SEC Info℠  
    Home      Search      My Interests      Help      Sign In      Please Sign In

Dyadic International Inc – ‘10-K’ for 12/31/19 – ‘EX-101.PRE’

On:  Monday, 3/30/20, at 5:03pm ET   ·   For:  12/31/19   ·   Accession #:  1213809-20-18   ·   File #:  1-32513

Previous ‘10-K’:  ‘10-K’ on 3/27/19 for 12/31/18   ·   Next:  ‘10-K’ on 3/30/21 for 12/31/20   ·   Latest:  ‘10-K’ on 3/28/24 for 12/31/23   ·   1 Reference:  By:  Dyadic International Inc. – Latest ‘10-K’ on 3/28/24 for 12/31/23

Find Words in Filings emoji
 		  in    Show  and   ↓Hints

  As Of               Filer                 Filing    For·On·As Docs:Size

 3/30/20  Dyadic International Inc          10-K       12/31/19   61:7.5M

Annual Report   —   Form 10-K   —   Sect. 13 / 15(d) – SEA’34
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   1.04M 
 2: EX-4.2      Instrument Defining the Rights of Security Holders  HTML     33K 
 3: EX-10.11    Material Contract                                   HTML     16K 
 4: EX-31.1     Certification -- §302 - SOA'02                      HTML     28K 
 5: EX-31.2     Certification -- §302 - SOA'02                      HTML     27K 
 6: EX-32.1     Certification -- §906 - SOA'02                      HTML     21K 
 7: EX-32.2     Certification -- §906 - SOA'02                      HTML     21K 
41: R1          Document and Entity Information                     HTML     81K 
16: R2          Consolidated Balance Sheets                         HTML     94K 
30: R3          Consolidated Balance Sheets (Parenthetical)         HTML     41K 
54: R4          Consolidated Statements of Operations               HTML     58K 
43: R5          Consolidated Statements of Stockholders? Equity     HTML     53K 
17: R6          Consolidated Statements of Cash Flows               HTML     93K 
31: R7          Organization and Summary of Significant Accounting  HTML    129K 
                Policies                                                         
51: R8          Cash, Cash Equivalent, and Investments              HTML     95K 
46: R9          Research and Collaboration Agreements               HTML     40K 
26: R10         Income Taxes                                        HTML     80K 
22: R11         Commitments and Contingencies                       HTML     34K 
35: R12         Share-Based Compensation                            HTML     92K 
56: R13         Shareholders' Equity                                HTML     60K 
25: R14         Subsequent Events                                   HTML     27K 
21: R15         Organization and Summary of Significant Accounting  HTML    115K 
                Policies (Policies)                                              
34: R16         Organization and Summary of Significant Accounting  HTML     78K 
                Policies (Tables)                                                
55: R17         Cash, Cash Equivalent, and Investments (Tables)     HTML     93K 
28: R18         Income Taxes (Tables)                               HTML     80K 
20: R19         Commitments and Contingencies (Tables)              HTML     25K 
45: R20         Share-Based Compensation (Tables)                   HTML     86K 
52: R21         Shareholders' Equity (Tables)                       HTML     57K 
33: R22         Organization and Summary of Significant Accounting  HTML     70K 
                Policies - Textual (Details)                                     
15: R23         Organization and Summary of Significant Accounting  HTML     26K 
                Policies - Accounts Receivable (Details)                         
44: R24         Organization and Summary of Significant Accounting  HTML     32K 
                Policies - Prepaid Expenses and Other Current                    
                Assets (Details)                                                 
50: R25         Organization and Summary of Significant Accounting  HTML     29K 
                Policies - Accounts Payable (Details)                            
32: R26         Organization and Summary of Significant Accounting  HTML     29K 
                Policies - Accrued Expenses (Details)                            
14: R27         Organization and Summary of Significant Accounting  HTML     28K 
                Policies - Research and Development Costs                        
                (Details)                                                        
42: R28         Cash, Cash Equivalent, and Investments (Details)    HTML     58K 
53: R29         Research Collaboration and Sub-licensing            HTML     92K 
                Agreements (Details)                                             
58: R30         Income Taxes - Textual (Details)                    HTML     33K 
36: R31         Income Taxes - Components of Loss Before Income     HTML     26K 
                Taxes (Details)                                                  
18: R32         Income Taxes - (Benefit) Provision for Income Tax   HTML     29K 
                (Details)                                                        
23: R33         Income Taxes - Reconciliation Income Taxes          HTML     46K 
                (Details)                                                        
59: R34         Income Taxes - Deferred Income Tax Assets           HTML     38K 
                (Details)                                                        
37: R35         Commitments and Contingencies - Textual (Details)   HTML     44K 
19: R36         Commitments and Contingencies - Purchase            HTML     25K 
                Obligations (Details)                                            
24: R37         Share-Based Compensation - Textual (Details)        HTML     70K 
57: R38         Share-Based Compensation - Assumptions (Details)    HTML     41K 
38: R39         Share-Based Compensation - Stock Option Activity    HTML     66K 
                (Details)                                                        
47: R40         Share-Based Compensation - Stock Option Activity -  HTML     82K 
                Textual (Details)                                                
40: R41         Share-Based Compensation - Compensation Expense     HTML     27K 
                (Details)                                                        
13: R42         Shareholders' Equity - Textual (Details)            HTML     33K 
29: R43         Shareholders' Equity - Stock Repurchase (Details)   HTML     35K 
48: R44         Subsequent Events (Details)                         HTML     63K 
27: XML         IDEA XML File -- Filing Summary                      XML    102K 
39: XML         XBRL Instance -- dyai-20191231_htm                   XML   1.50M 
61: EXCEL       IDEA Workbook of Financial Reports                  XLSX     71K 
 9: EX-101.CAL  XBRL Calculations -- dyai-20191231_cal               XML    197K 
10: EX-101.DEF  XBRL Definitions -- dyai-20191231_def                XML    404K 
11: EX-101.LAB  XBRL Labels -- dyai-20191231_lab                     XML   1.30M 
12: EX-101.PRE  XBRL Presentations -- dyai-20191231_pre              XML    711K 
 8: EX-101.SCH  XBRL Schema -- dyai-20191231                         XSD    133K 
60: JSON        XBRL Instance as JSON Data -- MetaLinks              260±   396K 
49: ZIP         XBRL Zipped Folder -- 0001213809-20-000018-xbrl      Zip    342K

‘EX-101.PRE’   —   XBRL Presentations — dyai-20191231_pre

This Exhibit is an XBRL XML File.

                                                                                                                                                                                
<?xml version="1.0" encoding="windows-1252"?>
<!-- XBRL Document Created with Wdesk from Workiva -->
<!-- Copyright 2020 Workiva -->
<!-- r:62cd9607-c646-47d4-bb87-5f440e34d689,g:9aa84e3a-6ab2-4e1c-9b32-b3a92a5a8700 -->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
<link:roleRef roleURI="http://www.dyadic.com/role/DocumentandEntityInformation" xlink:type="simple" xlink:href="dyai-20191231.xsd#DocumentandEntityInformation"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/DocumentandEntityInformation" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_506058a9-02b5-4011-af46-f3b12c11997a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_DocumentType_506058a9-02b5-4011-af46-f3b12c11997a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentAnnualReport_071947b8-893d-4aff-97e8-97f7ec72d2c1" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentAnnualReport"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_DocumentAnnualReport_071947b8-893d-4aff-97e8-97f7ec72d2c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_19e440da-9374-4f1a-8987-fa6c20919953" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_DocumentPeriodEndDate_19e440da-9374-4f1a-8987-fa6c20919953" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_d348c8d9-9065-4836-b26f-da246053b356" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentTransitionReport"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_DocumentTransitionReport_d348c8d9-9065-4836-b26f-da246053b356" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_deedd446-0ff4-4678-96da-d95ef4e8cf34" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityFileNumber_deedd446-0ff4-4678-96da-d95ef4e8cf34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_86adb004-be3e-4a04-9158-33007e237aa1" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityRegistrantName_86adb004-be3e-4a04-9158-33007e237aa1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_b8399664-8b0e-408a-b399-7fbcccf8192a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityIncorporationStateCountryCode_b8399664-8b0e-408a-b399-7fbcccf8192a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_d1a14833-fcba-4639-bcd9-2cd238ca126a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityTaxIdentificationNumber_d1a14833-fcba-4639-bcd9-2cd238ca126a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_bd1fb595-adf0-4d0f-8a6a-c04077d35565" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityAddressAddressLine1_bd1fb595-adf0-4d0f-8a6a-c04077d35565" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_17a4e4ef-d410-427f-bb62-63d45f0f6e60" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine2"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityAddressAddressLine2_17a4e4ef-d410-427f-bb62-63d45f0f6e60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_b97ed37b-650c-484e-9efc-a7741bc29078" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown"/>
<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityAddressCityOrTown_b97ed37b-650c-484e-9efc-a7741bc29078" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_21783d19-8cd9-433e-b378-4716bfc773b0" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressStateOrProvince"/>
<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityAddressStateOrProvince_21783d19-8cd9-433e-b378-4716bfc773b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_7edaa6f6-6a07-43b2-8626-2724d13582fe" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode"/>
<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityAddressPostalZipCode_7edaa6f6-6a07-43b2-8626-2724d13582fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_c38c2133-07e1-4150-b00b-6cdde819bc72" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode"/>
<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_CityAreaCode_c38c2133-07e1-4150-b00b-6cdde819bc72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_253ed36c-4eb5-4084-8f41-02448ed4ea68" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber"/>
<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_LocalPhoneNumber_253ed36c-4eb5-4084-8f41-02448ed4ea68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_404adab0-76ad-417c-826a-0bd7cb471ce9" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_Security12bTitle"/>
<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_Security12bTitle_404adab0-76ad-417c-826a-0bd7cb471ce9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_14a79859-4a55-47cb-adb3-4e762d212349" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_TradingSymbol"/>
<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_TradingSymbol_14a79859-4a55-47cb-adb3-4e762d212349" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_b70eb3a6-224a-4589-9113-5033fa00bf47" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SecurityExchangeName"/>
<link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_SecurityExchangeName_b70eb3a6-224a-4589-9113-5033fa00bf47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityWellKnownSeasonedIssuer_68a0aed1-0036-488c-9e9b-345fc1941fe2" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityWellKnownSeasonedIssuer"/>
<link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityWellKnownSeasonedIssuer_68a0aed1-0036-488c-9e9b-345fc1941fe2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityVoluntaryFilers_6add666e-fc23-4b95-aca6-052cddbe9626" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityVoluntaryFilers"/>
<link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityVoluntaryFilers_6add666e-fc23-4b95-aca6-052cddbe9626" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_44ad9937-4801-45a2-ab4a-0136d722ede7" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCurrentReportingStatus"/>
<link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityCurrentReportingStatus_44ad9937-4801-45a2-ab4a-0136d722ede7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_0c4da2de-904b-4f8e-bbc8-9a3669319874" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityInteractiveDataCurrent"/>
<link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityInteractiveDataCurrent_0c4da2de-904b-4f8e-bbc8-9a3669319874" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_6b75fdbb-8dcf-4850-b9b1-f007ef2aef34" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFilerCategory"/>
<link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityFilerCategory_6b75fdbb-8dcf-4850-b9b1-f007ef2aef34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_76dc3b34-173a-4846-9392-65ada6b1ab11" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntitySmallBusiness"/>
<link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntitySmallBusiness_76dc3b34-173a-4846-9392-65ada6b1ab11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_b2210e68-e70a-41e3-b27c-550efcace26a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany"/>
<link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityEmergingGrowthCompany_b2210e68-e70a-41e3-b27c-550efcace26a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_fd0a5da7-68f8-464c-9472-73bcb9814a3e" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityShellCompany"/>
<link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityShellCompany_fd0a5da7-68f8-464c-9472-73bcb9814a3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityPublicFloat_f230f7e9-b05b-4a38-8e7c-29a1f789f1e8" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityPublicFloat"/>
<link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityPublicFloat_f230f7e9-b05b-4a38-8e7c-29a1f789f1e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_1d84be56-7d8a-4191-8f62-903826487e80" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCommonStockSharesOutstanding"/>
<link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_1d84be56-7d8a-4191-8f62-903826487e80" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_a0a002c6-ddd5-4dc9-a1a0-9faa83f9d882" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey"/>
<link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_EntityCentralIndexKey_a0a002c6-ddd5-4dc9-a1a0-9faa83f9d882" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_e8fc9335-3f6d-43d9-9a49-950450f76cd0" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CurrentFiscalYearEndDate"/>
<link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_CurrentFiscalYearEndDate_e8fc9335-3f6d-43d9-9a49-950450f76cd0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_33e80637-1313-45c8-93ae-0a310bc9ca39" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalYearFocus"/>
<link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_DocumentFiscalYearFocus_33e80637-1313-45c8-93ae-0a310bc9ca39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_1a976beb-7407-4db9-9d6c-1f9af37a6f1c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalPeriodFocus"/>
<link:presentationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_DocumentFiscalPeriodFocus_1a976beb-7407-4db9-9d6c-1f9af37a6f1c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_2237dd21-3e27-4ec6-b6cf-c92398694528" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag"/>
<link:presentationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_42d51d0d-d84e-4662-9011-a9024be089e8" xlink:to="loc_dei_AmendmentFlag_2237dd21-3e27-4ec6-b6cf-c92398694528" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="simple" xlink:href="dyai-20191231.xsd#CONSOLIDATEDBALANCESHEETS"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_094c608a-8be4-4347-a365-4232ce40002b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_e0141afc-66a9-46af-b291-22c7cec7739e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsAbstract"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_094c608a-8be4-4347-a365-4232ce40002b" xlink:to="loc_us-gaap_AssetsAbstract_e0141afc-66a9-46af-b291-22c7cec7739e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsCurrentAbstract"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_e0141afc-66a9-46af-b291-22c7cec7739e" xlink:to="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_105df0cb-7176-4678-b2bb-05ca199897a3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_105df0cb-7176-4678-b2bb-05ca199897a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesCurrent_48733724-cdd5-4b44-8116-6e07312c180d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_HeldToMaturitySecuritiesCurrent"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesCurrent_48733724-cdd5-4b44-8116-6e07312c180d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestReceivableCurrent_5ae6cd75-ccf6-4ef0-bdd9-d923b15cb98f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InterestReceivableCurrent"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_us-gaap_InterestReceivableCurrent_5ae6cd75-ccf6-4ef0-bdd9-d923b15cb98f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_441a4a9d-940a-4c5d-88dc-e19de19a3cc2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_441a4a9d-940a-4c5d-88dc-e19de19a3cc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxesReceivable_e9db5887-17ca-4bdf-b100-bd4e0ddc2754" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxesReceivable"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_us-gaap_IncomeTaxesReceivable_e9db5887-17ca-4bdf-b100-bd4e0ddc2754" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_PrepaidResearchandDevelopmentinProcessCurrent_01ce6a7d-3b54-424a-b051-eda6ee02c42f" xlink:href="dyai-20191231.xsd#dyai_PrepaidResearchandDevelopmentinProcessCurrent"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_dyai_PrepaidResearchandDevelopmentinProcessCurrent_01ce6a7d-3b54-424a-b051-eda6ee02c42f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_b457b616-1516-4ca9-a243-e8625fd5ff8a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_b457b616-1516-4ca9-a243-e8625fd5ff8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_61057551-99c9-402c-9c5d-64f6fffd2dad" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsCurrent"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_1f5c2585-c0c2-4964-a7a5-832e0b1edc66" xlink:to="loc_us-gaap_AssetsCurrent_61057551-99c9-402c-9c5d-64f6fffd2dad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsNoncurrentAbstract_e9a14946-8752-4b31-931c-8f4bf77853bb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsNoncurrentAbstract"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_e0141afc-66a9-46af-b291-22c7cec7739e" xlink:to="loc_us-gaap_AssetsNoncurrentAbstract_e9a14946-8752-4b31-931c-8f4bf77853bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesNoncurrent_82ffcf35-565f-4a22-9dd5-5d826cc57add" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_HeldToMaturitySecuritiesNoncurrent"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsNoncurrentAbstract_e9a14946-8752-4b31-931c-8f4bf77853bb" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesNoncurrent_82ffcf35-565f-4a22-9dd5-5d826cc57add" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxesReceivableNoncurrent_c830b7a1-60ca-431c-ab6e-98940c339319" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxesReceivableNoncurrent"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsNoncurrentAbstract_e9a14946-8752-4b31-931c-8f4bf77853bb" xlink:to="loc_us-gaap_IncomeTaxesReceivableNoncurrent_c830b7a1-60ca-431c-ab6e-98940c339319" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_4af9c136-51e9-4eaa-a7df-3850662e5e3e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsNoncurrentAbstract_e9a14946-8752-4b31-931c-8f4bf77853bb" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_4af9c136-51e9-4eaa-a7df-3850662e5e3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_de8e474a-f9f3-454c-aa21-90d2eddd49f4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Assets"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsNoncurrentAbstract_e9a14946-8752-4b31-931c-8f4bf77853bb" xlink:to="loc_us-gaap_Assets_de8e474a-f9f3-454c-aa21-90d2eddd49f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_7f275f5f-c3a7-4974-94fd-be98afb1b28a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_094c608a-8be4-4347-a365-4232ce40002b" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_7f275f5f-c3a7-4974-94fd-be98afb1b28a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_de726f45-ff5c-4779-b183-8f7e4de219d3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_7f275f5f-c3a7-4974-94fd-be98afb1b28a" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_de726f45-ff5c-4779-b183-8f7e4de219d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_93b05081-4774-431a-9043-649cc4110fc1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_de726f45-ff5c-4779-b183-8f7e4de219d3" xlink:to="loc_us-gaap_AccountsPayableCurrent_93b05081-4774-431a-9043-649cc4110fc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_c050ca05-41e5-44f7-86f9-767992ed2865" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_de726f45-ff5c-4779-b183-8f7e4de219d3" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_c050ca05-41e5-44f7-86f9-767992ed2865" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_7041b6ed-5ec6-4184-9a93-0061cb7d135f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_de726f45-ff5c-4779-b183-8f7e4de219d3" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_7041b6ed-5ec6-4184-9a93-0061cb7d135f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_d8c566d7-c81a-4275-9323-34fce989ad99" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_de726f45-ff5c-4779-b183-8f7e4de219d3" xlink:to="loc_us-gaap_LiabilitiesCurrent_d8c566d7-c81a-4275-9323-34fce989ad99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_83440e9b-83a7-4f30-8876-caede9f0cbdb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_7f275f5f-c3a7-4974-94fd-be98afb1b28a" xlink:to="loc_us-gaap_CommitmentsAndContingencies_83440e9b-83a7-4f30-8876-caede9f0cbdb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_7f275f5f-c3a7-4974-94fd-be98afb1b28a" xlink:to="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_a3a1e5c1-5f85-428b-aed8-4e32228abb14" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockValue"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:to="loc_us-gaap_PreferredStockValue_a3a1e5c1-5f85-428b-aed8-4e32228abb14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_1ba65474-4aea-4a6b-b828-4aedcf64c1dd" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockValue"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:to="loc_us-gaap_CommonStockValue_1ba65474-4aea-4a6b-b828-4aedcf64c1dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_84e08112-b0f4-4a36-8cd0-c359fd48c173" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdditionalPaidInCapital"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:to="loc_us-gaap_AdditionalPaidInCapital_84e08112-b0f4-4a36-8cd0-c359fd48c173" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValue_c260cb92-aec6-45e6-8d59-1eec30e4728b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockValue"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:to="loc_us-gaap_TreasuryStockValue_c260cb92-aec6-45e6-8d59-1eec30e4728b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_1a957ca7-5b05-4ffa-9bba-6bde2caf7de8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_1a957ca7-5b05-4ffa-9bba-6bde2caf7de8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_9ae3b4e7-ddcd-48d1-b187-1843ede945c6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_8237793d-cfcd-4168-8343-c14737a113cb" xlink:to="loc_us-gaap_StockholdersEquity_9ae3b4e7-ddcd-48d1-b187-1843ede945c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_20d4af66-274e-4659-99c2-6fb22c69cfa5" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_7f275f5f-c3a7-4974-94fd-be98afb1b28a" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_20d4af66-274e-4659-99c2-6fb22c69cfa5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CONSOLIDATEDBALANCESHEETSParenthetical" xlink:type="simple" xlink:href="dyai-20191231.xsd#CONSOLIDATEDBALANCESHEETSParenthetical"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CONSOLIDATEDBALANCESHEETSParenthetical" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_d3749163-fe29-4117-ae4a-2a7b3ff9c6d4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_d3749163-fe29-4117-ae4a-2a7b3ff9c6d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_2a284eda-b02b-4107-9304-5a4332bf88a6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesAuthorized"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_2a284eda-b02b-4107-9304-5a4332bf88a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesIssued_43e1ab9a-b0c5-4dce-880f-19ea01e89137" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesIssued"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_PreferredStockSharesIssued_43e1ab9a-b0c5-4dce-880f-19ea01e89137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_bb1f9573-8ca3-4b60-af3c-85f45c9993a2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesOutstanding"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_bb1f9573-8ca3-4b60-af3c-85f45c9993a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_07bbee65-3e70-4146-bf91-2a7c3ba0ea03" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_07bbee65-3e70-4146-bf91-2a7c3ba0ea03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_3028af29-4826-4219-a670-c89eb21ee654" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_3028af29-4826-4219-a670-c89eb21ee654" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_a4e684b6-6f24-4c9e-91e7-2c7026a4afa6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_CommonStockSharesIssued_a4e684b6-6f24-4c9e-91e7-2c7026a4afa6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_87db6e84-248b-4a9f-9f24-385e672938fa" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_87db6e84-248b-4a9f-9f24-385e672938fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonShares_9e109c54-f4ac-4c02-9c8f-a406e70c3d45" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockCommonShares"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_35ea10fd-0570-4ee8-ae31-2fdd7132db5e" xlink:to="loc_us-gaap_TreasuryStockCommonShares_9e109c54-f4ac-4c02-9c8f-a406e70c3d45" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="simple" xlink:href="dyai-20191231.xsd#CONSOLIDATEDSTATEMENTSOFOPERATIONS"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract_fddbda56-cfb5-4baf-b92b-2df8fc742d21" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenuesAbstract"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_RevenuesAbstract_fddbda56-cfb5-4baf-b92b-2df8fc742d21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_a00a5f46-63cd-4336-8f17-e2c27e0c7369" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_fddbda56-cfb5-4baf-b92b-2df8fc742d21" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_a00a5f46-63cd-4336-8f17-e2c27e0c7369" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostsAndExpensesAbstract"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_7bc62402-9bbd-4568-8499-6e3e27a5f052" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_7bc62402-9bbd-4568-8499-6e3e27a5f052" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_9646d56b-b3ad-4d74-90c7-a0a9c19a96e7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_9646d56b-b3ad-4d74-90c7-a0a9c19a96e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchandDevelopmentExpenseRelatedParty_0f8e124d-fe9c-4484-8992-fb74fa4cb54a" xlink:href="dyai-20191231.xsd#dyai_ResearchandDevelopmentExpenseRelatedParty"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:to="loc_dyai_ResearchandDevelopmentExpenseRelatedParty_0f8e124d-fe9c-4484-8992-fb74fa4cb54a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_05bfc365-4c08-47a5-b67e-2df55b9cd016" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_05bfc365-4c08-47a5-b67e-2df55b9cd016" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_1e87c7e7-4afc-4c4b-a03f-8f927fa70674" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_1e87c7e7-4afc-4c4b-a03f-8f927fa70674" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_1985228a-c969-4d94-8668-1f0102fa3a84" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostsAndExpenses"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_cb3cb0f8-69f0-4fa7-ba48-c09e20f787ac" xlink:to="loc_us-gaap_CostsAndExpenses_1985228a-c969-4d94-8668-1f0102fa3a84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_f168cf4d-960b-4876-917c-934f2995e5f3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_OperatingIncomeLoss_f168cf4d-960b-4876-917c-934f2995e5f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_134a3aa6-0dfa-4642-987e-b69e8487f7b6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_134a3aa6-0dfa-4642-987e-b69e8487f7b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossAttributableToParent_a80562b0-c723-4719-8931-d05241ad6604" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossAttributableToParent"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_IncomeLossAttributableToParent_a80562b0-c723-4719-8931-d05241ad6604" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_cddd1ec5-a0c4-4dd2-ad3e-203648eb1328" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_cddd1ec5-a0c4-4dd2-ad3e-203648eb1328" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_79ae4df7-da1c-4aef-b756-9a3b73a22609" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLoss"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_NetIncomeLoss_79ae4df7-da1c-4aef-b756-9a3b73a22609" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_254a7fe8-c4a7-4e1f-b246-eb7a0738fbe6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_254a7fe8-c4a7-4e1f-b246-eb7a0738fbe6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_abba6670-fe1a-4fd0-a175-051378a865cd" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_02f7fd21-171d-46f8-8653-7cfd9cfa8311" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_abba6670-fe1a-4fd0-a175-051378a865cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY" xlink:type="simple" xlink:href="dyai-20191231.xsd#CONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_287da0ab-7521-4401-abe3-ef3b3ec348ad" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_cf157030-013e-41d2-b871-04d0c1838f85" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_287da0ab-7521-4401-abe3-ef3b3ec348ad" xlink:to="loc_us-gaap_StatementTable_cf157030-013e-41d2-b871-04d0c1838f85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_5276480e-7cf7-44a8-a48f-9c852e936a15" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_cf157030-013e-41d2-b871-04d0c1838f85" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_5276480e-7cf7-44a8-a48f-9c852e936a15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_ef1cc687-a5af-4d64-9d90-be2369f0cde0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_5276480e-7cf7-44a8-a48f-9c852e936a15" xlink:to="loc_us-gaap_EquityComponentDomain_ef1cc687-a5af-4d64-9d90-be2369f0cde0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_7501a383-5ce4-474a-bdb5-cd98362d20c4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ef1cc687-a5af-4d64-9d90-be2369f0cde0" xlink:to="loc_us-gaap_CommonStockMember_7501a383-5ce4-474a-bdb5-cd98362d20c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockMember_2b8b8e65-1e50-41ba-973e-970a80c2131f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ef1cc687-a5af-4d64-9d90-be2369f0cde0" xlink:to="loc_us-gaap_TreasuryStockMember_2b8b8e65-1e50-41ba-973e-970a80c2131f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_9abb8f1a-11f2-4c53-be76-6767e96fd3a3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ef1cc687-a5af-4d64-9d90-be2369f0cde0" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_9abb8f1a-11f2-4c53-be76-6767e96fd3a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_df04774d-7ad0-4e2a-b872-90b50aba81d4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RetainedEarningsMember"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ef1cc687-a5af-4d64-9d90-be2369f0cde0" xlink:to="loc_us-gaap_RetainedEarningsMember_df04774d-7ad0-4e2a-b872-90b50aba81d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_f6381f15-4a9a-4bb5-b3b0-6ee83f61b2d1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementLineItems"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_cf157030-013e-41d2-b871-04d0c1838f85" xlink:to="loc_us-gaap_StatementLineItems_f6381f15-4a9a-4bb5-b3b0-6ee83f61b2d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_f6381f15-4a9a-4bb5-b3b0-6ee83f61b2d1" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_ae291b1f-feb8-42a5-85da-b103acf2ee91" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_CommonStockSharesIssued_ae291b1f-feb8-42a5-85da-b103acf2ee91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_d22d40f8-39f2-470a-99d1-337894e95a26" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_StockholdersEquity_d22d40f8-39f2-470a-99d1-337894e95a26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_6278a206-7f8e-4910-9116-b45d6cff60cf" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_6278a206-7f8e-4910-9116-b45d6cff60cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_154a71a0-c9f8-4af0-bff1-84e0a10e43d6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_154a71a0-c9f8-4af0-bff1-84e0a10e43d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_c6a713ab-e6aa-42ec-b4b9-e7fe368ad69a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_c6a713ab-e6aa-42ec-b4b9-e7fe368ad69a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_b3c6add1-3a4e-482d-a9d4-99bfcc3303c7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockSharesAcquired"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_b3c6add1-3a4e-482d-a9d4-99bfcc3303c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_9615a0d1-6c8e-43aa-a1a7-bd235944ca41" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_9615a0d1-6c8e-43aa-a1a7-bd235944ca41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_a5cecf9f-e400-486d-82a4-935c8455481c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLoss"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_NetIncomeLoss_a5cecf9f-e400-486d-82a4-935c8455481c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_193e75d1-db8b-43d8-8181-dd2fbbdc34f1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_CommonStockSharesIssued_193e75d1-db8b-43d8-8181-dd2fbbdc34f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_a215bc53-30b1-4251-b16f-fe4acd4b25dc" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_bf2624eb-4c9a-4c4e-af64-832d8ee8df92" xlink:to="loc_us-gaap_StockholdersEquity_a215bc53-30b1-4251-b16f-fe4acd4b25dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="simple" xlink:href="dyai-20191231.xsd#CONSOLIDATEDSTATEMENTSOFCASHFLOWS"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_3ac557ec-f70d-4e0c-bffc-3034d3d213cf" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_3ac557ec-f70d-4e0c-bffc-3034d3d213cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_0a36962e-a1a2-4463-bf92-63008cbb7f9d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLoss"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_3ac557ec-f70d-4e0c-bffc-3034d3d213cf" xlink:to="loc_us-gaap_NetIncomeLoss_0a36962e-a1a2-4463-bf92-63008cbb7f9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_ca1c0e53-7a65-4ddd-986c-7f7cf3131d46" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_3ac557ec-f70d-4e0c-bffc-3034d3d213cf" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_ca1c0e53-7a65-4ddd-986c-7f7cf3131d46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_4214a07a-34d5-47cb-b37c-a171b59726d9" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensation"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_ca1c0e53-7a65-4ddd-986c-7f7cf3131d46" xlink:to="loc_us-gaap_ShareBasedCompensation_4214a07a-34d5-47cb-b37c-a171b59726d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeAmortizationOfPremium_005de12a-eb8b-4e21-9934-035cd0b3781c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentIncomeAmortizationOfPremium"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_ca1c0e53-7a65-4ddd-986c-7f7cf3131d46" xlink:to="loc_us-gaap_InvestmentIncomeAmortizationOfPremium_005de12a-eb8b-4e21-9934-035cd0b3781c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_cac7af50-77b2-4de7-9bee-299b73b54595" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_ca1c0e53-7a65-4ddd-986c-7f7cf3131d46" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_cac7af50-77b2-4de7-9bee-299b73b54595" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_ca1c0e53-7a65-4ddd-986c-7f7cf3131d46" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_b046144a-6540-430d-a6b2-5b642c9f1512" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_b046144a-6540-430d-a6b2-5b642c9f1512" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_b8f6f4eb-9ec3-4ba6-ae75-22d9d737f277" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_b8f6f4eb-9ec3-4ba6-ae75-22d9d737f277" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_5e84c36a-2166-47f8-956f-706817da99b2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesReceivable"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_5e84c36a-2166-47f8-956f-706817da99b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_IncreaseDecreaseinPrepaidResearchandDevelopment_0d886c28-34d9-4585-9b69-0d6a2565aa33" xlink:href="dyai-20191231.xsd#dyai_IncreaseDecreaseinPrepaidResearchandDevelopment"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_dyai_IncreaseDecreaseinPrepaidResearchandDevelopment_0d886c28-34d9-4585-9b69-0d6a2565aa33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_e596a365-420e-46d6-bf13-1cb563c45f09" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_e596a365-420e-46d6-bf13-1cb563c45f09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_c8ea4535-866b-40a9-9545-b40cf50f8371" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_c8ea4535-866b-40a9-9545-b40cf50f8371" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_ccf9705d-820b-4f54-9121-336440d04c21" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_ccf9705d-820b-4f54-9121-336440d04c21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_3001993c-e305-46f1-95c4-f7850d2eeb0f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_3001993c-e305-46f1-95c4-f7850d2eeb0f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_c347ca4c-851c-4ff1-88a0-df616a5c5c60" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_623c4d6f-2b2c-4899-870e-d8fcd02ba1e7" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_c347ca4c-851c-4ff1-88a0-df616a5c5c60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_c24b1aa6-2b27-48f1-a241-c468bac063ae" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_3ac557ec-f70d-4e0c-bffc-3034d3d213cf" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_c24b1aa6-2b27-48f1-a241-c468bac063ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