SEC Info℠  
    Home      Search      My Interests      Help      Sign In      Please Sign In

PPG Industries Inc. – ‘10-K’ for 12/31/20 – ‘EX-101.DEF’

On:  Thursday, 2/18/21, at 1:00pm ET   ·   For:  12/31/20   ·   Accession #:  79879-21-8   ·   File #:  1-01687

Previous ‘10-K’:  ‘10-K’ on 2/20/20 for 12/31/19   ·   Next:  ‘10-K’ on 2/17/22 for 12/31/21   ·   Latest:  ‘10-K’ on 2/15/24 for 12/31/23   ·   33 References:   

Find Words in Filings emoji
 		  in    Show  and   ↓Hints

  As Of               Filer                 Filing    For·On·As Docs:Size

 2/18/21  PPG Industries Inc.               10-K       12/31/20  133:19M

Annual Report   —   Form 10-K
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   1.94M 
 2: EX-4.10     Instrument Defining the Rights of Security Holders  HTML     78K 
 3: EX-13.1     Annual or Quarterly Report to Security Holders      HTML     49K 
 4: EX-13.2     Annual or Quarterly Report to Security Holders      HTML     45K 
 5: EX-21       Subsidiaries List                                   HTML     87K 
 6: EX-23       Consent of Expert or Counsel                        HTML     35K 
 7: EX-24       Power of Attorney                                   HTML     49K 
 8: EX-31.1     Certification -- §302 - SOA'02                      HTML     39K 
 9: EX-31.2     Certification -- §302 - SOA'02                      HTML     39K 
10: EX-32.1     Certification -- §906 - SOA'02                      HTML     36K 
11: EX-32.2     Certification -- §906 - SOA'02                      HTML     36K 
18: R1          Cover                                               HTML    107K 
19: R2          Consolidated Statement of Income                    HTML    151K 
20: R3          Consolidated Statement of Comprehensive Income      HTML     71K 
21: R4          Consolidated Balance Sheet                          HTML    148K 
22: R5          Consolidated Statement of Shareholders' Equity      HTML     90K 
23: R6          Consolidated Statement of Cash Flows                HTML    186K 
24: R7          Summary of Significant Accounting Policies          HTML     79K 
25: R8          Credit Losses                                       HTML     44K 
26: R9          Acquisitions and Dispositions                       HTML     64K 
27: R10         Working Capital Detail                              HTML     61K 
28: R11         Property, Plant and Equipment                       HTML     51K 
29: R12         Investments                                         HTML     44K 
30: R13         Goodwill and Other Identifiable Intangible Assets   HTML     79K 
31: R14         Business Restructuring                              HTML     50K 
32: R15         Leases                                              HTML     89K 
33: R16         Borrowings and Lines of Credit                      HTML     95K 
34: R17         Financial Instruments, Hedging Activities and Fair  HTML    129K 
                Value Measurements                                               
35: R18         Earnings Per Common Share                           HTML     64K 
36: R19         Income Taxes                                        HTML    132K 
37: R20         Employee Benefit Plans                              HTML    339K 
38: R21         Commitments and Contingent Liabilities              HTML     82K 
39: R22         Shareholders' Equity                                HTML     54K 
40: R23         Accumulated Other Comprehensive Loss                HTML     78K 
41: R24         Other Income                                        HTML     47K 
42: R25         Stock-Based Compensation                            HTML     99K 
43: R26         Quarterly Financial Information (Unaudited)         HTML     95K 
44: R27         Revenue Recognition                                 HTML     70K 
45: R28         Reportable Business Segment Information             HTML    148K 
46: R29         Summary of Significant Accounting Policies          HTML    133K 
                (Policies)                                                       
47: R30         Summary of Significant Accounting Policies          HTML     44K 
                (Tables)                                                         
48: R31         Credit Losses (Tables)                              HTML     41K 
49: R32         Acquisitions and Dispositions (Tables)              HTML     57K 
50: R33         Working Capital Detail (Tables)                     HTML     62K 
51: R34         Property, Plant and Equipment (Tables)              HTML     51K 
52: R35         Investments (Tables)                                HTML     43K 
53: R36         Goodwill and Other Identifiable Intangible Assets   HTML     81K 
                (Tables)                                                         
54: R37         Business Restructuring (Tables)                     HTML     46K 
55: R38         Leases (Tables)                                     HTML    163K 
56: R39         Borrowings and Lines of Credit (Tables)             HTML     90K 
57: R40         Financial Instruments, Hedging Activities and Fair  HTML    157K 
                Value Measurements (Tables)                                      
58: R41         Earnings Per Common Share (Tables)                  HTML     63K 
59: R42         Income Taxes (Tables)                               HTML    133K 
60: R43         Employee Benefit Plans (Tables)                     HTML    338K 
61: R44         Commitments and Contingent Liabilities (Tables)     HTML     57K 
62: R45         Shareholders' Equity (Tables)                       HTML     52K 
63: R46         Accumulated Other Comprehensive Loss (Tables)       HTML     77K 
64: R47         Other Income (Tables)                               HTML     46K 
65: R48         Stock-Based Compensation (Tables)                   HTML     97K 
66: R49         Quarterly Financial Information (Tables)            HTML     95K 
67: R50         Revenue Recognition (Tables)                        HTML     65K 
68: R51         Reportable Business Segment Information (Tables)    HTML    142K 
69: R52         Summary of Significant Accounting Policies          HTML     59K 
                (Additional Information) (Detail)                                
70: R53         Credit Losses (Details)                             HTML     46K 
71: R54         Acquisitions and Dispositions (Acquistions)         HTML     41K 
                (Detail)                                                         
72: R55         Acquisitions and Dispositions (Divestitures, Major  HTML     71K 
                Classes of Assets and Liabilities) (Details)                     
73: R56         Acquisitions and Dispositions (Divestitures, Glass  HTML     64K 
                Segment) (Details)                                               
74: R57         Working Capital Detail (Detail)                     HTML     72K 
75: R58         Working Capital Detail (Additional Information)     HTML     41K 
                (Detail)                                                         
76: R59         Property, Plant and Equipment (Detail)              HTML     70K 
77: R60         Investments (Detail)                                HTML     56K 
78: R61         Goodwill and Other Identifiable Intangible Assets   HTML     53K 
                (Carrying Amount of Goodwill Attributable to Each                
                Reportable Segment) (Detail)                                     
79: R62         Goodwill and Other Identifiable Intangible Assets   HTML     83K 
                (Identifiable Intangible Assets with Finite Lives)               
                (Detail)                                                         
80: R63         Business Restructuring (Additional Information)     HTML     61K 
                (Detail)                                                         
81: R64         Leases - Schedule of Components of Lease Expense    HTML     57K 
                (Details)                                                        
82: R65         Leases - Additional Information (Details)           HTML     37K 
83: R66         Leases - Schedule of Classification on the          HTML     53K 
                Condensed Consolidated Balance Sheet (Details)                   
84: R67         Leases - Schedule of Cash Paid for Lease            HTML     47K 
                Liabilities and Right-of-Use Assets Obtained in                  
                Exchange for Lease Obligations (Details)                         
85: R68         Leases - Schedule of Weighted-Average Remaining     HTML     45K 
                Lease Term and Weighted-Average Discount Rate                    
                (Details)                                                        
86: R69         Leases - Schedule of Maturities of Lease            HTML     75K 
                Liabilities (Details)                                            
87: R70         Borrowings and Lines of Credit (Long-term Debt      HTML    211K 
                Obligations) (Details)                                           
88: R71         Borrowings and Lines of Credit (Long-term Debt      HTML     51K 
                Maturities) (Details)                                            
89: R72         Borrowings and Lines of Credit (Short-term Debt     HTML     44K 
                Outstanding) (Detail)                                            
90: R73         Borrowings and Lines of Credit (Additional          HTML     81K 
                Information) (Details)                                           
91: R74         Financial Instruments, Hedging Activities and Fair  HTML     87K 
                Value Measurements (Additional Information)                      
                (Detail)                                                         
92: R75         Financial Instruments, Hedging Activities and Fair  HTML     64K 
                Value Measurements (Fair Value, Cash Flow and Net                
                Investment Hedges) (Detail)                                      
93: R76         Financial Instruments, Hedging Activities and Fair  HTML     64K 
                Value Measurements (Assets and Liabilities                       
                Reported at Fair Value on a Recurring Basis)                     
                (Detail)                                                         
94: R77         Financial Instruments, Hedging Activities and Fair  HTML     48K 
                Value Measurements (Fair Value Additional                        
                Information) (Detail)                                            
95: R78         Earnings Per Common Share (Additional Detail)       HTML    110K 
                (Detail)                                                         
96: R79         Income Taxes (Additional Information) (Detail)      HTML     84K 
97: R80         Income Taxes (Components of Income Tax Expense)     HTML     63K 
                (Detail)                                                         
98: R81         Income Taxes (Reconciliation of Statutory U.S.      HTML     61K 
                Corporate Federal Income Tax Rate to Effective                   
                Income Tax Rate) (Detail)                                        
99: R82         Income Taxes (Net Deferred Income Tax Assets and    HTML     91K 
                Liabilities) (Detail)                                            
100: R83         Income Taxes (Unrecognized Tax Benefits) (Detail)   HTML     56K  
101: R84         Employee Benefit Plans (Additional Information)     HTML    137K  
                (Detail)                                                         
102: R85         Employee Benefit Plans (Changes in Projected        HTML    146K  
                Benefit Obligations, Plan Assets and Funded                      
                Status) (Detail)                                                 
103: R86         Employee Benefit Plans (Accumulated Other           HTML     48K  
                Comprehensive Loss Pretax Amounts Not Yet                        
                Reflected in Net Periodic Benefit Cost) (Details)                
104: R87         Employee Benefit Plans (Change in Accumulated       HTML     63K  
                Other Comprehensive Loss (Pretax) Relating to                    
                Defined Benefit Pension and Other Postretirement                 
                Benefits) (Detail)                                               
105: R88         Employee Benefit Plans (Net Periodic Benefit        HTML     63K  
                Costs) (Detail)                                                  
106: R89         Employee Benefit Plans (Weighted Average            HTML     49K  
                Assumptions Used to Determine Benefit Obligation                 
                for Defined Benefit Pension and Other                            
                Postretirement Plans) (Detail)                                   
107: R90         Employee Benefit Plans (Weighted Average            HTML     48K  
                Assumptions Used to Determine Net Periodic Benefit               
                Cost for Defined Benefit Pension and Other                       
                Postretirement Plans) (Detail)                                   
108: R91         Employee Benefit Plans (Weighted Average Target     HTML     52K  
                Pension Plan Asset Allocations) (Detail)                         
109: R92         Employee Benefit Plans (Fair Values of the          HTML    119K  
                Company's Pension Plan Assets by Asset Category)                 
                (Detail)                                                         
110: R93         Employee Benefit Plans (Change in Fair Value of     HTML     64K  
                Company's Level 3 Pension Assets) (Detail)                       
111: R94         Employee Benefit Plans (Other Plans) (Details)      HTML     52K  
112: R95         Commitments and Contingent Liabilities              HTML     39K  
                (Shareholder Class Action) (Details)                             
113: R96         Commitments and Contingent Liabilities (Litigation  HTML     45K  
                Settlements - Asbestos Matters and Other                         
                Disclosure) (Detail)                                             
114: R97         Commitments and Contingent Liabilities (Additional  HTML     89K  
                Information - Environmental Matters) (Detail)                    
115: R98         Shareholders' Equity (Summary of Shares             HTML     60K  
                Outstanding) (Detail)                                            
116: R99         Accumulated Other Comprehensive Loss (Detail)       HTML     84K  
117: R100        Accumulated Other Comprehensive Loss (Additional    HTML     47K  
                Information) (Detail)                                            
118: R101        Other Income (Detail)                               HTML     49K  
119: R102        Stock-Based Compensation (Additional Information)   HTML     90K  
                (Detail)                                                         
120: R103        Stock-Based Compensation (Weighted Average          HTML     48K  
                Assumptions Used in Calculating Fair Value of                    
                Stock Option) (Details)                                          
121: R104        Stock-Based Compensation (Stock Options             HTML     87K  
                Outstanding, Exercisable and Activity) (Detail)                  
122: R105        Stock-Based Compensation (Stock Option Activity)    HTML     44K  
                (Details)                                                        
123: R106        Stock-Based Compensation (RSU Activity) (Details)   HTML     68K  
124: R107        Quarterly Financial Information Quarterly           HTML     96K  
                Financial Information (Unaudited) (Details)                      
125: R108        Revenue Recognition Schedule Of Revenue (Details)   HTML     83K  
126: R109        Reportable Business Segment Information             HTML     39K  
                (Reportable Segment Information) (Detail)                        
127: R110        Reportable Business Segment Information             HTML    117K  
                (Reportable Segment Tables) (Detail)                             
128: R111        Reportable Business Segment Information             HTML     66K  
                (Geographic Information) (Detail)                                
129: R112        Schedule II - Valuation and Qualifying Accounts     HTML     58K  
                (Detail)                                                         
131: XML         IDEA XML File -- Filing Summary                      XML    254K  
17: XML         XBRL Instance -- ppg-20201231_htm                    XML   5.51M 
130: EXCEL       IDEA Workbook of Financial Reports                  XLSX    193K  
13: EX-101.CAL  XBRL Calculations -- ppg-20201231_cal                XML    435K 
14: EX-101.DEF  XBRL Definitions -- ppg-20201231_def                 XML   1.21M 
15: EX-101.LAB  XBRL Labels -- ppg-20201231_lab                      XML   3.05M 
16: EX-101.PRE  XBRL Presentations -- ppg-20201231_pre               XML   1.88M 
12: EX-101.SCH  XBRL Schema -- ppg-20201231                          XSD    291K 
132: JSON        XBRL Instance as JSON Data -- MetaLinks              707±  1.05M  
133: ZIP         XBRL Zipped Folder -- 0000079879-21-000008-xbrl      Zip    649K

‘EX-101.DEF’   —   XBRL Definitions — ppg-20201231_def

This Exhibit is an XBRL XML File.

                                                                                                                                                                                
<?xml version="1.0" encoding="windows-1252"?>
<!-- XBRL Document Created with Wdesk from Workiva -->
<!-- Copyright 2021 Workiva -->
<!-- r:1dba323e-e120-4bbc-a63a-045b742cd46f,g:d3a8ab36-ccdf-4226-b98b-8f9a0578d636 -->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member"/>
<link:roleRef roleURI="http://www.ppg.com/role/Cover" xlink:type="simple" xlink:href="ppg-20201231.xsd#Cover"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/Cover" xlink:type="extended" id="i53b12fe217fb493e97d93211cb27eeba_Cover">
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityInformationLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_9b660428-89a0-430f-addb-3b3da7d495c1" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_DocumentType_9b660428-89a0-430f-addb-3b3da7d495c1" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentAnnualReport_cae5c88e-254e-465c-84fe-5c6381928dcd" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentAnnualReport"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_DocumentAnnualReport_cae5c88e-254e-465c-84fe-5c6381928dcd" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_c6b17bfc-58cc-459e-a65a-4d209b624c6c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentTransitionReport"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_DocumentTransitionReport_c6b17bfc-58cc-459e-a65a-4d209b624c6c" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_b05ce8a1-1df5-45cd-8b67-1f4fa98c391f" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_DocumentPeriodEndDate_b05ce8a1-1df5-45cd-8b67-1f4fa98c391f" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_157f37e0-ed7e-4b55-9dc7-c38e8d652a14" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityFileNumber_157f37e0-ed7e-4b55-9dc7-c38e8d652a14" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_5fb9ed49-fd2a-432e-9c61-65e1bc508454" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityRegistrantName_5fb9ed49-fd2a-432e-9c61-65e1bc508454" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_11b564ad-62c6-4e13-bbb7-45f56f65ce53" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityIncorporationStateCountryCode_11b564ad-62c6-4e13-bbb7-45f56f65ce53" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_d88d164d-4aa0-46a7-bf19-0dd6be9382e5" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityTaxIdentificationNumber_d88d164d-4aa0-46a7-bf19-0dd6be9382e5" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_1e039181-1447-4fa4-abc1-5cb5482d435c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityAddressAddressLine1_1e039181-1447-4fa4-abc1-5cb5482d435c" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_344bbf20-7f34-4d72-863a-477040f0bbd8" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityAddressCityOrTown_344bbf20-7f34-4d72-863a-477040f0bbd8" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_a7971e97-4622-4dc9-b8b9-74835b2ad530" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressStateOrProvince"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityAddressStateOrProvince_a7971e97-4622-4dc9-b8b9-74835b2ad530" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_916aad59-c91b-4970-9f36-519ece5f01c5" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityAddressPostalZipCode_916aad59-c91b-4970-9f36-519ece5f01c5" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_9c86ed0a-f1e2-4fd9-9a49-296178eadd0c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_CityAreaCode_9c86ed0a-f1e2-4fd9-9a49-296178eadd0c" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_3b6e63a2-02d6-41ee-8957-acf1e65cd415" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_LocalPhoneNumber_3b6e63a2-02d6-41ee-8957-acf1e65cd415" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_8133007a-2d1c-4e01-880e-1e49e6605799" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_Security12bTitle"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_Security12bTitle_8133007a-2d1c-4e01-880e-1e49e6605799" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_343d37ab-234e-491c-a0ff-0835934c81a0" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_TradingSymbol"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_TradingSymbol_343d37ab-234e-491c-a0ff-0835934c81a0" xlink:type="arc" order="15"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_6f0bfa6e-d918-4897-a417-c363d7a5fa9a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SecurityExchangeName"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_SecurityExchangeName_6f0bfa6e-d918-4897-a417-c363d7a5fa9a" xlink:type="arc" order="16"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityWellKnownSeasonedIssuer_44d03184-008e-41a6-b570-f9fcb2168f64" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityWellKnownSeasonedIssuer"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityWellKnownSeasonedIssuer_44d03184-008e-41a6-b570-f9fcb2168f64" xlink:type="arc" order="17"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityVoluntaryFilers_c29eaf9b-4189-40a1-9fc0-801cb6875f30" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityVoluntaryFilers"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityVoluntaryFilers_c29eaf9b-4189-40a1-9fc0-801cb6875f30" xlink:type="arc" order="18"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_96e8ab8e-be02-4536-b24c-baa8ce68d16e" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCurrentReportingStatus"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityCurrentReportingStatus_96e8ab8e-be02-4536-b24c-baa8ce68d16e" xlink:type="arc" order="19"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_6f67fe05-57a6-4094-a405-e273f40aae40" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityInteractiveDataCurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityInteractiveDataCurrent_6f67fe05-57a6-4094-a405-e273f40aae40" xlink:type="arc" order="20"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_9d4be2f1-9589-47b3-929a-60964ec8b4f6" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFilerCategory"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityFilerCategory_9d4be2f1-9589-47b3-929a-60964ec8b4f6" xlink:type="arc" order="21"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_93f6a27f-fb07-4c67-adab-2c7307c60938" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntitySmallBusiness"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntitySmallBusiness_93f6a27f-fb07-4c67-adab-2c7307c60938" xlink:type="arc" order="22"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_633cb6e6-a08e-4c38-8d82-60f695342a20" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityEmergingGrowthCompany_633cb6e6-a08e-4c38-8d82-60f695342a20" xlink:type="arc" order="23"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_4ffd8ea2-853f-4696-8750-ca3978cb6bbc" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityShellCompany"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityShellCompany_4ffd8ea2-853f-4696-8750-ca3978cb6bbc" xlink:type="arc" order="24"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityPublicFloat_b597d215-48b8-4726-9f1a-09ccf5acce7a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityPublicFloat"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityPublicFloat_b597d215-48b8-4726-9f1a-09ccf5acce7a" xlink:type="arc" order="25"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_5ec1337c-8a2a-495b-bc13-31e73b941cdb" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCommonStockSharesOutstanding"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_5ec1337c-8a2a-495b-bc13-31e73b941cdb" xlink:type="arc" order="26"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentsIncorporatedByReferenceTextBlock_68fc16bd-bf93-4df8-992b-99f54acb5e54" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentsIncorporatedByReferenceTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_DocumentsIncorporatedByReferenceTextBlock_68fc16bd-bf93-4df8-992b-99f54acb5e54" xlink:type="arc" order="27"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_73ec26c4-4d24-4e68-8a73-8d9b71971a6b" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_AmendmentFlag_73ec26c4-4d24-4e68-8a73-8d9b71971a6b" xlink:type="arc" order="28"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_cace80b4-6c47-41c5-bfbc-698ba692d37a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalYearFocus"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_DocumentFiscalYearFocus_cace80b4-6c47-41c5-bfbc-698ba692d37a" xlink:type="arc" order="29"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_fae1dcfd-819f-4256-85a4-12321ba04ff7" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalPeriodFocus"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_DocumentFiscalPeriodFocus_fae1dcfd-819f-4256-85a4-12321ba04ff7" xlink:type="arc" order="30"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_44bb04c8-f062-4bba-8156-fca078766b49" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntityCentralIndexKey_44bb04c8-f062-4bba-8156-fca078766b49" xlink:type="arc" order="31"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_6d831eef-6c26-4237-9252-0994eba9822c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CurrentFiscalYearEndDate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_CurrentFiscalYearEndDate_6d831eef-6c26-4237-9252-0994eba9822c" xlink:type="arc" order="32"/>
<link:loc xlink:type="locator" xlink:label="loc_dei_EntitiesTable_c1151bb2-a6a8-44e9-a357-778f9fe163ae" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntitiesTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_dei_EntityInformationLineItems_8692a4e0-7a4d-4f1a-ae7c-f02eb07b8f1a" xlink:to="loc_dei_EntitiesTable_c1151bb2-a6a8-44e9-a357-778f9fe163ae" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_c02ebca7-4c02-4a90-9f9e-5ab1a4c11062" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_dei_EntitiesTable_c1151bb2-a6a8-44e9-a357-778f9fe163ae" xlink:to="loc_us-gaap_StatementClassOfStockAxis_c02ebca7-4c02-4a90-9f9e-5ab1a4c11062" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_c02ebca7-4c02-4a90-9f9e-5ab1a4c11062_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementClassOfStockAxis_c02ebca7-4c02-4a90-9f9e-5ab1a4c11062" xlink:to="loc_us-gaap_ClassOfStockDomain_c02ebca7-4c02-4a90-9f9e-5ab1a4c11062_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_e7d5d9bf-5a7b-4f5c-8a26-bb3ed0f9c8b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementClassOfStockAxis_c02ebca7-4c02-4a90-9f9e-5ab1a4c11062" xlink:to="loc_us-gaap_ClassOfStockDomain_e7d5d9bf-5a7b-4f5c-8a26-bb3ed0f9c8b8" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_809f783e-f717-4357-af5e-a36d46047391" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_e7d5d9bf-5a7b-4f5c-8a26-bb3ed0f9c8b8" xlink:to="loc_us-gaap_CommonStockMember_809f783e-f717-4357-af5e-a36d46047391" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A0.875NotesDue2022Member_65824437-d778-4e1a-8065-1433444e8976" xlink:href="ppg-20201231.xsd#ppg_A0.875NotesDue2022Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_e7d5d9bf-5a7b-4f5c-8a26-bb3ed0f9c8b8" xlink:to="loc_ppg_A0.875NotesDue2022Member_65824437-d778-4e1a-8065-1433444e8976" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A0.875NotesDue2025Member_1a627dbb-2edc-41f7-bc46-1b012d39541f" xlink:href="ppg-20201231.xsd#ppg_A0.875NotesDue2025Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_e7d5d9bf-5a7b-4f5c-8a26-bb3ed0f9c8b8" xlink:to="loc_ppg_A0.875NotesDue2025Member_1a627dbb-2edc-41f7-bc46-1b012d39541f" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A1.400NotesDue2027Member_77e69dc5-db52-408a-a7f0-bd5a5b290d90" xlink:href="ppg-20201231.xsd#ppg_A1.400NotesDue2027Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_e7d5d9bf-5a7b-4f5c-8a26-bb3ed0f9c8b8" xlink:to="loc_ppg_A1.400NotesDue2027Member_77e69dc5-db52-408a-a7f0-bd5a5b290d90" xlink:type="arc" order="3"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/ConsolidatedStatementofIncome" xlink:type="simple" xlink:href="ppg-20201231.xsd#ConsolidatedStatementofIncome"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ConsolidatedStatementofIncome" xlink:type="extended" id="if3f136a2a6df418a92dc88876ccb17d0_ConsolidatedStatementofIncome"/>
<link:roleRef roleURI="http://www.ppg.com/role/ConsolidatedStatementofComprehensiveIncome" xlink:type="simple" xlink:href="ppg-20201231.xsd#ConsolidatedStatementofComprehensiveIncome"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ConsolidatedStatementofComprehensiveIncome" xlink:type="extended" id="i131676a6225c49d493f7ab2551bf155f_ConsolidatedStatementofComprehensiveIncome"/>
<link:roleRef roleURI="http://www.ppg.com/role/ConsolidatedBalanceSheet" xlink:type="simple" xlink:href="ppg-20201231.xsd#ConsolidatedBalanceSheet"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ConsolidatedBalanceSheet" xlink:type="extended" id="i999b4a1b753a4ac6aa39030522795c63_ConsolidatedBalanceSheet"/>
<link:roleRef roleURI="http://www.ppg.com/role/ConsolidatedStatementofShareholdersEquity" xlink:type="simple" xlink:href="ppg-20201231.xsd#ConsolidatedStatementofShareholdersEquity"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ConsolidatedStatementofShareholdersEquity" xlink:type="extended" id="i92369db3ac8d4932afb4dfba328eb044_ConsolidatedStatementofShareholdersEquity">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_a9d3858a-8f6e-4d22-a61a-eea25a3d9a53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_a9d3858a-8f6e-4d22-a61a-eea25a3d9a53" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_77dce429-d07b-415d-9b72-84962a115863" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_77dce429-d07b-415d-9b72-84962a115863" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProfitLoss_9f8e6ef6-3ac3-4fa9-84c8-ad2d4482aa02" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProfitLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_ProfitLoss_9f8e6ef6-3ac3-4fa9-84c8-ad2d4482aa02" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_677fbef7-b99d-4065-9462-c4b4cb65aae6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_677fbef7-b99d-4065-9462-c4b4cb65aae6" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsCommonStockCash_1426d0da-33d1-41e3-a671-dfdb630d269d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DividendsCommonStockCash"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_DividendsCommonStockCash_1426d0da-33d1-41e3-a671-dfdb630d269d" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_b2672a5e-d2ad-4922-a57b-4afa7499ea03" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_b2672a5e-d2ad-4922-a57b-4afa7499ea03" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueTreasuryStockReissued_f202eb21-f1f8-47b5-a2e3-b04dff769de4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueTreasuryStockReissued"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueTreasuryStockReissued_f202eb21-f1f8-47b5-a2e3-b04dff769de4" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition_66a9ee39-7b47-4802-8bd8-d99d85d3864a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition_66a9ee39-7b47-4802-8bd8-d99d85d3864a" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MinorityInterestDecreaseFromDistributionsToNoncontrollingInterestHolders_94768fd0-4d22-40a1-95dc-e688dd9d0cb2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MinorityInterestDecreaseFromDistributionsToNoncontrollingInterestHolders"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_MinorityInterestDecreaseFromDistributionsToNoncontrollingInterestHolders_94768fd0-4d22-40a1-95dc-e688dd9d0cb2" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MinorityInterestDecreaseFromRedemptions_6e15f6be-11c0-47ba-8554-6b311190dc79" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MinorityInterestDecreaseFromRedemptions"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_MinorityInterestDecreaseFromRedemptions_6e15f6be-11c0-47ba-8554-6b311190dc79" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationsOfTemporaryToPermanentEquity_333529bb-26ec-4836-8362-8af30db2dacc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReclassificationsOfTemporaryToPermanentEquity"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_ReclassificationsOfTemporaryToPermanentEquity_333529bb-26ec-4836-8362-8af30db2dacc" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityOther_af2205f7-561f-43b4-b6b4-3125adc96cf7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityOther"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_2160b3ac-c097-4b44-bd05-dbbe23cf0200" xlink:to="loc_us-gaap_StockholdersEquityOther_af2205f7-561f-43b4-b6b4-3125adc96cf7" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_eacf7a70-97b5-4a68-b7f3-435194ef51fc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_3b6396b7-0bcb-408f-9a63-d665e32b883c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_a9d3858a-8f6e-4d22-a61a-eea25a3d9a53" xlink:to="loc_us-gaap_StatementTable_3b6396b7-0bcb-408f-9a63-d665e32b883c" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_884d1a6a-2b49-472d-99ab-056293d057a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_3b6396b7-0bcb-408f-9a63-d665e32b883c" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_884d1a6a-2b49-472d-99ab-056293d057a7" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_884d1a6a-2b49-472d-99ab-056293d057a7_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_884d1a6a-2b49-472d-99ab-056293d057a7" xlink:to="loc_us-gaap_EquityComponentDomain_884d1a6a-2b49-472d-99ab-056293d057a7_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_884d1a6a-2b49-472d-99ab-056293d057a7" xlink:to="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_aab6b5e7-d050-4d15-9678-bedc8fa0cf3a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:to="loc_us-gaap_CommonStockMember_aab6b5e7-d050-4d15-9678-bedc8fa0cf3a" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_6e2249d9-4b8e-4364-bd59-15d20d73f477" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_6e2249d9-4b8e-4364-bd59-15d20d73f477" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_f342849d-5c70-45e3-9db7-9b172cfecf33" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:to="loc_us-gaap_RetainedEarningsMember_f342849d-5c70-45e3-9db7-9b172cfecf33" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockMember_eb88e1d7-3f82-4e84-ba19-70bd5028b404" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:to="loc_us-gaap_TreasuryStockMember_eb88e1d7-3f82-4e84-ba19-70bd5028b404" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_d7e7f344-7ae1-417c-af4b-7a834069d61d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_d7e7f344-7ae1-417c-af4b-7a834069d61d" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ParentMember_0c42d10c-efbd-479b-903d-36a0a6c7c925" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:to="loc_us-gaap_ParentMember_0c42d10c-efbd-479b-903d-36a0a6c7c925" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoncontrollingInterestMember_522341e3-fa2e-42af-be2b-f4ddcda4d336" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NoncontrollingInterestMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_5bf78b99-1665-437f-9fe4-ae395283d3b4" xlink:to="loc_us-gaap_NoncontrollingInterestMember_522341e3-fa2e-42af-be2b-f4ddcda4d336" xlink:type="arc" order="6"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/ConsolidatedStatementofCashFlows" xlink:type="simple" xlink:href="ppg-20201231.xsd#ConsolidatedStatementofCashFlows"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ConsolidatedStatementofCashFlows" xlink:type="extended" id="i46fee12a19474040bc6c39c7a7bf92c7_ConsolidatedStatementofCashFlows"/>
<link:roleRef roleURI="http://www.ppg.com/role/SummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="ppg-20201231.xsd#SummaryofSignificantAccountingPolicies"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/SummaryofSignificantAccountingPolicies" xlink:type="extended" id="i9199f383ac4245f2aedf306dce455325_SummaryofSignificantAccountingPolicies"/>
<link:roleRef roleURI="http://www.ppg.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="ppg-20201231.xsd#SummaryofSignificantAccountingPoliciesPolicies"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended" id="if5a4176bb1ed4a97a879247b9a12493b_SummaryofSignificantAccountingPoliciesPolicies"/>
<link:roleRef roleURI="http://www.ppg.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#SummaryofSignificantAccountingPoliciesTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="extended" id="i801f6f5a562540c899ef4c236800eebf_SummaryofSignificantAccountingPoliciesTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/SummaryofSignificantAccountingPoliciesAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#SummaryofSignificantAccountingPoliciesAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/SummaryofSignificantAccountingPoliciesAdditionalInformationDetail" xlink:type="extended" id="i85b6fef455414095b3768f3ef69a7902_SummaryofSignificantAccountingPoliciesAdditionalInformationDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdvertisingExpense_1a9149ca-ce26-477c-a587-1ed64477e78d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdvertisingExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_AdvertisingExpense_1a9149ca-ce26-477c-a587-1ed64477e78d" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_bf893f03-9999-49ce-a4e7-3d35d7095f0c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_bf893f03-9999-49ce-a4e7-3d35d7095f0c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationNonproduction_77b8884b-387e-46f2-8dbf-c2e8ede87db5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationNonproduction"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_DepreciationNonproduction_77b8884b-387e-46f2-8dbf-c2e8ede87db5" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_3a6f0891-5bd1-466f-84e9-73373ba332ae" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost_3a6f0891-5bd1-466f-84e9-73373ba332ae" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_70690905-09e9-4e09-9fa5-fff7169dabfc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_NumberOfOperatingSegments_70690905-09e9-4e09-9fa5-fff7169dabfc" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_4a084ac3-3b91-430b-ae53-0e838a101e7a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_4a084ac3-3b91-430b-ae53-0e838a101e7a" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligation_1f8b9b6e-0e82-40f7-b4bf-c6f8d1e1149e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetRetirementObligation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_AssetRetirementObligation_1f8b9b6e-0e82-40f7-b4bf-c6f8d1e1149e" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_cc2bdc48-0d4e-43a1-a7dd-dfdba25da7f4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_cc2bdc48-0d4e-43a1-a7dd-dfdba25da7f4" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_a8b6530d-5598-47e6-84d8-9e5627c3a857" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_ee8419d4-3745-4e38-a9fa-abd3f4373b7e" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_a8b6530d-5598-47e6-84d8-9e5627c3a857" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_45edf4f5-b82a-4d9e-bd2a-164ace49bd68" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_a8b6530d-5598-47e6-84d8-9e5627c3a857" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_45edf4f5-b82a-4d9e-bd2a-164ace49bd68" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_45edf4f5-b82a-4d9e-bd2a-164ace49bd68_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_45edf4f5-b82a-4d9e-bd2a-164ace49bd68" xlink:to="loc_us-gaap_EquityComponentDomain_45edf4f5-b82a-4d9e-bd2a-164ace49bd68_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_62f58d86-85a5-4a36-9cf6-0ebfbc3d515f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_45edf4f5-b82a-4d9e-bd2a-164ace49bd68" xlink:to="loc_us-gaap_EquityComponentDomain_62f58d86-85a5-4a36-9cf6-0ebfbc3d515f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_0ecb0616-8cf8-47e7-ba03-fc97fff70ded" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_62f58d86-85a5-4a36-9cf6-0ebfbc3d515f" xlink:to="loc_us-gaap_RetainedEarningsMember_0ecb0616-8cf8-47e7-ba03-fc97fff70ded" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_a3d2ba2b-54d3-4b80-805f-b4daada80438" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_a8b6530d-5598-47e6-84d8-9e5627c3a857" xlink:to="loc_srt_RangeAxis_a3d2ba2b-54d3-4b80-805f-b4daada80438" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_a3d2ba2b-54d3-4b80-805f-b4daada80438_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_a3d2ba2b-54d3-4b80-805f-b4daada80438" xlink:to="loc_srt_RangeMember_a3d2ba2b-54d3-4b80-805f-b4daada80438_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_4de222fe-67f6-4527-8ff8-3814f17c57a0" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_a3d2ba2b-54d3-4b80-805f-b4daada80438" xlink:to="loc_srt_RangeMember_4de222fe-67f6-4527-8ff8-3814f17c57a0" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_0763190e-dad4-416f-8996-84f18c63354b" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_4de222fe-67f6-4527-8ff8-3814f17c57a0" xlink:to="loc_srt_MinimumMember_0763190e-dad4-416f-8996-84f18c63354b" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_3c7c237f-4cc4-4951-a808-806d5910e147" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_4de222fe-67f6-4527-8ff8-3814f17c57a0" xlink:to="loc_srt_MaximumMember_3c7c237f-4cc4-4951-a808-806d5910e147" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/CreditLosses" xlink:type="simple" xlink:href="ppg-20201231.xsd#CreditLosses"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CreditLosses" xlink:type="extended" id="i7fc1a61cb737461e9940887b27936ecc_CreditLosses"/>
