SEC Info  
    Home      Search      My Interests      Help      Sign In      Please Sign In

Henry Schein Inc. – ‘10-Q’ for 3/27/21 – ‘EX-101.PRE’

On:  Tuesday, 5/4/21, at 4:29pm ET   ·   For:  3/27/21   ·   Accession #:  1000228-21-36   ·   File #:  0-27078

Previous ‘10-Q’:  ‘10-Q’ on 11/2/20 for 9/26/20   ·   Next:  ‘10-Q’ on 8/3/21 for 6/26/21   ·   Latest:  ‘10-Q’ on 11/28/23 for 9/30/23   ·   4 References:   

Find Words in Filings emoji
 
  in    Show  and   Hints

  As Of               Filer                 Filing    For·On·As Docs:Size

 5/04/21  Henry Schein Inc.                 10-Q        3/27/21   89:8.6M

Quarterly Report   —   Form 10-Q
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-Q        The 1Q21 Quarterly 10-Q Report                      HTML   1.75M 
 2: EX-10.2     Material Contract -- exhibit102                     HTML    145K 
 3: EX-31.1     Certification -- §302 - SOA'02 -- exhibit311        HTML     37K 
 4: EX-31.2     Certification -- §302 - SOA'02 -- exhibit312        HTML     37K 
 5: EX-32.1     Certification -- §906 - SOA'02 -- exhibit321        HTML     32K 
12: R1          Cover Page                                          HTML     76K 
13: R2          Consolidated Balance Sheets (Unaudited)             HTML    135K 
14: R3          Consolidated Balance Sheets (Parenthetical)         HTML     40K 
15: R4          Consolidated Statements of Income (Unaudited)       HTML    145K 
16: R5          Consolidated Statements of Comprehensive Income     HTML     68K 
                (Unaudited)                                                      
17: R6          Consolidated Statements of Changes in               HTML    101K 
                Stockholders' Equity (Unaudited)                                 
18: R7          Consolidated Statements of Changes in               HTML     40K 
                Stockholders' Equity (Unaudited) (Parenthetical)                 
19: R8          Consolidated Statements of Cash Flows (Unaudited)   HTML    151K 
20: R9          Basis of Presentation                               HTML     47K 
21: R10         Critical Accounting Policies, Accounting            HTML     41K 
                Pronouncements Adopted and Recently Issued                       
                Accounting Standards                                             
22: R11         Revenue from Contracts with Customers               HTML     50K 
23: R12         Segment Data                                        HTML     47K 
24: R13         Debt                                                HTML     82K 
25: R14         Leases                                              HTML     63K 
26: R15         Redeemable Noncontrolling Interests                 HTML     35K 
27: R16         Comprehensive Income                                HTML     55K 
28: R17         Fair Value Measurements                             HTML     65K 
29: R18         Business Acquisitions                               HTML     42K 
30: R19         Plans of Restructuring                              HTML     52K 
31: R20         Earnings Per Share                                  HTML     32K 
32: R21         Income Taxes                                        HTML     45K 
33: R22         Derivatives and Hedging Activities                  HTML     45K 
34: R23         Stock-Based Compensation                            HTML     79K 
35: R24         Supplemental Cash Flow Information                  HTML     30K 
36: R25         Legal Proceedings                                   HTML     76K 
37: R26         Related Party Transactions                          HTML     45K 
38: R27         Critical Accounting Policies, Accounting            HTML     67K 
                Pronouncements Adopted and Recently Issued                       
                Accounting Standards (Policies)                                  
39: R28         Revenue from Contracts with Customers (Tables)      HTML     41K 
40: R29         Segment Data (Tables)                               HTML     37K 
41: R30         Debt (Tables)                                       HTML     54K 
42: R31         Leases (Tables)                                     HTML     70K 
43: R32         Redeemable Noncontrolling Interests (Tables)        HTML     33K 
44: R33         Comprehensive Income (Tables)                       HTML     53K 
45: R34         Fair Value Measurements (Tables)                    HTML     47K 
46: R35         Plans of Restructuring (Tables)                     HTML     48K 
47: R36         Earnings Per Share (Tables)                         HTML     28K 
48: R37         Stock-Based Compensation (Tables)                   HTML     52K 
49: R38         Supplemental Cash Flow Information (Tables)         HTML     28K 
50: R39         Basis of Presentation - Narrative (Details)         HTML     34K 
51: R40         Critical Accounting Policies, Accounting            HTML     38K 
                Pronouncements Adopted and Recently Issued                       
                Accounting Standards - Narrative (Details)                       
52: R41         Revenue from Contracts with Customers -             HTML     60K 
                Disaggregation of Revenue (Details)                              
53: R42         Revenue from Contracts with Customers - Contract    HTML     31K 
                Balances (Details)                                               
54: R43         Segment Data (Details)                              HTML     52K 
55: R44         Debt - Bank credit lines (Details)                  HTML     30K 
56: R45         Debt - Revolving Credit Agreement, 364-Day Credit   HTML     53K 
                Agreement and Other Short-Term Credit Lines                      
                Narrative (Details)                                              
57: R46         Debt - Long-term Debt (Details)                     HTML     47K 
58: R47         Debt - Private Placement Facilities - Narrative     HTML     49K 
                (Details)                                                        
59: R48         Debt - Private Placement Facilities - Narrative 2   HTML     24K 
                (Details)                                                        
60: R49         Debt - U.S. Trade Accounts Receivable               HTML     48K 
                Securitization - Narrative (Details)                             
61: R50         Debt - Private Placement Borrowings (Details)       HTML     73K 
62: R51         Leases - Narrative (Details)                        HTML     42K 
63: R52         Leases - Components of lease expense (Details)      HTML     34K 
64: R53         Leases - Supplemental balance sheet information     HTML     56K 
                (Details)                                                        
65: R54         Leases - Supplemental cash flow information         HTML     36K 
                (Details)                                                        
66: R55         Leases - Maturities of lease liabilities (Details)  HTML     64K 
67: R56         Leases - Present value of lease liabilities         HTML     37K 
                (Details)                                                        
68: R57         Redeemable Noncontrolling Interests (Details)       HTML     39K 
69: R58         Comprehensive Income - Accumulated Other            HTML     97K 
                Comprehensive Income and Comprehensive Income                    
                Components (Details)                                             
70: R59         Comprehensive Income - Total Comprehensive Income   HTML     35K 
                (Details)                                                        
71: R60         Fair Value Measurements (Details)                   HTML     78K 
72: R61         Business Acquisitions - Narrative (Details)         HTML     33K 
73: R62         Business Acquisitions - Acquisition consideration   HTML     57K 
                (Details)                                                        
74: R63         Plans of Restructuring - Narrative (Details)        HTML     26K 
75: R64         Plans of Restructuring - Restructuring Reserve      HTML     48K 
                Roll Forward by Expense and Segment (Details)                    
76: R65         Earnings Per Share (Details)                        HTML     33K 
77: R66         Income Taxes - Narrative (Details)                  HTML     41K 
78: R67         Derivatives and Hedging Activities - Narrative      HTML     68K 
                (Details)                                                        
79: R68         Stock-Based Compensation - Narrative (Details)      HTML     58K 
80: R69         Stock-Based Compensation - Black-Scholes valuation  HTML     33K 
                model (Details)                                                  
81: R70         Stock-Based Compensation - Summary of stock option  HTML     44K 
                activity (Details)                                               
82: R71         Stock-Based Compensation - Unvested Resticted       HTML     57K 
                Stock/Units Activity (Details)                                   
83: R72         Supplemental Cash Flow Information (Details)        HTML     31K 
84: R73         Legal Proceedings - Narrative (Details)             HTML     85K 
85: R74         Related Party Transactions - Narrative (Details)    HTML     61K 
87: XML         IDEA XML File -- Filing Summary                      XML    160K 
11: XML         XBRL Instance -- hsicform10q20210327_htm             XML   1.72M 
86: EXCEL       IDEA Workbook of Financial Reports                  XLSX    105K 
 7: EX-101.CAL  Inline XBRL Taxonomy Extension Calculation           XML    368K 
                Linkbase -- hsic-20210327_cal                                    
 8: EX-101.DEF  Inline XBRL Taxonomy Extension Definition Linkbase   XML    904K 
                -- hsic-20210327_def                                             
 9: EX-101.LAB  Inline XBRL Taxonomy Extension Label Linkbase --     XML   2.24M 
                hsic-20210327_lab                                                
10: EX-101.PRE  Inline XBRL Taxonomy Extension Presentation          XML   1.55M 
                Linkbase -- hsic-20210327_pre                                    
 6: EX-101.SCH  Inline XBRL Taxonomy Extension Schema --             XSD    185K 
                hsic-20210327                                                    
88: JSON        XBRL Instance as JSON Data -- MetaLinks              520±   768K 
89: ZIP         XBRL Zipped Folder -- 0001000228-21-000036-xbrl      Zip    333K 


‘EX-101.PRE’   —   Inline XBRL Taxonomy Extension Presentation Linkbase — hsic-20210327_pre


This Exhibit is an XBRL XML File.


                                                                                                                                                                                
<?xml version="1.0" encoding="windows-1252"?>
<!-- XBRL document created by Certent CDM version: 20.11.1 using Fujitsu Interstage XWand -->
<linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/instance http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd" xmlns="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xlink="http://www.w3.org/1999/xlink">
<roleRef roleURI="http://henryschein.com/role/BasisOfPresentation" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_BasisOfPresentation"/>
<roleRef roleURI="http://henryschein.com/role/BasisOfPresentationNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_BasisOfPresentationNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/BusinessAcquisitions" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureBusinessAcquisitions"/>
<roleRef roleURI="http://henryschein.com/role/BusinessAcquisitionsAcquisitionConsiderationDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_BusinessAcquisitionsAcquisitionConsiderationDetails"/>
<roleRef roleURI="http://henryschein.com/role/BusinessAcquisitionsNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_BusinessAcquisitionsNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/BusinessAcquisitionsTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_BusinessAcquisitionsTables"/>
<roleRef roleURI="http://henryschein.com/role/ComprehensiveIncome" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_ComprehensiveIncome"/>
<roleRef roleURI="http://henryschein.com/role/ComprehensiveIncomeAccumulatedOtherComprehensiveIncomeAndComprehensiveIncomeComponentsDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_ComprehensiveIncomeAccumulatedOtherComprehensiveIncomeAndComprehensiveIncomeComponentsDetails"/>
<roleRef roleURI="http://henryschein.com/role/ComprehensiveIncomeTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_ComprehensiveIncomeTables"/>
<roleRef roleURI="http://henryschein.com/role/ComprehensiveIncomeTotalComprehensiveIncomeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_ComprehensiveIncomeTotalComprehensiveIncomeDetails"/>
<roleRef roleURI="http://henryschein.com/role/CONSOLIDATEDBALANCESHEETSunaudited" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CONSOLIDATEDBALANCESHEETSunaudited"/>
<roleRef roleURI="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWSunaudited" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CONSOLIDATEDSTATEMENTSOFCASHFLOWSunaudited"/>
<roleRef roleURI="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCHANGESINSTOCKHOLDERSEQUITYunaudited" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CONSOLIDATEDSTATEMENTSOFCHANGESINSTOCKHOLDERSEQUITYunaudited"/>
<roleRef roleURI="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCHANGESINSTOCKHOLDERSEQUITYunauditedParenthetical" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CONSOLIDATEDSTATEMENTSOFCHANGESINSTOCKHOLDERSEQUITYunauditedParenthetical"/>
<roleRef roleURI="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOMEunaudited" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOMEunaudited"/>
<roleRef roleURI="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFINCOMEunaudited" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CONSOLIDATEDSTATEMENTSOFINCOMEunaudited"/>
<roleRef roleURI="http://henryschein.com/role/CoverPage" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CoverPage"/>
<roleRef roleURI="http://henryschein.com/role/CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandards" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandards"/>
<roleRef roleURI="http://henryschein.com/role/CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandardsNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandardsNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandardsPolicies" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandardsPolicies"/>
<roleRef roleURI="http://henryschein.com/role/Debt" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_Debt"/>
<roleRef roleURI="http://henryschein.com/role/DebtBankCreditLinesDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DebtBankCreditLinesDetails"/>
<roleRef roleURI="http://henryschein.com/role/DebtLongtermDebtDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DebtLongtermDebtDetails"/>
<roleRef roleURI="http://henryschein.com/role/DebtPrivatePlacementBorrowingsDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DebtPrivatePlacementBorrowingsDetails"/>
<roleRef roleURI="http://henryschein.com/role/DebtPrivatePlacementFacilitiesNarrative2Details" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DebtPrivatePlacementFacilitiesNarrative2Details"/>
<roleRef roleURI="http://henryschein.com/role/DebtPrivatePlacementFacilitiesNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DebtPrivatePlacementFacilitiesNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/DebtRevolvingCreditAgreement364DayCreditAgreementAndOtherShortTermCreditLinesNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DebtRevolvingCreditAgreement364DayCreditAgreementAndOtherShortTermCreditLinesNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/DebtTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureDebtTables"/>
<roleRef roleURI="http://henryschein.com/role/DebtUSTradeAccountsReceivableSecuritizationNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DebtUSTradeAccountsReceivableSecuritizationNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/DerivativesAndHedgingActivities" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DerivativesAndHedgingActivities"/>
<roleRef roleURI="http://henryschein.com/role/DerivativesAndHedgingActivitiesNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DerivativesAndHedgingActivitiesNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/DiscontinuedOperationsNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DiscontinuedOperationsNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/DiscontinuedOperationsSummarizedFinancialInformationForOurDiscontinuedOperationsDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DiscontinuedOperationsSummarizedFinancialInformationForOurDiscontinuedOperationsDetails"/>
<roleRef roleURI="http://henryschein.com/role/DiscontinuedOperationsTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DiscontinuedOperationsTables"/>
<roleRef roleURI="http://henryschein.com/role/EarningsPerShare" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureEarningsPerShare"/>
<roleRef roleURI="http://henryschein.com/role/EarningsPerShareDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_EarningsPerShareDetails"/>
<roleRef roleURI="http://henryschein.com/role/EarningsPerShareTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureEarningsPerShareTables"/>
<roleRef roleURI="http://henryschein.com/role/FairValueMeasurements" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureFairValueMeasurements"/>
<roleRef roleURI="http://henryschein.com/role/FairValueMeasurementsDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_FairValueMeasurementsDetails"/>
<roleRef roleURI="http://henryschein.com/role/FairValueMeasurementsTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_FairValueMeasurementsTables"/>
<roleRef roleURI="http://henryschein.com/role/IncomeTaxes" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_IncomeTaxes"/>
<roleRef roleURI="http://henryschein.com/role/IncomeTaxesNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_IncomeTaxesNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/Leases" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_Leases"/>
<roleRef roleURI="http://henryschein.com/role/LeasesComponentsOfLeaseExpenseDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LeasesComponentsOfLeaseExpenseDetails"/>
<roleRef roleURI="http://henryschein.com/role/LeasesMaturitiesOfLeaseLiabilitiesDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LeasesMaturitiesOfLeaseLiabilitiesDetails"/>
<roleRef roleURI="http://henryschein.com/role/LeasesNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LeasesNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/LeasesPresentValueOfLeaseLiabilitiesDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LeasesPresentValueOfLeaseLiabilitiesDetails"/>
<roleRef roleURI="http://henryschein.com/role/LeasesSupplementalBalanceSheetInformationDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LeasesSupplementalBalanceSheetInformationDetails"/>
<roleRef roleURI="http://henryschein.com/role/LeasesSupplementalCashFlowInformationDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LeasesSupplementalCashFlowInformationDetails"/>
<roleRef roleURI="http://henryschein.com/role/LeasesTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LeasesTables"/>
<roleRef roleURI="http://henryschein.com/role/LegalProceedings" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureLegalProceedings"/>
<roleRef roleURI="http://henryschein.com/role/LegalProceedingsNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_LegalProceedingsNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/PlansOfRestructuring" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_PlansOfRestructuring"/>
<roleRef roleURI="http://henryschein.com/role/PlansOfRestructuringNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_PlansOfRestructuringNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/PlansOfRestructuringRestructuringReserveRollForwardByExpenseAndSegmentDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_PlansOfRestructuringRestructuringReserveRollForwardByExpenseAndSegmentDetails"/>
<roleRef roleURI="http://henryschein.com/role/PlansOfRestructuringTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_PlansOfRestructuringTables"/>
<roleRef roleURI="http://henryschein.com/role/RedeemableNoncontrollingInterests" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureRedeemableNoncontrollingInterests"/>
<roleRef roleURI="http://henryschein.com/role/RedeemableNoncontrollingInterestsDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_RedeemableNoncontrollingInterestsDetails"/>
<roleRef roleURI="http://henryschein.com/role/RedeemableNoncontrollingInterestsTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureRedeemableNoncontrollingInterestsTables"/>
<roleRef roleURI="http://henryschein.com/role/RelatedPartyTransactions" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_RelatedPartyTransactions"/>
<roleRef roleURI="http://henryschein.com/role/RelatedPartyTransactionsNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_RelatedPartyTransactionsNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/RevenueFromContractsWithCustomers" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureRevenueFromContractsWithCustomers"/>
<roleRef roleURI="http://henryschein.com/role/RevenueFromContractsWithCustomersContractBalancesDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureRevenueFromContractsWithCustomersContractBalancesDetails"/>
<roleRef roleURI="http://henryschein.com/role/RevenueFromContractsWithCustomersDisaggregationOfRevenueDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureRevenueFromContractsWithCustomersDisaggregationOfRevenueDetails"/>
<roleRef roleURI="http://henryschein.com/role/RevenueFromContractsWithCustomersTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureRevenueFromContractsWithCustomersTables"/>
<roleRef roleURI="http://henryschein.com/role/SegmentData" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureSegmentData"/>
<roleRef roleURI="http://henryschein.com/role/SegmentDataDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_SegmentDataDetails"/>
<roleRef roleURI="http://henryschein.com/role/SegmentDataTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureSegmentDataTables"/>
<roleRef roleURI="http://henryschein.com/role/StatementCONSOLIDATEDBALANCESHEETSParenthetical" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_StatementCONSOLIDATEDBALANCESHEETSParenthetical"/>
<roleRef roleURI="http://henryschein.com/role/StockBasedCompensation" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_DisclosureStockBasedCompensation"/>
<roleRef roleURI="http://henryschein.com/role/StockBasedCompensationBlackScholesValuationModelDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_StockBasedCompensationBlackScholesValuationModelDetails"/>
<roleRef roleURI="http://henryschein.com/role/StockBasedCompensationNarrativeDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_StockBasedCompensationNarrativeDetails"/>
<roleRef roleURI="http://henryschein.com/role/StockBasedCompensationSummaryOfStockOptionActivityDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_StockBasedCompensationSummaryOfStockOptionActivityDetails"/>
<roleRef roleURI="http://henryschein.com/role/StockBasedCompensationTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_StockBasedCompensationTables"/>
<roleRef roleURI="http://henryschein.com/role/StockBasedCompensationUnvestedRestictedStockUnitsActivityDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_StockBasedCompensationUnvestedRestictedStockUnitsActivityDetails"/>
<roleRef roleURI="http://henryschein.com/role/SupplementalCashFlowInformation" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_SupplementalCashFlowInformation"/>
<roleRef roleURI="http://henryschein.com/role/SupplementalCashFlowInformationDetails" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_SupplementalCashFlowInformationDetails"/>
<roleRef roleURI="http://henryschein.com/role/SupplementalCashFlowInformationTables" xlink:type="simple" xlink:href="hsic-20210327.xsd#ELRID_SupplementalCashFlowInformationTables"/>
<roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel"/>
<roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel"/>
<roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel"/>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CONSOLIDATEDBALANCESHEETSunaudited">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_1"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_2"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_1" xlink:to="Locator_us-gaap_AssetsCurrentAbstract_2" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_15"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_16"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsCurrentAbstract_15" xlink:to="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_16" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_17"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="Locator_us-gaap_AccountsReceivableNetCurrent_18"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsCurrentAbstract_17" xlink:to="Locator_us-gaap_AccountsReceivableNetCurrent_18" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_19"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InventoryNet" xlink:label="Locator_us-gaap_InventoryNet_20"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsCurrentAbstract_19" xlink:to="Locator_us-gaap_InventoryNet_20" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_21"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="Locator_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_22"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsCurrentAbstract_21" xlink:to="Locator_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_22" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_23"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="Locator_us-gaap_AssetsCurrent_24"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsCurrentAbstract_23" xlink:to="Locator_us-gaap_AssetsCurrent_24" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_3"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization" xlink:label="Locator_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_4"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_3" xlink:to="Locator_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_4" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_5"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="Locator_us-gaap_OperatingLeaseRightOfUseAsset_6"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_5" xlink:to="Locator_us-gaap_OperatingLeaseRightOfUseAsset_6" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_7"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill" xlink:label="Locator_us-gaap_Goodwill_8"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_7" xlink:to="Locator_us-gaap_Goodwill_8" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_9"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="Locator_us-gaap_IntangibleAssetsNetExcludingGoodwill_10"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_9" xlink:to="Locator_us-gaap_IntangibleAssetsNetExcludingGoodwill_10" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_11"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsAndOtherNoncurrentAssets" xlink:label="Locator_us-gaap_InvestmentsAndOtherNoncurrentAssets_12"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_11" xlink:to="Locator_us-gaap_InvestmentsAndOtherNoncurrentAssets_12" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_13"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets" xlink:label="Locator_us-gaap_Assets_14"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_13" xlink:to="Locator_us-gaap_Assets_14" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="Locator_us-gaap_StatementOfFinancialPositionAbstract_25"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_26"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfFinancialPositionAbstract_25" xlink:to="Locator_us-gaap_AssetsAbstract_26" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="Locator_us-gaap_StatementOfFinancialPositionAbstract_27"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_28"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfFinancialPositionAbstract_27" xlink:to="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_28" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_29"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_LiabilitiesCurrentAbstract_30"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_29" xlink:to="Locator_us-gaap_LiabilitiesCurrentAbstract_30" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_LiabilitiesCurrentAbstract_49"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsPayableCurrent" xlink:label="Locator_us-gaap_AccountsPayableCurrent_50"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesCurrentAbstract_49" xlink:to="Locator_us-gaap_AccountsPayableCurrent_50" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_LiabilitiesCurrentAbstract_51"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermBorrowings" xlink:label="Locator_us-gaap_ShortTermBorrowings_52"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesCurrentAbstract_51" xlink:to="Locator_us-gaap_ShortTermBorrowings_52" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_LiabilitiesCurrentAbstract_53"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligationsCurrent" xlink:label="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligationsCurrent_54"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesCurrentAbstract_53" xlink:to="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligationsCurrent_54" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_LiabilitiesCurrentAbstract_55"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="Locator_us-gaap_OperatingLeaseLiabilityCurrent_56"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesCurrentAbstract_55" xlink:to="Locator_us-gaap_OperatingLeaseLiabilityCurrent_56" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_LiabilitiesCurrentAbstract_57"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_58"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesCurrentAbstract_57" xlink:to="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_58" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_61"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent" xlink:label="Locator_us-gaap_EmployeeRelatedLiabilitiesCurrent_62"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_61" xlink:to="Locator_us-gaap_EmployeeRelatedLiabilitiesCurrent_62" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_63"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxesPayableCurrent" xlink:label="Locator_us-gaap_TaxesPayableCurrent_64"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_63" xlink:to="Locator_us-gaap_TaxesPayableCurrent_64" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_65"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherLiabilitiesCurrent" xlink:label="Locator_us-gaap_OtherLiabilitiesCurrent_66"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AccruedLiabilitiesCurrentAbstract_65" xlink:to="Locator_us-gaap_OtherLiabilitiesCurrent_66" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_LiabilitiesCurrentAbstract_59"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="Locator_us-gaap_LiabilitiesCurrent_60"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesCurrentAbstract_59" xlink:to="Locator_us-gaap_LiabilitiesCurrent_60" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_31"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligations" xlink:label="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligations_32"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_31" xlink:to="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligations_32" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_33"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet" xlink:label="Locator_us-gaap_DeferredIncomeTaxLiabilitiesNet_34"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_33" xlink:to="Locator_us-gaap_DeferredIncomeTaxLiabilitiesNet_34" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_35"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="Locator_us-gaap_OperatingLeaseLiabilityNoncurrent_36"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_35" xlink:to="Locator_us-gaap_OperatingLeaseLiabilityNoncurrent_36" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_37"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent" xlink:label="Locator_us-gaap_OtherLiabilitiesNoncurrent_38"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_37" xlink:to="Locator_us-gaap_OtherLiabilitiesNoncurrent_38" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_39"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Liabilities" xlink:label="Locator_us-gaap_Liabilities_40"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_39" xlink:to="Locator_us-gaap_Liabilities_40" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_41"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests" xlink:label="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_42"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_41" xlink:to="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_42" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_43"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="Locator_us-gaap_CommitmentsAndContingencies_44"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_43" xlink:to="Locator_us-gaap_CommitmentsAndContingencies_44" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_45"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_46"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_45" xlink:to="Locator_us-gaap_StockholdersEquityAbstract_46" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_67"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockValueOutstanding" xlink:label="Locator_us-gaap_PreferredStockValueOutstanding_68"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_67" xlink:to="Locator_us-gaap_PreferredStockValueOutstanding_68" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_69"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockValueOutstanding" xlink:label="Locator_us-gaap_CommonStockValueOutstanding_70"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_69" xlink:to="Locator_us-gaap_CommonStockValueOutstanding_70" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_71"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="Locator_us-gaap_AdditionalPaidInCapital_72"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_71" xlink:to="Locator_us-gaap_AdditionalPaidInCapital_72" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_73"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="Locator_us-gaap_RetainedEarningsAccumulatedDeficit_74"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_73" xlink:to="Locator_us-gaap_RetainedEarningsAccumulatedDeficit_74" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_75"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_76"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_75" xlink:to="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_76" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_77"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="Locator_us-gaap_StockholdersEquity_78"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_77" xlink:to="Locator_us-gaap_StockholdersEquity_78" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_79"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MinorityInterest" xlink:label="Locator_us-gaap_MinorityInterest_80"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_79" xlink:to="Locator_us-gaap_MinorityInterest_80" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_81"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_82"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_81" xlink:to="Locator_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_82" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_47"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="Locator_us-gaap_LiabilitiesAndStockholdersEquity_48"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract_47" xlink:to="Locator_us-gaap_LiabilitiesAndStockholdersEquity_48" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFINCOMEunaudited">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_147"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_148"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_147" xlink:to="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_148" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_149"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold" xlink:label="Locator_us-gaap_CostOfGoodsAndServicesSold_150"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_149" xlink:to="Locator_us-gaap_CostOfGoodsAndServicesSold_150" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_151"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GrossProfit" xlink:label="Locator_us-gaap_GrossProfit_152"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_151" xlink:to="Locator_us-gaap_GrossProfit_152" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_153"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="Locator_us-gaap_OperatingExpensesAbstract_154"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_153" xlink:to="Locator_us-gaap_OperatingExpensesAbstract_154" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="Locator_us-gaap_OperatingExpensesAbstract_187"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense" xlink:label="Locator_us-gaap_SellingGeneralAndAdministrativeExpense_188"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingExpensesAbstract_187" xlink:to="Locator_us-gaap_SellingGeneralAndAdministrativeExpense_188" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="Locator_us-gaap_OperatingExpensesAbstract_189"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringSettlementAndImpairmentProvisions" xlink:label="Locator_us-gaap_RestructuringSettlementAndImpairmentProvisions_190"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingExpensesAbstract_189" xlink:to="Locator_us-gaap_RestructuringSettlementAndImpairmentProvisions_190" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_155"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="Locator_us-gaap_OperatingIncomeLoss_156"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_155" xlink:to="Locator_us-gaap_OperatingIncomeLoss_156" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_157"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_158"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_157" xlink:to="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_158" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_191"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentIncomeInterest" xlink:label="Locator_us-gaap_InvestmentIncomeInterest_192"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_191" xlink:to="Locator_us-gaap_InvestmentIncomeInterest_192" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_193"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpense" xlink:label="Locator_us-gaap_InterestExpense_194"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_193" xlink:to="Locator_us-gaap_InterestExpense_194" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_195"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="Locator_us-gaap_OtherNonoperatingIncomeExpense_196"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NonoperatingIncomeExpenseAbstract_195" xlink:to="Locator_us-gaap_OtherNonoperatingIncomeExpense_196" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_159"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="Locator_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_160"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_159" xlink:to="Locator_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_160" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_161"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="Locator_us-gaap_IncomeTaxExpenseBenefit_162"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_161" xlink:to="Locator_us-gaap_IncomeTaxExpenseBenefit_162" order="8.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_163"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments" xlink:label="Locator_us-gaap_IncomeLossFromEquityMethodInvestments_164"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_163" xlink:to="Locator_us-gaap_IncomeLossFromEquityMethodInvestments_164" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_165"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_166"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_165" xlink:to="Locator_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_166" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_167"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax" xlink:label="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_168"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_167" xlink:to="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_168" order="11.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_169"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProfitLoss" xlink:label="Locator_us-gaap_ProfitLoss_170"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_169" xlink:to="Locator_us-gaap_ProfitLoss_170" order="12.