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Advaxis, Inc. – ‘10-Q’ for 4/30/22 – ‘EX-101.SCH’

On:  Tuesday, 6/7/22, at 8:41pm ET   ·   As of:  6/8/22   ·   For:  4/30/22   ·   Accession #:  1493152-22-16125   ·   File #:  1-36138

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  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 6/08/22  Advaxis, Inc.                     10-Q        4/30/22   73:4.7M                                   M2 Compliance LLC/FA

Quarterly Report   —   Form 10-Q

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-Q        Quarterly Report                                    HTML    761K 
 2: EX-31.1     Certification -- §302 - SOA'02                      HTML     27K 
 3: EX-31.2     Certification -- §302 - SOA'02                      HTML     27K 
 4: EX-32.1     Certification -- §906 - SOA'02                      HTML     22K 
 5: EX-32.2     Certification -- §906 - SOA'02                      HTML     22K 
11: R1          Cover                                               HTML     74K 
12: R2          Condensed Consolidated Balance Sheets               HTML    109K 
13: R3          Condensed Consolidated Balance Sheets               HTML     51K 
                (Parenthetical)                                                  
14: R4          Condensed Consolidated Statements of Operations     HTML     85K 
                (Unaudited)                                                      
15: R5          Condensed Consolidated Statements of Cash Flows     HTML    108K 
                (Unaudited)                                                      
16: R6          Nature of Operations                                HTML     32K 
17: R7          Summary of Significant Accounting Policies and      HTML     47K 
                Basis of Presentation                                            
18: R8          Property and Equipment                              HTML     32K 
19: R9          Intangible Assets                                   HTML     41K 
20: R10         Accrued Expenses                                    HTML     28K 
21: R11         Leases                                              HTML     54K 
22: R12         Common Stock Purchase Warrants and Warrant          HTML     80K 
                Liability                                                        
23: R13         Commitments and Contingencies                       HTML     30K 
24: R14         Temporary Equity                                    HTML     43K 
25: R15         Stockholders? Equity                                HTML     75K 
26: R16         Share Based Compensation                            HTML     74K 
27: R17         Licensing Agreements                                HTML     30K 
28: R18         Fair Value                                          HTML     60K 
29: R19         Summary of Significant Accounting Policies and      HTML     61K 
                Basis of Presentation (Policies)                                 
30: R20         Summary of Significant Accounting Policies and      HTML     28K 
                Basis of Presentation (Tables)                                   
31: R21         Property and Equipment (Tables)                     HTML     28K 
32: R22         Intangible Assets (Tables)                          HTML     36K 
33: R23         Accrued Expenses (Tables)                           HTML     28K 
34: R24         Leases (Tables)                                     HTML     55K 
35: R25         Common Stock Purchase Warrants and Warrant          HTML     67K 
                Liability (Tables)                                               
36: R26         Temporary Equity (Tables)                           HTML     28K 
37: R27         Stockholders? Equity (Tables)                       HTML     70K 
38: R28         Share Based Compensation (Tables)                   HTML     74K 
39: R29         Fair Value (Tables)                                 HTML     59K 
40: R30         Nature of Operations (Details Narrative)            HTML     24K 
41: R31         Schedule of Anti -Diluted Securities Excluded From  HTML     28K 
                Diluted Net Loss Per Share (Details)                             
42: R32         Summary of Significant Accounting Policies and      HTML     28K 
                Basis of Presentation (Details Narrative)                        
43: R33         Schedule of Property and Equipment (Details)        HTML     33K 
44: R34         Property and Equipment (Details Narrative)          HTML     31K 
