| | | | | | | | | | | | | | | | | | | | | |
<?xml version="1.0" standalone="yes" encoding="windows-1252"?> |
<!-- XBRL Document Created with XBRLMaster --> |
<!-- Version: 2.3.08 --> |
<!-- Based on XBRL 2.1 --> |
<!-- Date of creation: 08/12/2022 --> |
<!-- Software architectural design and coding: A'c Dharmapremananda Avt. --> |
<!-- Copyright (c) 2022 I-NET Business Solutions, Inc. All Rights Reserved. --> |
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"> |
| <link:roleRef roleURI="http://celz.com/role/Cover" xlink:href="celz-20220630.xsd#Cover" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/CondensedConsolidatedBalanceSheets" xlink:href="celz-20220630.xsd#CondensedConsolidatedBalanceSheets" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:href="celz-20220630.xsd#CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/UnauditedCondensedConsolidatedStatementsOfOperations" xlink:href="celz-20220630.xsd#UnauditedCondensedConsolidatedStatementsOfOperations" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/UnauditedCondensedConsolidatedStatementsOfCashFlows" xlink:href="celz-20220630.xsd#UnauditedCondensedConsolidatedStatementsOfCashFlows" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/UnauditedCondensedConsolidatedStatementsOfStockholdersEquityDeficit" xlink:href="celz-20220630.xsd#UnauditedCondensedConsolidatedStatementsOfStockholdersEquityDeficit" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPolicies" xlink:href="celz-20220630.xsd#OrganizationAndSummaryOfSignificantAccountingPolicies" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/LicensingAgreements" xlink:href="celz-20220630.xsd#LicensingAgreements" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/RelatedPartyTransactions" xlink:href="celz-20220630.xsd#RelatedPartyTransactions" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/DEBT" xlink:href="celz-20220630.xsd#DEBT" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/DerivativeLiabilities" xlink:href="celz-20220630.xsd#DerivativeLiabilities" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockbasedCompensation" xlink:href="celz-20220630.xsd#StockbasedCompensation" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockholdersEquity" xlink:href="celz-20220630.xsd#StockholdersEquity" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/SubsequentEvents" xlink:href="celz-20220630.xsd#SubsequentEvents" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesPolicies" xlink:href="celz-20220630.xsd#OrganizationAndSummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesTables" xlink:href="celz-20220630.xsd#OrganizationAndSummaryOfSignificantAccountingPoliciesTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/LicensingAgreementsTables" xlink:href="celz-20220630.xsd#LicensingAgreementsTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockbasedCompensationTables" xlink:href="celz-20220630.xsd#StockbasedCompensationTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockholdersEquityTables" xlink:href="celz-20220630.xsd#StockholdersEquityTables" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesDetails" xlink:href="celz-20220630.xsd#OrganizationAndSummaryOfSignificantAccountingPoliciesDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:href="celz-20220630.xsd#OrganizationAndSummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/LicensingAgreementsDetails" xlink:href="celz-20220630.xsd#LicensingAgreementsDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/LicensingAgreementsDetailsNarrative" xlink:href="celz-20220630.xsd#LicensingAgreementsDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/RelatedPartyTransactionsDetailsNarrative" xlink:href="celz-20220630.xsd#RelatedPartyTransactionsDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/DebtDetailsNarrative" xlink:href="celz-20220630.xsd#DebtDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/DerivativeLiabilitiesDetailsNarrative" xlink:href="celz-20220630.xsd#DerivativeLiabilitiesDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockbasedCompensationDetails" xlink:href="celz-20220630.xsd#StockbasedCompensationDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockbasedCompensationDetails1" xlink:href="celz-20220630.xsd#StockbasedCompensationDetails1" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockbasedCompensationDetailsNarrative" xlink:href="celz-20220630.xsd#StockbasedCompensationDetailsNarrative" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockholdersEquityDetails" xlink:href="celz-20220630.xsd#StockholdersEquityDetails" xlink:type="simple"/> |
| <link:roleRef roleURI="http://celz.com/role/StockholdersEquityDetailsNarrative" xlink:href="celz-20220630.xsd#StockholdersEquityDetailsNarrative" xlink:type="simple"/> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/Cover" xlink:title="00000001 - Document - Cover Page Information"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CoverAbstract" xlink:label="loc_deiCoverAbstract"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityRegistrantName" xlink:label="loc_deiEntityRegistrantName"/> |
| | <link:presentationArc order="0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityRegistrantName" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey" xlink:label="loc_deiEntityCentralIndexKey"/> |
| | <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityCentralIndexKey" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentType" xlink:label="loc_deiDocumentType"/> |
| | <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentType" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentFlag" xlink:label="loc_deiAmendmentFlag"/> |
| | <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiAmendmentFlag" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_deiCurrentFiscalYearEndDate"/> |
| | <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiCurrentFiscalYearEndDate" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntitySmallBusiness" xlink:label="loc_deiEntitySmallBusiness"/> |
| | <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntitySmallBusiness" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityShellCompany" xlink:label="loc_deiEntityShellCompany"/> |
| | <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityShellCompany" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_deiEntityEmergingGrowthCompany"/> |
| | <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityEmergingGrowthCompany" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_deiEntityCurrentReportingStatus"/> |
| | <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityCurrentReportingStatus" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_deiDocumentPeriodEndDate"/> |
| | <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentPeriodEndDate" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFilerCategory" xlink:label="loc_deiEntityFilerCategory"/> |
| | <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityFilerCategory" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_deiDocumentFiscalPeriodFocus"/> |
| | <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentFiscalPeriodFocus" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_deiDocumentFiscalYearFocus"/> |
| | <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentFiscalYearFocus" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_deiEntityCommonStockSharesOutstanding"/> |
| | <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityCommonStockSharesOutstanding" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentQuarterlyReport" xlink:label="loc_deiDocumentQuarterlyReport"/> |
| | <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentQuarterlyReport" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber" xlink:label="loc_deiEntityFileNumber"/> |
| | <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityFileNumber" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="loc_deiEntityIncorporationStateCountryCode"/> |
| | <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityIncorporationStateCountryCode" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityTaxIdentificationNumber" xlink:label="loc_deiEntityTaxIdentificationNumber"/> |
| | <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityTaxIdentificationNumber" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityInteractiveDataCurrent" xlink:label="loc_deiEntityInteractiveDataCurrent"/> |
| | <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityInteractiveDataCurrent" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine1" xlink:label="loc_deiEntityAddressAddressLine1"/> |
| | <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressAddressLine1" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown" xlink:label="loc_deiEntityAddressCityOrTown"/> |
| | <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressCityOrTown" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince" xlink:label="loc_deiEntityAddressStateOrProvince"/> |
| | <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressStateOrProvince" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode" xlink:label="loc_deiEntityAddressPostalZipCode"/> |
| | <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiEntityAddressPostalZipCode" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode" xlink:label="loc_deiCityAreaCode"/> |
| | <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiCityAreaCode" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LocalPhoneNumber" xlink:label="loc_deiLocalPhoneNumber"/> |
| | <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiLocalPhoneNumber" xlink:type="arc"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentTransitionReport" xlink:label="loc_deiDocumentTransitionReport"/> |
| | <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_deiCoverAbstract" xlink:to="loc_deiDocumentTransitionReport" xlink:type="arc"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/CondensedConsolidatedBalanceSheets" xlink:title="000002 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaapStatementOfFinancialPositionAbstract_2f74bd"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaapAssetsAbstract_66e5b2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract_2f74bd" xlink:to="loc_us-gaapAssetsAbstract_66e5b2" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaapAssetsCurrentAbstract_8775bc"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsAbstract_66e5b2" xlink:to="loc_us-gaapAssetsCurrentAbstract_8775bc" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Cash" xlink:label="loc_us-gaapCash_ec8597"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract_8775bc" xlink:to="loc_us-gaapCash_ec8597" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNet" xlink:label="loc_us-gaapAccountsReceivableNet_303502"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract_8775bc" xlink:to="loc_us-gaapAccountsReceivableNet_303502" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaapInventoryNet_6b74af"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract_8775bc" xlink:to="loc_us-gaapInventoryNet_6b74af" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent_d925b6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract_8775bc" xlink:to="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent_d925b6" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaapAssetsCurrent_b71fa9"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract_8775bc" xlink:to="loc_us-gaapAssetsCurrent_b71fa9" order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsNoncurrentAbstract" xlink:label="loc_us-gaapAssetsNoncurrentAbstract_85e8c7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsCurrentAbstract_8775bc" xlink:to="loc_us-gaapAssetsNoncurrentAbstract_85e8c7" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssets" xlink:label="loc_us-gaapOtherAssets_adf3e6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsNoncurrentAbstract_85e8c7" xlink:to="loc_us-gaapOtherAssets_adf3e6" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaapFiniteLivedIntangibleAssetsNet_0115fe"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsNoncurrentAbstract_85e8c7" xlink:to="loc_us-gaapFiniteLivedIntangibleAssetsNet_0115fe" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Assets" xlink:label="loc_us-gaapAssets_ef485a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsNoncurrentAbstract_85e8c7" xlink:to="loc_us-gaapAssets_ef485a" order="11" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract_657005"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAssetsNoncurrentAbstract_85e8c7" xlink:to="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract_657005" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaapLiabilitiesCurrentAbstract_f3d235"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquityAbstract_657005" xlink:to="loc_us-gaapLiabilitiesCurrentAbstract_f3d235" order="13"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaapAccountsPayableCurrent_54c679"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract_f3d235" xlink:to="loc_us-gaapAccountsPayableCurrent_54c679" order="14"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaapAccruedLiabilitiesCurrent_358055"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract_f3d235" xlink:to="loc_us-gaapAccruedLiabilitiesCurrent_358055" order="15"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ManagementFeePayable" xlink:label="loc_us-gaapManagementFeePayable_eb4658"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract_f3d235" xlink:to="loc_us-gaapManagementFeePayable_eb4658" order="16"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DueToRelatedPartiesCurrent" xlink:label="loc_us-gaapDueToRelatedPartiesCurrent_04f51e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract_f3d235" xlink:to="loc_us-gaapDueToRelatedPartiesCurrent_04f51e" order="17"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaapLiabilitiesCurrent_096c24"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract_f3d235" xlink:to="loc_us-gaapLiabilitiesCurrent_096c24" order="18" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="loc_us-gaapStockholdersEquityAbstract_9bf1d2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapLiabilitiesCurrentAbstract_f3d235" xlink:to="loc_us-gaapStockholdersEquityAbstract_9bf1d2" order="19"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaapCommonStockValue_a72b86"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityAbstract_9bf1d2" xlink:to="loc_us-gaapCommonStockValue_a72b86" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="loc_us-gaapAdditionalPaidInCapital_fec356"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityAbstract_9bf1d2" xlink:to="loc_us-gaapAdditionalPaidInCapital_fec356" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaapRetainedEarningsAccumulatedDeficit_89c3e5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityAbstract_9bf1d2" xlink:to="loc_us-gaapRetainedEarningsAccumulatedDeficit_89c3e5" order="22"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity_8c7527"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityAbstract_9bf1d2" xlink:to="loc_us-gaapStockholdersEquity_8c7527" order="23" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaapLiabilitiesAndStockholdersEquity_ec4ed3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityAbstract_9bf1d2" xlink:to="loc_us-gaapLiabilitiesAndStockholdersEquity_ec4ed3" order="24" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:title="000003 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaapStatementOfFinancialPositionAbstract_20080a"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockNoParValue" xlink:label="loc_us-gaapCommonStockNoParValue_03905f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract_20080a" xlink:to="loc_us-gaapCommonStockNoParValue_03905f" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaapCommonStockSharesAuthorized_98eea2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract_20080a" xlink:to="loc_us-gaapCommonStockSharesAuthorized_98eea2" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaapCommonStockSharesIssued_9f63ed"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract_20080a" xlink:to="loc_us-gaapCommonStockSharesIssued_9f63ed" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaapCommonStockSharesOutstanding_e12824"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfFinancialPositionAbstract_20080a" xlink:to="loc_us-gaapCommonStockSharesOutstanding_e12824" order="4"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/UnauditedCondensedConsolidatedStatementsOfOperations" xlink:title="000004 - Statement - UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaapIncomeStatementAbstract_d4299a"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Revenues" xlink:label="loc_us-gaapRevenues_6edbf6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract_d4299a" xlink:to="loc_us-gaapRevenues_6edbf6" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaapCostOfRevenue_c1ff15"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract_d4299a" xlink:to="loc_us-gaapCostOfRevenue_c1ff15" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GrossProfit" xlink:label="loc_us-gaapGrossProfit_903b44"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract_d4299a" xlink:to="loc_us-gaapGrossProfit_903b44" order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="loc_us-gaapOperatingExpensesAbstract_6a6b9f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncomeStatementAbstract_d4299a" xlink:to="loc_us-gaapOperatingExpensesAbstract_6a6b9f" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaapResearchAndDevelopmentExpense_33131d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract_6a6b9f" xlink:to="loc_us-gaapResearchAndDevelopmentExpense_33131d" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SellingGeneralAndAdministrativeExpense" xlink:label="loc_us-gaapSellingGeneralAndAdministrativeExpense_972e48"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract_6a6b9f" xlink:to="loc_us-gaapSellingGeneralAndAdministrativeExpense_972e48" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaapAmortizationOfIntangibleAssets_f638f5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract_6a6b9f" xlink:to="loc_us-gaapAmortizationOfIntangibleAssets_f638f5" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpenses" xlink:label="loc_us-gaapOperatingExpenses_bec116"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract_6a6b9f" xlink:to="loc_us-gaapOperatingExpenses_bec116" order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaapOperatingIncomeLoss_0c792b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract_6a6b9f" xlink:to="loc_us-gaapOperatingIncomeLoss_0c792b" order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOperatingExpensesAbstract_6a6b9f" xlink:to="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaapInterestExpense_d65480"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapInterestExpense_d65480" order="11" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_GainOnExtinguishmentOfConvertibleNotes" xlink:label="loc_celzGainOnExtinguishmentOfConvertibleNotes_d172cc"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_celzGainOnExtinguishmentOfConvertibleNotes_d172cc" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ChangeInFairValueOfDerivativesLiabilities" xlink:label="loc_celzChangeInFairValueOfDerivativesLiabilities_fc7b16"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_celzChangeInFairValueOfDerivativesLiabilities_fc7b16" order="13"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaapNonoperatingIncomeExpense_620f95"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapNonoperatingIncomeExpense_620f95" order="14" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_471c47"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_471c47" order="15" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInIncomeTaxes" xlink:label="loc_us-gaapIncreaseDecreaseInIncomeTaxes_1b4746"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapIncreaseDecreaseInIncomeTaxes_1b4746" order="16"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss_d74d94"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapNetIncomeLoss_d74d94" order="17" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaapEarningsPerShareBasic_d7330c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapEarningsPerShareBasic_d7330c" order="18"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaapEarningsPerShareDiluted_b5e30b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapEarningsPerShareDiluted_b5e30b" order="19"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaapWeightedAverageNumberOfSharesOutstandingBasic_2c7ccf"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_us-gaapWeightedAverageNumberOfSharesOutstandingBasic_2c7ccf" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_WeightedAverageNumberOfSharesOutstandingDiluted" xlink:label="loc_celzWeightedAverageNumberOfSharesOutstandingDiluted_4a464a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNonoperatingIncomeExpenseAbstract_66546d" xlink:to="loc_celzWeightedAverageNumberOfSharesOutstandingDiluted_4a464a" order="21"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/UnauditedCondensedConsolidatedStatementsOfCashFlows" xlink:title="000005 - Statement - UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaapStatementOfCashFlowsAbstract_00d56b"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesAbstract_b341ba"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfCashFlowsAbstract_00d56b" xlink:to="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesAbstract_b341ba" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProfitLoss" xlink:label="loc_us-gaapProfitLoss_c88ef3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesAbstract_b341ba" xlink:to="loc_us-gaapProfitLoss_c88ef3" order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaapAdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_390478"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivitiesAbstract_b341ba" xlink:to="loc_us-gaapAdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_390478" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_NetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract" xlink:label="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_390478" xlink:to="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaapShareBasedCompensation_69d1f8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" xlink:to="loc_us-gaapShareBasedCompensation_69d1f8" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaapAmortizationOfIntangibleAssets_94287d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" xlink:to="loc_us-gaapAmortizationOfIntangibleAssets_94287d" order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfDebtDiscountPremium" xlink:label="loc_us-gaapAmortizationOfDebtDiscountPremium_09783a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" xlink:to="loc_us-gaapAmortizationOfDebtDiscountPremium_09783a" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInDerivativeLiabilities" xlink:label="loc_us-gaapIncreaseDecreaseInDerivativeLiabilities_81641d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" xlink:to="loc_us-gaapIncreaseDecreaseInDerivativeLiabilities_81641d" order="8" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_IncreaseInPrincipalAndAccruedInterestBalancesDueToPenaltyProvision" xlink:label="loc_celzIncreaseInPrincipalAndAccruedInterestBalancesDueToPenaltyProvision_264472"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" xlink:to="loc_celzIncreaseInPrincipalAndAccruedInterestBalancesDueToPenaltyProvision_264472" order="9" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaapGainsLossesOnExtinguishmentOfDebt_e83d0f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" xlink:to="loc_us-gaapGainsLossesOnExtinguishmentOfDebt_e83d0f" order="10" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzNetCashProvidedByUsedInOperatingActivitiesAbstract2Abstract_df600c" xlink:to="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaapIncreaseDecreaseInAccountsReceivable_ac4221"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapIncreaseDecreaseInAccountsReceivable_ac4221" order="12" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaapIncreaseDecreaseInInventories_5cc47e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapIncreaseDecreaseInInventories_5cc47e" order="13" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherCurrentAssets" xlink:label="loc_us-gaapIncreaseDecreaseInOtherCurrentAssets_bbd502"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapIncreaseDecreaseInOtherCurrentAssets_bbd502" order="14" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="loc_us-gaapIncreaseDecreaseInAccountsPayable_ed9a01"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapIncreaseDecreaseInAccountsPayable_ed9a01" order="15" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:label="loc_us-gaapIncreaseDecreaseInAccruedLiabilities_b03273"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapIncreaseDecreaseInAccruedLiabilities_b03273" order="16" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInPayablesToCustomers" xlink:label="loc_us-gaapIncreaseDecreaseInPayablesToCustomers_099ec3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapIncreaseDecreaseInPayablesToCustomers_099ec3" order="17"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInOperatingActivities_3350b8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapNetCashProvidedByUsedInOperatingActivities_3350b8" order="18" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="loc_us-gaapNetCashProvidedByUsedInInvestingActivitiesAbstract_8a5ffb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapIncreaseDecreaseInOperatingCapitalAbstract_b0afcd" xlink:to="loc_us-gaapNetCashProvidedByUsedInInvestingActivitiesAbstract_8a5ffb" order="19"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInInvestingActivities_e8df3e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivitiesAbstract_8a5ffb" xlink:to="loc_us-gaapNetCashProvidedByUsedInInvestingActivities_e8df3e" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivitiesAbstract_8a5ffb" xlink:to="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleMaturityAndCollectionsOfInvestments" xlink:label="loc_us-gaapProceedsFromSaleMaturityAndCollectionsOfInvestments_e27c87"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapProceedsFromSaleMaturityAndCollectionsOfInvestments_e27c87" order="22"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="loc_us-gaapProceedsFromWarrantExercises_d77638"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapProceedsFromWarrantExercises_d77638" order="23"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromNotesPayable" xlink:label="loc_us-gaapProceedsFromNotesPayable_406498"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapProceedsFromNotesPayable_406498" order="24"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromConvertibleDebt" xlink:label="loc_us-gaapProceedsFromConvertibleDebt_ae3d1f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapProceedsFromConvertibleDebt_ae3d1f" order="25"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock" xlink:label="loc_us-gaapProceedsFromIssuanceOfConvertiblePreferredStock_096d1a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapProceedsFromIssuanceOfConvertiblePreferredStock_096d1a" order="26"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromRelatedPartyDebt" xlink:label="loc_us-gaapProceedsFromRelatedPartyDebt_9d3c81"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapProceedsFromRelatedPartyDebt_9d3c81" order="27"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RepaymentsOfConvertibleDebt" xlink:label="loc_us-gaapRepaymentsOfConvertibleDebt_78f72d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapRepaymentsOfConvertibleDebt_78f72d" order="28" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInFinancingActivities_c05b9b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapNetCashProvidedByUsedInFinancingActivities_c05b9b" order="29" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_8d0d41"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect_8d0d41" order="30" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaapCashAndCashEquivalentsAtCarryingValue_d4e220"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapCashAndCashEquivalentsAtCarryingValue_d4e220" order="31" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaapCashAndCashEquivalentsAtCarryingValue_d3496f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapCashAndCashEquivalentsAtCarryingValue_d3496f" order="32" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:label="loc_us-gaapCashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_503ef3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivitiesAbstract_1e3568" xlink:to="loc_us-gaapCashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_503ef3" order="33"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ConversionOfNotesPayableAccruedInterestAndDerivativeLiabilitiesIntoCommonStock" xlink:label="loc_celzConversionOfNotesPayableAccruedInterestAndDerivativeLiabilitiesIntoCommonStock_f59b0f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_503ef3" xlink:to="loc_celzConversionOfNotesPayableAccruedInterestAndDerivativeLiabilitiesIntoCommonStock_f59b0f" order="34"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ConversionOfManagementFeesAndPatentLiabilityIntoCommonStock" xlink:label="loc_celzConversionOfManagementFeesAndPatentLiabilityIntoCommonStock_7fdf57"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_503ef3" xlink:to="loc_celzConversionOfManagementFeesAndPatentLiabilityIntoCommonStock_7fdf57" order="35"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DiscountsOnConvertibleNotesPayableDueToDerivativeLiabilities" xlink:label="loc_celzDiscountsOnConvertibleNotesPayableDueToDerivativeLiabilities_b41718"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapCashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_503ef3" xlink:to="loc_celzDiscountsOnConvertibleNotesPayableDueToDerivativeLiabilities_b41718" order="36"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/UnauditedCondensedConsolidatedStatementsOfStockholdersEquityDeficit" xlink:title="000006 - Statement - UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaapStatementOfStockholdersEquityAbstract_1d90c8"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_eed8c3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementOfStockholdersEquityAbstract_1d90c8" xlink:to="loc_us-gaapStatementTable_eed8c3" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_5a4cef"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_eed8c3" xlink:to="loc_us-gaapStatementLineItems_5a4cef" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaapStatementEquityComponentsAxis_cf9796"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_eed8c3" xlink:to="loc_us-gaapStatementEquityComponentsAxis_cf9796" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaapEquityComponentDomain_83668f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementEquityComponentsAxis_cf9796" xlink:to="loc_us-gaapEquityComponentDomain_83668f" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_SeriesBPreferredStocksMember" xlink:label="loc_celzSeriesBPreferredStocksMember_14aac3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityComponentDomain_83668f" xlink:to="loc_celzSeriesBPreferredStocksMember_14aac3" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_SeriesCPreferredStocksMember" xlink:label="loc_celzSeriesCPreferredStocksMember_96e88a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityComponentDomain_83668f" xlink:to="loc_celzSeriesCPreferredStocksMember_96e88a" order="22"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaapCommonStockMember_6b53fc"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityComponentDomain_83668f" xlink:to="loc_us-gaapCommonStockMember_6b53fc" order="23"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaapAdditionalPaidInCapitalMember_f5b843"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityComponentDomain_83668f" xlink:to="loc_us-gaapAdditionalPaidInCapitalMember_f5b843" order="24"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_SeriesAPreferredStocksMember" xlink:label="loc_celzSeriesAPreferredStocksMember_611d1c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityComponentDomain_83668f" xlink:to="loc_celzSeriesAPreferredStocksMember_611d1c" order="25"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaapRetainedEarningsMember_b204f3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityComponentDomain_83668f" xlink:to="loc_us-gaapRetainedEarningsMember_b204f3" order="26"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaapSharesIssued_3e359e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapSharesIssued_3e359e" order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity_c69e73"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapStockholdersEquity_c69e73" order="2" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ProceedsFromSalesOfPreferredStockShares" xlink:label="loc_celzProceedsFromSalesOfPreferredStockShares_62befb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzProceedsFromSalesOfPreferredStockShares_62befb" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ProceedsFromSalesOfPreferredStockAmount" xlink:label="loc_celzProceedsFromSalesOfPreferredStockAmount_81d225"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzProceedsFromSalesOfPreferredStockAmount_81d225" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssuedForRelatedPartyManagementLiabilitiesShares" xlink:label="loc_celzCommonStockIssuedForRelatedPartyManagementLiabilitiesShares_2d5143"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCommonStockIssuedForRelatedPartyManagementLiabilitiesShares_2d5143" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssuedForRelatedPartyManagementLiabilitiesAmount" xlink:label="loc_celzCommonStockIssuedForRelatedPartyManagementLiabilitiesAmount_9508a6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCommonStockIssuedForRelatedPartyManagementLiabilitiesAmount_9508a6" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_be32ab"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_be32ab" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities" xlink:label="loc_us-gaapStockIssuedDuringPeriodValueConversionOfConvertibleSecurities_40cfc7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapStockIssuedDuringPeriodValueConversionOfConvertibleSecurities_40cfc7" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeGainOnDerivative" xlink:label="loc_us-gaapDerivativeGainOnDerivative_63ad11"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapDerivativeGainOnDerivative_63ad11" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DividendsOnPreferredStock" xlink:label="loc_celzDividendsOnPreferredStock_44728a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzDividendsOnPreferredStock_44728a" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CashlessExerciseOfWarrantsShares" xlink:label="loc_celzCashlessExerciseOfWarrantsShares_81af68"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCashlessExerciseOfWarrantsShares_81af68" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CashlessExerciseOfWarrantsAmount" xlink:label="loc_celzCashlessExerciseOfWarrantsAmount_aa5e32"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCashlessExerciseOfWarrantsAmount_aa5e32" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_StockBasedCompensation" xlink:label="loc_celzStockBasedCompensation_5ef77f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzStockBasedCompensation_5ef77f" order="13" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss_f7f0e5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapNetIncomeLoss_f7f0e5" order="14" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_IssuanceOfCommonStockAndAccompanyingWarrantsNetOfIssuanceCostsShares" xlink:label="loc_celzIssuanceOfCommonStockAndAccompanyingWarrantsNetOfIssuanceCostsShares_a12dcb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzIssuanceOfCommonStockAndAccompanyingWarrantsNetOfIssuanceCostsShares_a12dcb" order="15"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_IssuanceOfCommonStockAndAccompanyingWarrantsNetOfIssuanceCostsAmount" xlink:label="loc_celzIssuanceOfCommonStockAndAccompanyingWarrantsNetOfIssuanceCostsAmount_7f0553"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzIssuanceOfCommonStockAndAccompanyingWarrantsNetOfIssuanceCostsAmount_7f0553" order="16"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssuedForRelatedPartyPatentLiabilitiesShares" xlink:label="loc_celzCommonStockIssuedForRelatedPartyPatentLiabilitiesShares_a615a7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCommonStockIssuedForRelatedPartyPatentLiabilitiesShares_a615a7" order="17"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssuedForRelatedPartyPatentLiabilitiesAmount" xlink:label="loc_celzCommonStockIssuedForRelatedPartyPatentLiabilitiesAmount_dcfed1"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCommonStockIssuedForRelatedPartyPatentLiabilitiesAmount_dcfed1" order="18"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssuedForWarrantExerciseShares" xlink:label="loc_celzCommonStockIssuedForWarrantExerciseShares_a7530f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCommonStockIssuedForWarrantExerciseShares_a7530f" order="19"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssuedForWarrantExerciseAmount" xlink:label="loc_celzCommonStockIssuedForWarrantExerciseAmount_27dc71"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_celzCommonStockIssuedForWarrantExerciseAmount_27dc71" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaapSharesIssued_01b2c7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapSharesIssued_01b2c7" order="21" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity_4d849b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_5a4cef" xlink:to="loc_us-gaapStockholdersEquity_4d849b" order="22" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPolicies" xlink:title="000007 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_e4f989"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock" xlink:label="loc_us-gaapOrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock_094d22"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_e4f989" xlink:to="loc_us-gaapOrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock_094d22" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/LicensingAgreements" xlink:title="000008 - Disclosure - LICENSING