7dd20bdf-a183-43d3-b8f7-93030ba83727" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7dd20bdf-a183-43d3-b8f7-93030ba83727" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_2eb65f5f-e600-4cfb-b9b6-30a44e158772" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsToAcquireHeldToMaturitySecurities"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7dd20bdf-a183-43d3-b8f7-93030ba83727" xlink:to="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_2eb65f5f-e600-4cfb-b9b6-30a44e158772" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleAndMaturityOfHeldToMaturitySecurities_a9ef74f0-1986-4e19-bb2d-7008d3dd9c1a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromSaleAndMaturityOfHeldToMaturitySecurities"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7dd20bdf-a183-43d3-b8f7-93030ba83727" xlink:to="loc_us-gaap_ProceedsFromSaleAndMaturityOfHeldToMaturitySecurities_a9ef74f0-1986-4e19-bb2d-7008d3dd9c1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_31c3c340-fc69-46cd-aa88-fedb0e6bcd49" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7dd20bdf-a183-43d3-b8f7-93030ba83727" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_31c3c340-fc69-46cd-aa88-fedb0e6bcd49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_4d45dd58-432c-4294-a3d6-6c758c14bf43" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_4d45dd58-432c-4294-a3d6-6c758c14bf43" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_22aebf86-8159-476e-9f51-f8a5560d76f5" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_4d45dd58-432c-4294-a3d6-6c758c14bf43" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_22aebf86-8159-476e-9f51-f8a5560d76f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_2c1a2643-b87b-4ea2-abf8-0a22c0c904a8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_4d45dd58-432c-4294-a3d6-6c758c14bf43" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_2c1a2643-b87b-4ea2-abf8-0a22c0c904a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1f43195e-78ac-493e-8b09-95579c81352c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_4d45dd58-432c-4294-a3d6-6c758c14bf43" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1f43195e-78ac-493e-8b09-95579c81352c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_92be63ad-6295-4ada-b4f5-897425a6aec1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_92be63ad-6295-4ada-b4f5-897425a6aec1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_929a51a8-6ffa-4b1d-ad77-dc15ff558a4a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_929a51a8-6ffa-4b1d-ad77-dc15ff558a4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_f991a54c-e8af-4ab6-b761-9231f085d4ea" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_f991a54c-e8af-4ab6-b761-9231f085d4ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_02770cea-d30a-4320-8621-0f3b621f9643" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_02770cea-d30a-4320-8621-0f3b621f9643" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_6a2c61ed-e358-4018-8ec8-bde8c94f7906" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_729e8220-802d-4f5a-b4c8-bd867e172404" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_6a2c61ed-e358-4018-8ec8-bde8c94f7906" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIncomeTaxRefunds_aa6b2d2c-e3ef-49e6-8251-42a740e6dc1e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromIncomeTaxRefunds"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_6a2c61ed-e358-4018-8ec8-bde8c94f7906" xlink:to="loc_us-gaap_ProceedsFromIncomeTaxRefunds_aa6b2d2c-e3ef-49e6-8251-42a740e6dc1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPolicies"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPolicies" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_b46429ed-f30b-499b-aedc-1c91b774cc78" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessDescriptionAndAccountingPoliciesTextBlock_ac53446b-4db1-4fa4-b239-b9168f54a535" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessDescriptionAndAccountingPoliciesTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_b46429ed-f30b-499b-aedc-1c91b774cc78" xlink:to="loc_us-gaap_BusinessDescriptionAndAccountingPoliciesTextBlock_ac53446b-4db1-4fa4-b239-b9168f54a535" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesPolicies"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_9c25bb9c-671f-4fa6-bc7b-5e0dccf9a46b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_9c25bb9c-671f-4fa6-bc7b-5e0dccf9a46b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_9ae53c9f-504c-4296-8e2b-43cbd6536023" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UseOfEstimates"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_UseOfEstimates_9ae53c9f-504c-4296-8e2b-43cbd6536023" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskCreditRisk_db89e8ac-1d9f-46eb-b6d1-997aa683e084" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskCreditRisk"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_ConcentrationRiskCreditRisk_db89e8ac-1d9f-46eb-b6d1-997aa683e084" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_d484b694-9665-45ee-91f1-e8c25b93fb17" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_d484b694-9665-45ee-91f1-e8c25b93fb17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentPolicyTextBlock_a2e9d44f-cd8d-4fd7-8069-d9f395f33f57" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentPolicyTextBlock"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_InvestmentPolicyTextBlock_a2e9d44f-cd8d-4fd7-8069-d9f395f33f57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesTradeAndOtherAccountsReceivableAllowanceForDoubtfulAccountsPolicy_94fc1b28-114e-45f2-b8f5-1a7a91b8d966" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ReceivablesTradeAndOtherAccountsReceivableAllowanceForDoubtfulAccountsPolicy"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_ReceivablesTradeAndOtherAccountsReceivableAllowanceForDoubtfulAccountsPolicy_94fc1b28-114e-45f2-b8f5-1a7a91b8d966" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentsPolicy_b53eeed4-8597-4249-8901-4fc30dad1058" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsPolicy"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_EquityMethodInvestmentsPolicy_b53eeed4-8597-4249-8901-4fc30dad1058" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_ceb22489-435b-4915-86a5-d3be784d6c71" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_ceb22489-435b-4915-86a5-d3be784d6c71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_8e4a6061-cf91-4dc1-9229-c9e2da1ac417" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_8e4a6061-cf91-4dc1-9229-c9e2da1ac417" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_429b4fb9-8edd-4b9a-b6d2-f8c2e09782fd" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_429b4fb9-8edd-4b9a-b6d2-f8c2e09782fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_3a019165-60de-484a-8874-42058c91a5aa" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock"/>
<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_3a019165-60de-484a-8874-42058c91a5aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_aa4d7908-5ade-4a15-bac6-6d9d863c00f0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock"/>
<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_aa4d7908-5ade-4a15-bac6-6d9d863c00f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomePolicyPolicyTextBlock_7013e374-f409-407b-84e4-6074956f92a5" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ComprehensiveIncomePolicyPolicyTextBlock"/>
<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_ComprehensiveIncomePolicyPolicyTextBlock_7013e374-f409-407b-84e4-6074956f92a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_ea7fed55-e6c9-49f7-8009-0729e5a3c7fe" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy"/>
<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_ea7fed55-e6c9-49f7-8009-0729e5a3c7fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_b35149d1-9d76-4456-8da2-bec3baac57dd" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerSharePolicyTextBlock"/>
<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_b35149d1-9d76-4456-8da2-bec3baac57dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_78f9a7cb-72a0-4cdf-9f7d-4bb6bfb0a442" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_12e539c7-236a-4982-ab11-6be34ab32045" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_78f9a7cb-72a0-4cdf-9f7d-4bb6bfb0a442" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesTables"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesTables" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_4d933092-1fa8-4d7f-9a56-56da1661ead7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_f57bb547-2ca2-4009-9e9a-0f5a71012137" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4d933092-1fa8-4d7f-9a56-56da1661ead7" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_f57bb547-2ca2-4009-9e9a-0f5a71012137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock_00497903-25a4-4387-ae8a-7c47e74fb183" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4d933092-1fa8-4d7f-9a56-56da1661ead7" xlink:to="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock_00497903-25a4-4387-ae8a-7c47e74fb183" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_8256b2c8-5360-4152-976c-6b1ef113f43d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4d933092-1fa8-4d7f-9a56-56da1661ead7" xlink:to="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_8256b2c8-5360-4152-976c-6b1ef113f43d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_25c549a2-50d8-4c68-8b6e-a11921ef7c6b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4d933092-1fa8-4d7f-9a56-56da1661ead7" xlink:to="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_25c549a2-50d8-4c68-8b6e-a11921ef7c6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ScheduleofResearchandDevelopmentCostsTableTextBlock_2fce1ab0-1d4e-458b-8791-dcad42ddfe87" xlink:href="dyai-20191231.xsd#dyai_ScheduleofResearchandDevelopmentCostsTableTextBlock"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4d933092-1fa8-4d7f-9a56-56da1661ead7" xlink:to="loc_dyai_ScheduleofResearchandDevelopmentCostsTableTextBlock_2fce1ab0-1d4e-458b-8791-dcad42ddfe87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesTextualDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesTextualDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesTextualDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_0721dbc6-bcd6-4ec0-ba58-4f21ecc87c06" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_0721dbc6-bcd6-4ec0-ba58-4f21ecc87c06" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_a2a80cf0-1b88-4390-9f89-07c4cf33f51e" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:to="loc_srt_CounterpartyNameAxis_a2a80cf0-1b88-4390-9f89-07c4cf33f51e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_cc46c229-036a-40ab-9afe-22e568ec933d" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_a2a80cf0-1b88-4390-9f89-07c4cf33f51e" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_cc46c229-036a-40ab-9afe-22e568ec933d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DuPontDaniscoMember_380e6b28-f4bd-4b59-88bc-6adb6140a9e7" xlink:href="dyai-20191231.xsd#dyai_DuPontDaniscoMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_cc46c229-036a-40ab-9afe-22e568ec933d" xlink:to="loc_dyai_DuPontDaniscoMember_380e6b28-f4bd-4b59-88bc-6adb6140a9e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ContractResearchOrganizationsMember_6ceea767-8cf9-4030-a1dd-9f95231d58c7" xlink:href="dyai-20191231.xsd#dyai_ContractResearchOrganizationsMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_cc46c229-036a-40ab-9afe-22e568ec933d" xlink:to="loc_dyai_ContractResearchOrganizationsMember_6ceea767-8cf9-4030-a1dd-9f95231d58c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_a1ded76f-6476-4a26-be9f-3a59f0f6f665" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_a1ded76f-6476-4a26-be9f-3a59f0f6f665" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_24a27088-f36a-4dba-b6b3-fe2b38d1e4c6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_a1ded76f-6476-4a26-be9f-3a59f0f6f665" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_24a27088-f36a-4dba-b6b3-fe2b38d1e4c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_IndustrialTechnologyBusinessMember_d67b262c-b210-494b-a956-abdb159d8f21" xlink:href="dyai-20191231.xsd#dyai_IndustrialTechnologyBusinessMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_24a27088-f36a-4dba-b6b3-fe2b38d1e4c6" xlink:to="loc_dyai_IndustrialTechnologyBusinessMember_d67b262c-b210-494b-a956-abdb159d8f21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_157dddef-6d26-4421-90b8-4634bbf90958" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_StatementGeographicalAxis"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:to="loc_srt_StatementGeographicalAxis_157dddef-6d26-4421-90b8-4634bbf90958" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_92e0f086-bfb5-47ff-ad3d-f2e6a32cf358" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_SegmentGeographicalDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_157dddef-6d26-4421-90b8-4634bbf90958" xlink:to="loc_srt_SegmentGeographicalDomain_92e0f086-bfb5-47ff-ad3d-f2e6a32cf358" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember_7ead9165-c169-469d-8a21-a24bd661cf40" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NonUsMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_92e0f086-bfb5-47ff-ad3d-f2e6a32cf358" xlink:to="loc_us-gaap_NonUsMember_7ead9165-c169-469d-8a21-a24bd661cf40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_country_US_46ee0bfe-238a-4fb9-ab48-cdcc9f30a81e" xlink:href="http://xbrl.sec.gov/country/2017/country-2017-01-31.xsd#country_US"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_92e0f086-bfb5-47ff-ad3d-f2e6a32cf358" xlink:to="loc_country_US_46ee0bfe-238a-4fb9-ab48-cdcc9f30a81e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_47d074c6-e3d0-4546-b063-11a12f2f9c87" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_47d074c6-e3d0-4546-b063-11a12f2f9c87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_c89c24a1-bd56-4e23-b4dc-5bc1fa35e776" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_47d074c6-e3d0-4546-b063-11a12f2f9c87" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_c89c24a1-bd56-4e23-b4dc-5bc1fa35e776" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerConcentrationRiskMember_47b2b741-2831-4135-a6b5-6c6d8a734600" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CustomerConcentrationRiskMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_c89c24a1-bd56-4e23-b4dc-5bc1fa35e776" xlink:to="loc_us-gaap_CustomerConcentrationRiskMember_47b2b741-2831-4135-a6b5-6c6d8a734600" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_8bad205c-1d0d-4019-8bb0-ae2b0300082f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_8bad205c-1d0d-4019-8bb0-ae2b0300082f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_af7fede7-83f9-44d2-a692-e2cd680c4f8f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_8bad205c-1d0d-4019-8bb0-ae2b0300082f" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_af7fede7-83f9-44d2-a692-e2cd680c4f8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SalesRevenueNetMember_63638213-02cb-4af9-a6fd-0e921d62879b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SalesRevenueNetMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_af7fede7-83f9-44d2-a692-e2cd680c4f8f" xlink:to="loc_us-gaap_SalesRevenueNetMember_63638213-02cb-4af9-a6fd-0e921d62879b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableMember_bfc486d5-c474-46d4-8aad-d0096b487a31" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_af7fede7-83f9-44d2-a692-e2cd680c4f8f" xlink:to="loc_us-gaap_AccountsReceivableMember_bfc486d5-c474-46d4-8aad-d0096b487a31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableMember_68a88427-767c-4ae3-9fe4-e10c5f398130" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableMember"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_af7fede7-83f9-44d2-a692-e2cd680c4f8f" xlink:to="loc_us-gaap_AccountsPayableMember_68a88427-767c-4ae3-9fe4-e10c5f398130" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8af089f8-907d-4474-93a0-e969e626b9fc" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_NumberOfResearchOrganizationPerformingServiceUnderContract_d731c002-019c-49a9-aad1-17d3152f5e7c" xlink:href="dyai-20191231.xsd#dyai_NumberOfResearchOrganizationPerformingServiceUnderContract"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_dyai_NumberOfResearchOrganizationPerformingServiceUnderContract_d731c002-019c-49a9-aad1-17d3152f5e7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSalesOfBusinessAffiliateAndProductiveAssets_234003ac-6054-4dc1-9090-338baf6d0103" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromSalesOfBusinessAffiliateAndProductiveAssets"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_ProceedsFromSalesOfBusinessAffiliateAndProductiveAssets_234003ac-6054-4dc1-9090-338baf6d0103" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_b4985ce4-46f0-4597-8acf-7d8911ccde0f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_NumberOfOperatingSegments_b4985ce4-46f0-4597-8acf-7d8911ccde0f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ConcentrationRiskNumberofCustomers_92287df4-b31a-471d-958b-4b258cd6cc03" xlink:href="dyai-20191231.xsd#dyai_ConcentrationRiskNumberofCustomers"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_dyai_ConcentrationRiskNumberofCustomers_92287df4-b31a-471d-958b-4b258cd6cc03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_2f203fed-4296-4dc6-bcf8-addf7909cc32" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskPercentage1"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_2f203fed-4296-4dc6-bcf8-addf7909cc32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_d589e17d-1794-49f2-bc5f-c079a8bde1f0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_d589e17d-1794-49f2-bc5f-c079a8bde1f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNet_db55e4c2-3b24-406a-8789-d5f6c3edee27" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableNet"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_AccountsReceivableNet_db55e4c2-3b24-406a-8789-d5f6c3edee27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrentAndNoncurrent_9b8297a5-d49c-481f-896a-2d117c1683b1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableCurrentAndNoncurrent"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_AccountsPayableCurrentAndNoncurrent_9b8297a5-d49c-481f-896a-2d117c1683b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_2cb055d5-6455-4a0a-9030-403ac5a4242b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_2cb055d5-6455-4a0a-9030-403ac5a4242b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_b919b010-9462-41f7-9ec2-b3cffd7be947" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_c4cc78bb-99a5-4e70-9fc6-ab13b21b5e55" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_b919b010-9462-41f7-9ec2-b3cffd7be947" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesAccountsReceivableDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesAccountsReceivableDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesAccountsReceivableDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_a89127b5-ec89-4d3a-950b-82210059708b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_82eeadd9-6015-4890-8631-188f8ce82c4f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_a89127b5-ec89-4d3a-950b-82210059708b" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_82eeadd9-6015-4890-8631-188f8ce82c4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesLoansAndFinancingReceivablesByBillingStatusTypeAxis_646db54b-41be-46bb-afd7-f1965afd9dae" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivablesByBillingStatusTypeAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_82eeadd9-6015-4890-8631-188f8ce82c4f" xlink:to="loc_us-gaap_AccountsNotesLoansAndFinancingReceivablesByBillingStatusTypeAxis_646db54b-41be-46bb-afd7-f1965afd9dae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesBillingStatusDomain_75caaa53-ac0f-4ed9-ba56-d4180fcc4e55" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ReceivablesBillingStatusDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesLoansAndFinancingReceivablesByBillingStatusTypeAxis_646db54b-41be-46bb-afd7-f1965afd9dae" xlink:to="loc_us-gaap_ReceivablesBillingStatusDomain_75caaa53-ac0f-4ed9-ba56-d4180fcc4e55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BilledRevenuesMember_1ffb7aa9-4819-4003-953e-0bb01dc008c3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BilledRevenuesMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesBillingStatusDomain_75caaa53-ac0f-4ed9-ba56-d4180fcc4e55" xlink:to="loc_us-gaap_BilledRevenuesMember_1ffb7aa9-4819-4003-953e-0bb01dc008c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnbilledRevenuesMember_7e0b49c4-9a2c-4e06-a15a-61a1423c40a9" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UnbilledRevenuesMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesBillingStatusDomain_75caaa53-ac0f-4ed9-ba56-d4180fcc4e55" xlink:to="loc_us-gaap_UnbilledRevenuesMember_7e0b49c4-9a2c-4e06-a15a-61a1423c40a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_5f6b2b2b-e4ea-4e1c-a7f8-91b23f8825ee" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_82eeadd9-6015-4890-8631-188f8ce82c4f" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_5f6b2b2b-e4ea-4e1c-a7f8-91b23f8825ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_e4ba64a2-38ef-4cfa-92ae-f0f7d0e3b299" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_5f6b2b2b-e4ea-4e1c-a7f8-91b23f8825ee" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_e4ba64a2-38ef-4cfa-92ae-f0f7d0e3b299" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesPrepaidExpensesandOtherCurrentAssetsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesPrepaidExpensesandOtherCurrentAssetsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesPrepaidExpensesandOtherCurrentAssetsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_3abb4b11-609e-49ec-8474-e5bcf4016bfb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidInsurance_911c3017-1af6-4ce7-991b-c95a43f73044" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PrepaidInsurance"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3abb4b11-609e-49ec-8474-e5bcf4016bfb" xlink:to="loc_us-gaap_PrepaidInsurance_911c3017-1af6-4ce7-991b-c95a43f73044" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPrepaidExpenseCurrent_c9f85b4d-c2f5-4f89-9d33-e622b664474b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherPrepaidExpenseCurrent"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3abb4b11-609e-49ec-8474-e5bcf4016bfb" xlink:to="loc_us-gaap_OtherPrepaidExpenseCurrent_c9f85b4d-c2f5-4f89-9d33-e622b664474b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidTaxes_dd0f8c19-e247-4998-8b64-aea0020259a0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PrepaidTaxes"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3abb4b11-609e-49ec-8474-e5bcf4016bfb" xlink:to="loc_us-gaap_PrepaidTaxes_dd0f8c19-e247-4998-8b64-aea0020259a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_9c723449-ac6f-47c0-9233-308f5eaa7f52" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3abb4b11-609e-49ec-8474-e5bcf4016bfb" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_9c723449-ac6f-47c0-9233-308f5eaa7f52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesAccountsPayableDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesAccountsPayableDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesAccountsPayableDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_3c9b6852-9fc7-4ea5-bbc6-48624166dc18" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentInProcessCurrent_97f01d0b-5023-4b55-9331-20c7b914bc3b" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentInProcessCurrent"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3c9b6852-9fc7-4ea5-bbc6-48624166dc18" xlink:to="loc_dyai_ResearchAndDevelopmentInProcessCurrent_97f01d0b-5023-4b55-9331-20c7b914bc3b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedProfessionalFeesCurrent_93517514-4df1-4da6-ad74-f81108012cff" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccruedProfessionalFeesCurrent"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3c9b6852-9fc7-4ea5-bbc6-48624166dc18" xlink:to="loc_us-gaap_AccruedProfessionalFeesCurrent_93517514-4df1-4da6-ad74-f81108012cff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableOtherCurrent_15c44e56-cb33-4381-8f58-246836bf6364" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableOtherCurrent"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3c9b6852-9fc7-4ea5-bbc6-48624166dc18" xlink:to="loc_us-gaap_AccountsPayableOtherCurrent_15c44e56-cb33-4381-8f58-246836bf6364" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_92d97e4e-b4e0-4aee-bc2f-fe1b6c3cc8eb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3c9b6852-9fc7-4ea5-bbc6-48624166dc18" xlink:to="loc_us-gaap_AccountsPayableCurrent_92d97e4e-b4e0-4aee-bc2f-fe1b6c3cc8eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesAccruedExpensesDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesAccruedExpensesDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesAccruedExpensesDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_ba1a758d-2424-48d6-97f4-009b18a622ed" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_2def3951-ee4d-48f2-9ca5-b1cb0facadbf" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_ba1a758d-2424-48d6-97f4-009b18a622ed" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_2def3951-ee4d-48f2-9ca5-b1cb0facadbf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_AccruedResearchandDevelopmentinProcessCurrent_2586fb6e-7691-4f41-838e-b865574b89e3" xlink:href="dyai-20191231.xsd#dyai_AccruedResearchandDevelopmentinProcessCurrent"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_ba1a758d-2424-48d6-97f4-009b18a622ed" xlink:to="loc_dyai_AccruedResearchandDevelopmentinProcessCurrent_2586fb6e-7691-4f41-838e-b865574b89e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_e20a8573-962d-43b3-8be6-a876121ff922" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_ba1a758d-2424-48d6-97f4-009b18a622ed" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_e20a8573-962d-43b3-8be6-a876121ff922" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_97f6e3d5-9e1c-4a98-b04a-ca1ff9fe701f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_ba1a758d-2424-48d6-97f4-009b18a622ed" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_97f6e3d5-9e1c-4a98-b04a-ca1ff9fe701f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesResearchandDevelopmentCostsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#OrganizationandSummaryofSignificantAccountingPoliciesResearchandDevelopmentCostsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/OrganizationandSummaryofSignificantAccountingPoliciesResearchandDevelopmentCostsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_f6b1dcb9-9260-4879-a283-d2c4a1b611c1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentExpenseOutsideContractedServices_07a45d83-ed18-447d-a69c-831350d777ee" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentExpenseOutsideContractedServices"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f6b1dcb9-9260-4879-a283-d2c4a1b611c1" xlink:to="loc_dyai_ResearchAndDevelopmentExpenseOutsideContractedServices_07a45d83-ed18-447d-a69c-831350d777ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentExpenseContractedServicesRelatedParty_cb957e55-2d74-4866-a1b7-705602ac65da" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentExpenseContractedServicesRelatedParty"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f6b1dcb9-9260-4879-a283-d2c4a1b611c1" xlink:to="loc_dyai_ResearchAndDevelopmentExpenseContractedServicesRelatedParty_cb957e55-2d74-4866-a1b7-705602ac65da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentExpensePersonnelRelatedCosts_67e1181e-0483-49ce-ae67-ba4f289e8065" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentExpensePersonnelRelatedCosts"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f6b1dcb9-9260-4879-a283-d2c4a1b611c1" xlink:to="loc_dyai_ResearchAndDevelopmentExpensePersonnelRelatedCosts_67e1181e-0483-49ce-ae67-ba4f289e8065" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentExpenseFacilitiesOverheadandOther_36297e01-45da-4160-afcb-fd89837ab9e1" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentExpenseFacilitiesOverheadandOther"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f6b1dcb9-9260-4879-a283-d2c4a1b611c1" xlink:to="loc_dyai_ResearchAndDevelopmentExpenseFacilitiesOverheadandOther_36297e01-45da-4160-afcb-fd89837ab9e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentExpenseIncludingRelatedParty_b49e5afa-ae8a-4aa8-88c1-737d2303f314" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentExpenseIncludingRelatedParty"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_f6b1dcb9-9260-4879-a283-d2c4a1b611c1" xlink:to="loc_dyai_ResearchAndDevelopmentExpenseIncludingRelatedParty_b49e5afa-ae8a-4aa8-88c1-737d2303f314" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CashCashEquivalentandInvestments" xlink:type="simple" xlink:href="dyai-20191231.xsd#CashCashEquivalentandInvestments"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CashCashEquivalentandInvestments" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAbstract_d4b45949-70fb-42dc-9beb-93eed5c28e12" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndMarketableSecuritiesTextBlock_1ef09216-d7f6-442d-a440-75b143bf6648" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsAndMarketableSecuritiesTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_d4b45949-70fb-42dc-9beb-93eed5c28e12" xlink:to="loc_us-gaap_CashCashEquivalentsAndMarketableSecuritiesTextBlock_1ef09216-d7f6-442d-a440-75b143bf6648" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CashCashEquivalentandInvestmentsTables" xlink:type="simple" xlink:href="dyai-20191231.xsd#CashCashEquivalentandInvestmentsTables"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CashCashEquivalentandInvestmentsTables" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAbstract_6a55d66e-1e26-4f41-9e44-9bcd9fa9fdfa" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock_a0d5c08c-10ee-4df0-b380-f9f9832e9524" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_6a55d66e-1e26-4f41-9e44-9bcd9fa9fdfa" xlink:to="loc_us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock_a0d5c08c-10ee-4df0-b380-f9f9832e9524" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CashCashEquivalentandInvestmentsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#CashCashEquivalentandInvestmentsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CashCashEquivalentandInvestmentsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAbstract_a4ca0815-e384-4e2b-967e-d329829353e7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_d59f4c1c-7171-4260-8336-20ddac651dff" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAbstract_a4ca0815-e384-4e2b-967e-d329829353e7" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_d59f4c1c-7171-4260-8336-20ddac651dff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_ad969e5c-5c18-4eb0-b9d6-6b965690eda2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_d59f4c1c-7171-4260-8336-20ddac651dff" xlink:to="loc_us-gaap_FinancialInstrumentAxis_ad969e5c-5c18-4eb0-b9d6-6b965690eda2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_251b9cf6-3ee0-4fe6-9bb4-18413616ed59" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_ad969e5c-5c18-4eb0-b9d6-6b965690eda2" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_251b9cf6-3ee0-4fe6-9bb4-18413616ed59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_83033cd8-bdfc-4338-9889-1177dd7d5111" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CorporateDebtSecuritiesMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_251b9cf6-3ee0-4fe6-9bb4-18413616ed59" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_83033cd8-bdfc-4338-9889-1177dd7d5111" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAxis_4eb104bb-c0ab-4e77-b257-a989340a03ce" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_d59f4c1c-7171-4260-8336-20ddac651dff" xlink:to="loc_us-gaap_CashAndCashEquivalentsAxis_4eb104bb-c0ab-4e77-b257-a989340a03ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_1bcdd29b-f89e-4f12-ac0e-496f7965c21f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAxis_4eb104bb-c0ab-4e77-b257-a989340a03ce" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_1bcdd29b-f89e-4f12-ac0e-496f7965c21f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashMember_ef04f2a1-4701-420f-a8f9-4eafa544a2a3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_1bcdd29b-f89e-4f12-ac0e-496f7965c21f" xlink:to="loc_us-gaap_CashMember_ef04f2a1-4701-420f-a8f9-4eafa544a2a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_2187d2a1-4967-40cb-9e40-9ee1919a63a3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MoneyMarketFundsMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_1bcdd29b-f89e-4f12-ac0e-496f7965c21f" xlink:to="loc_us-gaap_MoneyMarketFundsMember_2187d2a1-4967-40cb-9e40-9ee1919a63a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_5ef6bad6-ac9a-4bf7-820e-513b0b15274c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_d59f4c1c-7171-4260-8336-20ddac651dff" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_5ef6bad6-ac9a-4bf7-820e-513b0b15274c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ad427426-c665-45cc-a6e7-cb3e46b7ce11" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_5ef6bad6-ac9a-4bf7-820e-513b0b15274c" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ad427426-c665-45cc-a6e7-cb3e46b7ce11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_7b708ad9-a35d-4a73-8fe4-3650483a5405" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ad427426-c665-45cc-a6e7-cb3e46b7ce11" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_7b708ad9-a35d-4a73-8fe4-3650483a5405" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_1f41f8d0-5cdc-4158-b21a-91b965720344" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ad427426-c665-45cc-a6e7-cb3e46b7ce11" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_1f41f8d0-5cdc-4158-b21a-91b965720344" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_d59f4c1c-7171-4260-8336-20ddac651dff" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_67d9911c-edcc-4232-8bf3-eb62cbaddf47" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_67d9911c-edcc-4232-8bf3-eb62cbaddf47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DebtSecuritiesHeldtomaturityFairValueCurrent_f561a993-b994-4299-a2b2-99b17aacaf23" xlink:href="dyai-20191231.xsd#dyai_DebtSecuritiesHeldtomaturityFairValueCurrent"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_DebtSecuritiesHeldtomaturityFairValueCurrent_f561a993-b994-4299-a2b2-99b17aacaf23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedGainCurrent_cc36c689-e4ae-458d-83b3-2cbd4ee53661" xlink:href="dyai-20191231.xsd#dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedGainCurrent"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedGainCurrent_cc36c689-e4ae-458d-83b3-2cbd4ee53661" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedLossCurrent_64ce7b98-2ef2-4a53-9d31-85ab8cb88194" xlink:href="dyai-20191231.xsd#dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedLossCurrent"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedLossCurrent_64ce7b98-2ef2-4a53-9d31-85ab8cb88194" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesCurrent_acf8ec3e-eeb0-465a-aa9b-e9272159b155" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_HeldToMaturitySecuritiesCurrent"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesCurrent_acf8ec3e-eeb0-465a-aa9b-e9272159b155" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DebtSecuritiesHeldtomaturityFairValueNoncurrent_eea62223-758e-40bd-a6d1-01113ca5e08b" xlink:href="dyai-20191231.xsd#dyai_DebtSecuritiesHeldtomaturityFairValueNoncurrent"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_DebtSecuritiesHeldtomaturityFairValueNoncurrent_eea62223-758e-40bd-a6d1-01113ca5e08b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedGainNoncurrent_b2925394-b502-40ea-9393-ab60fc4a123b" xlink:href="dyai-20191231.xsd#dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedGainNoncurrent"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedGainNoncurrent_b2925394-b502-40ea-9393-ab60fc4a123b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedLossNoncurrent_9ba4289e-8392-4f99-9028-47adf4dedf21" xlink:href="dyai-20191231.xsd#dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedLossNoncurrent"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_DebtSecuritiesHeldtomaturityAccumulatedUnrecognizedLossNoncurrent_9ba4289e-8392-4f99-9028-47adf4dedf21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesNoncurrent_a8453416-bb9c-41d4-8305-71b797460e3c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_HeldToMaturitySecuritiesNoncurrent"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesNoncurrent_a8453416-bb9c-41d4-8305-71b797460e3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsAndCash_93b98671-5186-4c56-b39a-eef98768d8b1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentsAndCash"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_us-gaap_InvestmentsAndCash_93b98671-5186-4c56-b39a-eef98768d8b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_50543adc-0329-487f-9d30-6673b4d2cc49" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_50543adc-0329-487f-9d30-6673b4d2cc49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_6c9bccfc-ad35-4987-8d0a-98be283fb7f8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_6c9bccfc-ad35-4987-8d0a-98be283fb7f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_InvestmentsandCashAmortizedCost_5772dcc9-153b-42b3-9181-145dd34e1ae6" xlink:href="dyai-20191231.xsd#dyai_InvestmentsandCashAmortizedCost"/>
<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_InvestmentsandCashAmortizedCost_5772dcc9-153b-42b3-9181-145dd34e1ae6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DebtSecuritiesHeldtomaturityPremiumPaidonPurchase_cb540754-abdb-4906-9a16-5682da470264" xlink:href="dyai-20191231.xsd#dyai_DebtSecuritiesHeldtomaturityPremiumPaidonPurchase"/>
