| | | | | | | | | | | | | | | | | | | | | |
<?xml version="1.0" encoding="windows-1252"?> |
<!-- XBRL Document Created with Wdesk from Workiva --> |
<!-- Copyright 2022 Workiva --> |
<!-- r:8f839ccd-8d5f-4662-8ca7-d70849f50740,g:c0d4825f-b791-4b82-bcdf-f001d5370e40 --> |
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"> |
| <link:roleRef roleURI="http://www.2seventybio.com/role/DocumentandEntityInformationDocument" xlink:type="simple" xlink:href="tvst-20220907.xsd#DocumentandEntityInformationDocument"/> |
| <link:presentationLink xlink:role="http://www.2seventybio.com/role/DocumentandEntityInformationDocument" xlink:type="extended"> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CoverAbstract"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_85c90969-36dc-43c5-a67b-c77cf3a269fb" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentType"/> |
| | <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_DocumentType_85c90969-36dc-43c5-a67b-c77cf3a269fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_874ad8a1-be99-4891-9d40-51a922761035" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentPeriodEndDate"/> |
| | <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_DocumentPeriodEndDate_874ad8a1-be99-4891-9d40-51a922761035" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_acf33a83-da75-455f-9e87-76f9f57a5817" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityRegistrantName"/> |
| | <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityRegistrantName_acf33a83-da75-455f-9e87-76f9f57a5817" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_40e07cd4-a221-46d6-be87-1259fcf8d97c" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityIncorporationStateCountryCode"/> |
| | <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityIncorporationStateCountryCode_40e07cd4-a221-46d6-be87-1259fcf8d97c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_8e07bb8b-5399-44b3-ac5c-476b9c0ac53a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFileNumber"/> |
| | <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityFileNumber_8e07bb8b-5399-44b3-ac5c-476b9c0ac53a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_ba976e1c-eef1-47b9-a45e-05dbe0cb224c" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityTaxIdentificationNumber"/> |
| | <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityTaxIdentificationNumber_ba976e1c-eef1-47b9-a45e-05dbe0cb224c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_d1447761-7a7a-4198-b4c0-9d29a5005ef2" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine1"/> |
| | <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityAddressAddressLine1_d1447761-7a7a-4198-b4c0-9d29a5005ef2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_87eed9b8-705e-404f-be4f-21f63e821776" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressCityOrTown"/> |
| | <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityAddressCityOrTown_87eed9b8-705e-404f-be4f-21f63e821776" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_246d4d11-1e90-45ba-b0f8-852bbe295e6e" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressStateOrProvince"/> |
| | <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityAddressStateOrProvince_246d4d11-1e90-45ba-b0f8-852bbe295e6e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_8ce034f7-289a-48a1-bf4b-2f6de4347647" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressPostalZipCode"/> |
| | <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityAddressPostalZipCode_8ce034f7-289a-48a1-bf4b-2f6de4347647" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_7248dd26-a792-45a6-90ea-08bf757bf24a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CityAreaCode"/> |
| | <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_CityAreaCode_7248dd26-a792-45a6-90ea-08bf757bf24a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_c59be71d-e346-47ce-a0aa-2006e7756c22" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LocalPhoneNumber"/> |
| | <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_LocalPhoneNumber_c59be71d-e346-47ce-a0aa-2006e7756c22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_109c546c-646b-4b05-b193-9831bb5f7337" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_WrittenCommunications"/> |
| | <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_WrittenCommunications_109c546c-646b-4b05-b193-9831bb5f7337" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_a8cd1310-6205-490a-b756-b705224635d8" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SolicitingMaterial"/> |
| | <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_SolicitingMaterial_a8cd1310-6205-490a-b756-b705224635d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_7921ea42-9dec-4fbc-9def-6c071555db5b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_PreCommencementTenderOffer"/> |
| | <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_PreCommencementTenderOffer_7921ea42-9dec-4fbc-9def-6c071555db5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_62cfd4e8-22d6-475f-a8bb-e1ea4db286bd" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_PreCommencementIssuerTenderOffer"/> |
| | <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_62cfd4e8-22d6-475f-a8bb-e1ea4db286bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_6f8b30f0-ce2f-4646-b871-e6c7451d471d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_Security12bTitle"/> |
| | <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_Security12bTitle_6f8b30f0-ce2f-4646-b871-e6c7451d471d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_d8c9edb6-20cb-4fcf-ac12-b5ad6905937e" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_TradingSymbol"/> |
| | <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_TradingSymbol_d8c9edb6-20cb-4fcf-ac12-b5ad6905937e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_d1c12499-9f47-474f-b5b9-d1e3156a92ef" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SecurityExchangeName"/> |
| | <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_SecurityExchangeName_d1c12499-9f47-474f-b5b9-d1e3156a92ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_f586fafc-9923-48ac-9eec-87616ef3085a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany"/> |
| | <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityEmergingGrowthCompany_f586fafc-9923-48ac-9eec-87616ef3085a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityExTransitionPeriod_c827bdd6-66e0-4a1a-bc85-36a292a7ffc0" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityExTransitionPeriod"/> |
| | <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityExTransitionPeriod_c827bdd6-66e0-4a1a-bc85-36a292a7ffc0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_556cbf57-8b46-41b8-b6cf-b6aa67d91cf4" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCentralIndexKey"/> |
| | <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_EntityCentralIndexKey_556cbf57-8b46-41b8-b6cf-b6aa67d91cf4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_ce5e6c3e-3809-496c-853f-8da84c9dcdd2" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_AmendmentFlag"/> |
| | <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3a672a22-a305-400f-8692-8c1d075f13ec" xlink:to="loc_dei_AmendmentFlag_ce5e6c3e-3809-496c-853f-8da84c9dcdd2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | </link:presentationLink> |
| </link:linkbase> |