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Syneos Health, Inc. – ‘10-K’ for 12/31/22 – ‘EX-101.DEF’

On:  Wednesday, 2/15/23, at 5:36pm ET   ·   As of:  2/16/23   ·   For:  12/31/22   ·   Accession #:  950170-23-2928   ·   File #:  1-36730

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  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 2/16/23  Syneos Health, Inc.               10-K       12/31/22  136:28M                                    Donnelley … Solutions/FA

Annual Report   —   Form 10-K

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   6.13M 
 2: EX-4        Ex-4.9                                              HTML     53K 
 4: EX-10       Ex-10.11.12                                         HTML    292K 
 5: EX-10       Ex-10.11.13                                         HTML    377K 
 6: EX-10       Ex-10.11.14                                         HTML    359K 
 7: EX-10       Ex-10.11.15                                         HTML    275K 
 8: EX-10       Ex-10.11.16                                         HTML    392K 
 9: EX-10       Ex-10.11.17                                         HTML    433K 
 3: EX-10       Ex-10.7                                             HTML    275K 
10: EX-21       Ex-21.1                                             HTML    268K 
11: EX-23       Ex-23.1                                             HTML     35K 
12: EX-31       Ex-31.1                                             HTML     39K 
13: EX-31       Ex-31.2                                             HTML     39K 
14: EX-32       Ex-32.1                                             HTML     38K 
15: EX-32       Ex-32.2                                             HTML     38K 
21: R1          Cover Page                                          HTML    105K 
22: R2          Consolidated Statements of Income                   HTML    116K 
23: R3          Consolidated Statements of Comprehensive Income     HTML     57K 
24: R4          Consolidated Statements of Comprehensive Income     HTML     41K 
                (Parenthetical)                                                  
25: R5          Consolidated Balance Sheets                         HTML    143K 
26: R6          Consolidated Balance Sheets (Parenthetical)         HTML     53K 
27: R7          Consolidated Statements of Cash Flows               HTML    141K 
28: R8          Consolidated Statements of Shareholders' Equity     HTML     86K 
29: R9          Basis of Presentation and Summary of Significant    HTML    171K 
                Accounting Policies                                              
30: R10         Financial Statement Details                         HTML    567K 
31: R11         Acquisitions, Divestitures, and Investments         HTML    146K 
32: R12         Long-Term Debt Obligations                          HTML    175K 
33: R13         Leases                                              HTML    243K 
34: R14         Derivatives                                         HTML     79K 
35: R15         Fair Value Measurements                             HTML    284K 
36: R16         Restructuring and Other Costs                       HTML     92K 
37: R17         Shareholders' Equity                                HTML    211K 
38: R18         Earnings Per Share                                  HTML     98K 
39: R19         Income Taxes                                        HTML    436K 
40: R20         Revenue from Contracts with Customers               HTML     47K 
41: R21         Segment Information                                 HTML    170K 
42: R22         Operations by Geographic Location                   HTML    109K 
43: R23         Concentration of Credit Risk                        HTML     42K 
44: R24         Related-Party Transactions                          HTML     50K 
45: R25         Commitments and Contingencies                       HTML     49K 
46: R26         Share-Based Compensation                            HTML    238K 
47: R27         Employee Benefit Plans                              HTML     62K 
48: R28         Basis of Presentation and Summary of Significant    HTML    232K 
                Accounting Policies (Policies)                                   
49: R29         Basis of Presentation and Summary of Significant    HTML     86K 
                Accounting Policies (Tables)                                     
50: R30         Financial Statement Details (Tables)                HTML    593K 
51: R31         Acquisitions, Divestitures, and Investments         HTML    118K 
                (Tables)                                                         
52: R32         Long-Term Debt Obligations (Tables)                 HTML    143K 
53: R33         Leases (Tables)                                     HTML    246K 
54: R34         Derivatives (Tables)                                HTML     71K 
55: R35         Fair Value Measurements (Tables)                    HTML    281K 
56: R36         Restructuring and Other Costs (Tables)              HTML     89K 
57: R37         Shareholders' Equity (Tables)                       HTML    199K 
58: R38         Earnings Per Share (Tables)                         HTML     94K 
59: R39         Income Taxes (Tables)                               HTML    420K 
60: R40         Segment Information (Tables)                        HTML    163K 
61: R41         Operations by Geographic Location (Tables)          HTML    112K 
62: R42         Share-Based Compensation (Tables)                   HTML    214K 
63: R43         Employee Benefit Plans (Tables)                     HTML     50K 
64: R44         Basis of Presentation and Summary of Significant    HTML    124K 
                Accounting Policies - Narrative (Details)                        