45: R35         Summary of Intangible Assets (Details)              HTML     34K 
46: R36         Schedule of Carrying Value of Intangible Assets     HTML     36K 
                (Details)                                                        
47: R37         Intangible Assets (Details Narrative)               HTML     29K 
48: R38         Summary of Accrued Expenses (Details)               HTML     32K 
49: R39         Schedule of Supplemental Balance Sheet Related to   HTML     29K 
                Leases (Details)                                                 
50: R40         Schedule of Lease Expenses (Details)                HTML     30K 
51: R41         Schedule of Other Information Related to Leases     HTML     25K 
                (Details)                                                        
52: R42         Schedule of Cash Flow Information Related to        HTML     23K 
                Leases (Details)                                                 
53: R43         Schedule of Future Minimum Lease Payments Under     HTML     32K 
                Non-Cancellable Leases (Details)                                 
54: R44         Leases (Details Narrative)                          HTML     39K 
55: R45         Schedule of Common Stock Purchase Warrants and      HTML     45K 
                Warrant Liability (Details)                                      
56: R46         Schedule of Assumptions Used in Warrant Liability   HTML     39K 
                (Details)                                                        
57: R47         Common Stock Purchase Warrants and Warrant          HTML     55K 
                Liability (Details Narrative)                                    
58: R48         Schedule of Preferred Stock Redemption Liability    HTML     31K 
                (Details)                                                        
59: R49         Temporary Equity (Details Narrative)                HTML     62K 
60: R50         Summary of Stockholders Equity (Details)            HTML     99K 
61: R51         Summary of Share Based Compensation Expense         HTML     28K 
                (Details)                                                        
62: R52         Summary of Changes in Stock Option Plan (Details)   HTML     48K 
63: R53         Summary of Outstanding and Exercisable Options      HTML     57K 
                (Details)                                                        
64: R54         Share Based Compensation (Details Narrative)        HTML     30K 
65: R55         Licensing Agreements (Details Narrative)            HTML     39K 
66: R56         Schedule of Fair Value, Assets and Liabilities      HTML     56K 
                Measured on Recurring Basis (Details)                            
67: R57         Schedule of Fair Value, Assets and Liabilities      HTML     25K 
                Measured on Recurring Basis (Details)                            
                (Parenthetical)                                                  
68: R58         Schedule of Fair Value Measuring Unobservable       HTML     38K 
                Inputs (Details)                                                 
71: XML         IDEA XML File -- Filing Summary                      XML    129K 
69: XML         XBRL Instance -- form10-q_htm                        XML   1.15M 
70: EXCEL       IDEA Workbook of Financial Reports                  XLSX     77K 
 7: EX-101.CAL  Inline XBRL Taxonomy Extension Calculation           XML    167K 
                Linkbase Document -- adxs-20220430_cal                           
 8: EX-101.DEF  Inline XBRL Taxonomy Extension Definition Linkbase   XML    377K 
                Document -- adxs-20220430_def                                    
 9: EX-101.LAB  Inline XBRL Taxonomy Extension Label Linkbase        XML    811K 
                Document -- adxs-20220430_lab                                    
10: EX-101.PRE  Inline XBRL Taxonomy Extension Presentation          XML    636K 
                Linkbase Document -- adxs-20220430_pre                           
 6: EX-101.SCH  Inline XBRL Taxonomy Extension Schema Document --    XSD    131K 
                adxs-20220430                                                    
72: JSON        XBRL Instance as JSON Data -- MetaLinks              291±   404K 
73: ZIP         XBRL Zipped Folder -- 0001493152-22-016125-xbrl      Zip    139K

‘EX-101.SCH’   —   Inline XBRL Taxonomy Extension Schema Document — adxs-20220430

This Exhibit is an XBRL XML File.

