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Ownership Document
|
| Schema Version: X0508 |
| Document Type: 4 |
| Period of Report: 2/1/24 |
| Not Subject to Section 16: 0 |
| Issuer: |
| Issuer CIK: 874015 |
| Issuer Name: IONIS PHARMACEUTICALS INC |
| Issuer Trading Symbol: IONS |
| Reporting Owner: |
| Reporting Owner ID: |
| | Owner CIK: 1074773 |
| | Owner Name: HOUGEN ELIZABETH L |
| Reporting Owner Address: |
| | Owner Street 1: 2855 GAZELLE COURT |
| | Owner Street 2: |
| | Owner City: CARLSBAD |
| | Owner State: CA |
| | Owner ZIP Code: 92010 |
| | Owner State Description: |
| Reporting Owner Relationship: |
| | Is Director? No |
| | Is Officer? Yes |
| | Is Ten Percent Owner? No |
| | Is Other? No |
| | Officer Title: EVP, Finance & CFO |
| Aff 10b5 One: 0 |
| Non-Derivative Table: |
| Non-Derivative Transaction: |
| | Security Title: |
| | | Value: Common Stock |
| | Transaction Date: |
| | | Value: 2/1/24 |
| | Transaction Coding: |
| | | Transaction Form Type: 4 |
| | | Transaction Code: A |
| | | Equity Swap Involved? No |
| | Transaction Amounts: |
| | | Transaction Shares: |
| Value: 4,140 |
| Footnote ID: F1 |
| | | Transaction Price Per Share: |
| Value: 0.0 |
| | | Transaction Acquired-Disposed Code: |
| Value: A |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 95,030 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: D |
| Non-Derivative Transaction: |
| | Security Title: |
| | | Value: Common Stock |
| | Transaction Date: |
| | | Value: 2/2/24 |
| | Transaction Coding: |
| | | Transaction Form Type: 4 |
| | | Transaction Code: S |
| | | Equity Swap Involved? No |
| | Transaction Amounts: |
| | | Transaction Shares: |
| Value: 2,125 |
| Footnote ID: F2 |
| | | Transaction Price Per Share: |
| Value: 49.5399 |
| Footnote ID: F3 |
| | | Transaction Acquired-Disposed Code: |
| Value: D |
| | Post-Transaction Amounts: |
| | | Shares Owned Following Transaction: |
| Value: 92,905 |
| | Ownership Nature: |
| | | Direct or Indirect Ownership: |
| Value: D |
| Footnotes: |
| Footnote - F1: Represents shares earned upon the vesting of performance-based restricted stock units ("PRSUs") for the second performance period of the grant to the reporting person reported on January 19, 2022. The Compensation Committee certified achievement of the pre-established performance goal based on the Issuer's relative total shareholder return as compared to a peer group of companies at a level resulting in a vest of 150% of target shares. As reported at grant, the PRSUs could result in a payout of 0% to 150% based on actual achievement of the goal. |
| Footnote - F2: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Performance restricted Stock Unit Agreement and Grant Notice. |
| Footnote - F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.53 to $49.55 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4. |
| Owner Signature: |
| Signature Name: By: Patrick R. O'Neil, attorney-in-fact For: Elizabeth L. Hougen |
| Signature Date: 2/2/24 |