<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_ded1652e-8c94-4b7e-8b58-340c841220d2" xlink:to="loc_dyai_DebtSecuritiesHeldtomaturityPremiumPaidonPurchase_cb540754-abdb-4906-9a16-5682da470264" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ResearchandCollaborationAgreements" xlink:type="simple" xlink:href="dyai-20191231.xsd#ResearchandCollaborationAgreements"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ResearchandCollaborationAgreements" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAbstract_af4dcc3f-fe91-485a-b0c2-1cda7c484a53" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_957166b0-6a6d-4238-add4-a662bef8086f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentAbstract_af4dcc3f-fe91-485a-b0c2-1cda7c484a53" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_957166b0-6a6d-4238-add4-a662bef8086f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ResearchCollaborationandSublicensingAgreementsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ResearchCollaborationandSublicensingAgreementsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ResearchCollaborationandSublicensingAgreementsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentAbstract_a0b484b2-519c-4c32-bf9a-32976c55d0f3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentAbstract_a0b484b2-519c-4c32-bf9a-32976c55d0f3" xlink:to="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_6833ceaa-0cac-418f-b42c-924d83468dff" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:to="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_6833ceaa-0cac-418f-b42c-924d83468dff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProjectMember_9490c304-7055-41a6-b783-e9626bfc1c26" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProjectMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_6833ceaa-0cac-418f-b42c-924d83468dff" xlink:to="loc_us-gaap_ProjectMember_9490c304-7055-41a6-b783-e9626bfc1c26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchServicesAgreementMember_66ca9311-8be6-47b4-8ee0-faca8575e9a1" xlink:href="dyai-20191231.xsd#dyai_ResearchServicesAgreementMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProjectMember_9490c304-7055-41a6-b783-e9626bfc1c26" xlink:to="loc_dyai_ResearchServicesAgreementMember_66ca9311-8be6-47b4-8ee0-faca8575e9a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ServiceFrameworkAgreementMember_de18e18b-9011-48c6-ba4c-93d29f923c43" xlink:href="dyai-20191231.xsd#dyai_ServiceFrameworkAgreementMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProjectMember_9490c304-7055-41a6-b783-e9626bfc1c26" xlink:to="loc_dyai_ServiceFrameworkAgreementMember_de18e18b-9011-48c6-ba4c-93d29f923c43" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_OwnershipAxis_ffae3086-6e1d-4e49-9231-db3bbfe689dc" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_OwnershipAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:to="loc_srt_OwnershipAxis_ffae3086-6e1d-4e49-9231-db3bbfe689dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_OwnershipDomain_2bb9a274-129a-41a7-8c77-9b4f598827fd" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_OwnershipDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_OwnershipAxis_ffae3086-6e1d-4e49-9231-db3bbfe689dc" xlink:to="loc_srt_OwnershipDomain_2bb9a274-129a-41a7-8c77-9b4f598827fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_BDIHoldingsMember_91ab8d18-dddb-4598-9c08-0e21cbe2bf98" xlink:href="dyai-20191231.xsd#dyai_BDIHoldingsMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_OwnershipDomain_2bb9a274-129a-41a7-8c77-9b4f598827fd" xlink:to="loc_dyai_BDIHoldingsMember_91ab8d18-dddb-4598-9c08-0e21cbe2bf98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_VLPbioMember_21fffdf3-de02-45ac-ba7d-ddc1544be202" xlink:href="dyai-20191231.xsd#dyai_VLPbioMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_OwnershipDomain_2bb9a274-129a-41a7-8c77-9b4f598827fd" xlink:to="loc_dyai_VLPbioMember_21fffdf3-de02-45ac-ba7d-ddc1544be202" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_BDIMember_ace45fc2-b40c-4e13-9e4d-afaabe2f95d1" xlink:href="dyai-20191231.xsd#dyai_BDIMember"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_OwnershipDomain_2bb9a274-129a-41a7-8c77-9b4f598827fd" xlink:to="loc_dyai_BDIMember_ace45fc2-b40c-4e13-9e4d-afaabe2f95d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_d8cec481-3dbe-4f62-b110-e39c9ea55bc9" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:to="loc_us-gaap_TypeOfArrangementAxis_d8cec481-3dbe-4f62-b110-e39c9ea55bc9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_21d0ed18-acbf-4d0f-9533-0524565553ce" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_d8cec481-3dbe-4f62-b110-e39c9ea55bc9" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_21d0ed18-acbf-4d0f-9533-0524565553ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementMember_91a608c4-0694-4c8e-846f-7945716bd6af" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CollaborativeArrangementMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_21d0ed18-acbf-4d0f-9533-0524565553ce" xlink:to="loc_us-gaap_CollaborativeArrangementMember_91a608c4-0694-4c8e-846f-7945716bd6af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_224076ef-11f7-4103-9943-e86d76cde566" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeAxis"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:to="loc_srt_RangeAxis_224076ef-11f7-4103-9943-e86d76cde566" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_3970ddbf-25d2-4ee1-839c-a4fe5746aab1" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_224076ef-11f7-4103-9943-e86d76cde566" xlink:to="loc_srt_RangeMember_3970ddbf-25d2-4ee1-839c-a4fe5746aab1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_9d9d63e6-3445-4a6e-9792-1d06a917163a" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MinimumMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_3970ddbf-25d2-4ee1-839c-a4fe5746aab1" xlink:to="loc_srt_MinimumMember_9d9d63e6-3445-4a6e-9792-1d06a917163a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_06a28412-2461-4b85-a458-d95685b19fcc" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MaximumMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_3970ddbf-25d2-4ee1-839c-a4fe5746aab1" xlink:to="loc_srt_MaximumMember_06a28412-2461-4b85-a458-d95685b19fcc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_ef05e5a9-1853-410a-a894-28c9ac071baf" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:to="loc_srt_CounterpartyNameAxis_ef05e5a9-1853-410a-a894-28c9ac071baf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_4e7de577-653b-4b0a-b3c1-0b77561a0542" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_ef05e5a9-1853-410a-a894-28c9ac071baf" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_4e7de577-653b-4b0a-b3c1-0b77561a0542" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SerumMember_9e372fc8-a5d0-4df8-823a-fdc88eb7d3a8" xlink:href="dyai-20191231.xsd#dyai_SerumMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_4e7de577-653b-4b0a-b3c1-0b77561a0542" xlink:to="loc_dyai_SerumMember_9e372fc8-a5d0-4df8-823a-fdc88eb7d3a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_bf5e81e5-dace-4be4-b46f-c85508ba6fd8" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_bf5e81e5-dace-4be4-b46f-c85508ba6fd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_6867c729-4fcb-4412-b942-26a073db5777" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_bf5e81e5-dace-4be4-b46f-c85508ba6fd8" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_6867c729-4fcb-4412-b942-26a073db5777" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_AlphazymeMember_10595fcd-ba80-4b32-8310-378fdd31a82e" xlink:href="dyai-20191231.xsd#dyai_AlphazymeMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_6867c729-4fcb-4412-b942-26a073db5777" xlink:to="loc_dyai_AlphazymeMember_10595fcd-ba80-4b32-8310-378fdd31a82e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_NovovetMember_bb0009ec-e656-44c7-b026-6060d091fee0" xlink:href="dyai-20191231.xsd#dyai_NovovetMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_6867c729-4fcb-4412-b942-26a073db5777" xlink:to="loc_dyai_NovovetMember_bb0009ec-e656-44c7-b026-6060d091fee0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_8c967640-4443-4a88-9227-8a96ed509f4c" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementDurationOfAgreement_70f7d229-ff56-4afe-947b-89b7a9c12989" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementDurationOfAgreement"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementDurationOfAgreement_70f7d229-ff56-4afe-947b-89b7a9c12989" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementPaymentforResearchandDevelopmentAgreement_a9f9d07e-8d99-437e-a666-70330a3c753f" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementPaymentforResearchandDevelopmentAgreement"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementPaymentforResearchandDevelopmentAgreement_a9f9d07e-8d99-437e-a666-70330a3c753f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementEquityInterestAcquired_5b69082a-18fd-4590-9988-74a88724a2db" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementEquityInterestAcquired"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementEquityInterestAcquired_5b69082a-18fd-4590-9988-74a88724a2db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementMinimumObligationForResearchAndDevelopment_f82d45b1-c702-402f-b58b-3433dd0963f1" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementMinimumObligationForResearchAndDevelopment"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementMinimumObligationForResearchAndDevelopment_f82d45b1-c702-402f-b58b-3433dd0963f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementRevenueSharingPercentage_f3339ebc-d758-46ef-80c1-b9b03e588dc1" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementRevenueSharingPercentage"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementRevenueSharingPercentage_f3339ebc-d758-46ef-80c1-b9b03e588dc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementMaximumObligationForResearchAndDevelopment_55a20d02-d5cf-4fda-9f35-711912c02028" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementMaximumObligationForResearchAndDevelopment"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementMaximumObligationForResearchAndDevelopment_55a20d02-d5cf-4fda-9f35-711912c02028" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementPaymentforAdditionalDevelopmentandCommercialization_74409a1d-c34a-4a9e-b2c4-1931bfe6d20d" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementPaymentforAdditionalDevelopmentandCommercialization"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementPaymentforAdditionalDevelopmentandCommercialization_74409a1d-c34a-4a9e-b2c4-1931bfe6d20d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementOutstandingCommitment_1e23692a-4faa-4f89-a393-4736d751a6eb" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementOutstandingCommitment"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementOutstandingCommitment_1e23692a-4faa-4f89-a393-4736d751a6eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_PrepaidResearchandDevelopment_81642a1d-c846-4f0a-9e01-a0a274bac68d" xlink:href="dyai-20191231.xsd#dyai_PrepaidResearchandDevelopment"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_PrepaidResearchandDevelopment_81642a1d-c846-4f0a-9e01-a0a274bac68d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchandDevelopmentExpenseRelatedParty_c7dc8ffb-d7cd-46a2-a26d-01185efb4f7e" xlink:href="dyai-20191231.xsd#dyai_ResearchandDevelopmentExpenseRelatedParty"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_ResearchandDevelopmentExpenseRelatedParty_c7dc8ffb-d7cd-46a2-a26d-01185efb4f7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_fc58d8ee-414e-495a-a867-ac39a716ca66" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_fc58d8ee-414e-495a-a867-ac39a716ca66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementExclusivityPeriod_2f59ed1a-03a2-4369-a8de-4b1415c23cc1" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementExclusivityPeriod"/>
<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementExclusivityPeriod_2f59ed1a-03a2-4369-a8de-4b1415c23cc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementOptionToExtendExclusivityPeriod_56dcfd72-87e6-48ff-b856-67bed4486dd3" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementOptionToExtendExclusivityPeriod"/>
<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementOptionToExtendExclusivityPeriod_56dcfd72-87e6-48ff-b856-67bed4486dd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementOwnershipInterestConsiderationReceivableUponExtensionOfExclusivityPeriod_21a432fe-beec-43ba-a8aa-a09c3583feac" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementOwnershipInterestConsiderationReceivableUponExtensionOfExclusivityPeriod"/>
<link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementOwnershipInterestConsiderationReceivableUponExtensionOfExclusivityPeriod_21a432fe-beec-43ba-a8aa-a09c3583feac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementNumberofAntibodiesandVaccinesForDevelopmentAndCommercialization_53e801b9-fd71-441e-b81c-d84f03fc3a82" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementNumberofAntibodiesandVaccinesForDevelopmentAndCommercialization"/>
<link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementNumberofAntibodiesandVaccinesForDevelopmentAndCommercialization_53e801b9-fd71-441e-b81c-d84f03fc3a82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementOptiontoObtainExclusiveCommercialSubLicenseForNumberofProteins_5524442a-525c-4547-83a1-03545442acc5" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementOptiontoObtainExclusiveCommercialSubLicenseForNumberofProteins"/>
<link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementOptiontoObtainExclusiveCommercialSubLicenseForNumberofProteins_5524442a-525c-4547-83a1-03545442acc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CollaborativeArrangementResearchFundingMilestonePaymentsAndRoyaltiesPeriod_3b9e415f-ce97-451d-8130-6abb7a478657" xlink:href="dyai-20191231.xsd#dyai_CollaborativeArrangementResearchFundingMilestonePaymentsAndRoyaltiesPeriod"/>
<link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_CollaborativeArrangementResearchFundingMilestonePaymentsAndRoyaltiesPeriod_3b9e415f-ce97-451d-8130-6abb7a478657" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_RevenueFromCollaborativeArrangementRecognized_6136dba6-7610-490f-b90c-716098de1bc1" xlink:href="dyai-20191231.xsd#dyai_RevenueFromCollaborativeArrangementRecognized"/>
<link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_7a7711dd-6930-4471-81c1-be8f4f22f3b2" xlink:to="loc_dyai_RevenueFromCollaborativeArrangementRecognized_6136dba6-7610-490f-b90c-716098de1bc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/IncomeTaxes" xlink:type="simple" xlink:href="dyai-20191231.xsd#IncomeTaxes"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/IncomeTaxes" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_069f92fc-860f-4ffb-9479-e2b956f07cdb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_cbe4d6fc-b09e-4d00-9003-3a5663ba4213" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_069f92fc-860f-4ffb-9479-e2b956f07cdb" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_cbe4d6fc-b09e-4d00-9003-3a5663ba4213" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/IncomeTaxesTables" xlink:type="simple" xlink:href="dyai-20191231.xsd#IncomeTaxesTables"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/IncomeTaxesTables" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_24afef5e-a96e-4073-a0ae-c37d6d55f580" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_2d0fb793-5393-426d-a7d4-3281e819b1d1" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_24afef5e-a96e-4073-a0ae-c37d6d55f580" xlink:to="loc_us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_2d0fb793-5393-426d-a7d4-3281e819b1d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_f8df756f-7bd6-4062-b490-af578144a078" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_24afef5e-a96e-4073-a0ae-c37d6d55f580" xlink:to="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_f8df756f-7bd6-4062-b490-af578144a078" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_42b0318f-f818-4067-ab2e-6e86bda82ec7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_24afef5e-a96e-4073-a0ae-c37d6d55f580" xlink:to="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_42b0318f-f818-4067-ab2e-6e86bda82ec7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_dca63f24-bd21-4da3-8ebd-7f5bb5f14a25" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_24afef5e-a96e-4073-a0ae-c37d6d55f580" xlink:to="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_dca63f24-bd21-4da3-8ebd-7f5bb5f14a25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/IncomeTaxesTextualDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#IncomeTaxesTextualDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/IncomeTaxesTextualDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_214c6cc8-b130-40b9-8b6f-37ac7ca51423" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwardsTable_d1c72db8-6888-4aaa-bce1-aa82f2e5523a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLossCarryforwardsTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_214c6cc8-b130-40b9-8b6f-37ac7ca51423" xlink:to="loc_us-gaap_OperatingLossCarryforwardsTable_d1c72db8-6888-4aaa-bce1-aa82f2e5523a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_d8824c67-25d6-4cc2-ae35-a147b016950e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_d1c72db8-6888-4aaa-bce1-aa82f2e5523a" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_d8824c67-25d6-4cc2-ae35-a147b016950e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_756973d8-c99b-4d6b-9fa8-eb4932839c8d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_d8824c67-25d6-4cc2-ae35-a147b016950e" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_756973d8-c99b-4d6b-9fa8-eb4932839c8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MinistryOfFinanceIndiaMember_b51d97b0-2fdf-402b-9b46-4097c62560c3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MinistryOfFinanceIndiaMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_756973d8-c99b-4d6b-9fa8-eb4932839c8d" xlink:to="loc_us-gaap_MinistryOfFinanceIndiaMember_b51d97b0-2fdf-402b-9b46-4097c62560c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwardsLineItems_9d4bbd72-3e93-41ef-bba4-e56b455bb1d6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLossCarryforwardsLineItems"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_d1c72db8-6888-4aaa-bce1-aa82f2e5523a" xlink:to="loc_us-gaap_OperatingLossCarryforwardsLineItems_9d4bbd72-3e93-41ef-bba4-e56b455bb1d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_TaxCutsandJobsActChangeInAlternativeMinimumTaxIncomeTaxBenefit_60caafd8-dcd8-4165-853c-026201c32d79" xlink:href="dyai-20191231.xsd#dyai_TaxCutsandJobsActChangeInAlternativeMinimumTaxIncomeTaxBenefit"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_9d4bbd72-3e93-41ef-bba4-e56b455bb1d6" xlink:to="loc_dyai_TaxCutsandJobsActChangeInAlternativeMinimumTaxIncomeTaxBenefit_60caafd8-dcd8-4165-853c-026201c32d79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIncomeTaxRefunds_b2d75de8-e182-4061-a108-a83b98c02618" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromIncomeTaxRefunds"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_9d4bbd72-3e93-41ef-bba4-e56b455bb1d6" xlink:to="loc_us-gaap_ProceedsFromIncomeTaxRefunds_b2d75de8-e182-4061-a108-a83b98c02618" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwards_6b566910-8ed9-4fcb-92e7-279b53ae99e8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLossCarryforwards"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_9d4bbd72-3e93-41ef-bba4-e56b455bb1d6" xlink:to="loc_us-gaap_OperatingLossCarryforwards_6b566910-8ed9-4fcb-92e7-279b53ae99e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_a451e232-c2c5-4e46-bed5-b19912aab04a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UnrecognizedTaxBenefits"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_9d4bbd72-3e93-41ef-bba4-e56b455bb1d6" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_a451e232-c2c5-4e46-bed5-b19912aab04a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignIncomeTaxExpenseBenefitContinuingOperations_57052ac7-08c8-4ead-b3b1-a15742e27c50" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignIncomeTaxExpenseBenefitContinuingOperations"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_9d4bbd72-3e93-41ef-bba4-e56b455bb1d6" xlink:to="loc_us-gaap_ForeignIncomeTaxExpenseBenefitContinuingOperations_57052ac7-08c8-4ead-b3b1-a15742e27c50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/IncomeTaxesComponentsofLossBeforeIncomeTaxesDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#IncomeTaxesComponentsofLossBeforeIncomeTaxesDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/IncomeTaxesComponentsofLossBeforeIncomeTaxesDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_fd086d30-2c13-4bb0-bdaf-7c95fe5362a8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_e4c13913-f272-4075-b9ec-4c4643ba43ad" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_fd086d30-2c13-4bb0-bdaf-7c95fe5362a8" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_e4c13913-f272-4075-b9ec-4c4643ba43ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_0a4a6ed2-ea16-426a-906f-76cec7636e17" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_fd086d30-2c13-4bb0-bdaf-7c95fe5362a8" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_0a4a6ed2-ea16-426a-906f-76cec7636e17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossAttributableToParent_26f481ba-1dd6-4ded-b8af-977559dabcfc" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossAttributableToParent"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_fd086d30-2c13-4bb0-bdaf-7c95fe5362a8" xlink:to="loc_us-gaap_IncomeLossAttributableToParent_26f481ba-1dd6-4ded-b8af-977559dabcfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/IncomeTaxesBenefitProvisionforIncomeTaxDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#IncomeTaxesBenefitProvisionforIncomeTaxDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/IncomeTaxesBenefitProvisionforIncomeTaxDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_52acd64e-60b7-4d59-a11b-7f4f932aed8c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FederalIncomeTaxExpenseBenefitContinuingOperations_1a80c481-ab26-46d2-b5b2-e476a50b6939" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FederalIncomeTaxExpenseBenefitContinuingOperations"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_52acd64e-60b7-4d59-a11b-7f4f932aed8c" xlink:to="loc_us-gaap_FederalIncomeTaxExpenseBenefitContinuingOperations_1a80c481-ab26-46d2-b5b2-e476a50b6939" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StateAndLocalIncomeTaxExpenseBenefitContinuingOperations_e3dbc857-f954-4e97-a554-c8bda7d321e2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StateAndLocalIncomeTaxExpenseBenefitContinuingOperations"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_52acd64e-60b7-4d59-a11b-7f4f932aed8c" xlink:to="loc_us-gaap_StateAndLocalIncomeTaxExpenseBenefitContinuingOperations_e3dbc857-f954-4e97-a554-c8bda7d321e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignIncomeTaxExpenseBenefitContinuingOperations_1288b17a-3460-4a0b-9b37-fe25c58a1489" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignIncomeTaxExpenseBenefitContinuingOperations"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_52acd64e-60b7-4d59-a11b-7f4f932aed8c" xlink:to="loc_us-gaap_ForeignIncomeTaxExpenseBenefitContinuingOperations_1288b17a-3460-4a0b-9b37-fe25c58a1489" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_IncomeTaxExpenseBenefitIncludingTrueUpAdjustment_421e1d82-a2b9-4179-a2f4-27f4af61f482" xlink:href="dyai-20191231.xsd#dyai_IncomeTaxExpenseBenefitIncludingTrueUpAdjustment"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_52acd64e-60b7-4d59-a11b-7f4f932aed8c" xlink:to="loc_dyai_IncomeTaxExpenseBenefitIncludingTrueUpAdjustment_421e1d82-a2b9-4179-a2f4-27f4af61f482" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/IncomeTaxesReconciliationIncomeTaxesDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#IncomeTaxesReconciliationIncomeTaxesDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/IncomeTaxesReconciliationIncomeTaxesDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_ed92df69-a3ef-45b1-942c-6c55085a185d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_ed92df69-a3ef-45b1-942c-6c55085a185d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_eeb0dc02-f84c-4111-b4a6-bea7f45a1b60" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_eeb0dc02-f84c-4111-b4a6-bea7f45a1b60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpense_fe0aa099-1436-4f2b-8590-dd4ea2659286" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpense"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpense_fe0aa099-1436-4f2b-8590-dd4ea2659286" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_0e701dbb-d9fe-476c-a31a-7b2b8cf4bb6d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_0e701dbb-d9fe-476c-a31a-7b2b8cf4bb6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_EffectiveIncomeTaxRateReconciliationTrueUpAdjustmentPercent_cb421597-bb4d-42d7-8750-acc38b1ad11f" xlink:href="dyai-20191231.xsd#dyai_EffectiveIncomeTaxRateReconciliationTrueUpAdjustmentPercent"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_dyai_EffectiveIncomeTaxRateReconciliationTrueUpAdjustmentPercent_cb421597-bb4d-42d7-8750-acc38b1ad11f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_cead4ac1-591c-4ae5-a9ec-4092542b522f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_cead4ac1-591c-4ae5-a9ec-4092542b522f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate_f8f2a7d1-d05d-40db-8243-39be06e69210" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate_f8f2a7d1-d05d-40db-8243-39be06e69210" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_EffectiveIncomeTaxRateReconciliationAlternativeMinimumTaxPercent_eafe2051-18ee-46c6-8c84-4ebe7b43916d" xlink:href="dyai-20191231.xsd#dyai_EffectiveIncomeTaxRateReconciliationAlternativeMinimumTaxPercent"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_dyai_EffectiveIncomeTaxRateReconciliationAlternativeMinimumTaxPercent_eafe2051-18ee-46c6-8c84-4ebe7b43916d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_298b6615-c7ef-4c70-ba5f-d7c6631e4ba8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_af9d8471-897b-4e2a-9688-b224cd9795fc" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_298b6615-c7ef-4c70-ba5f-d7c6631e4ba8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/IncomeTaxesDeferredIncomeTaxAssetsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#IncomeTaxesDeferredIncomeTaxAssetsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/IncomeTaxesDeferredIncomeTaxAssetsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_fc26c5e7-2d1c-430d-958f-dcf0ad10c047" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_fc26c5e7-2d1c-430d-958f-dcf0ad10c047" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_138b384f-2077-4658-a377-c6f1dd5686a2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_138b384f-2077-4658-a377-c6f1dd5686a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_2e46dccf-8182-475a-a473-c4dfcc1add59" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_2e46dccf-8182-475a-a473-c4dfcc1add59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_01afc083-87d7-4d7e-905c-c912a803a02d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOther"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_01afc083-87d7-4d7e-905c-c912a803a02d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_DeferredTaxAssetLiabilityGross_79d19a4c-5921-41de-967d-8596600728c9" xlink:href="dyai-20191231.xsd#dyai_DeferredTaxAssetLiabilityGross"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:to="loc_dyai_DeferredTaxAssetLiabilityGross_79d19a4c-5921-41de-967d-8596600728c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_c5066051-90ae-4fed-a3b2-78fe06e3be80" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_c5066051-90ae-4fed-a3b2-78fe06e3be80" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_02b8b58a-237d-4226-ba2d-4280b2bf4549" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7d05003e-109b-4ab9-bc81-e629f4a335de" xlink:to="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_02b8b58a-237d-4226-ba2d-4280b2bf4549" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="dyai-20191231.xsd#CommitmentsandContingencies"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CommitmentsandContingencies" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_97700fd7-c07f-4b99-a67f-b4b4480c0d11" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_4b4dda99-0543-4dfd-94fc-f2cc8a7900a4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_97700fd7-c07f-4b99-a67f-b4b4480c0d11" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_4b4dda99-0543-4dfd-94fc-f2cc8a7900a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CommitmentsandContingenciesTables" xlink:type="simple" xlink:href="dyai-20191231.xsd#CommitmentsandContingenciesTables"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CommitmentsandContingenciesTables" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b015651a-8d3d-4e4d-a213-75afaf808ccb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermPurchaseCommitmentTextBlock_ee7436a9-27f4-4c32-82e9-66b5d9593113" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermPurchaseCommitmentTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b015651a-8d3d-4e4d-a213-75afaf808ccb" xlink:to="loc_us-gaap_LongTermPurchaseCommitmentTextBlock_ee7436a9-27f4-4c32-82e9-66b5d9593113" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CommitmentsandContingenciesTextualDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#CommitmentsandContingenciesTextualDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CommitmentsandContingenciesTextualDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_e034780a-b619-4361-9d3c-e35c84468110" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermPurchaseCommitmentTable_6951b539-3f3f-46e1-acef-64bcbde9c475" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermPurchaseCommitmentTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_e034780a-b619-4361-9d3c-e35c84468110" xlink:to="loc_us-gaap_LongTermPurchaseCommitmentTable_6951b539-3f3f-46e1-acef-64bcbde9c475" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_LeaseTypeAxis_e4ba8bd9-97d7-414f-a118-5dc485c93817" xlink:href="dyai-20191231.xsd#dyai_LeaseTypeAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentTable_6951b539-3f3f-46e1-acef-64bcbde9c475" xlink:to="loc_dyai_LeaseTypeAxis_e4ba8bd9-97d7-414f-a118-5dc485c93817" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_LeaseTypeDomain_b6514807-2215-4860-9c5f-89f6eb801242" xlink:href="dyai-20191231.xsd#dyai_LeaseTypeDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dyai_LeaseTypeAxis_e4ba8bd9-97d7-414f-a118-5dc485c93817" xlink:to="loc_dyai_LeaseTypeDomain_b6514807-2215-4860-9c5f-89f6eb801242" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_JupiterFloridaHeadquartersLeaseMember_999734e4-d236-49a8-8d50-2e92c43fb458" xlink:href="dyai-20191231.xsd#dyai_JupiterFloridaHeadquartersLeaseMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dyai_LeaseTypeDomain_b6514807-2215-4860-9c5f-89f6eb801242" xlink:to="loc_dyai_JupiterFloridaHeadquartersLeaseMember_999734e4-d236-49a8-8d50-2e92c43fb458" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_NetherlandsOfficeLeaseMember_5540d17a-d3d9-4203-bb9e-7b993b44e633" xlink:href="dyai-20191231.xsd#dyai_NetherlandsOfficeLeaseMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dyai_LeaseTypeDomain_b6514807-2215-4860-9c5f-89f6eb801242" xlink:to="loc_dyai_NetherlandsOfficeLeaseMember_5540d17a-d3d9-4203-bb9e-7b993b44e633" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_7147bc88-5e9d-4273-b024-33edaa9ee7e0" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentTable_6951b539-3f3f-46e1-acef-64bcbde9c475" xlink:to="loc_srt_CounterpartyNameAxis_7147bc88-5e9d-4273-b024-33edaa9ee7e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_9b586c31-5980-4810-921e-d59f752d87ae" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_7147bc88-5e9d-4273-b024-33edaa9ee7e0" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_9b586c31-5980-4810-921e-d59f752d87ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_VTTTechnicalResearchCentreofFinlandLtdMember_b969d460-b546-4ff2-9b88-6ed037a846ee" xlink:href="dyai-20191231.xsd#dyai_VTTTechnicalResearchCentreofFinlandLtdMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_9b586c31-5980-4810-921e-d59f752d87ae" xlink:to="loc_dyai_VTTTechnicalResearchCentreofFinlandLtdMember_b969d460-b546-4ff2-9b88-6ed037a846ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermPurchaseCommitmentLineItems"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentTable_6951b539-3f3f-46e1-acef-64bcbde9c475" xlink:to="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AreaOfRealEstateProperty_05001f99-44a3-48ed-a7e2-8d5351640428" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AreaOfRealEstateProperty"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_us-gaap_AreaOfRealEstateProperty_05001f99-44a3-48ed-a7e2-8d5351640428" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_OperatingLeasesMonthlyRentalRate_d986900e-77a7-45b7-b3db-f98fb2c8d257" xlink:href="dyai-20191231.xsd#dyai_OperatingLeasesMonthlyRentalRate"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_OperatingLeasesMonthlyRentalRate_d986900e-77a7-45b7-b3db-f98fb2c8d257" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_OperatingLeasesAnnualRentalRate_c7455155-e654-4838-83a0-e6146213e317" xlink:href="dyai-20191231.xsd#dyai_OperatingLeasesAnnualRentalRate"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_OperatingLeasesAnnualRentalRate_c7455155-e654-4838-83a0-e6146213e317" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseTermOfContract_44c32ac8-61dd-4821-a4f0-93d85158b2dd" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseTermOfContract"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_us-gaap_LesseeOperatingLeaseTermOfContract_44c32ac8-61dd-4821-a4f0-93d85158b2dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CommitmentToPay_25ea064e-abd8-4602-b32b-a8b6ba2d26b2" xlink:href="dyai-20191231.xsd#dyai_CommitmentToPay"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_CommitmentToPay_25ea064e-abd8-4602-b32b-a8b6ba2d26b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CommitmentDevelopmentPeriod_26c3e80d-6360-4f8f-9444-a71e532d8381" xlink:href="dyai-20191231.xsd#dyai_CommitmentDevelopmentPeriod"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_CommitmentDevelopmentPeriod_26c3e80d-6360-4f8f-9444-a71e532d8381" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CommitmentSuccessBonusAward_4c317496-38d9-42e5-9dca-d19911110062" xlink:href="dyai-20191231.xsd#dyai_CommitmentSuccessBonusAward"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_CommitmentSuccessBonusAward_4c317496-38d9-42e5-9dca-d19911110062" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CommitmentToPayExpanded_2ce2041e-327e-4a11-ad3d-109d8a0c762b" xlink:href="dyai-20191231.xsd#dyai_CommitmentToPayExpanded"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_CommitmentToPayExpanded_2ce2041e-327e-4a11-ad3d-109d8a0c762b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CommitmentToPayExpandedPeriod_0d6845ab-8107-421f-85cb-4dd14f5df262" xlink:href="dyai-20191231.xsd#dyai_CommitmentToPayExpandedPeriod"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_CommitmentToPayExpandedPeriod_0d6845ab-8107-421f-85cb-4dd14f5df262" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_CommitmentsRightToTerminateContractNoticePeriod_ebecf685-e15c-4e8c-91b9-420fdb5da25b" xlink:href="dyai-20191231.xsd#dyai_CommitmentsRightToTerminateContractNoticePeriod"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermPurchaseCommitmentLineItems_0b925a6a-3443-430f-b307-d9a843d7b09c" xlink:to="loc_dyai_CommitmentsRightToTerminateContractNoticePeriod_ebecf685-e15c-4e8c-91b9-420fdb5da25b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/CommitmentsandContingenciesPurchaseObligationsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#CommitmentsandContingenciesPurchaseObligationsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/CommitmentsandContingenciesPurchaseObligationsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_062691d6-eb03-436a-bf88-1c1f9ff3dfec" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_f29319db-9764-4968-93f1-50ce8a430368" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PurchaseObligationDueInNextTwelveMonths"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_062691d6-eb03-436a-bf88-1c1f9ff3dfec" xlink:to="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_f29319db-9764-4968-93f1-50ce8a430368" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInSecondYear_3dc1eb8e-891d-4495-a8ef-52320adee9b5" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PurchaseObligationDueInSecondYear"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_062691d6-eb03-436a-bf88-1c1f9ff3dfec" xlink:to="loc_us-gaap_PurchaseObligationDueInSecondYear_3dc1eb8e-891d-4495-a8ef-52320adee9b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInThirdYear_8724d36f-8363-4a26-88c6-cec2e5c467f7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PurchaseObligationDueInThirdYear"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_062691d6-eb03-436a-bf88-1c1f9ff3dfec" xlink:to="loc_us-gaap_PurchaseObligationDueInThirdYear_8724d36f-8363-4a26-88c6-cec2e5c467f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligation_193f74cf-a0ce-40bf-9d28-b96c2edbab3f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PurchaseObligation"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_062691d6-eb03-436a-bf88-1c1f9ff3dfec" xlink:to="loc_us-gaap_PurchaseObligation_193f74cf-a0ce-40bf-9d28-b96c2edbab3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareBasedCompensation" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareBasedCompensation"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareBasedCompensation" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_0a96fd84-34d2-485b-b804-db2b1134c46a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_3d52310c-3f93-4fa4-b7b3-ca134837b1b0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_0a96fd84-34d2-485b-b804-db2b1134c46a" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_3d52310c-3f93-4fa4-b7b3-ca134837b1b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareBasedCompensationTables" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareBasedCompensationTables"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareBasedCompensationTables" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_967a26a7-7122-48a7-b5bb-12043a94a53a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_a1d0c524-8e20-4f27-95a9-fb77cc1b7630" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_967a26a7-7122-48a7-b5bb-12043a94a53a" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_a1d0c524-8e20-4f27-95a9-fb77cc1b7630" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_6d065bf8-d585-4525-9e2e-60da506550da" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_967a26a7-7122-48a7-b5bb-12043a94a53a" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_6d065bf8-d585-4525-9e2e-60da506550da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationActivityTableTextBlock_eb571752-ba55-4dbf-94f1-3d17f7846d46" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationActivityTableTextBlock"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_967a26a7-7122-48a7-b5bb-12043a94a53a" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationActivityTableTextBlock_eb571752-ba55-4dbf-94f1-3d17f7846d46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareBasedCompensationTextualDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareBasedCompensationTextualDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareBasedCompensationTextualDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3e20e420-eeec-4ad5-b206-e0b2ce2148a2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c337dcf0-fbea-4883-97c4-ceb324737006" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3e20e420-eeec-4ad5-b206-e0b2ce2148a2" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c337dcf0-fbea-4883-97c4-ceb324737006" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_fd0a21e2-07b8-4fec-8d34-6198f59d15ab" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c337dcf0-fbea-4883-97c4-ceb324737006" xlink:to="loc_us-gaap_PlanNameAxis_fd0a21e2-07b8-4fec-8d34-6198f59d15ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_c9fb94a0-0dd6-49de-a61f-61bf7e083bc5" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_fd0a21e2-07b8-4fec-8d34-6198f59d15ab" xlink:to="loc_us-gaap_PlanNameDomain_c9fb94a0-0dd6-49de-a61f-61bf7e083bc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_A2006PlanMember_75179b9e-e8a9-448f-af4e-9b17269528f2" xlink:href="dyai-20191231.xsd#dyai_A2006PlanMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_c9fb94a0-0dd6-49de-a61f-61bf7e083bc5" xlink:to="loc_dyai_A2006PlanMember_75179b9e-e8a9-448f-af4e-9b17269528f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_A2011PlanMember_bc774ffc-754e-42a2-9cd4-1c548a6a44da" xlink:href="dyai-20191231.xsd#dyai_A2011PlanMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_c9fb94a0-0dd6-49de-a61f-61bf7e083bc5" xlink:to="loc_dyai_A2011PlanMember_bc774ffc-754e-42a2-9cd4-1c548a6a44da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_a28d872a-8352-4351-9272-5170bb6fca7b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c337dcf0-fbea-4883-97c4-ceb324737006" xlink:to="loc_us-gaap_AwardTypeAxis_a28d872a-8352-4351-9272-5170bb6fca7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_dd8442f7-a8e2-48c1-bf08-221acc12653d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_a28d872a-8352-4351-9272-5170bb6fca7b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_dd8442f7-a8e2-48c1-bf08-221acc12653d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_3864c0cc-166