65: R45         Basis of Presentation and Summary of Significant    HTML     41K 
                Accounting Policies - Net Cash Pool Position                     
                (Details)                                                        
66: R46         Basis of Presentation and Summary of Significant    HTML     57K 
                Accounting Policies - Estimated Useful Lives of                  
                Property and Equipment (Details)                                 
67: R47         Basis of Presentation and Summary of Significant    HTML     49K 
                Accounting Policies - Estimated Useful Lives of                  
                Intangible Assets (Details)                                      
68: R48         Financial Statement Details - Accounts Receivable   HTML     59K 
                and Unbilled Services, net (Details)                             
69: R49         Financial Statement Details - Narrative (Details)   HTML     50K 
70: R50         Financial Statement Details - Schedule of Property  HTML     59K 
                and Equipment, Net (Details)                                     
71: R51         Financial Statement Details - Schedule of Goodwill  HTML     61K 
                (Details)                                                        
72: R52         Financial Statement Details - Schedule of           HTML     57K 
                Intangible Assets (Details)                                      
73: R53         Financial Statement Details - Schedule of Future    HTML     52K 
                Amortization Expense (Details)                                   
74: R54         Financial Statement Details - Schedule of Accrued   HTML     56K 
                Expenses (Details)                                               
75: R55         Financial Statement Details - Accumulated Other     HTML     54K 
                Comprehensive Loss, Net of Taxes (Details)                       
76: R56         Financial Statement Details - Tax Effects           HTML     61K 
                Allocated to Each Component of Other Comprehensive               
                (Loss) Income (Details)                                          
77: R57         Financial Statement Details - Schedule of Other     HTML     49K 
                (Income) Expense, Net (Details)                                  
78: R58         Financial Statement Details - Supplemental Cash     HTML     53K 
                Flow Information (Details)                                       
79: R59         Acquisitions, Divestitures, and Investments -       HTML    123K 
                Narrative (Details)                                              
80: R60         Acquisitions, Divestitures, and Investments -       HTML     52K 
                Preliminary Estimates of Fair Values of Intangible               
                Assets and Estimated Useful Lives (Details)                      
81: R61         Acquisitions, Divestitures, and Investments -       HTML     80K 
                Allocation of Consideration Transferred (Details)                
82: R62         Acquisitions, Divestitures, and Investments -       HTML     48K 
                Preliminary Estimates of Fair Value of Intangible                
                Assets and Estimated Useful Lives (Details)                      
83: R63         Long-Term Debt Obligations - Schedule of Debt       HTML     63K 
                Obligations (Details)                                            
84: R64         Long-Term Debt Obligations - Narrative (Details)    HTML    124K 
85: R65         Long-Term Debt Obligations - Schedule of Variable   HTML     63K 
                Rate Margins (Details)                                           
86: R66         Long-Term Debt Obligations - Accounts Receivable    HTML     66K 
                Financing Agreement (Details)                                    
87: R67         Long-Term Debt Obligations - Contractual            HTML     78K 
                Maturities of Debt Obligations (Details)                         
88: R68         Leases - Narrative (Details)                        HTML     40K 
89: R69         Leases - Components of Lease Cost (Details)         HTML     52K 
90: R70         Leases - Supplemental Balance Sheet Information     HTML     49K 
                Related to Leases (Details)                                      
91: R71         Leases - Supplemental Cash Flow Information         HTML     49K 
                Related to Leases (Details)                                      
92: R72         Leases - Supplemental Cash Flow Information,        HTML     45K 
                Weighted Average (Details)                                       
93: R73         Leases - Maturities of Lease Liabilities (Details)  HTML     92K 
94: R74         Derivatives - Narrative (Details)                   HTML     48K 
95: R75         Derivatives - Interest Rate Swaps Designated as     HTML     64K 
                Hedging Instruments on Consolidated Balance Sheets               
                (Details)                                                        
96: R76         Fair Value Measurements - Schedule of Assets and    HTML     78K 
                Liabilities Measured at Fair Value on a Recurring                
                Basis (Details)                                                  
97: R77         Fair Value Measurements - Schedule of Assets and    HTML     45K 
                Liabilities Measured at Fair Value on a Recurring                
                Basis (Parenthetical) (Details)                                  
98: R78         Fair Value Measurements - Reconciliation of         HTML     48K 
