| | | | | | | | | | | | | | | | | | | | | |
<?xml version="1.0" encoding="windows-1252"?> |
<!-- Generated by Thomson Reuters Accelus --> |
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xbrli="http://www.xbrl.org/2003/instance"> |
| <link:roleRef roleURI="http://cytrx.com/role/DocumentAndEntityInformation" xlink:type="simple" xlink:href="cytr-20111231.xsd#DocumentAndEntityInformation"/> |
| <link:roleRef roleURI="http://cytrx.com/role/ScheduleIiValuationAndQualifyingAccounts" xlink:type="simple" xlink:href="cytr-20111231.xsd#ScheduleIiValuationAndQualifyingAccounts"/> |
| <link:roleRef roleURI="http://cytrx.com/role/SubsequentEvents" xlink:type="simple" xlink:href="cytr-20111231.xsd#SubsequentEvents"/> |
| <link:roleRef roleURI="http://cytrx.com/role/QuarterlyFinancialDataUnaudited" xlink:type="simple" xlink:href="cytr-20111231.xsd#QuarterlyFinancialDataUnaudited"/> |
| <link:roleRef roleURI="http://cytrx.com/role/IncomeTaxes" xlink:type="simple" xlink:href="cytr-20111231.xsd#IncomeTaxes"/> |
| <link:roleRef roleURI="http://cytrx.com/role/StockholderProtectionRightsPlan" xlink:type="simple" xlink:href="cytr-20111231.xsd#StockholderProtectionRightsPlan"/> |
| <link:roleRef roleURI="http://cytrx.com/role/AlscrtAmendment" xlink:type="simple" xlink:href="cytr-20111231.xsd#AlscrtAmendment"/> |
| <link:roleRef roleURI="http://cytrx.com/role/SaleOfAssets" xlink:type="simple" xlink:href="cytr-20111231.xsd#SaleOfAssets"/> |
| <link:roleRef roleURI="http://cytrx.com/role/StockOptionsAndWarrants" xlink:type="simple" xlink:href="cytr-20111231.xsd#StockOptionsAndWarrants"/> |
| <link:roleRef roleURI="http://cytrx.com/role/InvestmentsInRxiAndAdventrxPharmaceuticals" xlink:type="simple" xlink:href="cytr-20111231.xsd#InvestmentsInRxiAndAdventrxPharmaceuticals"/> |
| <link:roleRef roleURI="http://cytrx.com/role/EquityTransactions" xlink:type="simple" xlink:href="cytr-20111231.xsd#EquityTransactions"/> |
| <link:roleRef roleURI="http://cytrx.com/role/CommitmentsAndContingencies" xlink:type="simple" xlink:href="cytr-20111231.xsd#CommitmentsAndContingencies"/> |
| <link:roleRef roleURI="http://cytrx.com/role/WarrantLiabilities" xlink:type="simple" xlink:href="cytr-20111231.xsd#WarrantLiabilities"/> |
| <link:roleRef roleURI="http://cytrx.com/role/AccruedExpensesAndOtherCurrentLiabilities" xlink:type="simple" xlink:href="cytr-20111231.xsd#AccruedExpensesAndOtherCurrentLiabilities"/> |
| <link:roleRef roleURI="http://cytrx.com/role/EquipmentAndFurnishings" xlink:type="simple" xlink:href="cytr-20111231.xsd#EquipmentAndFurnishings"/> |
| <link:roleRef roleURI="http://cytrx.com/role/MarketableSecurities" xlink:type="simple" xlink:href="cytr-20111231.xsd#MarketableSecurities"/> |
| <link:roleRef roleURI="http://cytrx.com/role/PrepaidAndOtherAssets" xlink:type="simple" xlink:href="cytr-20111231.xsd#PrepaidAndOtherAssets"/> |
| <link:roleRef roleURI="http://cytrx.com/role/Receivable" xlink:type="simple" xlink:href="cytr-20111231.xsd#Receivable"/> |
| <link:roleRef roleURI="http://cytrx.com/role/RecentAccountingPronouncements" xlink:type="simple" xlink:href="cytr-20111231.xsd#RecentAccountingPronouncements"/> |
| <link:roleRef roleURI="http://cytrx.com/role/SummaryOfSignificantAccountingPolicies" xlink:type="simple" xlink:href="cytr-20111231.xsd#SummaryOfSignificantAccountingPolicies"/> |
| <link:roleRef roleURI="http://cytrx.com/role/NatureOfBusiness" xlink:type="simple" xlink:href="cytr-20111231.xsd#NatureOfBusiness"/> |
| <link:roleRef roleURI="http://cytrx.com/role/ConsolidatedStatementsOfCashFlows" xlink:type="simple" xlink:href="cytr-20111231.xsd#ConsolidatedStatementsOfCashFlows"/> |
| <link:roleRef roleURI="http://cytrx.com/role/ConsolidatedStatementsOfStockholdersEquity" xlink:type="simple" xlink:href="cytr-20111231.xsd#ConsolidatedStatementsOfStockholdersEquity"/> |
| <link:roleRef roleURI="http://cytrx.com/role/ConsolidatedStatementsOfOperations" xlink:type="simple" xlink:href="cytr-20111231.xsd#ConsolidatedStatementsOfOperations"/> |
| <link:roleRef roleURI="http://cytrx.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="cytr-20111231.xsd#ConsolidatedBalanceSheetsParenthetical"/> |