c-46f2-be76-feead0ea5891" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_dd8442f7-a8e2-48c1-bf08-221acc12653d" xlink:to="loc_us-gaap_EmployeeStockOptionMember_3864c0cc-166c-46f2-be76-feead0ea5891" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PerformanceSharesMember_da842b01-5240-467e-8a54-924bacd97b55" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PerformanceSharesMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_dd8442f7-a8e2-48c1-bf08-221acc12653d" xlink:to="loc_us-gaap_PerformanceSharesMember_da842b01-5240-467e-8a54-924bacd97b55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TitleOfIndividualAxis_321ac3cf-b675-4d64-bc67-02ed466d81d6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TitleOfIndividualAxis"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c337dcf0-fbea-4883-97c4-ceb324737006" xlink:to="loc_us-gaap_TitleOfIndividualAxis_321ac3cf-b675-4d64-bc67-02ed466d81d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_dde69e58-307d-4eaa-8047-888e09f71b73" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TitleOfIndividualWithRelationshipToEntityDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualAxis_321ac3cf-b675-4d64-bc67-02ed466d81d6" xlink:to="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_dde69e58-307d-4eaa-8047-888e09f71b73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChiefExecutiveOfficerMember_24dd52cb-7b92-4d93-b2e2-3b21b8a101b0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ChiefExecutiveOfficerMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_dde69e58-307d-4eaa-8047-888e09f71b73" xlink:to="loc_us-gaap_ChiefExecutiveOfficerMember_24dd52cb-7b92-4d93-b2e2-3b21b8a101b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ContractorMember_259a5e86-5fce-42a5-a31a-1489cf4f47b6" xlink:href="dyai-20191231.xsd#dyai_ContractorMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_dde69e58-307d-4eaa-8047-888e09f71b73" xlink:to="loc_dyai_ContractorMember_259a5e86-5fce-42a5-a31a-1489cf4f47b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c337dcf0-fbea-4883-97c4-ceb324737006" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_f139260c-04c0-4ace-93c8-50c04721eb4b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_f139260c-04c0-4ace-93c8-50c04721eb4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_59573b2e-1f7d-499f-a1d1-936f1d879d85" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_59573b2e-1f7d-499f-a1d1-936f1d879d85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_e220f707-b5f0-4399-b9e0-d1f02fa9572f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_e220f707-b5f0-4399-b9e0-d1f02fa9572f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_e6f059ca-9aad-4072-a280-37c77585d1fb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_e6f059ca-9aad-4072-a280-37c77585d1fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_0ef38ec3-9ac6-4165-b056-d7cbdebdcb44" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_0ef38ec3-9ac6-4165-b056-d7cbdebdcb44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_ce4855d0-c566-4940-92a0-cffd70ac660d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_ce4855d0-c566-4940-92a0-cffd70ac660d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_de96c289-2edd-4717-928d-9ad17eb79084" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_de96c289-2edd-4717-928d-9ad17eb79084" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_9bdb2683-072a-4c9c-9ce6-24951225b294" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_9bdb2683-072a-4c9c-9ce6-24951225b294" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_61e9c051-9100-46c2-a5aa-f8c49c236b7d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_61e9c051-9100-46c2-a5aa-f8c49c236b7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_3751a1c2-a4f1-41c7-8ea1-a541afc9543c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_3751a1c2-a4f1-41c7-8ea1-a541afc9543c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_0f5731ee-c6a2-491c-be55-cc166745d873" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_0f5731ee-c6a2-491c-be55-cc166745d873" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_4ecd9ea4-68d1-4b2b-af45-c3a601ca8365" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensation"/>
<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fe9a38cf-e03d-4278-b0c5-322972a80be6" xlink:to="loc_us-gaap_ShareBasedCompensation_4ecd9ea4-68d1-4b2b-af45-c3a601ca8365" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareBasedCompensationAssumptionsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareBasedCompensationAssumptionsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareBasedCompensationAssumptionsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c79c8582-563f-43ce-beef-4de4bfc5e15c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_940a0268-5f20-477d-8c19-11ff087ad4ba" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c79c8582-563f-43ce-beef-4de4bfc5e15c" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_940a0268-5f20-477d-8c19-11ff087ad4ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_2e753dc9-ea05-4f96-b2de-2ffbcac75f7b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_940a0268-5f20-477d-8c19-11ff087ad4ba" xlink:to="loc_us-gaap_AwardTypeAxis_2e753dc9-ea05-4f96-b2de-2ffbcac75f7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_d27cd22d-4848-4d4a-802b-1edaab5d65d8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_2e753dc9-ea05-4f96-b2de-2ffbcac75f7b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_d27cd22d-4848-4d4a-802b-1edaab5d65d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_913476db-5c69-4f02-8a80-e7ed925cbbc2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_d27cd22d-4848-4d4a-802b-1edaab5d65d8" xlink:to="loc_us-gaap_EmployeeStockOptionMember_913476db-5c69-4f02-8a80-e7ed925cbbc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_48b0bdee-4236-4efa-89b5-a6726c1c13a4" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_940a0268-5f20-477d-8c19-11ff087ad4ba" xlink:to="loc_srt_RangeAxis_48b0bdee-4236-4efa-89b5-a6726c1c13a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_2a0d70b6-e4f1-4532-b839-c70f7e546770" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_48b0bdee-4236-4efa-89b5-a6726c1c13a4" xlink:to="loc_srt_RangeMember_2a0d70b6-e4f1-4532-b839-c70f7e546770" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_64d8d757-cd29-4022-8eda-a6680e99ed33" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MinimumMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_2a0d70b6-e4f1-4532-b839-c70f7e546770" xlink:to="loc_srt_MinimumMember_64d8d757-cd29-4022-8eda-a6680e99ed33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_16c55f2b-bd30-4782-88a2-99cce4b0af9b" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MaximumMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_2a0d70b6-e4f1-4532-b839-c70f7e546770" xlink:to="loc_srt_MaximumMember_16c55f2b-bd30-4782-88a2-99cce4b0af9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_940a0268-5f20-477d-8c19-11ff087ad4ba" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_7b9ce2bf-eb3b-4f14-b130-cc321105db59" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_7b9ce2bf-eb3b-4f14-b130-cc321105db59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_3b9bb22f-07ef-4230-87da-43458864a2c8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_3b9bb22f-07ef-4230-87da-43458864a2c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_bf653a7e-aead-468b-89ba-ec52150ec506" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_bf653a7e-aead-468b-89ba-ec52150ec506" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_9c20a922-5ed5-48b7-9e5d-de685dca1d99" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_9c20a922-5ed5-48b7-9e5d-de685dca1d99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_8b8e730d-cb70-4fae-b897-e2a67af07e7e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_8b8e730d-cb70-4fae-b897-e2a67af07e7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_3ce69fa3-4977-4b6d-bdd9-f3a3d787ab72" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_3ce69fa3-4977-4b6d-bdd9-f3a3d787ab72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardFairValueAssumptionsDiscountforLackofMarketability_5514217c-166f-450f-964d-7eb4e9963df1" xlink:href="dyai-20191231.xsd#dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardFairValueAssumptionsDiscountforLackofMarketability"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d677267d-709e-4f12-8460-12def0b4b34d" xlink:to="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardFairValueAssumptionsDiscountforLackofMarketability_5514217c-166f-450f-964d-7eb4e9963df1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareBasedCompensationStockOptionActivityDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareBasedCompensationStockOptionActivityDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareBasedCompensationStockOptionActivityDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e599953f-8fb0-4dd3-a215-dda2ac5c8f09" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e599953f-8fb0-4dd3-a215-dda2ac5c8f09" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_c068fc16-5739-464b-b778-784f9a396305" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_c068fc16-5739-464b-b778-784f9a396305" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_78ff85b4-1a17-4762-a4ad-d92b8ee5e774" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_78ff85b4-1a17-4762-a4ad-d92b8ee5e774" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_8c9644eb-6bad-4619-b5c0-0dcc0a9f0771" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_8c9644eb-6bad-4619-b5c0-0dcc0a9f0771" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_c5df0edd-7c98-487e-af95-d65eb0b18b25" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_c5df0edd-7c98-487e-af95-d65eb0b18b25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_7d227193-974b-4112-8252-42bc4868edce" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_7d227193-974b-4112-8252-42bc4868edce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_6a561806-7637-497a-a8e4-e80d16749156" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_f95575f4-eb58-4c47-ac05-cd6361243a55" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_6a561806-7637-497a-a8e4-e80d16749156" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e599953f-8fb0-4dd3-a215-dda2ac5c8f09" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_d1963055-13ce-4641-a579-3fb69b15fb01" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_d1963055-13ce-4641-a579-3fb69b15fb01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_61270ca4-b63c-4a3d-ad71-e5569913bae8" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_61270ca4-b63c-4a3d-ad71-e5569913bae8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_513d23bf-81fe-4e24-86f3-53b4cb67e777" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_513d23bf-81fe-4e24-86f3-53b4cb67e777" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_666f6aec-b518-4a18-94be-1383ba4a41e9" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_666f6aec-b518-4a18-94be-1383ba4a41e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_35172f4f-9b75-493c-92c1-2fe1a32a3c86" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_35172f4f-9b75-493c-92c1-2fe1a32a3c86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_8dec71c6-5d54-46ca-957c-95d12b21bf81" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_f934c376-c1d6-414c-b967-c82182c48078" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_8dec71c6-5d54-46ca-957c-95d12b21bf81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e599953f-8fb0-4dd3-a215-dda2ac5c8f09" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_29530ff1-02bf-4352-8e72-5c97d65b9ae3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_29530ff1-02bf-4352-8e72-5c97d65b9ae3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_d51702bd-07ea-4749-932b-70b28cc44179" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_d51702bd-07ea-4749-932b-70b28cc44179" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_230ba901-61c6-47f8-85ed-a1c4690dfe9c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_230ba901-61c6-47f8-85ed-a1c4690dfe9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_e1296618-94f9-4d8c-94e8-8b717d8978a6" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_e1296618-94f9-4d8c-94e8-8b717d8978a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_ca9b814d-1907-45c5-879e-69365b7f0ad0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_ca9b814d-1907-45c5-879e-69365b7f0ad0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_5bba6c8a-ee30-4b71-9ade-eebd5762dbe4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_b4040551-8a12-4f57-81cd-4bc98816384e" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_5bba6c8a-ee30-4b71-9ade-eebd5762dbe4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareBasedCompensationStockOptionActivityTextualDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareBasedCompensationStockOptionActivityTextualDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareBasedCompensationStockOptionActivityTextualDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_9bb23fd7-b78e-4a73-aac2-49f04e8d693c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2ed7be49-fc87-42ef-8006-e448687a4002" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_9bb23fd7-b78e-4a73-aac2-49f04e8d693c" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2ed7be49-fc87-42ef-8006-e448687a4002" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_a8496130-30be-4165-aea5-0942f0147d42" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2ed7be49-fc87-42ef-8006-e448687a4002" xlink:to="loc_us-gaap_AwardTypeAxis_a8496130-30be-4165-aea5-0942f0147d42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8d5abd17-b793-4331-890d-6df605d41695" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_a8496130-30be-4165-aea5-0942f0147d42" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8d5abd17-b793-4331-890d-6df605d41695" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_b1c76c37-e6ad-40bc-8bc9-fb7dcb9be2e7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8d5abd17-b793-4331-890d-6df605d41695" xlink:to="loc_us-gaap_EmployeeStockOptionMember_b1c76c37-e6ad-40bc-8bc9-fb7dcb9be2e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TitleOfIndividualAxis_cbcc7d36-1c1e-4b5c-85c3-6bf3fd2e1112" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TitleOfIndividualAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2ed7be49-fc87-42ef-8006-e448687a4002" xlink:to="loc_us-gaap_TitleOfIndividualAxis_cbcc7d36-1c1e-4b5c-85c3-6bf3fd2e1112" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_a1871f4d-dcd0-4a72-908f-f01548489647" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TitleOfIndividualWithRelationshipToEntityDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualAxis_cbcc7d36-1c1e-4b5c-85c3-6bf3fd2e1112" xlink:to="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_a1871f4d-dcd0-4a72-908f-f01548489647" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ExecutivesandKeyPersonnelMember_90eb6df1-3be1-414a-98a4-bb767d1bcaaf" xlink:href="dyai-20191231.xsd#dyai_ExecutivesandKeyPersonnelMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_a1871f4d-dcd0-4a72-908f-f01548489647" xlink:to="loc_dyai_ExecutivesandKeyPersonnelMember_90eb6df1-3be1-414a-98a4-bb767d1bcaaf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DirectorMember_2cff933b-4c06-445f-ab57-8042e12d5cee" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DirectorMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_a1871f4d-dcd0-4a72-908f-f01548489647" xlink:to="loc_us-gaap_DirectorMember_2cff933b-4c06-445f-ab57-8042e12d5cee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_EmployeeMember_e0b9dd26-50a6-4f27-9762-5e93edeff722" xlink:href="dyai-20191231.xsd#dyai_EmployeeMember"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_a1871f4d-dcd0-4a72-908f-f01548489647" xlink:to="loc_dyai_EmployeeMember_e0b9dd26-50a6-4f27-9762-5e93edeff722" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ContractorMember_570ef466-39b4-453f-8e11-32bff02c5b76" xlink:href="dyai-20191231.xsd#dyai_ContractorMember"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_a1871f4d-dcd0-4a72-908f-f01548489647" xlink:to="loc_dyai_ContractorMember_570ef466-39b4-453f-8e11-32bff02c5b76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ChiefFinancialOfficerMember_deb637f6-87a9-476d-a6a0-26724320ef24" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ChiefFinancialOfficerMember"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_a1871f4d-dcd0-4a72-908f-f01548489647" xlink:to="loc_us-gaap_ChiefFinancialOfficerMember_deb637f6-87a9-476d-a6a0-26724320ef24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingAxis_1622af6d-0e68-4c16-9e58-313e6d1fc6df" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VestingAxis"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2ed7be49-fc87-42ef-8006-e448687a4002" xlink:to="loc_us-gaap_VestingAxis_1622af6d-0e68-4c16-9e58-313e6d1fc6df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingDomain_db552ce2-fc05-4d9f-93f7-10dd9f8bcec3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VestingDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingAxis_1622af6d-0e68-4c16-9e58-313e6d1fc6df" xlink:to="loc_us-gaap_VestingDomain_db552ce2-fc05-4d9f-93f7-10dd9f8bcec3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_3392431b-cc4d-4d79-8518-504dabe680fe" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheOneMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_db552ce2-fc05-4d9f-93f7-10dd9f8bcec3" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_3392431b-cc4d-4d79-8518-504dabe680fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SharebasedCompensationAwardTrancheTwothroughFiveMember_e053c40d-1215-457d-8ca8-8dacf1d549c7" xlink:href="dyai-20191231.xsd#dyai_SharebasedCompensationAwardTrancheTwothroughFiveMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_db552ce2-fc05-4d9f-93f7-10dd9f8bcec3" xlink:to="loc_dyai_SharebasedCompensationAwardTrancheTwothroughFiveMember_e053c40d-1215-457d-8ca8-8dacf1d549c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2ed7be49-fc87-42ef-8006-e448687a4002" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_7febfa08-1592-488d-9209-883954d41c92" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_7febfa08-1592-488d-9209-883954d41c92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_0295ac7e-3e6c-4f96-b51b-48a07a75d0aa" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_0295ac7e-3e6c-4f96-b51b-48a07a75d0aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1_9b4c9e61-6b60-4f5d-96e4-e54705da61d4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1_9b4c9e61-6b60-4f5d-96e4-e54705da61d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_8ed3222b-c598-48c2-b5ee-2b83d2e1cd08" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_8ed3222b-c598-48c2-b5ee-2b83d2e1cd08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_ff9c4306-2afd-4de7-9e88-a0337ded1600" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_ff9c4306-2afd-4de7-9e88-a0337ded1600" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_21a4816d-584d-42a5-9e92-8975b3504bf0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_21a4816d-584d-42a5-9e92-8975b3504bf0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofBoardofDirectors_8a643f1e-46e1-40d4-b8a2-4c9aab62ef0f" xlink:href="dyai-20191231.xsd#dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofBoardofDirectors"/>
<link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardNumberofBoardofDirectors_8a643f1e-46e1-40d4-b8a2-4c9aab62ef0f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_155ab4cf-bd08-489f-a4b4-ec7539415388" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
<link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_155ab4cf-bd08-489f-a4b4-ec7539415388" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_74de16ff-9d29-4025-acb5-5662c85fc19c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_74de16ff-9d29-4025-acb5-5662c85fc19c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodNet_fe1e052a-3d80-4862-a0e8-78d68b4372e9" xlink:href="dyai-20191231.xsd#dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodNet"/>
