_ConsolidationItemsDomain_F410E466D3D65811BCAA05A068C8CDB4" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ReportableGeographicalComponentsMember" xlink:label="loc_us-gaap_ReportableGeographicalComponentsMember_F3C2B7DCB54657D4879F460D0CD2467B" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConsolidationItemsDomain_F410E466D3D65811BCAA05A068C8CDB4" xlink:to="loc_us-gaap_ReportableGeographicalComponentsMember_F3C2B7DCB54657D4879F460D0CD2467B" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ProductOrServiceAxis" xlink:label="loc_us-gaap_ProductOrServiceAxis_C7D9BA40106C5EF2B04EFA0DD27746E7" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_211D83712BF552CF91EE12B6F18DEE8B" xlink:to="loc_us-gaap_ProductOrServiceAxis_C7D9BA40106C5EF2B04EFA0DD27746E7" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_C884C4B272D7E97B692CE904DCE21C4E_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ProductOrServiceAxis_C7D9BA40106C5EF2B04EFA0DD27746E7" xlink:to="loc_us-gaap_ProductsAndServicesDomain_C884C4B272D7E97B692CE904DCE21C4E_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_5598AD93CB6553A1856C65F7DF67571A" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ProductOrServiceAxis_C7D9BA40106C5EF2B04EFA0DD27746E7" xlink:to="loc_us-gaap_ProductsAndServicesDomain_5598AD93CB6553A1856C65F7DF67571A" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SupplyAgreementMember" xlink:label="loc_ango_SupplyAgreementMember_3F1E0716C939572CB72073CD587410C1" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductsAndServicesDomain_5598AD93CB6553A1856C65F7DF67571A" xlink:to="loc_ango_SupplyAgreementMember_3F1E0716C939572CB72073CD587410C1" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_StatementGeographicalAxis" xlink:label="loc_us-gaap_StatementGeographicalAxis_546577A842AC561FB81F2C7BA7226F95" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_211D83712BF552CF91EE12B6F18DEE8B" xlink:to="loc_us-gaap_StatementGeographicalAxis_546577A842AC561FB81F2C7BA7226F95" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SegmentGeographicalDomain" xlink:label="loc_us-gaap_SegmentGeographicalDomain_992A6AAB48A1046EFABDE904DCE2B5C7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementGeographicalAxis_546577A842AC561FB81F2C7BA7226F95" xlink:to="loc_us-gaap_SegmentGeographicalDomain_992A6AAB48A1046EFABDE904DCE2B5C7_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SegmentGeographicalDomain" xlink:label="loc_us-gaap_SegmentGeographicalDomain_2A70416D1FCD5EAF8D73AEC440EEC735" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementGeographicalAxis_546577A842AC561FB81F2C7BA7226F95" xlink:to="loc_us-gaap_SegmentGeographicalDomain_2A70416D1FCD5EAF8D73AEC440EEC735" xlink:type="arc"/>
<loc xlink:href="http://xbrl.sec.gov/country/2013/country-2013-01-31.xsd#country_US" xlink:label="loc_country_US_94FCA3BEDEFC5D518A540D508161ADC9" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentGeographicalDomain_2A70416D1FCD5EAF8D73AEC440EEC735" xlink:to="loc_country_US_94FCA3BEDEFC5D518A540D508161ADC9" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SegmentGeographicalGroupsOfCountriesGroupOtherMember" xlink:label="loc_ango_SegmentGeographicalGroupsOfCountriesGroupOtherMember_425900C7C8F45D9EB6B2E0B45B4D59BF" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentGeographicalDomain_2A70416D1FCD5EAF8D73AEC440EEC735" xlink:to="loc_ango_SegmentGeographicalGroupsOfCountriesGroupOtherMember_425900C7C8F45D9EB6B2E0B45B4D59BF" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SegmentsGeographicalAreasAbstract" xlink:label="loc_us-gaap_SegmentsGeographicalAreasAbstract_F6946E50C44B5FE2B20795292C2F41B2" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_1B49FD8CFB235ABD8FE409C4FA47A0ED" xlink:to="loc_us-gaap_SegmentsGeographicalAreasAbstract_F6946E50C44B5FE2B20795292C2F41B2" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SalesRevenueNet" xlink:label="loc_us-gaap_SalesRevenueNet_B94C38445045519383EAF3A641411FFB" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentsGeographicalAreasAbstract_F6946E50C44B5FE2B20795292C2F41B2" xlink:to="loc_us-gaap_SalesRevenueNet_B94C38445045519383EAF3A641411FFB" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/SegmentAndGeographicInformationSummaryOfNetSalesByProductCategoryDetail" xlink:type="extended">