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_171"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsAttributableToNoncontrollingEntity" xlink:label="Locator_us-gaap_IncomeLossFromContinuingOperationsAttributableToNoncontrollingEntity_172"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_171" xlink:to="Locator_us-gaap_IncomeLossFromContinuingOperationsAttributableToNoncontrollingEntity_172" order="13.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_175"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperations" xlink:label="Locator_us-gaap_IncomeLossFromContinuingOperations_176"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_175" xlink:to="Locator_us-gaap_IncomeLossFromContinuingOperations_176" order="15.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_177"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_178"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_177" xlink:to="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_178" order="16.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_173"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="Locator_us-gaap_NetIncomeLoss_174"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_173" xlink:to="Locator_us-gaap_NetIncomeLoss_174" order="14.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_179"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="Locator_us-gaap_NetIncomeLoss_180"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_179" xlink:to="Locator_us-gaap_NetIncomeLoss_180" order="17.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_181"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedAbstract" xlink:label="Locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract_182"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_181" xlink:to="Locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract_182" order="18.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedAbstract" xlink:label="Locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract_197"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="Locator_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_198"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract_197" xlink:to="Locator_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_198" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedAbstract" xlink:label="Locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract_199"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare" xlink:label="Locator_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_200"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract_199" xlink:to="Locator_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_200" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_183"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract" xlink:label="Locator_us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract_184"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_183" xlink:to="Locator_us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract_184" order="19.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract" xlink:label="Locator_us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract_201"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare" xlink:label="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare_202"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract_201" xlink:to="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare_202" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract" xlink:label="Locator_us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract_203"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare" xlink:label="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare_204"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareBasicAndDilutedOtherDisclosuresAbstract_203" xlink:to="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare_204" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_185"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="Locator_us-gaap_EarningsPerShareAbstract_186"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_185" xlink:to="Locator_us-gaap_EarningsPerShareAbstract_186" order="20.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="Locator_us-gaap_EarningsPerShareAbstract_205"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="Locator_us-gaap_EarningsPerShareBasic_206"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareAbstract_205" xlink:to="Locator_us-gaap_EarningsPerShareBasic_206" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="Locator_us-gaap_EarningsPerShareAbstract_207"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="Locator_us-gaap_EarningsPerShareDiluted_208"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareAbstract_207" xlink:to="Locator_us-gaap_EarningsPerShareDiluted_208" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="Locator_us-gaap_EarningsPerShareAbstract_209"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_210"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareAbstract_209" xlink:to="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_210" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_211"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_212"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_211" xlink:to="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_212" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_213"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="Locator_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_214"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_213" xlink:to="Locator_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_214" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWSunaudited">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_251"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_252"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_251" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_252" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_271"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProfitLoss" xlink:label="Locator_us-gaap_ProfitLoss_272"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_271" xlink:to="Locator_us-gaap_ProfitLoss_272" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_273"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax" xlink:label="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_274"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_273" xlink:to="Locator_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_274" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_275"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_276"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_275" xlink:to="Locator_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_276" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_277"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_278"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_277" xlink:to="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_278" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_285"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="Locator_us-gaap_DepreciationDepletionAndAmortization_286"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_285" xlink:to="Locator_us-gaap_DepreciationDepletionAndAmortization_286" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_287"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="Locator_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_288"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_287" xlink:to="Locator_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_288" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_289"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="Locator_us-gaap_ShareBasedCompensation_290"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_289" xlink:to="Locator_us-gaap_ShareBasedCompensation_290" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_291"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForDoubtfulAccounts" xlink:label="Locator_us-gaap_ProvisionForDoubtfulAccounts_292"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_291" xlink:to="Locator_us-gaap_ProvisionForDoubtfulAccounts_292" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_293"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="Locator_us-gaap_DeferredIncomeTaxExpenseBenefit_294"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_293" xlink:to="Locator_us-gaap_DeferredIncomeTaxExpenseBenefit_294" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_295"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments" xlink:label="Locator_us-gaap_IncomeLossFromEquityMethodInvestments_296"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_295" xlink:to="Locator_us-gaap_IncomeLossFromEquityMethodInvestments_296" order="6.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_297"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityMethodInvestmentDividendsOrDistributions" xlink:label="Locator_us-gaap_EquityMethodInvestmentDividendsOrDistributions_298"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_297" xlink:to="Locator_us-gaap_EquityMethodInvestmentDividendsOrDistributions_298" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_299"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentForChangesInUnrecognizedTaxBenefits" xlink:label="Locator_hsic_AdjustmentForChangesInUnrecognizedTaxBenefits_300"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_299" xlink:to="Locator_hsic_AdjustmentForChangesInUnrecognizedTaxBenefits_300" order="8.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_301"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNoncashIncomeExpense" xlink:label="Locator_us-gaap_OtherNoncashIncomeExpense_302"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_301" xlink:to="Locator_us-gaap_OtherNoncashIncomeExpense_302" order="9.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_303"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_304"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_303" xlink:to="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_304" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_305"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="Locator_us-gaap_IncreaseDecreaseInAccountsReceivable_306"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_305" xlink:to="Locator_us-gaap_IncreaseDecreaseInAccountsReceivable_306" order="1.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_307"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="Locator_us-gaap_IncreaseDecreaseInInventories_308"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_307" xlink:to="Locator_us-gaap_IncreaseDecreaseInInventories_308" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_309"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherCurrentAssets" xlink:label="Locator_us-gaap_IncreaseDecreaseInOtherCurrentAssets_310"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_309" xlink:to="Locator_us-gaap_IncreaseDecreaseInOtherCurrentAssets_310" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_311"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="Locator_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_312"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_311" xlink:to="Locator_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_312" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_279"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_280"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_279" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_280" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_281"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations" xlink:label="Locator_us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations_282"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_281" xlink:to="Locator_us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations_282" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_283"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivities_284"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_283" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInOperatingActivities_284" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_253"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_254"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_253" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_254" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_313"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireProductiveAssets" xlink:label="Locator_us-gaap_PaymentsToAcquireProductiveAssets_314"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_313" xlink:to="Locator_us-gaap_PaymentsToAcquireProductiveAssets_314" order="1.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_315"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates" xlink:label="Locator_us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates_316"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_315" xlink:to="Locator_us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates_316" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_317"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfEquityMethodInvestments" xlink:label="Locator_us-gaap_ProceedsFromSaleOfEquityMethodInvestments_318"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_317" xlink:to="Locator_us-gaap_ProceedsFromSaleOfEquityMethodInvestments_318" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_319"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromPaymentsForLongTermLoansForRelatedParties" xlink:label="Locator_us-gaap_ProceedsFromPaymentsForLongTermLoansForRelatedParties_320"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_319" xlink:to="Locator_us-gaap_ProceedsFromPaymentsForLongTermLoansForRelatedParties_320" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_321"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:label="Locator_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_322"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_321" xlink:to="Locator_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_322" order="5.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_323"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations_324"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_323" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations_324" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_325"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations" xlink:label="Locator_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_326"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_325" xlink:to="Locator_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_326" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_327"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivities_328"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_327" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInInvestingActivities_328" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_255"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_256"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_255" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_256" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_329"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromRepaymentsOfLinesOfCredit" xlink:label="Locator_us-gaap_ProceedsFromRepaymentsOfLinesOfCredit_330"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_329" xlink:to="Locator_us-gaap_ProceedsFromRepaymentsOfLinesOfCredit_330" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_331"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:label="Locator_us-gaap_ProceedsFromIssuanceOfLongTermDebt_332"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_331" xlink:to="Locator_us-gaap_ProceedsFromIssuanceOfLongTermDebt_332" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_333"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="Locator_us-gaap_RepaymentsOfLongTermDebt_334"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_333" xlink:to="Locator_us-gaap_RepaymentsOfLongTermDebt_334" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_335"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfDebtIssuanceCosts" xlink:label="Locator_us-gaap_PaymentsOfDebtIssuanceCosts_336"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_335" xlink:to="Locator_us-gaap_PaymentsOfDebtIssuanceCosts_336" order="4.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_337"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfDebtExtinguishmentCosts" xlink:label="Locator_us-gaap_PaymentsOfDebtExtinguishmentCosts_338"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_337" xlink:to="Locator_us-gaap_PaymentsOfDebtExtinguishmentCosts_338" order="5.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_339"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="Locator_us-gaap_ProceedsFromStockOptionsExercised_340"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_339" xlink:to="Locator_us-gaap_ProceedsFromStockOptionsExercised_340" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_341"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:label="Locator_us-gaap_PaymentsForRepurchaseOfCommonStock_342"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_341" xlink:to="Locator_us-gaap_PaymentsForRepurchaseOfCommonStock_342" order="7.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_343"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:label="Locator_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_344"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_343" xlink:to="Locator_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_344" order="8.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_345"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfInterestInCorporateUnit" xlink:label="Locator_us-gaap_ProceedsFromSaleOfInterestInCorporateUnit_346"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_345" xlink:to="Locator_us-gaap_ProceedsFromSaleOfInterestInCorporateUnit_346" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_347"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromContributionsFromAffiliates" xlink:label="Locator_us-gaap_ProceedsFromContributionsFromAffiliates_348"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_347" xlink:to="Locator_us-gaap_ProceedsFromContributionsFromAffiliates_348" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_349"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromPaymentsToMinorityShareholders" xlink:label="Locator_us-gaap_ProceedsFromPaymentsToMinorityShareholders_350"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_349" xlink:to="Locator_us-gaap_ProceedsFromPaymentsToMinorityShareholders_350" order="11.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_351"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PaymentsToNoncontrollingInterestsAndPaymentsForRepurchaseOfRedeemableNoncontrollingInterest" xlink:label="Locator_hsic_PaymentsToNoncontrollingInterestsAndPaymentsForRepurchaseOfRedeemableNoncontrollingInterest_352"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_351" xlink:to="Locator_hsic_PaymentsToNoncontrollingInterestsAndPaymentsForRepurchaseOfRedeemableNoncontrollingInterest_352" order="12.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_353"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ProceedsFromPaymentsToAffiliates" xlink:label="Locator_hsic_ProceedsFromPaymentsToAffiliates_354"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_353" xlink:to="Locator_hsic_ProceedsFromPaymentsToAffiliates_354" order="13.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_355"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations_356"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_355" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations_356" order="14.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_357"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashProvidedByUsedInFinancingActivitiesDiscontinuedOperations" xlink:label="Locator_us-gaap_CashProvidedByUsedInFinancingActivitiesDiscontinuedOperations_358"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_357" xlink:to="Locator_us-gaap_CashProvidedByUsedInFinancingActivitiesDiscontinuedOperations_358" order="15.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_359"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivities_360"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_359" xlink:to="Locator_us-gaap_NetCashProvidedByUsedInFinancingActivities_360" order="16.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_257"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="Locator_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_258"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_257" xlink:to="Locator_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_258" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_259"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsDisposalGroupIncludingDiscontinuedOperations" xlink:label="Locator_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsDisposalGroupIncludingDiscontinuedOperations_260"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_259" xlink:to="Locator_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsDisposalGroupIncludingDiscontinuedOperations_260" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_261"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffectContiuningOperations" xlink:label="Locator_hsic_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffectContiuningOperations_262"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_261" xlink:to="Locator_hsic_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffectContiuningOperations_262" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_263"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffectDisposalGroupAndDiscontinuedOperations" xlink:label="Locator_hsic_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffectDisposalGroupAndDiscontinuedOperations_264"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_263" xlink:to="Locator_hsic_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffectDisposalGroupAndDiscontinuedOperations_264" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_265"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:label="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_266"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_265" xlink:to="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_266" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_267"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_268"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_267" xlink:to="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_268" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="Locator_us-gaap_StatementOfCashFlowsAbstract_269"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_270"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfCashFlowsAbstract_269" xlink:to="Locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_270" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/BasisOfPresentation">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="Locator_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_463"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:label="Locator_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_464"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_463" xlink:to="Locator_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_464" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/SegmentData">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="Locator_us-gaap_SegmentReportingAbstract_465"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingDisclosureTextBlock" xlink:label="Locator_us-gaap_SegmentReportingDisclosureTextBlock_466"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentReportingAbstract_465" xlink:to="Locator_us-gaap_SegmentReportingDisclosureTextBlock_466" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/StockBasedCompensation">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_467"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_468"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_467" xlink:to="Locator_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_468" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/BusinessAcquisitions">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationsAbstract_469"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock" xlink:label="Locator_us-gaap_BusinessCombinationDisclosureTextBlock_470"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationsAbstract_469" xlink:to="Locator_us-gaap_BusinessCombinationDisclosureTextBlock_470" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/EarningsPerShare">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="Locator_us-gaap_EarningsPerShareAbstract_471"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="Locator_us-gaap_EarningsPerShareTextBlock_472"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareAbstract_471" xlink:to="Locator_us-gaap_EarningsPerShareTextBlock_472" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/ComprehensiveIncome">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_473"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNoteTextBlock" xlink:label="Locator_us-gaap_ComprehensiveIncomeNoteTextBlock_474"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_473" xlink:to="Locator_us-gaap_ComprehensiveIncomeNoteTextBlock_474" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/FairValueMeasurements">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="Locator_us-gaap_FairValueDisclosuresAbstract_475"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementInputsDisclosureTextBlock" xlink:label="Locator_us-gaap_FairValueMeasurementInputsDisclosureTextBlock_476"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueDisclosuresAbstract_475" xlink:to="Locator_us-gaap_FairValueMeasurementInputsDisclosureTextBlock_476" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/IncomeTaxes">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_477"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="Locator_us-gaap_IncomeTaxDisclosureTextBlock_478"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_477" xlink:to="Locator_us-gaap_IncomeTaxDisclosureTextBlock_478" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/SupplementalCashFlowInformation">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowElementsAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowElementsAbstract_479"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashFlowSupplementalDisclosuresTextBlock" xlink:label="Locator_us-gaap_CashFlowSupplementalDisclosuresTextBlock_480"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowElementsAbstract_479" xlink:to="Locator_us-gaap_CashFlowSupplementalDisclosuresTextBlock_480" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/PlansOfRestructuring">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_481"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock" xlink:label="Locator_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_482"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_481" xlink:to="Locator_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_482" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DerivativesAndHedgingActivities">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="Locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_483"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:label="Locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_484"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_483" xlink:to="Locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_484" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/StatementCONSOLIDATEDBALANCESHEETSParenthetical">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_485"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent" xlink:label="Locator_us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_486"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsCurrentAbstract_485" xlink:to="Locator_us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_486" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_487"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="Locator_us-gaap_PreferredStockParOrStatedValuePerShare_488"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_487" xlink:to="Locator_us-gaap_PreferredStockParOrStatedValuePerShare_488" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_489"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="Locator_us-gaap_PreferredStockSharesAuthorized_490"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_489" xlink:to="Locator_us-gaap_PreferredStockSharesAuthorized_490" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_491"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="Locator_us-gaap_PreferredStockSharesOutstanding_492"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_491" xlink:to="Locator_us-gaap_PreferredStockSharesOutstanding_492" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_493"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="Locator_us-gaap_CommonStockParOrStatedValuePerShare_494"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_493" xlink:to="Locator_us-gaap_CommonStockParOrStatedValuePerShare_494" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_495"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="Locator_us-gaap_CommonStockSharesAuthorized_496"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_495" xlink:to="Locator_us-gaap_CommonStockSharesAuthorized_496" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_497"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="Locator_us-gaap_CommonStockSharesOutstanding_498"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StockholdersEquityAbstract_497" xlink:to="Locator_us-gaap_CommonStockSharesOutstanding_498" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="Locator_us-gaap_StatementOfFinancialPositionAbstract_499"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="Locator_us-gaap_AssetsCurrentAbstract_500"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfFinancialPositionAbstract_499" xlink:to="Locator_us-gaap_AssetsCurrentAbstract_500" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="Locator_us-gaap_StatementOfFinancialPositionAbstract_501"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="Locator_us-gaap_StockholdersEquityAbstract_502"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfFinancialPositionAbstract_501" xlink:to="Locator_us-gaap_StockholdersEquityAbstract_502" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCHANGESINSTOCKHOLDERSEQUITYunaudited">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="Locator_us-gaap_StatementEquityComponentsAxis_651"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="Locator_us-gaap_EquityComponentDomain_652"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementEquityComponentsAxis_651" xlink:to="Locator_us-gaap_EquityComponentDomain_652" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="Locator_us-gaap_EquityComponentDomain_655"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncontrollingInterestMember" xlink:label="Locator_us-gaap_NoncontrollingInterestMember_656"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EquityComponentDomain_655" xlink:to="Locator_us-gaap_NoncontrollingInterestMember_656" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="Locator_us-gaap_EquityComponentDomain_653"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember" xlink:label="Locator_us-gaap_ParentMember_654"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EquityComponentDomain_653" xlink:to="Locator_us-gaap_ParentMember_654" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember" xlink:label="Locator_us-gaap_ParentMember_657"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember" xlink:label="Locator_us-gaap_CommonStockMember_658"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ParentMember_657" xlink:to="Locator_us-gaap_CommonStockMember_658" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember" xlink:label="Locator_us-gaap_ParentMember_659"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="Locator_us-gaap_AdditionalPaidInCapitalMember_660"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ParentMember_659" xlink:to="Locator_us-gaap_AdditionalPaidInCapitalMember_660" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember" xlink:label="Locator_us-gaap_ParentMember_663"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeMember_664"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ParentMember_663" xlink:to="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeMember_664" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember" xlink:label="Locator_us-gaap_ParentMember_661"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="Locator_us-gaap_RetainedEarningsMember_662"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ParentMember_661" xlink:to="Locator_us-gaap_RetainedEarningsMember_662" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_665"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_666"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_665" xlink:to="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_666" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_667"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_668"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_667" xlink:to="Locator_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_668" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_647"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="Locator_us-gaap_StatementEquityComponentsAxis_648"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_647" xlink:to="Locator_us-gaap_StatementEquityComponentsAxis_648" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_649"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_650"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_649" xlink:to="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_650" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_645"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_646"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_645" xlink:to="Locator_us-gaap_StatementLineItems_646" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_507"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLossIncludingPortionAttributableToNonredeemableNoncontrollingInterest" xlink:label="Locator_us-gaap_NetIncomeLossIncludingPortionAttributableToNonredeemableNoncontrollingInterest_508"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_507" xlink:to="Locator_us-gaap_NetIncomeLossIncludingPortionAttributableToNonredeemableNoncontrollingInterest_508" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_509"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxExcludingPortionAttributableToRedeemableNoncontrollingInterest" xlink:label="Locator_hsic_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxExcludingPortionAttributableToRedeemableNoncontrollingInterest_510"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_509" xlink:to="Locator_hsic_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxExcludingPortionAttributableToRedeemableNoncontrollingInterest_510" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_511"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_512"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_511" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_512" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_513"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_514"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_513" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_514" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_515"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_516"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_515" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_516" order="7.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_517"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MinorityInterestDecreaseFromDistributionsToNoncontrollingInterestHolders" xlink:label="Locator_us-gaap_MinorityInterestDecreaseFromDistributionsToNoncontrollingInterestHolders_518"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_517" xlink:to="Locator_us-gaap_MinorityInterestDecreaseFromDistributionsToNoncontrollingInterestHolders_518" order="8.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_519"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityOther" xlink:label="Locator_us-gaap_StockholdersEquityOther_520"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_519" xlink:to="Locator_us-gaap_StockholdersEquityOther_520" order="9.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_521"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_MinorityInterestDecreaseFromPurchaseOfNoncontrollingInterests" xlink:label="Locator_hsic_MinorityInterestDecreaseFromPurchaseOfNoncontrollingInterests_522"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_521" xlink:to="Locator_hsic_MinorityInterestDecreaseFromPurchaseOfNoncontrollingInterests_522" order="10.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_523"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ChangesInFairValueOfRedeemableSecurities" xlink:label="Locator_hsic_ChangesInFairValueOfRedeemableSecurities_524"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_523" xlink:to="Locator_hsic_ChangesInFairValueOfRedeemableSecurities_524" order="11.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_525"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncontrollingInterestIncreaseFromBusinessCombination" xlink:label="Locator_us-gaap_NoncontrollingInterestIncreaseFromBusinessCombination_526"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_525" xlink:to="Locator_us-gaap_NoncontrollingInterestIncreaseFromBusinessCombination_526" order="12.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_527"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentToStockForSpinOffTransactionValue" xlink:label="Locator_hsic_AdjustmentToStockForSpinOffTransactionValue_528"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_527" xlink:to="Locator_hsic_AdjustmentToStockForSpinOffTransactionValue_528" order="13.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_529"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentToStockForSpinOffTransactionShares" xlink:label="Locator_hsic_AdjustmentToStockForSpinOffTransactionShares_530"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_529" xlink:to="Locator_hsic_AdjustmentToStockForSpinOffTransactionShares_530" order="14.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_531"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodValue" xlink:label="Locator_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_532"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_531" xlink:to="Locator_us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_532" order="15.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_533"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchasedAndRetiredDuringPeriodShares" xlink:label="Locator_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_534"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_533" xlink:to="Locator_us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_534" order="16.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_535"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xlink:label="Locator_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_536"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_535" xlink:to="Locator_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_536" order="17.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_537"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="Locator_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_538"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_537" xlink:to="Locator_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_538" order="18.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_539"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:label="Locator_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_540"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_539" xlink:to="Locator_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_540" order="19.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_541"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:label="Locator_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_542"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_541" xlink:to="Locator_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_542" order="20.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_543"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:label="Locator_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_544"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_543" xlink:to="Locator_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_544" order="21.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_545"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation" xlink:label="Locator_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation_546"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_545" xlink:to="Locator_us-gaap_SharesPaidForTaxWithholdingForShareBasedCompensation_546" order="22.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_547"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationOtherLongtermIncentivePlansSettledInCash" xlink:label="Locator_hsic_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationOtherLongtermIncentivePlansSettledInCash_548"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_547" xlink:to="Locator_hsic_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationOtherLongtermIncentivePlansSettledInCash_548" order="23.