<link:roleRef roleURI="http://www.ppg.com/role/CreditLossesTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#CreditLossesTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CreditLossesTables" xlink:type="extended" id="ifbcacb268fbd4d35a1a5219879ebc8ae_CreditLossesTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/CreditLossesDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#CreditLossesDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CreditLossesDetails" xlink:type="extended" id="ic74f49f612fb4e9da45993b131ca435a_CreditLossesDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/AcquisitionsandDispositions" xlink:type="simple" xlink:href="ppg-20201231.xsd#AcquisitionsandDispositions"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AcquisitionsandDispositions" xlink:type="extended" id="if5db52b1f5c2428d919eee34deec3b24_AcquisitionsandDispositions"/>
<link:roleRef roleURI="http://www.ppg.com/role/AcquisitionsandDispositionsTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#AcquisitionsandDispositionsTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AcquisitionsandDispositionsTables" xlink:type="extended" id="i94064f2138574517afe03a88162b70c9_AcquisitionsandDispositionsTables">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_81eea6f3-c597-4e1c-b68a-7576f39964d5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_31c0ef7d-3377-4e1d-9c74-6936ad8c3015" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_81eea6f3-c597-4e1c-b68a-7576f39964d5" xlink:to="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_31c0ef7d-3377-4e1d-9c74-6936ad8c3015" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1948b169-f293-4ac7-b942-a0cacd79063f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_81eea6f3-c597-4e1c-b68a-7576f39964d5" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1948b169-f293-4ac7-b942-a0cacd79063f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_f4c36d8e-9250-436e-886d-b4abfed8c7c4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_1948b169-f293-4ac7-b942-a0cacd79063f" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_f4c36d8e-9250-436e-886d-b4abfed8c7c4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_f4c36d8e-9250-436e-886d-b4abfed8c7c4_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_f4c36d8e-9250-436e-886d-b4abfed8c7c4" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_f4c36d8e-9250-436e-886d-b4abfed8c7c4_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_bae0c669-369a-4062-b86a-abf928583237" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_f4c36d8e-9250-436e-886d-b4abfed8c7c4" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_bae0c669-369a-4062-b86a-abf928583237" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_GlassSegmentMember_cac4bfcf-0ec3-4c15-9a88-d1820b12bf26" xlink:href="ppg-20201231.xsd#ppg_GlassSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_bae0c669-369a-4062-b86a-abf928583237" xlink:to="loc_ppg_GlassSegmentMember_cac4bfcf-0ec3-4c15-9a88-d1820b12bf26" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/AcquisitionsandDispositionsAcquistionsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#AcquisitionsandDispositionsAcquistionsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AcquisitionsandDispositionsAcquistionsDetail" xlink:type="extended" id="ic1e4904ff35645b5b67155b66277073f_AcquisitionsandDispositionsAcquistionsDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_70535cac-9cc6-492b-9a63-01a783b388de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfStores_68e330d4-cffa-4611-8a51-583f8b05989e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NumberOfStores"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_70535cac-9cc6-492b-9a63-01a783b388de" xlink:to="loc_us-gaap_NumberOfStores_68e330d4-cffa-4611-8a51-583f8b05989e" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ConsiderationPaidforAcquiredEntitiesNetofCashAcquiredDebtAssumedandOtherAdjustments_780383bc-ec37-4e72-8d1f-b8919936a9f3" xlink:href="ppg-20201231.xsd#ppg_ConsiderationPaidforAcquiredEntitiesNetofCashAcquiredDebtAssumedandOtherAdjustments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_70535cac-9cc6-492b-9a63-01a783b388de" xlink:to="loc_ppg_ConsiderationPaidforAcquiredEntitiesNetofCashAcquiredDebtAssumedandOtherAdjustments_780383bc-ec37-4e72-8d1f-b8919936a9f3" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_30ddf877-6904-4540-bab2-b684072725e3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_70535cac-9cc6-492b-9a63-01a783b388de" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_30ddf877-6904-4540-bab2-b684072725e3" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_7c86f127-ce6f-406f-855b-f1c99883db4c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_30ddf877-6904-4540-bab2-b684072725e3" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_7c86f127-ce6f-406f-855b-f1c99883db4c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_7c86f127-ce6f-406f-855b-f1c99883db4c_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_7c86f127-ce6f-406f-855b-f1c99883db4c" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_7c86f127-ce6f-406f-855b-f1c99883db4c_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ca0f946e-f844-4c4e-ab3c-ec29934a5d30" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_7c86f127-ce6f-406f-855b-f1c99883db4c" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ca0f946e-f844-4c4e-ab3c-ec29934a5d30" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ProCoatingsMember_c3af40b6-eca5-417d-8cf7-77dd2ba3aaf3" xlink:href="ppg-20201231.xsd#ppg_ProCoatingsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ca0f946e-f844-4c4e-ab3c-ec29934a5d30" xlink:to="loc_ppg_ProCoatingsMember_c3af40b6-eca5-417d-8cf7-77dd2ba3aaf3" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/AcquisitionsandDispositionsDivestituresMajorClassesofAssetsandLiabilitiesDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#AcquisitionsandDispositionsDivestituresMajorClassesofAssetsandLiabilitiesDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AcquisitionsandDispositionsDivestituresMajorClassesofAssetsandLiabilitiesDetails" xlink:type="extended" id="if0367bae82ef40ed8f6f5bd447635a16_AcquisitionsandDispositionsDivestituresMajorClassesofAssetsandLiabilitiesDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetImpairmentCharges_a3a81dd9-3bfb-4f56-89c6-f01a517654d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetImpairmentCharges"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_AssetImpairmentCharges_a3a81dd9-3bfb-4f56-89c6-f01a517654d6" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_9ef3cf6e-df82-4765-80e6-4c1f7b273fdc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_9ef3cf6e-df82-4765-80e6-4c1f7b273fdc" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet_97baaf92-a698-4cea-9b83-9d64961a6449" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet_97baaf92-a698-4cea-9b83-9d64961a6449" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent_510aa5ed-35f6-46cb-a80a-a8e99338a608" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent_510aa5ed-35f6-46cb-a80a-a8e99338a608" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_a212420d-49ae-43c0-bfcb-866d2c33eedc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_a212420d-49ae-43c0-bfcb-866d2c33eedc" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrent_66f2d30d-3d1a-4335-8216-f8d840bed793" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableAndAccruedLiabilitiesCurrent_66f2d30d-3d1a-4335-8216-f8d840bed793" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_a46747f8-a43d-45f0-80c5-7cf483b50b6a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_a46747f8-a43d-45f0-80c5-7cf483b50b6a" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilities_a715a80e-9ed5-4b4c-abd2-4f224bcd5453" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilities_a715a80e-9ed5-4b4c-abd2-4f224bcd5453" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherLiabilities_d76f3afa-eff4-447f-946d-90680fe7056b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherLiabilities_d76f3afa-eff4-447f-946d-90680fe7056b" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_790e16b7-9e95-473d-9620-c2798cf382e6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_790e16b7-9e95-473d-9620-c2798cf382e6" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_1dca8547-9619-4399-a42b-34ee78c38c08" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_61e80485-90c5-4eaa-bd64-70c613212231" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_1dca8547-9619-4399-a42b-34ee78c38c08" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_33c4180f-dfd8-4bd6-af38-506c346dccc6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_1dca8547-9619-4399-a42b-34ee78c38c08" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_33c4180f-dfd8-4bd6-af38-506c346dccc6" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_33c4180f-dfd8-4bd6-af38-506c346dccc6_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_33c4180f-dfd8-4bd6-af38-506c346dccc6" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_33c4180f-dfd8-4bd6-af38-506c346dccc6_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_e37a3cb1-3562-4437-91b0-798034b71a3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupClassificationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_33c4180f-dfd8-4bd6-af38-506c346dccc6" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_e37a3cb1-3562-4437-91b0-798034b71a3c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember_4c229fb4-a45c-4298-b0ba-4eb81263b9ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_e37a3cb1-3562-4437-91b0-798034b71a3c" xlink:to="loc_us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember_4c229fb4-a45c-4298-b0ba-4eb81263b9ee" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/AcquisitionsandDispositionsDivestituresGlassSegmentDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#AcquisitionsandDispositionsDivestituresGlassSegmentDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AcquisitionsandDispositionsDivestituresGlassSegmentDetails" xlink:type="extended" id="ie10fc8c2c8a7479bb16ecc033e987d93_AcquisitionsandDispositionsDivestituresGlassSegmentDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_b18bec21-d5aa-4267-9a97-518123c72de1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResultsOfOperationsIncomeBeforeIncomeTaxes_47b54b95-463a-4eab-bb5b-0d5690aedaf7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResultsOfOperationsIncomeBeforeIncomeTaxes"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_b18bec21-d5aa-4267-9a97-518123c72de1" xlink:to="loc_us-gaap_ResultsOfOperationsIncomeBeforeIncomeTaxes_47b54b95-463a-4eab-bb5b-0d5690aedaf7" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_9cf63710-22fa-421d-8751-c8498e1f0bea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_b18bec21-d5aa-4267-9a97-518123c72de1" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_9cf63710-22fa-421d-8751-c8498e1f0bea" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_9b0ac28e-cf22-4d77-8a96-8a91e273854a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_b18bec21-d5aa-4267-9a97-518123c72de1" xlink:to="loc_us-gaap_NetIncomeLoss_9b0ac28e-cf22-4d77-8a96-8a91e273854a" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_776f144a-ec1e-4023-a7c2-8913db513610" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_b18bec21-d5aa-4267-9a97-518123c72de1" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_776f144a-ec1e-4023-a7c2-8913db513610" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations_36610791-3584-441d-9600-3a22292096a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_b18bec21-d5aa-4267-9a97-518123c72de1" xlink:to="loc_us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations_36610791-3584-441d-9600-3a22292096a3" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_df8e020d-b4b3-4a2c-9dd6-2334ad577f84" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_b18bec21-d5aa-4267-9a97-518123c72de1" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_df8e020d-b4b3-4a2c-9dd6-2334ad577f84" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_0c063fce-bcfe-4971-ad01-3ffc84a6de70" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_df8e020d-b4b3-4a2c-9dd6-2334ad577f84" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_0c063fce-bcfe-4971-ad01-3ffc84a6de70" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0c063fce-bcfe-4971-ad01-3ffc84a6de70_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_0c063fce-bcfe-4971-ad01-3ffc84a6de70" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0c063fce-bcfe-4971-ad01-3ffc84a6de70_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_21c5b518-52b1-45b0-b0bd-3462f88a3fa3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_0c063fce-bcfe-4971-ad01-3ffc84a6de70" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_21c5b518-52b1-45b0-b0bd-3462f88a3fa3" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_GlassSegmentMember_2f28e172-b209-4d18-9a8c-e9bcb460aee1" xlink:href="ppg-20201231.xsd#ppg_GlassSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_21c5b518-52b1-45b0-b0bd-3462f88a3fa3" xlink:to="loc_ppg_GlassSegmentMember_2f28e172-b209-4d18-9a8c-e9bcb460aee1" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/WorkingCapitalDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#WorkingCapitalDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/WorkingCapitalDetail" xlink:type="extended" id="i0f2c026ff803450581fdb81c7d7a0448_WorkingCapitalDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/WorkingCapitalDetailTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#WorkingCapitalDetailTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/WorkingCapitalDetailTables" xlink:type="extended" id="ie3da40f6bd5d41d28ac95801a3ac54ab_WorkingCapitalDetailTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/WorkingCapitalDetailDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#WorkingCapitalDetailDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/WorkingCapitalDetailDetail" xlink:type="extended" id="i90b16f63291b43ec894cf9730730622e_WorkingCapitalDetailDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/WorkingCapitalDetailAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#WorkingCapitalDetailAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/WorkingCapitalDetailAdditionalInformationDetail" xlink:type="extended" id="i3cc52316df734c8da75eb059aa8be7a0_WorkingCapitalDetailAdditionalInformationDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/PropertyPlantandEquipment" xlink:type="simple" xlink:href="ppg-20201231.xsd#PropertyPlantandEquipment"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/PropertyPlantandEquipment" xlink:type="extended" id="if50e40d4cc9a4246bf4e099a628ca8fe_PropertyPlantandEquipment"/>
<link:roleRef roleURI="http://www.ppg.com/role/PropertyPlantandEquipmentTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#PropertyPlantandEquipmentTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/PropertyPlantandEquipmentTables" xlink:type="extended" id="i0e44c68d230e4fe9aff635e35d4ede3b_PropertyPlantandEquipmentTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/PropertyPlantandEquipmentDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#PropertyPlantandEquipmentDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/PropertyPlantandEquipmentDetail" xlink:type="extended" id="i0a2fdaf1ecdc41d994d8927ce15ff65c_PropertyPlantandEquipmentDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_fda4178e-b0f8-4ace-9611-86ff960aca9d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_1fad3320-1193-4607-a9fd-b7558e7514fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_fda4178e-b0f8-4ace-9611-86ff960aca9d" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_1fad3320-1193-4607-a9fd-b7558e7514fd" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_33515305-a56d-42f2-81db-55baea2e4dcc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_fda4178e-b0f8-4ace-9611-86ff960aca9d" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_33515305-a56d-42f2-81db-55baea2e4dcc" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_78f2800c-27d2-4b13-a6ca-2acdc6ea91f7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_fda4178e-b0f8-4ace-9611-86ff960aca9d" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_78f2800c-27d2-4b13-a6ca-2acdc6ea91f7" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_32e510e9-4d6c-494b-945a-bbaf2ea6d519" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_fda4178e-b0f8-4ace-9611-86ff960aca9d" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_32e510e9-4d6c-494b-945a-bbaf2ea6d519" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestCostsCapitalized_e79f4870-f85a-4d79-987d-a82f3de1a4b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestCostsCapitalized"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_fda4178e-b0f8-4ace-9611-86ff960aca9d" xlink:to="loc_us-gaap_InterestCostsCapitalized_e79f4870-f85a-4d79-987d-a82f3de1a4b0" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_1b2f1c6d-87b1-459c-8294-547a488c6f7b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_fda4178e-b0f8-4ace-9611-86ff960aca9d" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_1b2f1c6d-87b1-459c-8294-547a488c6f7b" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_65f8b212-04a2-40f1-8834-598dc29e9ee2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_1b2f1c6d-87b1-459c-8294-547a488c6f7b" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_65f8b212-04a2-40f1-8834-598dc29e9ee2" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_65f8b212-04a2-40f1-8834-598dc29e9ee2_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_65f8b212-04a2-40f1-8834-598dc29e9ee2" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_65f8b212-04a2-40f1-8834-598dc29e9ee2_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3652d3df-7dea-416f-8527-ff2a43ddc6c3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_65f8b212-04a2-40f1-8834-598dc29e9ee2" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3652d3df-7dea-416f-8527-ff2a43ddc6c3" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LandAndLandImprovementsMember_18206afd-92fa-4726-81a8-6995257b6765" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LandAndLandImprovementsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3652d3df-7dea-416f-8527-ff2a43ddc6c3" xlink:to="loc_us-gaap_LandAndLandImprovementsMember_18206afd-92fa-4726-81a8-6995257b6765" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BuildingMember_c5a1a8cb-a54c-4268-b3c7-3e3f02ce4e15" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BuildingMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3652d3df-7dea-416f-8527-ff2a43ddc6c3" xlink:to="loc_us-gaap_BuildingMember_c5a1a8cb-a54c-4268-b3c7-3e3f02ce4e15" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MachineryAndEquipmentMember_a67a196d-5585-4e12-ba37-9122d54a1913" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MachineryAndEquipmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3652d3df-7dea-416f-8527-ff2a43ddc6c3" xlink:to="loc_us-gaap_MachineryAndEquipmentMember_a67a196d-5585-4e12-ba37-9122d54a1913" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentOtherTypesMember_34ec14c2-dbe0-4fd6-884f-d9c6a09ce346" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentOtherTypesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3652d3df-7dea-416f-8527-ff2a43ddc6c3" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentOtherTypesMember_34ec14c2-dbe0-4fd6-884f-d9c6a09ce346" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionInProgressMember_a01a78c8-f56e-4308-9415-8e8b2870c986" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConstructionInProgressMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3652d3df-7dea-416f-8527-ff2a43ddc6c3" xlink:to="loc_us-gaap_ConstructionInProgressMember_a01a78c8-f56e-4308-9415-8e8b2870c986" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_a602657a-cbda-48b9-b44e-17b48e65daf6" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_1b2f1c6d-87b1-459c-8294-547a488c6f7b" xlink:to="loc_srt_RangeAxis_a602657a-cbda-48b9-b44e-17b48e65daf6" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_a602657a-cbda-48b9-b44e-17b48e65daf6_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_a602657a-cbda-48b9-b44e-17b48e65daf6" xlink:to="loc_srt_RangeMember_a602657a-cbda-48b9-b44e-17b48e65daf6_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_37f15eba-3396-4dc3-90bd-7aa0740b37ce" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_a602657a-cbda-48b9-b44e-17b48e65daf6" xlink:to="loc_srt_RangeMember_37f15eba-3396-4dc3-90bd-7aa0740b37ce" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_99a37600-3275-4c48-83e6-b5fce966099f" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_37f15eba-3396-4dc3-90bd-7aa0740b37ce" xlink:to="loc_srt_MinimumMember_99a37600-3275-4c48-83e6-b5fce966099f" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_6207f55e-db92-494e-bb5e-81d5e1ea1b60" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_37f15eba-3396-4dc3-90bd-7aa0740b37ce" xlink:to="loc_srt_MaximumMember_6207f55e-db92-494e-bb5e-81d5e1ea1b60" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/Investments" xlink:type="simple" xlink:href="ppg-20201231.xsd#Investments"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/Investments" xlink:type="extended" id="icbedce495631489ba053c22843b0e592_Investments"/>
<link:roleRef roleURI="http://www.ppg.com/role/InvestmentsTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#InvestmentsTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/InvestmentsTables" xlink:type="extended" id="i87dfdbefb4f64596a5cb4823910018f5_InvestmentsTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/InvestmentsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#InvestmentsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/InvestmentsDetail" xlink:type="extended" id="ia44aecdc2af74de7bda282d2b9390797_InvestmentsDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsLineItems_2cebb24b-287a-43fd-9db5-838eba74e772" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermInvestments_76e5a137-4815-451a-82a9-ebae521d4efa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermInvestments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsLineItems_2cebb24b-287a-43fd-9db5-838eba74e772" xlink:to="loc_us-gaap_LongTermInvestments_76e5a137-4815-451a-82a9-ebae521d4efa" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PercentageOfOwnershipInterests_0dad9ba9-dded-4ddc-a6e9-39de3e3571f0" xlink:href="ppg-20201231.xsd#ppg_PercentageOfOwnershipInterests"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsLineItems_2cebb24b-287a-43fd-9db5-838eba74e772" xlink:to="loc_ppg_PercentageOfOwnershipInterests_0dad9ba9-dded-4ddc-a6e9-39de3e3571f0" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_EquityInUndistributedEarningsLossesOfSubsidiaries_8a62351d-00f8-49ca-89dc-e95f048e5d6c" xlink:href="ppg-20201231.xsd#ppg_EquityInUndistributedEarningsLossesOfSubsidiaries"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsLineItems_2cebb24b-287a-43fd-9db5-838eba74e772" xlink:to="loc_ppg_EquityInUndistributedEarningsLossesOfSubsidiaries_8a62351d-00f8-49ca-89dc-e95f048e5d6c" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromDividendsReceived_be2b5c7f-d36e-46cb-abe7-e00ad08e1d30" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromDividendsReceived"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsLineItems_2cebb24b-287a-43fd-9db5-838eba74e772" xlink:to="loc_us-gaap_ProceedsFromDividendsReceived_be2b5c7f-d36e-46cb-abe7-e00ad08e1d30" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsTable_5f25ae70-3a32-4417-8d68-c7a9a5249697" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsLineItems_2cebb24b-287a-43fd-9db5-838eba74e772" xlink:to="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsTable_5f25ae70-3a32-4417-8d68-c7a9a5249697" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_8f838479-95d2-4011-ab06-fe412c0677ed" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsTable_5f25ae70-3a32-4417-8d68-c7a9a5249697" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_8f838479-95d2-4011-ab06-fe412c0677ed" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_8f838479-95d2-4011-ab06-fe412c0677ed_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_EquityMethodInvesteeNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_8f838479-95d2-4011-ab06-fe412c0677ed" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_8f838479-95d2-4011-ab06-fe412c0677ed_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_8ba47a70-1022-46c3-aeab-3c7a75ddc089" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_EquityMethodInvesteeNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_8f838479-95d2-4011-ab06-fe412c0677ed" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_8ba47a70-1022-46c3-aeab-3c7a75ddc089" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_InvestmentsInOtherOperatingJointVenturesMember_b3b7e3d0-8bf7-49fb-a46e-3312c1d37c01" xlink:href="ppg-20201231.xsd#ppg_InvestmentsInOtherOperatingJointVenturesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_8ba47a70-1022-46c3-aeab-3c7a75ddc089" xlink:to="loc_ppg_InvestmentsInOtherOperatingJointVenturesMember_b3b7e3d0-8bf7-49fb-a46e-3312c1d37c01" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_7fdd00a9-ca34-4af8-9d58-7340b793b9ce" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsTable_5f25ae70-3a32-4417-8d68-c7a9a5249697" xlink:to="loc_srt_RangeAxis_7fdd00a9-ca34-4af8-9d58-7340b793b9ce" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_7fdd00a9-ca34-4af8-9d58-7340b793b9ce_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_7fdd00a9-ca34-4af8-9d58-7340b793b9ce" xlink:to="loc_srt_RangeMember_7fdd00a9-ca34-4af8-9d58-7340b793b9ce_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_abb6b6bf-f4cf-4a03-88a5-6008608ecb96" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_7fdd00a9-ca34-4af8-9d58-7340b793b9ce" xlink:to="loc_srt_RangeMember_abb6b6bf-f4cf-4a03-88a5-6008608ecb96" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_7b866582-f8e1-4b80-85db-bb2f363692eb" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_abb6b6bf-f4cf-4a03-88a5-6008608ecb96" xlink:to="loc_srt_MinimumMember_7b866582-f8e1-4b80-85db-bb2f363692eb" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_2f98ce09-8dbb-47bd-a424-1f20a70ad16e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_abb6b6bf-f4cf-4a03-88a5-6008608ecb96" xlink:to="loc_srt_MaximumMember_2f98ce09-8dbb-47bd-a424-1f20a70ad16e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis_7476c451-1e9b-4fe8-98cc-2a16acc7e374" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsTable_5f25ae70-3a32-4417-8d68-c7a9a5249697" xlink:to="loc_us-gaap_InvestmentTypeAxis_7476c451-1e9b-4fe8-98cc-2a16acc7e374" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_7476c451-1e9b-4fe8-98cc-2a16acc7e374_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_InvestmentTypeAxis_7476c451-1e9b-4fe8-98cc-2a16acc7e374" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_7476c451-1e9b-4fe8-98cc-2a16acc7e374_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_a55d1c66-7a56-49a1-9212-a93d48d60904" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_InvestmentTypeAxis_7476c451-1e9b-4fe8-98cc-2a16acc7e374" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_a55d1c66-7a56-49a1-9212-a93d48d60904" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_InvestmentsInAndAdvancesToAffiliatesMember_2669c3cd-8800-429f-9842-6e7721b8ce46" xlink:href="ppg-20201231.xsd#ppg_InvestmentsInAndAdvancesToAffiliatesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_a55d1c66-7a56-49a1-9212-a93d48d60904" xlink:to="loc_ppg_InvestmentsInAndAdvancesToAffiliatesMember_2669c3cd-8800-429f-9842-6e7721b8ce46" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_MarketableSecuritiesMember_506568f2-531c-420b-b815-0a797d92e7f4" xlink:href="ppg-20201231.xsd#ppg_MarketableSecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_a55d1c66-7a56-49a1-9212-a93d48d60904" xlink:to="loc_ppg_MarketableSecuritiesMember_506568f2-531c-420b-b815-0a797d92e7f4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherInvestmentsMember_1a8e17c4-4c62-4e66-8c0b-3830706adefc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherInvestmentsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_a55d1c66-7a56-49a1-9212-a93d48d60904" xlink:to="loc_us-gaap_OtherInvestmentsMember_1a8e17c4-4c62-4e66-8c0b-3830706adefc" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_f9f71df0-f845-4f3b-81db-03a5fc77d7b6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfTradingSecuritiesAndOtherTradingAssetsTable_5f25ae70-3a32-4417-8d68-c7a9a5249697" xlink:to="loc_us-gaap_FinancialInstrumentAxis_f9f71df0-f845-4f3b-81db-03a5fc77d7b6" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_f9f71df0-f845-4f3b-81db-03a5fc77d7b6_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FinancialInstrumentAxis_f9f71df0-f845-4f3b-81db-03a5fc77d7b6" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_f9f71df0-f845-4f3b-81db-03a5fc77d7b6_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_d08875f7-1d49-4ce8-b442-12c10cef1a2a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FinancialInstrumentAxis_f9f71df0-f845-4f3b-81db-03a5fc77d7b6" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_d08875f7-1d49-4ce8-b442-12c10cef1a2a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_TradingSecuritiesMember_41479225-825a-4868-a4f3-cfb5227fdf81" xlink:href="ppg-20201231.xsd#ppg_TradingSecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_d08875f7-1d49-4ce8-b442-12c10cef1a2a" xlink:to="loc_ppg_TradingSecuritiesMember_41479225-825a-4868-a4f3-cfb5227fdf81" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssets" xlink:type="simple" xlink:href="ppg-20201231.xsd#GoodwillandOtherIdentifiableIntangibleAssets"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssets" xlink:type="extended" id="i2e22349a573c4819928588d98d8ee5fe_GoodwillandOtherIdentifiableIntangibleAssets"/>
<link:roleRef roleURI="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssetsTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#GoodwillandOtherIdentifiableIntangibleAssetsTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssetsTables" xlink:type="extended" id="if3f5d62bb0a046e89daca671b0e3dfa9_GoodwillandOtherIdentifiableIntangibleAssetsTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssetsCarryingAmountofGoodwillAttributabletoEachReportableSegmentDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#GoodwillandOtherIdentifiableIntangibleAssetsCarryingAmountofGoodwillAttributabletoEachReportableSegmentDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssetsCarryingAmountofGoodwillAttributabletoEachReportableSegmentDetail" xlink:type="extended" id="i209eb279cc6d44f087b526504bdccf07_GoodwillandOtherIdentifiableIntangibleAssetsCarryingAmountofGoodwillAttributabletoEachReportableSegmentDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillLineItems_3ca5570c-3ea7-4672-b901-dae7bed01bff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillRollForward_346561c4-e0da-47a1-bdc4-ed5e5234fd8d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_3ca5570c-3ea7-4672-b901-dae7bed01bff" xlink:to="loc_us-gaap_GoodwillRollForward_346561c4-e0da-47a1-bdc4-ed5e5234fd8d" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_5949a6ff-88dc-4d7b-85e5-3ea69a71012f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_346561c4-e0da-47a1-bdc4-ed5e5234fd8d" xlink:to="loc_us-gaap_Goodwill_5949a6ff-88dc-4d7b-85e5-3ea69a71012f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAcquiredDuringPeriod_b32c6b3e-2fea-461d-b4db-0497f85d957b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAcquiredDuringPeriod"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_346561c4-e0da-47a1-bdc4-ed5e5234fd8d" xlink:to="loc_us-gaap_GoodwillAcquiredDuringPeriod_b32c6b3e-2fea-461d-b4db-0497f85d957b" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_ea9982d2-b17a-466f-b06b-330cf9ba9ceb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillImpairmentLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_346561c4-e0da-47a1-bdc4-ed5e5234fd8d" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_ea9982d2-b17a-466f-b06b-330cf9ba9ceb" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments_5412849d-e3c0-4f35-b467-3ce7a0c3b8cb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_346561c4-e0da-47a1-bdc4-ed5e5234fd8d" xlink:to="loc_us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments_5412849d-e3c0-4f35-b467-3ce7a0c3b8cb" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_0dc69fbd-ede8-490c-a850-fec5d59f5264" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_c0c2ad2b-3a2f-4058-a002-7b9a73386c44" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfGoodwillTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_GoodwillLineItems_3ca5570c-3ea7-4672-b901-dae7bed01bff" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_c0c2ad2b-3a2f-4058-a002-7b9a73386c44" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_452deaed-2dac-4da6-ae2f-44fd86f43264" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_c0c2ad2b-3a2f-4058-a002-7b9a73386c44" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_452deaed-2dac-4da6-ae2f-44fd86f43264" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_452deaed-2dac-4da6-ae2f-44fd86f43264_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_452deaed-2dac-4da6-ae2f-44fd86f43264" xlink:to="loc_us-gaap_SegmentDomain_452deaed-2dac-4da6-ae2f-44fd86f43264_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_074e84ce-29e1-4833-acdc-02a30398e6fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_452deaed-2dac-4da6-ae2f-44fd86f43264" xlink:to="loc_us-gaap_SegmentDomain_074e84ce-29e1-4833-acdc-02a30398e6fd" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PerformanceCoatingsSegmentMember_30fb63f2-ee6c-4c34-9de8-f4bdcde19e88" xlink:href="ppg-20201231.xsd#ppg_PerformanceCoatingsSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_074e84ce-29e1-4833-acdc-02a30398e6fd" xlink:to="loc_ppg_PerformanceCoatingsSegmentMember_30fb63f2-ee6c-4c34-9de8-f4bdcde19e88" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IndustrialCoatingsSegmentMember_dcb9105b-d4e6-420a-aec8-9d8a49e880a0" xlink:href="ppg-20201231.xsd#ppg_IndustrialCoatingsSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_074e84ce-29e1-4833-acdc-02a30398e6fd" xlink:to="loc_ppg_IndustrialCoatingsSegmentMember_dcb9105b-d4e6-420a-aec8-9d8a49e880a0" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssetsIdentifiableIntangibleAssetswithFiniteLivesDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#GoodwillandOtherIdentifiableIntangibleAssetsIdentifiableIntangibleAssetswithFiniteLivesDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/GoodwillandOtherIdentifiableIntangibleAssetsIdentifiableIntangibleAssetswithFiniteLivesDetail" xlink:type="extended" id="i604aa76b79ed4a5a9081faf4885f27f1_GoodwillandOtherIdentifiableIntangibleAssetsIdentifiableIntangibleAssetswithFiniteLivesDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedTrademarks_2aaa29c0-f53a-460b-aeab-c4b93a0d81d9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IndefiniteLivedTrademarks"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_IndefiniteLivedTrademarks_2aaa29c0-f53a-460b-aeab-c4b93a0d81d9" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_36f4eee4-a840-48bd-9971-b382e61dfc5d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_36f4eee4-a840-48bd-9971-b382e61dfc5d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_71a0ac8a-428c-4169-869f-01c78f29eba5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_71a0ac8a-428c-4169-869f-01c78f29eba5" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_4d5681ca-66a3-4fcb-9f2d-b0f808c34027" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_4d5681ca-66a3-4fcb-9f2d-b0f808c34027" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_5a4febe2-78ed-4e21-bc20-ea72fe7f2d9b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_5a4febe2-78ed-4e21-bc20-ea72fe7f2d9b" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IntangibleAssetsAccumulatedAmortizationExcludingGoodwill_f44e98dc-ab61-40f0-8fa9-9c9ae5ba8a22" xlink:href="ppg-20201231.xsd#ppg_IntangibleAssetsAccumulatedAmortizationExcludingGoodwill"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_ppg_IntangibleAssetsAccumulatedAmortizationExcludingGoodwill_f44e98dc-ab61-40f0-8fa9-9c9ae5ba8a22" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_d4d1e358-8cf1-465b-b38d-b91b1e38e5a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_d4d1e358-8cf1-465b-b38d-b91b1e38e5a8" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairedIntangibleAssetDescription_9cf0e0be-3d99-4c90-90af-a789c1a9fad6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairedIntangibleAssetDescription"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_ImpairedIntangibleAssetDescription_9cf0e0be-3d99-4c90-90af-a789c1a9fad6" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5276321c-6365-4f49-b2b8-a9eedd59bf12" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5276321c-6365-4f49-b2b8-a9eedd59bf12" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_ae080555-54ae-43ff-83d4-65968f93e428" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_ae080555-54ae-43ff-83d4-65968f93e428" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_74563e9a-ee44-47f4-9677-5ea378c6f43a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_74563e9a-ee44-47f4-9677-5ea378c6f43a" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_e161b529-fffa-4f62-9d53-6a055f16f566" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_e161b529-fffa-4f62-9d53-6a055f16f566" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_4e43d2c8-79f2-490d-83f3-f81e9d522a44" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_4e43d2c8-79f2-490d-83f3-f81e9d522a44" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_e0274502-5d5e-4968-9df5-ce3eace93128" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_e0274502-5d5e-4968-9df5-ce3eace93128" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_383ad187-b878-43fe-90b3-410b1c44d436" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_383ad187-b878-43fe-90b3-410b1c44d436" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_060f99d9-9240-4ef5-818a-c46849d86194" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_70263883-598c-41d8-98dc-e6af624be09f" xlink:to="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_060f99d9-9240-4ef5-818a-c46849d86194" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_21ed1b17-b2e0-4be3-805d-ad30573411dc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_060f99d9-9240-4ef5-818a-c46849d86194" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_21ed1b17-b2e0-4be3-805d-ad30573411dc" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_21ed1b17-b2e0-4be3-805d-ad30573411dc_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_21ed1b17-b2e0-4be3-805d-ad30573411dc" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_21ed1b17-b2e0-4be3-805d-ad30573411dc_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_647be019-74ca-4929-94c1-2aef6d2db79d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_21ed1b17-b2e0-4be3-805d-ad30573411dc" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_647be019-74ca-4929-94c1-2aef6d2db79d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember_9f4fba0c-6648-4aab-a71c-bed20976c8eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_647be019-74ca-4929-94c1-2aef6d2db79d" xlink:to="loc_us-gaap_DevelopedTechnologyRightsMember_9f4fba0c-6648-4aab-a71c-bed20976c8eb" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerRelationshipsMember_032fa99d-f760-40fa-b309-f952b914a12f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CustomerRelationshipsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_647be019-74ca-4929-94c1-2aef6d2db79d" xlink:to="loc_us-gaap_CustomerRelationshipsMember_032fa99d-f760-40fa-b309-f952b914a12f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TradeNamesMember_311ee5cd-ad54-499f-bf01-8d1488b38778" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TradeNamesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_647be019-74ca-4929-94c1-2aef6d2db79d" xlink:to="loc_us-gaap_TradeNamesMember_311ee5cd-ad54-499f-bf01-8d1488b38778" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIntangibleAssetsMember_898fd4b8-a675-4453-a139-6b64ee980311" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherIntangibleAssetsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_647be019-74ca-4929-94c1-2aef6d2db79d" xlink:to="loc_us-gaap_OtherIntangibleAssetsMember_898fd4b8-a675-4453-a139-6b64ee980311" xlink:type="arc" order="3"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/BusinessRestructuring" xlink:type="simple" xlink:href="ppg-20201231.xsd#BusinessRestructuring"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BusinessRestructuring" xlink:type="extended" id="i49a6312593274a27aef01431caf76c22_BusinessRestructuring"/>
