| | | | | | | | | | | | | | | | | | | | | |
<?xml version="1.0" encoding="windows-1252"?> |
<!-- Field: Doc-Info; Name: Generator; Value: GoFiler Complete; Version: 5.15b --> |
<!-- Field: Doc-Info; Name: VendorURI; Value: https://www.novaworks.com --> |
<!-- Field: Doc-Info; Name: Status; Value: 0x00000000 --> |
<!-- Field: Doc-Info; Name: Misc; Value: 96Mps7xRiXgen8uDanwsWaSNmbP9z5Z8uekhvWBwbZl6Hygpn/SjSiXEj4umYTQL --> |
<schema xmlns="http://www.w3.org/2001/XMLSchema" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:dei="http://xbrl.sec.gov/dei/2022" xmlns:us-gaap="http://fasb.org/us-gaap/2022" xmlns:srt="http://fasb.org/srt/2022" xmlns:srt-types="http://fasb.org/srt-types/2022" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2020-01-21" xmlns:BRTX="http://biorestorative.com/20220630" elementFormDefault="qualified" targetNamespace="http://biorestorative.com/20220630"> |
| <annotation> |
| | <appinfo> |
| | | <link:roleType roleURI="http://biorestorative.com/role/Cover" id="Cover"> |
| <link:definition> 00000001 - Document - Cover </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/BalanceSheets" id="BalanceSheets"> |
| <link:definition> 00000002 - Statement - Condensed Consolidated Balance Sheets </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/BalanceSheetsParenthetical" id="BalanceSheetsParenthetical"> |
| <link:definition> 00000003 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/StatementsOfOperations" id="StatementsOfOperations"> |
| <link:definition> 00000004 - Statement - Condensed Consolidated Statements of Operations (Unaudited) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/StatementsOfChangesInStockholdersEquityDeficit" id="StatementsOfChangesInStockholdersEquityDeficit"> |
| <link:definition> 00000005 - Statement - Condensed Consolidated Statements of Changes in Stockholders' Equity (Deficit) (Unaudited) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/StatementsOfCashFlows" id="StatementsOfCashFlows"> |
| <link:definition> 00000006 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/NatureOfOrganizationLiquidityAndBusiness" id="NatureOfOrganizationLiquidityAndBusiness"> |
| <link:definition> 00000007 - Disclosure - NATURE OF THE ORGANIZATION, LIQUIDITY, AND BUSINESS </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/SummaryOfSignificantAccountingPolicies" id="SummaryOfSignificantAccountingPolicies"> |
| <link:definition> 00000008 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/IntangibleAssets" id="IntangibleAssets"> |
| <link:definition> 00000009 - Disclosure - INTANGIBLE ASSETS </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/AccruedExpensesAndOtherCurrentLiabilities" id="AccruedExpensesAndOtherCurrentLiabilities"> |
| <link:definition> 00000010 - Disclosure - ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/NotesPayable" id="NotesPayable"> |
| <link:definition> 00000011 - Disclosure - NOTES PAYABLE </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/StockholdersEquityDeficit" id="StockholdersEquityDeficit"> |
| <link:definition> 00000012 - Disclosure - STOCKHOLDERS’ EQUITY (DEFICIT) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/CommitmentsAndContingencies" id="CommitmentsAndContingencies"> |
| <link:definition> 00000013 - Disclosure - COMMITMENTS AND CONTINGENCIES </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/Leases" id="Leases"> |
| <link:definition> 00000014 - Disclosure - LEASES </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/SubsequentEvents" id="SubsequentEvents"> |
| <link:definition> 00000015 - Disclosure - SUBSEQUENT EVENTS </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/SummaryOfSignificantAccountingPoliciesPolicies" id="SummaryOfSignificantAccountingPoliciesPolicies"> |
| <link:definition> 00000016 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/SummaryOfSignificantAccountingPoliciesTables" id="SummaryOfSignificantAccountingPoliciesTables"> |
| <link:definition> 00000017 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/IntangibleAssetsTables" id="IntangibleAssetsTables"> |
| <link:definition> 00000018 - Disclosure - INTANGIBLE ASSETS (Tables) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/AccruedExpensesAndOtherCurrentLiabilitiesTables" id="AccruedExpensesAndOtherCurrentLiabilitiesTables"> |
| <link:definition> 00000019 - Disclosure - ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Tables) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/NotesPayableTables" id="NotesPayableTables"> |
| <link:definition> 00000020 - Disclosure - NOTES PAYABLE (Tables) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/StockholdersEquityDeficitTables" id="StockholdersEquityDeficitTables"> |
| <link:definition> 00000021 - Disclosure - STOCKHOLDERS’ EQUITY (DEFICIT) (Tables) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/LeasesTables" id="LeasesTables"> |