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_549"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationOtherLongtermIncentivePlansSettledInCashShares" xlink:label="Locator_hsic_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationOtherLongtermIncentivePlansSettledInCashShares_550"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_549" xlink:to="Locator_hsic_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationOtherLongtermIncentivePlansSettledInCashShares_550" order="24.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_551"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentToAdditionalPaidInCapitalSaleOfStockRelatedToSpinOffTransaction" xlink:label="Locator_hsic_AdjustmentToAdditionalPaidInCapitalSaleOfStockRelatedToSpinOffTransaction_552"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_551" xlink:to="Locator_hsic_AdjustmentToAdditionalPaidInCapitalSaleOfStockRelatedToSpinOffTransaction_552" order="25.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_553"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityNoteSpinoffTransaction" xlink:label="Locator_us-gaap_StockholdersEquityNoteSpinoffTransaction_554"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_553" xlink:to="Locator_us-gaap_StockholdersEquityNoteSpinoffTransaction_554" order="26.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_555"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ReclassificationOfAdditionalPaidInCapitalToRetainedEarnings" xlink:label="Locator_hsic_ReclassificationOfAdditionalPaidInCapitalToRetainedEarnings_556"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_555" xlink:to="Locator_hsic_ReclassificationOfAdditionalPaidInCapitalToRetainedEarnings_556" order="27.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_503"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_504"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_503" xlink:to="Locator_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_504" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_557"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_558"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_557" xlink:to="Locator_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_558" order="28.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_505"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="Locator_us-gaap_CommonStockSharesOutstanding_506"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_505" xlink:to="Locator_us-gaap_CommonStockSharesOutstanding_506" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_559"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="Locator_us-gaap_CommonStockSharesOutstanding_560"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_559" xlink:to="Locator_us-gaap_CommonStockSharesOutstanding_560" order="29.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="Locator_us-gaap_StatementOfStockholdersEquityAbstract_563"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_564"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfStockholdersEquityAbstract_563" xlink:to="Locator_us-gaap_StatementTable_564" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCHANGESINSTOCKHOLDERSEQUITYunauditedParenthetical">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOperatingActivitiesSegmentAxis" xlink:label="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_701"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="Locator_us-gaap_SegmentOperatingActivitiesDomain_702"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_701" xlink:to="Locator_us-gaap_SegmentOperatingActivitiesDomain_702" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="Locator_us-gaap_SegmentOperatingActivitiesDomain_705"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDiscontinuedOperationsMember" xlink:label="Locator_us-gaap_SegmentDiscontinuedOperationsMember_706"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentOperatingActivitiesDomain_705" xlink:to="Locator_us-gaap_SegmentDiscontinuedOperationsMember_706" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="Locator_us-gaap_SegmentOperatingActivitiesDomain_703"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentContinuingOperationsMember" xlink:label="Locator_us-gaap_SegmentContinuingOperationsMember_704"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentOperatingActivitiesDomain_703" xlink:to="Locator_us-gaap_SegmentContinuingOperationsMember_704" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_669"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLossAttributableToRedeemableNoncontrollingInterest" xlink:label="Locator_us-gaap_NetIncomeLossAttributableToRedeemableNoncontrollingInterest_670"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_669" xlink:to="Locator_us-gaap_NetIncomeLossAttributableToRedeemableNoncontrollingInterest_670" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_671"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityForeignCurrencyTranslationAdjustments" xlink:label="Locator_us-gaap_TemporaryEquityForeignCurrencyTranslationAdjustments_672"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_671" xlink:to="Locator_us-gaap_TemporaryEquityForeignCurrencyTranslationAdjustments_672" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_697"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_698"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_697" xlink:to="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_698" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_699"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOperatingActivitiesSegmentAxis" xlink:label="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_700"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_699" xlink:to="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_700" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="Locator_us-gaap_StatementOfStockholdersEquityAbstract_675"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_676"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfStockholdersEquityAbstract_675" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_676" order="1.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="Locator_us-gaap_StatementOfStockholdersEquityAbstract_677"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesTax_678"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfStockholdersEquityAbstract_677" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesTax_678" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="Locator_us-gaap_StatementOfStockholdersEquityAbstract_679"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansTax_680"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfStockholdersEquityAbstract_679" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansTax_680" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="Locator_us-gaap_StatementOfStockholdersEquityAbstract_681"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_682"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfStockholdersEquityAbstract_681" xlink:to="Locator_us-gaap_StatementTable_682" order="4.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RedeemableNoncontrollingInterests">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityDisclosureAbstract" xlink:label="Locator_us-gaap_TemporaryEquityDisclosureAbstract_707"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RedeemableNoncontrollingInterestsTextBlock" xlink:label="Locator_hsic_RedeemableNoncontrollingInterestsTextBlock_708"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TemporaryEquityDisclosureAbstract_707" xlink:to="Locator_hsic_RedeemableNoncontrollingInterestsTextBlock_708" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/EarningsPerShareTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="Locator_us-gaap_EarningsPerShareAbstract_709"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfWeightedAverageNumberOfSharesTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfWeightedAverageNumberOfSharesTableTextBlock_710"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareAbstract_709" xlink:to="Locator_us-gaap_ScheduleOfWeightedAverageNumberOfSharesTableTextBlock_710" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/EarningsPerShareDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="Locator_us-gaap_EarningsPerShareAbstract_711"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_712"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EarningsPerShareAbstract_711" xlink:to="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_712" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_713"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_714"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_713" xlink:to="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_714" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_715"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustmentAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustmentAbstract_716"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_715" xlink:to="Locator_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustmentAbstract_716" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustmentAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustmentAbstract_719"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:label="Locator_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_720"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustmentAbstract_719" xlink:to="Locator_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_720" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_717"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="Locator_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_718"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_717" xlink:to="Locator_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_718" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/SupplementalCashFlowInformationTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowElementsAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowElementsAbstract_725"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfCashFlowSupplementalDisclosuresTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfCashFlowSupplementalDisclosuresTableTextBlock_726"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowElementsAbstract_725" xlink:to="Locator_us-gaap_ScheduleOfCashFlowSupplementalDisclosuresTableTextBlock_726" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/SupplementalCashFlowInformationDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowInformationAbstract_727"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestPaidNet" xlink:label="Locator_us-gaap_InterestPaidNet_728"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowInformationAbstract_727" xlink:to="Locator_us-gaap_InterestPaidNet_728" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowInformationAbstract_729"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxesPaid" xlink:label="Locator_us-gaap_IncomeTaxesPaid_730"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowInformationAbstract_729" xlink:to="Locator_us-gaap_IncomeTaxesPaid_730" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowElementsAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowElementsAbstract_731"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowInformationAbstract_732"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowElementsAbstract_731" xlink:to="Locator_us-gaap_SupplementalCashFlowInformationAbstract_732" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowElementsAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowElementsAbstract_733"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_734"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowElementsAbstract_733" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_734" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/SegmentDataTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="Locator_us-gaap_SegmentReportingAbstract_735"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock" xlink:label="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_736"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentReportingAbstract_735" xlink:to="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_736" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/SegmentDataDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="Locator_us-gaap_StatementBusinessSegmentsAxis_803"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_804"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementBusinessSegmentsAxis_803" xlink:to="Locator_us-gaap_SegmentDomain_804" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_799"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_HealthcareDistributionMember" xlink:label="Locator_hsic_HealthcareDistributionMember_800"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDomain_799" xlink:to="Locator_hsic_HealthcareDistributionMember_800" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_801"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TechnologyMember" xlink:label="Locator_hsic_TechnologyMember_802"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDomain_801" xlink:to="Locator_hsic_TechnologyMember_802" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsAxis" xlink:label="Locator_us-gaap_SubsegmentsAxis_805"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsDomain" xlink:label="Locator_us-gaap_SubsegmentsDomain_806"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsAxis_805" xlink:to="Locator_us-gaap_SubsegmentsDomain_806" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsDomain" xlink:label="Locator_us-gaap_SubsegmentsDomain_807"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_DentalMember" xlink:label="Locator_hsic_DentalMember_808"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsDomain_807" xlink:to="Locator_hsic_DentalMember_808" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsDomain" xlink:label="Locator_us-gaap_SubsegmentsDomain_809"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_MedicalMember" xlink:label="Locator_hsic_MedicalMember_810"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsDomain_809" xlink:to="Locator_hsic_MedicalMember_810" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="Locator_srt_ConsolidationItemsAxis_811"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="Locator_srt_ConsolidationItemsDomain_812"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidationItemsAxis_811" xlink:to="Locator_srt_ConsolidationItemsDomain_812" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="Locator_srt_ConsolidationItemsDomain_813"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="Locator_us-gaap_OperatingSegmentsMember_814"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidationItemsDomain_813" xlink:to="Locator_us-gaap_OperatingSegmentsMember_814" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="Locator_srt_ConsolidationItemsDomain_815"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="Locator_us-gaap_CorporateNonSegmentMember_816"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidationItemsDomain_815" xlink:to="Locator_us-gaap_CorporateNonSegmentMember_816" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsAxis" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_817"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsDomain" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_818"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_817" xlink:to="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_818" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsDomain" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_819"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReportableSubsegmentsMember" xlink:label="Locator_us-gaap_ReportableSubsegmentsMember_820"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_819" xlink:to="Locator_us-gaap_ReportableSubsegmentsMember_820" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="Locator_us-gaap_SegmentReportingAbstract_737"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NumberOfReportableSegments" xlink:label="Locator_us-gaap_NumberOfReportableSegments_738"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentReportingAbstract_737" xlink:to="Locator_us-gaap_NumberOfReportableSegments_738" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="Locator_us-gaap_SegmentReportingAbstract_739"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_740"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentReportingAbstract_739" xlink:to="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_740" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_789"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="Locator_us-gaap_SegmentReportingInformationLineItems_790"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_789" xlink:to="Locator_us-gaap_SegmentReportingInformationLineItems_790" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="Locator_us-gaap_SegmentReportingInformationLineItems_741"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_742"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentReportingInformationLineItems_741" xlink:to="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_742" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="Locator_us-gaap_SegmentReportingInformationLineItems_743"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="Locator_us-gaap_OperatingIncomeLoss_744"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentReportingInformationLineItems_743" xlink:to="Locator_us-gaap_OperatingIncomeLoss_744" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="Locator_us-gaap_SegmentReportingInformationLineItems_745"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NumberOfCountriesInWhichEntityOperates" xlink:label="Locator_us-gaap_NumberOfCountriesInWhichEntityOperates_746"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentReportingInformationLineItems_745" xlink:to="Locator_us-gaap_NumberOfCountriesInWhichEntityOperates_746" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_791"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="Locator_us-gaap_StatementBusinessSegmentsAxis_792"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_791" xlink:to="Locator_us-gaap_StatementBusinessSegmentsAxis_792" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_793"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsAxis" xlink:label="Locator_us-gaap_SubsegmentsAxis_794"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_793" xlink:to="Locator_us-gaap_SubsegmentsAxis_794" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_795"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="Locator_srt_ConsolidationItemsAxis_796"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_795" xlink:to="Locator_srt_ConsolidationItemsAxis_796" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_797"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsAxis" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_798"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_797" xlink:to="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_798" order="4.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/PlansOfRestructuringTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_821"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock" xlink:label="Locator_us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock_822"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_821" xlink:to="Locator_us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock_822" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_823"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock_824"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_823" xlink:to="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock_824" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/PlansOfRestructuringNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis" xlink:label="Locator_srt_StatementScenarioAxis_863"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain" xlink:label="Locator_srt_ScenarioUnspecifiedDomain_864"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_StatementScenarioAxis_863" xlink:to="Locator_srt_ScenarioUnspecifiedDomain_864" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain" xlink:label="Locator_srt_ScenarioUnspecifiedDomain_865"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScenarioPlanMember" xlink:label="Locator_us-gaap_ScenarioPlanMember_866"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ScenarioUnspecifiedDomain_865" xlink:to="Locator_us-gaap_ScenarioPlanMember_866" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_831"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_832"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_831" xlink:to="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_832" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_855"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="Locator_us-gaap_RestructuringPlanAxis_856"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_855" xlink:to="Locator_us-gaap_RestructuringPlanAxis_856" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="Locator_us-gaap_RestructuringPlanAxis_859"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="Locator_us-gaap_RestructuringPlanDomain_860"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringPlanAxis_859" xlink:to="Locator_us-gaap_RestructuringPlanDomain_860" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="Locator_us-gaap_RestructuringPlanDomain_861"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_StrategicPlan2018To2020Member" xlink:label="Locator_hsic_StrategicPlan2018To2020Member_862"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringPlanDomain_861" xlink:to="Locator_hsic_StrategicPlan2018To2020Member_862" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_857"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis" xlink:label="Locator_srt_StatementScenarioAxis_858"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_857" xlink:to="Locator_srt_StatementScenarioAxis_858" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_853"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="Locator_us-gaap_RestructuringCostAndReserveLineItems_854"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_853" xlink:to="Locator_us-gaap_RestructuringCostAndReserveLineItems_854" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="Locator_us-gaap_RestructuringCostAndReserveLineItems_825"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RestructuringAndRelatedCostExpectedPercentageOfWorkforceEliminated" xlink:label="Locator_hsic_RestructuringAndRelatedCostExpectedPercentageOfWorkforceEliminated_826"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringCostAndReserveLineItems_825" xlink:to="Locator_hsic_RestructuringAndRelatedCostExpectedPercentageOfWorkforceEliminated_826" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="Locator_us-gaap_RestructuringCostAndReserveLineItems_827"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringSettlementAndImpairmentProvisions" xlink:label="Locator_us-gaap_RestructuringSettlementAndImpairmentProvisions_828"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringCostAndReserveLineItems_827" xlink:to="Locator_us-gaap_RestructuringSettlementAndImpairmentProvisions_828" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/ComprehensiveIncomeAccumulatedOtherComprehensiveIncomeAndComprehensiveIncomeComponentsDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_867"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_868"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_867" xlink:to="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_868" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_871"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityAbstract" xlink:label="Locator_us-gaap_TemporaryEquityAbstract_872"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_871" xlink:to="Locator_us-gaap_TemporaryEquityAbstract_872" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityAbstract" xlink:label="Locator_us-gaap_TemporaryEquityAbstract_879"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentAttributableToRedeemableNoncontrollingInterestNetOfTax" xlink:label="Locator_hsic_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentAttributableToRedeemableNoncontrollingInterestNetOfTax_880"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TemporaryEquityAbstract_879" xlink:to="Locator_hsic_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentAttributableToRedeemableNoncontrollingInterestNetOfTax_880" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_873"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MinorityInterestAbstract" xlink:label="Locator_us-gaap_MinorityInterestAbstract_874"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_873" xlink:to="Locator_us-gaap_MinorityInterestAbstract_874" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MinorityInterestAbstract" xlink:label="Locator_us-gaap_MinorityInterestAbstract_881"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentAttributableToNonredeemableNoncontrollingInterestsNetOfTax" xlink:label="Locator_hsic_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentAttributableToNonredeemableNoncontrollingInterestsNetOfTax_882"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_MinorityInterestAbstract_881" xlink:to="Locator_hsic_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentAttributableToNonredeemableNoncontrollingInterestsNetOfTax_882" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_875"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AOCIAttributableToParentAbstract" xlink:label="Locator_us-gaap_AOCIAttributableToParentAbstract_876"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_875" xlink:to="Locator_us-gaap_AOCIAttributableToParentAbstract_876" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AOCIAttributableToParentAbstract" xlink:label="Locator_us-gaap_AOCIAttributableToParentAbstract_883"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax_884"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AOCIAttributableToParentAbstract_883" xlink:to="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax_884" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AOCIAttributableToParentAbstract" xlink:label="Locator_us-gaap_AOCIAttributableToParentAbstract_885"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax" xlink:label="Locator_us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax_886"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AOCIAttributableToParentAbstract_885" xlink:to="Locator_us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax_886" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AOCIAttributableToParentAbstract" xlink:label="Locator_us-gaap_AOCIAttributableToParentAbstract_887"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_888"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AOCIAttributableToParentAbstract_887" xlink:to="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_888" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AOCIAttributableToParentAbstract" xlink:label="Locator_us-gaap_AOCIAttributableToParentAbstract_889"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_890"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AOCIAttributableToParentAbstract_889" xlink:to="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_890" order="4.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AOCIAttributableToParentAbstract" xlink:label="Locator_us-gaap_AOCIAttributableToParentAbstract_891"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_892"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AOCIAttributableToParentAbstract_891" xlink:to="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_892" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract" xlink:label="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_877"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AccumulatedOtherComprehensiveIncomeLossNetOfTaxIncludingPortionAttributableToRedeemableAndNonredeemableNoncontrollingInterests" xlink:label="Locator_hsic_AccumulatedOtherComprehensiveIncomeLossNetOfTaxIncludingPortionAttributableToRedeemableAndNonredeemableNoncontrollingInterests_878"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTaxAbstract_877" xlink:to="Locator_hsic_AccumulatedOtherComprehensiveIncomeLossNetOfTaxIncludingPortionAttributableToRedeemableAndNonredeemableNoncontrollingInterests_878" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_869"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_870"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_869" xlink:to="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_870" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_893"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProfitLoss" xlink:label="Locator_us-gaap_ProfitLoss_894"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_893" xlink:to="Locator_us-gaap_ProfitLoss_894" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_895"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax_896"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_895" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax_896" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_897"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentTax_898"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_897" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentTax_898" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_899"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_900"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_899" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_900" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_901"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_902"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_901" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationBeforeTax_902" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_903"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_904"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_903" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_904" order="6.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_905"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_906"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_905" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_906" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_907"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentBeforeTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentBeforeTax_908"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_907" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentBeforeTax_908" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_909"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesTax_910"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_909" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesTax_910" order="9.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_911"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_912"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_911" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_912" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_913"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeTax_914"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_913" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeTax_914" order="11.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_915"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansTax_916"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_915" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansTax_916" order="12.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_917"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_918"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_917" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_918" order="13.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComponentsOfComprehensiveIncomeAbstract" xlink:label="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_919"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_920"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComponentsOfComprehensiveIncomeAbstract_919" xlink:to="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_920" order="14.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RedeemableNoncontrollingInterestsDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityDisclosureAbstract" xlink:label="Locator_us-gaap_TemporaryEquityDisclosureAbstract_951"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_952"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TemporaryEquityDisclosureAbstract_951" xlink:to="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_952" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_955"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityEliminationAsPartofReorganization" xlink:label="Locator_us-gaap_TemporaryEquityEliminationAsPartofReorganization_956"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_955" xlink:to="Locator_us-gaap_TemporaryEquityEliminationAsPartofReorganization_956" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_957"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityStockIssuedDuringPeriodValueNewIssues" xlink:label="Locator_us-gaap_TemporaryEquityStockIssuedDuringPeriodValueNewIssues_958"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_957" xlink:to="Locator_us-gaap_TemporaryEquityStockIssuedDuringPeriodValueNewIssues_958" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_959"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLossAttributableToRedeemableNoncontrollingInterest" xlink:label="Locator_us-gaap_NetIncomeLossAttributableToRedeemableNoncontrollingInterest_960"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_959" xlink:to="Locator_us-gaap_NetIncomeLossAttributableToRedeemableNoncontrollingInterest_960" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_961"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RedeemableNoncontrollingDecreaseFromDistributionsByRedeemableNoncontrollingInterest" xlink:label="Locator_hsic_RedeemableNoncontrollingDecreaseFromDistributionsByRedeemableNoncontrollingInterest_962"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_961" xlink:to="Locator_hsic_RedeemableNoncontrollingDecreaseFromDistributionsByRedeemableNoncontrollingInterest_962" order="5.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_963"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityForeignCurrencyTranslationAdjustments" xlink:label="Locator_us-gaap_TemporaryEquityForeignCurrencyTranslationAdjustments_964"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_963" xlink:to="Locator_us-gaap_TemporaryEquityForeignCurrencyTranslationAdjustments_964" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_965"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TemporaryEquityChangesToRedemptionValue" xlink:label="Locator_hsic_TemporaryEquityChangesToRedemptionValue_966"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_965" xlink:to="Locator_hsic_TemporaryEquityChangesToRedemptionValue_966" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_953"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests" xlink:label="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_954"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_953" xlink:to="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_954" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_967"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests" xlink:label="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_968"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RedeemableNoncontrollingInterestEquityFairValueAbstract_967" xlink:to="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_968" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/FairValueMeasurementsTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="Locator_us-gaap_FairValueDisclosuresAbstract_969"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_970"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueDisclosuresAbstract_969" xlink:to="Locator_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_970" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/FairValueMeasurementsDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityAbstract" xlink:label="Locator_us-gaap_TemporaryEquityAbstract_971"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests" xlink:label="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_972"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TemporaryEquityAbstract_971" xlink:to="Locator_us-gaap_TemporaryEquityCarryingAmountIncludingPortionAttributableToNoncontrollingInterests_972" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="Locator_us-gaap_HedgingDesignationAxis_1097"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="Locator_us-gaap_HedgingDesignationDomain_1098"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_HedgingDesignationAxis_1097" xlink:to="Locator_us-gaap_HedgingDesignationDomain_1098" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="Locator_us-gaap_HedgingDesignationDomain_1099"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="Locator_us-gaap_DesignatedAsHedgingInstrumentMember_1100"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_HedgingDesignationDomain_1099" xlink:to="Locator_us-gaap_DesignatedAsHedgingInstrumentMember_1100" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="Locator_us-gaap_HedgingDesignationDomain_1101"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotDesignatedAsHedgingInstrumentEconomicHedgeMember" xlink:label="Locator_us-gaap_NotDesignatedAsHedgingInstrumentEconomicHedgeMember_1102"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_HedgingDesignationDomain_1101" xlink:to="Locator_us-gaap_NotDesignatedAsHedgingInstrumentEconomicHedgeMember_1102" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="Locator_us-gaap_FairValueDisclosuresAbstract_997"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_998"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueDisclosuresAbstract_997" xlink:to="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_998" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1069"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1070"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1069" xlink:to="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1070" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_973"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentFairValueDisclosureAbstract" xlink:label="Locator_us-gaap_DebtInstrumentFairValueDisclosureAbstract_974"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_973" xlink:to="Locator_us-gaap_DebtInstrumentFairValueDisclosureAbstract_974" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentFairValueDisclosureAbstract" xlink:label="Locator_us-gaap_DebtInstrumentFairValueDisclosureAbstract_983"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentFairValue" xlink:label="Locator_us-gaap_DebtInstrumentFairValue_984"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentFairValueDisclosureAbstract_983" xlink:to="Locator_us-gaap_DebtInstrumentFairValue_984" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_975"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_976"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_975" xlink:to="Locator_us-gaap_AssetsAbstract_976" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_985"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssets" xlink:label="Locator_us-gaap_DerivativeAssets_986"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_985" xlink:to="Locator_us-gaap_DerivativeAssets_986" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_987"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountAsset" xlink:label="Locator_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountAsset_988"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_987" xlink:to="Locator_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountAsset_988" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="Locator_us-gaap_AssetsAbstract_989"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="Locator_us-gaap_AssetsFairValueDisclosure_990"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAbstract_989" xlink:to="Locator_us-gaap_AssetsFairValueDisclosure_990" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_977"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="Locator_us-gaap_LiabilitiesAbstract_978"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_977" xlink:to="Locator_us-gaap_LiabilitiesAbstract_978" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="Locator_us-gaap_LiabilitiesAbstract_991"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilities" xlink:label="Locator_us-gaap_DerivativeLiabilities_992"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAbstract_991" xlink:to="Locator_us-gaap_DerivativeLiabilities_992" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="Locator_us-gaap_LiabilitiesAbstract_993"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability" xlink:label="Locator_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability_994"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAbstract_993" xlink:to="Locator_us-gaap_FairValueDisclosureOffbalanceSheetRisksAmountLiability_994" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="Locator_us-gaap_LiabilitiesAbstract_995"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="Locator_us-gaap_LiabilitiesFairValueDisclosure_996"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesAbstract_995" xlink:to="Locator_us-gaap_LiabilitiesFairValueDisclosure_996" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_979"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityAbstract" xlink:label="Locator_us-gaap_TemporaryEquityAbstract_980"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_979" xlink:to="Locator_us-gaap_TemporaryEquityAbstract_980" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1071"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="Locator_us-gaap_FairValueByMeasurementFrequencyAxis_1072"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1071" xlink:to="Locator_us-gaap_FairValueByMeasurementFrequencyAxis_1072" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="Locator_us-gaap_FairValueByMeasurementFrequencyAxis_1085"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="Locator_us-gaap_FairValueMeasurementFrequencyDomain_1086"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueByMeasurementFrequencyAxis_1085" xlink:to="Locator_us-gaap_FairValueMeasurementFrequencyDomain_1086" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="Locator_us-gaap_FairValueMeasurementFrequencyDomain_1087"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="Locator_us-gaap_FairValueMeasurementsRecurringMember_1088"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueMeasurementFrequencyDomain_1087" xlink:to="Locator_us-gaap_FairValueMeasurementsRecurringMember_1088" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1073"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="Locator_us-gaap_FairValueByFairValueHierarchyLevelAxis_1074"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1073" xlink:to="Locator_us-gaap_FairValueByFairValueHierarchyLevelAxis_1074" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="Locator_us-gaap_FairValueByFairValueHierarchyLevelAxis_1089"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1090"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueByFairValueHierarchyLevelAxis_1089" xlink:to="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1090" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1079"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="Locator_us-gaap_FairValueInputsLevel1Member_1080"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1079" xlink:to="Locator_us-gaap_FairValueInputsLevel1Member_1080" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1081"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="Locator_us-gaap_FairValueInputsLevel2Member_1082"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1081" xlink:to="Locator_us-gaap_FairValueInputsLevel2Member_1082" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1083"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="Locator_us-gaap_FairValueInputsLevel3Member_1084"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1083" xlink:to="Locator_us-gaap_FairValueInputsLevel3Member_1084" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1075"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementBasisAxis" xlink:label="Locator_us-gaap_FairValueByMeasurementBasisAxis_1076"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1075" xlink:to="Locator_us-gaap_FairValueByMeasurementBasisAxis_1076" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementBasisAxis" xlink:label="Locator_us-gaap_FairValueByMeasurementBasisAxis_1091"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosureItemAmountsDomain" xlink:label="Locator_us-gaap_FairValueDisclosureItemAmountsDomain_1092"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueByMeasurementBasisAxis_1091" xlink:to="Locator_us-gaap_FairValueDisclosureItemAmountsDomain_1092" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosureItemAmountsDomain" xlink:label="Locator_us-gaap_FairValueDisclosureItemAmountsDomain_1093"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PortionAtFairValueFairValueDisclosureMember" xlink:label="Locator_us-gaap_PortionAtFairValueFairValueDisclosureMember_1094"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueDisclosureItemAmountsDomain_1093" xlink:to="Locator_us-gaap_PortionAtFairValueFairValueDisclosureMember_1094" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueDisclosureItemAmountsDomain" xlink:label="Locator_us-gaap_FairValueDisclosureItemAmountsDomain_1095"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EstimateOfFairValueFairValueDisclosureMember" xlink:label="Locator_us-gaap_EstimateOfFairValueFairValueDisclosureMember_1096"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueDisclosureItemAmountsDomain_1095" xlink:to="Locator_us-gaap_EstimateOfFairValueFairValueDisclosureMember_1096" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1077"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="Locator_us-gaap_HedgingDesignationAxis_1078"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_1077" xlink:to="Locator_us-gaap_HedgingDesignationAxis_1078" order="4.