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AIM ImmunoTech Inc. – ‘10-K’ for 12/31/17 – ‘EX-10.45’

On:  Friday, 3/30/18, at 5:23pm ET   ·   For:  12/31/17   ·   Accession #:  1493152-18-4291   ·   File #:  1-27072

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  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/30/18  AIM ImmunoTech Inc.               10-K       12/31/17   88:14M                                    M2 Compliance/FA

Annual Report   —   Form 10-K   —   Sect. 13 / 15(d) – SEA’34
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   1.27M 
 2: EX-4.8      Instrument Defining the Rights of Security Holders  HTML     67K 
 3: EX-10.45    Material Contract                                   HTML     29K 
 4: EX-10.46    Material Contract                                   HTML     29K 
 5: EX-10.47    Material Contract                                   HTML     30K 
 6: EX-10.48    Material Contract                                   HTML     30K 
 7: EX-10.57    Material Contract                                   HTML    214K 
14: EX-10.58    Material Contract                                   HTML    194K 
15: EX-10.59    Material Contract                                   HTML     40K 
16: EX-21       Subsidiaries List                                   HTML     24K 
17: EX-23.1     Consent of Experts or Counsel                       HTML     26K 
18: EX-31.1     Certification -- §302 - SOA'02                      HTML     32K 
19: EX-31.2     Certification -- §302 - SOA'02                      HTML     32K 
20: EX-32.1     Certification -- §906 - SOA'02                      HTML     26K 
21: EX-32.2     Certification -- §906 - SOA'02                      HTML     26K 
22: R1          Document and Entity Information                     HTML     52K 
23: R2          Consolidated Balance Sheets                         HTML     92K 
24: R3          Consolidated Balance Sheets (Parenthetical)         HTML     43K 
25: R4          Consolidated Statements of Comprehensive Loss       HTML     78K 
26: R5          Consolidated Statements of Changes in               HTML     72K 
                Stockholders' Equity                                             
27: R6          Consolidated Statements of Cash Flows               HTML    112K 
28: R7          Business                                            HTML     35K 
29: R8          Summary of Significant Accounting Policies          HTML     56K 
30: R9          Inventories                                         HTML     32K 
31: R10         Marketable Securities                               HTML     50K 
32: R11         Patents, Trademark Rights and Other Intangibles     HTML     29K 
                (FASB ASC 350-30 General Intangibles Other than                  
                Goodwill)                                                        
33: R12         Accrued Expenses                                    HTML     31K 
34: R13         Stockholders' Equity                                HTML    186K 
35: R14         Segment and Related Information                     HTML     28K 
36: R15         Research, Consulting and Supply Agreements          HTML     41K 
37: R16         401(k) Plan                                         HTML     30K 
38: R17         Royalties, License and Employment Agreements        HTML     33K 
39: R18         Leases                                              HTML     28K 
40: R19         Income Taxes (FASB ASC 740 Income Taxes)            HTML     40K 
41: R20         Notes Payable                                       HTML     29K 
42: R21         Certain Relationships and Related Transactions      HTML     30K 
43: R22         Concentrations of Credit Risk                       HTML     27K 
44: R23         Fair Value                                          HTML     76K 
45: R24         Subsequent Events                                   HTML     35K 
46: R25         Summary of Significant Accounting Policies          HTML     97K 
                (Policies)                                                       
47: R26         Summary of Significant Accounting Policies          HTML     31K 
                (Tables)                                                         
48: R27         Inventories (Tables)                                HTML     31K 
49: R28         Marketable Securities (Tables)                      HTML     52K 
50: R29         Accrued Expenses (Tables)                           HTML     30K 
51: R30         Stockholders' Equity (Tables)                       HTML    162K 
52: R31         Income Taxes (FASB ASC 740 Income Taxes) (Tables)   HTML     33K 
53: R32         Fair Value (Tables)                                 HTML     65K 
54: R33         Business (Details Narrative)                        HTML     48K 
55: R34         Summary of Significant Accounting Policies          HTML     64K 
                (Details Narrative)                                              
56: R35         Summary of Significant Accounting Policies -        HTML     36K 