                Changes in the Carrying Amount of Contingent                     
                Consideration (Details)                                          
99: R79         Fair Value Measurements - Narrative (Details)       HTML     44K 
100: R80         Fair Value Measurements - Schedule of Estimated     HTML     60K  
                Fair Value (Details)                                             
101: R81         Restructuring and Other Costs - Schedule of         HTML     46K  
                Restructuring and other costs (Details)                          
102: R82         Restructuring and Other Costs - Liabilities         HTML     62K  
                Associated with Restructuring and Other Costs                    
                (Details)                                                        
103: R83         Shareholders' Equity - Shares of Common Stock       HTML     44K  
                Outstanding (Details)                                            
104: R84         Shareholders' Equity - Narrative (Details)          HTML     87K  
105: R85         Shareholders' Equity - Repurchase Activity          HTML     46K  
                (Details)                                                        
106: R86         Shareholders' Equity - Schedule of Stock by Class   HTML     59K  
                (Details)                                                        
107: R87         Earnings Per Share - Schedule of Earnings Per       HTML     75K  
                Share, Basic and Diluted (Details)                               
108: R88         Earnings Per Share - Narrative (Details)            HTML     38K  
109: R89         Income Taxes - Schedule of Components of Income     HTML     46K  
                before Provision for Income Taxes (Details)                      
110: R90         Income Taxes - Schedule of Components of Income     HTML     60K  
                Tax Expense (Benefit) (Details)                                  
111: R91         Income Taxes - Narrative (Details)                  HTML     79K  
112: R92         Income Taxes - Schedule of Effective Income Tax     HTML     83K  
                Rate Reconciliation (Details)                                    
113: R93         Income Taxes - Schedule of Effective Income Tax     HTML     43K  
                Rate Reconciliation (Parenthetical) (Details)                    
114: R94         Income Taxes - Summary of Valuation Allowance       HTML     53K  
                (Details)                                                        
115: R95         Income Taxes - Schedule of Deferred Tax Assets and  HTML     83K  
                Liabilities (Details)                                            
116: R96         Income Taxes - Schedule of Unrecognized Tax         HTML     54K  
                Benefits (Details)                                               
117: R97         Revenue from Contracts with Customers - Narrative   HTML     48K  
                (Details)                                                        
118: R98         Segment Information (Details)                       HTML     75K  
119: R99         Segment Information - Narrative (Details)           HTML     37K  
120: R100        Operations by Geographic Location - Total Revenue   HTML     64K  
                by Geographic Area (Details)                                     
121: R101        Operations by Geographic Location - Long-Lived      HTML     52K  
                Assets by Geographic Area (Details)                              
122: R102        Concentration of Credit Risk - Narrative (Details)  HTML     45K  
123: R103        Related-Party Transactions - Narrative (Details)    HTML     62K  
124: R104        Commitments and Contingencies - Narrative           HTML     52K  
                (Details)                                                        
125: R105        Share-Based Compensation - Narrative (Details)      HTML    101K  
126: R106        Share-Based Compensation - Stock Option Valuation   HTML     49K  
                Assumptions (Details)                                            
127: R107        Share-Based Compensation - Summary of Option        HTML     87K  
                Activity (Details)                                               
128: R108        Share-Based Compensation - Summary of Restricted    HTML     77K  
                Stock Unit Activity (Details)                                    
129: R109        Share-Based Compensation - Summary of Share-Based   HTML     43K  
                Compensation Expense (Details)                                   
130: R110        Employee Benefit Plans - Schedule of Contributions  HTML     38K  
                to Defined Contribution Plan (Details)                           
131: R111        Employee Benefit Plans - Narrative (Details)        HTML     50K  
134: XML         IDEA XML File -- Filing Summary                      XML    250K  
132: XML         XBRL Instance -- synh-20221231_htm                   XML   6.72M  
133: EXCEL       IDEA Workbook of Financial Reports                  XLSX    271K  
20: EX-101.CAL  XBRL Calculations -- synh-20221231_cal               XML    310K 
17: EX-101.DEF  XBRL Definitions -- synh-20221231_def                XML   1.22M 
18: EX-101.LAB  XBRL Labels -- synh-20221231_lab                     XML   2.35M 
16: EX-101.PRE  XBRL Presentations -- synh-20221231_pre              XML   1.89M 
19: EX-101.SCH  XBRL Schema -- synh-20221231                         XSD    298K 
135: JSON        XBRL Instance as JSON Data -- MetaLinks              752±  1.25M  
136: ZIP         XBRL Zipped Folder -- 0000950170-23-002928-xbrl      Zip   1.40M  


‘EX-101.DEF’   —   XBRL Definitions — synh-20221231_def


This Exhibit is an XBRL XML File.