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/Debt">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_1103"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="Locator_us-gaap_DebtDisclosureTextBlock_1104"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_1103" xlink:to="Locator_us-gaap_DebtDisclosureTextBlock_1104" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtUSTradeAccountsReceivableSecuritizationNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_1125"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1126"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_1125" xlink:to="Locator_us-gaap_DebtInstrumentTable_1126" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1173"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="Locator_us-gaap_VariableRateAxis_1174"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1173" xlink:to="Locator_us-gaap_VariableRateAxis_1174" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="Locator_us-gaap_VariableRateAxis_1177"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="Locator_us-gaap_VariableRateDomain_1178"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_VariableRateAxis_1177" xlink:to="Locator_us-gaap_VariableRateDomain_1178" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="Locator_us-gaap_VariableRateDomain_1179"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AverageAssetBackedCommercialPaperRateMember" xlink:label="Locator_hsic_AverageAssetBackedCommercialPaperRateMember_1180"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_VariableRateDomain_1179" xlink:to="Locator_hsic_AverageAssetBackedCommercialPaperRateMember_1180" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1175"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoanRestructuringModificationAxis" xlink:label="Locator_us-gaap_LoanRestructuringModificationAxis_1176"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1175" xlink:to="Locator_us-gaap_LoanRestructuringModificationAxis_1176" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoanRestructuringModificationAxis" xlink:label="Locator_us-gaap_LoanRestructuringModificationAxis_1185"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoanRestructuringModificationDomain" xlink:label="Locator_us-gaap_LoanRestructuringModificationDomain_1186"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LoanRestructuringModificationAxis_1185" xlink:to="Locator_us-gaap_LoanRestructuringModificationDomain_1186" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoanRestructuringModificationDomain" xlink:label="Locator_us-gaap_LoanRestructuringModificationDomain_1187"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ExtendedMaturityMember" xlink:label="Locator_us-gaap_ExtendedMaturityMember_1188"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LoanRestructuringModificationDomain_1187" xlink:to="Locator_us-gaap_ExtendedMaturityMember_1188" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1169"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1170"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1169" xlink:to="Locator_us-gaap_DebtInstrumentLineItems_1170" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1105"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_DebtPricingCommittmentPeriod" xlink:label="Locator_hsic_DebtPricingCommittmentPeriod_1106"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1105" xlink:to="Locator_hsic_DebtPricingCommittmentPeriod_1106" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1113"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="Locator_us-gaap_DebtInstrumentInterestRateEffectivePercentage_1114"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1113" xlink:to="Locator_us-gaap_DebtInstrumentInterestRateEffectivePercentage_1114" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1115"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_DebtInstrumentVariableRateBasisAtPeriodEnd" xlink:label="Locator_hsic_DebtInstrumentVariableRateBasisAtPeriodEnd_1116"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1115" xlink:to="Locator_hsic_DebtInstrumentVariableRateBasisAtPeriodEnd_1116" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1117"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1" xlink:label="Locator_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_1118"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1117" xlink:to="Locator_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_1118" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1119"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_CommittmentFeeForUsageUpperFacilityLimit" xlink:label="Locator_hsic_CommittmentFeeForUsageUpperFacilityLimit_1120"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1119" xlink:to="Locator_hsic_CommittmentFeeForUsageUpperFacilityLimit_1120" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1121"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_CommittmentFeeForUsageLowerFacilityLimit" xlink:label="Locator_hsic_CommittmentFeeForUsageLowerFacilityLimit_1122"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1121" xlink:to="Locator_hsic_CommittmentFeeForUsageLowerFacilityLimit_1122" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1109"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="Locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_1110"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1109" xlink:to="Locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_1110" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1107"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentMaturityDate" xlink:label="Locator_us-gaap_DebtInstrumentMaturityDate_1108"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1107" xlink:to="Locator_us-gaap_DebtInstrumentMaturityDate_1108" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1111"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities" xlink:label="Locator_hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities_1112"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1111" xlink:to="Locator_hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities_1112" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1171"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_1172"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1171" xlink:to="Locator_us-gaap_LongtermDebtTypeAxis_1172" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_1181"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_1182"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeAxis_1181" xlink:to="Locator_us-gaap_LongtermDebtTypeDomain_1182" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_1183"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_USTradeAccountsReceivableSecuritizationMember" xlink:label="Locator_hsic_USTradeAccountsReceivableSecuritizationMember_1184"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeDomain_1183" xlink:to="Locator_hsic_USTradeAccountsReceivableSecuritizationMember_1184" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RedeemableNoncontrollingInterestsTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TemporaryEquityDisclosureAbstract" xlink:label="Locator_us-gaap_TemporaryEquityDisclosureAbstract_1189"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RedeemableNoncontrollingInterestTableTextBlock" xlink:label="Locator_us-gaap_RedeemableNoncontrollingInterestTableTextBlock_1190"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TemporaryEquityDisclosureAbstract_1189" xlink:to="Locator_us-gaap_RedeemableNoncontrollingInterestTableTextBlock_1190" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/ComprehensiveIncomeTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1191"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_1192"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1191" xlink:to="Locator_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_1192" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1193"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfComprehensiveIncomeLossTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfComprehensiveIncomeLossTableTextBlock_1194"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1193" xlink:to="Locator_us-gaap_ScheduleOfComprehensiveIncomeLossTableTextBlock_1194" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1195"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TotalComprehensiveIncomeNetOfTaxTableTextBlock" xlink:label="Locator_hsic_TotalComprehensiveIncomeNetOfTaxTableTextBlock_1196"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1195" xlink:to="Locator_hsic_TotalComprehensiveIncomeNetOfTaxTableTextBlock_1196" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/StockBasedCompensationTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1197"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_1198"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1197" xlink:to="Locator_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_1198" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1199"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTextBlock" xlink:label="Locator_us-gaap_DisclosureOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTextBlock_1200"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1199" xlink:to="Locator_us-gaap_DisclosureOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTextBlock_1200" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1201"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfSharebasedCompensationRestrictedStockAndRestrictedStockUnitsActivityTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfSharebasedCompensationRestrictedStockAndRestrictedStockUnitsActivityTableTextBlock_1202"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1201" xlink:to="Locator_us-gaap_ScheduleOfSharebasedCompensationRestrictedStockAndRestrictedStockUnitsActivityTableTextBlock_1202" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/StockBasedCompensationNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDiscontinuedOperationsMember" xlink:label="Locator_us-gaap_SegmentDiscontinuedOperationsMember_1301"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_1302"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDiscontinuedOperationsMember_1301" xlink:to="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_1302" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_1303"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AnimalHealthMember" xlink:label="Locator_hsic_AnimalHealthMember_1304"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_1303" xlink:to="Locator_hsic_AnimalHealthMember_1304" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1203"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="Locator_us-gaap_AllocatedShareBasedCompensationExpense_1204"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1203" xlink:to="Locator_us-gaap_AllocatedShareBasedCompensationExpense_1204" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1205"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpenseNetOfTax" xlink:label="Locator_us-gaap_AllocatedShareBasedCompensationExpenseNetOfTax_1206"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1205" xlink:to="Locator_us-gaap_AllocatedShareBasedCompensationExpenseNetOfTax_1206" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1207"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities" xlink:label="Locator_us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities_1208"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1207" xlink:to="Locator_us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities_1208" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1209"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized" xlink:label="Locator_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_1210"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1209" xlink:to="Locator_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_1210" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1211"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1" xlink:label="Locator_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_1212"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1211" xlink:to="Locator_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_1212" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1213"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1214"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1213" xlink:to="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1214" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1297"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="Locator_us-gaap_DisposalGroupClassificationAxis_1298"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1297" xlink:to="Locator_us-gaap_DisposalGroupClassificationAxis_1298" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="Locator_us-gaap_DisposalGroupClassificationAxis_1305"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="Locator_us-gaap_DisposalGroupClassificationDomain_1306"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupClassificationAxis_1305" xlink:to="Locator_us-gaap_DisposalGroupClassificationDomain_1306" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="Locator_us-gaap_DisposalGroupClassificationDomain_1307"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDiscontinuedOperationsMember" xlink:label="Locator_us-gaap_SegmentDiscontinuedOperationsMember_1308"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupClassificationDomain_1307" xlink:to="Locator_us-gaap_SegmentDiscontinuedOperationsMember_1308" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1299"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis" xlink:label="Locator_srt_StatementScenarioAxis_1300"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1299" xlink:to="Locator_srt_StatementScenarioAxis_1300" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis" xlink:label="Locator_srt_StatementScenarioAxis_1327"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain" xlink:label="Locator_srt_ScenarioUnspecifiedDomain_1328"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_StatementScenarioAxis_1327" xlink:to="Locator_srt_ScenarioUnspecifiedDomain_1328" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain" xlink:label="Locator_srt_ScenarioUnspecifiedDomain_1329"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioForecastMember" xlink:label="Locator_srt_ScenarioForecastMember_1330"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ScenarioUnspecifiedDomain_1329" xlink:to="Locator_srt_ScenarioForecastMember_1330" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1291"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1292"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1291" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1292" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1215"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_1216"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1215" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_1216" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1217"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PeriodOverWhichEarningsPerSharePerformanceIsMeasuredAgainstSpecifiedTargets" xlink:label="Locator_hsic_PeriodOverWhichEarningsPerSharePerformanceIsMeasuredAgainstSpecifiedTargets_1218"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1217" xlink:to="Locator_hsic_PeriodOverWhichEarningsPerSharePerformanceIsMeasuredAgainstSpecifiedTargets_1218" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1219"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsPeriodIncreaseDecrease" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsPeriodIncreaseDecrease_1220"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1219" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsPeriodIncreaseDecrease_1220" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1221"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_IncreaseDecreaseInPricePerShare" xlink:label="Locator_hsic_IncreaseDecreaseInPricePerShare_1222"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1221" xlink:to="Locator_hsic_IncreaseDecreaseInPricePerShare_1222" order="4.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1223"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_StockBasedCompensationPercentageOfOptionsVestPerYear" xlink:label="Locator_hsic_StockBasedCompensationPercentageOfOptionsVestPerYear_1224"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1223" xlink:to="Locator_hsic_StockBasedCompensationPercentageOfOptionsVestPerYear_1224" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1225"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_StockBasedCompensationPercentageOfOptionsVestPerYearFirstAnniversary" xlink:label="Locator_hsic_StockBasedCompensationPercentageOfOptionsVestPerYearFirstAnniversary_1226"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1225" xlink:to="Locator_hsic_StockBasedCompensationPercentageOfOptionsVestPerYearFirstAnniversary_1226" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1227"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_StockBasedCompensationPercentageOfOptionsVestPerYearSecondAnniversary" xlink:label="Locator_hsic_StockBasedCompensationPercentageOfOptionsVestPerYearSecondAnniversary_1228"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1227" xlink:to="Locator_hsic_StockBasedCompensationPercentageOfOptionsVestPerYearSecondAnniversary_1228" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1229"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_1230"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1229" xlink:to="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_1230" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1231"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod" xlink:label="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_1232"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1231" xlink:to="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_1232" order="9.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1293"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="Locator_us-gaap_AwardTypeAxis_1294"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1293" xlink:to="Locator_us-gaap_AwardTypeAxis_1294" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="Locator_us-gaap_AwardTypeAxis_1309"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1310"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AwardTypeAxis_1309" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1310" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1311"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RestrictedStockAndRestrictedStockUnitAwardsMember" xlink:label="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_1312"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1311" xlink:to="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_1312" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RestrictedStockAndRestrictedStockUnitAwardsMember" xlink:label="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_1313"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TimeBasedRestrictedStockRestrictedUnitsMember" xlink:label="Locator_hsic_TimeBasedRestrictedStockRestrictedUnitsMember_1314"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_1313" xlink:to="Locator_hsic_TimeBasedRestrictedStockRestrictedUnitsMember_1314" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RestrictedStockAndRestrictedStockUnitAwardsMember" xlink:label="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_1315"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PerformanceBasedRestrictedStockRestrictedUnitsMember" xlink:label="Locator_hsic_PerformanceBasedRestrictedStockRestrictedUnitsMember_1316"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_1315" xlink:to="Locator_hsic_PerformanceBasedRestrictedStockRestrictedUnitsMember_1316" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1295"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="Locator_us-gaap_PlanNameAxis_1296"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1295" xlink:to="Locator_us-gaap_PlanNameAxis_1296" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="Locator_us-gaap_PlanNameAxis_1317"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="Locator_us-gaap_PlanNameDomain_1318"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_PlanNameAxis_1317" xlink:to="Locator_us-gaap_PlanNameDomain_1318" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="Locator_us-gaap_PlanNameDomain_1319"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermIncentiveProgramMember" xlink:label="Locator_hsic_LongTermIncentiveProgramMember_1320"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_PlanNameDomain_1319" xlink:to="Locator_hsic_LongTermIncentiveProgramMember_1320" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermIncentiveProgramMember" xlink:label="Locator_hsic_LongTermIncentiveProgramMember_1321"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_StockIncentivePlanMember" xlink:label="Locator_hsic_StockIncentivePlanMember_1322"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_LongTermIncentiveProgramMember_1321" xlink:to="Locator_hsic_StockIncentivePlanMember_1322" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermIncentiveProgramMember" xlink:label="Locator_hsic_LongTermIncentiveProgramMember_1323"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_NonEmployeeDirectorStockIncentivePlanMember" xlink:label="Locator_hsic_NonEmployeeDirectorStockIncentivePlanMember_1324"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_LongTermIncentiveProgramMember_1323" xlink:to="Locator_hsic_NonEmployeeDirectorStockIncentivePlanMember_1324" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermIncentiveProgramMember" xlink:label="Locator_hsic_LongTermIncentiveProgramMember_1325"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermIncentiveProgram2021Member" xlink:label="Locator_hsic_LongTermIncentiveProgram2021Member_1326"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_LongTermIncentiveProgramMember_1325" xlink:to="Locator_hsic_LongTermIncentiveProgram2021Member_1326" order="3.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOMEunaudited">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1331"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProfitLoss" xlink:label="Locator_us-gaap_ProfitLoss_1332"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1331" xlink:to="Locator_us-gaap_ProfitLoss_1332" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1333"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1334"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1333" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1334" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1341"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_1342"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1341" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_1342" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1343"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_1344"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1343" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_1344" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1345"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_1346"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1345" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_1346" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1347"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_1348"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1347" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_1348" order="4.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1349"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTax_1350"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_1349" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeLossNetOfTax_1350" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1335"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_1336"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1335" xlink:to="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_1336" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1337"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1338"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1337" xlink:to="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1338" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1351"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLossAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_NetIncomeLossAttributableToNoncontrollingInterest_1352"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1351" xlink:to="Locator_us-gaap_NetIncomeLossAttributableToNoncontrollingInterest_1352" order="1.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1353"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToNoncontrollingInterest_1354"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1353" xlink:to="Locator_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToNoncontrollingInterest_1354" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1355"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest_1356"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterestAbstract_1355" xlink:to="Locator_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest_1356" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1339"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTax_1340"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_1339" xlink:to="Locator_us-gaap_ComprehensiveIncomeNetOfTax_1340" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_1377"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShortTermDebtTextBlock" xlink:label="Locator_us-gaap_ScheduleOfShortTermDebtTextBlock_1378"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_1377" xlink:to="Locator_us-gaap_ScheduleOfShortTermDebtTextBlock_1378" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_1379"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:label="Locator_us-gaap_ScheduleOfDebtInstrumentsTextBlock_1380"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_1379" xlink:to="Locator_us-gaap_ScheduleOfDebtInstrumentsTextBlock_1380" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_1381"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ScheduleOfPrivatePlacementFacilitiesDebtTableTextBlock" xlink:label="Locator_hsic_ScheduleOfPrivatePlacementFacilitiesDebtTableTextBlock_1382"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_1381" xlink:to="Locator_hsic_ScheduleOfPrivatePlacementFacilitiesDebtTableTextBlock_1382" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/ComprehensiveIncomeTotalComprehensiveIncomeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1383"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract" xlink:label="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1384"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterestAbstract_1383" xlink:to="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1384" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract" xlink:label="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1385"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTax_1386"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1385" xlink:to="Locator_us-gaap_ComprehensiveIncomeNetOfTax_1386" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract" xlink:label="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1387"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComprehensiveIncomeAttributableToNoncontrollingInterestsExcludingComprehensiveIncomeAttributableToRedeemableNoncontrollingInterests" xlink:label="Locator_hsic_ComprehensiveIncomeAttributableToNoncontrollingInterestsExcludingComprehensiveIncomeAttributableToRedeemableNoncontrollingInterests_1388"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1387" xlink:to="Locator_hsic_ComprehensiveIncomeAttributableToNoncontrollingInterestsExcludingComprehensiveIncomeAttributableToRedeemableNoncontrollingInterests_1388" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract" xlink:label="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1389"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComprehensiveIncomeNetOfTaxAttributableToRedeemableNoncontrollingInterest" xlink:label="Locator_hsic_ComprehensiveIncomeNetOfTaxAttributableToRedeemableNoncontrollingInterest_1390"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1389" xlink:to="Locator_hsic_ComprehensiveIncomeNetOfTaxAttributableToRedeemableNoncontrollingInterest_1390" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract" xlink:label="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1391"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:label="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_1392"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_ComprehensiveIncomeNetOfApplicableTaxesAbstract_1391" xlink:to="Locator_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_1392" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/BusinessAcquisitionsNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationsAbstract_1405"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1406"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationsAbstract_1405" xlink:to="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1406" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1431"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_1432"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1431" xlink:to="Locator_srt_RangeAxis_1432" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_1437"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1438"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeAxis_1437" xlink:to="Locator_srt_RangeMember_1438" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1439"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember" xlink:label="Locator_srt_MinimumMember_1440"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_1439" xlink:to="Locator_srt_MinimumMember_1440" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1441"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember" xlink:label="Locator_srt_MaximumMember_1442"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_1441" xlink:to="Locator_srt_MaximumMember_1442" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1427"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="Locator_us-gaap_BusinessAcquisitionLineItems_1428"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1427" xlink:to="Locator_us-gaap_BusinessAcquisitionLineItems_1428" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="Locator_us-gaap_BusinessAcquisitionLineItems_1399"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired" xlink:label="Locator_us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired_1400"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionLineItems_1399" xlink:to="Locator_us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired_1400" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="Locator_us-gaap_BusinessAcquisitionLineItems_1401"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionDescriptionOfAcquiredEntity" xlink:label="Locator_us-gaap_BusinessAcquisitionDescriptionOfAcquiredEntity_1402"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionLineItems_1401" xlink:to="Locator_us-gaap_BusinessAcquisitionDescriptionOfAcquiredEntity_1402" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1429"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="Locator_us-gaap_BusinessAcquisitionAxis_1430"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1429" xlink:to="Locator_us-gaap_BusinessAcquisitionAxis_1430" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="Locator_us-gaap_BusinessAcquisitionAxis_1433"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_1434"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionAxis_1433" xlink:to="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_1434" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_1435"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SeriesOfIndividuallyImmaterialBusinessAcquisitionsMember" xlink:label="Locator_us-gaap_SeriesOfIndividuallyImmaterialBusinessAcquisitionsMember_1436"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_1435" xlink:to="Locator_us-gaap_SeriesOfIndividuallyImmaterialBusinessAcquisitionsMember_1436" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtRevolvingCreditAgreement364DayCreditAgreementAndOtherShortTermCreditLinesNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_1469"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="Locator_us-gaap_LineOfCreditFacilityTable_1470"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_1469" xlink:to="Locator_us-gaap_LineOfCreditFacilityTable_1470" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="Locator_us-gaap_LineOfCreditFacilityTable_1511"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1512"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityTable_1511" xlink:to="Locator_us-gaap_LineOfCreditFacilityLineItems_1512" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1443"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityInitiationDate1" xlink:label="Locator_us-gaap_LineOfCreditFacilityInitiationDate1_1444"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1443" xlink:to="Locator_us-gaap_LineOfCreditFacilityInitiationDate1_1444" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1445"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="Locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_1446"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1445" xlink:to="Locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_1446" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1447"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityExpirationDate1" xlink:label="Locator_us-gaap_LineOfCreditFacilityExpirationDate1_1448"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1447" xlink:to="Locator_us-gaap_LineOfCreditFacilityExpirationDate1_1448" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1451"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LettersOfCreditOutstandingAmount" xlink:label="Locator_us-gaap_LettersOfCreditOutstandingAmount_1452"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1451" xlink:to="Locator_us-gaap_LettersOfCreditOutstandingAmount_1452" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1453"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityInterestRateAtPeriodEnd" xlink:label="Locator_us-gaap_LineOfCreditFacilityInterestRateAtPeriodEnd_1454"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1453" xlink:to="Locator_us-gaap_LineOfCreditFacilityInterestRateAtPeriodEnd_1454" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1455"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityExpirationPeriod" xlink:label="Locator_us-gaap_LineOfCreditFacilityExpirationPeriod_1456"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1455" xlink:to="Locator_us-gaap_LineOfCreditFacilityExpirationPeriod_1456" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1457"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityCurrentBorrowingCapacity" xlink:label="Locator_us-gaap_LineOfCreditFacilityCurrentBorrowingCapacity_1458"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1457" xlink:to="Locator_us-gaap_LineOfCreditFacilityCurrentBorrowingCapacity_1458" order="8.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1459"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity" xlink:label="Locator_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_1460"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1459" xlink:to="Locator_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_1460" order="9.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1461"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityInterestRateDescription" xlink:label="Locator_us-gaap_LineOfCreditFacilityInterestRateDescription_1462"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1461" xlink:to="Locator_us-gaap_LineOfCreditFacilityInterestRateDescription_1462" order="10.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1463"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityDescription" xlink:label="Locator_us-gaap_LineOfCreditFacilityDescription_1464"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1463" xlink:to="Locator_us-gaap_LineOfCreditFacilityDescription_1464" order="11.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1465"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="Locator_us-gaap_RepaymentsOfLongTermDebt_1466"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1465" xlink:to="Locator_us-gaap_RepaymentsOfLongTermDebt_1466" order="12.