| <link:roleRef roleURI="http://cytrx.com/role/ConsolidatedBalanceSheets" xlink:type="simple" xlink:href="cytr-20111231.xsd#ConsolidatedBalanceSheets"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/ConsolidatedBalanceSheets"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="LiabilitiesAndStockholdersEquity" xlink:title="LiabilitiesAndStockholdersEquity"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="LiabilitiesCurrent" xlink:title="LiabilitiesCurrent"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_DerivativeLiabilitiesCurrent" xlink:label="DerivativeLiabilitiesCurrent" xlink:title="DerivativeLiabilitiesCurrent"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="LiabilitiesCurrent" xlink:to="DerivativeLiabilitiesCurrent" xlink:title="calculation: LiabilitiesCurrent to DerivativeLiabilitiesCurrent" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_AccountsPayableAndOtherAccruedLiabilitiesCurrent" xlink:label="AccountsPayableAndOtherAccruedLiabilitiesCurrent" xlink:title="AccountsPayableAndOtherAccruedLiabilitiesCurrent"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="LiabilitiesCurrent" xlink:to="AccountsPayableAndOtherAccruedLiabilitiesCurrent" xlink:title="calculation: LiabilitiesCurrent to AccountsPayableAndOtherAccruedLiabilitiesCurrent" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_AccountsPayableCurrent" xlink:label="AccountsPayableCurrent" xlink:title="AccountsPayableCurrent"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="LiabilitiesCurrent" xlink:to="AccountsPayableCurrent" xlink:title="calculation: LiabilitiesCurrent to AccountsPayableCurrent" order="3.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="LiabilitiesAndStockholdersEquity" xlink:to="LiabilitiesCurrent" xlink:title="calculation: LiabilitiesAndStockholdersEquity to LiabilitiesCurrent" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="StockholdersEquity" xlink:title="StockholdersEquity"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="RetainedEarningsAccumulatedDeficit" xlink:title="RetainedEarningsAccumulatedDeficit"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="StockholdersEquity" xlink:to="RetainedEarningsAccumulatedDeficit" xlink:title="calculation: StockholdersEquity to RetainedEarningsAccumulatedDeficit" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_TreasuryStockValue" xlink:label="TreasuryStockValue" xlink:title="TreasuryStockValue"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="StockholdersEquity" xlink:to="TreasuryStockValue" xlink:title="calculation: StockholdersEquity to TreasuryStockValue" order="2.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="AdditionalPaidInCapital" xlink:title="AdditionalPaidInCapital"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="StockholdersEquity" xlink:to="AdditionalPaidInCapital" xlink:title="calculation: StockholdersEquity to AdditionalPaidInCapital" order="3.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_CommonStockValue" xlink:label="CommonStockValue" xlink:title="CommonStockValue"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="StockholdersEquity" xlink:to="CommonStockValue" xlink:title="calculation: StockholdersEquity to CommonStockValue" order="4.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_PreferredStockValue" xlink:label="PreferredStockValue" xlink:title="PreferredStockValue"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="StockholdersEquity" xlink:to="PreferredStockValue" xlink:title="calculation: StockholdersEquity to PreferredStockValue" order="5.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="LiabilitiesAndStockholdersEquity" xlink:to="StockholdersEquity" xlink:title="calculation: LiabilitiesAndStockholdersEquity to StockholdersEquity" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_Assets" xlink:label="Assets" xlink:title="Assets"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="OtherAssetsNoncurrent" xlink:title="OtherAssetsNoncurrent"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="Assets" xlink:to="OtherAssetsNoncurrent" xlink:title="calculation: Assets to OtherAssetsNoncurrent" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_Goodwill" xlink:label="Goodwill" xlink:title="Goodwill"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="Assets" xlink:to="Goodwill" xlink:title="calculation: Assets to Goodwill" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="PropertyPlantAndEquipmentNet" xlink:title="PropertyPlantAndEquipmentNet"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="Assets" xlink:to="PropertyPlantAndEquipmentNet" xlink:title="calculation: Assets to PropertyPlantAndEquipmentNet" order="3.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="AssetsCurrent" xlink:title="AssetsCurrent"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="PrepaidExpenseAndOtherAssetsCurrent" xlink:title="PrepaidExpenseAndOtherAssetsCurrent"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AssetsCurrent" xlink:to="PrepaidExpenseAndOtherAssetsCurrent" xlink:title="calculation: AssetsCurrent to PrepaidExpenseAndOtherAssetsCurrent" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_InterestReceivable" xlink:label="InterestReceivable" xlink:title="InterestReceivable"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AssetsCurrent" xlink:to="InterestReceivable" xlink:title="calculation: AssetsCurrent to InterestReceivable" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="IncomeTaxesReceivable" xlink:title="IncomeTaxesReceivable"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AssetsCurrent" xlink:to="IncomeTaxesReceivable" xlink:title="calculation: AssetsCurrent to IncomeTaxesReceivable" order="3.