                Schedule of Property and Equipment (Details)                     
57: R36         Inventories (Details Narrative)                     HTML     27K 
58: R37         Inventories - Schedule of Inventories (Details)     HTML     32K 
59: R38         Marketable Securities (Details Narrative)           HTML     27K 
60: R39         Marketable Securities - Schedule of Available for   HTML     42K 
                Sale (Details)                                                   
61: R40         Marketable Securities - Schedule of Investments     HTML     46K 
                with Continuous Unrealized Losses (Details)                      
62: R41         Patents, Trademark Rights and Other Intangibles     HTML     50K 
                (FASB ASC 350-30 General Intangibles Other than                  
                Goodwill) (Details Narrative)                                    
63: R42         Accrued Expenses - Schedule of Accrued Expenses     HTML     37K 
                (Details)                                                        
64: R43         Stockholders' Equity (Details Narrative)            HTML    291K 
65: R44         Stockholders' Equity - Schedule of Options and      HTML     42K 
                Equity Estimated Based on Weighted Average                       
                Assumptions (Details)                                            
66: R45         Stockholders' Equity - Schedule of Stock Option     HTML     99K 
                Activity Plans (Details)                                         
67: R46         Stockholders' Equity - Schedule of Stock Option     HTML     95K 
                Activity (Details)                                               
68: R47         Stockholders' Equity - Schedule of Unvested Stock   HTML     66K 
                Option Activity (Details)                                        
69: R48         Stockholders' Equity - Schedule of Warrants         HTML     73K 
                Outstanding and Exercisable (Details)                            
70: R49         Segment and Related Information (Details            HTML     26K 
                Narrative)                                                       
71: R50         Research, Consulting and Supply Agreements          HTML     66K 
                (Details Narrative)                                              
72: R51         401(k) Plan (Details Narrative)                     HTML     35K 
73: R52         Royalties, License and Employment Agreements        HTML     52K 
                (Details Narrative)                                              
74: R53         Leases (Details Narrative)                          HTML     26K 
75: R54         Income Taxes (FASB ASC 740 Income Taxes) (Details   HTML     52K 
                Narrative)                                                       
76: R55         Income Taxes (FASB ASC 740 Income Taxes) -          HTML     47K 
                Schedule of Deferred Tax Assets and Liabilities                  
                (Details)                                                        
77: R56         Note Payable (Details Narrative)                    HTML     41K 
78: R57         Certain Relationships and Related Transactions      HTML     43K 
                (Details Narrative)                                              
79: R58         Concentrations of Credit Risk (Details Narrative)   HTML     28K 
80: R59         Fair Value (Details Narrative)                      HTML     33K 
81: R60         Fair Value - Schedule of Assumptions to Estimate    HTML     64K 
                Fair Value of Warrants (Details)                                 
82: R61         Fair Value - Schedule of Range of Probabilities     HTML     29K 
                (Details)                                                        
83: R62         Fair Value - Schedule of Assets and Liabilities     HTML     34K 
                Measured at Fair Value on a Recurring Basis                      
                (Details)                                                        
84: R63         Fair Value - Schedule of Changes in Level 3         HTML     34K 
                Liabilities Measured at Fair Value on a Recurring                
                Basis (Details)                                                  
85: R64         Subsequent Events (Details Narrative)               HTML     71K 
87: XML         IDEA XML File -- Filing Summary                      XML    143K 
86: EXCEL       IDEA Workbook of Financial Reports                  XLSX     93K 
 8: EX-101.INS  XBRL Instance -- heb-20171231                        XML   2.08M 
10: EX-101.CAL  XBRL Calculations -- heb-20171231_cal                XML    163K 
11: EX-101.DEF  XBRL Definitions -- heb-20171231_def                 XML    729K 
12: EX-101.LAB  XBRL Labels -- heb-20171231_lab                      XML   1.20M 
13: EX-101.PRE  XBRL Presentations -- heb-20171231_pre               XML    910K 
 9: EX-101.SCH  XBRL Schema -- heb-20171231                          XSD    209K 
88: ZIP         XBRL Zipped Folder -- 0001493152-18-004291-xbrl      Zip    162K 