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_1449"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermBorrowings" xlink:label="Locator_us-gaap_ShortTermBorrowings_1450"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_1449" xlink:to="Locator_us-gaap_ShortTermBorrowings_1450" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="Locator_us-gaap_LineOfCreditFacilityTable_1513"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="Locator_us-gaap_CreditFacilityAxis_1514"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityTable_1513" xlink:to="Locator_us-gaap_CreditFacilityAxis_1514" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="Locator_us-gaap_CreditFacilityAxis_1515"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="Locator_us-gaap_CreditFacilityDomain_1516"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_CreditFacilityAxis_1515" xlink:to="Locator_us-gaap_CreditFacilityDomain_1516" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="Locator_us-gaap_CreditFacilityDomain_1517"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_1518"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_CreditFacilityDomain_1517" xlink:to="Locator_us-gaap_LineOfCreditMember_1518" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_1519"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="Locator_us-gaap_RevolvingCreditFacilityMember_1520"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditMember_1519" xlink:to="Locator_us-gaap_RevolvingCreditFacilityMember_1520" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="Locator_us-gaap_RevolvingCreditFacilityMember_1525"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RevolvingCreditFacilityApril2022Member" xlink:label="Locator_hsic_RevolvingCreditFacilityApril2022Member_1526"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RevolvingCreditFacilityMember_1525" xlink:to="Locator_hsic_RevolvingCreditFacilityApril2022Member_1526" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_1521"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ThreeHundredSixtyFourDayCreditAgreementMember" xlink:label="Locator_hsic_ThreeHundredSixtyFourDayCreditAgreementMember_1522"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditMember_1521" xlink:to="Locator_hsic_ThreeHundredSixtyFourDayCreditAgreementMember_1522" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_1523"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_VariousBankCreditLinesMember" xlink:label="Locator_hsic_VariousBankCreditLinesMember_1524"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditMember_1523" xlink:to="Locator_hsic_VariousBankCreditLinesMember_1524" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/IncomeTaxesNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_1527"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:label="Locator_us-gaap_EffectiveIncomeTaxRateContinuingOperations_1528"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_1527" xlink:to="Locator_us-gaap_EffectiveIncomeTaxRateContinuingOperations_1528" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_1529"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_UnrecognizedTaxBenefitsIncludingAccruedInterest" xlink:label="Locator_hsic_UnrecognizedTaxBenefitsIncludingAccruedInterest_1530"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_1529" xlink:to="Locator_hsic_UnrecognizedTaxBenefitsIncludingAccruedInterest_1530" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_1531"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate" xlink:label="Locator_us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate_1532"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_1531" xlink:to="Locator_us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate_1532" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_1533"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherInformationPertainingToIncomeTaxes" xlink:label="Locator_us-gaap_OtherInformationPertainingToIncomeTaxes_1534"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_1533" xlink:to="Locator_us-gaap_OtherInformationPertainingToIncomeTaxes_1534" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_1535"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsInterestOnIncomeTaxesAccrued" xlink:label="Locator_us-gaap_UnrecognizedTaxBenefitsInterestOnIncomeTaxesAccrued_1536"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_1535" xlink:to="Locator_us-gaap_UnrecognizedTaxBenefitsInterestOnIncomeTaxesAccrued_1536" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_1537"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAccrued" xlink:label="Locator_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAccrued_1538"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_1537" xlink:to="Locator_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAccrued_1538" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="Locator_us-gaap_IncomeTaxDisclosureAbstract_1539"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationTable" xlink:label="Locator_us-gaap_IncomeTaxExaminationTable_1540"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxDisclosureAbstract_1539" xlink:to="Locator_us-gaap_IncomeTaxExaminationTable_1540" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationTable" xlink:label="Locator_us-gaap_IncomeTaxExaminationTable_1559"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationLineItems" xlink:label="Locator_us-gaap_IncomeTaxExaminationLineItems_1560"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxExaminationTable_1559" xlink:to="Locator_us-gaap_IncomeTaxExaminationLineItems_1560" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationLineItems" xlink:label="Locator_us-gaap_IncomeTaxExaminationLineItems_1541"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxReconciliationTaxSettlements" xlink:label="Locator_us-gaap_IncomeTaxReconciliationTaxSettlements_1542"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxExaminationLineItems_1541" xlink:to="Locator_us-gaap_IncomeTaxReconciliationTaxSettlements_1542" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationLineItems" xlink:label="Locator_us-gaap_IncomeTaxExaminationLineItems_1543"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsInterestOnIncomeTaxesExpense" xlink:label="Locator_us-gaap_UnrecognizedTaxBenefitsInterestOnIncomeTaxesExpense_1544"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxExaminationLineItems_1543" xlink:to="Locator_us-gaap_UnrecognizedTaxBenefitsInterestOnIncomeTaxesExpense_1544" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationTable" xlink:label="Locator_us-gaap_IncomeTaxExaminationTable_1561"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityNameAxis" xlink:label="Locator_us-gaap_IncomeTaxAuthorityNameAxis_1562"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxExaminationTable_1561" xlink:to="Locator_us-gaap_IncomeTaxAuthorityNameAxis_1562" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityNameAxis" xlink:label="Locator_us-gaap_IncomeTaxAuthorityNameAxis_1563"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="Locator_us-gaap_IncomeTaxAuthorityNameDomain_1564"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxAuthorityNameAxis_1563" xlink:to="Locator_us-gaap_IncomeTaxAuthorityNameDomain_1564" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="Locator_us-gaap_IncomeTaxAuthorityNameDomain_1565"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InternalRevenueServiceIRSMember" xlink:label="Locator_us-gaap_InternalRevenueServiceIRSMember_1566"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeTaxAuthorityNameDomain_1565" xlink:to="Locator_us-gaap_InternalRevenueServiceIRSMember_1566" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DerivativesAndHedgingActivitiesNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="Locator_us-gaap_VariableRateAxis_1673"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="Locator_us-gaap_VariableRateDomain_1674"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_VariableRateAxis_1673" xlink:to="Locator_us-gaap_VariableRateDomain_1674" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="Locator_us-gaap_VariableRateDomain_1675"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LondonInterbankOfferedRateLiborSwapRateMember" xlink:label="Locator_us-gaap_LondonInterbankOfferedRateLiborSwapRateMember_1676"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_VariableRateDomain_1675" xlink:to="Locator_us-gaap_LondonInterbankOfferedRateLiborSwapRateMember_1676" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="Locator_us-gaap_VariableRateDomain_1677"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BaseRateMember" xlink:label="Locator_us-gaap_BaseRateMember_1678"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_VariableRateDomain_1677" xlink:to="Locator_us-gaap_BaseRateMember_1678" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="Locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_1567"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1568"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_1567" xlink:to="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1568" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1657"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1658"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1657" xlink:to="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1658" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1569"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ObjectivesForUsingNetInvestmentHedgingInstruments" xlink:label="Locator_us-gaap_ObjectivesForUsingNetInvestmentHedgingInstruments_1570"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1569" xlink:to="Locator_us-gaap_ObjectivesForUsingNetInvestmentHedgingInstruments_1570" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1571"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DescriptionOfNetInvestmentsHedged" xlink:label="Locator_us-gaap_DescriptionOfNetInvestmentsHedged_1572"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1571" xlink:to="Locator_us-gaap_DescriptionOfNetInvestmentsHedged_1572" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1573"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DescriptionOfLocationOfGainLossOnNetInvestmentHedgesInFinancialStatements" xlink:label="Locator_us-gaap_DescriptionOfLocationOfGainLossOnNetInvestmentHedgesInFinancialStatements_1574"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1573" xlink:to="Locator_us-gaap_DescriptionOfLocationOfGainLossOnNetInvestmentHedgesInFinancialStatements_1574" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1575"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeMaturityDates" xlink:label="Locator_us-gaap_DerivativeMaturityDates_1576"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1575" xlink:to="Locator_us-gaap_DerivativeMaturityDates_1576" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1577"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeNotionalAmount" xlink:label="Locator_us-gaap_DerivativeNotionalAmount_1578"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1577" xlink:to="Locator_us-gaap_DerivativeNotionalAmount_1578" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1579"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeExcludedComponentGainLossRecognizedInEarnings" xlink:label="Locator_us-gaap_DerivativeExcludedComponentGainLossRecognizedInEarnings_1580"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1579" xlink:to="Locator_us-gaap_DerivativeExcludedComponentGainLossRecognizedInEarnings_1580" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1581"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInceptionDates" xlink:label="Locator_us-gaap_DerivativeInceptionDates_1582"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1581" xlink:to="Locator_us-gaap_DerivativeInceptionDates_1582" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1583"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeDescriptionOfObjective" xlink:label="Locator_us-gaap_DerivativeDescriptionOfObjective_1584"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1583" xlink:to="Locator_us-gaap_DerivativeDescriptionOfObjective_1584" order="8.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1585"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeVariableInterestRate" xlink:label="Locator_us-gaap_DerivativeVariableInterestRate_1586"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1585" xlink:to="Locator_us-gaap_DerivativeVariableInterestRate_1586" order="9.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1587"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeBasisSpreadOnVariableRate" xlink:label="Locator_us-gaap_DerivativeBasisSpreadOnVariableRate_1588"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1587" xlink:to="Locator_us-gaap_DerivativeBasisSpreadOnVariableRate_1588" order="10.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1589"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeGainOnDerivative" xlink:label="Locator_us-gaap_DerivativeGainOnDerivative_1590"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1589" xlink:to="Locator_us-gaap_DerivativeGainOnDerivative_1590" order="11.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1591"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge" xlink:label="Locator_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge_1592"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1591" xlink:to="Locator_us-gaap_MaximumLengthOfTimeForeignCurrencyCashFlowHedge_1592" order="12.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1593"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeTypeOfInstrument" xlink:label="Locator_us-gaap_DerivativeTypeOfInstrument_1594"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossLineItems_1593" xlink:to="Locator_us-gaap_DerivativeTypeOfInstrument_1594" order="13.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1659"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_1660"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1659" xlink:to="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_1660" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_1667"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="Locator_us-gaap_HedgingRelationshipDomain_1668"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_1667" xlink:to="Locator_us-gaap_HedgingRelationshipDomain_1668" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="Locator_us-gaap_HedgingRelationshipDomain_1669"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetInvestmentHedgingMember" xlink:label="Locator_us-gaap_NetInvestmentHedgingMember_1670"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_HedgingRelationshipDomain_1669" xlink:to="Locator_us-gaap_NetInvestmentHedgingMember_1670" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1661"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="Locator_us-gaap_DerivativeInstrumentRiskAxis_1662"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1661" xlink:to="Locator_us-gaap_DerivativeInstrumentRiskAxis_1662" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="Locator_us-gaap_DerivativeInstrumentRiskAxis_1681"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="Locator_us-gaap_DerivativeContractTypeDomain_1682"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentRiskAxis_1681" xlink:to="Locator_us-gaap_DerivativeContractTypeDomain_1682" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="Locator_us-gaap_DerivativeContractTypeDomain_1671"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignExchangeForwardMember" xlink:label="Locator_us-gaap_ForeignExchangeForwardMember_1672"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeContractTypeDomain_1671" xlink:to="Locator_us-gaap_ForeignExchangeForwardMember_1672" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1663"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="Locator_us-gaap_HedgingDesignationAxis_1664"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1663" xlink:to="Locator_us-gaap_HedgingDesignationAxis_1664" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="Locator_us-gaap_HedgingDesignationAxis_1679"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="Locator_us-gaap_HedgingDesignationDomain_1680"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_HedgingDesignationAxis_1679" xlink:to="Locator_us-gaap_HedgingDesignationDomain_1680" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="Locator_us-gaap_HedgingDesignationDomain_1683"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="Locator_us-gaap_DesignatedAsHedgingInstrumentMember_1684"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_HedgingDesignationDomain_1683" xlink:to="Locator_us-gaap_DesignatedAsHedgingInstrumentMember_1684" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="Locator_us-gaap_HedgingDesignationDomain_1685"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotDesignatedAsHedgingInstrumentEconomicHedgeMember" xlink:label="Locator_us-gaap_NotDesignatedAsHedgingInstrumentEconomicHedgeMember_1686"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_HedgingDesignationDomain_1685" xlink:to="Locator_us-gaap_NotDesignatedAsHedgingInstrumentEconomicHedgeMember_1686" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1665"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="Locator_us-gaap_VariableRateAxis_1666"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1665" xlink:to="Locator_us-gaap_VariableRateAxis_1666" order="4.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LegalProceedings">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="Locator_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_1687"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LegalMattersAndContingenciesTextBlock" xlink:label="Locator_us-gaap_LegalMattersAndContingenciesTextBlock_1688"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_1687" xlink:to="Locator_us-gaap_LegalMattersAndContingenciesTextBlock_1688" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LegalProceedingsNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_1829"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1830"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeAxis_1829" xlink:to="Locator_srt_RangeMember_1830" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1831"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember" xlink:label="Locator_srt_MaximumMember_1832"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_1831" xlink:to="Locator_srt_MaximumMember_1832" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="Locator_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_1719"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="Locator_us-gaap_LossContingenciesTable_1720"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_1719" xlink:to="Locator_us-gaap_LossContingenciesTable_1720" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="Locator_us-gaap_LossContingenciesTable_1791"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="Locator_us-gaap_LossContingenciesLineItems_1792"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingenciesTable_1791" xlink:to="Locator_us-gaap_LossContingenciesLineItems_1792" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="Locator_us-gaap_LossContingenciesLineItems_1689"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1690"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingenciesLineItems_1689" xlink:to="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1690" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1693"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyLawsuitFilingDate" xlink:label="Locator_us-gaap_LossContingencyLawsuitFilingDate_1694"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1693" xlink:to="Locator_us-gaap_LossContingencyLawsuitFilingDate_1694" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1695"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNameOfDefendant" xlink:label="Locator_us-gaap_LossContingencyNameOfDefendant_1696"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1695" xlink:to="Locator_us-gaap_LossContingencyNameOfDefendant_1696" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1697"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber" xlink:label="Locator_us-gaap_LossContingencyPendingClaimsNumber_1698"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1697" xlink:to="Locator_us-gaap_LossContingencyPendingClaimsNumber_1698" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1699"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNameOfPlaintiff" xlink:label="Locator_us-gaap_LossContingencyNameOfPlaintiff_1700"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1699" xlink:to="Locator_us-gaap_LossContingencyNameOfPlaintiff_1700" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1701"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyAllegations" xlink:label="Locator_us-gaap_LossContingencyAllegations_1702"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1701" xlink:to="Locator_us-gaap_LossContingencyAllegations_1702" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1703"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainLossRelatedToLitigationSettlement" xlink:label="Locator_us-gaap_GainLossRelatedToLitigationSettlement_1704"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1703" xlink:to="Locator_us-gaap_GainLossRelatedToLitigationSettlement_1704" order="6.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1705"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencySettlementAgreementTerms" xlink:label="Locator_us-gaap_LossContingencySettlementAgreementTerms_1706"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1705" xlink:to="Locator_us-gaap_LossContingencySettlementAgreementTerms_1706" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1707"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_DonationAmountToPainManagementEducationFoundation" xlink:label="Locator_hsic_DonationAmountToPainManagementEducationFoundation_1708"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1707" xlink:to="Locator_hsic_DonationAmountToPainManagementEducationFoundation_1708" order="8.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1709"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedToOtherParty" xlink:label="Locator_us-gaap_LitigationSettlementAmountAwardedToOtherParty_1710"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1709" xlink:to="Locator_us-gaap_LitigationSettlementAmountAwardedToOtherParty_1710" order="9.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1711"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1712"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1711" xlink:to="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1712" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1713"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_MaximumSalesOfOpioidsInNorthAmericaPercentage" xlink:label="Locator_hsic_MaximumSalesOfOpioidsInNorthAmericaPercentage_1714"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1713" xlink:to="Locator_hsic_MaximumSalesOfOpioidsInNorthAmericaPercentage_1714" order="11.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1715"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyManagementsAssessmentAndProcess" xlink:label="Locator_us-gaap_LossContingencyManagementsAssessmentAndProcess_1716"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1715" xlink:to="Locator_us-gaap_LossContingencyManagementsAssessmentAndProcess_1716" order="12.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyInformationAboutLitigationMattersAbstract" xlink:label="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1717"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PeriodOfTimeActionIsStayed" xlink:label="Locator_hsic_PeriodOfTimeActionIsStayed_1718"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingencyInformationAboutLitigationMattersAbstract_1717" xlink:to="Locator_hsic_PeriodOfTimeActionIsStayed_1718" order="13.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="Locator_us-gaap_LossContingenciesTable_1793"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseAxis" xlink:label="Locator_srt_LitigationCaseAxis_1794"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingenciesTable_1793" xlink:to="Locator_srt_LitigationCaseAxis_1794" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseAxis" xlink:label="Locator_srt_LitigationCaseAxis_1799"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1800"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseAxis_1799" xlink:to="Locator_srt_LitigationCaseTypeDomain_1800" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1801"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ArcherAndWhiteSalesIncVCollectivelyDanaherDefendantsMember" xlink:label="Locator_hsic_ArcherAndWhiteSalesIncVCollectivelyDanaherDefendantsMember_1802"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1801" xlink:to="Locator_hsic_ArcherAndWhiteSalesIncVCollectivelyDanaherDefendantsMember_1802" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1803"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ArcherFiledAmendedComplaintAddingPattersonAndBencoAsDefendantsMember" xlink:label="Locator_hsic_ArcherFiledAmendedComplaintAddingPattersonAndBencoAsDefendantsMember_1804"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1803" xlink:to="Locator_hsic_ArcherFiledAmendedComplaintAddingPattersonAndBencoAsDefendantsMember_1804" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1805"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ArcherFiledSecondAmendedComplaintUnderSealMember" xlink:label="Locator_hsic_ArcherFiledSecondAmendedComplaintUnderSealMember_1806"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1805" xlink:to="Locator_hsic_ArcherFiledSecondAmendedComplaintUnderSealMember_1806" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1807"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_IqDentalSupplyIncVHenryScheinIncPattersonCompaniesIncMember" xlink:label="Locator_hsic_IqDentalSupplyIncVHenryScheinIncPattersonCompaniesIncMember_1808"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1807" xlink:to="Locator_hsic_IqDentalSupplyIncVHenryScheinIncPattersonCompaniesIncMember_1808" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1809"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_UnitedStatesFederalTradeCommissionMember" xlink:label="Locator_hsic_UnitedStatesFederalTradeCommissionMember_1810"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1809" xlink:to="Locator_hsic_UnitedStatesFederalTradeCommissionMember_1810" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1811"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_SalkowitzVHenryScheinIncEtAlMember" xlink:label="Locator_hsic_SalkowitzVHenryScheinIncEtAlMember_1812"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1811" xlink:to="Locator_hsic_SalkowitzVHenryScheinIncEtAlMember_1812" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1813"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_MarionDiagnosticCenterLlcVDickinsonAndCo318Cv01509SdIllMember" xlink:label="Locator_hsic_MarionDiagnosticCenterLlcVDickinsonAndCo318Cv01509SdIllMember_1814"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1813" xlink:to="Locator_hsic_MarionDiagnosticCenterLlcVDickinsonAndCo318Cv01509SdIllMember_1814" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1815"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TheCountyOfSummitOhioEtAlVPurduePharmaLpEtAlMember" xlink:label="Locator_hsic_TheCountyOfSummitOhioEtAlVPurduePharmaLpEtAlMember_1816"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1815" xlink:to="Locator_hsic_TheCountyOfSummitOhioEtAlVPurduePharmaLpEtAlMember_1816" order="8.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1817"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ActionsConsolidatedInTheMultiDistrictLitigationMember" xlink:label="Locator_hsic_ActionsConsolidatedInTheMultiDistrictLitigationMember_1818"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1817" xlink:to="Locator_hsic_ActionsConsolidatedInTheMultiDistrictLitigationMember_1818" order="9.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1819"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_CityOfHollywoodPoliceOfficersRetirementSystemVHenryScheinIncCovetrusIncAndBenjaminShawAndChristineKomolaMember" xlink:label="Locator_hsic_CityOfHollywoodPoliceOfficersRetirementSystemVHenryScheinIncCovetrusIncAndBenjaminShawAndChristineKomolaMember_1820"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1819" xlink:to="Locator_hsic_CityOfHollywoodPoliceOfficersRetirementSystemVHenryScheinIncCovetrusIncAndBenjaminShawAndChristineKomolaMember_1820" order="10.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1821"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_FrankFinazzoAgainstVariousPresentAndFormerDirectorsAndOfficersOfHenryScheinMember" xlink:label="Locator_hsic_FrankFinazzoAgainstVariousPresentAndFormerDirectorsAndOfficersOfHenryScheinMember_1822"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1821" xlink:to="Locator_hsic_FrankFinazzoAgainstVariousPresentAndFormerDirectorsAndOfficersOfHenryScheinMember_1822" order="11.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="Locator_srt_LitigationCaseTypeDomain_1823"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PutativeShareholderDerivativeActionMember" xlink:label="Locator_hsic_PutativeShareholderDerivativeActionMember_1824"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_LitigationCaseTypeDomain_1823" xlink:to="Locator_hsic_PutativeShareholderDerivativeActionMember_1824" order="12.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="Locator_us-gaap_LossContingenciesTable_1795"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOperatingActivitiesSegmentAxis" xlink:label="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_1796"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingenciesTable_1795" xlink:to="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_1796" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOperatingActivitiesSegmentAxis" xlink:label="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_1825"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="Locator_us-gaap_SegmentOperatingActivitiesDomain_1826"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementOperatingActivitiesSegmentAxis_1825" xlink:to="Locator_us-gaap_SegmentOperatingActivitiesDomain_1826" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="Locator_us-gaap_SegmentOperatingActivitiesDomain_1827"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentContinuingOperationsMember" xlink:label="Locator_us-gaap_SegmentContinuingOperationsMember_1828"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentOperatingActivitiesDomain_1827" xlink:to="Locator_us-gaap_SegmentContinuingOperationsMember_1828" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="Locator_us-gaap_LossContingenciesTable_1797"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_1798"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LossContingenciesTable_1797" xlink:to="Locator_srt_RangeAxis_1798" order="3.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtPrivatePlacementFacilitiesNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_1949"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1950"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeAxis_1949" xlink:to="Locator_srt_RangeMember_1950" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1955"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ArithmeticAverageMember" xlink:label="Locator_srt_ArithmeticAverageMember_1956"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_1955" xlink:to="Locator_srt_ArithmeticAverageMember_1956" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1951"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember" xlink:label="Locator_srt_MinimumMember_1952"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_1951" xlink:to="Locator_srt_MinimumMember_1952" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_1953"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember" xlink:label="Locator_srt_MaximumMember_1954"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_1953" xlink:to="Locator_srt_MaximumMember_1954" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_1851"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1852"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_1851" xlink:to="Locator_us-gaap_DebtInstrumentTable_1852" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1943"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="Locator_us-gaap_DebtInstrumentAxis_1944"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1943" xlink:to="Locator_us-gaap_DebtInstrumentAxis_1944" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="Locator_us-gaap_DebtInstrumentAxis_1957"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_1958"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentAxis_1957" xlink:to="Locator_us-gaap_DebtInstrumentNameDomain_1958" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_1961"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilities2031Member" xlink:label="Locator_hsic_PrivatePlacementFacilities2031Member_1962"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_1961" xlink:to="Locator_hsic_PrivatePlacementFacilities2031Member_1962" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_1959"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilities2030Member" xlink:label="Locator_hsic_PrivatePlacementFacilities2030Member_1960"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_1959" xlink:to="Locator_hsic_PrivatePlacementFacilities2030Member_1960" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1937"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1938"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1937" xlink:to="Locator_us-gaap_DebtInstrumentLineItems_1938" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1833"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="Locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_1834"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1833" xlink:to="Locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_1834" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1835"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateIncreaseDecrease" xlink:label="Locator_us-gaap_DebtInstrumentInterestRateIncreaseDecrease_1836"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1835" xlink:to="Locator_us-gaap_DebtInstrumentInterestRateIncreaseDecrease_1836" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1837"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_IndebtednessRatioAsbtractAbstract" xlink:label="Locator_hsic_IndebtednessRatioAsbtractAbstract_1838"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1837" xlink:to="Locator_hsic_IndebtednessRatioAsbtractAbstract_1838" order="3.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_IndebtednessRatioAsbtractAbstract" xlink:label="Locator_hsic_IndebtednessRatioAsbtractAbstract_1871"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RatioOfIndebtednessToTotalCapital" xlink:label="Locator_hsic_RatioOfIndebtednessToTotalCapital_1872"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_IndebtednessRatioAsbtractAbstract_1871" xlink:to="Locator_hsic_RatioOfIndebtednessToTotalCapital_1872" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_IndebtednessRatioAsbtractAbstract" xlink:label="Locator_hsic_IndebtednessRatioAsbtractAbstract_1873"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RatioOfIndebtednessToNetCapital1" xlink:label="Locator_us-gaap_RatioOfIndebtednessToNetCapital1_1874"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_IndebtednessRatioAsbtractAbstract_1873" xlink:to="Locator_us-gaap_RatioOfIndebtednessToNetCapital1_1874" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1839"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentCovenantDescription" xlink:label="Locator_us-gaap_DebtInstrumentCovenantDescription_1840"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1839" xlink:to="Locator_us-gaap_DebtInstrumentCovenantDescription_1840" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1841"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTerm" xlink:label="Locator_us-gaap_DebtInstrumentTerm_1842"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1841" xlink:to="Locator_us-gaap_DebtInstrumentTerm_1842" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1845"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_DebtInstrumentAverageTerm" xlink:label="Locator_hsic_DebtInstrumentAverageTerm_1846"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1845" xlink:to="Locator_hsic_DebtInstrumentAverageTerm_1846" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1847"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1848"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1847" xlink:to="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1848" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1853"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionConvertedInstrumentIssuanceDateMonthAndYear" xlink:label="Locator_us-gaap_DebtConversionConvertedInstrumentIssuanceDateMonthAndYear_1854"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1853" xlink:to="Locator_us-gaap_DebtConversionConvertedInstrumentIssuanceDateMonthAndYear_1854" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1855"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionOriginalDebtTypeOfDebt" xlink:label="Locator_us-gaap_DebtConversionOriginalDebtTypeOfDebt_1856"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1855" xlink:to="Locator_us-gaap_DebtConversionOriginalDebtTypeOfDebt_1856" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1857"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionOriginalDebtAmount1" xlink:label="Locator_us-gaap_DebtConversionOriginalDebtAmount1_1858"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1857" xlink:to="Locator_us-gaap_DebtConversionOriginalDebtAmount1_1858" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1859"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionOriginalDebtInterestRateOfDebt" xlink:label="Locator_us-gaap_DebtConversionOriginalDebtInterestRateOfDebt_1860"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1859" xlink:to="Locator_us-gaap_DebtConversionOriginalDebtInterestRateOfDebt_1860" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1861"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionOriginalDebtDueDateOfDebtDayMonthAndYear" xlink:label="Locator_us-gaap_DebtConversionOriginalDebtDueDateOfDebtDayMonthAndYear_1862"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1861" xlink:to="Locator_us-gaap_DebtConversionOriginalDebtDueDateOfDebtDayMonthAndYear_1862" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1863"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionConvertedInstrumentType" xlink:label="Locator_us-gaap_DebtConversionConvertedInstrumentType_1864"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1863" xlink:to="Locator_us-gaap_DebtConversionConvertedInstrumentType_1864" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1865"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionConvertedInstrumentAmount1" xlink:label="Locator_us-gaap_DebtConversionConvertedInstrumentAmount1_1866"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1865" xlink:to="Locator_us-gaap_DebtConversionConvertedInstrumentAmount1_1866" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1867"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionConvertedInstrumentExpirationOrDueDateDayMonthAndYear" xlink:label="Locator_us-gaap_DebtConversionConvertedInstrumentExpirationOrDueDateDayMonthAndYear_1868"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1867" xlink:to="Locator_us-gaap_DebtConversionConvertedInstrumentExpirationOrDueDateDayMonthAndYear_1868" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1869"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtConversionConvertedInstrumentRate" xlink:label="Locator_us-gaap_DebtConversionConvertedInstrumentRate_1870"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NoncashInvestingAndFinancingItemsAbstract_1869" xlink:to="Locator_us-gaap_DebtConversionConvertedInstrumentRate_1870" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_1843"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentMaturityDate" xlink:label="Locator_us-gaap_DebtInstrumentMaturityDate_1844"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_1843" xlink:to="Locator_us-gaap_DebtInstrumentMaturityDate_1844" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1939"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_1940"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1939" xlink:to="Locator_us-gaap_LongtermDebtTypeAxis_1940" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_1945"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_1946"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeAxis_1945" xlink:to="Locator_us-gaap_LongtermDebtTypeDomain_1946" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_1947"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesMember" xlink:label="Locator_hsic_PrivatePlacementFacilitiesMember_1948"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeDomain_1947" xlink:to="Locator_hsic_PrivatePlacementFacilitiesMember_1948" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_1941"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_1942"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_1941" xlink:to="Locator_srt_RangeAxis_1942" order="2.