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ReceivablesNetCurrent" xlink:label="ReceivablesNetCurrent" xlink:title="ReceivablesNetCurrent"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AssetsCurrent" xlink:to="ReceivablesNetCurrent" xlink:title="calculation: AssetsCurrent to ReceivablesNetCurrent" order="4.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="cytr-20111231.xsd#cytr_ProceedsFromSaleOfRxi" xlink:label="ProceedsFromSaleOfRxi" xlink:title="ProceedsFromSaleOfRxi"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AssetsCurrent" xlink:to="ProceedsFromSaleOfRxi" xlink:title="calculation: AssetsCurrent to ProceedsFromSaleOfRxi" order="5.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_AvailableForSaleSecuritiesCurrent" xlink:label="AvailableForSaleSecuritiesCurrent" xlink:title="AvailableForSaleSecuritiesCurrent"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AssetsCurrent" xlink:to="AvailableForSaleSecuritiesCurrent" xlink:title="calculation: AssetsCurrent to AvailableForSaleSecuritiesCurrent" order="6.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="CashAndCashEquivalentsAtCarryingValue" xlink:title="CashAndCashEquivalentsAtCarryingValue"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AssetsCurrent" xlink:to="CashAndCashEquivalentsAtCarryingValue" xlink:title="calculation: AssetsCurrent to CashAndCashEquivalentsAtCarryingValue" order="7.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="Assets" xlink:to="AssetsCurrent" xlink:title="calculation: Assets to AssetsCurrent" order="4.0" weight="1.0"/> |
| | </link:calculationLink> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/ConsolidatedBalanceSheetsParenthetical"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/ConsolidatedStatementsOfOperations"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:label="IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:title="IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:title="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_GainLossOnSaleOfEquityInvestments" xlink:label="GainLossOnSaleOfEquityInvestments" xlink:title="GainLossOnSaleOfEquityInvestments"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="GainLossOnSaleOfEquityInvestments" xlink:title="calculation: IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest to GainLossOnSaleOfEquityInvestments" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_DerivativeGainLossOnDerivativeNet" xlink:label="DerivativeGainLossOnDerivativeNet" xlink:title="DerivativeGainLossOnDerivativeNet"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="DerivativeGainLossOnDerivativeNet" xlink:title="calculation: IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest to DerivativeGainLossOnDerivativeNet" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_OtherNonoperatingIncome" xlink:label="OtherNonoperatingIncome" xlink:title="OtherNonoperatingIncome"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="OtherNonoperatingIncome" xlink:title="calculation: IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest to OtherNonoperatingIncome" order="3.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_InvestmentIncomeInterestAndDividend" xlink:label="InvestmentIncomeInterestAndDividend" xlink:title="InvestmentIncomeInterestAndDividend"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="InvestmentIncomeInterestAndDividend" xlink:title="calculation: IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest to InvestmentIncomeInterestAndDividend" order="4.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="OperatingIncomeLoss" xlink:title="OperatingIncomeLoss"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_OperatingExpenses" xlink:label="OperatingExpenses" xlink:title="OperatingExpenses"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_DepreciationAndAmortization" xlink:label="DepreciationAndAmortization" xlink:title="DepreciationAndAmortization"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="OperatingExpenses" xlink:to="DepreciationAndAmortization" xlink:title="calculation: OperatingExpenses to DepreciationAndAmortization" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="GeneralAndAdministrativeExpense" xlink:title="GeneralAndAdministrativeExpense"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="OperatingExpenses" xlink:to="GeneralAndAdministrativeExpense" xlink:title="calculation: OperatingExpenses to GeneralAndAdministrativeExpense" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="ResearchAndDevelopmentExpense" xlink:title="ResearchAndDevelopmentExpense"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="OperatingExpenses" xlink:to="ResearchAndDevelopmentExpense" xlink:title="calculation: OperatingExpenses to ResearchAndDevelopmentExpense" order="3.