AGREEMENTS"> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicensingAgreementsAbstract" xlink:label="loc_celzLicensingAgreementsAbstract_49aed6"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicensingAgreementsDisclosureTextBlock" xlink:label="loc_celzLicensingAgreementsDisclosureTextBlock_62b429"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzLicensingAgreementsAbstract_49aed6" xlink:to="loc_celzLicensingAgreementsDisclosureTextBlock_62b429" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/RelatedPartyTransactions" xlink:title="000009 - Disclosure - RELATED PARTY TRANSACTIONS"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="loc_us-gaapRelatedPartyTransactionsAbstract_25ce83"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionsDisclosureTextBlock" xlink:label="loc_us-gaapRelatedPartyTransactionsDisclosureTextBlock_23b401"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionsAbstract_25ce83" xlink:to="loc_us-gaapRelatedPartyTransactionsDisclosureTextBlock_23b401" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/DEBT" xlink:title="000010 - Disclosure - DEBT"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaapDebtDisclosureAbstract_f4457f"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaapDebtDisclosureTextBlock_0254ea"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDebtDisclosureAbstract_f4457f" xlink:to="loc_us-gaapDebtDisclosureTextBlock_0254ea" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/DerivativeLiabilities" xlink:title="000011 - Disclosure - DERIVATIVE LIABILITIES"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_us-gaapDerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_7be03d"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:label="loc_us-gaapDerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_4f792f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_7be03d" xlink:to="loc_us-gaapDerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_4f792f" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockbasedCompensation" xlink:title="000012 - Disclosure - STOCKBASED COMPENSATION"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaapDisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_cb055d"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DisclosureOfCompensationRelatedCostsShareBasedPaymentsDisclosureTextBlock" xlink:label="loc_celzDisclosureOfCompensationRelatedCostsShareBasedPaymentsDisclosureTextBlock_1f674d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_cb055d" xlink:to="loc_celzDisclosureOfCompensationRelatedCostsShareBasedPaymentsDisclosureTextBlock_1f674d" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockholdersEquity" xlink:title="000013 - Disclosure - STOCKHOLDERS EQUITY"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaapEquityAbstract_427412"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="loc_us-gaapStockholdersEquityNoteDisclosureTextBlock_327cd8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityAbstract_427412" xlink:to="loc_us-gaapStockholdersEquityNoteDisclosureTextBlock_327cd8" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/SubsequentEvents" xlink:title="000014 - Disclosure - SUBSEQUENT EVENTS"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="loc_us-gaapSubsequentEventsAbstract_30827e"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsequentEventsTextBlock" xlink:label="loc_us-gaapSubsequentEventsTextBlock_f80046"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapSubsequentEventsAbstract_30827e" xlink:to="loc_us-gaapSubsequentEventsTextBlock_f80046" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesPolicies" xlink:title="000015 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="loc_us-gaapConsolidationPolicyTextBlock_e3c6f7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_us-gaapConsolidationPolicyTextBlock_e3c6f7" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UseOfEstimates" xlink:label="loc_us-gaapUseOfEstimates_4c7c89"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_us-gaapUseOfEstimates_4c7c89" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock" xlink:label="loc_us-gaapBusinessDescriptionAndBasisOfPresentationTextBlock_bf07eb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_us-gaapBusinessDescriptionAndBasisOfPresentationTextBlock_bf07eb" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_RisksAndUncertaintiespolicyTextBlock" xlink:label="loc_celzRisksAndUncertaintiespolicyTextBlock_2bfcc3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_celzRisksAndUncertaintiespolicyTextBlock_2bfcc3" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock" xlink:label="loc_us-gaapRevenueFromContractWithCustomerPolicyTextBlock_b11152"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_us-gaapRevenueFromContractWithCustomerPolicyTextBlock_b11152" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ConcentrationRiskPolicyTextBlock" xlink:label="loc_celzConcentrationRiskPolicyTextBlock_bfdd15"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_celzConcentrationRiskPolicyTextBlock_bfdd15" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy" xlink:label="loc_us-gaapFairValueOfFinancialInstrumentsPolicy_c6666e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_us-gaapFairValueOfFinancialInstrumentsPolicy_c6666e" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerSharePolicyTextBlock" xlink:label="loc_us-gaapEarningsPerSharePolicyTextBlock_28475e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_us-gaapEarningsPerSharePolicyTextBlock_28475e" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaapNewAccountingPronouncementsPolicyPolicyTextBlock_9458fa"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d9aa2" xlink:to="loc_us-gaapNewAccountingPronouncementsPolicyPolicyTextBlock_9458fa" order="9"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesTables" xlink:title="000016 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_4e071d"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="loc_us-gaapScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_2e5900"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_4e071d" xlink:to="loc_us-gaapScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_2e5900" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/LicensingAgreementsTables" xlink:title="000017 - Disclosure - LICENSING AGREEMENTS (Tables)"> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicensingAgreementsAbstract" xlink:label="loc_celzLicensingAgreementsAbstract_a4ad9a"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ScheduleOfLicensingAgreementsTableTextBlock" xlink:label="loc_celzScheduleOfLicensingAgreementsTableTextBlock_bda5e1"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzLicensingAgreementsAbstract_a4ad9a" xlink:to="loc_celzScheduleOfLicensingAgreementsTableTextBlock_bda5e1" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockbasedCompensationTables" xlink:title="000018 - Disclosure - STOCKBASED COMPENSATION (Tables)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaapDisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ec62d4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ScheduleValueOfOptionsTableTextBlock" xlink:label="loc_celzScheduleValueOfOptionsTableTextBlock_751ec7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ec62d4" xlink:to="loc_celzScheduleValueOfOptionsTableTextBlock_751ec7" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:label="loc_us-gaapScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_86a44a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ec62d4" xlink:to="loc_us-gaapScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_86a44a" order="2"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockholdersEquityTables" xlink:title="000019 - Disclosure - STOCKHOLDERS EQUITY (Tables)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaapEquityAbstract_a66c1c"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ScheduleOfIssuancesAndExercisesTableTextBlock" xlink:label="loc_celzScheduleOfIssuancesAndExercisesTableTextBlock_cfe927"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityAbstract_a66c1c" xlink:to="loc_celzScheduleOfIssuancesAndExercisesTableTextBlock_cfe927" order="1"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesDetails" xlink:title="000020 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_WeightedAverageCommonSharesOutstandingUsedInCalculatingBasicEarningsPerShare" xlink:label="loc_celzWeightedAverageCommonSharesOutstandingUsedInCalculatingBasicEarningsPerShare_fd3a4c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_celzWeightedAverageCommonSharesOutstandingUsedInCalculatingBasicEarningsPerShare_fd3a4c" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_EffectOfSeriesBAndCPreferredStockShare" xlink:label="loc_celzEffectOfSeriesBAndCPreferredStockShare_002aaa"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_celzEffectOfSeriesBAndCPreferredStockShare_002aaa" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncrementalCommonSharesAttributableToCallOptionsAndWarrants" xlink:label="loc_us-gaapIncrementalCommonSharesAttributableToCallOptionsAndWarrants_c7f67a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_us-gaapIncrementalCommonSharesAttributableToCallOptionsAndWarrants_c7f67a" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities" xlink:label="loc_us-gaapIncrementalCommonSharesAttributableToConversionOfDebtSecurities_66bd35"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_us-gaapIncrementalCommonSharesAttributableToConversionOfDebtSecurities_66bd35" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_IncrementalCommonSharesAttributableToDilutiveEffectOfConvertibleRelatedPartyManagementFeeAndPatentLiabilities" xlink:label="loc_celzIncrementalCommonSharesAttributableToDilutiveEffectOfConvertibleRelatedPartyManagementFeeAndPatentLiabilities_4b97a3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_celzIncrementalCommonSharesAttributableToDilutiveEffectOfConvertibleRelatedPartyManagementFeeAndPatentLiabilities_4b97a3" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaapWeightedAverageNumberOfDilutedSharesOutstanding_47db28"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_us-gaapWeightedAverageNumberOfDilutedSharesOutstanding_47db28" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaapNetIncomeLossAvailableToCommonStockholdersBasic_cba1e2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_us-gaapNetIncomeLossAvailableToCommonStockholdersBasic_cba1e2" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestOnConvertibleDebtNetOfTax" xlink:label="loc_us-gaapInterestOnConvertibleDebtNetOfTax_afc414"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_us-gaapInterestOnConvertibleDebtNetOfTax_afc414" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:label="loc_us-gaapNetIncomeLossAvailableToCommonStockholdersDiluted_7a2f1e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapOrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_8632d7" xlink:to="loc_us-gaapNetIncomeLossAvailableToCommonStockholdersDiluted_7a2f1e" order="9"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/OrganizationAndSummaryOfSignificantAccountingPoliciesDetailsNarrative" xlink:title="000021 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaapAccountingPoliciesAbstract_3ac033"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_facb1e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAccountingPoliciesAbstract_3ac033" xlink:to="loc_us-gaapStatementTable_facb1e" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_a7036d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_facb1e" xlink:to="loc_us-gaapStatementLineItems_a7036d" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis" xlink:label="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_a819f3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_facb1e" xlink:to="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_a819f3" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaapAntidilutiveSecuritiesNameDomain_9d0f99"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_a819f3" xlink:to="loc_us-gaapAntidilutiveSecuritiesNameDomain_9d0f99" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_WarrantsMember" xlink:label="loc_celzWarrantsMember_a70ca7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAntidilutiveSecuritiesNameDomain_9d0f99" xlink:to="loc_celzWarrantsMember_a70ca7" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_OptionsMember" xlink:label="loc_celzOptionsMember_76eada"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAntidilutiveSecuritiesNameDomain_9d0f99" xlink:to="loc_celzOptionsMember_76eada" order="22"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TimeDepositsAtOrAboveFDICInsuranceLimit" xlink:label="loc_us-gaapTimeDepositsAtOrAboveFDICInsuranceLimit_d75bab"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_a7036d" xlink:to="loc_us-gaapTimeDepositsAtOrAboveFDICInsuranceLimit_d75bab" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_bd15e8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_a7036d" xlink:to="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_bd15e8" order="2"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/LicensingAgreementsDetails" xlink:title="000022 - Disclosure - LICENSING AGREEMENTS (Details)"> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicensingAgreementsAbstract" xlink:label="loc_celzLicensingAgreementsAbstract_a83710"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AssetAbstract" xlink:label="loc_celzAssetAbstract_c68e30"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzLicensingAgreementsAbstract_a83710" xlink:to="loc_celzAssetAbstract_c68e30" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicensingAgreementsBeginningBalance" xlink:label="loc_celzLicensingAgreementsBeginningBalance_d0f5eb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAssetAbstract_c68e30" xlink:to="loc_celzLicensingAgreementsBeginningBalance_d0f5eb" order="2" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DepreciationAndAmortization" xlink:label="loc_us-gaapDepreciationAndAmortization_47fb75"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAssetAbstract_c68e30" xlink:to="loc_us-gaapDepreciationAndAmortization_47fb75" order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicensingAgreementsendingbalance" xlink:label="loc_celzLicensingAgreementsendingbalance_8a794e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAssetAbstract_c68e30" xlink:to="loc_celzLicensingAgreementsendingbalance_8a794e" order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AccumulatedAmortizationAbstract" xlink:label="loc_celzAccumulatedAmortizationAbstract_5e4733"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAssetAbstract_c68e30" xlink:to="loc_celzAccumulatedAmortizationAbstract_5e4733" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AccumulatedAmortizationBeginningBalance" xlink:label="loc_celzAccumulatedAmortizationBeginningBalance_6fd87e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAccumulatedAmortizationAbstract_5e4733" xlink:to="loc_celzAccumulatedAmortizationBeginningBalance_6fd87e" order="6" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AccumulatedAmortizationAdditionOfNewAssets" xlink:label="loc_celzAccumulatedAmortizationAdditionOfNewAssets_cda82a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAccumulatedAmortizationAbstract_5e4733" xlink:to="loc_celzAccumulatedAmortizationAdditionOfNewAssets_cda82a" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AccumulatedAmortization" xlink:label="loc_celzAccumulatedAmortization_769f69"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAccumulatedAmortizationAbstract_5e4733" xlink:to="loc_celzAccumulatedAmortization_769f69" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AccumulatedAmortizationEndingBalance" xlink:label="loc_celzAccumulatedAmortizationEndingBalance_cf8a7b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzAccumulatedAmortizationAbstract_5e4733" xlink:to="loc_celzAccumulatedAmortizationEndingBalance_cf8a7b" order="9" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/LicensingAgreementsDetailsNarrative" xlink:title="000023 - Disclosure - LICENSING AGREEMENTS (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicensingAgreementsAbstract" xlink:label="loc_celzLicensingAgreementsAbstract_6dad1c"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_aa05c1"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzLicensingAgreementsAbstract_6dad1c" xlink:to="loc_us-gaapStatementTable_aa05c1" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_cc16bd"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aa05c1" xlink:to="loc_us-gaapStatementLineItems_cc16bd" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaapPlanNameAxis_9b88c8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aa05c1" xlink:to="loc_us-gaapPlanNameAxis_9b88c8" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaapPlanNameDomain_c88fa0"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameAxis_9b88c8" xlink:to="loc_us-gaapPlanNameDomain_c88fa0" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ConsolidatedEntitiesAxis" xlink:label="loc_srtConsolidatedEntitiesAxis_2b1872"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aa05c1" xlink:to="loc_srtConsolidatedEntitiesAxis_2b1872" order="40"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ConsolidatedEntitiesDomain" xlink:label="loc_srtConsolidatedEntitiesDomain_8318e4"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtConsolidatedEntitiesAxis_2b1872" xlink:to="loc_srtConsolidatedEntitiesDomain_8318e4" order="40"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaapFiniteLivedIntangibleAssetsByMajorClassAxis_4f3f6f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aa05c1" xlink:to="loc_us-gaapFiniteLivedIntangibleAssetsByMajorClassAxis_4f3f6f" order="60"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaapFiniteLivedIntangibleAssetsMajorClassNameDomain_df5c3f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapFiniteLivedIntangibleAssetsByMajorClassAxis_4f3f6f" xlink:to="loc_us-gaapFiniteLivedIntangibleAssetsMajorClassNameDomain_df5c3f" order="60"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialInstrumentAxis" xlink:label="loc_us-gaapFinancialInstrumentAxis_f58aec"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aa05c1" xlink:to="loc_us-gaapFinancialInstrumentAxis_f58aec" order="80"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:label="loc_us-gaapTransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_02bbe0"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapFinancialInstrumentAxis_f58aec" xlink:to="loc_us-gaapTransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_02bbe0" order="80"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_StatementScenarioAxis" xlink:label="loc_srtStatementScenarioAxis_e803d6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aa05c1" xlink:to="loc_srtStatementScenarioAxis_e803d6" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ScenarioUnspecifiedDomain" xlink:label="loc_srtScenarioUnspecifiedDomain_ea77a9"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtStatementScenarioAxis_e803d6" xlink:to="loc_srtScenarioUnspecifiedDomain_ea77a9" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PatentLicenseAgreementMember" xlink:label="loc_celzPatentLicenseAgreementMember_b9fefd"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameDomain_c88fa0" xlink:to="loc_celzPatentLicenseAgreementMember_b9fefd" order="101"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_StemspineLLCMember" xlink:label="loc_celzStemspineLLCMember_db9a57"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtConsolidatedEntitiesDomain_8318e4" xlink:to="loc_celzStemspineLLCMember_db9a57" order="102"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PatentsMember" xlink:label="loc_us-gaapPatentsMember_f0ff5c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapFiniteLivedIntangibleAssetsMajorClassNameDomain_df5c3f" xlink:to="loc_us-gaapPatentsMember_f0ff5c" order="103"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_MultipotentAmnioticFetalStemCellsLicenseAgreementMember" xlink:label="loc_celzMultipotentAmnioticFetalStemCellsLicenseAgreementMember_3aa3b2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameDomain_c88fa0" xlink:to="loc_celzMultipotentAmnioticFetalStemCellsLicenseAgreementMember_3aa3b2" order="104"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CreativeMedicalHealthIncMember" xlink:label="loc_celzCreativeMedicalHealthIncMember_bdaa6c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtConsolidatedEntitiesDomain_8318e4" xlink:to="loc_celzCreativeMedicalHealthIncMember_bdaa6c" order="105"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OptionMember" xlink:label="loc_us-gaapOptionMember_cc0b5e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapTransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_02bbe0" xlink:to="loc_us-gaapOptionMember_cc0b5e" order="106"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ScenarioOneMember" xlink:label="loc_celzScenarioOneMember_43efa0"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtScenarioUnspecifiedDomain_ea77a9" xlink:to="loc_celzScenarioOneMember_43efa0" order="107"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ScenarioTwoMember" xlink:label="loc_celzScenarioTwoMember_0b1e7f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtScenarioUnspecifiedDomain_ea77a9" xlink:to="loc_celzScenarioTwoMember_0b1e7f" order="108"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CompanyPaid" xlink:label="loc_celzCompanyPaid_f350ef"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzCompanyPaid_f350ef" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssueShare" xlink:label="loc_celzCommonStockIssueShare_999e41"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzCommonStockIssueShare_999e41" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ObligationOfTheInitialPayment" xlink:label="loc_celzObligationOfTheInitialPayment_35b993"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzObligationOfTheInitialPayment_35b993" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicenseFees" xlink:label="loc_celzLicenseFees_1afbfa"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzLicenseFees_1afbfa" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CashPaymentInIntialPayment" xlink:label="loc_celzCashPaymentInIntialPayment_d08035"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzCashPaymentInIntialPayment_d08035" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicenseAgreementDescription" xlink:label="loc_celzLicenseAgreementDescription_cfac00"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzLicenseAgreementDescription_cfac00" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_LicenseAgreementDescriptionFinal" xlink:label="loc_celzLicenseAgreementDescriptionFinal_33815b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzLicenseAgreementDescriptionFinal_33815b" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_NoOfShareExchange" xlink:label="loc_celzNoOfShareExchange_fe463b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzNoOfShareExchange_fe463b" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_RestrictedCommonStock" xlink:label="loc_celzRestrictedCommonStock_176a4a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzRestrictedCommonStock_176a4a" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AmortizationExpenses" xlink:label="loc_celzAmortizationExpenses_7b87bc"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzAmortizationExpenses_7b87bc" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherIntangibleAssetsNet" xlink:label="loc_us-gaapOtherIntangibleAssetsNet_db449f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_us-gaapOtherIntangibleAssetsNet_db449f" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ExpirationPeriodOfFiniteLivedIntangibleAssets" xlink:label="loc_celzExpirationPeriodOfFiniteLivedIntangibleAssets_728e7c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzExpirationPeriodOfFiniteLivedIntangibleAssets_728e7c" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ExpectedAmountOfAmortization" xlink:label="loc_celzExpectedAmountOfAmortization_bb710b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzExpectedAmountOfAmortization_bb710b" order="13"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_InitialPaymentsToAcquireIntangibleAssets" xlink:label="loc_celzInitialPaymentsToAcquireIntangibleAssets_856a5c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzInitialPaymentsToAcquireIntangibleAssets_856a5c" order="14"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PercentageOfDiscountOnTheBasisOfRecentTradingPrice" xlink:label="loc_celzPercentageOfDiscountOnTheBasisOfRecentTradingPrice_eef241"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzPercentageOfDiscountOnTheBasisOfRecentTradingPrice_eef241" order="15"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_SharePriceForTwoOrMoreConsecutiveTradingDays" xlink:label="loc_celzSharePriceForTwoOrMoreConsecutiveTradingDays_b402eb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzSharePriceForTwoOrMoreConsecutiveTradingDays_b402eb" order="16"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaapAmortizationOfIntangibleAssets_318e0b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_us-gaapAmortizationOfIntangibleAssets_318e0b" order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_NumberOfShareIssuanceOfCommonStockToJadiCell" xlink:label="loc_celzNumberOfShareIssuanceOfCommonStockToJadiCell_14103c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzNumberOfShareIssuanceOfCommonStockToJadiCell_14103c" order="18"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PaymentsUponSigningAgreementWithUniversityForInitiationOfIrbClinicalTrial" xlink:label="loc_celzPaymentsUponSigningAgreementWithUniversityForInitiationOfIrbClinicalTrial_e4d085"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzPaymentsUponSigningAgreementWithUniversityForInitiationOfIrbClinicalTrial_e4d085" order="19"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PaymentsUponCompletionOfIrbClinicalTrial" xlink:label="loc_celzPaymentsUponCompletionOfIrbClinicalTrial_1300f1"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzPaymentsUponCompletionOfIrbClinicalTrial_1300f1" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PaymentsInTheEventOfCommercializationOfTechnology" xlink:label="loc_celzPaymentsInTheEventOfCommercializationOfTechnology_ee2170"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzPaymentsInTheEventOfCommercializationOfTechnology_ee2170" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PaymentsUponFilingIndWithFda" xlink:label="loc_celzPaymentsUponFilingIndWithFda_35dbeb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzPaymentsUponFilingIndWithFda_35dbeb" order="22"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PaymentsUponDosingOfFirstPatientInPhase12ClinicalTrial" xlink:label="loc_celzPaymentsUponDosingOfFirstPatientInPhase12ClinicalTrial_6f5f7a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzPaymentsUponDosingOfFirstPatientInPhase12ClinicalTrial_6f5f7a" order="23"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PaymentsUponDosingOfFirstPatientInPhase3ClinicalTrial" xlink:label="loc_celzPaymentsUponDosingOfFirstPatientInPhase3ClinicalTrial_379107"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzPaymentsUponDosingOfFirstPatientInPhase3ClinicalTrial_379107" order="24"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_RoyaltyPaymentPercentage" xlink:label="loc_celzRoyaltyPaymentPercentage_9d223d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzRoyaltyPaymentPercentage_9d223d" order="25"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_NonroyaltySubleaseIncomePercentage" xlink:label="loc_celzNonroyaltySubleaseIncomePercentage_4ff9b7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_cc16bd" xlink:to="loc_celzNonroyaltySubleaseIncomePercentage_4ff9b7" order="26"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/RelatedPartyTransactionsDetailsNarrative" xlink:title="000024 - Disclosure - RELATED PARTY TRANSACTIONS (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="loc_us-gaapRelatedPartyTransactionsAbstract_ff071e"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_ee2889"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionsAbstract_ff071e" xlink:to="loc_us-gaapStatementTable_ee2889" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_854f7a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_ee2889" xlink:to="loc_us-gaapStatementLineItems_854f7a" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis_29d597"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_ee2889" xlink:to="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis_29d597" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaapRelatedPartyDomain_fa1e9b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis_29d597" xlink:to="loc_us-gaapRelatedPartyDomain_fa1e9b" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ManagementReimbursementAgreementCMHMember" xlink:label="loc_celzManagementReimbursementAgreementCMHMember_b294d4"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain_fa1e9b" xlink:to="loc_celzManagementReimbursementAgreementCMHMember_b294d4" order="21"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_StemSpinePatentPurchaseMember" xlink:label="loc_celzStemSpinePatentPurchaseMember_786f19"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain_fa1e9b" xlink:to="loc_celzStemSpinePatentPurchaseMember_786f19" order="22"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DebtSettlementAgreementTimothyWarbingtonMember" xlink:label="loc_celzDebtSettlementAgreementTimothyWarbingtonMember_0aeff7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain_fa1e9b" xlink:to="loc_celzDebtSettlementAgreementTimothyWarbingtonMember_0aeff7" order="23"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_JadiCellLicenseAgreementMember" xlink:label="loc_celzJadiCellLicenseAgreementMember_21c259"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain_fa1e9b" xlink:to="loc_celzJadiCellLicenseAgreementMember_21c259" order="24"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ProceedsFromDirector" xlink:label="loc_celzProceedsFromDirector_efef37"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzProceedsFromDirector_efef37" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ProceedsFromChairman" xlink:label="loc_celzProceedsFromChairman_d8f1e4"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzProceedsFromChairman_d8f1e4" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaapDebtInstrumentInterestRateEffectivePercentage_abbb34"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_us-gaapDebtInstrumentInterestRateEffectivePercentage_abbb34" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ReimbursementOfManagementFees" xlink:label="loc_celzReimbursementOfManagementFees_1828f6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzReimbursementOfManagementFees_1828f6" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CompanyPaid" xlink:label="loc_celzCompanyPaid_61114f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzCompanyPaid_61114f" order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ObligationOfTheInitialPayment" xlink:label="loc_celzObligationOfTheInitialPayment_05b356"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzObligationOfTheInitialPayment_05b356" order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssued" xlink:label="loc_celzCommonStockIssued_3706c1"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzCommonStockIssued_3706c1" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CompanyOwedCmh" xlink:label="loc_celzCompanyOwedCmh_bb820e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzCompanyOwedCmh_bb820e" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermPurchaseCommitmentAmount" xlink:label="loc_us-gaapLongTermPurchaseCommitmentAmount_cffead"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_us-gaapLongTermPurchaseCommitmentAmount_cffead" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CashPaymentInIntialPayment" xlink:label="loc_celzCashPaymentInIntialPayment_dc8d59"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzCashPaymentInIntialPayment_dc8d59" order="10" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_RemainingPortionOfObligationPaidInCash" xlink:label="loc_celzRemainingPortionOfObligationPaidInCash_81e195"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzRemainingPortionOfObligationPaidInCash_81e195" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_SeriesAPreferredStockSharesIssued" xlink:label="loc_celzSeriesAPreferredStockSharesIssued_9ed0bd"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzSeriesAPreferredStockSharesIssued_9ed0bd" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CancellationOfDebt" xlink:label="loc_celzCancellationOfDebt_13c7bd"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzCancellationOfDebt_13c7bd" order="13"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_SeriesAPreferredStockDescriptionOfSurrenderAndExchange" xlink:label="loc_celzSeriesAPreferredStockDescriptionOfSurrenderAndExchange_b7cc20"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzSeriesAPreferredStockDescriptionOfSurrenderAndExchange_b7cc20" order="14"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_Licensefee" xlink:label="loc_celzLicensefee_d393e2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzLicensefee_d393e2" order="15"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AgreementDescription" xlink:label="loc_celzAgreementDescription_fa5591"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_celzAgreementDescription_fa5591" order="16"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaapCommonStockSharesIssued_3df597"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_854f7a" xlink:to="loc_us-gaapCommonStockSharesIssued_3df597" order="17" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/DebtDetailsNarrative" xlink:title="000025 - Disclosure - DEBT (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaapDebtDisclosureAbstract_1188f5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_00c748"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDebtDisclosureAbstract_1188f5" xlink:to="loc_us-gaapStatementTable_00c748" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_6f845a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_00c748" xlink:to="loc_us-gaapStatementLineItems_6f845a" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis_dc0bef"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_00c748" xlink:to="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis_dc0bef" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaapRelatedPartyDomain_be3700"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionsByRelatedPartyAxis_dc0bef" xlink:to="loc_us-gaapRelatedPartyDomain_be3700" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShortTermDebtTypeAxis" xlink:label="loc_us-gaapShortTermDebtTypeAxis_d8dae9"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_00c748" xlink:to="loc_us-gaapShortTermDebtTypeAxis_d8dae9" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShortTermDebtTypeDomain" xlink:label="loc_us-gaapShortTermDebtTypeDomain_122715"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShortTermDebtTypeAxis_d8dae9" xlink:to="loc_us-gaapShortTermDebtTypeDomain_122715" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis" xlink:label="loc_srtRangeAxis_3254c2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_00c748" xlink:to="loc_srtRangeAxis_3254c2" order="50"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember" xlink:label="loc_srtRangeMember_7b9af9"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtRangeAxis_3254c2" xlink:to="loc_srtRangeMember_7b9af9" order="50"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AccreditedInvestorsMember" xlink:label="loc_celzAccreditedInvestorsMember_101f0e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain_be3700" xlink:to="loc_celzAccreditedInvestorsMember_101f0e" order="51"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConvertibleDebtMember" xlink:label="loc_us-gaapConvertibleDebtMember_71380e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapShortTermDebtTypeDomain_122715" xlink:to="loc_us-gaapConvertibleDebtMember_71380e" order="52"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember" xlink:label="loc_srtMinimumMember_9f924a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtRangeMember_7b9af9" xlink:to="loc_srtMinimumMember_9f924a" order="53"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember" xlink:label="loc_srtMaximumMember_259eaa"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtRangeMember_7b9af9" xlink:to="loc_srtMaximumMember_259eaa" order="54"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_BoardMember" xlink:label="loc_celzBoardMember_294cb6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain_be3700" xlink:to="loc_celzBoardMember_294cb6" order="55"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ChiefExecutiveOfficerMember" xlink:label="loc_srtChiefExecutiveOfficerMember_5c0ce5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyDomain_be3700" xlink:to="loc_srtChiefExecutiveOfficerMember_5c0ce5" order="56"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DebtConversionSharesIssued" xlink:label="loc_celzDebtConversionSharesIssued_1720d5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_celzDebtConversionSharesIssued_1720d5" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtConversionOriginalDebtAmount1" xlink:label="loc_us-gaapDebtConversionOriginalDebtAmount1_8ae91a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapDebtConversionOriginalDebtAmount1_8ae91a" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseOther" xlink:label="loc_us-gaapInterestExpenseOther_39ab32"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapInterestExpenseOther_39ab32" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DebtConversionConverrtedInstrumentSharesIssued" xlink:label="loc_celzDebtConversionConverrtedInstrumentSharesIssued_3656a1"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_celzDebtConversionConverrtedInstrumentSharesIssued_3656a1" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonStockIssuedForCashlessWarrantExerciseShares" xlink:label="loc_celzCommonStockIssuedForCashlessWarrantExerciseShares_fbecc6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_celzCommonStockIssuedForCashlessWarrantExerciseShares_fbecc6" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentUnamortizedDiscount" xlink:label="loc_us-gaapDebtInstrumentUnamortizedDiscount_cd77c0"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapDebtInstrumentUnamortizedDiscount_cd77c0" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfDebtDiscountPremium" xlink:label="loc_us-gaapAmortizationOfDebtDiscountPremium_a6ab98"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapAmortizationOfDebtDiscountPremium_a6ab98" order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromConvertibleDebt" xlink:label="loc_us-gaapProceedsFromConvertibleDebt_4a27f0"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapProceedsFromConvertibleDebt_4a27f0" order="8" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromCollectionOfAdvanceToAffiliate" xlink:label="loc_us-gaapProceedsFromCollectionOfAdvanceToAffiliate_ea5016"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapProceedsFromCollectionOfAdvanceToAffiliate_ea5016" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConvertibleNotesPayable" xlink:label="loc_us-gaapConvertibleNotesPayable_f89b68"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapConvertibleNotesPayable_f89b68" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_InterestRate" xlink:label="loc_celzInterestRate_2c0dda"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_celzInterestRate_2c0dda" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentConvertibleThresholdTradingDays" xlink:label="loc_us-gaapDebtInstrumentConvertibleThresholdTradingDays_a5f558"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapDebtInstrumentConvertibleThresholdTradingDays_a5f558" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtConversionConvertedInstrumentRate" xlink:label="loc_us-gaapDebtConversionConvertedInstrumentRate_e5e1f2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_6f845a" xlink:to="loc_us-gaapDebtConversionConvertedInstrumentRate_e5e1f2" order="13"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/DerivativeLiabilitiesDetailsNarrative" xlink:title="000026 - Disclosure - DERIVATIVE LIABILITIES (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_us-gaapDerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_83a40c"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_061f60"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapDerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_83a40c" xlink:to="loc_us-gaapStatementTable_061f60" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_ad61de"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_061f60" xlink:to="loc_us-gaapStatementLineItems_ad61de" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis" xlink:label="loc_srtRangeAxis_bc99a4"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_061f60" xlink:to="loc_srtRangeAxis_bc99a4" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember" xlink:label="loc_srtRangeMember_497d23"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtRangeAxis_bc99a4" xlink:to="loc_srtRangeMember_497d23" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaapBalanceSheetLocationAxis_ab8540"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_061f60" xlink:to="loc_us-gaapBalanceSheetLocationAxis_ab8540" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaapBalanceSheetLocationDomain_66325d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapBalanceSheetLocationAxis_ab8540" xlink:to="loc_us-gaapBalanceSheetLocationDomain_66325d" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputTypeAxis" xlink:label="loc_us-gaapMeasurementInputTypeAxis_ab694a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_061f60" xlink:to="loc_us-gaapMeasurementInputTypeAxis_ab694a" order="50"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputTypeDomain" xlink:label="loc_us-gaapMeasurementInputTypeDomain_7dff7b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapMeasurementInputTypeAxis_ab694a" xlink:to="loc_us-gaapMeasurementInputTypeDomain_7dff7b" order="50"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FreshStartAdjustmentsTypeOfFreshStartAdjustmentAxis" xlink:label="loc_us-gaapFreshStartAdjustmentsTypeOfFreshStartAdjustmentAxis_b06438"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_061f60" xlink:to="loc_us-gaapFreshStartAdjustmentsTypeOfFreshStartAdjustmentAxis_b06438" order="70"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TypeOfFreshStartAdjustmentDomain" xlink:label="loc_us-gaapTypeOfFreshStartAdjustmentDomain_7e6943"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapFreshStartAdjustmentsTypeOfFreshStartAdjustmentAxis_b06438" xlink:to="loc_us-gaapTypeOfFreshStartAdjustmentDomain_7e6943" order="70"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsegmentsAxis" xlink:label="loc_us-gaapSubsegmentsAxis_30f763"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_061f60" xlink:to="loc_us-gaapSubsegmentsAxis_30f763" order="90"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsegmentsDomain" xlink:label="loc_us-gaapSubsegmentsDomain_7975f8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapSubsegmentsAxis_30f763" xlink:to="loc_us-gaapSubsegmentsDomain_7975f8" order="90"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember" xlink:label="loc_srtMinimumMember_d832ad"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtRangeMember_497d23" xlink:to="loc_srtMinimumMember_d832ad" order="91" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_EmployeeStocksOptionMember" xlink:label="loc_celzEmployeeStocksOptionMember_1bfd55"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapBalanceSheetLocationDomain_66325d" xlink:to="loc_celzEmployeeStocksOptionMember_1bfd55" order="92"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember" xlink:label="loc_srtMaximumMember_2154e5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srtRangeMember_497d23" xlink:to="loc_srtMaximumMember_2154e5" order="93" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputPriceVolatilityMember" xlink:label="loc_us-gaapMeasurementInputPriceVolatilityMember_216d93"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapMeasurementInputTypeDomain_7dff7b" xlink:to="loc_us-gaapMeasurementInputPriceVolatilityMember_216d93" order="94"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputRiskFreeInterestRateMember" xlink:label="loc_us-gaapMeasurementInputRiskFreeInterestRateMember_c4ec22"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapMeasurementInputTypeDomain_7dff7b" xlink:to="loc_us-gaapMeasurementInputRiskFreeInterestRateMember_c4ec22" order="95"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_RevaluationMember" xlink:label="loc_celzRevaluationMember_0e7149"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapTypeOfFreshStartAdjustmentDomain_7e6943" xlink:to="loc_celzRevaluationMember_0e7149" order="96"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_MinimumssMember" xlink:label="loc_celzMinimumssMember_77eb40"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapSubsegmentsDomain_7975f8" xlink:to="loc_celzMinimumssMember_77eb40" order="97"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputExercisePriceMember" xlink:label="loc_us-gaapMeasurementInputExercisePriceMember_c0452d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapMeasurementInputTypeDomain_7dff7b" xlink:to="loc_us-gaapMeasurementInputExercisePriceMember_c0452d" order="98"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_MeasurementInputExercisePricesMember" xlink:label="loc_celzMeasurementInputExercisePricesMember_de086a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapMeasurementInputTypeDomain_7dff7b" xlink:to="loc_celzMeasurementInputExercisePricesMember_de086a" order="99" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_InitialDerivativeLiabilities" xlink:label="loc_celzInitialDerivativeLiabilities_4bff07"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_celzInitialDerivativeLiabilities_4bff07" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DerivativeLiabilitiesFairValue" xlink:label="loc_celzDerivativeLiabilitiesFairValue_180d97"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_celzDerivativeLiabilitiesFairValue_180d97" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_GainLossRelatedToChangeInFairMarketValueOfDerivativeLiabilities" xlink:label="loc_celzGainLossRelatedToChangeInFairMarketValueOfDerivativeLiabilities_e688ff"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_celzGainLossRelatedToChangeInFairMarketValueOfDerivativeLiabilities_e688ff" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConvertibleDebtCurrent" xlink:label="loc_us-gaapConvertibleDebtCurrent_295bc6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_us-gaapConvertibleDebtCurrent_295bc6" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_SharePriceOnReveluation" xlink:label="loc_celzSharePriceOnReveluation_c901a5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_celzSharePriceOnReveluation_c901a5" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_5f0daf"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_5f0daf" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeLiabilitiesNoncurrent" xlink:label="loc_us-gaapDerivativeLiabilitiesNoncurrent_cdb475"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_us-gaapDerivativeLiabilitiesNoncurrent_cdb475" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharePrice" xlink:label="loc_us-gaapSharePrice_3ccc2f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_us-gaapSharePrice_3ccc2f" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DerivativeLiabilityMeasurementInputPercentage" xlink:label="loc_celzDerivativeLiabilityMeasurementInputPercentage_c6534c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_celzDerivativeLiabilityMeasurementInputPercentage_c6534c" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_RiskFreeInterestRate" xlink:label="loc_celzRiskFreeInterestRate_19d952"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_celzRiskFreeInterestRate_19d952" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DerivativeLiabilityMeasurementInputRatios" xlink:label="loc_celzDerivativeLiabilityMeasurementInputRatios_ea2b4f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_ad61de" xlink:to="loc_celzDerivativeLiabilityMeasurementInputRatios_ea2b4f" order="11"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockbasedCompensationDetails" xlink:title="000027 - Disclosure - STOCKBASED COMPENSATION (Details)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaapStockholdersEquityNoteAbstract_5a2f31"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_AnnualDividendYield" xlink:label="loc_celzAnnualDividendYield_4b0425"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityNoteAbstract_5a2f31" xlink:to="loc_celzAnnualDividendYield_4b0425" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_890de5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityNoteAbstract_5a2f31" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_890de5" order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_259f4a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityNoteAbstract_5a2f31" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_259f4a" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_0233ea"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityNoteAbstract_5a2f31" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_0233ea" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharePrice" xlink:label="loc_us-gaapSharePrice_7577c9"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityNoteAbstract_5a2f31" xlink:to="loc_us-gaapSharePrice_7577c9" order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockbasedCompensationDetails1" xlink:title="000028 - Disclosure - STOCKBASED COMPENSATION (Details 