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/PlansOfRestructuringRestructuringReserveRollForwardByExpenseAndSegmentDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_1975"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_1976"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringAndRelatedActivitiesAbstract_1975" xlink:to="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_1976" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_2007"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="Locator_us-gaap_RestructuringCostAndReserveLineItems_2008"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_2007" xlink:to="Locator_us-gaap_RestructuringCostAndReserveLineItems_2008" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="Locator_us-gaap_RestructuringCostAndReserveLineItems_1963"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="Locator_us-gaap_RestructuringReserveRollForward_1964"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringCostAndReserveLineItems_1963" xlink:to="Locator_us-gaap_RestructuringReserveRollForward_1964" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="Locator_us-gaap_RestructuringReserveRollForward_1969"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringSettlementAndImpairmentProvisions" xlink:label="Locator_us-gaap_RestructuringSettlementAndImpairmentProvisions_1970"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringReserveRollForward_1969" xlink:to="Locator_us-gaap_RestructuringSettlementAndImpairmentProvisions_1970" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="Locator_us-gaap_RestructuringReserveRollForward_1971"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PaymentsForRestructuringAndRestructuringReserveAccrualAdjustment" xlink:label="Locator_hsic_PaymentsForRestructuringAndRestructuringReserveAccrualAdjustment_1972"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringReserveRollForward_1971" xlink:to="Locator_hsic_PaymentsForRestructuringAndRestructuringReserveAccrualAdjustment_1972" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="Locator_us-gaap_RestructuringReserveRollForward_1967"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="Locator_us-gaap_RestructuringReserve_1968"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringReserveRollForward_1967" xlink:to="Locator_us-gaap_RestructuringReserve_1968" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="Locator_us-gaap_RestructuringReserveRollForward_1973"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="Locator_us-gaap_RestructuringReserve_1974"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringReserveRollForward_1973" xlink:to="Locator_us-gaap_RestructuringReserve_1974" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_2009"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="Locator_us-gaap_RestructuringCostAndReserveAxis_2010"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_2009" xlink:to="Locator_us-gaap_RestructuringCostAndReserveAxis_2010" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="Locator_us-gaap_RestructuringCostAndReserveAxis_2019"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="Locator_us-gaap_TypeOfRestructuringDomain_2020"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RestructuringCostAndReserveAxis_2019" xlink:to="Locator_us-gaap_TypeOfRestructuringDomain_2020" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="Locator_us-gaap_TypeOfRestructuringDomain_2021"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeSeveranceMember" xlink:label="Locator_us-gaap_EmployeeSeveranceMember_2022"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TypeOfRestructuringDomain_2021" xlink:to="Locator_us-gaap_EmployeeSeveranceMember_2022" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="Locator_us-gaap_TypeOfRestructuringDomain_2023"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FacilityClosingMember" xlink:label="Locator_us-gaap_FacilityClosingMember_2024"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TypeOfRestructuringDomain_2023" xlink:to="Locator_us-gaap_FacilityClosingMember_2024" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="Locator_us-gaap_TypeOfRestructuringDomain_2025"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="Locator_us-gaap_OtherRestructuringMember_2026"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TypeOfRestructuringDomain_2025" xlink:to="Locator_us-gaap_OtherRestructuringMember_2026" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_2011"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="Locator_us-gaap_StatementBusinessSegmentsAxis_2012"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_2011" xlink:to="Locator_us-gaap_StatementBusinessSegmentsAxis_2012" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="Locator_us-gaap_StatementBusinessSegmentsAxis_2017"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_2018"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementBusinessSegmentsAxis_2017" xlink:to="Locator_us-gaap_SegmentDomain_2018" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_2013"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_HealthcareDistributionMember" xlink:label="Locator_hsic_HealthcareDistributionMember_2014"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDomain_2013" xlink:to="Locator_hsic_HealthcareDistributionMember_2014" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_2015"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TechnologyMember" xlink:label="Locator_hsic_TechnologyMember_2016"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDomain_2015" xlink:to="Locator_hsic_TechnologyMember_2016" order="2.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/StockBasedCompensationUnvestedRestictedStockUnitsActivityDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2057"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2058"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2057" xlink:to="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2058" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2105"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2106"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2105" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2106" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2027"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2028"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2027" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2028" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2037"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_2038"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2037" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_2038" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2039"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ReversalOfGrantsInPeriodDueToCovid19Impact" xlink:label="Locator_hsic_ReversalOfGrantsInPeriodDueToCovid19Impact_2040"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2039" xlink:to="Locator_hsic_ReversalOfGrantsInPeriodDueToCovid19Impact_2040" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2041"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_2042"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2041" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_2042" order="4.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2043"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_2044"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2043" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_2044" order="5.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2035"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_2036"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2035" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_2036" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2045"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_2046"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_2045" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_2046" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2029"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2030"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2029" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2030" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2049"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_2050"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2049" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_2050" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2051"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_2052"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2051" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_2052" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2053"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_2054"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2053" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_2054" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2047"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2048"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2047" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2048" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2055"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2056"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2055" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2056" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2031"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedIntrinsicValue" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedIntrinsicValue_2032"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2031" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedIntrinsicValue_2032" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2107"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="Locator_us-gaap_AwardTypeAxis_2108"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2107" xlink:to="Locator_us-gaap_AwardTypeAxis_2108" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="Locator_us-gaap_AwardTypeAxis_2111"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2112"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AwardTypeAxis_2111" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2112" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2113"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RestrictedStockAndRestrictedStockUnitAwardsMember" xlink:label="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_2114"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2113" xlink:to="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_2114" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RestrictedStockAndRestrictedStockUnitAwardsMember" xlink:label="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_2115"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TimeBasedRestrictedStockRestrictedUnitsMember" xlink:label="Locator_hsic_TimeBasedRestrictedStockRestrictedUnitsMember_2116"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_2115" xlink:to="Locator_hsic_TimeBasedRestrictedStockRestrictedUnitsMember_2116" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_RestrictedStockAndRestrictedStockUnitAwardsMember" xlink:label="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_2117"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PerformanceBasedRestrictedStockRestrictedUnitsMember" xlink:label="Locator_hsic_PerformanceBasedRestrictedStockRestrictedUnitsMember_2118"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_RestrictedStockAndRestrictedStockUnitAwardsMember_2117" xlink:to="Locator_hsic_PerformanceBasedRestrictedStockRestrictedUnitsMember_2118" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2109"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="Locator_us-gaap_PlanNameAxis_2110"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2109" xlink:to="Locator_us-gaap_PlanNameAxis_2110" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="Locator_us-gaap_PlanNameAxis_2119"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="Locator_us-gaap_PlanNameDomain_2120"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_PlanNameAxis_2119" xlink:to="Locator_us-gaap_PlanNameDomain_2120" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="Locator_us-gaap_PlanNameDomain_2121"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_StockIncentivePlanMember" xlink:label="Locator_hsic_StockIncentivePlanMember_2122"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_PlanNameDomain_2121" xlink:to="Locator_hsic_StockIncentivePlanMember_2122" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="Locator_us-gaap_PlanNameDomain_2123"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_NonEmployeeDirectorStockIncentivePlanMember" xlink:label="Locator_hsic_NonEmployeeDirectorStockIncentivePlanMember_2124"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_PlanNameDomain_2123" xlink:to="Locator_hsic_NonEmployeeDirectorStockIncentivePlanMember_2124" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtPrivatePlacementBorrowingsDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_2145"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2146"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_2145" xlink:to="Locator_us-gaap_DebtInstrumentTable_2146" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2201"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="Locator_us-gaap_DebtInstrumentAxis_2202"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_2201" xlink:to="Locator_us-gaap_DebtInstrumentAxis_2202" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="Locator_us-gaap_DebtInstrumentAxis_2203"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2204"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentAxis_2203" xlink:to="Locator_us-gaap_DebtInstrumentNameDomain_2204" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2205"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilities2022Member" xlink:label="Locator_hsic_PrivatePlacementFacilities2022Member_2206"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2205" xlink:to="Locator_hsic_PrivatePlacementFacilities2022Member_2206" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2207"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilities2024Member" xlink:label="Locator_hsic_PrivatePlacementFacilities2024Member_2208"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2207" xlink:to="Locator_hsic_PrivatePlacementFacilities2024Member_2208" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2209"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesDecember2024Member" xlink:label="Locator_hsic_PrivatePlacementFacilitiesDecember2024Member_2210"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2209" xlink:to="Locator_hsic_PrivatePlacementFacilitiesDecember2024Member_2210" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2211"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesJune2021Member" xlink:label="Locator_hsic_PrivatePlacementFacilitiesJune2021Member_2212"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2211" xlink:to="Locator_hsic_PrivatePlacementFacilitiesJune2021Member_2212" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2213"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesJune2027Member" xlink:label="Locator_hsic_PrivatePlacementFacilitiesJune2027Member_2214"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2213" xlink:to="Locator_hsic_PrivatePlacementFacilitiesJune2027Member_2214" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2215"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesSeptember2029Member" xlink:label="Locator_hsic_PrivatePlacementFacilitiesSeptember2029Member_2216"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2215" xlink:to="Locator_hsic_PrivatePlacementFacilitiesSeptember2029Member_2216" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2217"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesJanuary2028Member" xlink:label="Locator_hsic_PrivatePlacementFacilitiesJanuary2028Member_2218"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2217" xlink:to="Locator_hsic_PrivatePlacementFacilitiesJanuary2028Member_2218" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="Locator_us-gaap_DebtInstrumentNameDomain_2219"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilities2030Member" xlink:label="Locator_hsic_PrivatePlacementFacilities2030Member_2220"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentNameDomain_2219" xlink:to="Locator_hsic_PrivatePlacementFacilities2030Member_2220" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2197"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2198"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_2197" xlink:to="Locator_us-gaap_DebtInstrumentLineItems_2198" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2125"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentIssuanceDate1" xlink:label="Locator_us-gaap_DebtInstrumentIssuanceDate1_2126"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2125" xlink:to="Locator_us-gaap_DebtInstrumentIssuanceDate1_2126" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2127"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="Locator_us-gaap_DebtInstrumentCarryingAmount_2128"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2127" xlink:to="Locator_us-gaap_DebtInstrumentCarryingAmount_2128" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2129"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredFinanceCostsGross" xlink:label="Locator_us-gaap_DeferredFinanceCostsGross_2130"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2129" xlink:to="Locator_us-gaap_DeferredFinanceCostsGross_2130" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2135"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentMaturityDate" xlink:label="Locator_us-gaap_DebtInstrumentMaturityDate_2136"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2135" xlink:to="Locator_us-gaap_DebtInstrumentMaturityDate_2136" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2137"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentFrequencyOfPeriodicPayment" xlink:label="Locator_us-gaap_DebtInstrumentFrequencyOfPeriodicPayment_2138"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2137" xlink:to="Locator_us-gaap_DebtInstrumentFrequencyOfPeriodicPayment_2138" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2139"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentPeriodicPaymentPrincipal" xlink:label="Locator_us-gaap_DebtInstrumentPeriodicPaymentPrincipal_2140"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2139" xlink:to="Locator_us-gaap_DebtInstrumentPeriodicPaymentPrincipal_2140" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2141"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentDateOfFirstRequiredPayment1" xlink:label="Locator_us-gaap_DebtInstrumentDateOfFirstRequiredPayment1_2142"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2141" xlink:to="Locator_us-gaap_DebtInstrumentDateOfFirstRequiredPayment1_2142" order="9.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2131"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities" xlink:label="Locator_hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities_2132"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2131" xlink:to="Locator_hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities_2132" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2133"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="Locator_us-gaap_DebtInstrumentInterestRateStatedPercentage_2134"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2133" xlink:to="Locator_us-gaap_DebtInstrumentInterestRateStatedPercentage_2134" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2199"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_2200"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_2199" xlink:to="Locator_us-gaap_LongtermDebtTypeAxis_2200" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_2221"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_2222"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeAxis_2221" xlink:to="Locator_us-gaap_LongtermDebtTypeDomain_2222" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_2223"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesMember" xlink:label="Locator_hsic_PrivatePlacementFacilitiesMember_2224"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeDomain_2223" xlink:to="Locator_hsic_PrivatePlacementFacilitiesMember_2224" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtLongtermDebtDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_2297"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_2298"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeAxis_2297" xlink:to="Locator_srt_RangeMember_2298" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_2299"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember" xlink:label="Locator_srt_MinimumMember_2300"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_2299" xlink:to="Locator_srt_MinimumMember_2300" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_2301"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember" xlink:label="Locator_srt_MaximumMember_2302"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_2301" xlink:to="Locator_srt_MaximumMember_2302" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_2239"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2240"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_2239" xlink:to="Locator_us-gaap_DebtInstrumentTable_2240" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2281"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2282"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_2281" xlink:to="Locator_us-gaap_DebtInstrumentLineItems_2282" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2225"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities" xlink:label="Locator_hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities_2226"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2225" xlink:to="Locator_hsic_LongTermDebtAndFinanceLeaseObligationsIncludingCurrentMaturities_2226" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2227"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligationsCurrent" xlink:label="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligationsCurrent_2228"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2227" xlink:to="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligationsCurrent_2228" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2229"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligations" xlink:label="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligations_2230"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2229" xlink:to="Locator_us-gaap_LongTermDebtAndCapitalLeaseObligations_2230" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2231"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="Locator_us-gaap_FinanceLeaseLiability_2232"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2231" xlink:to="Locator_us-gaap_FinanceLeaseLiability_2232" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2233"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="Locator_us-gaap_DebtInstrumentInterestRateStatedPercentage_2234"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2233" xlink:to="Locator_us-gaap_DebtInstrumentInterestRateStatedPercentage_2234" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="Locator_us-gaap_DebtInstrumentLineItems_2235"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentMaturityDateDescription" xlink:label="Locator_us-gaap_DebtInstrumentMaturityDateDescription_2236"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentLineItems_2235" xlink:to="Locator_us-gaap_DebtInstrumentMaturityDateDescription_2236" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2283"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_2284"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_2283" xlink:to="Locator_us-gaap_LongtermDebtTypeAxis_2284" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="Locator_us-gaap_LongtermDebtTypeAxis_2287"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_2288"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeAxis_2287" xlink:to="Locator_us-gaap_LongtermDebtTypeDomain_2288" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_2289"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PrivatePlacementFacilitiesMember" xlink:label="Locator_hsic_PrivatePlacementFacilitiesMember_2290"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeDomain_2289" xlink:to="Locator_hsic_PrivatePlacementFacilitiesMember_2290" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_2291"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_USTradeAccountsReceivableSecuritizationMember" xlink:label="Locator_hsic_USTradeAccountsReceivableSecuritizationMember_2292"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeDomain_2291" xlink:to="Locator_hsic_USTradeAccountsReceivableSecuritizationMember_2292" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_2293"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesPayableOtherPayablesMember" xlink:label="Locator_us-gaap_NotesPayableOtherPayablesMember_2294"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeDomain_2293" xlink:to="Locator_us-gaap_NotesPayableOtherPayablesMember_2294" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="Locator_us-gaap_LongtermDebtTypeDomain_2295"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LoansPayableMember" xlink:label="Locator_us-gaap_LoansPayableMember_2296"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LongtermDebtTypeDomain_2295" xlink:to="Locator_us-gaap_LoansPayableMember_2296" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="Locator_us-gaap_DebtInstrumentTable_2285"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_2286"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtInstrumentTable_2285" xlink:to="Locator_srt_RangeAxis_2286" order="2.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/BasisOfPresentationNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="Locator_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_2317"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_2318"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_2317" xlink:to="Locator_us-gaap_StatementTable_2318" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_2355"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_2356"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_2355" xlink:to="Locator_us-gaap_StatementLineItems_2356" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_2303"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableInterestEntityTermsOfArrangements" xlink:label="Locator_us-gaap_VariableInterestEntityTermsOfArrangements_2304"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_2303" xlink:to="Locator_us-gaap_VariableInterestEntityTermsOfArrangements_2304" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_2305"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableInterestEntityVIEPurposeOfVIE" xlink:label="Locator_us-gaap_VariableInterestEntityVIEPurposeOfVIE_2306"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_2305" xlink:to="Locator_us-gaap_VariableInterestEntityVIEPurposeOfVIE_2306" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_2307"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableInterestEntityExtentOfOrLackOfRecourse" xlink:label="Locator_us-gaap_VariableInterestEntityExtentOfOrLackOfRecourse_2308"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_2307" xlink:to="Locator_us-gaap_VariableInterestEntityExtentOfOrLackOfRecourse_2308" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_2309"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableInterestEntityCarryingAmountAssetsAndLiabilitiesQualitativeInformation" xlink:label="Locator_us-gaap_VariableInterestEntityCarryingAmountAssetsAndLiabilitiesQualitativeInformation_2310"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_2309" xlink:to="Locator_us-gaap_VariableInterestEntityCarryingAmountAssetsAndLiabilitiesQualitativeInformation_2310" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_2311"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableInterestEntityVIEActivitiesOfVIE" xlink:label="Locator_us-gaap_VariableInterestEntityVIEActivitiesOfVIE_2312"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_2311" xlink:to="Locator_us-gaap_VariableInterestEntityVIEActivitiesOfVIE_2312" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems" xlink:label="Locator_us-gaap_StatementLineItems_2313"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationName" xlink:label="Locator_us-gaap_DiscontinuedOperationName_2314"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementLineItems_2313" xlink:to="Locator_us-gaap_DiscontinuedOperationName_2314" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_2357"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesAxis" xlink:label="Locator_srt_ConsolidatedEntitiesAxis_2358"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_2357" xlink:to="Locator_srt_ConsolidatedEntitiesAxis_2358" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesAxis" xlink:label="Locator_srt_ConsolidatedEntitiesAxis_2363"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesDomain" xlink:label="Locator_srt_ConsolidatedEntitiesDomain_2364"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidatedEntitiesAxis_2363" xlink:to="Locator_srt_ConsolidatedEntitiesDomain_2364" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidatedEntitiesDomain" xlink:label="Locator_srt_ConsolidatedEntitiesDomain_2367"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableInterestEntityPrimaryBeneficiaryMember" xlink:label="Locator_us-gaap_VariableInterestEntityPrimaryBeneficiaryMember_2368"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidatedEntitiesDomain_2367" xlink:to="Locator_us-gaap_VariableInterestEntityPrimaryBeneficiaryMember_2368" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_2359"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RecourseStatusAxis" xlink:label="Locator_us-gaap_RecourseStatusAxis_2360"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_2359" xlink:to="Locator_us-gaap_RecourseStatusAxis_2360" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RecourseStatusAxis" xlink:label="Locator_us-gaap_RecourseStatusAxis_2365"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RecourseStatusDomain" xlink:label="Locator_us-gaap_RecourseStatusDomain_2366"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RecourseStatusAxis_2365" xlink:to="Locator_us-gaap_RecourseStatusDomain_2366" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RecourseStatusDomain" xlink:label="Locator_us-gaap_RecourseStatusDomain_2369"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RecourseMember" xlink:label="Locator_us-gaap_RecourseMember_2370"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RecourseStatusDomain_2369" xlink:to="Locator_us-gaap_RecourseMember_2370" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable" xlink:label="Locator_us-gaap_StatementTable_2361"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PledgedStatusAxis" xlink:label="Locator_us-gaap_PledgedStatusAxis_2362"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementTable_2361" xlink:to="Locator_us-gaap_PledgedStatusAxis_2362" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PledgedStatusAxis" xlink:label="Locator_us-gaap_PledgedStatusAxis_2371"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PledgedStatusDomain" xlink:label="Locator_us-gaap_PledgedStatusDomain_2372"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_PledgedStatusAxis_2371" xlink:to="Locator_us-gaap_PledgedStatusDomain_2372" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PledgedStatusDomain" xlink:label="Locator_us-gaap_PledgedStatusDomain_2373"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetPledgedAsCollateralMember" xlink:label="Locator_us-gaap_AssetPledgedAsCollateralMember_2374"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_PledgedStatusDomain_2373" xlink:to="Locator_us-gaap_AssetPledgedAsCollateralMember_2374" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandards">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2375"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_2376"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2375" xlink:to="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_2376" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RevenueFromContractsWithCustomers">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2377"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerTextBlock_2378"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2377" xlink:to="Locator_us-gaap_RevenueFromContractWithCustomerTextBlock_2378" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RevenueFromContractsWithCustomersDisaggregationOfRevenueDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="Locator_us-gaap_StatementBusinessSegmentsAxis_2447"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_2448"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementBusinessSegmentsAxis_2447" xlink:to="Locator_us-gaap_SegmentDomain_2448" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_2435"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_HealthcareDistributionMember" xlink:label="Locator_hsic_HealthcareDistributionMember_2436"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDomain_2435" xlink:to="Locator_hsic_HealthcareDistributionMember_2436" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain" xlink:label="Locator_us-gaap_SegmentDomain_2437"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_TechnologyMember" xlink:label="Locator_hsic_TechnologyMember_2438"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDomain_2437" xlink:to="Locator_hsic_TechnologyMember_2438" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2433"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTable_2434"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2433" xlink:to="Locator_us-gaap_DisaggregationOfRevenueTable_2434" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTable_2443"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems" xlink:label="Locator_us-gaap_DisaggregationOfRevenueLineItems_2444"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueTable_2443" xlink:to="Locator_us-gaap_DisaggregationOfRevenueLineItems_2444" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems" xlink:label="Locator_us-gaap_DisaggregationOfRevenueLineItems_2379"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueAbstract" xlink:label="Locator_us-gaap_DisaggregationOfRevenueAbstract_2380"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueLineItems_2379" xlink:to="Locator_us-gaap_DisaggregationOfRevenueAbstract_2380" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueAbstract" xlink:label="Locator_us-gaap_DisaggregationOfRevenueAbstract_2381"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_2382"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueAbstract_2381" xlink:to="Locator_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_2382" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTable_2445"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="Locator_us-gaap_StatementBusinessSegmentsAxis_2446"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueTable_2445" xlink:to="Locator_us-gaap_StatementBusinessSegmentsAxis_2446" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTable_2449"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsAxis" xlink:label="Locator_us-gaap_SubsegmentsAxis_2450"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueTable_2449" xlink:to="Locator_us-gaap_SubsegmentsAxis_2450" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsAxis" xlink:label="Locator_us-gaap_SubsegmentsAxis_2451"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsDomain" xlink:label="Locator_us-gaap_SubsegmentsDomain_2452"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsAxis_2451" xlink:to="Locator_us-gaap_SubsegmentsDomain_2452" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsDomain" xlink:label="Locator_us-gaap_SubsegmentsDomain_2453"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_DentalMember" xlink:label="Locator_hsic_DentalMember_2454"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsDomain_2453" xlink:to="Locator_hsic_DentalMember_2454" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsDomain" xlink:label="Locator_us-gaap_SubsegmentsDomain_2455"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_MedicalMember" xlink:label="Locator_hsic_MedicalMember_2456"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsDomain_2455" xlink:to="Locator_hsic_MedicalMember_2456" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTable_2457"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementGeographicalAxis" xlink:label="Locator_srt_StatementGeographicalAxis_2458"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueTable_2457" xlink:to="Locator_srt_StatementGeographicalAxis_2458" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementGeographicalAxis" xlink:label="Locator_srt_StatementGeographicalAxis_2459"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="Locator_srt_SegmentGeographicalDomain_2460"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_StatementGeographicalAxis_2459" xlink:to="Locator_srt_SegmentGeographicalDomain_2460" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="Locator_srt_SegmentGeographicalDomain_2439"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_NorthAmericaMember" xlink:label="Locator_srt_NorthAmericaMember_2440"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_SegmentGeographicalDomain_2439" xlink:to="Locator_srt_NorthAmericaMember_2440" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="Locator_srt_SegmentGeographicalDomain_2441"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_InternationalMember" xlink:label="Locator_hsic_InternationalMember_2442"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_SegmentGeographicalDomain_2441" xlink:to="Locator_hsic_InternationalMember_2442" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTable_2461"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="Locator_srt_ConsolidationItemsAxis_2462"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueTable_2461" xlink:to="Locator_srt_ConsolidationItemsAxis_2462" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="Locator_srt_ConsolidationItemsAxis_2463"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="Locator_srt_ConsolidationItemsDomain_2464"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidationItemsAxis_2463" xlink:to="Locator_srt_ConsolidationItemsDomain_2464" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="Locator_srt_ConsolidationItemsDomain_2465"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="Locator_us-gaap_OperatingSegmentsMember_2466"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidationItemsDomain_2465" xlink:to="Locator_us-gaap_OperatingSegmentsMember_2466" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="Locator_srt_ConsolidationItemsDomain_2467"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="Locator_us-gaap_CorporateNonSegmentMember_2468"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ConsolidationItemsDomain_2467" xlink:to="Locator_us-gaap_CorporateNonSegmentMember_2468" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTable_2469"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsAxis" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_2470"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisaggregationOfRevenueTable_2469" xlink:to="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_2470" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsAxis" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_2471"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsDomain" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_2472"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsConsolidationItemsAxis_2471" xlink:to="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_2472" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsegmentsConsolidationItemsDomain" xlink:label="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_2473"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReportableSubsegmentsMember" xlink:label="Locator_us-gaap_ReportableSubsegmentsMember_2474"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SubsegmentsConsolidationItemsDomain_2473" xlink:to="Locator_us-gaap_ReportableSubsegmentsMember_2474" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RevenueFromContractsWithCustomersTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2475"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:label="Locator_us-gaap_DisaggregationOfRevenueTableTextBlock_2476"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2475" xlink:to="Locator_us-gaap_DisaggregationOfRevenueTableTextBlock_2476" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandardsPolicies">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2477"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="Locator_us-gaap_ConsolidationPolicyTextBlock_2478"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2477" xlink:to="Locator_us-gaap_ConsolidationPolicyTextBlock_2478" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2479"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsolidationVariableInterestEntityPolicy" xlink:label="Locator_us-gaap_ConsolidationVariableInterestEntityPolicy_2480"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2479" xlink:to="Locator_us-gaap_ConsolidationVariableInterestEntityPolicy_2480" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2481"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="Locator_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_2482"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2481" xlink:to="Locator_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_2482" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2483"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="Locator_us-gaap_IncomeTaxPolicyTextBlock_2484"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2483" xlink:to="Locator_us-gaap_IncomeTaxPolicyTextBlock_2484" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2485"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="Locator_us-gaap_UseOfEstimates_2486"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2485" xlink:to="Locator_us-gaap_UseOfEstimates_2486" order="5.