| <link:definition> 00000022 - Disclosure - LEASES (Tables) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/NatureOfOrganizationLiquidityAndBusinessDetailsNarrative" id="NatureOfOrganizationLiquidityAndBusinessDetailsNarrative"> |
| <link:definition> 00000023 - Disclosure - NATURE OF THE ORGANIZATION, LIQUIDITY, AND BUSINESS (Details Narrative) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfWeightedAverageDilutiveCommonSharesDetails" id="ScheduleOfWeightedAverageDilutiveCommonSharesDetails"> |
| <link:definition> 00000024 - Disclosure - SCHEDULE OF WEIGHTED AVERAGE DILUTIVE COMMON SHARES (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfWeightedAverageDilutiveCommonSharesDetailsParenthetical" id="ScheduleOfWeightedAverageDilutiveCommonSharesDetailsParenthetical"> |
| <link:definition> 00000025 - Disclosure - SCHEDULE OF WEIGHTED AVERAGE DILUTIVE COMMON SHARES (Details) (Parenthetical) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/SummaryOfSignificantAccountingPoliciesDetailsNarrative" id="SummaryOfSignificantAccountingPoliciesDetailsNarrative"> |
| <link:definition> 00000026 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfFiniteLivedIntangibleAssetsDetails" id="ScheduleOfFiniteLivedIntangibleAssetsDetails"> |
| <link:definition> 00000027 - Disclosure - SCHEDULE OF FINITE LIVED INTANGIBLE ASSETS (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfFiniteLivedIntangibleAssetsAmortizationExpensesDetails" id="ScheduleOfFiniteLivedIntangibleAssetsAmortizationExpensesDetails"> |
| <link:definition> 00000028 - Disclosure - SCHEDULE OF FINITE LIVED INTANGIBLE ASSETS AMORTIZATION EXPENSES (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfAccruedExpensesAndOtherCurrentLiabilitiesDetails" id="ScheduleOfAccruedExpensesAndOtherCurrentLiabilitiesDetails"> |
| <link:definition> 00000029 - Disclosure - SCHEDULE OF ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfNotesPayableActivityDetails" id="ScheduleOfNotesPayableActivityDetails"> |
| <link:definition> 00000030 - Disclosure - SCHEDULE OF NOTES PAYABLE ACTIVITY (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/NotesPayableDetailsNarrative" id="NotesPayableDetailsNarrative"> |
| <link:definition> 00000031 - Disclosure - NOTES PAYABLE (Details Narrative) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfWarrantActivityDetails" id="ScheduleOfWarrantActivityDetails"> |
| <link:definition> 00000032 - Disclosure - SCHEDULE OF WARRANT ACTIVITY (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfStockWarrantsDetails" id="ScheduleOfStockWarrantsDetails"> |
| <link:definition> 00000033 - Disclosure - SCHEDULE OF STOCK WARRANTS (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfStockOptionGrantedAssumptionsDetails" id="ScheduleOfStockOptionGrantedAssumptionsDetails"> |
| <link:definition> 00000034 - Disclosure - SCHEDULE OF STOCK OPTION GRANTED ASSUMPTIONS (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfStockOptionActivityDetails" id="ScheduleOfStockOptionActivityDetails"> |
| <link:definition> 00000035 - Disclosure - SCHEDULE OF STOCK OPTION ACTIVITY (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfStockOptionByExercisePriceDetails" id="ScheduleOfStockOptionByExercisePriceDetails"> |
| <link:definition> 00000036 - Disclosure - SCHEDULE OF STOCK OPTION BY EXERCISE PRICE (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfStockOptionByExercisePriceDetailsParenthetical" id="ScheduleOfStockOptionByExercisePriceDetailsParenthetical"> |
| <link:definition> 00000037 - Disclosure - SCHEDULE OF STOCK OPTION BY EXERCISE PRICE (Details) (Parenthetical) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfUnvestedRestrictedStockUnitsDetails" id="ScheduleOfUnvestedRestrictedStockUnitsDetails"> |
| <link:definition> 00000038 - Disclosure - SCHEDULE OF UNVESTED RESTRICTED STOCK UNITS (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfStockCompensationExpenseDetails" id="ScheduleOfStockCompensationExpenseDetails"> |
| <link:definition> 00000039 - Disclosure - SCHEDULE OF STOCK COMPENSATION EXPENSE (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/StockholdersEquityDeficitDetailsNarrative" id="StockholdersEquityDeficitDetailsNarrative"> |
| <link:definition> 00000040 - Disclosure - STOCKHOLDERS’ EQUITY (DEFICIT) (Details Narrative) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/CommitmentsAndContingenciesDetailsNarrative" id="CommitmentsAndContingenciesDetailsNarrative"> |
| <link:definition> 00000041 - Disclosure - COMMITMENTS AND CONTINGENCIES (Details Narrative) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfNetLeaseCostAndOtherSupplementalLeaseInformationDetails" id="ScheduleOfNetLeaseCostAndOtherSupplementalLeaseInformationDetails"> |