                                                                                                                                                                                
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<link:definition> 00000010 - Disclosure - ACCRUED EXPENSES </link:definition>
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<link:roleType roleURI="http://advaxis.com/role/StockholdersEquity" id="StockholdersEquity">
<link:definition> 00000015 - Disclosure - STOCKHOLDERS’ EQUITY </link:definition>
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<link:usedOn> link:calculationLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/ShareBasedCompensation" id="ShareBasedCompensation">
<link:definition> 00000016 - Disclosure - SHARE BASED COMPENSATION </link:definition>
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<link:usedOn> link:calculationLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/LicensingAgreements" id="LicensingAgreements">
<link:definition> 00000017 - Disclosure - LICENSING AGREEMENTS </link:definition>
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<link:definition> 00000018 - Disclosure - FAIR VALUE </link:definition>
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<link:roleType roleURI="http://advaxis.com/role/PropertyAndEquipmentTables" id="PropertyAndEquipmentTables">
<link:definition> 00000021 - Disclosure - PROPERTY AND EQUIPMENT (Tables) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/IntangibleAssetsTables" id="IntangibleAssetsTables">
<link:definition> 00000022 - Disclosure - INTANGIBLE ASSETS (Tables) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/AccruedExpensesTables" id="AccruedExpensesTables">
<link:definition> 00000023 - Disclosure - ACCRUED EXPENSES (Tables) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/LeasesTables" id="LeasesTables">
<link:definition> 00000024 - Disclosure - LEASES (Tables) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/TemporaryEquityTables" id="TemporaryEquityTables">
<link:definition> 00000026 - Disclosure - TEMPORARY EQUITY (Tables) </link:definition>
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<link:definition> 00000027 - Disclosure - STOCKHOLDERS’ EQUITY (Tables) </link:definition>
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<link:definition> 00000028 - Disclosure - SHARE BASED COMPENSATION (Tables) </link:definition>
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<link:roleType roleURI="http://advaxis.com/role/FairValueTables" id="FairValueTables">
<link:definition> 00000029 - Disclosure - FAIR VALUE (Tables) </link:definition>
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<link:definition> 00000038 - Disclosure - SUMMARY OF ACCRUED EXPENSES (Details) </link:definition>
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<link:definition> 00000039 - Disclosure - SCHEDULE OF SUPPLEMENTAL BALANCE SHEET RELATED TO LEASES (Details) </link:definition>
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<link:roleType roleURI="http://advaxis.com/role/ScheduleOfLeaseExpensesDetails" id="ScheduleOfLeaseExpensesDetails">
<link:definition> 00000040 - Disclosure - SCHEDULE OF LEASE EXPENSES (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/ScheduleOfOtherInformationRelatedToLeasesDetails" id="ScheduleOfOtherInformationRelatedToLeasesDetails">
<link:definition> 00000041 - Disclosure - SCHEDULE OF OTHER INFORMATION RELATED TO LEASES (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
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<link:roleType roleURI="http://advaxis.com/role/ScheduleOfCashFlowInformationRelatedToLeasesDetails" id="ScheduleOfCashFlowInformationRelatedToLeasesDetails">
<link:definition> 00000042 - Disclosure - SCHEDULE OF CASH FLOW INFORMATION RELATED TO LEASES (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ScheduleOfFutureMinimumLeasePaymentsUnderNon-cancellableLeasesDetails" id="ScheduleOfFutureMinimumLeasePaymentsUnderNon-cancellableLeasesDetails">
<link:definition> 00000043 - Disclosure - SCHEDULE OF FUTURE MINIMUM LEASE PAYMENTS UNDER NON-CANCELLABLE LEASES (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/LeasesDetailsNarrative" id="LeasesDetailsNarrative">
<link:definition> 00000044 - Disclosure - LEASES (Details Narrative) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ScheduleOfCommonStockPurchaseWarrantsAndWarrantLiabilityDetails" id="ScheduleOfCommonStockPurchaseWarrantsAndWarrantLiabilityDetails">
<link:definition> 00000045 - Disclosure - SCHEDULE OF COMMON STOCK PURCHASE WARRANTS AND WARRANT LIABILITY (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ScheduleOfAssumptionsUsedInWarrantLiabilityDetails" id="ScheduleOfAssumptionsUsedInWarrantLiabilityDetails">