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RevenueFromContractsWithCustomersContractBalancesDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2487"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent" xlink:label="Locator_us-gaap_ContractWithCustomerLiabilityCurrent_2488"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2487" xlink:to="Locator_us-gaap_ContractWithCustomerLiabilityCurrent_2488" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2489"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent" xlink:label="Locator_us-gaap_ContractWithCustomerLiabilityNoncurrent_2490"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2489" xlink:to="Locator_us-gaap_ContractWithCustomerLiabilityNoncurrent_2490" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2491"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerLiabilityRevenueRecognized" xlink:label="Locator_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_2492"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RevenueFromContractWithCustomerAbstract_2491" xlink:to="Locator_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_2492" order="3.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CriticalAccountingPoliciesAccountingPronouncementsAdoptedAndRecentlyIssuedAccountingStandardsNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract" xlink:label="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2503"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2504"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesAbstract_2503" xlink:to="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2504" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2541"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2542"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2541" xlink:to="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2542" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2493"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdopted" xlink:label="Locator_us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdopted_2494"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2493" xlink:to="Locator_us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdopted_2494" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2495"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementOrChangeInAccountingPrinciplePriorPeriodNotRestated" xlink:label="Locator_us-gaap_NewAccountingPronouncementOrChangeInAccountingPrinciplePriorPeriodNotRestated_2496"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2495" xlink:to="Locator_us-gaap_NewAccountingPronouncementOrChangeInAccountingPrinciplePriorPeriodNotRestated_2496" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2497"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateTransitionOptionElectedExtensibleList" xlink:label="Locator_us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateTransitionOptionElectedExtensibleList_2498"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2497" xlink:to="Locator_us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateTransitionOptionElectedExtensibleList_2498" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2499"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdoptionDate" xlink:label="Locator_us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdoptionDate_2500"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2499" xlink:to="Locator_us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdoptionDate_2500" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2543"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="Locator_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_2544"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2543" xlink:to="Locator_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_2544" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="Locator_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_2549"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="Locator_us-gaap_TypeOfAdoptionMember_2550"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_2549" xlink:to="Locator_us-gaap_TypeOfAdoptionMember_2550" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="Locator_us-gaap_TypeOfAdoptionMember_2551"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentsForNewAccountingPronouncementMember" xlink:label="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2552"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_TypeOfAdoptionMember_2551" xlink:to="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2552" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentsForNewAccountingPronouncementMember" xlink:label="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2563"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingStandardsUpdate201704Member" xlink:label="Locator_us-gaap_AccountingStandardsUpdate201704Member_2564"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2563" xlink:to="Locator_us-gaap_AccountingStandardsUpdate201704Member_2564" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentsForNewAccountingPronouncementMember" xlink:label="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2565"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingStandardsUpdate201613Member" xlink:label="Locator_us-gaap_AccountingStandardsUpdate201613Member_2566"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2565" xlink:to="Locator_us-gaap_AccountingStandardsUpdate201613Member_2566" order="2.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AdjustmentsForNewAccountingPronouncementMember" xlink:label="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2567"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingStandardsUpdate201912Member" xlink:label="Locator_us-gaap_AccountingStandardsUpdate201912Member_2568"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_AdjustmentsForNewAccountingPronouncementMember_2567" xlink:to="Locator_us-gaap_AccountingStandardsUpdate201912Member_2568" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2545"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="Locator_us-gaap_StatementEquityComponentsAxis_2546"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2545" xlink:to="Locator_us-gaap_StatementEquityComponentsAxis_2546" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="Locator_us-gaap_StatementEquityComponentsAxis_2553"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="Locator_us-gaap_EquityComponentDomain_2554"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_StatementEquityComponentsAxis_2553" xlink:to="Locator_us-gaap_EquityComponentDomain_2554" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="Locator_us-gaap_EquityComponentDomain_2555"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember" xlink:label="Locator_us-gaap_ParentMember_2556"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_EquityComponentDomain_2555" xlink:to="Locator_us-gaap_ParentMember_2556" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember" xlink:label="Locator_us-gaap_ParentMember_2557"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="Locator_us-gaap_RetainedEarningsMember_2558"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ParentMember_2557" xlink:to="Locator_us-gaap_RetainedEarningsMember_2558" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2547"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_2548"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_2547" xlink:to="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_2548" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_2559"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_2560"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_CumulativeEffectPeriodOfAdoptionAxis_2559" xlink:to="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_2560" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_2561"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember" xlink:label="Locator_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_2562"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_CumulativeEffectPeriodOfAdoptionDomain_2561" xlink:to="Locator_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_2562" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DiscontinuedOperationsSummarizedFinancialInformationForOurDiscontinuedOperationsDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_2569"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationRevenue" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationRevenue_2570"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_2569" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationRevenue_2570" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_2571"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationGrossProfitLoss" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationGrossProfitLoss_2572"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_2571" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationGrossProfitLoss_2572" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_2573"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_2574"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_2573" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_2574" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_2575"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation" xlink:label="Locator_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_2576"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementAbstract_2575" xlink:to="Locator_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_2576" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDiscontinuedOperationsMember" xlink:label="Locator_us-gaap_SegmentDiscontinuedOperationsMember_2755"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_2756"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SegmentDiscontinuedOperationsMember_2755" xlink:to="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_2756" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_2757"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AnimalHealthMember" xlink:label="Locator_hsic_AnimalHealthMember_2758"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_2757" xlink:to="Locator_hsic_AnimalHealthMember_2758" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="Locator_us-gaap_DisposalGroupClassificationAxis_2759"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="Locator_us-gaap_DisposalGroupClassificationDomain_2760"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupClassificationAxis_2759" xlink:to="Locator_us-gaap_DisposalGroupClassificationDomain_2760" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="Locator_us-gaap_DisposalGroupClassificationDomain_2761"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDiscontinuedOperationsMember" xlink:label="Locator_us-gaap_SegmentDiscontinuedOperationsMember_2762"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupClassificationDomain_2761" xlink:to="Locator_us-gaap_SegmentDiscontinuedOperationsMember_2762" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="Locator_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_2627"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2628"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_2627" xlink:to="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2628" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2753"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="Locator_us-gaap_DisposalGroupClassificationAxis_2754"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2753" xlink:to="Locator_us-gaap_DisposalGroupClassificationAxis_2754" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2751"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2752"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2751" xlink:to="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2752" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2577"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="Locator_us-gaap_IncomeStatementAbstract_2578"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2577" xlink:to="Locator_us-gaap_IncomeStatementAbstract_2578" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2579"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract_2580"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2579" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract_2580" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract_2583"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2584"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract_2583" xlink:to="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2584" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2587"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_2588"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2587" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_2588" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2589"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet_2590"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2589" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet_2590" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2591"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent_2592"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2591" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent_2592" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2593"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationPrepaidAndOtherAssetsCurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationPrepaidAndOtherAssetsCurrent_2594"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2593" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationPrepaidAndOtherAssetsCurrent_2594" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2595"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_2596"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2595" xlink:to="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_2596" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2597"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent_2598"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2597" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent_2598" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2599"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationGoodwillNoncurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationGoodwillNoncurrent_2600"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2599" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationGoodwillNoncurrent_2600" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2601"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationIntangibleAssetsNoncurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationIntangibleAssetsNoncurrent_2602"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2601" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationIntangibleAssetsNoncurrent_2602" order="8.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2603"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_2604"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2603" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_2604" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2605"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_2606"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationAbstract_2605" xlink:to="Locator_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_2606" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract_2585"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2586"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationBalanceSheetDisclosuresAbstract_2585" xlink:to="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2586" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2607"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableCurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableCurrent_2608"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2607" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableCurrent_2608" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2609"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2610"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2609" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2610" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2621"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccruedLiabilitiesCurrent" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccruedLiabilitiesCurrent_2622"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2621" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccruedLiabilitiesCurrent_2622" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2623"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccruedIncomeTaxesPayable" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccruedIncomeTaxesPayable_2624"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2623" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccruedIncomeTaxesPayable_2624" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2625"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentLiabilities" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentLiabilities_2626"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrentAbstract_2625" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentLiabilities_2626" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2611"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_2612"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2611" xlink:to="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_2612" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2613"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilities" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilities_2614"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2613" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilities_2614" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2615"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities" xlink:label="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_2616"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2615" xlink:to="Locator_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_2616" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2617"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_2618"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2617" xlink:to="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_2618" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2619"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_2620"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationAbstract_2619" xlink:to="Locator_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_2620" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DiscontinuedOperationsTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="Locator_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_2763"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock" xlink:label="Locator_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_2764"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_2763" xlink:to="Locator_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_2764" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/Leases">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2765"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_LeaseDisclosureTextBlock" xlink:label="Locator_hsic_LeaseDisclosureTextBlock_2766"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2765" xlink:to="Locator_hsic_LeaseDisclosureTextBlock_2766" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LeasesTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2767"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_SupplementalLeaseInformationTableTextBlock" xlink:label="Locator_hsic_SupplementalLeaseInformationTableTextBlock_2768"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2767" xlink:to="Locator_hsic_SupplementalLeaseInformationTableTextBlock_2768" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2769"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_2770"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2769" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_2770" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2771"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock_2772"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2771" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock_2772" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LeasesComponentsOfLeaseExpenseDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2773"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseCost" xlink:label="Locator_us-gaap_OperatingLeaseCost_2774"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2773" xlink:to="Locator_us-gaap_OperatingLeaseCost_2774" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2775"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2776"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2775" xlink:to="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2776" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2779"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAssetAmortization" xlink:label="Locator_us-gaap_FinanceLeaseRightOfUseAssetAmortization_2780"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2779" xlink:to="Locator_us-gaap_FinanceLeaseRightOfUseAssetAmortization_2780" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2781"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseInterestExpense" xlink:label="Locator_us-gaap_FinanceLeaseInterestExpense_2782"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2781" xlink:to="Locator_us-gaap_FinanceLeaseInterestExpense_2782" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2783"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_FinanceLeaseCost" xlink:label="Locator_hsic_FinanceLeaseCost_2784"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_2783" xlink:to="Locator_hsic_FinanceLeaseCost_2784" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2777"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionTable_2778"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2777" xlink:to="Locator_us-gaap_LesseeLeaseDescriptionTable_2778" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionTable_2803"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="Locator_us-gaap_IncomeStatementLocationAxis_2804"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionTable_2803" xlink:to="Locator_us-gaap_IncomeStatementLocationAxis_2804" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="Locator_us-gaap_IncomeStatementLocationAxis_2805"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="Locator_us-gaap_IncomeStatementLocationDomain_2806"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementLocationAxis_2805" xlink:to="Locator_us-gaap_IncomeStatementLocationDomain_2806" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="Locator_us-gaap_IncomeStatementLocationDomain_2807"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringChargesMember" xlink:label="Locator_us-gaap_RestructuringChargesMember_2808"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementLocationDomain_2807" xlink:to="Locator_us-gaap_RestructuringChargesMember_2808" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionTable_2801"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_2802"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionTable_2801" xlink:to="Locator_us-gaap_LesseeLeaseDescriptionLineItems_2802" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_2785"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_OperatingLeaseRightOfUseAssetAmortizationExpenseIncludingOperatingLeaseCredit" xlink:label="Locator_hsic_OperatingLeaseRightOfUseAssetAmortizationExpenseIncludingOperatingLeaseCredit_2786"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_2785" xlink:to="Locator_hsic_OperatingLeaseRightOfUseAssetAmortizationExpenseIncludingOperatingLeaseCredit_2786" order="1.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DiscontinuedOperationsNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="Locator_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_2819"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2820"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_2819" xlink:to="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2820" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2849"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2850"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2849" xlink:to="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2850" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2809"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MinorityInterestOwnershipPercentageByParent" xlink:label="Locator_us-gaap_MinorityInterestOwnershipPercentageByParent_2810"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2809" xlink:to="Locator_us-gaap_MinorityInterestOwnershipPercentageByParent_2810" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2811"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PeriodCoveredByAgreement" xlink:label="Locator_hsic_PeriodCoveredByAgreement_2812"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2811" xlink:to="Locator_hsic_PeriodCoveredByAgreement_2812" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2813"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationName" xlink:label="Locator_us-gaap_DiscontinuedOperationName_2814"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2813" xlink:to="Locator_us-gaap_DiscontinuedOperationName_2814" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2815"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeconsolidationNatureOfContinuingInvolvementDescription" xlink:label="Locator_us-gaap_DeconsolidationNatureOfContinuingInvolvementDescription_2816"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_2815" xlink:to="Locator_us-gaap_DeconsolidationNatureOfContinuingInvolvementDescription_2816" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2851"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_OwnershipAxis" xlink:label="Locator_srt_OwnershipAxis_2852"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2851" xlink:to="Locator_srt_OwnershipAxis_2852" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_OwnershipAxis" xlink:label="Locator_srt_OwnershipAxis_2855"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_OwnershipDomain" xlink:label="Locator_srt_OwnershipDomain_2856"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_OwnershipAxis_2855" xlink:to="Locator_srt_OwnershipDomain_2856" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_OwnershipDomain" xlink:label="Locator_srt_OwnershipDomain_2857"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_CovetrusIncMember" xlink:label="Locator_hsic_CovetrusIncMember_2858"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_OwnershipDomain_2857" xlink:to="Locator_hsic_CovetrusIncMember_2858" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2853"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LegalEntityAxis" xlink:label="Locator_dei_LegalEntityAxis_2854"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_2853" xlink:to="Locator_dei_LegalEntityAxis_2854" order="2.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LegalEntityAxis" xlink:label="Locator_dei_LegalEntityAxis_2859"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityDomain" xlink:label="Locator_dei_EntityDomain_2860"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_LegalEntityAxis_2859" xlink:to="Locator_dei_EntityDomain_2860" order="1.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityDomain" xlink:label="Locator_dei_EntityDomain_2861"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_HenryScheinStockholdersAndTheShareSaleInvestorsMember" xlink:label="Locator_hsic_HenryScheinStockholdersAndTheShareSaleInvestorsMember_2862"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_EntityDomain_2861" xlink:to="Locator_hsic_HenryScheinStockholdersAndTheShareSaleInvestorsMember_2862" order="1.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityDomain" xlink:label="Locator_dei_EntityDomain_2863"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_VetsFirstCorpMember" xlink:label="Locator_hsic_VetsFirstCorpMember_2864"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_EntityDomain_2863" xlink:to="Locator_hsic_VetsFirstCorpMember_2864" order="2.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LeasesMaturitiesOfLeaseLiabilitiesDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2865"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2866"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2865" xlink:to="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2866" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2869"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_2870"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2869" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_2870" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2871"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_2872"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2871" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_2872" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2873"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_2874"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2873" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_2874" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2875"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_2876"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2875" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_2876" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2877"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_2878"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2877" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_2878" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2879"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_2880"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2879" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_2880" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2881"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_2882"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2881" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_2882" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2883"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_2884"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2883" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_2884" order="8.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2885"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="Locator_us-gaap_OperatingLeaseLiability_2886"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_2885" xlink:to="Locator_us-gaap_OperatingLeaseLiability_2886" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2867"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2868"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2867" xlink:to="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2868" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2887"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_2888"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2887" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_2888" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2889"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_2890"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2889" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_2890" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2891"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_2892"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2891" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_2892" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2893"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_2894"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2893" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_2894" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2895"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_2896"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2895" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_2896" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2897"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueAfterYearFive" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueAfterYearFive_2898"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2897" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDueAfterYearFive_2898" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2899"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDue_2900"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2899" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDue_2900" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2901"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_2902"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2901" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_2902" order="8.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2903"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="Locator_us-gaap_FinanceLeaseLiability_2904"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_2903" xlink:to="Locator_us-gaap_FinanceLeaseLiability_2904" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LeasesPresentValueOfLeaseLiabilitiesDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2929"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2930"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2929" xlink:to="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2930" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2933"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_2934"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2933" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_2934" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2935"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_2936"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2935" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_2936" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2937"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="Locator_us-gaap_OperatingLeaseLiability_2938"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_OperatingLeaseLiabilitiesGrossDifferenceAmountAbstract_2937" xlink:to="Locator_us-gaap_OperatingLeaseLiability_2938" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2931"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2932"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2931" xlink:to="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2932" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2939"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDue_2940"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2939" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityPaymentsDue_2940" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2941"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_2942"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2941" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_2942" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract" xlink:label="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2943"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="Locator_us-gaap_FinanceLeaseLiability_2944"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilitiesGrossDifferenceAmountAbstract_2943" xlink:to="Locator_us-gaap_FinanceLeaseLiability_2944" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtBankCreditLinesDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_2957"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="Locator_us-gaap_LineOfCreditFacilityTable_2958"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_2957" xlink:to="Locator_us-gaap_LineOfCreditFacilityTable_2958" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="Locator_us-gaap_LineOfCreditFacilityTable_2973"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_2974"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityTable_2973" xlink:to="Locator_us-gaap_LineOfCreditFacilityLineItems_2974" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="Locator_us-gaap_LineOfCreditFacilityLineItems_2953"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermBorrowings" xlink:label="Locator_us-gaap_ShortTermBorrowings_2954"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityLineItems_2953" xlink:to="Locator_us-gaap_ShortTermBorrowings_2954" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="Locator_us-gaap_LineOfCreditFacilityTable_2975"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="Locator_us-gaap_CreditFacilityAxis_2976"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditFacilityTable_2975" xlink:to="Locator_us-gaap_CreditFacilityAxis_2976" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="Locator_us-gaap_CreditFacilityAxis_2977"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="Locator_us-gaap_CreditFacilityDomain_2978"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_CreditFacilityAxis_2977" xlink:to="Locator_us-gaap_CreditFacilityDomain_2978" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="Locator_us-gaap_CreditFacilityDomain_2979"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_2980"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_CreditFacilityDomain_2979" xlink:to="Locator_us-gaap_LineOfCreditMember_2980" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_2981"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="Locator_us-gaap_RevolvingCreditFacilityMember_2982"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditMember_2981" xlink:to="Locator_us-gaap_RevolvingCreditFacilityMember_2982" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_2983"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_ThreeHundredSixtyFourDayCreditAgreementMember" xlink:label="Locator_hsic_ThreeHundredSixtyFourDayCreditAgreementMember_2984"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditMember_2983" xlink:to="Locator_hsic_ThreeHundredSixtyFourDayCreditAgreementMember_2984" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="Locator_us-gaap_LineOfCreditMember_2985"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_VariousBankCreditLinesMember" xlink:label="Locator_hsic_VariousBankCreditLinesMember_2986"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LineOfCreditMember_2985" xlink:to="Locator_hsic_VariousBankCreditLinesMember_2986" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LeasesSupplementalCashFlowInformationDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2987"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2988"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2987" xlink:to="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2988" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2991"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeasePayments" xlink:label="Locator_us-gaap_OperatingLeasePayments_2992"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2991" xlink:to="Locator_us-gaap_OperatingLeasePayments_2992" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2993"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseInterestPaymentOnLiability" xlink:label="Locator_us-gaap_FinanceLeaseInterestPaymentOnLiability_2994"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2993" xlink:to="Locator_us-gaap_FinanceLeaseInterestPaymentOnLiability_2994" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2995"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeasePrincipalPayments" xlink:label="Locator_us-gaap_FinanceLeasePrincipalPayments_2996"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_SupplementalCashFlowInformationAbstract_2995" xlink:to="Locator_us-gaap_FinanceLeasePrincipalPayments_2996" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_2989"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeDisclosureAbstract" xlink:label="Locator_us-gaap_LesseeDisclosureAbstract_2990"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_2989" xlink:to="Locator_us-gaap_LesseeDisclosureAbstract_2990" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeDisclosureAbstract" xlink:label="Locator_us-gaap_LesseeDisclosureAbstract_2997"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability" xlink:label="Locator_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_2998"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeDisclosureAbstract_2997" xlink:to="Locator_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_2998" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeDisclosureAbstract" xlink:label="Locator_us-gaap_LesseeDisclosureAbstract_2999"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability" xlink:label="Locator_us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability_3000"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeDisclosureAbstract_2999" xlink:to="Locator_us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability_3000" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LeasesSupplementalBalanceSheetInformationDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3023"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization" xlink:label="Locator_us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization_3024"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3023" xlink:to="Locator_us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization_3024" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3025"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization" xlink:label="Locator_us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization_3026"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3025" xlink:to="Locator_us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization_3026" order="2.