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="OperatingIncomeLoss" xlink:to="OperatingExpenses" xlink:title="calculation: OperatingIncomeLoss to OperatingExpenses" order="1.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_SalesRevenueNet" xlink:label="SalesRevenueNet" xlink:title="SalesRevenueNet"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_LicensesRevenue" xlink:label="LicensesRevenue" xlink:title="LicensesRevenue"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="SalesRevenueNet" xlink:to="LicensesRevenue" xlink:title="calculation: SalesRevenueNet to LicensesRevenue" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_SalesRevenueServicesNet" xlink:label="SalesRevenueServicesNet" xlink:title="SalesRevenueServicesNet"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="SalesRevenueNet" xlink:to="SalesRevenueServicesNet" xlink:title="calculation: SalesRevenueNet to SalesRevenueServicesNet" order="2.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="OperatingIncomeLoss" xlink:to="SalesRevenueNet" xlink:title="calculation: OperatingIncomeLoss to SalesRevenueNet" order="2.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="OperatingIncomeLoss" xlink:title="calculation: IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest to OperatingIncomeLoss" order="5.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:to="IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:title="calculation: IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest to IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="IncomeTaxExpenseBenefit" xlink:title="IncomeTaxExpenseBenefit"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:to="IncomeTaxExpenseBenefit" xlink:title="calculation: IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest to IncomeTaxExpenseBenefit" order="2.0" weight="-1.0"/> |
| | </link:calculationLink> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/ConsolidatedStatementsOfStockholdersEquity"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/ConsolidatedStatementsOfCashFlows"> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:label="CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:title="CashAndCashEquivalentsPeriodIncreaseDecrease"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="NetCashProvidedByUsedInFinancingActivities" xlink:title="NetCashProvidedByUsedInFinancingActivities"/> |
| | <link:loc xlink:type="locator" xlink:href="cytr-20111231.xsd#cytr_CommonStockIssuedInAccordanceWithFinancing" xlink:label="CommonStockIssuedInAccordanceWithFinancing" xlink:title="CommonStockIssuedInAccordanceWithFinancing"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInFinancingActivities" xlink:to="CommonStockIssuedInAccordanceWithFinancing" xlink:title="calculation: NetCashProvidedByUsedInFinancingActivities to CommonStockIssuedInAccordanceWithFinancing" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="ProceedsFromStockOptionsExercised" xlink:title="ProceedsFromStockOptionsExercised"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInFinancingActivities" xlink:to="ProceedsFromStockOptionsExercised" xlink:title="calculation: NetCashProvidedByUsedInFinancingActivities to ProceedsFromStockOptionsExercised" order="2.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:to="NetCashProvidedByUsedInFinancingActivities" xlink:title="calculation: CashAndCashEquivalentsPeriodIncreaseDecrease to NetCashProvidedByUsedInFinancingActivities" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="NetCashProvidedByUsedInInvestingActivities" xlink:title="NetCashProvidedByUsedInInvestingActivities"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities" xlink:label="ProceedsFromSaleAndMaturityOfMarketableSecurities" xlink:title="ProceedsFromSaleAndMaturityOfMarketableSecurities"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInInvestingActivities" xlink:to="ProceedsFromSaleAndMaturityOfMarketableSecurities" xlink:title="calculation: NetCashProvidedByUsedInInvestingActivities to ProceedsFromSaleAndMaturityOfMarketableSecurities" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_PaymentsToAcquireMarketableSecurities" xlink:label="PaymentsToAcquireMarketableSecurities" xlink:title="PaymentsToAcquireMarketableSecurities"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInInvestingActivities" xlink:to="PaymentsToAcquireMarketableSecurities" xlink:title="calculation: NetCashProvidedByUsedInInvestingActivities to PaymentsToAcquireMarketableSecurities" order="2.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:title="ProceedsFromSaleOfPropertyPlantAndEquipment"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInInvestingActivities" xlink:to="ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:title="calculation: NetCashProvidedByUsedInInvestingActivities to ProceedsFromSaleOfPropertyPlantAndEquipment" order="3.