                                                                                                                                                                                
<?xml version="1.0" encoding="windows-1252"?>
<!-- DFIN New ActiveDisclosure (SM) XBRL Linkbase Document - http://www.dfinsolutions.com/ -->
<!-- Creation Date :2023-02-15T16:16:48.3051+00:00 -->
<!-- Copyright (c) 2023 Donnelly Financial Solutions, Inc. All Rights Reserved. -->
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<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureFinancialStatementDetailsScheduleOfPropertyAndEquipmentNetDetails" xlink:href="synh-20221231.xsd#Role_DisclosureFinancialStatementDetailsScheduleOfPropertyAndEquipmentNetDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureFinancialStatementDetailsScheduleOfGoodwillDetails" xlink:href="synh-20221231.xsd#Role_DisclosureFinancialStatementDetailsScheduleOfGoodwillDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureFinancialStatementDetailsScheduleOfIntangibleAssetsDetails" xlink:href="synh-20221231.xsd#Role_DisclosureFinancialStatementDetailsScheduleOfIntangibleAssetsDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureFinancialStatementDetailsAccumulatedOtherComprehensiveLossNetOfTaxesDetails" xlink:href="synh-20221231.xsd#Role_DisclosureFinancialStatementDetailsAccumulatedOtherComprehensiveLossNetOfTaxesDetails" xlink:type="simple"/>
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<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureAcquisitionsDivestituresAndInvestmentsNarrativeDetails" xlink:href="synh-20221231.xsd#Role_DisclosureAcquisitionsDivestituresAndInvestmentsNarrativeDetails" xlink:type="simple"/>
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<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureLongTermDebtObligationsNarrativeDetails" xlink:href="synh-20221231.xsd#Role_DisclosureLongTermDebtObligationsNarrativeDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureLongTermDebtObligationsScheduleOfVariableRateMarginsDetails" xlink:href="synh-20221231.xsd#Role_DisclosureLongTermDebtObligationsScheduleOfVariableRateMarginsDetails" xlink:type="simple"/>
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<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureLeasesNarrativeDetails" xlink:href="synh-20221231.xsd#Role_DisclosureLeasesNarrativeDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureDerivativesNarrativeDetails" xlink:href="synh-20221231.xsd#Role_DisclosureDerivativesNarrativeDetails" xlink:type="simple"/>
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<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureFairValueMeasurementsScheduleOfEstimatedFairValueDetails" xlink:href="synh-20221231.xsd#Role_DisclosureFairValueMeasurementsScheduleOfEstimatedFairValueDetails" xlink:type="simple"/>
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<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureShareholdersEquitySharesOfCommonStockOutstandingDetails" xlink:href="synh-20221231.xsd#Role_DisclosureShareholdersEquitySharesOfCommonStockOutstandingDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureShareholdersEquityNarrativeDetails" xlink:href="synh-20221231.xsd#Role_DisclosureShareholdersEquityNarrativeDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureShareholdersEquityRepurchaseActivityDetails" xlink:href="synh-20221231.xsd#Role_DisclosureShareholdersEquityRepurchaseActivityDetails" xlink:type="simple"/>
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<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxesNarrativeDetails" xlink:href="synh-20221231.xsd#Role_DisclosureIncomeTaxesNarrativeDetails" xlink:type="simple"/>
<link:roleRef roleURI="http://www.syneoshealth.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxesScheduleOfEffectiveIncomeTaxRateReconciliationParentheticalDetails" xlink:href="synh-20221231.xsd#Role_DisclosureIncomeTaxesScheduleOfEffectiveIncomeTaxRateReconciliationParentheticalDetails" xlink:type="simple"/>
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<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ForeignPlanMember" xlink:label="us-gaap_ForeignPlanMember"/>
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<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetirementPlanSponsorLocationDomain" xlink:label="us-gaap_RetirementPlanSponsorLocationDomain_default"/>
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<link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredCompensationLiabilityClassifiedNoncurrent" xlink:label="us-gaap_DeferredCompensationLiabilityClassifiedNoncurrent"/>