‘EX-10.45’   —   Material Contract


This Exhibit is an HTML Document rendered as filed.  [ Alternative Formats ]



 

AMENDMENT NO. 1 TO

EARLY ACCESS AGREEMENT

 

This First Amendment to the Early Access Agreement (the “Agreement”) dated 20th May 2016, by and between Hemispherx Biopharma, Inc. (“HEMISPHERX”), and Impatients N.V. (“IMPATIENTS”), who are each a “Party” and together the “Parties” to the Agreement, is entered into as of December 13, 2106 (the “Amendment No. 1 Effective Date”).

 

RECITALS

 

WHEREAS, HEMISPHERX and IMPATIENTS are Parties to and Early Access Agreement for HEMISPHERX’S Product, Ampligen (rintatolimod);

 

WHEREAS, the Parties wish to amend the Agreement as set forth below;

 

NOW, THEREFORE, the Parties hereby agree as follows:

 

Definitions and References. Except as set forth herein, capitalized terms not otherwise defined or amended in the Amendment shall have the meaning ascribed to them in the Agreement. References to Articles or Sections are the same with all of their subparts as they appear in the Agreement.

 

1. Amendment to the Agreement: Effective as of the Amendment No. 1 Effective Date, the Agreement shall be amended as follows:

 

In Clause 1.10 the text “and/or treatment of pancreatic cancer” shall be added to the definition of Field, such that Clause 1.10 reads

 

“Field” means treatment of chronic fatigue syndrome and/or the treatment of pancreatic cancer.

 

In Exhibit 9 the text “for patients with Chronic Fatigue Syndrome” shall be added in the second line such that the first paragraph reads:

 

To the extent permitted by Applicable Law, IMPATIENTS shall use its reasonable commercial efforts to collect the following data in relation to the EAP for patients with Chronic Fatigue Syndrome;

 

2. Effect of the Amendment. From and after the Amendment No. 1 Effective Date, all references to the Agreement shall mean the Agreement as amended by this Agreement. Except as expressly amended by the Amendment, all of the provisions of the original Early Access Program shall remain in full force and effect.

 

 C: 
  C: 1 

 

 

IN WITNESS WHEREOF, the respective Parties hereto have duly executed this Amendment as of the Amendment No. 1 Effective Date above. The persons executing this Amendment represent and warrant that they have the full power and authority to enter into this Amendment on behalf of the persons or entities for whom they are signing.

 

HEMISPHERX BIOPHARMA, INC.  
a Delaware corporation  
     
By: /s/ Ronald Brus, MD  
Title: CEO  

 

IMPATIENTS N.V.  
a Dutch limited liability company  
     
By: /s/ Thomas K. Equals  
Title: Chairman and CEO  

 

 C: 
 2 

 

 


7 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 4/19/24  AIM ImmunoTech Inc.               S-1                    6:628K                                   M2 Compliance LLC/FA
 4/01/24  AIM ImmunoTech Inc.               10-K       12/31/23   84:8.7M                                   M2 Compliance LLC/FA
 3/31/23  AIM ImmunoTech Inc.               10-K       12/31/22   87:8.7M                                   M2 Compliance LLC/FA
 8/15/22  AIM ImmunoTech Inc.               10-Q        6/30/22   72:6M                                     M2 Compliance LLC/FA
 5/13/22  AIM ImmunoTech Inc.               10-Q        3/31/22   68:5.6M                                   M2 Compliance LLC/FA
 3/31/22  AIM ImmunoTech Inc.               10-K       12/31/21   90:9.3M                                   M2 Compliance LLC/FA
 3/31/21  AIM ImmunoTech Inc.               10-K       12/31/20   94:7.6M                                   M2 Compliance LLC/FA
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Filing Submission 0001493152-18-004291   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)

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