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="cytr-20111231.xsd#cytr_ProceedsFromSaleOfAssetsHeldForSale" xlink:label="ProceedsFromSaleOfAssetsHeldForSale" xlink:title="ProceedsFromSaleOfAssetsHeldForSale"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInInvestingActivities" xlink:to="ProceedsFromSaleOfAssetsHeldForSale" xlink:title="calculation: NetCashProvidedByUsedInInvestingActivities to ProceedsFromSaleOfAssetsHeldForSale" order="4.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ProceedsFromSaleOfEquityMethodInvestments" xlink:label="ProceedsFromSaleOfEquityMethodInvestments" xlink:title="ProceedsFromSaleOfEquityMethodInvestments"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInInvestingActivities" xlink:to="ProceedsFromSaleOfEquityMethodInvestments" xlink:title="calculation: NetCashProvidedByUsedInInvestingActivities to ProceedsFromSaleOfEquityMethodInvestments" order="5.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="PaymentsToAcquirePropertyPlantAndEquipment" xlink:title="PaymentsToAcquirePropertyPlantAndEquipment"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInInvestingActivities" xlink:to="PaymentsToAcquirePropertyPlantAndEquipment" xlink:title="calculation: NetCashProvidedByUsedInInvestingActivities to PaymentsToAcquirePropertyPlantAndEquipment" order="6.0" weight="-1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:to="NetCashProvidedByUsedInInvestingActivities" xlink:title="calculation: CashAndCashEquivalentsPeriodIncreaseDecrease to NetCashProvidedByUsedInInvestingActivities" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="NetCashProvidedByUsedInOperatingActivities" xlink:title="NetCashProvidedByUsedInOperatingActivities"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:label="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:title="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet" xlink:label="IncreaseDecreaseInAccruedInterestReceivableNet" xlink:title="IncreaseDecreaseInAccruedInterestReceivableNet"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="IncreaseDecreaseInAccruedInterestReceivableNet" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to IncreaseDecreaseInAccruedInterestReceivableNet" order="1.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="ShareBasedCompensation" xlink:title="ShareBasedCompensation"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="ShareBasedCompensation" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to ShareBasedCompensation" order="2.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="IncreaseDecreaseInAccountsReceivable" xlink:title="IncreaseDecreaseInAccountsReceivable"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="IncreaseDecreaseInAccountsReceivable" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to IncreaseDecreaseInAccountsReceivable" order="3.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:label="IncreaseDecreaseInIncomeTaxesReceivable" xlink:title="IncreaseDecreaseInIncomeTaxesReceivable"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="IncreaseDecreaseInIncomeTaxesReceivable" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to IncreaseDecreaseInIncomeTaxesReceivable" order="4.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:title="IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" order="5.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="IncreaseDecreaseInAccountsPayable" xlink:title="IncreaseDecreaseInAccountsPayable"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="IncreaseDecreaseInAccountsPayable" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to IncreaseDecreaseInAccountsPayable" order="6.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:label="IncreaseDecreaseInDeferredRevenue" xlink:title="IncreaseDecreaseInDeferredRevenue"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="IncreaseDecreaseInDeferredRevenue" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to IncreaseDecreaseInDeferredRevenue" order="7.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:label="IncreaseDecreaseInAccruedLiabilities" xlink:title="IncreaseDecreaseInAccruedLiabilities"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="IncreaseDecreaseInAccruedLiabilities" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to IncreaseDecreaseInAccruedLiabilities" order="8.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="DepreciationDepletionAndAmortization" xlink:title="DepreciationDepletionAndAmortization"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="DepreciationDepletionAndAmortization" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to DepreciationDepletionAndAmortization" order="9.