<link:definition> 00000046 - Disclosure - SCHEDULE OF ASSUMPTIONS USED IN WARRANT LIABILITY (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/CommonStockPurchaseWarrantsAndWarrantLiabilityDetailsNarrative" id="CommonStockPurchaseWarrantsAndWarrantLiabilityDetailsNarrative">
<link:definition> 00000047 - Disclosure - COMMON STOCK PURCHASE WARRANTS AND WARRANT LIABILITY (Details Narrative) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ScheduleOfPreferredStockRedemptionLiabilityDetails" id="ScheduleOfPreferredStockRedemptionLiabilityDetails">
<link:definition> 00000048 - Disclosure - SCHEDULE OF PREFERRED STOCK REDEMPTION LIABILITY (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/TemporaryEquityDetailsNarrative" id="TemporaryEquityDetailsNarrative">
<link:definition> 00000049 - Disclosure - TEMPORARY EQUITY (Details Narrative) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/SummaryOfStockholdersEquityDetails" id="SummaryOfStockholdersEquityDetails">
<link:definition> 00000050 - Disclosure - SUMMARY OF STOCKHOLDERS EQUITY (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/SummaryOfShareBasedCompensationExpenseDetails" id="SummaryOfShareBasedCompensationExpenseDetails">
<link:definition> 00000051 - Disclosure - SUMMARY OF SHARE BASED COMPENSATION EXPENSE (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/SummaryOfChangesInStockOptionPlanDetails" id="SummaryOfChangesInStockOptionPlanDetails">
<link:definition> 00000052 - Disclosure - SUMMARY OF CHANGES IN STOCK OPTION PLAN (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/SummaryOfOutstandingAndExercisableOptionsDetails" id="SummaryOfOutstandingAndExercisableOptionsDetails">
<link:definition> 00000053 - Disclosure - SUMMARY OF OUTSTANDING AND EXERCISABLE OPTIONS (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ShareBasedCompensationDetailsNarrative" id="ShareBasedCompensationDetailsNarrative">
<link:definition> 00000054 - Disclosure - SHARE BASED COMPENSATION (Details Narrative) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/LicensingAgreementsDetailsNarrative" id="LicensingAgreementsDetailsNarrative">
<link:definition> 00000055 - Disclosure - LICENSING AGREEMENTS (Details Narrative) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisDetails" id="ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisDetails">
<link:definition> 00000056 - Disclosure - SCHEDULE OF FAIR VALUE, ASSETS AND LIABILITIES MEASURED ON RECURRING BASIS (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisDetailsParenthetical" id="ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisDetailsParenthetical">
<link:definition> 00000057 - Disclosure - SCHEDULE OF FAIR VALUE, ASSETS AND LIABILITIES MEASURED ON RECURRING BASIS (Details) (Parenthetical) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:roleType roleURI="http://advaxis.com/role/ScheduleOfFairValueMeasuringUnobservableInputsDetails" id="ScheduleOfFairValueMeasuringUnobservableInputsDetails">
<link:definition> 00000058 - Disclosure - SCHEDULE OF FAIR VALUE MEASURING UNOBSERVABLE INPUTS (Details) </link:definition>
<link:usedOn> link:presentationLink </link:usedOn>
<link:usedOn> link:calculationLink </link:usedOn>
<link:usedOn> link:definitionLink </link:usedOn>
</link:roleType>
<link:linkbaseRef xlink:type="simple" xlink:href="adxs-20220430_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Presentation Links"/>
<link:linkbaseRef xlink:type="simple" xlink:href="adxs-20220430_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Label Links"/>
<link:linkbaseRef xlink:type="simple" xlink:href="adxs-20220430_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Calculation Links"/>
<link:linkbaseRef xlink:type="simple" xlink:href="adxs-20220430_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:title="Definition Links"/>
</appinfo>
</annotation>
<import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/>
<import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/>
<import namespace="http://xbrl.sec.gov/dei/2022" schemaLocation="https://xbrl.sec.gov/dei/2022/dei-2022.xsd"/>
<import namespace="http://fasb.org/us-gaap/2022" schemaLocation="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd"/>
<import namespace="http://fasb.org/us-types/2022" schemaLocation="https://xbrl.fasb.org/us-gaap/2022/elts/us-types-2022.xsd"/>
<import namespace="http://www.xbrl.org/dtr/type/2020-01-21" schemaLocation="https://www.xbrl.org/dtr/type/2020-01-21/types.xsd"/>
<import namespace="http://xbrl.sec.gov/country/2022" schemaLocation="https://xbrl.sec.gov/country/2022/country-2022.xsd"/>