<link:roleRef roleURI="http://www.ppg.com/role/BusinessRestructuringTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#BusinessRestructuringTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BusinessRestructuringTables" xlink:type="extended" id="i8529835acc3f4acf9920eb232089c20d_BusinessRestructuringTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/BusinessRestructuringAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#BusinessRestructuringAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BusinessRestructuringAdditionalInformationDetail" xlink:type="extended" id="i804416d90c584687b8f0522e1479891c_BusinessRestructuringAdditionalInformationDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_95082af7-8cd1-40e4-a6a7-06ff4a1f7c7b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanCurtailmentsAndSettlements_8e209889-9837-407f-bb1c-569252e6d9d4" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanCurtailmentsAndSettlements"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_95082af7-8cd1-40e4-a6a7-06ff4a1f7c7b" xlink:to="loc_ppg_DefinedBenefitPlanCurtailmentsAndSettlements_8e209889-9837-407f-bb1c-569252e6d9d4" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringReserveRollForward_6e058084-7a05-4529-85d5-e6581691f644" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_95082af7-8cd1-40e4-a6a7-06ff4a1f7c7b" xlink:to="loc_us-gaap_RestructuringReserveRollForward_6e058084-7a05-4529-85d5-e6581691f644" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringReserve_5cb39489-69d5-4456-90ab-d905745b68ba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserve"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_6e058084-7a05-4529-85d5-e6581691f644" xlink:to="loc_us-gaap_RestructuringReserve_5cb39489-69d5-4456-90ab-d905745b68ba" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringCharges_e93b498e-66ec-46f6-ab3f-d6cd317dec00" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCharges"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_6e058084-7a05-4529-85d5-e6581691f644" xlink:to="loc_us-gaap_RestructuringCharges_e93b498e-66ec-46f6-ab3f-d6cd317dec00" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringReserveAccrualAdjustment1_c536ff9d-a3e6-4448-a28f-84d6bc9787d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveAccrualAdjustment1"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_6e058084-7a05-4529-85d5-e6581691f644" xlink:to="loc_us-gaap_RestructuringReserveAccrualAdjustment1_c536ff9d-a3e6-4448-a28f-84d6bc9787d6" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRestructuring_2b3d6380-871f-4df3-909f-9764e9a274b9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForRestructuring"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_6e058084-7a05-4529-85d5-e6581691f644" xlink:to="loc_us-gaap_PaymentsForRestructuring_2b3d6380-871f-4df3-909f-9764e9a274b9" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringReserveTranslationAdjustment_651ab153-da2b-42f8-aeff-11fb88e80474" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserveTranslationAdjustment"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_6e058084-7a05-4529-85d5-e6581691f644" xlink:to="loc_us-gaap_RestructuringReserveTranslationAdjustment_651ab153-da2b-42f8-aeff-11fb88e80474" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringReserve_6ead37b3-66b6-4988-bae9-dde31d6b5127" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringReserve"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_c456afc2-ae96-4673-ab6a-3cd93f6ab3de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_95082af7-8cd1-40e4-a6a7-06ff4a1f7c7b" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_c456afc2-ae96-4673-ab6a-3cd93f6ab3de" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_14a7ad54-76ca-4d6f-867d-38109f9c2a35" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_c456afc2-ae96-4673-ab6a-3cd93f6ab3de" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_14a7ad54-76ca-4d6f-867d-38109f9c2a35" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_14a7ad54-76ca-4d6f-867d-38109f9c2a35_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_14a7ad54-76ca-4d6f-867d-38109f9c2a35" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_14a7ad54-76ca-4d6f-867d-38109f9c2a35_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_82813759-dc19-4da6-a102-acfa9a839ff4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_14a7ad54-76ca-4d6f-867d-38109f9c2a35" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_82813759-dc19-4da6-a102-acfa9a839ff4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringChargesMember_9834e9ce-09b4-48ca-9644-0e93d1532592" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringChargesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_82813759-dc19-4da6-a102-acfa9a839ff4" xlink:to="loc_us-gaap_RestructuringChargesMember_9834e9ce-09b4-48ca-9644-0e93d1532592" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringPlanAxis_ab4fc755-1ba2-46d1-b513-f05b6c54085d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringPlanAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_c456afc2-ae96-4673-ab6a-3cd93f6ab3de" xlink:to="loc_us-gaap_RestructuringPlanAxis_ab4fc755-1ba2-46d1-b513-f05b6c54085d" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringPlanDomain_ab4fc755-1ba2-46d1-b513-f05b6c54085d_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringPlanDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RestructuringPlanAxis_ab4fc755-1ba2-46d1-b513-f05b6c54085d" xlink:to="loc_us-gaap_RestructuringPlanDomain_ab4fc755-1ba2-46d1-b513-f05b6c54085d_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringPlanDomain_64e112f7-7e2a-4133-8b24-8ddca51611f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringPlanDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RestructuringPlanAxis_ab4fc755-1ba2-46d1-b513-f05b6c54085d" xlink:to="loc_us-gaap_RestructuringPlanDomain_64e112f7-7e2a-4133-8b24-8ddca51611f2" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A2019RestructuringProgramMember_728dadba-25e1-401b-82c6-584e8d0dc6b0" xlink:href="ppg-20201231.xsd#ppg_A2019RestructuringProgramMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringPlanDomain_64e112f7-7e2a-4133-8b24-8ddca51611f2" xlink:to="loc_ppg_A2019RestructuringProgramMember_728dadba-25e1-401b-82c6-584e8d0dc6b0" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationAxis_4e1a27ba-5ddd-4283-a38f-80e21e6707fa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_c456afc2-ae96-4673-ab6a-3cd93f6ab3de" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationAxis_4e1a27ba-5ddd-4283-a38f-80e21e6707fa" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_4e1a27ba-5ddd-4283-a38f-80e21e6707fa_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_4e1a27ba-5ddd-4283-a38f-80e21e6707fa" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_4e1a27ba-5ddd-4283-a38f-80e21e6707fa_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_b4642519-66fd-4151-a512-6c1dd2a75213" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_4e1a27ba-5ddd-4283-a38f-80e21e6707fa" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_b4642519-66fd-4151-a512-6c1dd2a75213" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticPlanMember_80fcd98a-f9da-4ff0-a2bc-ff5a2967b003" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_b4642519-66fd-4151-a512-6c1dd2a75213" xlink:to="loc_us-gaap_DomesticPlanMember_80fcd98a-f9da-4ff0-a2bc-ff5a2967b003" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_country_US_f40b1dd6-c951-421c-bbcc-964c71177863" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_US"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DomesticPlanMember_80fcd98a-f9da-4ff0-a2bc-ff5a2967b003" xlink:to="loc_country_US_f40b1dd6-c951-421c-bbcc-964c71177863" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_65f2a2cf-345c-4939-9f2f-8ada5c16b927" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_c456afc2-ae96-4673-ab6a-3cd93f6ab3de" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_65f2a2cf-345c-4939-9f2f-8ada5c16b927" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_65f2a2cf-345c-4939-9f2f-8ada5c16b927_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_65f2a2cf-345c-4939-9f2f-8ada5c16b927" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_65f2a2cf-345c-4939-9f2f-8ada5c16b927_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_b39f5a19-d5d0-4553-a82f-bdbd880f9109" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_65f2a2cf-345c-4939-9f2f-8ada5c16b927" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_b39f5a19-d5d0-4553-a82f-bdbd880f9109" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_e086ad06-7fd2-4cbc-9550-067b7971220c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_b39f5a19-d5d0-4553-a82f-bdbd880f9109" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_e086ad06-7fd2-4cbc-9550-067b7971220c" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/Leases" xlink:type="simple" xlink:href="ppg-20201231.xsd#Leases"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/Leases" xlink:type="extended" id="i8135487c6c2d4c9ba311bbad6363c650_Leases"/>
<link:roleRef roleURI="http://www.ppg.com/role/LeasesTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#LeasesTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/LeasesTables" xlink:type="extended" id="if42f2a1804704064985af8e87c54fe68_LeasesTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/LeasesScheduleofComponentsofLeaseExpenseDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#LeasesScheduleofComponentsofLeaseExpenseDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/LeasesScheduleofComponentsofLeaseExpenseDetails" xlink:type="extended" id="ia7a54f515e1d485a892d1d07840e61f2_LeasesScheduleofComponentsofLeaseExpenseDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_b6ca121f-a08e-4945-9d30-4ff5ddca99ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_245fc05e-d4c6-41d9-b372-ab48d1d31770" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_b6ca121f-a08e-4945-9d30-4ff5ddca99ce" xlink:to="loc_us-gaap_OperatingLeaseCost_245fc05e-d4c6-41d9-b372-ab48d1d31770" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCostAbstract_32129260-5868-4fe0-99bc-c588e9b94233" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeaseCostAbstract"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_b6ca121f-a08e-4945-9d30-4ff5ddca99ce" xlink:to="loc_us-gaap_LeaseCostAbstract_32129260-5868-4fe0-99bc-c588e9b94233" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseInterestExpense_d64e0aa3-c6eb-4b0a-8d47-fe2e47e68801" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseInterestExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LeaseCostAbstract_32129260-5868-4fe0-99bc-c588e9b94233" xlink:to="loc_us-gaap_FinanceLeaseInterestExpense_d64e0aa3-c6eb-4b0a-8d47-fe2e47e68801" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_07af6c2e-6e75-4555-b9e0-38531c3678b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAssetAmortization"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LeaseCostAbstract_32129260-5868-4fe0-99bc-c588e9b94233" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_07af6c2e-6e75-4555-b9e0-38531c3678b4" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_FinanceLeaseCost_14596c9a-dd1e-4a7f-88b8-4d186f9029c9" xlink:href="ppg-20201231.xsd#ppg_FinanceLeaseCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LeaseCostAbstract_32129260-5868-4fe0-99bc-c588e9b94233" xlink:to="loc_ppg_FinanceLeaseCost_14596c9a-dd1e-4a7f-88b8-4d186f9029c9" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCost_7d5648bd-56b1-426c-89f9-a17af6eb99e7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeaseCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_b6ca121f-a08e-4945-9d30-4ff5ddca99ce" xlink:to="loc_us-gaap_LeaseCost_7d5648bd-56b1-426c-89f9-a17af6eb99e7" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableLeaseCost_b62d9be1-77f3-483d-b30d-5c9b42c49113" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_VariableLeaseCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_b6ca121f-a08e-4945-9d30-4ff5ddca99ce" xlink:to="loc_us-gaap_VariableLeaseCost_b62d9be1-77f3-483d-b30d-5c9b42c49113" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermLeaseCost_3272a360-5cd6-4065-9917-2d1bab3bd02a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermLeaseCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_b6ca121f-a08e-4945-9d30-4ff5ddca99ce" xlink:to="loc_us-gaap_ShortTermLeaseCost_3272a360-5cd6-4065-9917-2d1bab3bd02a" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_21cf5bba-ae44-47c1-8d0a-3cb0570a98f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_b6ca121f-a08e-4945-9d30-4ff5ddca99ce" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_21cf5bba-ae44-47c1-8d0a-3cb0570a98f9" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_5ba50b8a-cd00-462b-8605-13bc23913d63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_21cf5bba-ae44-47c1-8d0a-3cb0570a98f9" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_5ba50b8a-cd00-462b-8605-13bc23913d63" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_5ba50b8a-cd00-462b-8605-13bc23913d63_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_5ba50b8a-cd00-462b-8605-13bc23913d63" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_5ba50b8a-cd00-462b-8605-13bc23913d63_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_860b3ca0-e45c-4b0b-8212-644b848cbf87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_5ba50b8a-cd00-462b-8605-13bc23913d63" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_860b3ca0-e45c-4b0b-8212-644b848cbf87" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfSalesMember_954214d4-e403-4a75-8179-11e87d9eab45" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CostOfSalesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_860b3ca0-e45c-4b0b-8212-644b848cbf87" xlink:to="loc_us-gaap_CostOfSalesMember_954214d4-e403-4a75-8179-11e87d9eab45" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_64986c62-ad05-48ab-9fce-6c7aa1469955" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_860b3ca0-e45c-4b0b-8212-644b848cbf87" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_64986c62-ad05-48ab-9fce-6c7aa1469955" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/LeasesAdditionalInformationDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#LeasesAdditionalInformationDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/LeasesAdditionalInformationDetails" xlink:type="extended" id="i283b3ff3b5bf4dabab1f5387f2fdf8ff_LeasesAdditionalInformationDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/LeasesScheduleofClassificationontheCondensedConsolidatedBalanceSheetDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#LeasesScheduleofClassificationontheCondensedConsolidatedBalanceSheetDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/LeasesScheduleofClassificationontheCondensedConsolidatedBalanceSheetDetails" xlink:type="extended" id="ia09a521f583d4d18aab4ed60d29e5065_LeasesScheduleofClassificationontheCondensedConsolidatedBalanceSheetDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/LeasesScheduleofCashPaidforLeaseLiabilitiesandRightofUseAssetsObtainedinExchangeforLeaseObligationsDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#LeasesScheduleofCashPaidforLeaseLiabilitiesandRightofUseAssetsObtainedinExchangeforLeaseObligationsDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/LeasesScheduleofCashPaidforLeaseLiabilitiesandRightofUseAssetsObtainedinExchangeforLeaseObligationsDetails" xlink:type="extended" id="ie09d78b5b69040afa85df33e523ef55b_LeasesScheduleofCashPaidforLeaseLiabilitiesandRightofUseAssetsObtainedinExchangeforLeaseObligationsDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/LeasesScheduleofWeightedAverageRemainingLeaseTermandWeightedAverageDiscountRateDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#LeasesScheduleofWeightedAverageRemainingLeaseTermandWeightedAverageDiscountRateDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/LeasesScheduleofWeightedAverageRemainingLeaseTermandWeightedAverageDiscountRateDetails" xlink:type="extended" id="i4d340296869646008a0914e0b2ad2da0_LeasesScheduleofWeightedAverageRemainingLeaseTermandWeightedAverageDiscountRateDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/LeasesScheduleofMaturitiesofLeaseLiabilitiesDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#LeasesScheduleofMaturitiesofLeaseLiabilitiesDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/LeasesScheduleofMaturitiesofLeaseLiabilitiesDetails" xlink:type="extended" id="i874c70d96d4848ae95e142636954d661_LeasesScheduleofMaturitiesofLeaseLiabilitiesDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/BorrowingsandLinesofCredit" xlink:type="simple" xlink:href="ppg-20201231.xsd#BorrowingsandLinesofCredit"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BorrowingsandLinesofCredit" xlink:type="extended" id="i555b32d840a74e77a5ec271fa352479e_BorrowingsandLinesofCredit"/>
<link:roleRef roleURI="http://www.ppg.com/role/BorrowingsandLinesofCreditTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#BorrowingsandLinesofCreditTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BorrowingsandLinesofCreditTables" xlink:type="extended" id="ic7d7816996be4b4689b928efbb06a7bf_BorrowingsandLinesofCreditTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/BorrowingsandLinesofCreditLongtermDebtObligationsDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#BorrowingsandLinesofCreditLongtermDebtObligationsDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BorrowingsandLinesofCreditLongtermDebtObligationsDetails" xlink:type="extended" id="ic2dc11e254764972ade8881c8bc1f7e3_BorrowingsandLinesofCreditLongtermDebtObligationsDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_aa3d8272-9950-46ad-9047-ab2465535fed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebt"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LongTermDebt_aa3d8272-9950-46ad-9047-ab2465535fed" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCredit_b12d8ea9-50de-4d2c-81a2-9d1f8c733298" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCredit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LineOfCredit_b12d8ea9-50de-4d2c-81a2-9d1f8c733298" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiability_06e9d2f7-43b3-4047-a556-b232a8c944f7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiability"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_FinanceLeaseLiability_06e9d2f7-43b3-4047-a556-b232a8c944f7" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalLeaseObligations_38545078-2c2e-46c1-8de1-917a313ec794" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CapitalLeaseObligations"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_CapitalLeaseObligations_38545078-2c2e-46c1-8de1-917a313ec794" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_14544040-824a-48b9-9163-b31cd2d68777" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligations"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_14544040-824a-48b9-9163-b31cd2d68777" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_acef6895-cfb9-430e-bc02-095059f782a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LongTermDebtCurrent_acef6895-cfb9-430e-bc02-095059f782a3" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_832bfed8-9009-4778-b474-6c9b42f6486f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_832bfed8-9009-4778-b474-6c9b42f6486f" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_27ef6825-160a-48cc-8c34-8377388c30c7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_27ef6825-160a-48cc-8c34-8377388c30c7" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAmountOfHedgedItem_549daae2-ce60-4cd5-9bf7-3c01c858e411" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAmountOfHedgedItem"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_DerivativeAmountOfHedgedItem_549daae2-ce60-4cd5-9bf7-3c01c858e411" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtPercentageBearingVariableInterestRate_a04f4ac7-8585-4dc9-9856-e37807d185d8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtPercentageBearingVariableInterestRate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LongTermDebtPercentageBearingVariableInterestRate_a04f4ac7-8585-4dc9-9856-e37807d185d8" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfDebt_d9571b49-cd39-45a1-8afc-69aa56e5e266" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfDebt"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_RepaymentsOfDebt_d9571b49-cd39-45a1-8afc-69aa56e5e266" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_792ee9d8-dd82-4194-96fb-dbbfad0622a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_792ee9d8-dd82-4194-96fb-dbbfad0622a7" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_LineOfCreditFacilityAdditionalBorrowingCapacityAvailable_2a806118-2e90-454f-9985-4641227e99ac" xlink:href="ppg-20201231.xsd#ppg_LineOfCreditFacilityAdditionalBorrowingCapacityAvailable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_LineOfCreditFacilityAdditionalBorrowingCapacityAvailable_2a806118-2e90-454f-9985-4641227e99ac" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityUnusedCapacityCommitmentFeePercentage_758c1d28-c8ae-4b1d-9a12-58eddaeb65a0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityUnusedCapacityCommitmentFeePercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_LineOfCreditFacilityUnusedCapacityCommitmentFeePercentage_758c1d28-c8ae-4b1d-9a12-58eddaeb65a0" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotionalAmountOfNonderivativeInstruments_9478a65a-583c-4e92-a64b-7bfb6403aff8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotionalAmountOfNonderivativeInstruments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_NotionalAmountOfNonderivativeInstruments_9478a65a-583c-4e92-a64b-7bfb6403aff8" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_b50fb676-06ce-4e9e-b260-8b80f41d86f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_b50fb676-06ce-4e9e-b260-8b80f41d86f2" xlink:type="arc" order="15"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_dd31099e-fc66-4a21-8766-f0def2815a19" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_dd31099e-fc66-4a21-8766-f0def2815a19" xlink:type="arc" order="16"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtRedemptionPricePercentOfPrincipalAmount_ab599019-f131-478b-a164-083f401eaa47" xlink:href="ppg-20201231.xsd#ppg_DebtRedemptionPricePercentOfPrincipalAmount"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_DebtRedemptionPricePercentOfPrincipalAmount_ab599019-f131-478b-a164-083f401eaa47" xlink:type="arc" order="17"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtInstrumentRedemptionChargeMakeWholeCashPremium_795bdd84-fea0-4ba6-a8dd-93249d0571fd" xlink:href="ppg-20201231.xsd#ppg_DebtInstrumentRedemptionChargeMakeWholeCashPremium"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_DebtInstrumentRedemptionChargeMakeWholeCashPremium_795bdd84-fea0-4ba6-a8dd-93249d0571fd" xlink:type="arc" order="18"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_f0244d8c-4f5b-4ce2-a7b4-b5902b1d8a1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_f0244d8c-4f5b-4ce2-a7b4-b5902b1d8a1a" xlink:type="arc" order="19"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_WriteOffOfDeferredDebtIssuanceCost_3dfabcfe-9551-4b90-9a93-1a626857c0e5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WriteOffOfDeferredDebtIssuanceCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_WriteOffOfDeferredDebtIssuanceCost_3dfabcfe-9551-4b90-9a93-1a626857c0e5" xlink:type="arc" order="20"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfUnsecuredDebt_1ade2ac4-8471-47a7-a062-79ea1cb0f78a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfUnsecuredDebt"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_RepaymentsOfUnsecuredDebt_1ade2ac4-8471-47a7-a062-79ea1cb0f78a" xlink:type="arc" order="21"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPaperNoncurrent_8b460875-f78b-4f4c-bc00-83237ae503d0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialPaperNoncurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_CommercialPaperNoncurrent_8b460875-f78b-4f4c-bc00-83237ae503d0" xlink:type="arc" order="22"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtInstrumentCovenantTotalIndebtednessToTotalCapitalizationRatioMaximumPercentage_ef93509b-7dbd-4ac2-91dc-b825ae3aa854" xlink:href="ppg-20201231.xsd#ppg_DebtInstrumentCovenantTotalIndebtednessToTotalCapitalizationRatioMaximumPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_DebtInstrumentCovenantTotalIndebtednessToTotalCapitalizationRatioMaximumPercentage_ef93509b-7dbd-4ac2-91dc-b825ae3aa854" xlink:type="arc" order="23"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtInstrumentCovenantAcquisitionForConsiderationMinimumThreshold_8376cbaa-1eb4-4b7d-93b8-198fb1ecd613" xlink:href="ppg-20201231.xsd#ppg_DebtInstrumentCovenantAcquisitionForConsiderationMinimumThreshold"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_DebtInstrumentCovenantAcquisitionForConsiderationMinimumThreshold_8376cbaa-1eb4-4b7d-93b8-198fb1ecd613" xlink:type="arc" order="24"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtInstrumentCovenantTotalIndebtednessToTotalCapitalizationRatioMaximumWhenAcquisitionForConsiderationThresholdIsMetPercentage_dabfa409-2a1c-44bc-9b74-269dba9759b7" xlink:href="ppg-20201231.xsd#ppg_DebtInstrumentCovenantTotalIndebtednessToTotalCapitalizationRatioMaximumWhenAcquisitionForConsiderationThresholdIsMetPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_DebtInstrumentCovenantTotalIndebtednessToTotalCapitalizationRatioMaximumWhenAcquisitionForConsiderationThresholdIsMetPercentage_dabfa409-2a1c-44bc-9b74-269dba9759b7" xlink:type="arc" order="25"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtInstrumentTotalIndebtednessToTotalCapitalizationPercentage_e3b0907d-97a4-475b-a489-349fc568b2ea" xlink:href="ppg-20201231.xsd#ppg_DebtInstrumentTotalIndebtednessToTotalCapitalizationPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_DebtInstrumentTotalIndebtednessToTotalCapitalizationPercentage_e3b0907d-97a4-475b-a489-349fc568b2ea" xlink:type="arc" order="26"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_LongTermDebtContingentPaymentofPrincipal_853f7463-ce5c-4829-a546-c60df49268a8" xlink:href="ppg-20201231.xsd#ppg_LongTermDebtContingentPaymentofPrincipal"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_ppg_LongTermDebtContingentPaymentofPrincipal_853f7463-ce5c-4829-a546-c60df49268a8" xlink:type="arc" order="27"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_b2e395ee-5cc1-4333-9fb0-01b016b7df14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_04689aeb-1786-480b-ba81-983398a1164b" xlink:to="loc_us-gaap_DebtInstrumentTable_b2e395ee-5cc1-4333-9fb0-01b016b7df14" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_30cbdbc0-fa00-40c0-9181-5a75543eccf2" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_b2e395ee-5cc1-4333-9fb0-01b016b7df14" xlink:to="loc_srt_RangeAxis_30cbdbc0-fa00-40c0-9181-5a75543eccf2" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_30cbdbc0-fa00-40c0-9181-5a75543eccf2_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_30cbdbc0-fa00-40c0-9181-5a75543eccf2" xlink:to="loc_srt_RangeMember_30cbdbc0-fa00-40c0-9181-5a75543eccf2_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_a8ea2314-e6a0-4977-a3ed-39b1607e8cd1" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_30cbdbc0-fa00-40c0-9181-5a75543eccf2" xlink:to="loc_srt_RangeMember_a8ea2314-e6a0-4977-a3ed-39b1607e8cd1" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_79acea65-efd2-4ecd-88e4-fe7b27fc6258" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_a8ea2314-e6a0-4977-a3ed-39b1607e8cd1" xlink:to="loc_srt_MinimumMember_79acea65-efd2-4ecd-88e4-fe7b27fc6258" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_ba969d2a-c56f-46e8-8c5c-61007016ee10" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_a8ea2314-e6a0-4977-a3ed-39b1607e8cd1" xlink:to="loc_srt_MaximumMember_ba969d2a-c56f-46e8-8c5c-61007016ee10" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_d78c7454-fb7f-4f58-a333-b0865303ed5f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_b2e395ee-5cc1-4333-9fb0-01b016b7df14" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_d78c7454-fb7f-4f58-a333-b0865303ed5f" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_d78c7454-fb7f-4f58-a333-b0865303ed5f_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_d78c7454-fb7f-4f58-a333-b0865303ed5f" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_d78c7454-fb7f-4f58-a333-b0865303ed5f_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_d78c7454-fb7f-4f58-a333-b0865303ed5f" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes0.00Due2019Member_42dc5177-5c6a-4657-88e1-79b991494747" xlink:href="ppg-20201231.xsd#ppg_Notes0.00Due2019Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes0.00Due2019Member_42dc5177-5c6a-4657-88e1-79b991494747" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes2.3PercentDue2019Member_a801957f-909d-435b-874c-af767307469e" xlink:href="ppg-20201231.xsd#ppg_Notes2.3PercentDue2019Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes2.3PercentDue2019Member_a801957f-909d-435b-874c-af767307469e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes3600PercentDue2020Member_1aa680c7-58c3-4ab8-82ac-97a88ea5d6d9" xlink:href="ppg-20201231.xsd#ppg_Notes3600PercentDue2020Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes3600PercentDue2020Member_1aa680c7-58c3-4ab8-82ac-97a88ea5d6d9" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NonCallableDebentures9PercentDue2021Member_6ae14059-df82-46f7-81c2-c4e3a9e7d33b" xlink:href="ppg-20201231.xsd#ppg_NonCallableDebentures9PercentDue2021Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_NonCallableDebentures9PercentDue2021Member_6ae14059-df82-46f7-81c2-c4e3a9e7d33b" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes0.875PercentDue2022Member_b7000dfb-4355-4f64-917b-4109b7709a06" xlink:href="ppg-20201231.xsd#ppg_Notes0.875PercentDue2022Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes0.875PercentDue2022Member_b7000dfb-4355-4f64-917b-4109b7709a06" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A3.2Notesdue2023Member_4468090c-4704-4477-9d74-9b2f236cd612" xlink:href="ppg-20201231.xsd#ppg_A3.2Notesdue2023Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_A3.2Notesdue2023Member_4468090c-4704-4477-9d74-9b2f236cd612" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A2.4Notesdue2024Member_f0523016-931b-413c-b3a0-e7ba35267f99" xlink:href="ppg-20201231.xsd#ppg_A2.4Notesdue2024Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_A2.4Notesdue2024Member_f0523016-931b-413c-b3a0-e7ba35267f99" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes0.875Due2025Member_b7c7e672-e033-40c8-856a-e3699218974c" xlink:href="ppg-20201231.xsd#ppg_Notes0.875Due2025Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes0.875Due2025Member_b7c7e672-e033-40c8-856a-e3699218974c" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes1.4PercentDue2027Member_89856e11-a808-4956-b84d-17b6dd7ffccc" xlink:href="ppg-20201231.xsd#ppg_Notes1.4PercentDue2027Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes1.4PercentDue2027Member_89856e11-a808-4956-b84d-17b6dd7ffccc" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A3.75Notesdue2028Member_04345dc6-6de4-4ca1-a34d-3ab5b314c50d" xlink:href="ppg-20201231.xsd#ppg_A3.75Notesdue2028Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_A3.75Notesdue2028Member_04345dc6-6de4-4ca1-a34d-3ab5b314c50d" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A2.8Notesdue2029Member_4da167c4-1658-4fd5-888f-f750a03c93cb" xlink:href="ppg-20201231.xsd#ppg_A2.8Notesdue2029Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_A2.8Notesdue2029Member_4da167c4-1658-4fd5-888f-f750a03c93cb" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A255NotesDue2030Member_bfe67128-de04-41d8-b691-8f22a484da7b" xlink:href="ppg-20201231.xsd#ppg_A255NotesDue2030Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_A255NotesDue2030Member_bfe67128-de04-41d8-b691-8f22a484da7b" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Note2.5PercentDue2029Member_0f4bec56-f420-4621-a49b-ed3e20717b2c" xlink:href="ppg-20201231.xsd#ppg_Note2.5PercentDue2029Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Note2.5PercentDue2029Member_0f4bec56-f420-4621-a49b-ed3e20717b2c" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes770PercentDue2038Member_10530c04-6842-435d-b671-8e5c257e1846" xlink:href="ppg-20201231.xsd#ppg_Notes770PercentDue2038Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes770PercentDue2038Member_10530c04-6842-435d-b671-8e5c257e1846" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Notes5500PercentDue2040Member_2c9b84ba-9cb4-4efc-9be7-b2882ca7fca5" xlink:href="ppg-20201231.xsd#ppg_Notes5500PercentDue2040Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Notes5500PercentDue2040Member_2c9b84ba-9cb4-4efc-9be7-b2882ca7fca5" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Note3.0PercentDue2044Member_921154d2-db14-4d35-bbde-9e0114351e15" xlink:href="ppg-20201231.xsd#ppg_Note3.0PercentDue2044Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_Note3.0PercentDue2044Member_921154d2-db14-4d35-bbde-9e0114351e15" xlink:type="arc" order="15"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPaperMember_75a11ebc-7a72-4b4e-8c37-682ce19b8661" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommercialPaperMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_us-gaap_CommercialPaperMember_75a11ebc-7a72-4b4e-8c37-682ce19b8661" xlink:type="arc" order="16"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_OtherNonUSDebtWeightedAverage70PercentMember_b3674579-e297-4bf9-ab48-77555349b346" xlink:href="ppg-20201231.xsd#ppg_OtherNonUSDebtWeightedAverage70PercentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_OtherNonUSDebtWeightedAverage70PercentMember_b3674579-e297-4bf9-ab48-77555349b346" xlink:type="arc" order="17"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ImpactOfDerivativesOnDebtMember_115ca70e-aa6c-4563-94dd-f99a9ee4c707" xlink:href="ppg-20201231.xsd#ppg_ImpactOfDerivativesOnDebtMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_4d397821-0ded-4bd8-9a4d-4ff9a2964d31" xlink:to="loc_ppg_ImpactOfDerivativesOnDebtMember_115ca70e-aa6c-4563-94dd-f99a9ee4c707" xlink:type="arc" order="18"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/BorrowingsandLinesofCreditLongtermDebtMaturitiesDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#BorrowingsandLinesofCreditLongtermDebtMaturitiesDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BorrowingsandLinesofCreditLongtermDebtMaturitiesDetails" xlink:type="extended" id="i83d1bec1bfde41e39a6ca726c20c0944_BorrowingsandLinesofCreditLongtermDebtMaturitiesDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/BorrowingsandLinesofCreditShorttermDebtOutstandingDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#BorrowingsandLinesofCreditShorttermDebtOutstandingDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BorrowingsandLinesofCreditShorttermDebtOutstandingDetail" xlink:type="extended" id="icd0c82301e0a4dbe9e279409ec30384c_BorrowingsandLinesofCreditShorttermDebtOutstandingDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermDebtLineItems_d613712e-1d3e-466c-b175-3503e048e645" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermDebtLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermBorrowings_cf53a147-aacd-4d9f-a418-7901dbef7965" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermBorrowings"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShortTermDebtLineItems_d613712e-1d3e-466c-b175-3503e048e645" xlink:to="loc_us-gaap_ShortTermBorrowings_cf53a147-aacd-4d9f-a418-7901dbef7965" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermDebtWeightedAverageInterestRate_6aa71a4f-b73b-4c46-b8da-358d522c981d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermDebtWeightedAverageInterestRate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShortTermDebtLineItems_d613712e-1d3e-466c-b175-3503e048e645" xlink:to="loc_us-gaap_ShortTermDebtWeightedAverageInterestRate_6aa71a4f-b73b-4c46-b8da-358d522c981d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTerm_e4a5ef44-2299-49b5-b7c5-2646f6698693" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTerm"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShortTermDebtLineItems_d613712e-1d3e-466c-b175-3503e048e645" xlink:to="loc_us-gaap_DebtInstrumentTerm_e4a5ef44-2299-49b5-b7c5-2646f6698693" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShortTermDebtTable_caaf23cf-76cb-4cf8-937a-ac9f517293c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShortTermDebtTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShortTermDebtLineItems_d613712e-1d3e-466c-b175-3503e048e645" xlink:to="loc_us-gaap_ScheduleOfShortTermDebtTable_caaf23cf-76cb-4cf8-937a-ac9f517293c5" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermDebtTypeAxis_20ea8fdf-e42a-4765-aa19-a2305ec2011b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermDebtTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShortTermDebtTable_caaf23cf-76cb-4cf8-937a-ac9f517293c5" xlink:to="loc_us-gaap_ShortTermDebtTypeAxis_20ea8fdf-e42a-4765-aa19-a2305ec2011b" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermDebtTypeDomain_20ea8fdf-e42a-4765-aa19-a2305ec2011b_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermDebtTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ShortTermDebtTypeAxis_20ea8fdf-e42a-4765-aa19-a2305ec2011b" xlink:to="loc_us-gaap_ShortTermDebtTypeDomain_20ea8fdf-e42a-4765-aa19-a2305ec2011b_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermDebtTypeDomain_ae1b94fc-529a-43b4-8ed4-7a2ab4bee959" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermDebtTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ShortTermDebtTypeAxis_20ea8fdf-e42a-4765-aa19-a2305ec2011b" xlink:to="loc_us-gaap_ShortTermDebtTypeDomain_ae1b94fc-529a-43b4-8ed4-7a2ab4bee959" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_A15Billion364DayTermLoanMember_42d8e026-52ae-4613-9dbd-8a7250acc578" xlink:href="ppg-20201231.xsd#ppg_A15Billion364DayTermLoanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShortTermDebtTypeDomain_ae1b94fc-529a-43b4-8ed4-7a2ab4bee959" xlink:to="loc_ppg_A15Billion364DayTermLoanMember_42d8e026-52ae-4613-9dbd-8a7250acc578" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/BorrowingsandLinesofCreditAdditionalInformationDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#BorrowingsandLinesofCreditAdditionalInformationDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/BorrowingsandLinesofCreditAdditionalInformationDetails" xlink:type="extended" id="if23ce6ea210e48238f0d2ef36eab7a38_BorrowingsandLinesofCreditAdditionalInformationDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentPeriodicPayment_dfc64cde-a71a-42fa-b6fb-402e0e2e8cca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentPeriodicPayment"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_DebtInstrumentPeriodicPayment_dfc64cde-a71a-42fa-b6fb-402e0e2e8cca" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_940c8664-abda-41f5-b182-4ae17274dc37" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_940c8664-abda-41f5-b182-4ae17274dc37" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_LongTermDebtContingentPaymentofPrincipal_7ce99aa9-f89b-498d-8079-ceffb88f487f" xlink:href="ppg-20201231.xsd#ppg_LongTermDebtContingentPaymentofPrincipal"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_ppg_LongTermDebtContingentPaymentofPrincipal_7ce99aa9-f89b-498d-8079-ceffb88f487f" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityCurrentBorrowingCapacity_a6705583-2f2f-46c1-b4e3-05181dbbc8d0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCreditFacilityCurrentBorrowingCapacity"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_LineOfCreditFacilityCurrentBorrowingCapacity_a6705583-2f2f-46c1-b4e3-05181dbbc8d0" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCredit_fab602a4-8f05-43bf-9f7f-3f3687c1fa3f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LineOfCredit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_LineOfCredit_fab602a4-8f05-43bf-9f7f-3f3687c1fa3f" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_LettersOfCreditSuretyBondsAndOtherArrangements_81680b82-b697-45e0-a5e1-97988bb495c3" xlink:href="ppg-20201231.xsd#ppg_LettersOfCreditSuretyBondsAndOtherArrangements"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_ppg_LettersOfCreditSuretyBondsAndOtherArrangements_81680b82-b697-45e0-a5e1-97988bb495c3" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuarantyAssets_d571e275-227d-41d6-b5b5-f89578089e8c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuarantyAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_GuarantyAssets_d571e275-227d-41d6-b5b5-f89578089e8c" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteeObligationsCurrentCarryingValue_3b6ff8e9-2f35-46db-a0a5-0c37bdab7a36" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteeObligationsCurrentCarryingValue"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_GuaranteeObligationsCurrentCarryingValue_3b6ff8e9-2f35-46db-a0a5-0c37bdab7a36" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteesFairValueDisclosure_2ec43bc3-2000-44fd-ba15-558c08b4f865" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteesFairValueDisclosure"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_GuaranteesFairValueDisclosure_2ec43bc3-2000-44fd-ba15-558c08b4f865" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromLinesOfCredit_5fb9af20-fc41-4f28-99dc-9f0da6a18fc5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromLinesOfCredit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_ProceedsFromLinesOfCredit_5fb9af20-fc41-4f28-99dc-9f0da6a18fc5" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLinesOfCredit_282fb169-bb44-48d9-91fe-21700b204680" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfLinesOfCredit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_RepaymentsOfLinesOfCredit_282fb169-bb44-48d9-91fe-21700b204680" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTerm_7ce7a48d-1004-4aad-acee-c887fb2d1246" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTerm"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_DebtInstrumentTerm_7ce7a48d-1004-4aad-acee-c887fb2d1246" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_158dbb83-6bc2-4bff-989e-0de6f26589df" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebt"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_LongTermDebt_158dbb83-6bc2-4bff-989e-0de6f26589df" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_7053d7d7-8622-4ec8-becd-acfbf0d8f67a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ef9715cc-6021-4834-ab1f-960a40c23bb4" xlink:to="loc_us-gaap_DebtInstrumentTable_7053d7d7-8622-4ec8-becd-acfbf0d8f67a" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_0d5d5924-91f4-4074-9730-d381f1cb418f" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementGeographicalAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_7053d7d7-8622-4ec8-becd-acfbf0d8f67a" xlink:to="loc_srt_StatementGeographicalAxis_0d5d5924-91f4-4074-9730-d381f1cb418f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_0d5d5924-91f4-4074-9730-d381f1cb418f_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementGeographicalAxis_0d5d5924-91f4-4074-9730-d381f1cb418f" xlink:to="loc_srt_SegmentGeographicalDomain_0d5d5924-91f4-4074-9730-d381f1cb418f_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_d7e27262-2560-4062-91b0-f1ed6adce776" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementGeographicalAxis_0d5d5924-91f4-4074-9730-d381f1cb418f" xlink:to="loc_srt_SegmentGeographicalDomain_d7e27262-2560-4062-91b0-f1ed6adce776" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_InternationalOperationsMember_d1fa8262-12f2-43c8-8829-aafd94bdf2b2" xlink:href="ppg-20201231.xsd#ppg_InternationalOperationsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_d7e27262-2560-4062-91b0-f1ed6adce776" xlink:to="loc_ppg_InternationalOperationsMember_d1fa8262-12f2-43c8-8829-aafd94bdf2b2" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_d5255261-46b4-4d57-bf2a-3cb4c8fd6879" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_7053d7d7-8622-4ec8-becd-acfbf0d8f67a" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_d5255261-46b4-4d57-bf2a-3cb4c8fd6879" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_d5255261-46b4-4d57-bf2a-3cb4c8fd6879_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_d5255261-46b4-4d57-bf2a-3cb4c8fd6879" xlink:to="loc_us-gaap_LossContingencyNatureDomain_d5255261-46b4-4d57-bf2a-3cb4c8fd6879_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_9163c60e-9b5b-480d-ac6c-3dad4e3739a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_d5255261-46b4-4d57-bf2a-3cb4c8fd6879" xlink:to="loc_us-gaap_LossContingencyNatureDomain_9163c60e-9b5b-480d-ac6c-3dad4e3739a9" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteeOfIndebtednessOfOthersMember_fe488d56-e29f-49fd-afb4-4f105453b6a4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteeOfIndebtednessOfOthersMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyNatureDomain_9163c60e-9b5b-480d-ac6c-3dad4e3739a9" xlink:to="loc_us-gaap_GuaranteeOfIndebtednessOfOthersMember_fe488d56-e29f-49fd-afb4-4f105453b6a4" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_964d2f8f-b4bd-41a7-b867-cdd331fa6e36" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_7053d7d7-8622-4ec8-becd-acfbf0d8f67a" xlink:to="loc_srt_RangeAxis_964d2f8f-b4bd-41a7-b867-cdd331fa6e36" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_964d2f8f-b4bd-41a7-b867-cdd331fa6e36_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_964d2f8f-b4bd-41a7-b867-cdd331fa6e36" xlink:to="loc_srt_RangeMember_964d2f8f-b4bd-41a7-b867-cdd331fa6e36_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_289caa29-77c4-488c-b7ae-39666de0af5c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_964d2f8f-b4bd-41a7-b867-cdd331fa6e36" xlink:to="loc_srt_RangeMember_289caa29-77c4-488c-b7ae-39666de0af5c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_2eaae391-a40d-46e4-843e-f09a8f8de5c5" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_289caa29-77c4-488c-b7ae-39666de0af5c" xlink:to="loc_srt_MinimumMember_2eaae391-a40d-46e4-843e-f09a8f8de5c5" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_bfa932d4-b822-4b7a-9469-513412f197dd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_7053d7d7-8622-4ec8-becd-acfbf0d8f67a" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_bfa932d4-b822-4b7a-9469-513412f197dd" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_bfa932d4-b822-4b7a-9469-513412f197dd_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_bfa932d4-b822-4b7a-9469-513412f197dd" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_bfa932d4-b822-4b7a-9469-513412f197dd_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_7269b1ab-c053-44ec-b3ff-042a0d124dda" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_bfa932d4-b822-4b7a-9469-513412f197dd" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_7269b1ab-c053-44ec-b3ff-042a0d124dda" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NonCallableDebentures9PercentDue2021Member_a2d45828-e3cd-4dde-9c8b-7e2cd9bc0188" xlink:href="ppg-20201231.xsd#ppg_NonCallableDebentures9PercentDue2021Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_7269b1ab-c053-44ec-b3ff-042a0d124dda" xlink:to="loc_ppg_NonCallableDebentures9PercentDue2021Member_a2d45828-e3cd-4dde-9c8b-7e2cd9bc0188" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember_f8a72c7b-47a7-4003-8eb4-725c966a7607" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnsecuredDebtMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_7269b1ab-c053-44ec-b3ff-042a0d124dda" xlink:to="loc_us-gaap_UnsecuredDebtMember_f8a72c7b-47a7-4003-8eb4-725c966a7607" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_468d5249-8c88-4eef-a252-c419b13f4af1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_7053d7d7-8622-4ec8-becd-acfbf0d8f67a" xlink:to="loc_us-gaap_CreditFacilityAxis_468d5249-8c88-4eef-a252-c419b13f4af1" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_468d5249-8c88-4eef-a252-c419b13f4af1_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CreditFacilityAxis_468d5249-8c88-4eef-a252-c419b13f4af1" xlink:to="loc_us-gaap_CreditFacilityDomain_468d5249-8c88-4eef-a252-c419b13f4af1_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_66e19b3b-36b2-4e31-bfdb-a56e4c627486" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CreditFacilityDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CreditFacilityAxis_468d5249-8c88-4eef-a252-c419b13f4af1" xlink:to="loc_us-gaap_CreditFacilityDomain_66e19b3b-36b2-4e31-bfdb-a56e4c627486" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_821dde91-a853-4c6c-ba94-bd0e0ac1cb07" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevolvingCreditFacilityMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_66e19b3b-36b2-4e31-bfdb-a56e4c627486" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_821dde91-a853-4c6c-ba94-bd0e0ac1cb07" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurements" xlink:type="simple" xlink:href="ppg-20201231.xsd#FinancialInstrumentsHedgingActivitiesandFairValueMeasurements"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurements" xlink:type="extended" id="ibadd5b45a7784fee91b2fd732c7aef6d_FinancialInstrumentsHedgingActivitiesandFairValueMeasurements"/>
<link:roleRef roleURI="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsTables" xlink:type="extended" id="i189ffc45adab473d96802227b65405a2_FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAdditionalInformationDetail" xlink:type="extended" id="ie50b85bd95674bd3a9036b9a82edd3cc_FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAdditionalInformationDetail">
<link:loc xlink:type="locator" xlink:label="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:href="ppg-20201231.xsd#ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiability_f32b4fc1-9dd0-4b6e-b5dd-43e7dd779c9a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiability"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_FinanceLeaseLiability_f32b4fc1-9dd0-4b6e-b5dd-43e7dd779c9a" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1bae3f97-6634-4f07-9a69-3122cea738ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1bae3f97-6634-4f07-9a69-3122cea738ca" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_c39306f4-0198-4fd4-8f09-409261b4af62" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignCurrencyContractAssetFairValueDisclosure"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_c39306f4-0198-4fd4-8f09-409261b4af62" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_f63fc07f-7b88-4d4f-87e5-fa2d6e8ad1d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeNotionalAmount"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_DerivativeNotionalAmount_f63fc07f-7b88-4d4f-87e5-fa2d6e8ad1d3" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateDerivativesAtFairValueNet_6fa0fbc9-f717-41b1-9110-ce348544c738" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestRateDerivativesAtFairValueNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_InterestRateDerivativesAtFairValueNet_6fa0fbc9-f717-41b1-9110-ce348544c738" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetInvestmentHedgeDerivativesAtFairValueNet_b5b2c248-b7d6-4eb5-8c6f-74e6f7019836" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetInvestmentHedgeDerivativesAtFairValueNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_NetInvestmentHedgeDerivativesAtFairValueNet_b5b2c248-b7d6-4eb5-8c6f-74e6f7019836" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotionalAmountOfNonderivativeInstruments_fd7ab7d3-d465-4f55-879c-e5a3a5426d1b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotionalAmountOfNonderivativeInstruments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_NotionalAmountOfNonderivativeInstruments_fd7ab7d3-d465-4f55-879c-e5a3a5426d1b" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_FairValueofDebtInstrumentDesignatedasaHedgeofNetInvestmentinForeignOperations_ead6c87a-fe40-4521-8f46-0b0288dc6ace" xlink:href="ppg-20201231.xsd#ppg_FairValueofDebtInstrumentDesignatedasaHedgeofNetInvestmentinForeignOperations"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_ppg_FairValueofDebtInstrumentDesignatedasaHedgeofNetInvestmentinForeignOperations_ead6c87a-fe40-4521-8f46-0b0288dc6ace" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_19930cac-4850-4d2f-b9c6-3d523d1ac8b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_19930cac-4850-4d2f-b9c6-3d523d1ac8b4" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable_bed3b923-6452-4eb0-a200-1ad3b2cae8a3" xlink:href="ppg-20201231.xsd#ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_14ededa4-94ff-42f2-ad82-8b4aa4fa4621" xlink:to="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable_bed3b923-6452-4eb0-a200-1ad3b2cae8a3" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_785ba7c1-408c-428c-a082-21dcaa8745ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable_bed3b923-6452-4eb0-a200-1ad3b2cae8a3" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_785ba7c1-408c-428c-a082-21dcaa8745ca" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_785ba7c1-408c-428c-a082-21dcaa8745ca_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_785ba7c1-408c-428c-a082-21dcaa8745ca" xlink:to="loc_us-gaap_EquityComponentDomain_785ba7c1-408c-428c-a082-21dcaa8745ca_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_61010ec9-342e-46d5-b949-c9a7c11e96f5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_785ba7c1-408c-428c-a082-21dcaa8745ca" xlink:to="loc_us-gaap_EquityComponentDomain_61010ec9-342e-46d5-b949-c9a7c11e96f5" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossCashFlowHedgeIncludingNoncontrollingInterestMember_85a93ae1-e634-4c84-b3e7-f6257be9d105" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedGainLossCashFlowHedgeIncludingNoncontrollingInterestMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_61010ec9-342e-46d5-b949-c9a7c11e96f5" xlink:to="loc_us-gaap_AccumulatedGainLossCashFlowHedgeIncludingNoncontrollingInterestMember_85a93ae1-e634-4c84-b3e7-f6257be9d105" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_19aae064-b114-4e76-af9d-88234d443995" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable_bed3b923-6452-4eb0-a200-1ad3b2cae8a3" xlink:to="loc_us-gaap_HedgingDesignationAxis_19aae064-b114-4e76-af9d-88234d443995" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_19aae064-b114-4e76-af9d-88234d443995_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_19aae064-b114-4e76-af9d-88234d443995" xlink:to="loc_us-gaap_HedgingDesignationDomain_19aae064-b114-4e76-af9d-88234d443995_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_c5694540-43ef-443f-b7c9-fa8fabab1e0d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_19aae064-b114-4e76-af9d-88234d443995" xlink:to="loc_us-gaap_HedgingDesignationDomain_c5694540-43ef-443f-b7c9-fa8fabab1e0d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_ae2b5f4f-0d3d-4068-ac15-35372e51c19f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_c5694540-43ef-443f-b7c9-fa8fabab1e0d" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_ae2b5f4f-0d3d-4068-ac15-35372e51c19f" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_f831ba07-266d-4488-973d-974239a3e1db" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable_bed3b923-6452-4eb0-a200-1ad3b2cae8a3" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_f831ba07-266d-4488-973d-974239a3e1db" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_f831ba07-266d-4488-973d-974239a3e1db_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_f831ba07-266d-4488-973d-974239a3e1db" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_f831ba07-266d-4488-973d-974239a3e1db_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_82b05d85-ee26-4d64-80f5-cd6e2c1f7b2c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_f831ba07-266d-4488-973d-974239a3e1db" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_82b05d85-ee26-4d64-80f5-cd6e2c1f7b2c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_d259332a-8200-478b-bed0-5bec9462537b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_82b05d85-ee26-4d64-80f5-cd6e2c1f7b2c" xlink:to="loc_us-gaap_ForeignExchangeContractMember_d259332a-8200-478b-bed0-5bec9462537b" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_2b30ef89-6750-41b9-8bc2-3b1525c2eb9b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestRateSwapMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_82b05d85-ee26-4d64-80f5-cd6e2c1f7b2c" xlink:to="loc_us-gaap_InterestRateSwapMember_2b30ef89-6750-41b9-8bc2-3b1525c2eb9b" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CrossCurrencyInterestRateContractMember_0ff29981-2adf-4ff3-b890-ac3f6d8cac63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CrossCurrencyInterestRateContractMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_82b05d85-ee26-4d64-80f5-cd6e2c1f7b2c" xlink:to="loc_us-gaap_CrossCurrencyInterestRateContractMember_0ff29981-2adf-4ff3-b890-ac3f6d8cac63" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrencySwapMember_88d0ee4c-5e8b-47f2-b0a2-f8ff1d77132d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CurrencySwapMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_82b05d85-ee26-4d64-80f5-cd6e2c1f7b2c" xlink:to="loc_us-gaap_CurrencySwapMember_88d0ee4c-5e8b-47f2-b0a2-f8ff1d77132d" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_222e03ce-ac03-4c36-b822-91b7678715b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable_bed3b923-6452-4eb0-a200-1ad3b2cae8a3" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_222e03ce-ac03-4c36-b822-91b7678715b4" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_222e03ce-ac03-4c36-b822-91b7678715b4_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_222e03ce-ac03-4c36-b822-91b7678715b4" xlink:to="loc_us-gaap_HedgingRelationshipDomain_222e03ce-ac03-4c36-b822-91b7678715b4_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_ff22ce64-eaa9-4409-9454-d0d67d9b5bbf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_222e03ce-ac03-4c36-b822-91b7678715b4" xlink:to="loc_us-gaap_HedgingRelationshipDomain_ff22ce64-eaa9-4409-9454-d0d67d9b5bbf" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_d1c9ce94-9527-4e69-b7f6-19a3e061dbd6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_ff22ce64-eaa9-4409-9454-d0d67d9b5bbf" xlink:to="loc_us-gaap_CashFlowHedgingMember_d1c9ce94-9527-4e69-b7f6-19a3e061dbd6" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetInvestmentHedgingMember_fef0d41c-b8fd-445e-bd17-03bda6b8aaf2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetInvestmentHedgingMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_ff22ce64-eaa9-4409-9454-d0d67d9b5bbf" xlink:to="loc_us-gaap_NetInvestmentHedgingMember_fef0d41c-b8fd-445e-bd17-03bda6b8aaf2" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DerivativesByDerivativeInstrumentContractAxis_bb90a894-4898-4d0a-9b41-5f123fa6d9bf" xlink:href="ppg-20201231.xsd#ppg_DerivativesByDerivativeInstrumentContractAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_DerivativeInstrumentsAndHedgingActivitiesDisclosureTable_bed3b923-6452-4eb0-a200-1ad3b2cae8a3" xlink:to="loc_ppg_DerivativesByDerivativeInstrumentContractAxis_bb90a894-4898-4d0a-9b41-5f123fa6d9bf" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DerivativesByDerivativeInstrumentContractDomain_bb90a894-4898-4d0a-9b41-5f123fa6d9bf_default" xlink:href="ppg-20201231.xsd#ppg_DerivativesByDerivativeInstrumentContractDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_ppg_DerivativesByDerivativeInstrumentContractAxis_bb90a894-4898-4d0a-9b41-5f123fa6d9bf" xlink:to="loc_ppg_DerivativesByDerivativeInstrumentContractDomain_bb90a894-4898-4d0a-9b41-5f123fa6d9bf_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DerivativesByDerivativeInstrumentContractDomain_b9a41e62-e4bb-4053-9d77-1d01a3f637da" xlink:href="ppg-20201231.xsd#ppg_DerivativesByDerivativeInstrumentContractDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ppg_DerivativesByDerivativeInstrumentContractAxis_bb90a894-4898-4d0a-9b41-5f123fa6d9bf" xlink:to="loc_ppg_DerivativesByDerivativeInstrumentContractDomain_b9a41e62-e4bb-4053-9d77-1d01a3f637da" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_SettlementDate15March2018Member_6f61165b-d933-4712-a415-538862759892" xlink:href="ppg-20201231.xsd#ppg_SettlementDate15March2018Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_DerivativesByDerivativeInstrumentContractDomain_b9a41e62-e4bb-4053-9d77-1d01a3f637da" xlink:to="loc_ppg_SettlementDate15March2018Member_6f61165b-d933-4712-a415-538862759892" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueCashFlowandNetInvestmentHedgesDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueCashFlowandNetInvestmentHedgesDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueCashFlowandNetInvestmentHedgesDetail" xlink:type="extended" id="i906957fb34384c3db9d9e8d1b00cf753_FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueCashFlowandNetInvestmentHedgesDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativesFairValueLineItems_040c1845-5d96-454e-90cf-af6245c89752" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativesFairValueLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotionalAmountOfNonderivativeInstruments_f766d80e-3078-453a-b191-7d2791d1ef25" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotionalAmountOfNonderivativeInstruments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_040c1845-5d96-454e-90cf-af6245c89752" xlink:to="loc_us-gaap_NotionalAmountOfNonderivativeInstruments_f766d80e-3078-453a-b191-7d2791d1ef25" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax_19064a7a-0773-4f38-876c-382fc86061b6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_040c1845-5d96-454e-90cf-af6245c89752" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax_19064a7a-0773-4f38-876c-382fc86061b6" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeGainLossOnDerivativeNet_ac5a71a9-c127-45d2-b17a-aa3ba515faf6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeGainLossOnDerivativeNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_040c1845-5d96-454e-90cf-af6245c89752" xlink:to="loc_us-gaap_DerivativeGainLossOnDerivativeNet_ac5a71a9-c127-45d2-b17a-aa3ba515faf6" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_fbc10171-6aa3-4d8a-9b40-2cae183ff1e4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_040c1845-5d96-454e-90cf-af6245c89752" xlink:to="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_fbc10171-6aa3-4d8a-9b40-2cae183ff1e4" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_cf816d57-9eea-4c31-bf2a-44d939d56356" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_fbc10171-6aa3-4d8a-9b40-2cae183ff1e4" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_cf816d57-9eea-4c31-bf2a-44d939d56356" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_cf816d57-9eea-4c31-bf2a-44d939d56356_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_cf816d57-9eea-4c31-bf2a-44d939d56356" xlink:to="loc_us-gaap_HedgingRelationshipDomain_cf816d57-9eea-4c31-bf2a-44d939d56356_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_7b82ab16-8787-412b-b5a6-c79bc7e50990" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingRelationshipDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_cf816d57-9eea-4c31-bf2a-44d939d56356" xlink:to="loc_us-gaap_HedgingRelationshipDomain_7b82ab16-8787-412b-b5a6-c79bc7e50990" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueHedgingMember_093c1f9a-ef31-42ca-9a0a-2eb0469f849d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueHedgingMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7b82ab16-8787-412b-b5a6-c79bc7e50990" xlink:to="loc_us-gaap_FairValueHedgingMember_093c1f9a-ef31-42ca-9a0a-2eb0469f849d" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_27bf7205-3d06-423b-b40b-f2a6747458cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashFlowHedgingMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7b82ab16-8787-412b-b5a6-c79bc7e50990" xlink:to="loc_us-gaap_CashFlowHedgingMember_27bf7205-3d06-423b-b40b-f2a6747458cf" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetInvestmentHedgingMember_7f146925-938d-4f98-bd3b-80f4a3d030d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetInvestmentHedgingMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7b82ab16-8787-412b-b5a6-c79bc7e50990" xlink:to="loc_us-gaap_NetInvestmentHedgingMember_7f146925-938d-4f98-bd3b-80f4a3d030d3" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_EconomicHedgingMember_023eda2d-f7a4-4403-bbfa-d4c6dea0562f" xlink:href="ppg-20201231.xsd#ppg_EconomicHedgingMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7b82ab16-8787-412b-b5a6-c79bc7e50990" xlink:to="loc_ppg_EconomicHedgingMember_023eda2d-f7a4-4403-bbfa-d4c6dea0562f" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_9a63297e-b79d-411e-86fd-3552a311fc8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_fbc10171-6aa3-4d8a-9b40-2cae183ff1e4" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_9a63297e-b79d-411e-86fd-3552a311fc8b" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_9a63297e-b79d-411e-86fd-3552a311fc8b_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_9a63297e-b79d-411e-86fd-3552a311fc8b" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_9a63297e-b79d-411e-86fd-3552a311fc8b_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_856983d3-1545-4e98-9e73-5f05e738392e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_9a63297e-b79d-411e-86fd-3552a311fc8b" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_856983d3-1545-4e98-9e73-5f05e738392e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_4c8486df-c239-47c9-9d48-6592f514c75f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_856983d3-1545-4e98-9e73-5f05e738392e" xlink:to="loc_us-gaap_ForeignExchangeContractMember_4c8486df-c239-47c9-9d48-6592f514c75f" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrencySwapMember_6282632b-bafe-4c59-9f88-1794daf90fe7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CurrencySwapMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_856983d3-1545-4e98-9e73-5f05e738392e" xlink:to="loc_us-gaap_CurrencySwapMember_6282632b-bafe-4c59-9f88-1794daf90fe7" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_OtherForeignCurrencyDenominatedDebtMember_286b56c2-f1e0-4bb7-91fa-e6fb2ea63c3c" xlink:href="ppg-20201231.xsd#ppg_OtherForeignCurrencyDenominatedDebtMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_856983d3-1545-4e98-9e73-5f05e738392e" xlink:to="loc_ppg_OtherForeignCurrencyDenominatedDebtMember_286b56c2-f1e0-4bb7-91fa-e6fb2ea63c3c" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_f2da626b-c67e-4b97-b2d3-47d90d808ba7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_fbc10171-6aa3-4d8a-9b40-2cae183ff1e4" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_f2da626b-c67e-4b97-b2d3-47d90d808ba7" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_f2da626b-c67e-4b97-b2d3-47d90d808ba7_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_f2da626b-c67e-4b97-b2d3-47d90d808ba7" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_f2da626b-c67e-4b97-b2d3-47d90d808ba7_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_ae622d59-1bdc-4276-9334-1c913fe24657" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_f2da626b-c67e-4b97-b2d3-47d90d808ba7" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_ae622d59-1bdc-4276-9334-1c913fe24657" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseMember_9b0e3b02-1251-4c3b-af12-4c0646759096" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestExpenseMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ae622d59-1bdc-4276-9334-1c913fe24657" xlink:to="loc_us-gaap_InterestExpenseMember_9b0e3b02-1251-4c3b-af12-4c0646759096" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherExpenseMember_cc30d549-0c9f-4e08-a2df-c79e0d8185e7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherExpenseMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ae622d59-1bdc-4276-9334-1c913fe24657" xlink:to="loc_us-gaap_OtherExpenseMember_cc30d549-0c9f-4e08-a2df-c79e0d8185e7" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAssetsandLiabilitiesReportedatFairValueonaRecurringBasisDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAssetsandLiabilitiesReportedatFairValueonaRecurringBasisDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAssetsandLiabilitiesReportedatFairValueonaRecurringBasisDetail" xlink:type="extended" id="i3e37efb86ce148b6bcbf9dc58acae44d_FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsAssetsandLiabilitiesReportedatFairValueonaRecurringBasisDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_17b8295f-2e73-484f-bbe2-fa076a270ab0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_79e34cf9-ff81-4e80-8ec2-a04fe5bbba41" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_17b8295f-2e73-484f-bbe2-fa076a270ab0" xlink:to="loc_us-gaap_DerivativeAssets_79e34cf9-ff81-4e80-8ec2-a04fe5bbba41" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities_5807635b-19ba-4a22-a331-66ad43de4670" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_17b8295f-2e73-484f-bbe2-fa076a270ab0" xlink:to="loc_us-gaap_DerivativeLiabilities_5807635b-19ba-4a22-a331-66ad43de4670" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_96ee2d95-47d5-4f90-a787-37c60f770e16" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_17b8295f-2e73-484f-bbe2-fa076a270ab0" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_96ee2d95-47d5-4f90-a787-37c60f770e16" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_e4a0b8a8-3dd5-4cf2-b131-a582b842c8e7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_96ee2d95-47d5-4f90-a787-37c60f770e16" xlink:to="loc_us-gaap_HedgingDesignationAxis_e4a0b8a8-3dd5-4cf2-b131-a582b842c8e7" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_e4a0b8a8-3dd5-4cf2-b131-a582b842c8e7_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_e4a0b8a8-3dd5-4cf2-b131-a582b842c8e7" xlink:to="loc_us-gaap_HedgingDesignationDomain_e4a0b8a8-3dd5-4cf2-b131-a582b842c8e7_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_28048660-8e52-4804-bb32-b492495b67a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_HedgingDesignationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_e4a0b8a8-3dd5-4cf2-b131-a582b842c8e7" xlink:to="loc_us-gaap_HedgingDesignationDomain_28048660-8e52-4804-bb32-b492495b67a5" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_cf70da78-576b-45fa-85fe-c0ebbdb9cc69" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NondesignatedMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_28048660-8e52-4804-bb32-b492495b67a5" xlink:to="loc_us-gaap_NondesignatedMember_cf70da78-576b-45fa-85fe-c0ebbdb9cc69" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7acf57c6-9788-459f-9017-2c1e1d808ad7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_96ee2d95-47d5-4f90-a787-37c60f770e16" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7acf57c6-9788-459f-9017-2c1e1d808ad7" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_7acf57c6-9788-459f-9017-2c1e1d808ad7_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7acf57c6-9788-459f-9017-2c1e1d808ad7" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_7acf57c6-9788-459f-9017-2c1e1d808ad7_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0ef30308-72ab-433b-926f-1050f8f54ec8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7acf57c6-9788-459f-9017-2c1e1d808ad7" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0ef30308-72ab-433b-926f-1050f8f54ec8" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_3c34477c-0b70-45b4-bb25-fe42c97b4f49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0ef30308-72ab-433b-926f-1050f8f54ec8" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_3c34477c-0b70-45b4-bb25-fe42c97b4f49" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_e11291ea-0bdf-419e-9a4a-45b583fcf720" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0ef30308-72ab-433b-926f-1050f8f54ec8" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_e11291ea-0bdf-419e-9a4a-45b583fcf720" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_f0e24140-6dca-49c9-aed9-96bf871ba5a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_96ee2d95-47d5-4f90-a787-37c60f770e16" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_f0e24140-6dca-49c9-aed9-96bf871ba5a3" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_f0e24140-6dca-49c9-aed9-96bf871ba5a3_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_f0e24140-6dca-49c9-aed9-96bf871ba5a3" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_f0e24140-6dca-49c9-aed9-96bf871ba5a3_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_f0e24140-6dca-49c9-aed9-96bf871ba5a3" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermInvestmentsMember_4d1c5d94-e139-4218-abe0-3765020ed39b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShortTermInvestmentsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:to="loc_us-gaap_ShortTermInvestmentsMember_4d1c5d94-e139-4218-abe0-3765020ed39b" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsMember_c4649010-fe88-4b93-be7b-e52634387959" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCurrentAssetsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:to="loc_us-gaap_OtherCurrentAssetsMember_c4649010-fe88-4b93-be7b-e52634387959" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsMember_c2e8b460-a89a-46ed-848c-059b3049429e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:to="loc_us-gaap_OtherAssetsMember_c2e8b460-a89a-46ed-848c-059b3049429e" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsMember_d3275ef2-769c-4b22-9f0e-3e94ffc70b9c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InvestmentsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:to="loc_us-gaap_InvestmentsMember_d3275ef2-769c-4b22-9f0e-3e94ffc70b9c" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesMember_ca870012-b5c5-4046-8b6a-d7d44f4831fc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesMember_ca870012-b5c5-4046-8b6a-d7d44f4831fc" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesMember_cf4dc8ed-a055-40bb-8d1a-68188f8e14ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherLiabilitiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_db2b1ef0-9f15-4348-a92c-1ff1c0db1c66" xlink:to="loc_us-gaap_OtherLiabilitiesMember_cf4dc8ed-a055-40bb-8d1a-68188f8e14ce" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_bbfc9d13-8b93-4bde-b0e7-b7b38ad28eac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_96ee2d95-47d5-4f90-a787-37c60f770e16" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_bbfc9d13-8b93-4bde-b0e7-b7b38ad28eac" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_bbfc9d13-8b93-4bde-b0e7-b7b38ad28eac_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_bbfc9d13-8b93-4bde-b0e7-b7b38ad28eac" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_bbfc9d13-8b93-4bde-b0e7-b7b38ad28eac_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_aff33d92-5bfe-483f-a308-ea8423a4c4e6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeContractTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_bbfc9d13-8b93-4bde-b0e7-b7b38ad28eac" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_aff33d92-5bfe-483f-a308-ea8423a4c4e6" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesMember_ef891e83-8132-4c45-a068-55a9d2b6e776" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_aff33d92-5bfe-483f-a308-ea8423a4c4e6" xlink:to="loc_us-gaap_EquitySecuritiesMember_ef891e83-8132-4c45-a068-55a9d2b6e776" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeContractMember_ad71477b-0e6e-4eaa-9d09-4adb51fd81ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignExchangeContractMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_aff33d92-5bfe-483f-a308-ea8423a4c4e6" xlink:to="loc_us-gaap_ForeignExchangeContractMember_ad71477b-0e6e-4eaa-9d09-4adb51fd81ed" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CrossCurrencyInterestRateContractMember_9230941d-b8e0-472b-a202-3af0daa0c7df" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CrossCurrencyInterestRateContractMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_aff33d92-5bfe-483f-a308-ea8423a4c4e6" xlink:to="loc_us-gaap_CrossCurrencyInterestRateContractMember_9230941d-b8e0-472b-a202-3af0daa0c7df" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_27544bc3-c3bc-4ed9-b208-5b1bf6b98d8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestRateSwapMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_aff33d92-5bfe-483f-a308-ea8423a4c4e6" xlink:to="loc_us-gaap_InterestRateSwapMember_27544bc3-c3bc-4ed9-b208-5b1bf6b98d8b" xlink:type="arc" order="3"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueAdditionalInformationDetail" xlink:type="extended" id="i10dbfb96ee68460a8e95d43ca2d033b3_FinancialInstrumentsHedgingActivitiesandFairValueMeasurementsFairValueAdditionalInformationDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/EarningsPerCommonShare" xlink:type="simple" xlink:href="ppg-20201231.xsd#EarningsPerCommonShare"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EarningsPerCommonShare" xlink:type="extended" id="ifc4ce9d581f64e6a9cdf5a8f3ee404ee_EarningsPerCommonShare"/>
<link:roleRef roleURI="http://www.ppg.com/role/EarningsPerCommonShareTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#EarningsPerCommonShareTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EarningsPerCommonShareTables" xlink:type="extended" id="idd34348fc9d4480e9fc3bbef217f4e03_EarningsPerCommonShareTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/EarningsPerCommonShareAdditionalDetailDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EarningsPerCommonShareAdditionalDetailDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EarningsPerCommonShareAdditionalDetailDetail" xlink:type="extended" id="i05b906582a5346c89ffd45834911f169_EarningsPerCommonShareAdditionalDetailDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/IncomeTaxes" xlink:type="simple" xlink:href="ppg-20201231.xsd#IncomeTaxes"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/IncomeTaxes" xlink:type="extended" id="iabae4c6f1551467cac740eb48fa10b80_IncomeTaxes"/>
<link:roleRef roleURI="http://www.ppg.com/role/IncomeTaxesTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#IncomeTaxesTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/IncomeTaxesTables" xlink:type="extended" id="i7bbc298a21034ecd86477896aa7d2477_IncomeTaxesTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/IncomeTaxesAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#IncomeTaxesAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/IncomeTaxesAdditionalInformationDetail" xlink:type="extended" id="i52c5802391ae47cbb756e80b03dc088c_IncomeTaxesAdditionalInformationDetail">