<link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodNet_fe1e052a-3d80-4862-a0e8-78d68b4372e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodCommonStock_6a68f680-cedb-4a25-ad43-735dae12df10" xlink:href="dyai-20191231.xsd#dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodCommonStock"/>
<link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodCommonStock_6a68f680-cedb-4a25-ad43-735dae12df10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodForfeited_692bf096-e914-44c9-9fab-562eec1c49d6" xlink:href="dyai-20191231.xsd#dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodForfeited"/>
<link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodForfeited_692bf096-e914-44c9-9fab-562eec1c49d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodCash_9aedbd56-3de7-441f-8fc1-bcef4633c89a" xlink:href="dyai-20191231.xsd#dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodCash"/>
<link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_48ea129e-a03f-4003-a25c-e57c17bbe277" xlink:to="loc_dyai_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodCash_9aedbd56-3de7-441f-8fc1-bcef4633c89a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareBasedCompensationCompensationExpenseDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareBasedCompensationCompensationExpenseDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareBasedCompensationCompensationExpenseDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c1d99d6d-43cf-42ce-bda3-3778d3c05f7c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ec2ad5d-51cb-41ee-94c4-9ff5de93a531" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c1d99d6d-43cf-42ce-bda3-3778d3c05f7c" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ec2ad5d-51cb-41ee-94c4-9ff5de93a531" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_7e3fca1a-c0af-4fef-8376-b0c332909c6f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ec2ad5d-51cb-41ee-94c4-9ff5de93a531" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_7e3fca1a-c0af-4fef-8376-b0c332909c6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_fd527dca-f520-4ccd-bd82-17289be7f8ae" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_7e3fca1a-c0af-4fef-8376-b0c332909c6f" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_fd527dca-f520-4ccd-bd82-17289be7f8ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_86b085ac-7a10-4ad7-8e2b-25392baac211" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GeneralAndAdministrativeExpenseMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_fd527dca-f520-4ccd-bd82-17289be7f8ae" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_86b085ac-7a10-4ad7-8e2b-25392baac211" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_14f88ecd-ed75-4ead-92ca-802b8d6bc23b" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_fd527dca-f520-4ccd-bd82-17289be7f8ae" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_14f88ecd-ed75-4ead-92ca-802b8d6bc23b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1e782f63-a679-4f30-a348-8a2f75683360" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ec2ad5d-51cb-41ee-94c4-9ff5de93a531" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1e782f63-a679-4f30-a348-8a2f75683360" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_49c3770b-e34a-465a-a0e3-1eb84c6ddece" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1e782f63-a679-4f30-a348-8a2f75683360" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_49c3770b-e34a-465a-a0e3-1eb84c6ddece" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareholdersEquity" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareholdersEquity"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareholdersEquity" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_2b966474-72ae-4956-8c80-6ec04b7702a3" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_0937a104-c427-41f9-a3e3-6c8b345cfb03" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_2b966474-72ae-4956-8c80-6ec04b7702a3" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_0937a104-c427-41f9-a3e3-6c8b345cfb03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareholdersEquityTables" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareholdersEquityTables"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareholdersEquityTables" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_15eb3bf3-b94e-4e0b-bd9e-677be883dd71" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfTreasuryStockByClassTextBlock_b76425de-90dd-4ef0-b261-bbf8f53bef12" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfTreasuryStockByClassTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_15eb3bf3-b94e-4e0b-bd9e-677be883dd71" xlink:to="loc_us-gaap_ScheduleOfTreasuryStockByClassTextBlock_b76425de-90dd-4ef0-b261-bbf8f53bef12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareholdersEquityTextualDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareholdersEquityTextualDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareholdersEquityTextualDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_f0c26d66-64d6-4aff-87d0-d48d353a9355" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod_dd53dcda-ec65-4a19-a0bc-131e7fa5d80f" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f0c26d66-64d6-4aff-87d0-d48d353a9355" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod_dd53dcda-ec65-4a19-a0bc-131e7fa5d80f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsIssuedInPeriodWeightedAverageExercisePrice_8189e730-b959-401f-8b2a-97a20fa89d46" xlink:href="dyai-20191231.xsd#dyai_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsIssuedInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f0c26d66-64d6-4aff-87d0-d48d353a9355" xlink:to="loc_dyai_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsIssuedInPeriodWeightedAverageExercisePrice_8189e730-b959-401f-8b2a-97a20fa89d46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramPeriodInForce1_48a05f07-56fe-4fa8-9b75-86c052cbd42a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockRepurchaseProgramPeriodInForce1"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f0c26d66-64d6-4aff-87d0-d48d353a9355" xlink:to="loc_us-gaap_StockRepurchaseProgramPeriodInForce1_48a05f07-56fe-4fa8-9b75-86c052cbd42a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_35016de6-5e8c-4658-b61a-3067bd15de0e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockRepurchaseProgramAuthorizedAmount1"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f0c26d66-64d6-4aff-87d0-d48d353a9355" xlink:to="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_35016de6-5e8c-4658-b61a-3067bd15de0e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonShares_133539b0-9987-4f37-9f78-f3965b800cf4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockCommonShares"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f0c26d66-64d6-4aff-87d0-d48d353a9355" xlink:to="loc_us-gaap_TreasuryStockCommonShares_133539b0-9987-4f37-9f78-f3965b800cf4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValue_6464b937-f542-4002-83c1-fcbb70b194b4" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockValue"/>
<link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f0c26d66-64d6-4aff-87d0-d48d353a9355" xlink:to="loc_us-gaap_TreasuryStockValue_6464b937-f542-4002-83c1-fcbb70b194b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/ShareholdersEquityStockRepurchaseDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#ShareholdersEquityStockRepurchaseDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/ShareholdersEquityStockRepurchaseDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_0229741a-4c5f-424a-a757-f74327e93547" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfTreasuryStockTable_3fcd72f7-dad8-46b2-a715-b82459f3fa60" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ClassOfTreasuryStockTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0229741a-4c5f-424a-a757-f74327e93547" xlink:to="loc_us-gaap_ClassOfTreasuryStockTable_3fcd72f7-dad8-46b2-a715-b82459f3fa60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareRepurchaseProgramAxis_afe5c2f1-9055-4c88-893a-bcf3295817fb" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareRepurchaseProgramAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfTreasuryStockTable_3fcd72f7-dad8-46b2-a715-b82459f3fa60" xlink:to="loc_us-gaap_ShareRepurchaseProgramAxis_afe5c2f1-9055-4c88-893a-bcf3295817fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareRepurchaseProgramDomain_f6660928-ee96-49e9-a647-e318da6e7fe2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareRepurchaseProgramDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramAxis_afe5c2f1-9055-4c88-893a-bcf3295817fb" xlink:to="loc_us-gaap_ShareRepurchaseProgramDomain_f6660928-ee96-49e9-a647-e318da6e7fe2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_PubliclyAnnouncedRepurchasePlansMember_48ef0041-e2a3-420a-bb70-5bbd2f0b7c21" xlink:href="dyai-20191231.xsd#dyai_PubliclyAnnouncedRepurchasePlansMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramDomain_f6660928-ee96-49e9-a647-e318da6e7fe2" xlink:to="loc_dyai_PubliclyAnnouncedRepurchasePlansMember_48ef0041-e2a3-420a-bb70-5bbd2f0b7c21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityClassOfTreasuryStockLineItems_cc05a4cc-dfee-4e8e-a0de-5426276267c0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityClassOfTreasuryStockLineItems"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfTreasuryStockTable_3fcd72f7-dad8-46b2-a715-b82459f3fa60" xlink:to="loc_us-gaap_EquityClassOfTreasuryStockLineItems_cc05a4cc-dfee-4e8e-a0de-5426276267c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_03d77b58-e61e-4797-b202-54ab7cfcccf0" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockSharesAcquired"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityClassOfTreasuryStockLineItems_cc05a4cc-dfee-4e8e-a0de-5426276267c0" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_03d77b58-e61e-4797-b202-54ab7cfcccf0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare_a7b5cd5f-f9f5-492c-ac23-439fbba79a8e" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockAcquiredAverageCostPerShare"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityClassOfTreasuryStockLineItems_cc05a4cc-dfee-4e8e-a0de-5426276267c0" xlink:to="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare_a7b5cd5f-f9f5-492c-ac23-439fbba79a8e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_c1566242-17e9-4f88-9778-432758cf5385" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityClassOfTreasuryStockLineItems_cc05a4cc-dfee-4e8e-a0de-5426276267c0" xlink:to="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_c1566242-17e9-4f88-9778-432758cf5385" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_c5f4270b-9de5-4544-8eae-df7af5fa15b7" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityClassOfTreasuryStockLineItems_cc05a4cc-dfee-4e8e-a0de-5426276267c0" xlink:to="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_c5f4270b-9de5-4544-8eae-df7af5fa15b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/SubsequentEvents" xlink:type="simple" xlink:href="dyai-20191231.xsd#SubsequentEvents"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/SubsequentEvents" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_b89f3fe8-25c6-40ff-b83c-63c5a97e24b9" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_5d41164f-ece0-493f-ab9d-3604b3e1b4c2" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventsTextBlock"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_b89f3fe8-25c6-40ff-b83c-63c5a97e24b9" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_5d41164f-ece0-493f-ab9d-3604b3e1b4c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
<link:roleRef roleURI="http://www.dyadic.com/role/SubsequentEventsDetails" xlink:type="simple" xlink:href="dyai-20191231.xsd#SubsequentEventsDetails"/>
<link:presentationLink xlink:role="http://www.dyadic.com/role/SubsequentEventsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_b322569b-08fb-4a40-891a-cda6cb45a209" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_dc1e0e27-ba9e-45e3-9fc8-cb336a4271de" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventTable"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_b322569b-08fb-4a40-891a-cda6cb45a209" xlink:to="loc_us-gaap_SubsequentEventTable_dc1e0e27-ba9e-45e3-9fc8-cb336a4271de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_b1f2eeba-e161-4f9a-a106-161d91497e7d" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeAxis"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_dc1e0e27-ba9e-45e3-9fc8-cb336a4271de" xlink:to="loc_srt_RangeAxis_b1f2eeba-e161-4f9a-a106-161d91497e7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_527e67c3-7c29-439a-8c8e-08fd5b65f4a8" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_b1f2eeba-e161-4f9a-a106-161d91497e7d" xlink:to="loc_srt_RangeMember_527e67c3-7c29-439a-8c8e-08fd5b65f4a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_f3f5a85b-3e5d-4497-b9eb-218d98fe4b65" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MinimumMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_527e67c3-7c29-439a-8c8e-08fd5b65f4a8" xlink:to="loc_srt_MinimumMember_f3f5a85b-3e5d-4497-b9eb-218d98fe4b65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_596dafbf-563c-4c37-87cb-9c529035795b" xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MaximumMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_527e67c3-7c29-439a-8c8e-08fd5b65f4a8" xlink:to="loc_srt_MaximumMember_596dafbf-563c-4c37-87cb-9c529035795b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TitleOfIndividualAxis_763657d9-c18f-466f-b95b-a4cc69604e53" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TitleOfIndividualAxis"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_dc1e0e27-ba9e-45e3-9fc8-cb336a4271de" xlink:to="loc_us-gaap_TitleOfIndividualAxis_763657d9-c18f-466f-b95b-a4cc69604e53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_e8654e34-c866-4e80-b77d-5435a2a007df" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TitleOfIndividualWithRelationshipToEntityDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualAxis_763657d9-c18f-466f-b95b-a4cc69604e53" xlink:to="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_e8654e34-c866-4e80-b77d-5435a2a007df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ExecutivesandKeyPersonnelMember_e0fcf89e-9428-4b90-b526-576fd22e51fc" xlink:href="dyai-20191231.xsd#dyai_ExecutivesandKeyPersonnelMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_e8654e34-c866-4e80-b77d-5435a2a007df" xlink:to="loc_dyai_ExecutivesandKeyPersonnelMember_e0fcf89e-9428-4b90-b526-576fd22e51fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DirectorMember_375842a5-da54-4e7c-842e-b4670b10c556" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DirectorMember"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_e8654e34-c866-4e80-b77d-5435a2a007df" xlink:to="loc_us-gaap_DirectorMember_375842a5-da54-4e7c-842e-b4670b10c556" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_NonexecutiveEmployeesMember_0566ac3e-a006-44a4-ae0e-8979819f718d" xlink:href="dyai-20191231.xsd#dyai_NonexecutiveEmployeesMember"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_e8654e34-c866-4e80-b77d-5435a2a007df" xlink:to="loc_dyai_NonexecutiveEmployeesMember_0566ac3e-a006-44a4-ae0e-8979819f718d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ConsultantMember_a7fbbc48-ea6e-4d79-8eec-a156f085f66a" xlink:href="dyai-20191231.xsd#dyai_ConsultantMember"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_e8654e34-c866-4e80-b77d-5435a2a007df" xlink:to="loc_dyai_ConsultantMember_a7fbbc48-ea6e-4d79-8eec-a156f085f66a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_31ed284b-2894-45bb-a9e5-88fa75009f63" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_dc1e0e27-ba9e-45e3-9fc8-cb336a4271de" xlink:to="loc_us-gaap_AwardTypeAxis_31ed284b-2894-45bb-a9e5-88fa75009f63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8af3521f-6e13-4d61-8bcd-7c7cd86ac31d" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_31ed284b-2894-45bb-a9e5-88fa75009f63" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8af3521f-6e13-4d61-8bcd-7c7cd86ac31d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_49abb604-f2bc-48f1-8bbe-c2163ad34113" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8af3521f-6e13-4d61-8bcd-7c7cd86ac31d" xlink:to="loc_us-gaap_EmployeeStockOptionMember_49abb604-f2bc-48f1-8bbe-c2163ad34113" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_4d8890bf-859c-47c7-bc52-61123801f33a" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_dc1e0e27-ba9e-45e3-9fc8-cb336a4271de" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_4d8890bf-859c-47c7-bc52-61123801f33a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_b92f2222-22c9-4d2f-ad5e-f26ad4c366ec" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_4d8890bf-859c-47c7-bc52-61123801f33a" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_b92f2222-22c9-4d2f-ad5e-f26ad4c366ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_bc720fb0-a4ee-4ea4-8a52-12d92cbb03ac" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventMember"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_b92f2222-22c9-4d2f-ad5e-f26ad4c366ec" xlink:to="loc_us-gaap_SubsequentEventMember_bc720fb0-a4ee-4ea4-8a52-12d92cbb03ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_796c7855-42a2-455c-a19b-4e9f99f27d3c" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventLineItems"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_dc1e0e27-ba9e-45e3-9fc8-cb336a4271de" xlink:to="loc_us-gaap_SubsequentEventLineItems_796c7855-42a2-455c-a19b-4e9f99f27d3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_5f8cd468-baeb-4a7c-909b-78fd01c18260" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
<link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_796c7855-42a2-455c-a19b-4e9f99f27d3c" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_5f8cd468-baeb-4a7c-909b-78fd01c18260" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_8bda47fa-60fd-4da1-8652-4689c315f5cd" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
<link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_796c7855-42a2-455c-a19b-4e9f99f27d3c" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_8bda47fa-60fd-4da1-8652-4689c315f5cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_12a02bb2-c5a4-4561-9af9-96c01edb3cde" xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
<link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_796c7855-42a2-455c-a19b-4e9f99f27d3c" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_12a02bb2-c5a4-4561-9af9-96c01edb3cde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentExpenseAdditional_9b9dcc22-11b3-42b4-9a3d-344fd7c797fa" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentExpenseAdditional"/>
<link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_796c7855-42a2-455c-a19b-4e9f99f27d3c" xlink:to="loc_dyai_ResearchAndDevelopmentExpenseAdditional_9b9dcc22-11b3-42b4-9a3d-344fd7c797fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<link:loc xlink:type="locator" xlink:label="loc_dyai_ResearchAndDevelopmentExpenseAdditionalTerm_6cdee52a-e826-417c-b8a1-9ea9e194082e" xlink:href="dyai-20191231.xsd#dyai_ResearchAndDevelopmentExpenseAdditionalTerm"/>
<link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_796c7855-42a2-455c-a19b-4e9f99f27d3c" xlink:to="loc_dyai_ResearchAndDevelopmentExpenseAdditionalTerm_6cdee52a-e826-417c-b8a1-9ea9e194082e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</link:presentationLink>
</link:linkbase>

1 Subsequent Filing that References this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/28/24  Dyadic International Inc.         10-K       12/31/23   64:6.6M                                   RDG Filings/FA
↑Top
Filing Submission 0001213809-20-000018   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)
Copyright © 2024 Fran Finnegan & Company LLC – All Rights Reserved.
About — Privacy — Redactions — Help — Sun., May 5, 1:14:09.1am ET