1)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaapStockholdersEquityNoteAbstract_654b61"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_aefce3"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityNoteAbstract_654b61" xlink:to="loc_us-gaapStatementTable_aefce3" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_991df7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aefce3" xlink:to="loc_us-gaapStatementLineItems_991df7" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialInstrumentAxis" xlink:label="loc_us-gaapFinancialInstrumentAxis_c2a645"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_aefce3" xlink:to="loc_us-gaapFinancialInstrumentAxis_c2a645" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:label="loc_us-gaapTransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_fb32f6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapFinancialInstrumentAxis_c2a645" xlink:to="loc_us-gaapTransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_fb32f6" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OptionMember" xlink:label="loc_us-gaapOptionMember_7e73ba"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapTransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_fb32f6" xlink:to="loc_us-gaapOptionMember_7e73ba" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_9b080d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_9b080d" order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_5afd48"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_5afd48" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised_827f95"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised_827f95" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_6cf46d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_6cf46d" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_5b1633"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_5b1633" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_df5fd5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_df5fd5" order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_1dce20"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_1dce20" order="7" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_9ab043"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_9ab043" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_45384b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_45384b" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue_1b1b6f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue_1b1b6f" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_93dab6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_93dab6" order="11" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_WeightedAverageLifeRemainingOutstandingBeginning" xlink:label="loc_celzWeightedAverageLifeRemainingOutstandingBeginning_41e535"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_celzWeightedAverageLifeRemainingOutstandingBeginning_41e535" order="12"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsOutstandingWeightedAverageRemainingContractualTerms" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsOutstandingWeightedAverageRemainingContractualTerms_f7f302"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsOutstandingWeightedAverageRemainingContractualTerms_f7f302" order="13"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1" xlink:label="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_c5225c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_991df7" xlink:to="loc_us-gaapSharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_c5225c" order="14"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockbasedCompensationDetailsNarrative" xlink:title="000029 - Disclosure - STOCKBASED COMPENSATION (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaapEquityAbstract_312eb2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_c68b5f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapEquityAbstract_312eb2" xlink:to="loc_us-gaapStatementTable_c68b5f" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_611d08"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_c68b5f" xlink:to="loc_us-gaapStatementLineItems_611d08" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="loc_us-gaapRelatedPartyTransactionAxis_e0bf81"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_c68b5f" xlink:to="loc_us-gaapRelatedPartyTransactionAxis_e0bf81" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaapRelatedPartyTransactionDomain_062050"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionAxis_e0bf81" xlink:to="loc_us-gaapRelatedPartyTransactionDomain_062050" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsegmentsAxis" xlink:label="loc_us-gaapSubsegmentsAxis_dd1c58"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_c68b5f" xlink:to="loc_us-gaapSubsegmentsAxis_dd1c58" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsegmentsDomain" xlink:label="loc_us-gaapSubsegmentsDomain_e528c8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapSubsegmentsAxis_dd1c58" xlink:to="loc_us-gaapSubsegmentsDomain_e528c8" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaapPlanNameAxis_c20da0"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_c68b5f" xlink:to="loc_us-gaapPlanNameAxis_c20da0" order="40"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaapPlanNameDomain_a11df5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameAxis_c20da0" xlink:to="loc_us-gaapPlanNameDomain_a11df5" order="40"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_BoardOfDirectorsMember" xlink:label="loc_celzBoardOfDirectorsMember_b34d90"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionDomain_062050" xlink:to="loc_celzBoardOfDirectorsMember_b34d90" order="41"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_EmployeeStockOptionssMember" xlink:label="loc_celzEmployeeStockOptionssMember_052048"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapSubsegmentsDomain_e528c8" xlink:to="loc_celzEmployeeStockOptionssMember_052048" order="42" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_BlackScholesMethodMember" xlink:label="loc_celzBlackScholesMethodMember_c957bd"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapPlanNameDomain_a11df5" xlink:to="loc_celzBlackScholesMethodMember_c957bd" order="43"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_50703c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_611d08" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_50703c" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_22703c"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_611d08" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_22703c" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_0701fb"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_611d08" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_0701fb" order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_eede9e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_611d08" xlink:to="loc_us-gaapShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_eede9e" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRights" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRights_05e91f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_611d08" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRights_05e91f" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_ValueOfOptionsVest" xlink:label="loc_celzValueOfOptionsVest_c33987"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_611d08" xlink:to="loc_celzValueOfOptionsVest_c33987" order="6"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockholdersEquityDetails" xlink:title="000030 - Disclosure - STOCKHOLDERS EQUITY (Details)"> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaapStockholdersEquityNoteAbstract_d0c44e"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_286d11"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStockholdersEquityNoteAbstract_d0c44e" xlink:to="loc_us-gaapStatementTable_286d11" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_9115c7"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_286d11" xlink:to="loc_us-gaapStatementLineItems_9115c7" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis" xlink:label="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_b96244"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_286d11" xlink:to="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_b96244" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaapAntidilutiveSecuritiesNameDomain_66755b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_b96244" xlink:to="loc_us-gaapAntidilutiveSecuritiesNameDomain_66755b" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_WarrantsMember" xlink:label="loc_celzWarrantsMember_259d6f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapAntidilutiveSecuritiesNameDomain_66755b" xlink:to="loc_celzWarrantsMember_259d6f" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_a87214"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_9115c7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_a87214" order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_8a90b8"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_9115c7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_8a90b8" order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised_4377a4"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_9115c7" xlink:to="loc_us-gaapStockIssuedDuringPeriodSharesStockOptionsExercised_4377a4" order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_WeightedAverageExercisePriceOutstandingEnding" xlink:label="loc_celzWeightedAverageExercisePriceOutstandingEnding_1cbce2"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_9115c7" xlink:to="loc_celzWeightedAverageExercisePriceOutstandingEnding_1cbce2" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_b6f659"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_9115c7" xlink:to="loc_us-gaapShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_b6f659" order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/> |
| | </link:presentationLink> |
| <link:presentationLink xlink:type="extended" xlink:role="http://celz.com/role/StockholdersEquityDetailsNarrative" xlink:title="000031 - Disclosure - STOCKHOLDERS EQUITY (Details Narrative)"> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_StockholdersEquityabstract" xlink:label="loc_celzStockholdersEquityabstract_62555f"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaapStatementTable_ff41d5"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_celzStockholdersEquityabstract_62555f" xlink:to="loc_us-gaapStatementTable_ff41d5" order="100"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaapStatementLineItems_100d8a"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_ff41d5" xlink:to="loc_us-gaapStatementLineItems_100d8a" order="2000"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="loc_us-gaapRelatedPartyTransactionAxis_1d877b"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementTable_ff41d5" xlink:to="loc_us-gaapRelatedPartyTransactionAxis_1d877b" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaapRelatedPartyTransactionDomain_990f4d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionAxis_1d877b" xlink:to="loc_us-gaapRelatedPartyTransactionDomain_990f4d" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_RothCapitalPartnersMember" xlink:label="loc_celzRothCapitalPartnersMember_c1783d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapRelatedPartyTransactionDomain_990f4d" xlink:to="loc_celzRothCapitalPartnersMember_c1783d" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_DescriptionOfAmendment" xlink:label="loc_celzDescriptionOfAmendment_fcff42"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzDescriptionOfAmendment_fcff42" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:label="loc_us-gaapCommonStockCapitalSharesReservedForFutureIssuance_e3a429"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_us-gaapCommonStockCapitalSharesReservedForFutureIssuance_e3a429" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PreFundedWarrantsExercisePrice" xlink:label="loc_celzPreFundedWarrantsExercisePrice_f97c2e"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzPreFundedWarrantsExercisePrice_f97c2e" order="3"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PurchaseOfWarrantsShares" xlink:label="loc_celzPurchaseOfWarrantsShares_e37ffe"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzPurchaseOfWarrantsShares_e37ffe" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PurchaseOfPreFundedWarrantAndRelatedCommonWarrant" xlink:label="loc_celzPurchaseOfPreFundedWarrantAndRelatedCommonWarrant_98a522"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzPurchaseOfPreFundedWarrantAndRelatedCommonWarrant_98a522" order="5"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonWarrantsTerm" xlink:label="loc_celzCommonWarrantsTerm_7520f6"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzCommonWarrantsTerm_7520f6" order="6"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CommonWarrantsExercisePrice" xlink:label="loc_celzCommonWarrantsExercisePrice_ca76c1"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzCommonWarrantsExercisePrice_ca76c1" order="7"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_CombinedOfferingPriceOfPreFundedWarrantAndRelatedCommonWarrant" xlink:label="loc_celzCombinedOfferingPriceOfPreFundedWarrantAndRelatedCommonWarrant_c5527d"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzCombinedOfferingPriceOfPreFundedWarrantAndRelatedCommonWarrant_c5527d" order="8"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_PaidPlacementAgentFee" xlink:label="loc_celzPaidPlacementAgentFee_d5a3ef"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzPaidPlacementAgentFee_d5a3ef" order="9"/> |
| | <link:loc xlink:type="locator" xlink:href="celz-20220630.xsd#celz_IssuedWarrantToPurchaseSharesOfCommonStock" xlink:label="loc_celzIssuedWarrantToPurchaseSharesOfCommonStock_ed3e2f"/> |
| | <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaapStatementLineItems_100d8a" xlink:to="loc_celzIssuedWarrantToPurchaseSharesOfCommonStock_ed3e2f" order="10"/> |
| | </link:presentationLink> |
| </link:linkbase> |