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_GainLossOnDispositionOfAssets" xlink:label="GainLossOnDispositionOfAssets" xlink:title="GainLossOnDispositionOfAssets"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="GainLossOnDispositionOfAssets" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to GainLossOnDispositionOfAssets" order="10.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_DerivativeGainLossOnDerivativeNet" xlink:label="DerivativeGainLossOnDerivativeNet" xlink:title="DerivativeGainLossOnDerivativeNet"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="DerivativeGainLossOnDerivativeNet" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to DerivativeGainLossOnDerivativeNet" order="11.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="AssetImpairmentCharges" xlink:title="AssetImpairmentCharges"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="AssetImpairmentCharges" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to AssetImpairmentCharges" order="12.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossUnrealized" xlink:label="ForeignCurrencyTransactionGainLossUnrealized" xlink:title="ForeignCurrencyTransactionGainLossUnrealized"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="ForeignCurrencyTransactionGainLossUnrealized" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to ForeignCurrencyTransactionGainLossUnrealized" order="13.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_GainLossOnSaleOfEquityInvestments" xlink:label="GainLossOnSaleOfEquityInvestments" xlink:title="GainLossOnSaleOfEquityInvestments"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="GainLossOnSaleOfEquityInvestments" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to GainLossOnSaleOfEquityInvestments" order="14.0" weight="-1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_ShareBasedGoodsAndNonemployeeServicesTransactionCashFlowEffects" xlink:label="ShareBasedGoodsAndNonemployeeServicesTransactionCashFlowEffects" xlink:title="ShareBasedGoodsAndNonemployeeServicesTransactionCashFlowEffects"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:to="ShareBasedGoodsAndNonemployeeServicesTransactionCashFlowEffects" xlink:title="calculation: AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities to ShareBasedGoodsAndNonemployeeServicesTransactionCashFlowEffects" order="15.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInOperatingActivities" xlink:to="AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:title="calculation: NetCashProvidedByUsedInOperatingActivities to AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" order="1.0" weight="1.0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="NetIncomeLoss" xlink:title="NetIncomeLoss"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="NetCashProvidedByUsedInOperatingActivities" xlink:to="NetIncomeLoss" xlink:title="calculation: NetCashProvidedByUsedInOperatingActivities to NetIncomeLoss" order="2.0" weight="1.0"/> |
| | <link:calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:to="NetCashProvidedByUsedInOperatingActivities" xlink:title="calculation: CashAndCashEquivalentsPeriodIncreaseDecrease to NetCashProvidedByUsedInOperatingActivities" order="3.0" weight="1.0"/> |
| | </link:calculationLink> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/NatureOfBusiness"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/SummaryOfSignificantAccountingPolicies"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/RecentAccountingPronouncements"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/Receivable"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/PrepaidAndOtherAssets"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/MarketableSecurities"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/EquipmentAndFurnishings"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/AccruedExpensesAndOtherCurrentLiabilities"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/WarrantLiabilities"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/CommitmentsAndContingencies"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/EquityTransactions"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/InvestmentsInRxiAndAdventrxPharmaceuticals"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/StockOptionsAndWarrants"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/SaleOfAssets"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/AlscrtAmendment"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/StockholderProtectionRightsPlan"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/IncomeTaxes"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/QuarterlyFinancialDataUnaudited"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/SubsequentEvents"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/ScheduleIiValuationAndQualifyingAccounts"/> |
| <link:calculationLink xlink:type="extended" xlink:role="http://cytrx.com/role/DocumentAndEntityInformation"/> |
| </link:linkbase> |