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3027"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAsset" xlink:label="Locator_us-gaap_FinanceLeaseRightOfUseAsset_3028"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3027" xlink:to="Locator_us-gaap_FinanceLeaseRightOfUseAsset_3028" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAsset" xlink:label="Locator_us-gaap_FinanceLeaseRightOfUseAsset_3035"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList" xlink:label="Locator_us-gaap_FinanceLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_3036"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseRightOfUseAsset_3035" xlink:to="Locator_us-gaap_FinanceLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_3036" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3029"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityCurrent" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityCurrent_3030"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3029" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityCurrent_3030" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityCurrent" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityCurrent_3041"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList_3042"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilityCurrent_3041" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList_3042" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3031"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityNoncurrent_3032"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3031" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityNoncurrent_3032" order="5.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityNoncurrent_3043"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList" xlink:label="Locator_us-gaap_FinanceLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList_3044"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_FinanceLeaseLiabilityNoncurrent_3043" xlink:to="Locator_us-gaap_FinanceLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList_3044" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3033"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="Locator_us-gaap_FinanceLeaseLiability_3034"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3033" xlink:to="Locator_us-gaap_FinanceLeaseLiability_3034" order="6.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_3001"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAndLiabilitiesLesseeAbstract" xlink:label="Locator_us-gaap_AssetsAndLiabilitiesLesseeAbstract_3002"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_3001" xlink:to="Locator_us-gaap_AssetsAndLiabilitiesLesseeAbstract_3002" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAndLiabilitiesLesseeAbstract" xlink:label="Locator_us-gaap_AssetsAndLiabilitiesLesseeAbstract_3011"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3012"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAndLiabilitiesLesseeAbstract_3011" xlink:to="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3012" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3015"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="Locator_us-gaap_OperatingLeaseRightOfUseAsset_3016"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3015" xlink:to="Locator_us-gaap_OperatingLeaseRightOfUseAsset_3016" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3017"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="Locator_us-gaap_OperatingLeaseLiabilityCurrent_3018"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3017" xlink:to="Locator_us-gaap_OperatingLeaseLiabilityCurrent_3018" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3019"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="Locator_us-gaap_OperatingLeaseLiabilityNoncurrent_3020"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3019" xlink:to="Locator_us-gaap_OperatingLeaseLiabilityNoncurrent_3020" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3021"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="Locator_us-gaap_OperatingLeaseLiability_3022"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeOperatingLeaseDescriptionAbstract_3021" xlink:to="Locator_us-gaap_OperatingLeaseLiability_3022" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAndLiabilitiesLesseeAbstract" xlink:label="Locator_us-gaap_AssetsAndLiabilitiesLesseeAbstract_3013"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseDescriptionAbstract" xlink:label="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3014"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_AssetsAndLiabilitiesLesseeAbstract_3013" xlink:to="Locator_us-gaap_LesseeFinanceLeaseDescriptionAbstract_3014" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_3003"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="Locator_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_3004"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_3003" xlink:to="Locator_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_3004" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_3005"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="Locator_us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1_3006"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_3005" xlink:to="Locator_us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1_3006" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_3007"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent" xlink:label="Locator_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_3008"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_3007" xlink:to="Locator_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_3008" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_3009"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent" xlink:label="Locator_us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent_3010"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_3009" xlink:to="Locator_us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent_3010" order="5.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/LeasesNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_3097"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_3098"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeAxis_3097" xlink:to="Locator_srt_RangeMember_3098" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_3099"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember" xlink:label="Locator_srt_MinimumMember_3100"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_3099" xlink:to="Locator_srt_MinimumMember_3100" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_3101"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember" xlink:label="Locator_srt_MaximumMember_3102"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_3101" xlink:to="Locator_srt_MaximumMember_3102" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="Locator_us-gaap_LeasesAbstract_3069"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionTable_3070"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LeasesAbstract_3069" xlink:to="Locator_us-gaap_LesseeLeaseDescriptionTable_3070" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionTable_3093"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3094"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionTable_3093" xlink:to="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3094" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3053"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseDescription" xlink:label="Locator_us-gaap_LesseeOperatingLeaseDescription_3054"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3053" xlink:to="Locator_us-gaap_LesseeOperatingLeaseDescription_3054" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3055"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_OperatingAndFinanceLeaseRemainingLeaseTerm" xlink:label="Locator_hsic_OperatingAndFinanceLeaseRemainingLeaseTerm_3056"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3055" xlink:to="Locator_hsic_OperatingAndFinanceLeaseRemainingLeaseTerm_3056" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3057"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseOptionToExtend" xlink:label="Locator_us-gaap_LesseeOperatingLeaseOptionToExtend_3058"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3057" xlink:to="Locator_us-gaap_LesseeOperatingLeaseOptionToExtend_3058" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3059"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeFinanceLeaseOptionToExtend" xlink:label="Locator_us-gaap_LesseeFinanceLeaseOptionToExtend_3060"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3059" xlink:to="Locator_us-gaap_LesseeFinanceLeaseOptionToExtend_3060" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3061"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLeaseNotYetCommencedDescription" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLeaseNotYetCommencedDescription_3062"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3061" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLeaseNotYetCommencedDescription_3062" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3063"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_OperatingLeaseAssetsLeaseNotYetCommenced" xlink:label="Locator_hsic_OperatingLeaseAssetsLeaseNotYetCommenced_3064"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3063" xlink:to="Locator_hsic_OperatingLeaseAssetsLeaseNotYetCommenced_3064" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3065"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLeaseNotYetCommencedTermOfContract1" xlink:label="Locator_us-gaap_LesseeOperatingLeaseLeaseNotYetCommencedTermOfContract1_3066"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionLineItems_3065" xlink:to="Locator_us-gaap_LesseeOperatingLeaseLeaseNotYetCommencedTermOfContract1_3066" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable" xlink:label="Locator_us-gaap_LesseeLeaseDescriptionTable_3095"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_3096"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_LesseeLeaseDescriptionTable_3095" xlink:to="Locator_srt_RangeAxis_3096" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/CoverPage">
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3103"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="Locator_dei_EntityCentralIndexKey_3104"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3103" xlink:to="Locator_dei_EntityCentralIndexKey_3104" order="1.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3105"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag" xlink:label="Locator_dei_AmendmentFlag_3106"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3105" xlink:to="Locator_dei_AmendmentFlag_3106" order="2.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3107"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="Locator_dei_DocumentFiscalYearFocus_3108"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3107" xlink:to="Locator_dei_DocumentFiscalYearFocus_3108" order="3.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3109"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="Locator_dei_DocumentFiscalPeriodFocus_3110"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3109" xlink:to="Locator_dei_DocumentFiscalPeriodFocus_3110" order="4.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3111"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="Locator_dei_CurrentFiscalYearEndDate_3112"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3111" xlink:to="Locator_dei_CurrentFiscalYearEndDate_3112" order="5.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3113"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType" xlink:label="Locator_dei_DocumentType_3114"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3113" xlink:to="Locator_dei_DocumentType_3114" order="6.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3115"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentQuarterlyReport" xlink:label="Locator_dei_DocumentQuarterlyReport_3116"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3115" xlink:to="Locator_dei_DocumentQuarterlyReport_3116" order="7.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3117"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="Locator_dei_DocumentPeriodEndDate_3118"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3117" xlink:to="Locator_dei_DocumentPeriodEndDate_3118" order="8.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3119"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentTransitionReport" xlink:label="Locator_dei_DocumentTransitionReport_3120"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3119" xlink:to="Locator_dei_DocumentTransitionReport_3120" order="9.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3121"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName" xlink:label="Locator_dei_EntityRegistrantName_3122"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3121" xlink:to="Locator_dei_EntityRegistrantName_3122" order="10.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3123"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber" xlink:label="Locator_dei_EntityFileNumber_3124"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3123" xlink:to="Locator_dei_EntityFileNumber_3124" order="11.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3125"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="Locator_dei_EntityIncorporationStateCountryCode_3126"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3125" xlink:to="Locator_dei_EntityIncorporationStateCountryCode_3126" order="12.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3127"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:label="Locator_dei_EntityTaxIdentificationNumber_3128"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3127" xlink:to="Locator_dei_EntityTaxIdentificationNumber_3128" order="13.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3129"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1" xlink:label="Locator_dei_EntityAddressAddressLine1_3130"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3129" xlink:to="Locator_dei_EntityAddressAddressLine1_3130" order="14.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3131"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown" xlink:label="Locator_dei_EntityAddressCityOrTown_3132"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3131" xlink:to="Locator_dei_EntityAddressCityOrTown_3132" order="15.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3133"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:label="Locator_dei_EntityAddressStateOrProvince_3134"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3133" xlink:to="Locator_dei_EntityAddressStateOrProvince_3134" order="16.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3135"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:label="Locator_dei_EntityAddressPostalZipCode_3136"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3135" xlink:to="Locator_dei_EntityAddressPostalZipCode_3136" order="17.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3137"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode" xlink:label="Locator_dei_CityAreaCode_3138"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3137" xlink:to="Locator_dei_CityAreaCode_3138" order="18.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3139"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber" xlink:label="Locator_dei_LocalPhoneNumber_3140"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3139" xlink:to="Locator_dei_LocalPhoneNumber_3140" order="19.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3141"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_Security12bTitle" xlink:label="Locator_dei_Security12bTitle_3142"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3141" xlink:to="Locator_dei_Security12bTitle_3142" order="20.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3143"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_TradingSymbol" xlink:label="Locator_dei_TradingSymbol_3144"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3143" xlink:to="Locator_dei_TradingSymbol_3144" order="21.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3145"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SecurityExchangeName" xlink:label="Locator_dei_SecurityExchangeName_3146"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3145" xlink:to="Locator_dei_SecurityExchangeName_3146" order="22.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3147"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCurrentReportingStatus" xlink:label="Locator_dei_EntityCurrentReportingStatus_3148"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3147" xlink:to="Locator_dei_EntityCurrentReportingStatus_3148" order="23.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3149"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityInteractiveDataCurrent" xlink:label="Locator_dei_EntityInteractiveDataCurrent_3150"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3149" xlink:to="Locator_dei_EntityInteractiveDataCurrent_3150" order="24.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3151"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFilerCategory" xlink:label="Locator_dei_EntityFilerCategory_3152"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3151" xlink:to="Locator_dei_EntityFilerCategory_3152" order="25.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3153"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="Locator_dei_EntityEmergingGrowthCompany_3154"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3153" xlink:to="Locator_dei_EntityEmergingGrowthCompany_3154" order="26.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3155"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntitySmallBusiness" xlink:label="Locator_dei_EntitySmallBusiness_3156"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3155" xlink:to="Locator_dei_EntitySmallBusiness_3156" order="27.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3157"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityShellCompany" xlink:label="Locator_dei_EntityShellCompany_3158"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3157" xlink:to="Locator_dei_EntityShellCompany_3158" order="28.0"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="Locator_dei_CoverAbstract_3159"/>
<loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="Locator_dei_EntityCommonStockSharesOutstanding_3160"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_dei_CoverAbstract_3159" xlink:to="Locator_dei_EntityCommonStockSharesOutstanding_3160" order="29.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RelatedPartyTransactions">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="Locator_us-gaap_RelatedPartyTransactionsAbstract_3161"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsDisclosureTextBlock" xlink:label="Locator_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_3162"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionsAbstract_3161" xlink:to="Locator_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_3162" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/RelatedPartyTransactionsNarrativeDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_3273"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_3274"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeAxis_3273" xlink:to="Locator_srt_RangeMember_3274" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember" xlink:label="Locator_srt_RangeMember_3275"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember" xlink:label="Locator_srt_MaximumMember_3276"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_RangeMember_3275" xlink:to="Locator_srt_MaximumMember_3276" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_3283"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_AnimalHealthMember" xlink:label="Locator_hsic_AnimalHealthMember_3284"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_3283" xlink:to="Locator_hsic_AnimalHealthMember_3284" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="Locator_us-gaap_DisposalGroupClassificationAxis_3279"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="Locator_us-gaap_DisposalGroupClassificationDomain_3280"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupClassificationAxis_3279" xlink:to="Locator_us-gaap_DisposalGroupClassificationDomain_3280" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="Locator_us-gaap_DisposalGroupClassificationDomain_3281"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_3282"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisposalGroupClassificationDomain_3281" xlink:to="Locator_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_3282" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis" xlink:label="Locator_srt_StatementScenarioAxis_3269"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain" xlink:label="Locator_srt_ScenarioUnspecifiedDomain_3270"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_StatementScenarioAxis_3269" xlink:to="Locator_srt_ScenarioUnspecifiedDomain_3270" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain" xlink:label="Locator_srt_ScenarioUnspecifiedDomain_3271"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScenarioPlanMember" xlink:label="Locator_us-gaap_ScenarioPlanMember_3272"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_srt_ScenarioUnspecifiedDomain_3271" xlink:to="Locator_us-gaap_ScenarioPlanMember_3272" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="Locator_us-gaap_RelatedPartyTransactionsAbstract_3163"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3164"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionsAbstract_3163" xlink:to="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3164" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3249"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3250"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3249" xlink:to="Locator_us-gaap_RelatedPartyTransactionLineItems_3250" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3165"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionDescriptionOfTransaction" xlink:label="Locator_us-gaap_RelatedPartyTransactionDescriptionOfTransaction_3166"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3165" xlink:to="Locator_us-gaap_RelatedPartyTransactionDescriptionOfTransaction_3166" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3167"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_PeriodCoveredByAgreement" xlink:label="Locator_hsic_PeriodCoveredByAgreement_3168"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3167" xlink:to="Locator_hsic_PeriodCoveredByAgreement_3168" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3169"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionAmountsOfTransaction" xlink:label="Locator_us-gaap_RelatedPartyTransactionAmountsOfTransaction_3170"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3169" xlink:to="Locator_us-gaap_RelatedPartyTransactionAmountsOfTransaction_3170" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3171"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty" xlink:label="Locator_us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty_3172"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3171" xlink:to="Locator_us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty_3172" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3173"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionPurchasesFromRelatedParty" xlink:label="Locator_us-gaap_RelatedPartyTransactionPurchasesFromRelatedParty_3174"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3173" xlink:to="Locator_us-gaap_RelatedPartyTransactionPurchasesFromRelatedParty_3174" order="5.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3175"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromRelatedParties" xlink:label="Locator_us-gaap_RevenueFromRelatedParties_3176"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3175" xlink:to="Locator_us-gaap_RevenueFromRelatedParties_3176" order="6.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3177"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DueFromRelatedParties" xlink:label="Locator_us-gaap_DueFromRelatedParties_3178"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3177" xlink:to="Locator_us-gaap_DueFromRelatedParties_3178" order="7.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3179"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DueToRelatedPartiesCurrentAndNoncurrent" xlink:label="Locator_us-gaap_DueToRelatedPartiesCurrentAndNoncurrent_3180"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3179" xlink:to="Locator_us-gaap_DueToRelatedPartiesCurrentAndNoncurrent_3180" order="8.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3181"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionDueFromToRelatedParty" xlink:label="Locator_us-gaap_RelatedPartyTransactionDueFromToRelatedParty_3182"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3181" xlink:to="Locator_us-gaap_RelatedPartyTransactionDueFromToRelatedParty_3182" order="9.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3183"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfInterestInCorporateUnit" xlink:label="Locator_us-gaap_ProceedsFromSaleOfInterestInCorporateUnit_3184"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3183" xlink:to="Locator_us-gaap_ProceedsFromSaleOfInterestInCorporateUnit_3184" order="10.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="Locator_us-gaap_RelatedPartyTransactionLineItems_3185"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromContributionsFromAffiliates" xlink:label="Locator_us-gaap_ProceedsFromContributionsFromAffiliates_3186"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionLineItems_3185" xlink:to="Locator_us-gaap_ProceedsFromContributionsFromAffiliates_3186" order="11.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3251"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="Locator_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_3252"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3251" xlink:to="Locator_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_3252" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="Locator_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_3261"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="Locator_us-gaap_RelatedPartyDomain_3262"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_3261" xlink:to="Locator_us-gaap_RelatedPartyDomain_3262" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="Locator_us-gaap_RelatedPartyDomain_3263"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_CovetrusIncMember" xlink:label="Locator_hsic_CovetrusIncMember_3264"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyDomain_3263" xlink:to="Locator_hsic_CovetrusIncMember_3264" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="Locator_us-gaap_RelatedPartyDomain_3265"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_InternetBrandsIncMember" xlink:label="Locator_hsic_InternetBrandsIncMember_3266"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyDomain_3265" xlink:to="Locator_hsic_InternetBrandsIncMember_3266" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="Locator_us-gaap_RelatedPartyDomain_3267"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityMethodInvesteeMember" xlink:label="Locator_us-gaap_EquityMethodInvesteeMember_3268"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyDomain_3267" xlink:to="Locator_us-gaap_EquityMethodInvesteeMember_3268" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3253"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis" xlink:label="Locator_srt_StatementScenarioAxis_3254"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3253" xlink:to="Locator_srt_StatementScenarioAxis_3254" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3255"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis" xlink:label="Locator_srt_RangeAxis_3256"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3255" xlink:to="Locator_srt_RangeAxis_3256" order="3.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3257"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="Locator_us-gaap_RelatedPartyTransactionAxis_3258"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3257" xlink:to="Locator_us-gaap_RelatedPartyTransactionAxis_3258" order="4.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="Locator_us-gaap_RelatedPartyTransactionAxis_3277"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="Locator_us-gaap_RelatedPartyTransactionDomain_3278"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_RelatedPartyTransactionAxis_3277" xlink:to="Locator_us-gaap_RelatedPartyTransactionDomain_3278" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3259"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="Locator_us-gaap_DisposalGroupClassificationAxis_3260"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_3259" xlink:to="Locator_us-gaap_DisposalGroupClassificationAxis_3260" order="5.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/StockBasedCompensationBlackScholesValuationModelDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3285"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3286"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3285" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3286" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3287"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_3288"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3287" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_3288" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3289"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_3290"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3289" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_3290" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3291"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_3292"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3291" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_3292" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3293"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_3294"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_3293" xlink:to="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_3294" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/StockBasedCompensationSummaryOfStockOptionActivityDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3295"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3296"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3295" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3296" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3305"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_3306"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3305" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_3306" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3307"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_3308"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3307" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_3308" order="3.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3303"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3304"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3303" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3304" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3309"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3310"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_3309" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3310" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3297"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3298"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3297" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3298" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3313"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_3314"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3313" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_3314" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3315"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_3316"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3315" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_3316" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3311"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3312"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3311" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3312" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3317"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3318"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_3317" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3318" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3299"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_3300"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3299" xlink:to="Locator_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_3300" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3301"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_3302"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_3301" xlink:to="Locator_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_3302" order="4.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/BusinessAcquisitionsTables">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationsAbstract_3319"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock" xlink:label="Locator_us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_3320"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationsAbstract_3319" xlink:to="Locator_us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_3320" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/BusinessAcquisitionsAcquisitionConsiderationDetails">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationsAbstract_3321"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3322"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationsAbstract_3321" xlink:to="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3322" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3407"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="Locator_us-gaap_BusinessAcquisitionLineItems_3408"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3407" xlink:to="Locator_us-gaap_BusinessAcquisitionLineItems_3408" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="Locator_us-gaap_BusinessAcquisitionLineItems_3323"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredAbstract" xlink:label="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3324"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionLineItems_3323" xlink:to="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3324" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredAbstract" xlink:label="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3329"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross" xlink:label="Locator_us-gaap_PaymentsToAcquireBusinessesGross_3330"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3329" xlink:to="Locator_us-gaap_PaymentsToAcquireBusinessesGross_3330" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredAbstract" xlink:label="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3331"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncontrollingInterestIncreaseFromBusinessCombination" xlink:label="Locator_us-gaap_NoncontrollingInterestIncreaseFromBusinessCombination_3332"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3331" xlink:to="Locator_us-gaap_NoncontrollingInterestIncreaseFromBusinessCombination_3332" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredAbstract" xlink:label="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3333"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1" xlink:label="Locator_us-gaap_BusinessCombinationConsiderationTransferred1_3334"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationConsiderationTransferredAbstract_3333" xlink:to="Locator_us-gaap_BusinessCombinationConsiderationTransferred1_3334" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="Locator_us-gaap_BusinessAcquisitionLineItems_3325"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3326"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionLineItems_3325" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3326" order="2.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3335"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssets" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssets_3336"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3335" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssets_3336" order="1.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3337"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_3338"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3337" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_3338" order="2.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3339"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_3340"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3339" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_3340" order="3.0" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3341"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities_3342"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3341" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities_3342" order="4.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3343"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_3344"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3343" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_3344" order="5.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3345"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther_3346"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3345" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther_3346" order="6.0" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3347"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_3348"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3347" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_3348" order="7.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3349"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill" xlink:label="Locator_us-gaap_Goodwill_3350"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3349" xlink:to="Locator_us-gaap_Goodwill_3350" order="8.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3351"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet" xlink:label="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_3352"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAbstract_3351" xlink:to="Locator_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_3352" order="9.0" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3409"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="Locator_us-gaap_BusinessAcquisitionAxis_3410"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3409" xlink:to="Locator_us-gaap_BusinessAcquisitionAxis_3410" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="Locator_us-gaap_BusinessAcquisitionAxis_3411"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_3412"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionAxis_3411" xlink:to="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_3412" order="1.0"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_3413"/>
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SeriesOfIndividuallyImmaterialBusinessAcquisitionsMember" xlink:label="Locator_us-gaap_SeriesOfIndividuallyImmaterialBusinessAcquisitionsMember_3414"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_BusinessAcquisitionAcquireeDomain_3413" xlink:to="Locator_us-gaap_SeriesOfIndividuallyImmaterialBusinessAcquisitionsMember_3414" order="1.0"/>
</presentationLink>
<presentationLink xlink:type="extended" xlink:role="http://henryschein.com/role/DebtPrivatePlacementFacilitiesNarrative2Details">
<loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="Locator_us-gaap_DebtDisclosureAbstract_3415"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_NumberOfLendersAbstract" xlink:label="Locator_hsic_NumberOfLendersAbstract_3416"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_us-gaap_DebtDisclosureAbstract_3415" xlink:to="Locator_hsic_NumberOfLendersAbstract_3416" order="1.0"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_NumberOfLendersAbstract" xlink:label="Locator_hsic_NumberOfLendersAbstract_3417"/>
<loc xlink:type="locator" xlink:href="hsic-20210327.xsd#hsic_NumberOfLenders" xlink:label="Locator_hsic_NumberOfLenders_3418"/>
<presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="Locator_hsic_NumberOfLendersAbstract_3417" xlink:to="Locator_hsic_NumberOfLenders_3418" order="1.0"/>
</presentationLink>
</linkbase>


2 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 2/21/23  Henry Schein Inc.                 10-K       12/31/22  133:16M
 2/15/22  Henry Schein Inc.                 10-K       12/25/21  127:22M


2 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/08/21  Henry Schein Inc.                 8-K:1,2,5,7 3/03/21   15:469K                                   Donnelley … Solutions/FA
 4/23/18  Henry Schein Inc.                 8-K:1,9     4/20/18    5:1.1M                                   Donnelley … Solutions/FA
Top
Filing Submission 0001000228-21-000036   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)

Copyright © 2024 Fran Finnegan & Company LLC – All Rights Reserved.
AboutPrivacyRedactionsHelp — Tue., Apr. 30, 4:25:03.2am ET