<link:loc xlink:type="locator" xlink:label="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:href="ppg-20201231.xsd#ppg_IncomeTaxesLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Benefitfromreversalofexistingdeferredtaxliabilityonrepatriatedforeignearnings_baff5e13-a5fa-4040-aa96-aba2e52ad5d6" xlink:href="ppg-20201231.xsd#ppg_Benefitfromreversalofexistingdeferredtaxliabilityonrepatriatedforeignearnings"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_Benefitfromreversalofexistingdeferredtaxliabilityonrepatriatedforeignearnings_baff5e13-a5fa-4040-aa96-aba2e52ad5d6" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_TaxCutsandJobsActAccountingCompleteIncomeTaxExpenseBenefitForeignDerivedIntangibleIncome_1b5865ed-38d3-4ad6-a579-54e8e8966ed8" xlink:href="ppg-20201231.xsd#ppg_TaxCutsandJobsActAccountingCompleteIncomeTaxExpenseBenefitForeignDerivedIntangibleIncome"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_TaxCutsandJobsActAccountingCompleteIncomeTaxExpenseBenefitForeignDerivedIntangibleIncome_1b5865ed-38d3-4ad6-a579-54e8e8966ed8" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_TaxCutsAndJobsActOf2017AccountingCompleteIncomeTaxExpenseBenefitGlobalIntangibleLowTaxIncome_a5c3d536-a4ad-4134-8faa-26e920e37d35" xlink:href="ppg-20201231.xsd#ppg_TaxCutsAndJobsActOf2017AccountingCompleteIncomeTaxExpenseBenefitGlobalIntangibleLowTaxIncome"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_TaxCutsAndJobsActOf2017AccountingCompleteIncomeTaxExpenseBenefitGlobalIntangibleLowTaxIncome_a5c3d536-a4ad-4134-8faa-26e920e37d35" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_244d828f-9e21-4e87-ba45-e9b0656bddbb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_244d828f-9e21-4e87-ba45-e9b0656bddbb" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_89ec43e8-5c35-4b81-bf60-e9a26d95852c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_89ec43e8-5c35-4b81-bf60-e9a26d95852c" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NoncashPensionSettlementChargebeforetax_c0664db7-5b78-4a5e-9abe-ab29e8eaf6df" xlink:href="ppg-20201231.xsd#ppg_NoncashPensionSettlementChargebeforetax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_NoncashPensionSettlementChargebeforetax_c0664db7-5b78-4a5e-9abe-ab29e8eaf6df" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IncomeLossFromContinuingOperationsBeforeIncomeTaxes_226acf9f-3123-41ea-bdbc-c524b5617945" xlink:href="ppg-20201231.xsd#ppg_IncomeLossFromContinuingOperationsBeforeIncomeTaxes"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_IncomeLossFromContinuingOperationsBeforeIncomeTaxes_226acf9f-3123-41ea-bdbc-c524b5617945" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwards_6f611a48-634d-4851-a938-5571d5f030ea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwards"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_OperatingLossCarryforwards_6f611a48-634d-4851-a938-5571d5f030ea" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsOther_84a1aa5d-ab63-4612-8489-b2364a135f49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsOther"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsOther_84a1aa5d-ab63-4612-8489-b2364a135f49" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate_d1bf425d-0bfc-4f6c-8098-3c3ea55bd5c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate_d1bf425d-0bfc-4f6c-8098-3c3ea55bd5c9" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued_cd8f9c35-b30d-4c07-b7fa-c1b864d687c6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued_cd8f9c35-b30d-4c07-b7fa-c1b864d687c6" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_f6928be7-c04f-441c-aff3-9de5d513612c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_f6928be7-c04f-441c-aff3-9de5d513612c" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UndistributedEarningsOfForeignSubsidiaries_61acd757-1a16-4d58-97b3-d1256bb96cde" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UndistributedEarningsOfForeignSubsidiaries"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_us-gaap_UndistributedEarningsOfForeignSubsidiaries_61acd757-1a16-4d58-97b3-d1256bb96cde" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NumberOfTaxableJurisdictions_25452907-3e06-43f4-a2eb-d0d9226243ed" xlink:href="ppg-20201231.xsd#ppg_NumberOfTaxableJurisdictions"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_NumberOfTaxableJurisdictions_25452907-3e06-43f4-a2eb-d0d9226243ed" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NettaxchargeforTaxCutsJobsAct_0b43fb3a-3ba9-4edf-9c57-0e3165d79564" xlink:href="ppg-20201231.xsd#ppg_NettaxchargeforTaxCutsJobsAct"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_NettaxchargeforTaxCutsJobsAct_0b43fb3a-3ba9-4edf-9c57-0e3165d79564" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Taxchargeonunrepatriatedforeignearnings_64e2cae7-380c-4bb0-9d45-87008ae99213" xlink:href="ppg-20201231.xsd#ppg_Taxchargeonunrepatriatedforeignearnings"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_Taxchargeonunrepatriatedforeignearnings_64e2cae7-380c-4bb0-9d45-87008ae99213" xlink:type="arc" order="15"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NumberOfPpgSubsidiaries_61932e31-8a0d-4f95-88d7-019c8235c881" xlink:href="ppg-20201231.xsd#ppg_NumberOfPpgSubsidiaries"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_NumberOfPpgSubsidiaries_61932e31-8a0d-4f95-88d7-019c8235c881" xlink:type="arc" order="16"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IncomeTaxPotentialUSTaxCostForRepatriationOfForeignEarnings_3f05b776-6e27-4d3b-b171-647da8ebafd0" xlink:href="ppg-20201231.xsd#ppg_IncomeTaxPotentialUSTaxCostForRepatriationOfForeignEarnings"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_IncomeTaxPotentialUSTaxCostForRepatriationOfForeignEarnings_3f05b776-6e27-4d3b-b171-647da8ebafd0" xlink:type="arc" order="17"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IncomeTaxesTable_7cdc83e6-1e1c-4f0c-90a4-b26cb08bbaf6" xlink:href="ppg-20201231.xsd#ppg_IncomeTaxesTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_ppg_IncomeTaxesLineItems_253e3b57-72c7-47e7-a93b-5caca0ecb023" xlink:to="loc_ppg_IncomeTaxesTable_7cdc83e6-1e1c-4f0c-90a4-b26cb08bbaf6" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_8808fd24-915f-4b33-a656-b6835949910e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_IncomeTaxesTable_7cdc83e6-1e1c-4f0c-90a4-b26cb08bbaf6" xlink:to="loc_srt_RangeAxis_8808fd24-915f-4b33-a656-b6835949910e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_8808fd24-915f-4b33-a656-b6835949910e_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_8808fd24-915f-4b33-a656-b6835949910e" xlink:to="loc_srt_RangeMember_8808fd24-915f-4b33-a656-b6835949910e_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_9911f6ac-eab0-473d-81e4-26aefb9bf380" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_8808fd24-915f-4b33-a656-b6835949910e" xlink:to="loc_srt_RangeMember_9911f6ac-eab0-473d-81e4-26aefb9bf380" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_110e0398-19a2-41dc-a246-509130d54527" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_9911f6ac-eab0-473d-81e4-26aefb9bf380" xlink:to="loc_srt_MinimumMember_110e0398-19a2-41dc-a246-509130d54527" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_9ca775de-8dd1-4710-8c8c-7ebe0476c4bd" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_9911f6ac-eab0-473d-81e4-26aefb9bf380" xlink:to="loc_srt_MaximumMember_9ca775de-8dd1-4710-8c8c-7ebe0476c4bd" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_70684108-edb5-4b16-8a07-23975545fa5f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_IncomeTaxesTable_7cdc83e6-1e1c-4f0c-90a4-b26cb08bbaf6" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_70684108-edb5-4b16-8a07-23975545fa5f" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_70684108-edb5-4b16-8a07-23975545fa5f_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_70684108-edb5-4b16-8a07-23975545fa5f" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_70684108-edb5-4b16-8a07-23975545fa5f_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_a4d50635-70e1-403b-aab8-8b8d1da2ae6b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_70684108-edb5-4b16-8a07-23975545fa5f" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_a4d50635-70e1-403b-aab8-8b8d1da2ae6b" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticCountryMember_c5af8860-4bbc-421a-ac6f-501284021754" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticCountryMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_a4d50635-70e1-403b-aab8-8b8d1da2ae6b" xlink:to="loc_us-gaap_DomesticCountryMember_c5af8860-4bbc-421a-ac6f-501284021754" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NonUnitedStatesMember_f149dad8-5179-43d4-88f6-2260b3dce52e" xlink:href="ppg-20201231.xsd#ppg_NonUnitedStatesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_a4d50635-70e1-403b-aab8-8b8d1da2ae6b" xlink:to="loc_ppg_NonUnitedStatesMember_f149dad8-5179-43d4-88f6-2260b3dce52e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NetOperatingLossIndefiniteLifeMember_a387ebed-9cd7-4016-981a-f252683f6036" xlink:href="ppg-20201231.xsd#ppg_NetOperatingLossIndefiniteLifeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_a4d50635-70e1-403b-aab8-8b8d1da2ae6b" xlink:to="loc_ppg_NetOperatingLossIndefiniteLifeMember_a387ebed-9cd7-4016-981a-f252683f6036" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NetOperatingLossExpiringWithin20YearsMember_1745ba2c-f154-452b-a8d5-4e063749f436" xlink:href="ppg-20201231.xsd#ppg_NetOperatingLossExpiringWithin20YearsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_a4d50635-70e1-403b-aab8-8b8d1da2ae6b" xlink:to="loc_ppg_NetOperatingLossExpiringWithin20YearsMember_1745ba2c-f154-452b-a8d5-4e063749f436" xlink:type="arc" order="3"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/IncomeTaxesComponentsofIncomeTaxExpenseDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#IncomeTaxesComponentsofIncomeTaxExpenseDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/IncomeTaxesComponentsofIncomeTaxExpenseDetail" xlink:type="extended" id="i26fae7e2d5e84a7e8fa18ffd137c00fa_IncomeTaxesComponentsofIncomeTaxExpenseDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/IncomeTaxesReconciliationofStatutoryUSCorporateFederalIncomeTaxRatetoEffectiveIncomeTaxRateDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#IncomeTaxesReconciliationofStatutoryUSCorporateFederalIncomeTaxRatetoEffectiveIncomeTaxRateDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/IncomeTaxesReconciliationofStatutoryUSCorporateFederalIncomeTaxRatetoEffectiveIncomeTaxRateDetail" xlink:type="extended" id="i1dc05dda16c742eab24c1c97708d45dd_IncomeTaxesReconciliationofStatutoryUSCorporateFederalIncomeTaxRatetoEffectiveIncomeTaxRateDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/IncomeTaxesNetDeferredIncomeTaxAssetsandLiabilitiesDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#IncomeTaxesNetDeferredIncomeTaxAssetsandLiabilitiesDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/IncomeTaxesNetDeferredIncomeTaxAssetsandLiabilitiesDetail" xlink:type="extended" id="iabebe1563e024155ba9705c5b99bd49f_IncomeTaxesNetDeferredIncomeTaxAssetsandLiabilitiesDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesBalance_3a0e05c9-5b99-4bc4-92bc-c6136324de5e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesBalance"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesBalance_3a0e05c9-5b99-4bc4-92bc-c6136324de5e" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwardsExpirationDate_7f3ffc8a-b2ea-4c34-b1e5-fe99004f0b09" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwardsExpirationDate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_OperatingLossCarryforwardsExpirationDate_7f3ffc8a-b2ea-4c34-b1e5-fe99004f0b09" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxCreditCarryforwardExpirationDate_8e6aa27a-ca3a-43c0-b12c-be66b0960789" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxCreditCarryforwardExpirationDate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_TaxCreditCarryforwardExpirationDate_8e6aa27a-ca3a-43c0-b12c-be66b0960789" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits_bd655e97-940c-4859-82ed-373fad5d3db9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits_bd655e97-940c-4859-82ed-373fad5d3db9" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies_8917376f-2a4f-4bc6-b5e8-b85479565c27" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies_8917376f-2a4f-4bc6-b5e8-b85479565c27" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_f0ce4e3f-c708-45f8-bb67-61ca1df30eb1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_f0ce4e3f-c708-45f8-bb67-61ca1df30eb1" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsInventory_26750697-8205-40aa-b153-596d4ebb026b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsInventory"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsInventory_26750697-8205-40aa-b153-596d4ebb026b" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsOther_e2e01636-e7f4-4ed0-a60b-5f1d98c1d6a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsOther"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsOther_e2e01636-e7f4-4ed0-a60b-5f1d98c1d6a3" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_e8671a78-6008-41c3-88e1-55929fadf308" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsOther"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_e8671a78-6008-41c3-88e1-55929fadf308" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_0ecfebb1-344e-4d13-9c72-0568d8128b52" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_0ecfebb1-344e-4d13-9c72-0568d8128b52" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_0a0a35e6-be86-481a-954f-c8efd06f754b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_0a0a35e6-be86-481a-954f-c8efd06f754b" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_cf04b593-7f0c-482a-871d-c2899e392066" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_cf04b593-7f0c-482a-871d-c2899e392066" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssets_a6af470c-72a6-4157-9b0d-f5de197a154f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssets_a6af470c-72a6-4157-9b0d-f5de197a154f" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DeferredTaxLiabilitiesCompensationAndBenefits_64a3ac14-e980-4675-9d84-a105a882e50f" xlink:href="ppg-20201231.xsd#ppg_DeferredTaxLiabilitiesCompensationAndBenefits"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_ppg_DeferredTaxLiabilitiesCompensationAndBenefits_64a3ac14-e980-4675-9d84-a105a882e50f" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesLeasingArrangements_726a3920-008e-4102-8e94-dce567c21e20" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxLiabilitiesLeasingArrangements"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesLeasingArrangements_726a3920-008e-4102-8e94-dce567c21e20" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesOther_3a60abcb-8c0a-494f-b472-4ec32606e316" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxLiabilitiesOther"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesOther_3a60abcb-8c0a-494f-b472-4ec32606e316" xlink:type="arc" order="15"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_497b8ab7-9edb-40c6-9d1c-654b9764ca5a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_497b8ab7-9edb-40c6-9d1c-654b9764ca5a" xlink:type="arc" order="16"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilities_ea6a4ef0-db98-429e-83d1-e6612f637c3f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_DeferredTaxLiabilities_ea6a4ef0-db98-429e-83d1-e6612f637c3f" xlink:type="arc" order="17"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExaminationTable_14647e86-b6ab-4a17-90b4-b736ec3974b9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExaminationTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_87507cd1-b362-467c-9415-2a544a09c65b" xlink:to="loc_us-gaap_IncomeTaxExaminationTable_14647e86-b6ab-4a17-90b4-b736ec3974b9" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_9fad80da-5fe6-41a2-94b8-06d7f46cef21" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeTaxExaminationTable_14647e86-b6ab-4a17-90b4-b736ec3974b9" xlink:to="loc_srt_RangeAxis_9fad80da-5fe6-41a2-94b8-06d7f46cef21" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_9fad80da-5fe6-41a2-94b8-06d7f46cef21_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_9fad80da-5fe6-41a2-94b8-06d7f46cef21" xlink:to="loc_srt_RangeMember_9fad80da-5fe6-41a2-94b8-06d7f46cef21_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_f2c6e417-85e3-4da1-af96-3419f5b6ce91" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_9fad80da-5fe6-41a2-94b8-06d7f46cef21" xlink:to="loc_srt_RangeMember_f2c6e417-85e3-4da1-af96-3419f5b6ce91" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_8627663b-ef1f-4b2a-9040-9512cbc0f036" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_f2c6e417-85e3-4da1-af96-3419f5b6ce91" xlink:to="loc_srt_MinimumMember_8627663b-ef1f-4b2a-9040-9512cbc0f036" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_7a330698-2573-4fc6-bae6-e01f9660502c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_f2c6e417-85e3-4da1-af96-3419f5b6ce91" xlink:to="loc_srt_MaximumMember_7a330698-2573-4fc6-bae6-e01f9660502c" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/IncomeTaxesUnrecognizedTaxBenefitsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#IncomeTaxesUnrecognizedTaxBenefitsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/IncomeTaxesUnrecognizedTaxBenefitsDetail" xlink:type="extended" id="idc94c24e66334514b7c2fa4efbd018e5_IncomeTaxesUnrecognizedTaxBenefitsDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlans" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlans"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlans" xlink:type="extended" id="ib201127247a04d7c8c11f7fd3bd9a06c_EmployeeBenefitPlans"/>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansTables" xlink:type="extended" id="if7d2f35c423547e1a94346e1e48ebb7b_EmployeeBenefitPlansTables">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfBenefitObligationsInExcessOfFairValueOfPlanAssetsTableTextBlock_ddb3fb9f-4349-4743-81ad-04312f23ca81" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfBenefitObligationsInExcessOfFairValueOfPlanAssetsTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfBenefitObligationsInExcessOfFairValueOfPlanAssetsTableTextBlock_ddb3fb9f-4349-4743-81ad-04312f23ca81" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfNetPeriodicBenefitCostNotYetRecognizedTableTextBlock_49707c96-753c-4da5-ae46-4fc268454e28" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfNetPeriodicBenefitCostNotYetRecognizedTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfNetPeriodicBenefitCostNotYetRecognizedTableTextBlock_49707c96-753c-4da5-ae46-4fc268454e28" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock_31205ff5-0b47-4eb2-9fd9-88cd04bde595" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock_31205ff5-0b47-4eb2-9fd9-88cd04bde595" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfNetBenefitCostsTableTextBlock_89ed0041-2096-4b4a-a1de-b715c565641e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfNetBenefitCostsTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfNetBenefitCostsTableTextBlock_89ed0041-2096-4b4a-a1de-b715c565641e" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAssumptionsUsedTableTextBlock_ae39b32a-9c88-490a-8d3d-7229c1a57414" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAssumptionsUsedTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfAssumptionsUsedTableTextBlock_ae39b32a-9c88-490a-8d3d-7229c1a57414" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTextBlock_4cbe4ca7-bcc9-4034-b2bf-8022d523b4f6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTextBlock_4cbe4ca7-bcc9-4034-b2bf-8022d523b4f6" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfExpectedBenefitPaymentsTableTextBlock_9903fc8a-f186-4b88-931c-4ec4d1130354" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfExpectedBenefitPaymentsTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfExpectedBenefitPaymentsTableTextBlock_9903fc8a-f186-4b88-931c-4ec4d1130354" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAllocationOfPlanAssetsTableTextBlock_b3f2b513-c5a3-476b-ad55-9c8c18fd15ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAllocationOfPlanAssetsTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfAllocationOfPlanAssetsTableTextBlock_b3f2b513-c5a3-476b-ad55-9c8c18fd15ce" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfChangesInFairValueOfPlanAssetsTableTextBlock_e9b6381f-9303-4d4f-b84a-33f0c4c76103" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfChangesInFairValueOfPlanAssetsTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfChangesInFairValueOfPlanAssetsTableTextBlock_e9b6381f-9303-4d4f-b84a-33f0c4c76103" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEffectOfSignificantUnobservableInputsChangesInPlanAssetsTableTextBlock_21ecbef9-a18d-4c8e-a0e6-fdb130aa415b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfEffectOfSignificantUnobservableInputsChangesInPlanAssetsTableTextBlock"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_ScheduleOfEffectOfSignificantUnobservableInputsChangesInPlanAssetsTableTextBlock_21ecbef9-a18d-4c8e-a0e6-fdb130aa415b" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_cce5afdd-4016-4047-91f2-73a465f82272" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_49929d18-077b-4f27-9db2-7d47981389ce" xlink:to="loc_us-gaap_StatementTable_cce5afdd-4016-4047-91f2-73a465f82272" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_52eba661-15af-46f4-951b-6da0105c8956" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_cce5afdd-4016-4047-91f2-73a465f82272" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_52eba661-15af-46f4-951b-6da0105c8956" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_52eba661-15af-46f4-951b-6da0105c8956_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_52eba661-15af-46f4-951b-6da0105c8956" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_52eba661-15af-46f4-951b-6da0105c8956_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_3ea757c5-f43e-4c6c-a9ab-ac0d639b764a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_52eba661-15af-46f4-951b-6da0105c8956" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_3ea757c5-f43e-4c6c-a9ab-ac0d639b764a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_BenefitObligationsMember_dda52cfe-5e25-49c5-9ae9-56d4648e8743" xlink:href="ppg-20201231.xsd#ppg_BenefitObligationsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_3ea757c5-f43e-4c6c-a9ab-ac0d639b764a" xlink:to="loc_ppg_BenefitObligationsMember_dda52cfe-5e25-49c5-9ae9-56d4648e8743" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_BenefitCostsMember_c42bbc71-6dec-4083-89fb-631338814366" xlink:href="ppg-20201231.xsd#ppg_BenefitCostsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_3ea757c5-f43e-4c6c-a9ab-ac0d639b764a" xlink:to="loc_ppg_BenefitCostsMember_c42bbc71-6dec-4083-89fb-631338814366" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansAdditionalInformationDetail" xlink:type="extended" id="i80543badd70a482fbcbc9579c2ec000d_EmployeeBenefitPlansAdditionalInformationDetail">
<link:loc xlink:type="locator" xlink:label="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:href="ppg-20201231.xsd#ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAmendments_4f1f42f3-b741-474a-864b-b3935689e45c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAmendments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAmendments_4f1f42f3-b741-474a-864b-b3935689e45c" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_622705ae-aabe-4566-9204-067f442dad38" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanContributionsByEmployer"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_622705ae-aabe-4566-9204-067f442dad38" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid_df20f535-539c-4e30-8eb9-36660a01993c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid_df20f535-539c-4e30-8eb9-36660a01993c" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NoncashPensionSettlementChargebeforetax_d9157671-350d-404e-a73c-92d20449393e" xlink:href="ppg-20201231.xsd#ppg_NoncashPensionSettlementChargebeforetax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_ppg_NoncashPensionSettlementChargebeforetax_d9157671-350d-404e-a73c-92d20449393e" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedBenefitObligation_31110a3f-566e-4c77-952d-56df57feb6e8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedBenefitObligation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedBenefitObligation_31110a3f-566e-4c77-952d-56df57feb6e8" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax_8c74cc8e-2933-45ba-9071-f326dcc8cf49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax_8c74cc8e-2933-45ba-9071-f326dcc8cf49" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets_2154b1c5-0d2d-486b-b193-419069f9a7a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets_2154b1c5-0d2d-486b-b193-419069f9a7a1" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ImpactonNetPeriodicPensionExpenseNextTwelveMonths_af8f31f1-87ff-4388-a929-393f70a0c77b" xlink:href="ppg-20201231.xsd#ppg_ImpactonNetPeriodicPensionExpenseNextTwelveMonths"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_ppg_ImpactonNetPeriodicPensionExpenseNextTwelveMonths_af8f31f1-87ff-4388-a929-393f70a0c77b" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanHealthCareCostTrendRateAssumedNextFiscalYear_9119701d-5882-44fb-9ae4-1f79b6347d8a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanHealthCareCostTrendRateAssumedNextFiscalYear"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanHealthCareCostTrendRateAssumedNextFiscalYear_9119701d-5882-44fb-9ae4-1f79b6347d8a" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanUltimateHealthCareCostTrendRate1_d0f7dd90-a369-4e99-a8c8-a002bb595372" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanUltimateHealthCareCostTrendRate1"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanUltimateHealthCareCostTrendRate1_d0f7dd90-a369-4e99-a8c8-a002bb595372" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanEstimatedFutureEmployerContributionsinNextFiscalYearLowendofRange_c845aeb3-9027-4681-908e-bb4efea6731c" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanEstimatedFutureEmployerContributionsinNextFiscalYearLowendofRange"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_ppg_DefinedBenefitPlanEstimatedFutureEmployerContributionsinNextFiscalYearLowendofRange_c845aeb3-9027-4681-908e-bb4efea6731c" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPensionPlanWithProjectedBenefitObligationInExcessOfPlanAssetsProjectedBenefitObligation_f1c37c48-f11e-43ae-8af7-e923c5283657" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPensionPlanWithProjectedBenefitObligationInExcessOfPlanAssetsProjectedBenefitObligation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanPensionPlanWithProjectedBenefitObligationInExcessOfPlanAssetsProjectedBenefitObligation_f1c37c48-f11e-43ae-8af7-e923c5283657" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPensionPlanWithProjectedBenefitObligationInExcessOfPlanAssetsPlanAssets_f4a5264d-1654-4abf-a3b6-bf5f47a0a26e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPensionPlanWithProjectedBenefitObligationInExcessOfPlanAssetsPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanPensionPlanWithProjectedBenefitObligationInExcessOfPlanAssetsPlanAssets_f4a5264d-1654-4abf-a3b6-bf5f47a0a26e" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPensionPlansWithAccumulatedBenefitObligationsInExcessOfPlanAssetsAggregateAccumulatedBenefitObligation_fc853df1-0a98-4f78-be24-4f0b62aeae88" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPensionPlansWithAccumulatedBenefitObligationsInExcessOfPlanAssetsAggregateAccumulatedBenefitObligation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanPensionPlansWithAccumulatedBenefitObligationsInExcessOfPlanAssetsAggregateAccumulatedBenefitObligation_fc853df1-0a98-4f78-be24-4f0b62aeae88" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPensionPlansWithAccumulatedBenefitObligationsInExcessOfPlanAssetsAggregateFairValueOfPlanAssets_4fb3d928-40a2-4a49-8ca4-5d662ab65b36" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPensionPlansWithAccumulatedBenefitObligationsInExcessOfPlanAssetsAggregateFairValueOfPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanPensionPlansWithAccumulatedBenefitObligationsInExcessOfPlanAssetsAggregateFairValueOfPlanAssets_4fb3d928-40a2-4a49-8ca4-5d662ab65b36" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsNextTwelveMonths_f02097bb-5df8-4816-bf17-fdf6f785918b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsNextTwelveMonths"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsNextTwelveMonths_f02097bb-5df8-4816-bf17-fdf6f785918b" xlink:type="arc" order="15"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearTwo_da568c1b-3f8c-4ba4-9cc1-0838cd9e6349" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearTwo"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearTwo_da568c1b-3f8c-4ba4-9cc1-0838cd9e6349" xlink:type="arc" order="16"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearThree_b64e28ee-f603-408d-bcdb-8bbfa0b713d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearThree"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearThree_b64e28ee-f603-408d-bcdb-8bbfa0b713d7" xlink:type="arc" order="17"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFour_2b620db3-6f49-4eaf-ad04-3d1387cb4be6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFour"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFour_2b620db3-6f49-4eaf-ad04-3d1387cb4be6" xlink:type="arc" order="18"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFive_59fe5d1b-a42d-46cc-9aac-723107794b07" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFive"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsYearFive_59fe5d1b-a42d-46cc-9aac-723107794b07" xlink:type="arc" order="19"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsFiveFiscalYearsThereafter_1ce7a5ca-d7a2-4bb0-b679-1232ef92d3dc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsFiveFiscalYearsThereafter"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedFutureBenefitPaymentsFiveFiscalYearsThereafter_1ce7a5ca-d7a2-4bb0-b679-1232ef92d3dc" xlink:type="arc" order="20"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanPercentageOfPensionPlanAssets_d91dc5ae-705f-44f7-83d9-a89d6135a8c4" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanPercentageOfPensionPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_ppg_DefinedBenefitPlanPercentageOfPensionPlanAssets_d91dc5ae-705f-44f7-83d9-a89d6135a8c4" xlink:type="arc" order="21"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanEffectofPlanAmendmentonAmortizationPeriod_db879058-6400-4a48-8db1-4c6e10299d56" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanEffectofPlanAmendmentonAmortizationPeriod"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_ppg_DefinedBenefitPlanEffectofPlanAmendmentonAmortizationPeriod_db879058-6400-4a48-8db1-4c6e10299d56" xlink:type="arc" order="22"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureTable_ddfc9d73-4896-4a3c-b512-953666493c8c" xlink:href="ppg-20201231.xsd#ppg_PensionAndOtherPostretirementBenefitsDisclosureTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureLineItems_688c8300-940e-41d4-bb8c-26a205f4ec62" xlink:to="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureTable_ddfc9d73-4896-4a3c-b512-953666493c8c" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationAxis_8adf0f68-958c-4e28-853c-538fb57c8c76" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureTable_ddfc9d73-4896-4a3c-b512-953666493c8c" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationAxis_8adf0f68-958c-4e28-853c-538fb57c8c76" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_8adf0f68-958c-4e28-853c-538fb57c8c76_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_8adf0f68-958c-4e28-853c-538fb57c8c76" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_8adf0f68-958c-4e28-853c-538fb57c8c76_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_ed2f21f1-1316-4d58-a227-e2d3b8116d8d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_8adf0f68-958c-4e28-853c-538fb57c8c76" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_ed2f21f1-1316-4d58-a227-e2d3b8116d8d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticPlanMember_fa9d3534-a759-4494-a214-ac6e99a10c10" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_ed2f21f1-1316-4d58-a227-e2d3b8116d8d" xlink:to="loc_us-gaap_DomesticPlanMember_fa9d3534-a759-4494-a214-ac6e99a10c10" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_country_US_4f1828d1-7d73-4a42-a4b0-fe59c8f282fd" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_US"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DomesticPlanMember_fa9d3534-a759-4494-a214-ac6e99a10c10" xlink:to="loc_country_US_4f1828d1-7d73-4a42-a4b0-fe59c8f282fd" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignPlanMember_dc9a669e-34d5-4483-bbc4-be708dac5416" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_ed2f21f1-1316-4d58-a227-e2d3b8116d8d" xlink:to="loc_us-gaap_ForeignPlanMember_dc9a669e-34d5-4483-bbc4-be708dac5416" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_UnitedStatesCanadaNetherlandsAndUnitedKingdomMember_c75071cd-d4e0-4526-97a3-824cb381134e" xlink:href="ppg-20201231.xsd#ppg_UnitedStatesCanadaNetherlandsAndUnitedKingdomMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_ed2f21f1-1316-4d58-a227-e2d3b8116d8d" xlink:to="loc_ppg_UnitedStatesCanadaNetherlandsAndUnitedKingdomMember_c75071cd-d4e0-4526-97a3-824cb381134e" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanNameAxis_2bc19ab8-7963-424e-9d39-df70a354930c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanNameAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureTable_ddfc9d73-4896-4a3c-b512-953666493c8c" xlink:to="loc_us-gaap_RetirementPlanNameAxis_2bc19ab8-7963-424e-9d39-df70a354930c" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanNameDomain_2bc19ab8-7963-424e-9d39-df70a354930c_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanNameAxis_2bc19ab8-7963-424e-9d39-df70a354930c" xlink:to="loc_us-gaap_RetirementPlanNameDomain_2bc19ab8-7963-424e-9d39-df70a354930c_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanNameDomain_230c6c18-a337-4489-9711-cd2d6cd3168b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanNameAxis_2bc19ab8-7963-424e-9d39-df70a354930c" xlink:to="loc_us-gaap_RetirementPlanNameDomain_230c6c18-a337-4489-9711-cd2d6cd3168b" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_U.S.QualifiedPensionPlanMember_0abbcd08-c4ce-4829-8b07-5bd308393890" xlink:href="ppg-20201231.xsd#ppg_U.S.QualifiedPensionPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanNameDomain_230c6c18-a337-4489-9711-cd2d6cd3168b" xlink:to="loc_ppg_U.S.QualifiedPensionPlanMember_0abbcd08-c4ce-4829-8b07-5bd308393890" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_WelfareBenefitsU.S.Member_a7a0cb3a-bd5e-4ed9-86e2-460b22863b7e" xlink:href="ppg-20201231.xsd#ppg_WelfareBenefitsU.S.Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanNameDomain_230c6c18-a337-4489-9711-cd2d6cd3168b" xlink:to="loc_ppg_WelfareBenefitsU.S.Member_a7a0cb3a-bd5e-4ed9-86e2-460b22863b7e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_f21fe021-47d6-477f-ab02-7df2db51524d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureTable_ddfc9d73-4896-4a3c-b512-953666493c8c" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_f21fe021-47d6-477f-ab02-7df2db51524d" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_f21fe021-47d6-477f-ab02-7df2db51524d_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_f21fe021-47d6-477f-ab02-7df2db51524d" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_f21fe021-47d6-477f-ab02-7df2db51524d_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_8d8af0c8-a888-48f8-a066-25b07b61073c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_f21fe021-47d6-477f-ab02-7df2db51524d" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_8d8af0c8-a888-48f8-a066-25b07b61073c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_0034c910-5ebc-42d0-9e77-5196883e58eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_8d8af0c8-a888-48f8-a066-25b07b61073c" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_0034c910-5ebc-42d0-9e77-5196883e58eb" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_8b25d2ce-45d1-476f-aa8f-4449d5718134" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_8d8af0c8-a888-48f8-a066-25b07b61073c" xlink:to="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_8b25d2ce-45d1-476f-aa8f-4449d5718134" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_8e7bd492-0cd6-4dfc-8725-9f01e41e56d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPostretirementHealthCoverageMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_8d8af0c8-a888-48f8-a066-25b07b61073c" xlink:to="loc_us-gaap_DefinedBenefitPostretirementHealthCoverageMember_8e7bd492-0cd6-4dfc-8725-9f01e41e56d6" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_741245c8-478e-468f-a04a-c6786339fdb9" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureTable_ddfc9d73-4896-4a3c-b512-953666493c8c" xlink:to="loc_srt_StatementScenarioAxis_741245c8-478e-468f-a04a-c6786339fdb9" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_741245c8-478e-468f-a04a-c6786339fdb9_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementScenarioAxis_741245c8-478e-468f-a04a-c6786339fdb9" xlink:to="loc_srt_ScenarioUnspecifiedDomain_741245c8-478e-468f-a04a-c6786339fdb9_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_da113012-d87a-404b-a740-a5073da031e4" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementScenarioAxis_741245c8-478e-468f-a04a-c6786339fdb9" xlink:to="loc_srt_ScenarioUnspecifiedDomain_da113012-d87a-404b-a740-a5073da031e4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_09183ab3-257e-4020-961a-7ad94a4f218b" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioForecastMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ScenarioUnspecifiedDomain_da113012-d87a-404b-a740-a5073da031e4" xlink:to="loc_srt_ScenarioForecastMember_09183ab3-257e-4020-961a-7ad94a4f218b" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_4fe31a27-61c6-485f-928f-ad077f4c486f" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_PensionAndOtherPostretirementBenefitsDisclosureTable_ddfc9d73-4896-4a3c-b512-953666493c8c" xlink:to="loc_srt_RangeAxis_4fe31a27-61c6-485f-928f-ad077f4c486f" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_4fe31a27-61c6-485f-928f-ad077f4c486f_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_4fe31a27-61c6-485f-928f-ad077f4c486f" xlink:to="loc_srt_RangeMember_4fe31a27-61c6-485f-928f-ad077f4c486f_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_3f1c98c6-79ed-4a30-becd-6a47921065eb" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_4fe31a27-61c6-485f-928f-ad077f4c486f" xlink:to="loc_srt_RangeMember_3f1c98c6-79ed-4a30-becd-6a47921065eb" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_0236c3da-bfef-4671-bacc-1d33c813c9ef" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_3f1c98c6-79ed-4a30-becd-6a47921065eb" xlink:to="loc_srt_MinimumMember_0236c3da-bfef-4671-bacc-1d33c813c9ef" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_f2bf3ed5-6d60-44cf-b6d3-fecb09d38b52" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_3f1c98c6-79ed-4a30-becd-6a47921065eb" xlink:to="loc_srt_MaximumMember_f2bf3ed5-6d60-44cf-b6d3-fecb09d38b52" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansChangesinProjectedBenefitObligationsPlanAssetsandFundedStatusDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansChangesinProjectedBenefitObligationsPlanAssetsandFundedStatusDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansChangesinProjectedBenefitObligationsPlanAssetsandFundedStatusDetail" xlink:type="extended" id="ib2f4cec52e674d4d941c91baf2540db1_EmployeeBenefitPlansChangesinProjectedBenefitObligationsPlanAssetsandFundedStatusDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_15185b9c-f3d8-4aac-a87f-97da7eb739e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_15185b9c-f3d8-4aac-a87f-97da7eb739e1" xlink:to="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligation_ffec59e0-a786-4921-9560-1b0b10d82135" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanBenefitObligation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligation_ffec59e0-a786-4921-9560-1b0b10d82135" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanServiceCost_b62ef3e6-2bae-4616-a4fa-773c1a3367b3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanServiceCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_us-gaap_DefinedBenefitPlanServiceCost_b62ef3e6-2bae-4616-a4fa-773c1a3367b3" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanInterestCost_b8f9cff2-4671-4e0a-8346-d7ea2717e0fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanInterestCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_us-gaap_DefinedBenefitPlanInterestCost_b8f9cff2-4671-4e0a-8346-d7ea2717e0fd" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAmendments_90bb42da-afb1-4b59-bca0-2a3b64398681" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAmendments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAmendments_90bb42da-afb1-4b59-bca0-2a3b64398681" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanActuarialGainLoss_609f602b-9193-49d0-b6a3-466ca774a22e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanActuarialGainLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_us-gaap_DefinedBenefitPlanActuarialGainLoss_609f602b-9193-49d0-b6a3-466ca774a22e" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid_de98c7db-8f69-420b-987f-7871bcd9ff72" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligationBenefitsPaid_de98c7db-8f69-420b-987f-7871bcd9ff72" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanForeignCurrencyExchangeRateChangesBenefitObligation_0f387416-ee2a-44b2-8e44-6fddc1ed9dad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanForeignCurrencyExchangeRateChangesBenefitObligation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_us-gaap_DefinedBenefitPlanForeignCurrencyExchangeRateChangesBenefitObligation_0f387416-ee2a-44b2-8e44-6fddc1ed9dad" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanCurtailmentsAndSettlements_8f5b7db2-87d1-480b-9393-7b8061d92a4c" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanCurtailmentsAndSettlements"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_ppg_DefinedBenefitPlanCurtailmentsAndSettlements_8f5b7db2-87d1-480b-9393-7b8061d92a4c" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanOtherBenefitObligations_a861f7f2-161b-4191-8024-bb212a489d7c" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanOtherBenefitObligations"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInBenefitObligationRollForward_2ab70550-4ecc-45d5-a1f7-65bcd4c1c5ee" xlink:to="loc_ppg_DefinedBenefitPlanOtherBenefitObligations_a861f7f2-161b-4191-8024-bb212a489d7c" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligation_a17cbaab-8a7c-4a62-af6d-da94de302776" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanBenefitObligation"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_15185b9c-f3d8-4aac-a87f-97da7eb739e1" xlink:to="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_de6406d2-d3d0-43db-94aa-27092330badd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_de6406d2-d3d0-43db-94aa-27092330badd" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssets_fa94d1e3-f5f9-409d-98da-81c4596e4599" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanActualReturnOnPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:to="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssets_fa94d1e3-f5f9-409d-98da-81c4596e4599" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_9ecb6953-5aa0-479f-8c85-2ce107ebc225" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanContributionsByEmployer"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:to="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_9ecb6953-5aa0-479f-8c85-2ce107ebc225" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanFairValueOfPlanAssetsBenefitsPaid_814bb3de-b845-40a2-a29c-46a826fb6b80" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanFairValueOfPlanAssetsBenefitsPaid"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:to="loc_ppg_DefinedBenefitPlanFairValueOfPlanAssetsBenefitsPaid_814bb3de-b845-40a2-a29c-46a826fb6b80" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanSettlementsPlanAssets_ab44d278-c438-41a3-bf3b-bbb4fce9e074" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanSettlementsPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:to="loc_us-gaap_DefinedBenefitPlanSettlementsPlanAssets_ab44d278-c438-41a3-bf3b-bbb4fce9e074" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss_f75d9185-2347-4fcf-b7ab-0862bb818cd5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss_f75d9185-2347-4fcf-b7ab-0862bb818cd5" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PlanAssetsOtherChange_b07f1ab8-59b5-4f90-ad0e-11f466fb91dd" xlink:href="ppg-20201231.xsd#ppg_PlanAssetsOtherChange"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_301efecb-df3d-4baf-9e74-c167bfbb9f36" xlink:to="loc_ppg_PlanAssetsOtherChange_b07f1ab8-59b5-4f90-ad0e-11f466fb91dd" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_5db07fb3-7740-4cf2-a471-708280ef7f05" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFundedStatusOfPlan_7ae4bc6e-8fb3-44f9-ab79-4af8b167b0f4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFundedStatusOfPlan"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_15185b9c-f3d8-4aac-a87f-97da7eb739e1" xlink:to="loc_us-gaap_DefinedBenefitPlanFundedStatusOfPlan_7ae4bc6e-8fb3-44f9-ab79-4af8b167b0f4" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_76dd475b-3c38-4530-a65b-3de3e33b2985" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_15185b9c-f3d8-4aac-a87f-97da7eb739e1" xlink:to="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_76dd475b-3c38-4530-a65b-3de3e33b2985" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_f8fa0d9b-933b-4510-976e-28e11aae65a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_76dd475b-3c38-4530-a65b-3de3e33b2985" xlink:to="loc_us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_f8fa0d9b-933b-4510-976e-28e11aae65a6" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansCurrentLiabilities_0ff675d0-be8b-4dc7-bfe7-5afbf50d57eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansCurrentLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_76dd475b-3c38-4530-a65b-3de3e33b2985" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansCurrentLiabilities_0ff675d0-be8b-4dc7-bfe7-5afbf50d57eb" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementDefinedBenefitPlanLiabilitiesNoncurrent_d54a2dfb-4076-41d9-a673-e71ac8f672cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementDefinedBenefitPlanLiabilitiesNoncurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_76dd475b-3c38-4530-a65b-3de3e33b2985" xlink:to="loc_us-gaap_OtherPostretirementDefinedBenefitPlanLiabilitiesNoncurrent_d54a2dfb-4076-41d9-a673-e71ac8f672cf" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPensionPlanLiabilitiesNoncurrent_866bee1f-202f-492c-8e61-53d61fbb953f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPensionPlanLiabilitiesNoncurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_76dd475b-3c38-4530-a65b-3de3e33b2985" xlink:to="loc_us-gaap_DefinedBenefitPensionPlanLiabilitiesNoncurrent_866bee1f-202f-492c-8e61-53d61fbb953f" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_9e7e9791-d01a-4d1d-9dba-3040f8c3a959" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheetAbstract_76dd475b-3c38-4530-a65b-3de3e33b2985" xlink:to="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_9e7e9791-d01a-4d1d-9dba-3040f8c3a959" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_05a2e03e-0096-4ed2-84a9-bbcef173239a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_15185b9c-f3d8-4aac-a87f-97da7eb739e1" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_05a2e03e-0096-4ed2-84a9-bbcef173239a" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationAxis_5c02a838-beb1-42f1-9277-1f38a4fa9515" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_05a2e03e-0096-4ed2-84a9-bbcef173239a" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationAxis_5c02a838-beb1-42f1-9277-1f38a4fa9515" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_5c02a838-beb1-42f1-9277-1f38a4fa9515_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_5c02a838-beb1-42f1-9277-1f38a4fa9515" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_5c02a838-beb1-42f1-9277-1f38a4fa9515_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_14f16bb9-a832-4585-bf36-0ca3ddc6ce42" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_5c02a838-beb1-42f1-9277-1f38a4fa9515" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_14f16bb9-a832-4585-bf36-0ca3ddc6ce42" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticPlanMember_84a547a0-b361-4586-906e-92c26a03ec87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_14f16bb9-a832-4585-bf36-0ca3ddc6ce42" xlink:to="loc_us-gaap_DomesticPlanMember_84a547a0-b361-4586-906e-92c26a03ec87" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_country_US_24de706d-1744-4516-8a96-4c822da047f2" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_US"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DomesticPlanMember_84a547a0-b361-4586-906e-92c26a03ec87" xlink:to="loc_country_US_24de706d-1744-4516-8a96-4c822da047f2" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignPlanMember_01f8e792-fd29-4155-af0b-87e13376f4d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_14f16bb9-a832-4585-bf36-0ca3ddc6ce42" xlink:to="loc_us-gaap_ForeignPlanMember_01f8e792-fd29-4155-af0b-87e13376f4d4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_6798ca8d-ba64-457f-83a9-ca0e30ed237d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_05a2e03e-0096-4ed2-84a9-bbcef173239a" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_6798ca8d-ba64-457f-83a9-ca0e30ed237d" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_6798ca8d-ba64-457f-83a9-ca0e30ed237d_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_6798ca8d-ba64-457f-83a9-ca0e30ed237d" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_6798ca8d-ba64-457f-83a9-ca0e30ed237d_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_28ac293f-2652-4e32-9eda-8df299f3bb7b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_6798ca8d-ba64-457f-83a9-ca0e30ed237d" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_28ac293f-2652-4e32-9eda-8df299f3bb7b" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_ca7dc788-ead7-4535-9e8b-ce2dc583d6b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_28ac293f-2652-4e32-9eda-8df299f3bb7b" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_ca7dc788-ead7-4535-9e8b-ce2dc583d6b7" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_1bff5508-2735-4df2-97ee-7b32d460f77e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_28ac293f-2652-4e32-9eda-8df299f3bb7b" xlink:to="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_1bff5508-2735-4df2-97ee-7b32d460f77e" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansAccumulatedOtherComprehensiveLossPretaxAmountsNotYetReflectedinNetPeriodicBenefitCostDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansAccumulatedOtherComprehensiveLossPretaxAmountsNotYetReflectedinNetPeriodicBenefitCostDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansAccumulatedOtherComprehensiveLossPretaxAmountsNotYetReflectedinNetPeriodicBenefitCostDetails" xlink:type="extended" id="iaa36a65c43484672a401007a1593b456_EmployeeBenefitPlansAccumulatedOtherComprehensiveLossPretaxAmountsNotYetReflectedinNetPeriodicBenefitCostDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_0101fbee-ddf6-4b5b-9ad9-a0349273a092" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesBeforeTax_e1944681-2e3e-4969-9dcd-6fc367cafb26" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_0101fbee-ddf6-4b5b-9ad9-a0349273a092" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesBeforeTax_e1944681-2e3e-4969-9dcd-6fc367cafb26" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditBeforeTax_9a5f2846-1bfd-4bae-ab34-83db035323f7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_0101fbee-ddf6-4b5b-9ad9-a0349273a092" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditBeforeTax_9a5f2846-1bfd-4bae-ab34-83db035323f7" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTax_88b167ee-ece5-4926-b81b-87b1673433e2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_0101fbee-ddf6-4b5b-9ad9-a0349273a092" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTax_88b167ee-ece5-4926-b81b-87b1673433e2" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_12895ab9-76bf-4bc3-9b71-fcd31aa4682e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_0101fbee-ddf6-4b5b-9ad9-a0349273a092" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_12895ab9-76bf-4bc3-9b71-fcd31aa4682e" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_ff6b4fdd-36cd-4f60-bacc-c4661f54be5f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_12895ab9-76bf-4bc3-9b71-fcd31aa4682e" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_ff6b4fdd-36cd-4f60-bacc-c4661f54be5f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_ff6b4fdd-36cd-4f60-bacc-c4661f54be5f_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_ff6b4fdd-36cd-4f60-bacc-c4661f54be5f" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_ff6b4fdd-36cd-4f60-bacc-c4661f54be5f_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_09ac1d94-f4ca-4ddd-8545-703038356e51" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_ff6b4fdd-36cd-4f60-bacc-c4661f54be5f" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_09ac1d94-f4ca-4ddd-8545-703038356e51" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_14cdeb85-5554-4ca8-8265-6d40ba6346eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_09ac1d94-f4ca-4ddd-8545-703038356e51" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_14cdeb85-5554-4ca8-8265-6d40ba6346eb" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_02dff72c-af5b-47df-af18-691d91007005" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_09ac1d94-f4ca-4ddd-8545-703038356e51" xlink:to="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_02dff72c-af5b-47df-af18-691d91007005" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansChangeinAccumulatedOtherComprehensiveLossPretaxRelatingtoDefinedBenefitPensionandOtherPostretirementBenefitsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansChangeinAccumulatedOtherComprehensiveLossPretaxRelatingtoDefinedBenefitPensionandOtherPostretirementBenefitsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansChangeinAccumulatedOtherComprehensiveLossPretaxRelatingtoDefinedBenefitPensionandOtherPostretirementBenefitsDetail" xlink:type="extended" id="idef16542ccce4e0e8ff3fb9a3a44aa77_EmployeeBenefitPlansChangeinAccumulatedOtherComprehensiveLossPretaxRelatingtoDefinedBenefitPensionandOtherPostretirementBenefitsDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax_0a08524d-c3f4-4071-9f75-4bc01229d47d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax_0a08524d-c3f4-4071-9f75-4bc01229d47d" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostCreditArisingDuringPeriodBeforeTax_a025b28c-ae1a-4ac7-b013-2a9d440b54f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostCreditArisingDuringPeriodBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlanNetPriorServiceCostCreditArisingDuringPeriodBeforeTax_a025b28c-ae1a-4ac7-b013-2a9d440b54f9" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_5ee4a3a8-ed8d-4c0e-9734-d3040ec62c14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_5ee4a3a8-ed8d-4c0e-9734-d3040ec62c14" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditBeforeTax_55d732d5-24b2-48d7-824f-7b87cbce9656" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditBeforeTax_55d732d5-24b2-48d7-824f-7b87cbce9656" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_OtherComprehensiveIncomeDefinedBenefitPlanCurrencyTranslationBeforeTax_04d199b5-df42-438a-8cad-2d0b25224eb3" xlink:href="ppg-20201231.xsd#ppg_OtherComprehensiveIncomeDefinedBenefitPlanCurrencyTranslationBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_ppg_OtherComprehensiveIncomeDefinedBenefitPlanCurrencyTranslationBeforeTax_04d199b5-df42-438a-8cad-2d0b25224eb3" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossFinalizationOfPensionAndNonPensionPostretirementPlanValuationBeforeTax_aae0ccb3-8a06-4654-adcb-d35b10094203" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossFinalizationOfPensionAndNonPensionPostretirementPlanValuationBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossFinalizationOfPensionAndNonPensionPostretirementPlanValuationBeforeTax_aae0ccb3-8a06-4654-adcb-d35b10094203" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeTax_09752952-53ba-406c-8465-1092443b5b32" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentBeforeTax_09752952-53ba-406c-8465-1092443b5b32" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_8e0bd8f3-94de-4941-94e1-f11ee2f7e8db" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1a0e42ae-bd51-4399-bcb1-f98bcadfe173" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_8e0bd8f3-94de-4941-94e1-f11ee2f7e8db" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_147ba530-f8a2-48d3-b5af-20df1634c4db" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_8e0bd8f3-94de-4941-94e1-f11ee2f7e8db" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_147ba530-f8a2-48d3-b5af-20df1634c4db" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_147ba530-f8a2-48d3-b5af-20df1634c4db_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_147ba530-f8a2-48d3-b5af-20df1634c4db" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_147ba530-f8a2-48d3-b5af-20df1634c4db_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_c5b7a0f6-179f-4214-ad13-3e979c259e4e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_147ba530-f8a2-48d3-b5af-20df1634c4db" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_c5b7a0f6-179f-4214-ad13-3e979c259e4e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_1c60c78f-5e3f-42ae-bad4-b8d81a397f0d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_c5b7a0f6-179f-4214-ad13-3e979c259e4e" xlink:to="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_1c60c78f-5e3f-42ae-bad4-b8d81a397f0d" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_adca59fc-7663-4f7b-b2df-ac43cf6b2c62" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_c5b7a0f6-179f-4214-ad13-3e979c259e4e" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_adca59fc-7663-4f7b-b2df-ac43cf6b2c62" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansNetPeriodicBenefitCostsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansNetPeriodicBenefitCostsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansNetPeriodicBenefitCostsDetail" xlink:type="extended" id="i048c826ca78747ebabed34e2a0e3cb33_EmployeeBenefitPlansNetPeriodicBenefitCostsDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanServiceCost_e008ab11-8b8d-40fe-aa0d-678687c5dd93" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanServiceCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_DefinedBenefitPlanServiceCost_e008ab11-8b8d-40fe-aa0d-678687c5dd93" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanInterestCost_d49e2b87-aa30-499a-b45e-9c99b5812efc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanInterestCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_DefinedBenefitPlanInterestCost_d49e2b87-aa30-499a-b45e-9c99b5812efc" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_dadc0133-9e5c-45f8-8eef-c7cfaee24499" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_dadc0133-9e5c-45f8-8eef-c7cfaee24499" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditBeforeTax_dd446654-aada-4890-87e4-83315764c106" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossAmortizationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetPriorServiceCostCreditBeforeTax_dd446654-aada-4890-87e4-83315764c106" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_49a9a59e-b608-4ccd-bdda-f68e0951145b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_49a9a59e-b608-4ccd-bdda-f68e0951145b" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1_c6c8a97e-c14b-4dbd-b736-ef5f0c48401d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1_c6c8a97e-c14b-4dbd-b736-ef5f0c48401d" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_6530d6ba-c215-4fa3-aedb-7ede4feae9eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_6530d6ba-c215-4fa3-aedb-7ede4feae9eb" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_64731ce8-cfe6-4ae1-9695-ac273421422d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_12122776-da9a-4e2b-9f9b-de4d6a4ac7c6" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_64731ce8-cfe6-4ae1-9695-ac273421422d" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_974a5b7e-f51c-4b99-b926-25e7c92b0452" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_64731ce8-cfe6-4ae1-9695-ac273421422d" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_974a5b7e-f51c-4b99-b926-25e7c92b0452" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_974a5b7e-f51c-4b99-b926-25e7c92b0452_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_974a5b7e-f51c-4b99-b926-25e7c92b0452" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_974a5b7e-f51c-4b99-b926-25e7c92b0452_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_aa535763-d7db-4c48-8dcc-36e17bd7b7cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_974a5b7e-f51c-4b99-b926-25e7c92b0452" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_aa535763-d7db-4c48-8dcc-36e17bd7b7cf" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_4cccb5fa-8642-4f34-8437-f70b55b9beee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_aa535763-d7db-4c48-8dcc-36e17bd7b7cf" xlink:to="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_4cccb5fa-8642-4f34-8437-f70b55b9beee" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_d3097ba3-6544-4979-aca5-07d3386614e3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_aa535763-d7db-4c48-8dcc-36e17bd7b7cf" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_d3097ba3-6544-4979-aca5-07d3386614e3" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineBenefitObligationforDefinedBenefitPensionandOtherPostretirementPlansDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineBenefitObligationforDefinedBenefitPensionandOtherPostretirementPlansDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineBenefitObligationforDefinedBenefitPensionandOtherPostretirementPlansDetail" xlink:type="extended" id="i2872ca571a214660a89df18409451d09_EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineBenefitObligationforDefinedBenefitPensionandOtherPostretirementPlansDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1792c654-f619-4eb1-9c47-f9a706873061" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate_b65d6303-28c2-4ad8-a9ab-77cfc4804b2e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1792c654-f619-4eb1-9c47-f9a706873061" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate_b65d6303-28c2-4ad8-a9ab-77cfc4804b2e" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationRateOfCompensationIncrease_c443d56a-20d3-4999-9bfd-feeb93073041" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationRateOfCompensationIncrease"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1792c654-f619-4eb1-9c47-f9a706873061" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationRateOfCompensationIncrease_c443d56a-20d3-4999-9bfd-feeb93073041" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets_211d5c2d-2809-4929-831f-2ee0c22efea3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1792c654-f619-4eb1-9c47-f9a706873061" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostExpectedLongTermReturnOnAssets_211d5c2d-2809-4929-831f-2ee0c22efea3" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4431b5d1-a4a8-4359-977a-8a5bb30b9587" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_1792c654-f619-4eb1-9c47-f9a706873061" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4431b5d1-a4a8-4359-977a-8a5bb30b9587" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationAxis_6e7ebbac-5cc7-49a6-9c1f-4b8aa5b2839a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4431b5d1-a4a8-4359-977a-8a5bb30b9587" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationAxis_6e7ebbac-5cc7-49a6-9c1f-4b8aa5b2839a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_6e7ebbac-5cc7-49a6-9c1f-4b8aa5b2839a_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_6e7ebbac-5cc7-49a6-9c1f-4b8aa5b2839a" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_6e7ebbac-5cc7-49a6-9c1f-4b8aa5b2839a_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_506848ea-9858-458a-b19b-1b98cde77009" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_6e7ebbac-5cc7-49a6-9c1f-4b8aa5b2839a" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_506848ea-9858-458a-b19b-1b98cde77009" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticPlanMember_a13a1039-867e-4c21-a2a1-ab0b6142d01c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_506848ea-9858-458a-b19b-1b98cde77009" xlink:to="loc_us-gaap_DomesticPlanMember_a13a1039-867e-4c21-a2a1-ab0b6142d01c" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_country_US_5ced7dce-3419-4cd6-8cfb-ed0e42813720" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_US"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DomesticPlanMember_a13a1039-867e-4c21-a2a1-ab0b6142d01c" xlink:to="loc_country_US_5ced7dce-3419-4cd6-8cfb-ed0e42813720" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignPlanMember_b026477f-bf65-4c95-aa56-9c8eb0ef538d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ForeignPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_506848ea-9858-458a-b19b-1b98cde77009" xlink:to="loc_us-gaap_ForeignPlanMember_b026477f-bf65-4c95-aa56-9c8eb0ef538d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_2f02f9cc-b83e-474d-be41-99a3dd511b30" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4431b5d1-a4a8-4359-977a-8a5bb30b9587" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_2f02f9cc-b83e-474d-be41-99a3dd511b30" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_2f02f9cc-b83e-474d-be41-99a3dd511b30_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_2f02f9cc-b83e-474d-be41-99a3dd511b30" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_2f02f9cc-b83e-474d-be41-99a3dd511b30_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_f32a6bcb-9907-4629-86cb-01def8abf8a8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_2f02f9cc-b83e-474d-be41-99a3dd511b30" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_f32a6bcb-9907-4629-86cb-01def8abf8a8" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_8f6b24da-f6de-42e3-9dbf-270385ef3739" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_f32a6bcb-9907-4629-86cb-01def8abf8a8" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_8f6b24da-f6de-42e3-9dbf-270385ef3739" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_f9ba1bb7-f2d6-4082-93ac-597e3c3bb885" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_f32a6bcb-9907-4629-86cb-01def8abf8a8" xlink:to="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_f9ba1bb7-f2d6-4082-93ac-597e3c3bb885" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_f71e9e1e-caeb-40d2-8968-f4fae73346f7" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4431b5d1-a4a8-4359-977a-8a5bb30b9587" xlink:to="loc_srt_RangeAxis_f71e9e1e-caeb-40d2-8968-f4fae73346f7" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_f71e9e1e-caeb-40d2-8968-f4fae73346f7_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_f71e9e1e-caeb-40d2-8968-f4fae73346f7" xlink:to="loc_srt_RangeMember_f71e9e1e-caeb-40d2-8968-f4fae73346f7_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01850477-f90c-4be3-a1d5-72c2f636f7dc" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_f71e9e1e-caeb-40d2-8968-f4fae73346f7" xlink:to="loc_srt_RangeMember_01850477-f90c-4be3-a1d5-72c2f636f7dc" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_f7d2b8a5-fb8d-4a3f-bd4e-37039616fef7" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_01850477-f90c-4be3-a1d5-72c2f636f7dc" xlink:to="loc_srt_MinimumMember_f7d2b8a5-fb8d-4a3f-bd4e-37039616fef7" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_84d8e030-3406-40ab-bce5-7a28b09f34ef" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_01850477-f90c-4be3-a1d5-72c2f636f7dc" xlink:to="loc_srt_MaximumMember_84d8e030-3406-40ab-bce5-7a28b09f34ef" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineNetPeriodicBenefitCostforDefinedBenefitPensionandOtherPostretirementPlansDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineNetPeriodicBenefitCostforDefinedBenefitPensionandOtherPostretirementPlansDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineNetPeriodicBenefitCostforDefinedBenefitPensionandOtherPostretirementPlansDetail" xlink:type="extended" id="i6df4c6fc49bd4fa98c247accc4b1e217_EmployeeBenefitPlansWeightedAverageAssumptionsUsedtoDetermineNetPeriodicBenefitCostforDefinedBenefitPensionandOtherPostretirementPlansDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_568390ea-30ae-4db8-a3fc-14dd93bc45ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate_67c9397a-fef8-49aa-84c0-bd0a7c3d83a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_568390ea-30ae-4db8-a3fc-14dd93bc45ed" xlink:to="loc_us-gaap_DefinedBenefitPlanAssumptionsUsedCalculatingBenefitObligationDiscountRate_67c9397a-fef8-49aa-84c0-bd0a7c3d83a9" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_6e2f2937-ddda-48f9-9b0a-7037c5303b39" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansTableTextBlockLineItems_568390ea-30ae-4db8-a3fc-14dd93bc45ed" xlink:to="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_6e2f2937-ddda-48f9-9b0a-7037c5303b39" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeAxis_6e50b150-4590-41c6-9008-34b233690355" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_6e2f2937-ddda-48f9-9b0a-7037c5303b39" xlink:to="loc_us-gaap_RetirementPlanTypeAxis_6e50b150-4590-41c6-9008-34b233690355" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_6e50b150-4590-41c6-9008-34b233690355_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_6e50b150-4590-41c6-9008-34b233690355" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_6e50b150-4590-41c6-9008-34b233690355_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanTypeDomain_a4cb2644-e9a1-42bd-acbc-e303e665c08a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanTypeDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanTypeAxis_6e50b150-4590-41c6-9008-34b233690355" xlink:to="loc_us-gaap_RetirementPlanTypeDomain_a4cb2644-e9a1-42bd-acbc-e303e665c08a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionPlansDefinedBenefitMember_57355750-9e93-48b3-a776-66b41f886795" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PensionPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_a4cb2644-e9a1-42bd-acbc-e303e665c08a" xlink:to="loc_us-gaap_PensionPlansDefinedBenefitMember_57355750-9e93-48b3-a776-66b41f886795" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_8bf74de7-5810-4a27-a8c7-909ba2956c11" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanTypeDomain_a4cb2644-e9a1-42bd-acbc-e303e665c08a" xlink:to="loc_us-gaap_OtherPostretirementBenefitPlansDefinedBenefitMember_8bf74de7-5810-4a27-a8c7-909ba2956c11" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationAxis_1286691e-cc44-4116-a340-5d4f1a26eb89" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DefinedBenefitPlansAndOtherPostretirementBenefitPlansDisclosuresTable_6e2f2937-ddda-48f9-9b0a-7037c5303b39" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationAxis_1286691e-cc44-4116-a340-5d4f1a26eb89" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_1286691e-cc44-4116-a340-5d4f1a26eb89_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_1286691e-cc44-4116-a340-5d4f1a26eb89" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_1286691e-cc44-4116-a340-5d4f1a26eb89_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_5dc7f4d8-2a89-4ef6-b1b5-2830f32a12e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_1286691e-cc44-4116-a340-5d4f1a26eb89" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_5dc7f4d8-2a89-4ef6-b1b5-2830f32a12e9" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticPlanMember_a3978b03-27f9-4739-9b53-ed54b7d1301d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_5dc7f4d8-2a89-4ef6-b1b5-2830f32a12e9" xlink:to="loc_us-gaap_DomesticPlanMember_a3978b03-27f9-4739-9b53-ed54b7d1301d" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_country_US_87d920b6-eb30-4e46-992e-cc0ce9f33758" xlink:href="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd#country_US"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DomesticPlanMember_a3978b03-27f9-4739-9b53-ed54b7d1301d" xlink:to="loc_country_US_87d920b6-eb30-4e46-992e-cc0ce9f33758" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansWeightedAverageTargetPensionPlanAssetAllocationsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansWeightedAverageTargetPensionPlanAssetAllocationsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansWeightedAverageTargetPensionPlanAssetAllocationsDetail" xlink:type="extended" id="if3e0c9b9a57e41e9a01e7b5b1de04658_EmployeeBenefitPlansWeightedAverageTargetPensionPlanAssetAllocationsDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_dfcf63a7-50a4-4c12-9899-8a220b7e85a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract_45b3f39a-46b8-4bc1-83a8-21722c4961b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_dfcf63a7-50a4-4c12-9899-8a220b7e85a9" xlink:to="loc_us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract_45b3f39a-46b8-4bc1-83a8-21722c4961b4" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAssetsTargetAllocationPercentage_c2dab6b9-dca9-4396-9406-5656f756a795" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAssetsTargetAllocationPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanAssetsTargetAllocationsAbstract_45b3f39a-46b8-4bc1-83a8-21722c4961b4" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAssetsTargetAllocationPercentage_c2dab6b9-dca9-4396-9406-5656f756a795" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_6f7f26e2-2c95-48c4-acb9-a6635e15e68f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_dfcf63a7-50a4-4c12-9899-8a220b7e85a9" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_6f7f26e2-2c95-48c4-acb9-a6635e15e68f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_94a5bdd9-cea2-4954-a95c-dfccb09876fe" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_6f7f26e2-2c95-48c4-acb9-a6635e15e68f" xlink:to="loc_srt_RangeAxis_94a5bdd9-cea2-4954-a95c-dfccb09876fe" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_94a5bdd9-cea2-4954-a95c-dfccb09876fe_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_94a5bdd9-cea2-4954-a95c-dfccb09876fe" xlink:to="loc_srt_RangeMember_94a5bdd9-cea2-4954-a95c-dfccb09876fe_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_dd137105-7f9a-4570-b2d3-876df5039d6a" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_94a5bdd9-cea2-4954-a95c-dfccb09876fe" xlink:to="loc_srt_RangeMember_dd137105-7f9a-4570-b2d3-876df5039d6a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_d28f6c22-f703-4624-afb0-3c11a1bbf106" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_dd137105-7f9a-4570-b2d3-876df5039d6a" xlink:to="loc_srt_MinimumMember_d28f6c22-f703-4624-afb0-3c11a1bbf106" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_4de1ed81-6f2b-4bac-8e45-9f9f60f231e4" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_dd137105-7f9a-4570-b2d3-876df5039d6a" xlink:to="loc_srt_MaximumMember_4de1ed81-6f2b-4bac-8e45-9f9f60f231e4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_c7af662d-e0f4-4b69-83c4-7497cd10c2d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_6f7f26e2-2c95-48c4-acb9-a6635e15e68f" xlink:to="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_c7af662d-e0f4-4b69-83c4-7497cd10c2d3" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_c7af662d-e0f4-4b69-83c4-7497cd10c2d3_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_c7af662d-e0f4-4b69-83c4-7497cd10c2d3" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_c7af662d-e0f4-4b69-83c4-7497cd10c2d3_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_df441cd7-e225-4a35-9fa0-1de2dddfd608" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_c7af662d-e0f4-4b69-83c4-7497cd10c2d3" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_df441cd7-e225-4a35-9fa0-1de2dddfd608" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesMember_0e6acd29-2638-4aaa-9ed0-87d3c23ccf0e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanEquitySecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_df441cd7-e225-4a35-9fa0-1de2dddfd608" xlink:to="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesMember_0e6acd29-2638-4aaa-9ed0-87d3c23ccf0e" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDebtSecurityMember_1177e29f-66e2-4873-90a4-a0569115810e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDebtSecurityMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_df441cd7-e225-4a35-9fa0-1de2dddfd608" xlink:to="loc_us-gaap_DefinedBenefitPlanDebtSecurityMember_1177e29f-66e2-4873-90a4-a0569115810e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanRealEstateMember_e121c97b-53b0-4e2c-b946-20ce3c9ebab7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanRealEstateMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_df441cd7-e225-4a35-9fa0-1de2dddfd608" xlink:to="loc_us-gaap_DefinedBenefitPlanRealEstateMember_e121c97b-53b0-4e2c-b946-20ce3c9ebab7" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanOtherAssetsMember_4ca69a3c-04b0-4837-995a-1a5b0ec5e6e2" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanOtherAssetsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_df441cd7-e225-4a35-9fa0-1de2dddfd608" xlink:to="loc_ppg_DefinedBenefitPlanOtherAssetsMember_4ca69a3c-04b0-4837-995a-1a5b0ec5e6e2" xlink:type="arc" order="3"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansFairValuesoftheCompanysPensionPlanAssetsbyAssetCategoryDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansFairValuesoftheCompanysPensionPlanAssetsbyAssetCategoryDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansFairValuesoftheCompanysPensionPlanAssetsbyAssetCategoryDetail" xlink:type="extended" id="i6038e80746ce4274a11677b53044192e_EmployeeBenefitPlansFairValuesoftheCompanysPensionPlanAssetsbyAssetCategoryDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_585e51de-22e3-4bc5-b315-6925ee7622eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_2164303e-0959-4c8f-9292-fb27b6f1458c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_585e51de-22e3-4bc5-b315-6925ee7622eb" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_2164303e-0959-4c8f-9292-fb27b6f1458c" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4c0d6bbb-c900-49c3-b77b-e8a72979426f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_585e51de-22e3-4bc5-b315-6925ee7622eb" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4c0d6bbb-c900-49c3-b77b-e8a72979426f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_a9fe3711-4bc7-46bf-8886-74900d061f15" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4c0d6bbb-c900-49c3-b77b-e8a72979426f" xlink:to="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_a9fe3711-4bc7-46bf-8886-74900d061f15" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_a9fe3711-4bc7-46bf-8886-74900d061f15_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_a9fe3711-4bc7-46bf-8886-74900d061f15" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_a9fe3711-4bc7-46bf-8886-74900d061f15_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_a9fe3711-4bc7-46bf-8886-74900d061f15" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesUsLargeCapMember_0be790bf-ce8f-4304-a3dc-39cd207b1ed5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanEquitySecuritiesUsLargeCapMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesUsLargeCapMember_0be790bf-ce8f-4304-a3dc-39cd207b1ed5" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesUsSmallCapMember_920ed5ce-ada2-4e45-a3b4-10d245cb218d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanEquitySecuritiesUsSmallCapMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesUsSmallCapMember_920ed5ce-ada2-4e45-a3b4-10d245cb218d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesNonUsMember_620ccb81-d46c-4cdd-ada3-7b695a373c60" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanEquitySecuritiesNonUsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_us-gaap_DefinedBenefitPlanEquitySecuritiesNonUsMember_620ccb81-d46c-4cdd-ada3-7b695a373c60" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember_94e93884-f526-46f2-a80a-b7156c763c7c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_us-gaap_DefinedBenefitPlanCashAndCashEquivalentsMember_94e93884-f526-46f2-a80a-b7156c763c7c" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticCorporateDebtSecuritiesMember_448d1cb7-af6c-46f5-b5d6-b0b876654a2a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticCorporateDebtSecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_us-gaap_DomesticCorporateDebtSecuritiesMember_448d1cb7-af6c-46f5-b5d6-b0b876654a2a" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtSecurityDevelopedMarketsAndEmergingEconomiesMember_46578e12-bbe1-405e-9a56-76d16c99caee" xlink:href="ppg-20201231.xsd#ppg_DebtSecurityDevelopedMarketsAndEmergingEconomiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_ppg_DebtSecurityDevelopedMarketsAndEmergingEconomiesMember_46578e12-bbe1-405e-9a56-76d16c99caee" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DebtSecurityDiversePortfolioMember_507f927e-2140-4994-8563-55a1bbf2bd76" xlink:href="ppg-20201231.xsd#ppg_DebtSecurityDiversePortfolioMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_ppg_DebtSecurityDiversePortfolioMember_507f927e-2140-4994-8563-55a1bbf2bd76" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_41d107b6-4db5-4043-89c6-04b1b5a71146" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_41d107b6-4db5-4043-89c6-04b1b5a71146" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DevelopedMarketsGovernmentAgenciesDebtSecuritiesMember_ff403e11-9859-4d37-8b3d-a5c4d2393b09" xlink:href="ppg-20201231.xsd#ppg_DevelopedMarketsGovernmentAgenciesDebtSecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_ppg_DevelopedMarketsGovernmentAgenciesDebtSecuritiesMember_ff403e11-9859-4d37-8b3d-a5c4d2393b09" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_MortgageBackedAssetBackedDebtSecuritiesMunicipalBondsOtherDebtSecuritiesIncludingDerivativesMember_cd178294-8b28-4943-a2e2-2742996a4477" xlink:href="ppg-20201231.xsd#ppg_MortgageBackedAssetBackedDebtSecuritiesMunicipalBondsOtherDebtSecuritiesIncludingDerivativesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_ppg_MortgageBackedAssetBackedDebtSecuritiesMunicipalBondsOtherDebtSecuritiesIncludingDerivativesMember_cd178294-8b28-4943-a2e2-2742996a4477" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedBenefitPlanRealEstateHedgeFundsAndOtherMember_d8fefb67-abee-41b9-90a2-aae184ceba21" xlink:href="ppg-20201231.xsd#ppg_DefinedBenefitPlanRealEstateHedgeFundsAndOtherMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_2e80eb6e-0ba2-4a0b-9f40-12e2d32e0c6e" xlink:to="loc_ppg_DefinedBenefitPlanRealEstateHedgeFundsAndOtherMember_d8fefb67-abee-41b9-90a2-aae184ceba21" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_cd1ae5e2-6d2a-4e1b-91e2-56656faa04e4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_4c0d6bbb-c900-49c3-b77b-e8a72979426f" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_cd1ae5e2-6d2a-4e1b-91e2-56656faa04e4" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_cd1ae5e2-6d2a-4e1b-91e2-56656faa04e4_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_cd1ae5e2-6d2a-4e1b-91e2-56656faa04e4" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_cd1ae5e2-6d2a-4e1b-91e2-56656faa04e4_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2cbdd626-d0dd-4edc-a663-77032e3f9b91" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_cd1ae5e2-6d2a-4e1b-91e2-56656faa04e4" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2cbdd626-d0dd-4edc-a663-77032e3f9b91" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel12And3Member_372d8926-a06e-455c-9523-cf90a09698ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel12And3Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2cbdd626-d0dd-4edc-a663-77032e3f9b91" xlink:to="loc_us-gaap_FairValueInputsLevel12And3Member_372d8926-a06e-455c-9523-cf90a09698ef" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_9bb8c5a1-5969-4df1-9448-9a312e0fcb1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueInputsLevel12And3Member_372d8926-a06e-455c-9523-cf90a09698ef" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_9bb8c5a1-5969-4df1-9448-9a312e0fcb1a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_ee31f30b-f39c-4aa4-890c-1f656efa7893" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueInputsLevel12And3Member_372d8926-a06e-455c-9523-cf90a09698ef" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_ee31f30b-f39c-4aa4-890c-1f656efa7893" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_6f78169c-f133-48a3-9ae7-11092eb21692" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueInputsLevel12And3Member_372d8926-a06e-455c-9523-cf90a09698ef" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_6f78169c-f133-48a3-9ae7-11092eb21692" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_7fdba132-a342-484f-b8ed-66059f717921" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2cbdd626-d0dd-4edc-a663-77032e3f9b91" xlink:to="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_7fdba132-a342-484f-b8ed-66059f717921" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansChangeinFairValueofCompanysLevel3PensionAssetsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansChangeinFairValueofCompanysLevel3PensionAssetsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansChangeinFairValueofCompanysLevel3PensionAssetsDetail" xlink:type="extended" id="i9e38537a371a484784bead1f036dea13_EmployeeBenefitPlansChangeinFairValueofCompanysLevel3PensionAssetsDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_b02d00a9-11be-4b76-9d0e-5067da713e3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_5d514dc5-e1e9-468e-a624-932f9217ec99" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_b02d00a9-11be-4b76-9d0e-5067da713e3c" xlink:to="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_5d514dc5-e1e9-468e-a624-932f9217ec99" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_80789dfa-f620-40bb-8091-5a2963783617" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_5d514dc5-e1e9-468e-a624-932f9217ec99" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_80789dfa-f620-40bb-8091-5a2963783617" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssetsSoldDuringPeriod_351f0030-bd29-4308-93ba-c1b86d5a701d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanActualReturnOnPlanAssetsSoldDuringPeriod"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_5d514dc5-e1e9-468e-a624-932f9217ec99" xlink:to="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssetsSoldDuringPeriod_351f0030-bd29-4308-93ba-c1b86d5a701d" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssetsStillHeld_3028d0e2-5f5b-495e-a376-12eb1e35fef0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanActualReturnOnPlanAssetsStillHeld"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_5d514dc5-e1e9-468e-a624-932f9217ec99" xlink:to="loc_us-gaap_DefinedBenefitPlanActualReturnOnPlanAssetsStillHeld_3028d0e2-5f5b-495e-a376-12eb1e35fef0" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanTransfersBetweenMeasurementLevels_dc619c76-79c7-4df4-b773-e95bcb674e19" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanTransfersBetweenMeasurementLevels"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_5d514dc5-e1e9-468e-a624-932f9217ec99" xlink:to="loc_us-gaap_DefinedBenefitPlanTransfersBetweenMeasurementLevels_dc619c76-79c7-4df4-b773-e95bcb674e19" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss_a238f3bb-407a-4555-88af-d99c815be34c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_5d514dc5-e1e9-468e-a624-932f9217ec99" xlink:to="loc_us-gaap_DefinedBenefitPlanPlanAssetsForeignCurrencyTranslationGainLoss_a238f3bb-407a-4555-88af-d99c815be34c" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_4c6b3d98-e960-4ad2-a101-7345ef863dd6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_1a38eba7-4c1a-4b51-b698-f254f4da20a0