<import namespace="http://fasb.org/srt/2022" schemaLocation="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd"/>
<import namespace="http://fasb.org/srt-types/2022" schemaLocation="https://xbrl.fasb.org/srt/2022/elts/srt-types-2022.xsd"/>
<element id="ADXS_SeriesDConvertibleRedeemablePreferredStockMember" name="SeriesDConvertibleRedeemablePreferredStockMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_SeriesDPreferredStockRedemptionMember" name="SeriesDPreferredStockRedemptionMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_BoardOfDirectorsMember" name="BoardOfDirectorsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_StockOptionsMember" name="StockOptionsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ResearchAndDevelopmentMember" name="ResearchAndDevelopmentMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_EquityWarrantsMember" name="EquityWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_WarrantLiabilityMember" name="WarrantLiabilityMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ExercisePriceRangeOneMember" name="ExercisePriceRangeOneMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ExercisePriceRangeTwoMember" name="ExercisePriceRangeTwoMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ExercisePriceRangeThreeMember" name="ExercisePriceRangeThreeMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ExercisePriceRangeFourMember" name="ExercisePriceRangeFourMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ExercisePriceRangeFiveMember" name="ExercisePriceRangeFiveMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_InstitutionalInvestorsMember" name="InstitutionalInvestorsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_SeriesDConvertiblePreferredStockMember" name="SeriesDConvertiblePreferredStockMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_DevelopmentLicenseAndSupplyAgreementMember" name="DevelopmentLicenseAndSupplyAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_OSTherapiesMember" name="OSTherapiesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_GlobalBioPharmaIncMember" name="GlobalBioPharmaIncMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ThroughSeptemberTwoThousandTwentyFourMember" name="ThroughSeptemberTwoThousandTwentyFourMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_PreferredStockRedemptionLiabilityMember" name="PreferredStockRedemptionLiabilityMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_CommonStockWarrantLiability" name="CommonStockWarrantLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_GainOnChangeInValueOfWarrants" name="GainOnChangeInValueOfWarrants" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_GainOnChangeInValueOfPreferredStockRedemptionLiability" name="GainOnChangeInValueOfPreferredStockRedemptionLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_LossOnSaleOfPropertyPlantEquipment" name="LossOnSaleOfPropertyPlantEquipment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_NetGainOnWriteOffOfRightofuseAssetAndLeaseLiability" name="NetGainOnWriteOffOfRightofuseAssetAndLeaseLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_IncreaseDecreaseInOperatingLeaseLiabilities" name="IncreaseDecreaseInOperatingLeaseLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_RedemptionOfSeriesDPreferredStock" name="RedemptionOfSeriesDPreferredStock" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_AccretionOfDiscountAndRedemptionFeatureOfConvertiblePreferredStock" name="AccretionOfDiscountAndRedemptionFeatureOfConvertiblePreferredStock" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_DisclosureLeasesAbstract" name="DisclosureLeasesAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_DisclosureCommonStockPurchaseWarrantsAndWarrantLiabilityAbstract" name="DisclosureCommonStockPurchaseWarrantsAndWarrantLiabilityAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_CommonStockPurchaseWarrantsAndWarrantLiabilityTextBlock" name="CommonStockPurchaseWarrantsAndWarrantLiabilityTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_DisclosureTemporaryEquityAbstract" name="DisclosureTemporaryEquityAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_TemporaryEquityDisclosureTextBlock" name="TemporaryEquityDisclosureTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_DisclosureLicensingAgreementsAbstract" name="DisclosureLicensingAgreementsAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_LicensingAgreementsDisclosuresTextBlock" name="LicensingAgreementsDisclosuresTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ConvertablePreferredStockPolicyTextBlock" name="ConvertablePreferredStockPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ReverseStockSplitPolicyTextBlock" name="ReverseStockSplitPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ScheduleOfSupplementalBalanceSheetInformationRelatedToLeasesTableTextBlock" name="ScheduleOfSupplementalBalanceSheetInformationRelatedToLeasesTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ScheduleOfOtherInformationTableTextBlock" name="ScheduleOfOtherInformationTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ScheduleOfOutstandingWarrantsTableTextBlock" name="ScheduleOfOutstandingWarrantsTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_PreferredStockRedemptionLiabilityTableTextBlock" name="PreferredStockRedemptionLiabilityTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_FiniteLivedSoftwareGross" name="FiniteLivedSoftwareGross" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_PaymentOfRent" name="PaymentOfRent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_LesseeFinanceLeasesRenewalTerm" name="LesseeFinanceLeasesRenewalTerm" nillable="true" xbrli:periodType="duration" type="xbrli:dateItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_WarrantsExpirationDescription" name="WarrantsExpirationDescription" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ClassOfWarrantOrRightTitleOfSecurityWarrantsOrRightsOutstandings" name="ClassOfWarrantOrRightTitleOfSecurityWarrantsOrRightsOutstandings" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_FairValueOfWarrantLiability" name="FairValueOfWarrantLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_PreferredStockDiscountRatePercentage" name="PreferredStockDiscountRatePercentage" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_TemporaryEquityStockStatedValueAccumulatedDividends" name="TemporaryEquityStockStatedValueAccumulatedDividends" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_TemporaryEquityStockStatedValueAccumulatedDividendsOnExtension" name="TemporaryEquityStockStatedValueAccumulatedDividendsOnExtension" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_ProceedsFromIssuanceOrEstimatedOffering" name="ProceedsFromIssuanceOrEstimatedOffering" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_StockIssuedDuringPeriodValueWarrantsExercised" name="StockIssuedDuringPeriodValueWarrantsExercised" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_StockIssuedDuringPeriodSharesWarrantsExercised" name="StockIssuedDuringPeriodSharesWarrantsExercised" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_StockIssuedDuringPeriodValueEmployeesUnderESPPPlan" name="StockIssuedDuringPeriodValueEmployeesUnderESPPPlan" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_StockIssuedDuringPeriodSharesEmployeesUnderESPPPlan" name="StockIssuedDuringPeriodSharesEmployeesUnderESPPPlan" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_StockIssuedDuringPeriodValueAccretionOfDiscountAndRedemptionFeatureOfConvertiblePreferredStock" name="StockIssuedDuringPeriodValueAccretionOfDiscountAndRedemptionFeatureOfConvertiblePreferredStock" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_StockIssuedDuringPeriodValueConvertiblePreferredStockRedemption" name="StockIssuedDuringPeriodValueConvertiblePreferredStockRedemption" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermEnding" name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermEnding" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_FundingMilestonePayment" name="FundingMilestonePayment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_MilestoneAchievementDescription" name="MilestoneAchievementDescription" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_FundingForSecondMilestonePayment" name="FundingForSecondMilestonePayment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_CommonStockWarrantLiability1" name="CommonStockWarrantLiability1" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPeriodRedemption" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPeriodRedemption" nillable="true" xbrli:periodType="duration" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_PreferredStockRedemptionLiability" name="PreferredStockRedemptionLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_FinancialAdvisorsFeesAndOtherEstimatedOfferingExpenses" name="FinancialAdvisorsFeesAndOtherEstimatedOfferingExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
<element id="ADXS_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityRedemption" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityRedemption" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item"/>
</schema>

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