| <link:definition> 00000042 - Disclosure - SCHEDULE OF NET LEASE COST AND OTHER SUPPLEMENTAL LEASE INFORMATION (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/ScheduleOfFutureMinimumPaymentsUnderNon-cancelableLeasesForOperatingLeasesDetails" id="ScheduleOfFutureMinimumPaymentsUnderNon-cancelableLeasesForOperatingLeasesDetails"> |
| <link:definition> 00000043 - Disclosure - SCHEDULE OF FUTURE MINIMUM PAYMENTS UNDER NON-CANCELABLE LEASES FOR OPERATING LEASES (Details) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/LeasesDetailsNarrative" id="LeasesDetailsNarrative"> |
| <link:definition> 00000044 - Disclosure - LEASES (Details Narrative) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:roleType roleURI="http://biorestorative.com/role/SubsequentEventsDetailsNarrative" id="SubsequentEventsDetailsNarrative"> |
| <link:definition> 00000045 - Disclosure - SUBSEQUENT EVENTS (Details Narrative) </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
| | | <link:linkbaseRef xlink:type="simple" xlink:href="brtx-20220630_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Presentation Links"/> |
| | | <link:linkbaseRef xlink:type="simple" xlink:href="brtx-20220630_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Label Links"/> |
| | | <link:linkbaseRef xlink:type="simple" xlink:href="brtx-20220630_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Calculation Links"/> |
| | | <link:linkbaseRef xlink:type="simple" xlink:href="brtx-20220630_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Definition Links"/> |
| | | </appinfo> |
| | </annotation> |
| <import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/> |
| <import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/> |
| <import namespace="http://xbrl.sec.gov/dei/2022" schemaLocation="https://xbrl.sec.gov/dei/2022/dei-2022.xsd"/> |
| <import namespace="http://fasb.org/us-gaap/2022" schemaLocation="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd"/> |
| <import namespace="http://fasb.org/us-types/2022" schemaLocation="https://xbrl.fasb.org/us-gaap/2022/elts/us-types-2022.xsd"/> |
| <import namespace="http://www.xbrl.org/dtr/type/2020-01-21" schemaLocation="https://www.xbrl.org/dtr/type/2020-01-21/types.xsd"/> |
| <import namespace="http://xbrl.sec.gov/country/2022" schemaLocation="https://xbrl.sec.gov/country/2022/country-2022.xsd"/> |
| <import namespace="http://fasb.org/srt/2022" schemaLocation="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd"/> |
| <import namespace="http://fasb.org/srt-types/2022" schemaLocation="https://xbrl.fasb.org/srt/2022/elts/srt-types-2022.xsd"/> |
| <element id="BRTX_SeriesAConvertiblePreferredStockMember" name="SeriesAConvertiblePreferredStockMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_OptionsMember" name="OptionsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_UnvestedRSUsMember" name="UnvestedRSUsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ConvertibleNotesCommonStockMember" name="ConvertibleNotesCommonStockMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_PatentsAndTrademarksMember" name="PatentsAndTrademarksMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_LicensesMember" name="LicensesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_AccumulatedAmortizationMember" name="AccumulatedAmortizationMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_PPPLoanMember" name="PPPLoanMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_PaycheckProtectionProgramMember" name="PaycheckProtectionProgramMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_BoardOfDirectorsMember" name="BoardOfDirectorsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_TwoThousandTwentyOneStockIncentivePlanMember" name="TwoThousandTwentyOneStockIncentivePlanMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_TwoEmploymentAgreementsMember" name="TwoEmploymentAgreementsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ChiefExecutiveOfficerAndChairmanOfTheBoardAndVicePresidentMember" name="ChiefExecutiveOfficerAndChairmanOfTheBoardAndVicePresidentMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceOneMember" name="ExercisePriceOneMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceTwoMember" name="ExercisePriceTwoMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceThreeMember" name="ExercisePriceThreeMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceFourMember" name="ExercisePriceFourMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceFiveMember" name="ExercisePriceFiveMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceSixMember" name="ExercisePriceSixMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceSevenMember" name="ExercisePriceSevenMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceEightMember" name="ExercisePriceEightMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceNineMember" name="ExercisePriceNineMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceTenMember" name="ExercisePriceTenMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ExercisePriceElevenMember" name="ExercisePriceElevenMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ConsultingExpensesMember" name="ConsultingExpensesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ClinicalServicesAgreementMember" name="ClinicalServicesAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ProfessionalResearchConsultingIncMember" name="ProfessionalResearchConsultingIncMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_MelvilleLeaseMember" name="MelvilleLeaseMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_LanceAlstodtMember" name="LanceAlstodtMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_FranciscoSilvaMember" name="FranciscoSilvaMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_GainOnPppLoanForgiveness" name="GainOnPppLoanForgiveness" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_GrantIncome" name="GrantIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_SharesIssuedInCashlessExerciseOfWarrants" name="SharesIssuedInCashlessExerciseOfWarrants" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_SharesIssuedInCashlessExerciseOfWarrantsShares" name="SharesIssuedInCashlessExerciseOfWarrantsShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationOptions" name="ShareBasedCompensationOptions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationRestrictedStockAward" name="ShareBasedCompensationRestrictedStockAward" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_NoncashLeaseExpense" name="NoncashLeaseExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ProceedsFromPppLoan" name="ProceedsFromPppLoan" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_DisclosureLeasesAbstract" name="DisclosureLeasesAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ContractModificationsPolicyTextBlock" name="ContractModificationsPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_GrandIncomePolicyTextBlock" name="GrandIncomePolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ScheduleOfShareBasedCompensationWarrantOutstandingAndExercisableByExercisePriceRangeTableTextBlock" name="ScheduleOfShareBasedCompensationWarrantOutstandingAndExercisableByExercisePriceRangeTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_SecuritiesPursuantAggregateShares" name="SecuritiesPursuantAggregateShares" nillable="true" xbrli:periodType="instant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_WorkingCapitalSurplus" name="WorkingCapitalSurplus" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_AccruedResearchAndDevelopmentExpenses" name="AccruedResearchAndDevelopmentExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_AccruedGeneralAndAdministrativeExpenses" name="AccruedGeneralAndAdministrativeExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionsOutstandingWeightedAverageExercisePrice" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionsOutstandingWeightedAverageExercisePrice" nillable="true" xbrli:periodType="instant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationArrangementsByShareBasedPaymentAwardNonOptionsGrantsInPeriodWeightedAverageExercisePrice" name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardNonOptionsGrantsInPeriodWeightedAverageExercisePrice" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationArrangementsByShareBasedPaymentAwardNonOptionsExercisedInPeriodWeightedAverageExercisePrice" name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardNonOptionsExercisedInPeriodWeightedAverageExercisePrice" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationArrangementsByShareBasedPaymentAwardNonOptionsExpiredInPeriodWeightedAverageExercisePrice" name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardNonOptionsExpiredInPeriodWeightedAverageExercisePrice" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionsExercisableWeightedAverageExercisePrice" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionsExercisableWeightedAverageExercisePrice" nillable="true" xbrli:periodType="instant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_SharebasedCompensationArrangementBySharebasedPaymentAwardNonOptionsExercisableWeightedAverageRemainingContractualTerm1" name="SharebasedCompensationArrangementBySharebasedPaymentAwardNonOptionsExercisableWeightedAverageRemainingContractualTerm1" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_UnamortizedCompensationExpense" name="UnamortizedCompensationExpense" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_ServicesAgreementTerm" name="ServicesAgreementTerm" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item"/> |
| <element id="BRTX_OperatingLeaseLiabilityReduction" name="OperatingLeaseLiabilityReduction" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/> |
| </schema> |