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_b02d00a9-11be-4b76-9d0e-5067da713e3c" xlink:to="loc_us-gaap_StatementTable_1a38eba7-4c1a-4b51-b698-f254f4da20a0" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_fc146c7f-2be7-4197-8966-7a3536c150c4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_1a38eba7-4c1a-4b51-b698-f254f4da20a0" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_fc146c7f-2be7-4197-8966-7a3536c150c4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_fc146c7f-2be7-4197-8966-7a3536c150c4_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_fc146c7f-2be7-4197-8966-7a3536c150c4" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_fc146c7f-2be7-4197-8966-7a3536c150c4_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_53c80970-3979-4f1d-a8c8-fdde3ca18e19" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_fc146c7f-2be7-4197-8966-7a3536c150c4" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_53c80970-3979-4f1d-a8c8-fdde3ca18e19" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_dd1cfa38-0086-49fa-8da8-4418a3a4a89c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_53c80970-3979-4f1d-a8c8-fdde3ca18e19" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_dd1cfa38-0086-49fa-8da8-4418a3a4a89c" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_fd322e01-d730-4a6d-b48d-4001dce51e53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_1a38eba7-4c1a-4b51-b698-f254f4da20a0" xlink:to="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_fd322e01-d730-4a6d-b48d-4001dce51e53" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_fd322e01-d730-4a6d-b48d-4001dce51e53_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_fd322e01-d730-4a6d-b48d-4001dce51e53" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_fd322e01-d730-4a6d-b48d-4001dce51e53_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanAssetCategoriesDomain_f7f3426d-8d61-4850-a467-fe24e9052f61" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanAssetCategoriesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DefinedBenefitPlanByPlanAssetCategoriesAxis_fd322e01-d730-4a6d-b48d-4001dce51e53" xlink:to="loc_us-gaap_PlanAssetCategoriesDomain_f7f3426d-8d61-4850-a467-fe24e9052f61" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanRealEstateMember_f307f166-6e3f-4411-b0fa-827427b580ab" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedBenefitPlanRealEstateMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_f7f3426d-8d61-4850-a467-fe24e9052f61" xlink:to="loc_us-gaap_DefinedBenefitPlanRealEstateMember_f307f166-6e3f-4411-b0fa-827427b580ab" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherDebtSecuritiesMember_25e39d67-c42a-45e6-b0e5-5cd77f37a444" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherDebtSecuritiesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_f7f3426d-8d61-4850-a467-fe24e9052f61" xlink:to="loc_us-gaap_OtherDebtSecuritiesMember_25e39d67-c42a-45e6-b0e5-5cd77f37a444" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_HedgeFundsAndOtherAssetsMember_cf049cbc-99a9-4b96-9f04-6d27c16a7e5d" xlink:href="ppg-20201231.xsd#ppg_HedgeFundsAndOtherAssetsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanAssetCategoriesDomain_f7f3426d-8d61-4850-a467-fe24e9052f61" xlink:to="loc_ppg_HedgeFundsAndOtherAssetsMember_cf049cbc-99a9-4b96-9f04-6d27c16a7e5d" xlink:type="arc" order="2"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/EmployeeBenefitPlansOtherPlansDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#EmployeeBenefitPlansOtherPlansDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/EmployeeBenefitPlansOtherPlansDetails" xlink:type="extended" id="i0df8cb0d36ba45bca6c3d33eada0a916_EmployeeBenefitPlansOtherPlansDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DefinedContributionPlanContributionRatesAsPercentageOfEmployeesEarnings_ccaa0e99-a3af-46fd-9078-29c96c9fa4d1" xlink:href="ppg-20201231.xsd#ppg_DefinedContributionPlanContributionRatesAsPercentageOfEmployeesEarnings"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_ppg_DefinedContributionPlanContributionRatesAsPercentageOfEmployeesEarnings_ccaa0e99-a3af-46fd-9078-29c96c9fa4d1" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedContributionPlanEmployerMatchingContributionPercentOfMatch_11498958-8906-4e43-b067-53bc2cd6bb2c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedContributionPlanEmployerMatchingContributionPercentOfMatch"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_us-gaap_DefinedContributionPlanEmployerMatchingContributionPercentOfMatch_11498958-8906-4e43-b067-53bc2cd6bb2c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOwnershipPlanESOPCompensationExpense_ca0bda72-a9cf-480a-a879-95f1cc1f46c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOwnershipPlanESOPCompensationExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_us-gaap_EmployeeStockOwnershipPlanESOPCompensationExpense_ca0bda72-a9cf-480a-a879-95f1cc1f46c8" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOwnershipPlanESOPDividendsPaidToESOP_56533817-9bf5-4aa1-8632-cd4662bd9eb1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOwnershipPlanESOPDividendsPaidToESOP"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_us-gaap_EmployeeStockOwnershipPlanESOPDividendsPaidToESOP_56533817-9bf5-4aa1-8632-cd4662bd9eb1" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedContributionPlanCostRecognized_86f31bbc-3942-4cfa-b61b-d5051025866e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedContributionPlanCostRecognized"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_us-gaap_DefinedContributionPlanCostRecognized_86f31bbc-3942-4cfa-b61b-d5051025866e" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DeferredCompensationArrangementWithIndividualCompensationExpenseIncome_6140f21a-238d-491f-8876-6708ff9ea7e0" xlink:href="ppg-20201231.xsd#ppg_DeferredCompensationArrangementWithIndividualCompensationExpenseIncome"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_ppg_DeferredCompensationArrangementWithIndividualCompensationExpenseIncome_6140f21a-238d-491f-8876-6708ff9ea7e0" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DeferredCompensationArrangementWithIndividualIncreaseDecreaseInFairValueOfInvestments_fba4d514-1776-4105-a677-6377d8332180" xlink:href="ppg-20201231.xsd#ppg_DeferredCompensationArrangementWithIndividualIncreaseDecreaseInFairValueOfInvestments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_ppg_DeferredCompensationArrangementWithIndividualIncreaseDecreaseInFairValueOfInvestments_fba4d514-1776-4105-a677-6377d8332180" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationArrangementWithIndividualRecordedLiability_86d8cef7-6c79-4c4b-acaa-d748be60c429" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredCompensationArrangementWithIndividualRecordedLiability"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_us-gaap_DeferredCompensationArrangementWithIndividualRecordedLiability_86d8cef7-6c79-4c4b-acaa-d748be60c429" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_DeferredCompensationPlanMarketableSecurities_2e8299e6-8b78-4f19-addd-f338a2a93d53" xlink:href="ppg-20201231.xsd#ppg_DeferredCompensationPlanMarketableSecurities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_ppg_DeferredCompensationPlanMarketableSecurities_2e8299e6-8b78-4f19-addd-f338a2a93d53" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_af8adbd9-af7b-46cc-8fe8-c2d32cbe8625" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_1bda45da-8d9e-466a-a1a2-14851bf160f9" xlink:to="loc_us-gaap_StatementTable_af8adbd9-af7b-46cc-8fe8-c2d32cbe8625" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_6c99566e-5aac-41dd-81c9-72eec0b65d56" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_af8adbd9-af7b-46cc-8fe8-c2d32cbe8625" xlink:to="loc_srt_RangeAxis_6c99566e-5aac-41dd-81c9-72eec0b65d56" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_6c99566e-5aac-41dd-81c9-72eec0b65d56_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_6c99566e-5aac-41dd-81c9-72eec0b65d56" xlink:to="loc_srt_RangeMember_6c99566e-5aac-41dd-81c9-72eec0b65d56_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_c883fb45-da48-4b26-84b1-8fef9ab301db" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_6c99566e-5aac-41dd-81c9-72eec0b65d56" xlink:to="loc_srt_RangeMember_c883fb45-da48-4b26-84b1-8fef9ab301db" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/CommitmentsandContingentLiabilities" xlink:type="simple" xlink:href="ppg-20201231.xsd#CommitmentsandContingentLiabilities"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CommitmentsandContingentLiabilities" xlink:type="extended" id="i70af17ec171f44c9886c02b40bea16bb_CommitmentsandContingentLiabilities"/>
<link:roleRef roleURI="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#CommitmentsandContingentLiabilitiesTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesTables" xlink:type="extended" id="i08907292a48b4157bb525b7cc359462d_CommitmentsandContingentLiabilitiesTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesShareholderClassActionDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#CommitmentsandContingentLiabilitiesShareholderClassActionDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesShareholderClassActionDetails" xlink:type="extended" id="i09c1ca0a21f54484a6d9720a38e10a2b_CommitmentsandContingentLiabilitiesShareholderClassActionDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesLitigationSettlementsAsbestosMattersandOtherDisclosureDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#CommitmentsandContingentLiabilitiesLitigationSettlementsAsbestosMattersandOtherDisclosureDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesLitigationSettlementsAsbestosMattersandOtherDisclosureDetail" xlink:type="extended" id="ic82fb09a382c4202acf77c3f906d5c33_CommitmentsandContingentLiabilitiesLitigationSettlementsAsbestosMattersandOtherDisclosureDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_a2c80aa7-88c7-4bff-b45f-5cfe7d09f96d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_0fb7a12f-7fcf-4fd9-834c-cbfa0777d9e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_a2c80aa7-88c7-4bff-b45f-5cfe7d09f96d" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_0fb7a12f-7fcf-4fd9-834c-cbfa0777d9e1" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_29407c99-a335-4327-bc67-5475629f82d9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_a2c80aa7-88c7-4bff-b45f-5cfe7d09f96d" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_29407c99-a335-4327-bc67-5475629f82d9" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_OtherReserves_e699df1f-f5e0-4a2c-966e-75494e8285d9" xlink:href="ppg-20201231.xsd#ppg_OtherReserves"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_a2c80aa7-88c7-4bff-b45f-5cfe7d09f96d" xlink:to="loc_ppg_OtherReserves_e699df1f-f5e0-4a2c-966e-75494e8285d9" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilityForAsbestosAndEnvironmentalClaimsGrossPeriodIncreaseDecrease_89d85a8e-2778-43bb-a377-7144d20e8df4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilityForAsbestosAndEnvironmentalClaimsGrossPeriodIncreaseDecrease"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_a2c80aa7-88c7-4bff-b45f-5cfe7d09f96d" xlink:to="loc_us-gaap_LiabilityForAsbestosAndEnvironmentalClaimsGrossPeriodIncreaseDecrease_89d85a8e-2778-43bb-a377-7144d20e8df4" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_5f206ff3-6f64-4041-b247-b8813c908c2d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_a2c80aa7-88c7-4bff-b45f-5cfe7d09f96d" xlink:to="loc_us-gaap_StatementTable_5f206ff3-6f64-4041-b247-b8813c908c2d" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_1c93ef07-c9bb-45eb-bde4-d81c155420f3" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_5f206ff3-6f64-4041-b247-b8813c908c2d" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_1c93ef07-c9bb-45eb-bde4-d81c155420f3" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_1c93ef07-c9bb-45eb-bde4-d81c155420f3_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_EquityMethodInvesteeNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_1c93ef07-c9bb-45eb-bde4-d81c155420f3" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_1c93ef07-c9bb-45eb-bde4-d81c155420f3_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_504af86e-9bb3-43dd-b827-1c7be1967ff8" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_EquityMethodInvesteeNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_1c93ef07-c9bb-45eb-bde4-d81c155420f3" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_504af86e-9bb3-43dd-b827-1c7be1967ff8" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PittsburghCorningCorporationMember_68aee1c3-c90b-43ab-aa6d-a13f8f0ed522" xlink:href="ppg-20201231.xsd#ppg_PittsburghCorningCorporationMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_504af86e-9bb3-43dd-b827-1c7be1967ff8" xlink:to="loc_ppg_PittsburghCorningCorporationMember_68aee1c3-c90b-43ab-aa6d-a13f8f0ed522" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_e150bec9-371b-4b4f-b990-c5490cbd6403" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_5f206ff3-6f64-4041-b247-b8813c908c2d" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_e150bec9-371b-4b4f-b990-c5490cbd6403" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_e150bec9-371b-4b4f-b990-c5490cbd6403_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_e150bec9-371b-4b4f-b990-c5490cbd6403" xlink:to="loc_us-gaap_LossContingencyNatureDomain_e150bec9-371b-4b4f-b990-c5490cbd6403_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_90461ad0-bde8-4ed5-b13d-7d8fe100f309" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LossContingencyNatureDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_e150bec9-371b-4b4f-b990-c5490cbd6403" xlink:to="loc_us-gaap_LossContingencyNatureDomain_90461ad0-bde8-4ed5-b13d-7d8fe100f309" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AsbestosIssueMember_cfd9ea2a-c0b6-49ab-a119-7f691316e70b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AsbestosIssueMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyNatureDomain_90461ad0-bde8-4ed5-b13d-7d8fe100f309" xlink:to="loc_us-gaap_AsbestosIssueMember_cfd9ea2a-c0b6-49ab-a119-7f691316e70b" xlink:type="arc" order="0"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesAdditionalInformationEnvironmentalMattersDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#CommitmentsandContingentLiabilitiesAdditionalInformationEnvironmentalMattersDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/CommitmentsandContingentLiabilitiesAdditionalInformationEnvironmentalMattersDetail" xlink:type="extended" id="i771e33a52c234b6d8a6c3217eb2ce47a_CommitmentsandContingentLiabilitiesAdditionalInformationEnvironmentalMattersDetail">
<link:loc xlink:type="locator" xlink:label="loc_ppg_CommitmentsAndContingenciesDisclosureLineItems_ed2acbc4-db40-4d16-92da-89ca672b2300" xlink:href="ppg-20201231.xsd#ppg_CommitmentsAndContingenciesDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:href="ppg-20201231.xsd#ppg_EnvironmentalMattersAbstract"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_CommitmentsAndContingenciesDisclosureLineItems_ed2acbc4-db40-4d16-92da-89ca672b2300" xlink:to="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingencies_98001034-19b9-4f04-8264-46d7df6e9904" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingencies"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingencies_98001034-19b9-4f04-8264-46d7df6e9904" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedEnvironmentalLossContingenciesCurrent_972158e7-d614-4c01-a5f4-09b8647def99" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedEnvironmentalLossContingenciesCurrent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_us-gaap_AccruedEnvironmentalLossContingenciesCurrent_972158e7-d614-4c01-a5f4-09b8647def99" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EnvironmentalRemediationExpense_72e64c08-0d22-4111-bc22-c4505fc7cbc0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EnvironmentalRemediationExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_us-gaap_EnvironmentalRemediationExpense_72e64c08-0d22-4111-bc22-c4505fc7cbc0" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForEnvironmentalLiabilities_a6cefc8d-8165-437f-a2a6-5a42e36c919c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForEnvironmentalLiabilities"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_us-gaap_PaymentsForEnvironmentalLiabilities_a6cefc8d-8165-437f-a2a6-5a42e36c919c" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_HistoricalEnvironmentalRemediationExpenseLowerLimit_4ca4bd8f-2151-415d-a445-ef3a8aceef67" xlink:href="ppg-20201231.xsd#ppg_HistoricalEnvironmentalRemediationExpenseLowerLimit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_ppg_HistoricalEnvironmentalRemediationExpenseLowerLimit_4ca4bd8f-2151-415d-a445-ef3a8aceef67" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_HistoricalEnvironmentalRemediationExpenseUpperLimit_038ffb96-1e2e-4c4f-a7de-9f612f5e1985" xlink:href="ppg-20201231.xsd#ppg_HistoricalEnvironmentalRemediationExpenseUpperLimit"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_ppg_HistoricalEnvironmentalRemediationExpenseUpperLimit_038ffb96-1e2e-4c4f-a7de-9f612f5e1985" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_RemediationPeriod_bde76b57-4da4-4b54-aefd-c612d58665c8" xlink:href="ppg-20201231.xsd#ppg_RemediationPeriod"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_ppg_RemediationPeriod_bde76b57-4da4-4b54-aefd-c612d58665c8" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_CashForEnvironmentalLossContingenciesLowEstimate_4a434c91-307e-4f43-a0c8-455d271993b1" xlink:href="ppg-20201231.xsd#ppg_CashForEnvironmentalLossContingenciesLowEstimate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_ppg_CashForEnvironmentalLossContingenciesLowEstimate_4a434c91-307e-4f43-a0c8-455d271993b1" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_CashForEnvironmentalLossContingenciesHighEstimate_569c081c-8067-4b57-876b-52b9dc78c5a8" xlink:href="ppg-20201231.xsd#ppg_CashForEnvironmentalLossContingenciesHighEstimate"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_ppg_CashForEnvironmentalLossContingenciesHighEstimate_569c081c-8067-4b57-876b-52b9dc78c5a8" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NumberOfSitesInvolvedForEnvironmentalRemediation_53844cbf-22bf-473c-8733-cd33b110da24" xlink:href="ppg-20201231.xsd#ppg_NumberOfSitesInvolvedForEnvironmentalRemediation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_ppg_NumberOfSitesInvolvedForEnvironmentalRemediation_53844cbf-22bf-473c-8733-cd33b110da24" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PercentageOfTotalRemainingReserve_b06f4ab9-bca6-49a6-9497-8e912d6dcd95" xlink:href="ppg-20201231.xsd#ppg_PercentageOfTotalRemainingReserve"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_ppg_PercentageOfTotalRemainingReserve_b06f4ab9-bca6-49a6-9497-8e912d6dcd95" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EnvironmentalExitCostsReasonablyPossibleAdditionalLoss_1f5db0e4-2ae5-4ede-85c0-be8d0f06feba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EnvironmentalExitCostsReasonablyPossibleAdditionalLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_EnvironmentalMattersAbstract_0bac7ba3-94da-4ded-a827-a16a3eb3c6e1" xlink:to="loc_us-gaap_EnvironmentalExitCostsReasonablyPossibleAdditionalLoss_1f5db0e4-2ae5-4ede-85c0-be8d0f06feba" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_CommitmentsAndContingenciesDisclosureTable_d70f5d38-1c7b-4795-b566-ace9b359a8fc" xlink:href="ppg-20201231.xsd#ppg_CommitmentsAndContingenciesDisclosureTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_ppg_CommitmentsAndContingenciesDisclosureLineItems_ed2acbc4-db40-4d16-92da-89ca672b2300" xlink:to="loc_ppg_CommitmentsAndContingenciesDisclosureTable_d70f5d38-1c7b-4795-b566-ace9b359a8fc" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EnvironmentalRemediationSiteAxis_194eada0-348f-45a8-ab63-a94065456f16" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EnvironmentalRemediationSiteAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_CommitmentsAndContingenciesDisclosureTable_d70f5d38-1c7b-4795-b566-ace9b359a8fc" xlink:to="loc_us-gaap_EnvironmentalRemediationSiteAxis_194eada0-348f-45a8-ab63-a94065456f16" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EnvironmentalRemediationSiteDomain_194eada0-348f-45a8-ab63-a94065456f16_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EnvironmentalRemediationSiteDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteAxis_194eada0-348f-45a8-ab63-a94065456f16" xlink:to="loc_us-gaap_EnvironmentalRemediationSiteDomain_194eada0-348f-45a8-ab63-a94065456f16_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EnvironmentalRemediationSiteDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteAxis_194eada0-348f-45a8-ab63-a94065456f16" xlink:to="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ExcavationofSoilMemberMember_92b3e6ae-11d2-4bd4-be8e-f48077884427" xlink:href="ppg-20201231.xsd#ppg_ExcavationofSoilMemberMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:to="loc_ppg_ExcavationofSoilMemberMember_92b3e6ae-11d2-4bd4-be8e-f48077884427" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_SoilTreatmentTransportationAndDisposalOfExcavatedSoilMember_45b1302a-e8df-49ae-9b7b-92a3d7f448e7" xlink:href="ppg-20201231.xsd#ppg_SoilTreatmentTransportationAndDisposalOfExcavatedSoilMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:to="loc_ppg_SoilTreatmentTransportationAndDisposalOfExcavatedSoilMember_45b1302a-e8df-49ae-9b7b-92a3d7f448e7" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ConstructionServicesMember_1461d791-1782-41e5-9c34-4dfdfb3bdc15" xlink:href="ppg-20201231.xsd#ppg_ConstructionServicesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:to="loc_ppg_ConstructionServicesMember_1461d791-1782-41e5-9c34-4dfdfb3bdc15" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_JerseyCityManufacturingPlantMember_86ea21a2-db73-4fc5-9fc3-0b33484de5c8" xlink:href="ppg-20201231.xsd#ppg_JerseyCityManufacturingPlantMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:to="loc_ppg_JerseyCityManufacturingPlantMember_86ea21a2-db73-4fc5-9fc3-0b33484de5c8" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_LegacyGlassandChemicalSitesMember_d38555ad-d5b6-4862-a6c9-44f5e46251de" xlink:href="ppg-20201231.xsd#ppg_LegacyGlassandChemicalSitesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:to="loc_ppg_LegacyGlassandChemicalSitesMember_d38555ad-d5b6-4862-a6c9-44f5e46251de" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_OtherEnvironmentalContingenciesMember_848a052b-ffbe-466f-8c1c-e52db83203bd" xlink:href="ppg-20201231.xsd#ppg_OtherEnvironmentalContingenciesMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:to="loc_ppg_OtherEnvironmentalContingenciesMember_848a052b-ffbe-466f-8c1c-e52db83203bd" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_JudicialConsentOrderMember_48729fba-7fc2-4452-b678-bd62e1d7ba37" xlink:href="ppg-20201231.xsd#ppg_JudicialConsentOrderMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EnvironmentalRemediationSiteDomain_f12a86fe-57bd-4375-bf87-ed8882e24e6d" xlink:to="loc_ppg_JudicialConsentOrderMember_48729fba-7fc2-4452-b678-bd62e1d7ba37" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_dd65e62c-d5b6-4a38-98da-3a1bc295127a" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementScenarioAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_CommitmentsAndContingenciesDisclosureTable_d70f5d38-1c7b-4795-b566-ace9b359a8fc" xlink:to="loc_srt_StatementScenarioAxis_dd65e62c-d5b6-4a38-98da-3a1bc295127a" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_dd65e62c-d5b6-4a38-98da-3a1bc295127a_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementScenarioAxis_dd65e62c-d5b6-4a38-98da-3a1bc295127a" xlink:to="loc_srt_ScenarioUnspecifiedDomain_dd65e62c-d5b6-4a38-98da-3a1bc295127a_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_434b8a22-3a17-49b4-a1d2-45bfa670a8a3" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioUnspecifiedDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementScenarioAxis_dd65e62c-d5b6-4a38-98da-3a1bc295127a" xlink:to="loc_srt_ScenarioUnspecifiedDomain_434b8a22-3a17-49b4-a1d2-45bfa670a8a3" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_16fda0fd-bb64-44ba-9566-d3776c754879" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ScenarioForecastMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ScenarioUnspecifiedDomain_434b8a22-3a17-49b4-a1d2-45bfa670a8a3" xlink:to="loc_srt_ScenarioForecastMember_16fda0fd-bb64-44ba-9566-d3776c754879" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_4c4a130f-8135-406f-a8bf-902769f7427c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_CommitmentsAndContingenciesDisclosureTable_d70f5d38-1c7b-4795-b566-ace9b359a8fc" xlink:to="loc_srt_RangeAxis_4c4a130f-8135-406f-a8bf-902769f7427c" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_4c4a130f-8135-406f-a8bf-902769f7427c_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_4c4a130f-8135-406f-a8bf-902769f7427c" xlink:to="loc_srt_RangeMember_4c4a130f-8135-406f-a8bf-902769f7427c_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_3d02ad48-7854-45fb-9f74-56988a6c171f" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_4c4a130f-8135-406f-a8bf-902769f7427c" xlink:to="loc_srt_RangeMember_3d02ad48-7854-45fb-9f74-56988a6c171f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_cbd0bda1-604a-4470-967a-d4a716694bad" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_3d02ad48-7854-45fb-9f74-56988a6c171f" xlink:to="loc_srt_MaximumMember_cbd0bda1-604a-4470-967a-d4a716694bad" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_9cdc8824-d954-4cbd-ab23-3d26bc865faa" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_3d02ad48-7854-45fb-9f74-56988a6c171f" xlink:to="loc_srt_MinimumMember_9cdc8824-d954-4cbd-ab23-3d26bc865faa" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/ShareholdersEquity" xlink:type="simple" xlink:href="ppg-20201231.xsd#ShareholdersEquity"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ShareholdersEquity" xlink:type="extended" id="i6e393abfbb174fca90535ab1c3c18dbb_ShareholdersEquity"/>
<link:roleRef roleURI="http://www.ppg.com/role/ShareholdersEquityTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#ShareholdersEquityTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ShareholdersEquityTables" xlink:type="extended" id="i11705a55f9bd4fc8bcdf40b242357ec3_ShareholdersEquityTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/ShareholdersEquitySummaryofSharesOutstandingDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#ShareholdersEquitySummaryofSharesOutstandingDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ShareholdersEquitySummaryofSharesOutstandingDetail" xlink:type="extended" id="i0f581a81021643fbb6b27fd3cedf4934_ShareholdersEquitySummaryofSharesOutstandingDetail">
<link:loc xlink:type="locator" xlink:label="loc_ppg_ShareholdersEquityNoteLineItems_729e41d4-1c4d-40c5-82a8-a27763600303" xlink:href="ppg-20201231.xsd#ppg_ShareholdersEquityNoteLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_0b252491-c110-4f75-9d9d-55357278b669" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ShareholdersEquityNoteLineItems_729e41d4-1c4d-40c5-82a8-a27763600303" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_0b252491-c110-4f75-9d9d-55357278b669" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockNoParValue_b6022cfe-a926-4e61-9257-24b8c2f89477" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockNoParValue"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ShareholdersEquityNoteLineItems_729e41d4-1c4d-40c5-82a8-a27763600303" xlink:to="loc_us-gaap_PreferredStockNoParValue_b6022cfe-a926-4e61-9257-24b8c2f89477" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_dc2643a3-7570-4396-b502-b5cde94d4baf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ShareholdersEquityNoteLineItems_729e41d4-1c4d-40c5-82a8-a27763600303" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_dc2643a3-7570-4396-b502-b5cde94d4baf" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockDividendsPerShareCashPaid_ecf266dc-9d9b-449d-bb4d-4eb1db027f66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockDividendsPerShareCashPaid"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ShareholdersEquityNoteLineItems_729e41d4-1c4d-40c5-82a8-a27763600303" xlink:to="loc_us-gaap_CommonStockDividendsPerShareCashPaid_ecf266dc-9d9b-449d-bb4d-4eb1db027f66" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_eca8e95d-6ae9-44cb-af3a-81b0afe939c0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ShareholdersEquityNoteLineItems_729e41d4-1c4d-40c5-82a8-a27763600303" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_eca8e95d-6ae9-44cb-af3a-81b0afe939c0" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_75d1bfbf-2851-4a4b-925a-7f90b72fb272" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_eca8e95d-6ae9-44cb-af3a-81b0afe939c0" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_75d1bfbf-2851-4a4b-925a-7f90b72fb272" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchasedDuringPeriodShares_56d064a1-514d-4815-9d58-130037b18c9b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockRepurchasedDuringPeriodShares"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_eca8e95d-6ae9-44cb-af3a-81b0afe939c0" xlink:to="loc_us-gaap_StockRepurchasedDuringPeriodShares_56d064a1-514d-4815-9d58-130037b18c9b" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesTreasuryStockReissued_98074b66-fdf1-47ad-94e4-bb9da968a7b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesTreasuryStockReissued"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_eca8e95d-6ae9-44cb-af3a-81b0afe939c0" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesTreasuryStockReissued_98074b66-fdf1-47ad-94e4-bb9da968a7b4" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_0f55dbf2-cf47-450f-bfcb-717de91561ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ShareholdersEquityNoteTable_74c6bf04-39d8-4cd8-a9f2-9ba2ccac6798" xlink:href="ppg-20201231.xsd#ppg_ShareholdersEquityNoteTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_ppg_ShareholdersEquityNoteLineItems_729e41d4-1c4d-40c5-82a8-a27763600303" xlink:to="loc_ppg_ShareholdersEquityNoteTable_74c6bf04-39d8-4cd8-a9f2-9ba2ccac6798" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_dcfd00d5-a70c-4fe2-994b-8f0a9a229d7c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ppg_ShareholdersEquityNoteTable_74c6bf04-39d8-4cd8-a9f2-9ba2ccac6798" xlink:to="loc_us-gaap_StatementClassOfStockAxis_dcfd00d5-a70c-4fe2-994b-8f0a9a229d7c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_dcfd00d5-a70c-4fe2-994b-8f0a9a229d7c_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementClassOfStockAxis_dcfd00d5-a70c-4fe2-994b-8f0a9a229d7c" xlink:to="loc_us-gaap_ClassOfStockDomain_dcfd00d5-a70c-4fe2-994b-8f0a9a229d7c_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_33e2fc8e-47bd-481c-951a-149a2b788f8a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementClassOfStockAxis_dcfd00d5-a70c-4fe2-994b-8f0a9a229d7c" xlink:to="loc_us-gaap_ClassOfStockDomain_33e2fc8e-47bd-481c-951a-149a2b788f8a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_51363fbf-8092-4981-b496-ff9fb9432f65" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_33e2fc8e-47bd-481c-951a-149a2b788f8a" xlink:to="loc_us-gaap_CommonStockMember_51363fbf-8092-4981-b496-ff9fb9432f65" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockMember_86324c32-b000-42a0-9346-f2ca2b00a95a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TreasuryStockMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_33e2fc8e-47bd-481c-951a-149a2b788f8a" xlink:to="loc_us-gaap_TreasuryStockMember_86324c32-b000-42a0-9346-f2ca2b00a95a" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/AccumulatedOtherComprehensiveLoss" xlink:type="simple" xlink:href="ppg-20201231.xsd#AccumulatedOtherComprehensiveLoss"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AccumulatedOtherComprehensiveLoss" xlink:type="extended" id="i5afd9f0c62ab43fba7eb662b8e1c6ae7_AccumulatedOtherComprehensiveLoss"/>
<link:roleRef roleURI="http://www.ppg.com/role/AccumulatedOtherComprehensiveLossTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#AccumulatedOtherComprehensiveLossTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AccumulatedOtherComprehensiveLossTables" xlink:type="extended" id="i30e70284f41543798c982d57af315c9b_AccumulatedOtherComprehensiveLossTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/AccumulatedOtherComprehensiveLossDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#AccumulatedOtherComprehensiveLossDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AccumulatedOtherComprehensiveLossDetail" xlink:type="extended" id="i95cb06c1522a48eb80e8ad26d863c44c_AccumulatedOtherComprehensiveLossDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_d0949878-0310-4444-8d61-817695d74625" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_d0949878-0310-4444-8d61-817695d74625" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ff1d8ac3-66ef-4255-92e0-098fc595172c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ff1d8ac3-66ef-4255-92e0-098fc595172c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax_e90949aa-d150-441b-a3ba-ae9bc37de721" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax_e90949aa-d150-441b-a3ba-ae9bc37de721" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_a700bbff-e9c6-4ef0-9281-f8f27be3dd64" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_a700bbff-e9c6-4ef0-9281-f8f27be3dd64" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentTax_fa65f949-95a8-458c-802e-6e0d30f8ddd5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentTax_fa65f949-95a8-458c-802e-6e0d30f8ddd5" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_d4a23ec0-e42b-47c8-a04e-3a55c4798f9c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_d4a23ec0-e42b-47c8-a04e-3a55c4798f9c" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationsOfTemporaryToPermanentEquity_31330847-1793-4f8a-92fd-e485378823c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReclassificationsOfTemporaryToPermanentEquity"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_ReclassificationsOfTemporaryToPermanentEquity_31330847-1793-4f8a-92fd-e485378823c8" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_56f1229f-08c9-4160-88d0-d80ec4f5c73b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_56f1229f-08c9-4160-88d0-d80ec4f5c73b" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_523660b5-c909-470f-83a8-06fbbc91e82f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_523660b5-c909-470f-83a8-06fbbc91e82f" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_b2e2a5df-ed50-42ee-ac4c-b64369e4ddb7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b103a8ac-c4d1-4159-b887-5f16a7c0706f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_1ed21257-f303-4e2b-9ee9-1d2dc399f49f" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b103a8ac-c4d1-4159-b887-5f16a7c0706f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_cf66516b-07b9-41e3-a592-26369ec6595a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_b103a8ac-c4d1-4159-b887-5f16a7c0706f" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_cf66516b-07b9-41e3-a592-26369ec6595a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_cf66516b-07b9-41e3-a592-26369ec6595a_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_cf66516b-07b9-41e3-a592-26369ec6595a" xlink:to="loc_us-gaap_EquityComponentDomain_cf66516b-07b9-41e3-a592-26369ec6595a_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_cf66516b-07b9-41e3-a592-26369ec6595a" xlink:to="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_4d6eb717-44f3-4f2f-b54b-e9b57af711cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_4d6eb717-44f3-4f2f-b54b-e9b57af711cf" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_fec0bd3a-f0cb-48ac-a555-4857d75bdfb1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:to="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_fec0bd3a-f0cb-48ac-a555-4857d75bdfb1" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossCashFlowHedgeIncludingNoncontrollingInterestMember_fa38607f-39b3-45ac-a02f-59bd14e2c58c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedGainLossCashFlowHedgeIncludingNoncontrollingInterestMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:to="loc_us-gaap_AccumulatedGainLossCashFlowHedgeIncludingNoncontrollingInterestMember_fa38607f-39b3-45ac-a02f-59bd14e2c58c" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_80e1159a-0c91-482a-8f8b-f59d64b06dc3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_80e1159a-0c91-482a-8f8b-f59d64b06dc3" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_ffa62231-9ae0-4e7d-b604-0d7fd7b4d14c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_ffa62231-9ae0-4e7d-b604-0d7fd7b4d14c" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ParentMember_9c48c96f-18d9-4bd4-87ad-e4c38d61324a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ParentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_84125505-0859-423a-b93e-9bbb08e4dd53" xlink:to="loc_us-gaap_ParentMember_9c48c96f-18d9-4bd4-87ad-e4c38d61324a" xlink:type="arc" order="5"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/AccumulatedOtherComprehensiveLossAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#AccumulatedOtherComprehensiveLossAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/AccumulatedOtherComprehensiveLossAdditionalInformationDetail" xlink:type="extended" id="id8f0b12d710b43118a386c84e1d2b14b_AccumulatedOtherComprehensiveLossAdditionalInformationDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/OtherIncome" xlink:type="simple" xlink:href="ppg-20201231.xsd#OtherIncome"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/OtherIncome" xlink:type="extended" id="ie94051e73f44441f8e6b252c02a5c629_OtherIncome"/>
<link:roleRef roleURI="http://www.ppg.com/role/OtherIncomeTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#OtherIncomeTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/OtherIncomeTables" xlink:type="extended" id="i6fe22034c9c347cebe385e61e482578a_OtherIncomeTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/OtherIncomeDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#OtherIncomeDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/OtherIncomeDetail" xlink:type="extended" id="i999bcd6051eb4ae996e98b5d8f405a88_OtherIncomeDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/StockBasedCompensation" xlink:type="simple" xlink:href="ppg-20201231.xsd#StockBasedCompensation"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/StockBasedCompensation" xlink:type="extended" id="ib0d6e01bff87458690314f557f1f4dcb_StockBasedCompensation"/>