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<link:definitionArc xlink:type="arc" order="0" xbrldt:closed="false" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="us-gaap_RetirementPlanSponsorLocationAxis" xlink:to="us-gaap_RetirementPlanSponsorLocationDomain" priority="2" use="optional"/>
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<link:definitionArc xlink:type="arc" order="1" xbrldt:closed="false" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="us-gaap_ScheduleOfDeferredCompensationArrangementWithIndividualExcludingShareBasedPaymentsAndPostretirementBenefitsByTitleOfIndividualAndByTypeOfDeferredCompensationTable" xlink:to="srt_RangeAxis" priority="2" use="optional"/>
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4 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 6/27/23  Syneos Health, Inc.               DEFM14A                1:2.4M                                   Donnelley … Solutions/FA
 6/27/23  Syneos Health, Inc.               PRER14A                2:2.5M                                   Donnelley … Solutions/FA
 6/15/23  Syneos Health, Inc.               PREM14A     6/14/23    2:2.3M                                   Donnelley … Solutions/FA
 5/10/23  Syneos Health, Inc.               10-Q        3/31/23   88:10M                                    Donnelley … Solutions/FA


30 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 1/09/23  Syneos Health, Inc.               8-K:2,5,9   1/05/23   13:295K                                   Donnelley … Solutions/FA
12/23/22  Syneos Health, Inc.               8-K:5,9    12/23/22   12:529K                                   ActiveDisclosure/FA
11/07/22  Syneos Health, Inc.               8-K:1,2,9  11/04/22   11:2.5M                                   ActiveDisclosure/FA
11/04/22  Syneos Health, Inc.               10-Q        9/30/22   87:14M                                    Donnelley … Solutions/FA
 8/02/22  Syneos Health, Inc.               10-Q        6/30/22   87:12M                                    Donnelley … Solutions/FA
 6/01/22  Syneos Health, Inc.               8-K:5,8,9   5/25/22   13:605K                                   ActiveDisclosure/FA
 4/29/22  Syneos Health, Inc.               8-K:5,9     4/28/22   14:887K                                   ActiveDisclosure/FA
 4/29/22  Syneos Health, Inc.               10-Q        3/31/22   85:9M                                     ActiveDisclosure/FA
 2/17/22  Syneos Health, Inc.               10-K       12/31/21  134:25M                                    ActiveDisclosure/FA
11/03/21  Syneos Health, Inc.               10-Q        9/30/21   88:13M                                    ActiveDisclosure/FA
 8/09/21  Syneos Health, Inc.               10-Q        6/30/21   86:11M                                    ActiveDisclosure/FA
 2/18/21  Syneos Health, Inc.               10-K       12/31/20  130:23M                                    ActiveDisclosure/FA
 1/21/21  Syneos Health, Inc.               8-K:5,9     1/14/21   12:948K                                   ActiveDisclosure/FA
11/25/20  Syneos Health, Inc.               8-K:1,2,8,911/24/20   14:2.7M                                   Donnelley … Solutions/FA
10/29/20  Syneos Health, Inc.               10-Q        9/30/20   88:13M                                    ActiveDisclosure/FA
 4/30/20  Syneos Health, Inc.               10-Q        3/31/20   83:7.6M
 2/20/20  Syneos Health, Inc.               10-K       12/31/19  137:20M
10/31/19  Syneos Health, Inc.               10-Q        9/30/19   94:14M
 8/06/19  Syneos Health, Inc.               10-Q        6/30/19   95:17M
 3/18/19  Syneos Health, Inc.               10-K       12/31/18  136:18M
11/06/18  Syneos Health, Inc.               10-Q        9/30/18   98:12M
 8/02/18  Syneos Health, Inc.               10-Q        6/30/18   94:14M
 6/29/18  Syneos Health, Inc.               8-K:1,2,9   6/29/18    3:934K                                   Donnelley … Solutions/FA
 5/25/18  Syneos Health, Inc.               8-K:5,9     5/24/18    3:217K                                   Donnelley … Solutions/FA
 5/09/18  Syneos Health, Inc.               10-Q        3/31/18   92:8.3M
 1/08/18  Syneos Health, Inc.               8-K:5,7,9   1/04/18    4:156K                                   Donnelley … Solutions/FA
 8/01/17  Syneos Health, Inc.               8-K:1,2,5,8 8/01/17    8:3.7M                                   Donnelley … Solutions/FA
 4/06/17  Syneos Health, Inc.               8-K:5,9     4/01/17    2:76K
 7/28/16  Syneos Health, Inc.               8-K:5,9     7/27/16    6:393K                                   Donnelley … Solutions/FA
10/27/14  Syneos Health, Inc.               S-1/A                  6:4.5M                                   Toppan Merrill-FA
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