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_05C58ED077B25D319EC521AA1DEBF6F8" xlink:type="locator"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_D51CA85667BA5A8ABC3159401EE532DF" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_05C58ED077B25D319EC521AA1DEBF6F8" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_D51CA85667BA5A8ABC3159401EE532DF" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ProductOrServiceAxis" xlink:label="loc_us-gaap_ProductOrServiceAxis_3D97F465BDCC53BF96ABBE4B0B2ED422" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_D51CA85667BA5A8ABC3159401EE532DF" xlink:to="loc_us-gaap_ProductOrServiceAxis_3D97F465BDCC53BF96ABBE4B0B2ED422" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_DECCB94256F6412D84D5E904DD649BBE_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ProductOrServiceAxis_3D97F465BDCC53BF96ABBE4B0B2ED422" xlink:to="loc_us-gaap_ProductsAndServicesDomain_DECCB94256F6412D84D5E904DD649BBE_3F4E3BF6BBE554ECB5A150841F99594E" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_29C84C0AEF485E8AA46DF2AA7E9983D0" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ProductOrServiceAxis_3D97F465BDCC53BF96ABBE4B0B2ED422" xlink:to="loc_us-gaap_ProductsAndServicesDomain_29C84C0AEF485E8AA46DF2AA7E9983D0" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_PeripheralVascularMember" xlink:label="loc_ango_PeripheralVascularMember_160FD69E4903575FA09B6271A5274F0D" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductsAndServicesDomain_29C84C0AEF485E8AA46DF2AA7E9983D0" xlink:to="loc_ango_PeripheralVascularMember_160FD69E4903575FA09B6271A5274F0D" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_VascularAccessMember" xlink:label="loc_ango_VascularAccessMember_D1E02FF21EFC5DB8B51722C483A17023" xlink:type="locator"/>
<definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductsAndServicesDomain_29C84C0AEF485E8AA46DF2AA7E9983D0" xlink:to="loc_ango_VascularAccessMember_D1E02FF21EFC5DB8B51722C483A17023" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_OncologySurgeryMember" xlink:label="loc_ango_OncologySurgeryMember_2629CF8E5F2C5D57BC69406A90673192" xlink:type="locator"/>
<definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductsAndServicesDomain_29C84C0AEF485E8AA46DF2AA7E9983D0" xlink:to="loc_ango_OncologySurgeryMember_2629CF8E5F2C5D57BC69406A90673192" xlink:type="arc"/>
<loc xlink:href="ango-20150831.xsd#ango_SupplyAgreementMember" xlink:label="loc_ango_SupplyAgreementMember_F6C4620BD9E751C2A58537A792D7C651" xlink:type="locator"/>
<definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductsAndServicesDomain_29C84C0AEF485E8AA46DF2AA7E9983D0" xlink:to="loc_ango_SupplyAgreementMember_F6C4620BD9E751C2A58537A792D7C651" xlink:type="arc"/>
<loc xlink:href="http://xbrl.fasb.org/us-gaap/2014/elts/us-gaap-2014-01-31.xsd#us-gaap_SalesRevenueNet" xlink:label="loc_us-gaap_SalesRevenueNet_A20B381221F9536E8EE4EC3544C2B44E" xlink:type="locator"/>
<definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_05C58ED077B25D319EC521AA1DEBF6F8" xlink:to="loc_us-gaap_SalesRevenueNet_A20B381221F9536E8EE4EC3544C2B44E" xlink:type="arc"/>
</definitionLink>
<definitionLink xlink:role="http://www.angiodynamics.com/role/SegmentAndGeographicInformationTables" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ShareBasedCompensation" xlink:type="extended"/>
<definitionLink xlink:role="http://www.angiodynamics.com/role/ShareBasedCompensationDetails" xlink:type="extended"/>
</linkbase>

↑Top
Filing Submission 0001275187-15-000022   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)
Copyright © 2024 Fran Finnegan & Company LLC – All Rights Reserved.
About — Privacy — Redactions — Help — Tue., Apr. 30, 9:00:25.1am ET