<link:roleRef roleURI="http://www.ppg.com/role/StockBasedCompensationTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#StockBasedCompensationTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/StockBasedCompensationTables" xlink:type="extended" id="iec842579a3a8449188a035cb1b9fb00b_StockBasedCompensationTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/StockBasedCompensationAdditionalInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#StockBasedCompensationAdditionalInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/StockBasedCompensationAdditionalInformationDetail" xlink:type="extended" id="if57f4e216d6349129ad915eb7a35e73b_StockBasedCompensationAdditionalInformationDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_8e7ebb33-9203-4373-838c-29f402af8472" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_8e7ebb33-9203-4373-838c-29f402af8472" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_f669b819-31a5-4902-8ce2-980fc6679060" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_f669b819-31a5-4902-8ce2-980fc6679060" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationDescriptionAndTerms_1170b00a-471e-4a73-872f-fa5b70c7164d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationDescriptionAndTerms"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationDescriptionAndTerms_1170b00a-471e-4a73-872f-fa5b70c7164d" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_3db0cd6b-c7c1-4d7f-9e5d-d4c653f51652" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_3db0cd6b-c7c1-4d7f-9e5d-d4c653f51652" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_353b63d7-5752-4381-9a8b-820c0d816ae7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensation"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_ShareBasedCompensation_353b63d7-5752-4381-9a8b-820c0d816ae7" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxExpenseFromStockOptionsExercised_b2465a71-95f0-4aab-94a0-b3eeb667b591" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxExpenseFromStockOptionsExercised"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_DeferredTaxExpenseFromStockOptionsExercised_b2465a71-95f0-4aab-94a0-b3eeb667b591" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_a6ee6658-314b-440e-9bc8-91ac7ef5c299" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_a6ee6658-314b-440e-9bc8-91ac7ef5c299" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_75f4fd32-f47d-4c9a-a5a3-16a6b61375da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_75f4fd32-f47d-4c9a-a5a3-16a6b61375da" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_95ed4ac3-4a10-4528-8a31-bb16173715b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_95ed4ac3-4a10-4528-8a31-bb16173715b0" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ShareBasedCompensationArrangementByShareBasedPaymentAwardTargetAward_f93c1d23-5bf9-4311-aa80-e8210ba1f650" xlink:href="ppg-20201231.xsd#ppg_ShareBasedCompensationArrangementByShareBasedPaymentAwardTargetAward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_ppg_ShareBasedCompensationArrangementByShareBasedPaymentAwardTargetAward_f93c1d23-5bf9-4311-aa80-e8210ba1f650" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPercentage_7c27e12f-2573-4aaf-8c1d-5f7ff39c3eb9" xlink:href="ppg-20201231.xsd#ppg_ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPercentage"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_ppg_ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPercentage_7c27e12f-2573-4aaf-8c1d-5f7ff39c3eb9" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PerformanceSharePayout_ad32badb-2129-418c-b1f3-030b87e052a5" xlink:href="ppg-20201231.xsd#ppg_PerformanceSharePayout"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_ppg_PerformanceSharePayout_ad32badb-2129-418c-b1f3-030b87e052a5" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NumberOfPerformanceTargetsMet_905aa85e-6e14-4973-8e55-31f23ec78567" xlink:href="ppg-20201231.xsd#ppg_NumberOfPerformanceTargetsMet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_ppg_NumberOfPerformanceTargetsMet_905aa85e-6e14-4973-8e55-31f23ec78567" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_NumberOfPerformanceTargets_9553b966-f3d7-4784-891f-dc81b751170d" xlink:href="ppg-20201231.xsd#ppg_NumberOfPerformanceTargets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_ppg_NumberOfPerformanceTargets_9553b966-f3d7-4784-891f-dc81b751170d" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ee43af6-71b1-4686-91e5-f21ac6a620cd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_fd2c672a-6a7c-45b9-a061-4f5061f086be" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ee43af6-71b1-4686-91e5-f21ac6a620cd" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_a5752b94-7044-4112-a09d-61c5f2ab617d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ee43af6-71b1-4686-91e5-f21ac6a620cd" xlink:to="loc_us-gaap_AwardTypeAxis_a5752b94-7044-4112-a09d-61c5f2ab617d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_a5752b94-7044-4112-a09d-61c5f2ab617d_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_a5752b94-7044-4112-a09d-61c5f2ab617d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_a5752b94-7044-4112-a09d-61c5f2ab617d_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6a351d7e-58c0-40c3-9ee1-243c98ff1173" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_a5752b94-7044-4112-a09d-61c5f2ab617d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6a351d7e-58c0-40c3-9ee1-243c98ff1173" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_5a99332f-37d0-4d70-88e1-6289f5a52b31" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6a351d7e-58c0-40c3-9ee1-243c98ff1173" xlink:to="loc_us-gaap_EmployeeStockOptionMember_5a99332f-37d0-4d70-88e1-6289f5a52b31" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_cc19e4c4-0fe7-404a-a68b-739ca5f42feb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6a351d7e-58c0-40c3-9ee1-243c98ff1173" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_cc19e4c4-0fe7-404a-a68b-739ca5f42feb" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockCompensationPlanMember_59199d42-c348-425d-8885-86cf06e3af48" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockCompensationPlanMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6a351d7e-58c0-40c3-9ee1-243c98ff1173" xlink:to="loc_us-gaap_StockCompensationPlanMember_59199d42-c348-425d-8885-86cf06e3af48" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOwnershipPlanESOPDisclosuresByPlanAxis_ea199294-7217-48c0-b44c-dc5257bc3da2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOwnershipPlanESOPDisclosuresByPlanAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ee43af6-71b1-4686-91e5-f21ac6a620cd" xlink:to="loc_us-gaap_EmployeeStockOwnershipPlanESOPDisclosuresByPlanAxis_ea199294-7217-48c0-b44c-dc5257bc3da2" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain_ea199294-7217-48c0-b44c-dc5257bc3da2_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_EmployeeStockOwnershipPlanESOPDisclosuresByPlanAxis_ea199294-7217-48c0-b44c-dc5257bc3da2" xlink:to="loc_us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain_ea199294-7217-48c0-b44c-dc5257bc3da2_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain_79a0715d-a8e2-4c0d-b27e-c2a232cb4061" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_EmployeeStockOwnershipPlanESOPDisclosuresByPlanAxis_ea199294-7217-48c0-b44c-dc5257bc3da2" xlink:to="loc_us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain_79a0715d-a8e2-4c0d-b27e-c2a232cb4061" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PerformancePeriod2017to2019DomainDomain_7e2bcef2-2eca-48c1-a91b-ff11847a6cef" xlink:href="ppg-20201231.xsd#ppg_PerformancePeriod2017to2019DomainDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain_79a0715d-a8e2-4c0d-b27e-c2a232cb4061" xlink:to="loc_ppg_PerformancePeriod2017to2019DomainDomain_7e2bcef2-2eca-48c1-a91b-ff11847a6cef" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PerformancePeriod2018to2020DomainDomain_d957740a-b4ec-4c92-bc53-b5023e9dc3d9" xlink:href="ppg-20201231.xsd#ppg_PerformancePeriod2018to2020DomainDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain_79a0715d-a8e2-4c0d-b27e-c2a232cb4061" xlink:to="loc_ppg_PerformancePeriod2018to2020DomainDomain_d957740a-b4ec-4c92-bc53-b5023e9dc3d9" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PerformancePeriod2019to2021Domain_5935f982-2155-42bb-ad6e-1c4cc79b3e49" xlink:href="ppg-20201231.xsd#ppg_PerformancePeriod2019to2021Domain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EmployeeStockOwnershipPlanESOPPlanDomain_79a0715d-a8e2-4c0d-b27e-c2a232cb4061" xlink:to="loc_ppg_PerformancePeriod2019to2021Domain_5935f982-2155-42bb-ad6e-1c4cc79b3e49" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_2d248fe1-5025-4214-b9fa-e6c4eb94d61c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0ee43af6-71b1-4686-91e5-f21ac6a620cd" xlink:to="loc_srt_RangeAxis_2d248fe1-5025-4214-b9fa-e6c4eb94d61c" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_2d248fe1-5025-4214-b9fa-e6c4eb94d61c_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_2d248fe1-5025-4214-b9fa-e6c4eb94d61c" xlink:to="loc_srt_RangeMember_2d248fe1-5025-4214-b9fa-e6c4eb94d61c_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_86d7cada-58d6-4e2b-ab32-c2f92e9941a6" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_2d248fe1-5025-4214-b9fa-e6c4eb94d61c" xlink:to="loc_srt_RangeMember_86d7cada-58d6-4e2b-ab32-c2f92e9941a6" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_b8c11acf-1580-4dac-816b-f877e0bd5ff0" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_86d7cada-58d6-4e2b-ab32-c2f92e9941a6" xlink:to="loc_srt_MinimumMember_b8c11acf-1580-4dac-816b-f877e0bd5ff0" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_6347de7c-3468-4c24-8266-47b45a84d897" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_86d7cada-58d6-4e2b-ab32-c2f92e9941a6" xlink:to="loc_srt_MaximumMember_6347de7c-3468-4c24-8266-47b45a84d897" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/StockBasedCompensationWeightedAverageAssumptionsUsedinCalculatingFairValueofStockOptionDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#StockBasedCompensationWeightedAverageAssumptionsUsedinCalculatingFairValueofStockOptionDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/StockBasedCompensationWeightedAverageAssumptionsUsedinCalculatingFairValueofStockOptionDetails" xlink:type="extended" id="ifa0a2a528857465f81aa5f3a880f9a0b_StockBasedCompensationWeightedAverageAssumptionsUsedinCalculatingFairValueofStockOptionDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/StockBasedCompensationStockOptionsOutstandingExercisableandActivityDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#StockBasedCompensationStockOptionsOutstandingExercisableandActivityDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/StockBasedCompensationStockOptionsOutstandingExercisableandActivityDetail" xlink:type="extended" id="i4ed70dd0598344b18b017827e339c63a_StockBasedCompensationStockOptionsOutstandingExercisableandActivityDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/StockBasedCompensationStockOptionActivityDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#StockBasedCompensationStockOptionActivityDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/StockBasedCompensationStockOptionActivityDetails" xlink:type="extended" id="i1abaf5ca2c5a4c1e9367bb76e2befe8c_StockBasedCompensationStockOptionActivityDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/StockBasedCompensationRSUActivityDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#StockBasedCompensationRSUActivityDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/StockBasedCompensationRSUActivityDetails" xlink:type="extended" id="i61dc626e26fe44439d82cc4c39de1fe7_StockBasedCompensationRSUActivityDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/QuarterlyFinancialInformationunaudited" xlink:type="simple" xlink:href="ppg-20201231.xsd#QuarterlyFinancialInformationunaudited"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/QuarterlyFinancialInformationunaudited" xlink:type="extended" id="i13dbb58afb3c4b78a3997c0ee59b2696_QuarterlyFinancialInformationunaudited"/>
<link:roleRef roleURI="http://www.ppg.com/role/QuarterlyFinancialInformationTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#QuarterlyFinancialInformationTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/QuarterlyFinancialInformationTables" xlink:type="extended" id="ifb69593f7db84ca198a9bb9f81a57d37_QuarterlyFinancialInformationTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/QuarterlyFinancialInformationQuarterlyFinancialInformationunauditedDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#QuarterlyFinancialInformationQuarterlyFinancialInformationunauditedDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/QuarterlyFinancialInformationQuarterlyFinancialInformationunauditedDetails" xlink:type="extended" id="i4380f11e4386480ca4fc32ca889774dc_QuarterlyFinancialInformationQuarterlyFinancialInformationunauditedDetails"/>
<link:roleRef roleURI="http://www.ppg.com/role/RevenueRecognition" xlink:type="simple" xlink:href="ppg-20201231.xsd#RevenueRecognition"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/RevenueRecognition" xlink:type="extended" id="i2658f50f3233496a89fb0b61426b967e_RevenueRecognition"/>
<link:roleRef roleURI="http://www.ppg.com/role/RevenueRecognitionTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#RevenueRecognitionTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/RevenueRecognitionTables" xlink:type="extended" id="i84340d51bbd544a8b022315d6b796930_RevenueRecognitionTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/RevenueRecognitionScheduleOfRevenueDetails" xlink:type="simple" xlink:href="ppg-20201231.xsd#RevenueRecognitionScheduleOfRevenueDetails"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/RevenueRecognitionScheduleOfRevenueDetails" xlink:type="extended" id="i89483f1922c64238ae2d5ed3432abcb0_RevenueRecognitionScheduleOfRevenueDetails">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_15f23e16-651b-4053-9ebf-47813bc88198" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_223fb904-b0e9-40e0-b72e-0748c7b11c11" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskPercentage1"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_15f23e16-651b-4053-9ebf-47813bc88198" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_223fb904-b0e9-40e0-b72e-0748c7b11c11" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_8e1254f0-6639-4381-852e-e5d0fa1c14ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_15f23e16-651b-4053-9ebf-47813bc88198" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_8e1254f0-6639-4381-852e-e5d0fa1c14ed" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_68c3ceb1-592e-4ceb-abea-35cf9ec1fab5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_15f23e16-651b-4053-9ebf-47813bc88198" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_68c3ceb1-592e-4ceb-abea-35cf9ec1fab5" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_d6182bb4-03ec-4af6-874a-4645a4bc2e2f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_68c3ceb1-592e-4ceb-abea-35cf9ec1fab5" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_d6182bb4-03ec-4af6-874a-4645a4bc2e2f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_d6182bb4-03ec-4af6-874a-4645a4bc2e2f_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_d6182bb4-03ec-4af6-874a-4645a4bc2e2f" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_d6182bb4-03ec-4af6-874a-4645a4bc2e2f_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_29270003-da6c-4ab5-a8d3-28ce3396aa5f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_d6182bb4-03ec-4af6-874a-4645a4bc2e2f" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_29270003-da6c-4ab5-a8d3-28ce3396aa5f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerMember_bc97dae9-79a6-408d-8c6b-4ca61a5b9093" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_29270003-da6c-4ab5-a8d3-28ce3396aa5f" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerMember_bc97dae9-79a6-408d-8c6b-4ca61a5b9093" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_0cfce0a4-0925-49ca-b519-e032a4103ab8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_68c3ceb1-592e-4ceb-abea-35cf9ec1fab5" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_0cfce0a4-0925-49ca-b519-e032a4103ab8" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_0cfce0a4-0925-49ca-b519-e032a4103ab8_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_0cfce0a4-0925-49ca-b519-e032a4103ab8" xlink:to="loc_us-gaap_SegmentDomain_0cfce0a4-0925-49ca-b519-e032a4103ab8_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_905bd0c1-84ca-4429-bb42-bf633fd941d2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_0cfce0a4-0925-49ca-b519-e032a4103ab8" xlink:to="loc_us-gaap_SegmentDomain_905bd0c1-84ca-4429-bb42-bf633fd941d2" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PerformanceCoatingsSegmentMember_ad85f9f3-5927-4bf1-ab8c-689623112237" xlink:href="ppg-20201231.xsd#ppg_PerformanceCoatingsSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_905bd0c1-84ca-4429-bb42-bf633fd941d2" xlink:to="loc_ppg_PerformanceCoatingsSegmentMember_ad85f9f3-5927-4bf1-ab8c-689623112237" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IndustrialCoatingsSegmentMember_f205d979-602a-4977-ac5b-6f775b7ed24d" xlink:href="ppg-20201231.xsd#ppg_IndustrialCoatingsSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_905bd0c1-84ca-4429-bb42-bf633fd941d2" xlink:to="loc_ppg_IndustrialCoatingsSegmentMember_f205d979-602a-4977-ac5b-6f775b7ed24d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_dba95522-5ad4-4713-8c05-82dec0d60293" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductOrServiceAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_68c3ceb1-592e-4ceb-abea-35cf9ec1fab5" xlink:to="loc_srt_ProductOrServiceAxis_dba95522-5ad4-4713-8c05-82dec0d60293" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_dba95522-5ad4-4713-8c05-82dec0d60293_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductsAndServicesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_dba95522-5ad4-4713-8c05-82dec0d60293" xlink:to="loc_srt_ProductsAndServicesDomain_dba95522-5ad4-4713-8c05-82dec0d60293_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_dad7ecf0-c0af-4407-8275-faaa9f99f8e2" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductsAndServicesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_dba95522-5ad4-4713-8c05-82dec0d60293" xlink:to="loc_srt_ProductsAndServicesDomain_dad7ecf0-c0af-4407-8275-faaa9f99f8e2" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ServiceMember_c0d6f863-1088-4f63-bb43-acaa1ef2db92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ServiceMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_dad7ecf0-c0af-4407-8275-faaa9f99f8e2" xlink:to="loc_us-gaap_ServiceMember_c0d6f863-1088-4f63-bb43-acaa1ef2db92" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_ea89bf93-435e-4b51-8120-d148bfab218e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_StatementGeographicalAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_68c3ceb1-592e-4ceb-abea-35cf9ec1fab5" xlink:to="loc_srt_StatementGeographicalAxis_ea89bf93-435e-4b51-8120-d148bfab218e" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_ea89bf93-435e-4b51-8120-d148bfab218e_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementGeographicalAxis_ea89bf93-435e-4b51-8120-d148bfab218e" xlink:to="loc_srt_SegmentGeographicalDomain_ea89bf93-435e-4b51-8120-d148bfab218e_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_76a3b7da-afb9-4e58-a6cb-bfc3ae9c9f00" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_SegmentGeographicalDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementGeographicalAxis_ea89bf93-435e-4b51-8120-d148bfab218e" xlink:to="loc_srt_SegmentGeographicalDomain_76a3b7da-afb9-4e58-a6cb-bfc3ae9c9f00" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_NorthAmericaMember_70667d50-bee0-40ac-8fb6-028c85755003" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_NorthAmericaMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_76a3b7da-afb9-4e58-a6cb-bfc3ae9c9f00" xlink:to="loc_srt_NorthAmericaMember_70667d50-bee0-40ac-8fb6-028c85755003" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EMEAMember_c8ba5553-4e60-49e4-8703-b0f93bcb0f4f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EMEAMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_76a3b7da-afb9-4e58-a6cb-bfc3ae9c9f00" xlink:to="loc_us-gaap_EMEAMember_c8ba5553-4e60-49e4-8703-b0f93bcb0f4f" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_AsiaPacificMember_a7606438-72cc-45ca-9058-0739571e6eeb" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_AsiaPacificMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_76a3b7da-afb9-4e58-a6cb-bfc3ae9c9f00" xlink:to="loc_srt_AsiaPacificMember_a7606438-72cc-45ca-9058-0739571e6eeb" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_LatinAmericaMember_02a3d3c3-5d09-4653-8b7b-6b2828140568" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_LatinAmericaMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_76a3b7da-afb9-4e58-a6cb-bfc3ae9c9f00" xlink:to="loc_srt_LatinAmericaMember_02a3d3c3-5d09-4653-8b7b-6b2828140568" xlink:type="arc" order="3"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/ReportableBusinessSegmentInformation" xlink:type="simple" xlink:href="ppg-20201231.xsd#ReportableBusinessSegmentInformation"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ReportableBusinessSegmentInformation" xlink:type="extended" id="i2e1a9e387ef0423bb8bdb7c112244607_ReportableBusinessSegmentInformation"/>
<link:roleRef roleURI="http://www.ppg.com/role/ReportableBusinessSegmentInformationTables" xlink:type="simple" xlink:href="ppg-20201231.xsd#ReportableBusinessSegmentInformationTables"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ReportableBusinessSegmentInformationTables" xlink:type="extended" id="ibd9ba94297fc4db19a0e1d731516cabd_ReportableBusinessSegmentInformationTables"/>
<link:roleRef roleURI="http://www.ppg.com/role/ReportableBusinessSegmentInformationReportableSegmentInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#ReportableBusinessSegmentInformationReportableSegmentInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ReportableBusinessSegmentInformationReportableSegmentInformationDetail" xlink:type="extended" id="ib321599dd0c741398263e0e7ec727823_ReportableBusinessSegmentInformationReportableSegmentInformationDetail"/>
<link:roleRef roleURI="http://www.ppg.com/role/ReportableBusinessSegmentInformationReportableSegmentTablesDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#ReportableBusinessSegmentInformationReportableSegmentTablesDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ReportableBusinessSegmentInformationReportableSegmentTablesDetail" xlink:type="extended" id="ie6c8c10ea2c940bfa937038e9ed74f7b_ReportableBusinessSegmentInformationReportableSegmentTablesDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingRevenueReconcilingItemLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1ec76e27-cb9f-4422-88cd-63b61f520913" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_1ec76e27-cb9f-4422-88cd-63b61f520913" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_031f7450-8ffa-4707-9707-2d834b16edc7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_OperatingIncomeLoss_031f7450-8ffa-4707-9707-2d834b16edc7" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_CorporateExpenditure_b61adb3e-c628-4a16-84a1-58f77c9485d3" xlink:href="ppg-20201231.xsd#ppg_CorporateExpenditure"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_ppg_CorporateExpenditure_b61adb3e-c628-4a16-84a1-58f77c9485d3" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_24a59f65-dcee-4c49-81d9-589878a79354" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_24a59f65-dcee-4c49-81d9-589878a79354" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringCosts_c781f04d-4fb7-4a5d-bf39-318f8a068960" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestructuringCosts"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_RestructuringCosts_c781f04d-4fb7-4a5d-bf39-318f8a068960" xlink:type="arc" order="4"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_EnvironmentalRemediationCharge_dd74cc6a-c1be-442e-811c-3cec0966da62" xlink:href="ppg-20201231.xsd#ppg_EnvironmentalRemediationCharge"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_ppg_EnvironmentalRemediationCharge_dd74cc6a-c1be-442e-811c-3cec0966da62" xlink:type="arc" order="5"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_9f9c8cfe-8538-41b6-9956-3c2f902b7b6f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_9f9c8cfe-8538-41b6-9956-3c2f902b7b6f" xlink:type="arc" order="6"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetImpairmentCharges_9ebdc1e6-97b9-4b1c-9176-2505fe9feac6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetImpairmentCharges"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_OtherAssetImpairmentCharges_9ebdc1e6-97b9-4b1c-9176-2505fe9feac6" xlink:type="arc" order="7"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_Costsrelatedtocustomerassortmentchange_82605534-dc37-40a7-9721-c82168d286aa" xlink:href="ppg-20201231.xsd#ppg_Costsrelatedtocustomerassortmentchange"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_ppg_Costsrelatedtocustomerassortmentchange_82605534-dc37-40a7-9721-c82168d286aa" xlink:type="arc" order="8"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSaleOfOtherAssets_682a7796-d5bf-430b-a7d0-f9e49b60b068" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainLossOnSaleOfOtherAssets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_GainLossOnSaleOfOtherAssets_682a7796-d5bf-430b-a7d0-f9e49b60b068" xlink:type="arc" order="9"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IncomeLossFromContinuingOperationsBeforeIncomeTaxes_0927e923-4eb7-483d-98fd-e8484ae1c258" xlink:href="ppg-20201231.xsd#ppg_IncomeLossFromContinuingOperationsBeforeIncomeTaxes"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_ppg_IncomeLossFromContinuingOperationsBeforeIncomeTaxes_0927e923-4eb7-483d-98fd-e8484ae1c258" xlink:type="arc" order="10"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationAndAmortization_3b368a1a-8bc2-45d5-803b-13569894e21d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationAndAmortization"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_DepreciationAndAmortization_3b368a1a-8bc2-45d5-803b-13569894e21d" xlink:type="arc" order="11"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_06708ffb-b91e-485e-8cd8-fc180ea3a86d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_06708ffb-b91e-485e-8cd8-fc180ea3a86d" xlink:type="arc" order="12"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_89dc2261-db2e-4f38-a254-1e8c538c2cb5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_Assets_89dc2261-db2e-4f38-a254-1e8c538c2cb5" xlink:type="arc" order="13"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestments_f951970a-ecb8-41f5-8415-6fd7d4b60606" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityMethodInvestments"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_EquityMethodInvestments_f951970a-ecb8-41f5-8415-6fd7d4b60606" xlink:type="arc" order="14"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAdditions_faefa0a0-46f1-4cb5-b3e7-c35e947483be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAdditions"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAdditions_faefa0a0-46f1-4cb5-b3e7-c35e947483be" xlink:type="arc" order="15"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_AccountsReceivableCreditLossExpenseReversalCARESAct_dbb36dbf-a948-40d4-82d1-5b0ee76f2e1c" xlink:href="ppg-20201231.xsd#ppg_AccountsReceivableCreditLossExpenseReversalCARESAct"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_ppg_AccountsReceivableCreditLossExpenseReversalCARESAct_dbb36dbf-a948-40d4-82d1-5b0ee76f2e1c" xlink:type="arc" order="16"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnusualOrInfrequentItemLossGross_ef631377-9b36-43f6-9ae2-ad6b804d7fcf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnusualOrInfrequentItemLossGross"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_UnusualOrInfrequentItemLossGross_ef631377-9b36-43f6-9ae2-ad6b804d7fcf" xlink:type="arc" order="17"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_6a6bd755-15d2-4821-987f-7870b7bc73b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_6a6bd755-15d2-4821-987f-7870b7bc73b0" xlink:type="arc" order="18"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementExpense_16cc8ecb-f9fa-408a-b91a-88830fabaa37" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LitigationSettlementExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_LitigationSettlementExpense_16cc8ecb-f9fa-408a-b91a-88830fabaa37" xlink:type="arc" order="19"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable_484b2368-08d5-4db1-8217-8a5116cecfd0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_02a47852-2c5d-4300-92f2-e5ff447dbf2f" xlink:to="loc_us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable_484b2368-08d5-4db1-8217-8a5116cecfd0" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_41ece88b-6c64-469b-8fdf-573b663cb3c1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable_484b2368-08d5-4db1-8217-8a5116cecfd0" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_41ece88b-6c64-469b-8fdf-573b663cb3c1" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_41ece88b-6c64-469b-8fdf-573b663cb3c1_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_41ece88b-6c64-469b-8fdf-573b663cb3c1" xlink:to="loc_us-gaap_SegmentDomain_41ece88b-6c64-469b-8fdf-573b663cb3c1_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_a98d1ebf-689d-47e0-815a-80e563d1ed2a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_41ece88b-6c64-469b-8fdf-573b663cb3c1" xlink:to="loc_us-gaap_SegmentDomain_a98d1ebf-689d-47e0-815a-80e563d1ed2a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_PerformanceCoatingsSegmentMember_d90aa982-9de2-4e10-86ed-3ac93942e1e7" xlink:href="ppg-20201231.xsd#ppg_PerformanceCoatingsSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_a98d1ebf-689d-47e0-815a-80e563d1ed2a" xlink:to="loc_ppg_PerformanceCoatingsSegmentMember_d90aa982-9de2-4e10-86ed-3ac93942e1e7" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_IndustrialCoatingsSegmentMember_70f9d6a9-16cc-43d0-ba72-9ad69844157c" xlink:href="ppg-20201231.xsd#ppg_IndustrialCoatingsSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_a98d1ebf-689d-47e0-815a-80e563d1ed2a" xlink:to="loc_ppg_IndustrialCoatingsSegmentMember_70f9d6a9-16cc-43d0-ba72-9ad69844157c" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsAxis_f11c0527-6aaf-41dd-8cef-1e790b32832e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable_484b2368-08d5-4db1-8217-8a5116cecfd0" xlink:to="loc_srt_ConsolidationItemsAxis_f11c0527-6aaf-41dd-8cef-1e790b32832e" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsDomain_f11c0527-6aaf-41dd-8cef-1e790b32832e_default" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ConsolidationItemsAxis_f11c0527-6aaf-41dd-8cef-1e790b32832e" xlink:to="loc_srt_ConsolidationItemsDomain_f11c0527-6aaf-41dd-8cef-1e790b32832e_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsDomain_00b26797-d29b-416d-991d-8b18239991b6" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ConsolidationItemsDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ConsolidationItemsAxis_f11c0527-6aaf-41dd-8cef-1e790b32832e" xlink:to="loc_srt_ConsolidationItemsDomain_00b26797-d29b-416d-991d-8b18239991b6" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingSegmentsMember_17defaec-9e0f-4240-98fd-caf6ce38944f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingSegmentsMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_00b26797-d29b-416d-991d-8b18239991b6" xlink:to="loc_us-gaap_OperatingSegmentsMember_17defaec-9e0f-4240-98fd-caf6ce38944f" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateNonSegmentMember_5b1414bb-080f-41c2-b27f-36c44e3c7520" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CorporateNonSegmentMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_00b26797-d29b-416d-991d-8b18239991b6" xlink:to="loc_us-gaap_CorporateNonSegmentMember_5b1414bb-080f-41c2-b27f-36c44e3c7520" xlink:type="arc" order="1"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/ReportableBusinessSegmentInformationGeographicInformationDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#ReportableBusinessSegmentInformationGeographicInformationDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ReportableBusinessSegmentInformationGeographicInformationDetail" xlink:type="extended" id="id6c322c54e754569b300f8ae64993b9a_ReportableBusinessSegmentInformationGeographicInformationDetail">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_56f1d6f5-0a3a-458b-9154-4b16c68641fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingRevenueReconcilingItemLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_66ea4a76-8d72-47fa-8bed-aa49e98069bf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_56f1d6f5-0a3a-458b-9154-4b16c68641fd" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_66ea4a76-8d72-47fa-8bed-aa49e98069bf" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_88011410-d95b-4e14-97fb-c7252a32de26" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_56f1d6f5-0a3a-458b-9154-4b16c68641fd" xlink:to="loc_us-gaap_OperatingIncomeLoss_88011410-d95b-4e14-97fb-c7252a32de26" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_e7e46951-70b0-4562-9808-fac399cc09a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_56f1d6f5-0a3a-458b-9154-4b16c68641fd" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_e7e46951-70b0-4562-9808-fac399cc09a9" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable_33227058-3630-42e0-a9d7-b572fe6e7be5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingRevenueReconcilingItemLineItems_56f1d6f5-0a3a-458b-9154-4b16c68641fd" xlink:to="loc_us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable_33227058-3630-42e0-a9d7-b572fe6e7be5" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_RegionReportingInformationByRegionAxis_623f66e6-efa0-4e58-b6ef-a7ad0ea7e97d" xlink:href="ppg-20201231.xsd#ppg_RegionReportingInformationByRegionAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ReconciliationOfRevenueFromSegmentsToConsolidatedTable_33227058-3630-42e0-a9d7-b572fe6e7be5" xlink:to="loc_ppg_RegionReportingInformationByRegionAxis_623f66e6-efa0-4e58-b6ef-a7ad0ea7e97d" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ReportingRegionDomain_623f66e6-efa0-4e58-b6ef-a7ad0ea7e97d_default" xlink:href="ppg-20201231.xsd#ppg_ReportingRegionDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_ppg_RegionReportingInformationByRegionAxis_623f66e6-efa0-4e58-b6ef-a7ad0ea7e97d" xlink:to="loc_ppg_ReportingRegionDomain_623f66e6-efa0-4e58-b6ef-a7ad0ea7e97d_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_ReportingRegionDomain_ddf190e9-8fe2-41fa-b521-bcb3504ce85e" xlink:href="ppg-20201231.xsd#ppg_ReportingRegionDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ppg_RegionReportingInformationByRegionAxis_623f66e6-efa0-4e58-b6ef-a7ad0ea7e97d" xlink:to="loc_ppg_ReportingRegionDomain_ddf190e9-8fe2-41fa-b521-bcb3504ce85e" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_UnitedStatesandCanadaMember_2ce5d69a-c5ad-4d9a-b285-1f53b9bc8e63" xlink:href="ppg-20201231.xsd#ppg_UnitedStatesandCanadaMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ReportingRegionDomain_ddf190e9-8fe2-41fa-b521-bcb3504ce85e" xlink:to="loc_ppg_UnitedStatesandCanadaMember_2ce5d69a-c5ad-4d9a-b285-1f53b9bc8e63" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_EuropeMiddleEastAndAfricaMember_7967aad6-2c52-4ec7-aa32-ea544ed677c4" xlink:href="ppg-20201231.xsd#ppg_EuropeMiddleEastAndAfricaMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ReportingRegionDomain_ddf190e9-8fe2-41fa-b521-bcb3504ce85e" xlink:to="loc_ppg_EuropeMiddleEastAndAfricaMember_7967aad6-2c52-4ec7-aa32-ea544ed677c4" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_AsiaMember_bac37092-6798-4798-990e-d8671d976a79" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_AsiaMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ReportingRegionDomain_ddf190e9-8fe2-41fa-b521-bcb3504ce85e" xlink:to="loc_srt_AsiaMember_bac37092-6798-4798-990e-d8671d976a79" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_ppg_OtherAmericasMember_5c9cb752-e5cf-40b3-bc03-6e68c3e1896c" xlink:href="ppg-20201231.xsd#ppg_OtherAmericasMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ppg_ReportingRegionDomain_ddf190e9-8fe2-41fa-b521-bcb3504ce85e" xlink:to="loc_ppg_OtherAmericasMember_5c9cb752-e5cf-40b3-bc03-6e68c3e1896c" xlink:type="arc" order="3"/>
</link:definitionLink>
<link:roleRef roleURI="http://www.ppg.com/role/ScheduleIIValuationandQualifyingAccountsDetail" xlink:type="simple" xlink:href="ppg-20201231.xsd#ScheduleIIValuationandQualifyingAccountsDetail"/>
<link:definitionLink xlink:role="http://www.ppg.com/role/ScheduleIIValuationandQualifyingAccountsDetail" xlink:type="extended" id="i3e9a8a872ef54147931042d7b50923b6_ScheduleIIValuationandQualifyingAccountsDetail">
<link:loc xlink:type="locator" xlink:label="loc_srt_ValuationAndQualifyingAccountsDisclosureLineItems_b51907cd-2176-48cd-bf0c-26eaa8881061" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ValuationAndQualifyingAccountsDisclosureLineItems"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_daced1e0-e10d-42e6-9081-dd045d5a7110" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MovementInValuationAllowancesAndReservesRollForward"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ValuationAndQualifyingAccountsDisclosureLineItems_b51907cd-2176-48cd-bf0c-26eaa8881061" xlink:to="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_daced1e0-e10d-42e6-9081-dd045d5a7110" xlink:type="arc" order="0"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesBalance_8bca47c3-33e2-4321-80bf-46bfc872f777" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesBalance"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_daced1e0-e10d-42e6-9081-dd045d5a7110" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesBalance_8bca47c3-33e2-4321-80bf-46bfc872f777" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesChargedToCostAndExpense_2afa6668-6def-4f8b-9b22-ca9b01558ae2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesChargedToCostAndExpense"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_daced1e0-e10d-42e6-9081-dd045d5a7110" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesChargedToCostAndExpense_2afa6668-6def-4f8b-9b22-ca9b01558ae2" xlink:type="arc" order="2"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesDeductions_f92826ef-f16b-4f0d-b811-1ad6b948963a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesDeductions"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_daced1e0-e10d-42e6-9081-dd045d5a7110" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesDeductions_f92826ef-f16b-4f0d-b811-1ad6b948963a" xlink:type="arc" order="3"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesBalance_fe14e622-4eb9-488d-a50d-9215b9d266e1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesBalance"/>
<link:loc xlink:type="locator" xlink:label="loc_srt_ValuationAndQualifyingAccountsDisclosureTable_b0b7e8ad-ce53-4c67-b1c3-a05397ea7df8" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ValuationAndQualifyingAccountsDisclosureTable"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_srt_ValuationAndQualifyingAccountsDisclosureLineItems_b51907cd-2176-48cd-bf0c-26eaa8881061" xlink:to="loc_srt_ValuationAndQualifyingAccountsDisclosureTable_b0b7e8ad-ce53-4c67-b1c3-a05397ea7df8" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesTypeAxis_1d9c927d-8030-488e-97d9-5cd6aab3c38a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesTypeAxis"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_srt_ValuationAndQualifyingAccountsDisclosureTable_b0b7e8ad-ce53-4c67-b1c3-a05397ea7df8" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesTypeAxis_1d9c927d-8030-488e-97d9-5cd6aab3c38a" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesDomain_1d9c927d-8030-488e-97d9-5cd6aab3c38a_default" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ValuationAllowancesAndReservesTypeAxis_1d9c927d-8030-488e-97d9-5cd6aab3c38a" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesDomain_1d9c927d-8030-488e-97d9-5cd6aab3c38a_default" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesDomain_0c995c8d-3aa4-477e-86eb-d9053c30c8dc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowancesAndReservesDomain"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ValuationAllowancesAndReservesTypeAxis_1d9c927d-8030-488e-97d9-5cd6aab3c38a" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesDomain_0c995c8d-3aa4-477e-86eb-d9053c30c8dc" xlink:type="arc" order="1"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForCreditLossMember_dc2a843f-89c1-406b-ace0-5dfb7639b62d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllowanceForCreditLossMember"/>
<link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ValuationAllowancesAndReservesDomain_0c995c8d-3aa4-477e-86eb-d9053c30c8dc" xlink:to="loc_us-gaap_AllowanceForCreditLossMember_dc2a843f-89c1-406b-ace0-5dfb7639b62d" xlink:type="arc" order="0"/>
</link:definitionLink>
</link:linkbase>

2 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/03/21  PPG Industries Inc.               424B2                  1:515K                                   Donnelley … Solutions/FA
 3/01/21  PPG Industries Inc.               424B5                  1:495K                                   Donnelley … Solutions/FA

31 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

10/20/20  PPG Industries Inc.               10-Q        9/30/20   76:9.1M
 5/19/20  PPG Industries Inc.               8-K:1,2,9   5/14/20   14:525K                                   Donnelley … Solutions/FA
 4/17/20  PPG Industries Inc.               8-K:1,2,9   4/14/20   13:722K
 3/26/20  PPG Industries Inc.               8-K:5,9     3/20/20   13:439K
 9/04/19  PPG Industries Inc.               8-K:1,2,9   8/30/19   13:1.1M
 8/15/19  PPG Industries Inc.               8-K:1,2,9   8/15/19   13:315K                                   Donnelley … Solutions/FA
 2/21/19  PPG Industries Inc.               10-K       12/31/18  125:21M
10/19/18  PPG Industries Inc.               10-Q        9/30/18   85:10M
 2/27/18  PPG Industries Inc.               8-K:1,2,9   2/27/18    4:259K                                   Donnelley … Solutions/FA
11/03/16  PPG Industries Inc.               8-K:1,2,9  11/03/16    3:98K                                    Donnelley … Solutions/FA
 3/10/16  PPG Industries Inc.               DEF 14A     4/21/16    1:2.7M                                   Toppan Merrill-FA
 6/18/15  PPG Industries Inc.               8-K:5,7,8,9 6/12/15    3:1.2M
 3/13/15  PPG Industries Inc.               8-K:1,2,9   3/13/15    3:92K                                    Donnelley … Solutions/FA
11/12/14  PPG Industries Inc.               8-K:1,2,9  11/12/14    4:212K                                   Donnelley … Solutions/FA
10/24/14  PPG Industries Inc.               10-Q        9/30/14   86:10M
 7/23/14  PPG Industries Inc.               10-Q        6/30/14   87:11M
 4/24/14  PPG Industries Inc.               10-Q        3/31/14   93:10M
 4/29/13  PPG Industries Inc.               10-Q        3/31/13   98:12M
 2/21/13  PPG Industries Inc.               10-K       12/31/12  142:28M
 8/03/12  PPG Industries Inc.               8-K:1,2,9   7/31/12    4:207K                                   Donnelley … Solutions/FA
 7/30/12  PPG Industries Inc.               10-Q        6/30/12   93:9.2M                                   Donnelley … Solutions/FA
 2/16/12  PPG Industries Inc.               10-K       12/31/11  139:20M                                    Donnelley … Solutions/FA
 8/01/11  PPG Industries Inc.               10-Q        6/30/11   91:7.9M                                   Donnelley … Solutions/FA
 3/10/11  PPG Industries Inc.               DEF 14A     4/21/11    1:1.3M                                   Donnelley … Solutions/FA
11/12/10  PPG Industries Inc.               8-K:1,9    11/08/10    5:235K                                   Donnelley … Solutions/FA
 2/18/10  PPG Industries Inc.               10-K       12/31/09   55:6.7M                                   Donnelley … Solutions/FA
 3/18/08  PPG Industries Inc.               8-K:1,9     3/13/08    6:492K                                   Bowne BCL/FA
 2/21/08  PPG Industries Inc.               10-K       12/31/07   18:3.5M                                   Donnelley … Solutions/FA
 2/15/05  PPG Industries Inc.               8-K:1,5,9   2/15/05    6:100K                                   Donnelley Fi… Express/FA
 7/26/04  PPG Industries Inc.               10-Q        6/30/04    9:865K                                   Donnelley … Solutions/FA
 2/24/98  PPG Industries Inc.               10-K       12/31/97   12:374K                                   Donnelley R R & S… 04/FA
↑Top
Filing Submission 0000079879-21-000008   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)
Copyright © 2024 Fran Finnegan & Company LLC – All Rights Reserved.
About — Privacy — Redactions — Help — Sun., Apr. 28, 12:21:46.3pm ET