SEC Info  
    Home      Search      My Interests      Help      Sign In      Please Sign In

Precigen, Inc. – ‘10-K’ for 12/31/23 – ‘EX-101.CAL’

On:  Tuesday, 3/19/24, at 4:48pm ET   ·   For:  12/31/23   ·   Accession #:  1356090-24-7   ·   File #:  1-36042

Previous ‘10-K’:  ‘10-K’ on 3/6/23 for 12/31/22   ·   Next & Latest:  ‘10-K/A’ on 4/29/24 for 12/31/23   ·   21 References:   

Find Words in Filings emoji
 
  in    Show  and   Hints

  As Of               Filer                 Filing    For·On·As Docs:Size

 3/19/24  Precigen, Inc.                    10-K       12/31/23  117:21M

Annual Report   —   Form 10-K   —   SEA’34

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   2.18M 
 3: EX-10.10    Material Contract                                   HTML     46K 
 4: EX-10.11    Material Contract                                   HTML     48K 
 2: EX-10.9     Material Contract                                   HTML     42K 
 5: EX-21.1     Subsidiaries List                                   HTML     33K 
 6: EX-23.1     Consent of Expert or Counsel                        HTML     32K 
11: EX-97       Clawback Policy re: Recovery of Erroneously         HTML     51K 
                Awarded Compensation                                             
 7: EX-31.1     Certification -- §302 - SOA'02                      HTML     37K 
 8: EX-31.2     Certification -- §302 - SOA'02                      HTML     37K 
 9: EX-32.1     Certification -- §906 - SOA'02                      HTML     34K 
10: EX-32.2     Certification -- §906 - SOA'02                      HTML     34K 
17: R1          Cover Page                                          HTML     98K 
18: R2          Audit Information                                   HTML     38K 
19: R3          Consolidated Balance Sheets                         HTML    149K 
20: R4          Consolidated Balance Sheets (Parenthetical)         HTML     46K 
21: R5          Consolidated Statements of Operations               HTML    159K 
22: R6          Consolidated Statements of Operations               HTML     46K 
                (Parenthetical)                                                  
23: R7          Condensed Consolidated Statements of Comprehensive  HTML     57K 
                Income (Loss)                                                    
24: R8          Consolidated Statements of Shareholders' Equity     HTML    130K 
25: R9          Consolidated Statements of Cash Flows               HTML    165K 
26: R10         Consolidated Statements of Cash Flows               HTML     44K 
                (Reconciliation of Cash)                                         
27: R11         Consolidated Statement of Cash Flows                HTML     34K 
                (Parenthetical)                                                  
28: R12         Organization and Basis of Presentation              HTML     43K 
29: R13         Summary of Significant Accounting Policies          HTML    107K 
30: R14         Discontinued Operations                             HTML     88K 
31: R15         Investments in Joint Ventures                       HTML     41K 
32: R16         Collaboration and Licensing Revenue                 HTML     66K 
33: R17         Short-term and Long-term Investments                HTML     58K 
34: R18         Fair Value Measurements                             HTML     61K 
35: R19         Property, Plant and Equipment, Net                  HTML     49K 
36: R20         Goodwill and Intangible Assets, Net                 HTML     59K 
37: R21         Lines of Credit and Long-Term Debt                  HTML     50K 
38: R22         Income Taxes                                        HTML    121K 
39: R23         Shareholders' Equity                                HTML     50K 
40: R24         Share-Based Payments                                HTML     90K 
41: R25         Commitments and Contingencies                       HTML     41K 
42: R26         Operating Leases                                    HTML     63K 
43: R27         Segments                                            HTML    109K 
44: R28         Defined Contribution Plans                          HTML     35K 
45: R29         Summary of Significant Accounting Policies          HTML    148K 
                (Policies)                                                       
46: R30         Summary of Significant Accounting Policies          HTML     70K 
                (Tables)                                                         
47: R31         Discontinued Operations (Tables)                    HTML     85K 
48: R32         Collaboration and Licensing Revenue (Tables)        HTML     58K 
49: R33         Short-term and Long-term Investments (Tables)       HTML     59K 
50: R34         Fair Value Measurements (Tables)                    HTML     58K 
51: R35         Property, Plant and Equipment, Net (Tables)         HTML     48K 
52: R36         Goodwill and Intangible Assets, Net (Tables)        HTML     65K 
53: R37         Lines of Credit and Long-Term Debt (Tables)         HTML     42K 
54: R38         Income Taxes (Tables)                               HTML    125K 
55: R39         Shareholders' Equity (Tables)                       HTML     40K 
56: R40         Share-Based Payments (Tables)                       HTML     89K 
57: R41         Operating Leases (Tables)                           HTML     64K 
58: R42         Segments (Tables)                                   HTML    105K 
59: R43         Organization and Basis of Presentation -            HTML     63K 
                Additional Information (Details)                                 
60: R44         Summary of Significant Accounting Policies -        HTML     75K 
                Additional Information (Details)                                 
61: R45         Summary of Significant Accounting Policies -        HTML     43K 
                Rollforward of Allowance for Credit Losses                       
                (Details)                                                        
62: R46         Summary of Significant Accounting Policies -        HTML     56K 
                Estimated Useful Lives of Property, Plant and                    
                Equipment (Details)                                              
63: R47         Summary of Significant Accounting Policies -        HTML     60K 
                Summary of Assumptions Used in Option Pricing                    
                Model (Details)                                                  
64: R48         Summary of Significant Accounting Policies -        HTML     43K 
                Potentially Dilutive Securities Excluded from                    
                Calculation of Net Loss per Share (Details)                      
65: R49         Discontinued Operations - Narrative (Details)       HTML     65K 
66: R50         Discontinued Operations - Summary of Financial      HTML     75K 
                Results for Trans Ova (Details)                                  
67: R51         Discontinued Operations - Summary of Significant    HTML     59K 
                Non-Cash Items, Investments and Purchases of                     
                Property, Plant and Equipment on Cash Flows -                    
                Trans Ova (Details)                                              
68: R52         Discontinued Operations - Summary of Financial      HTML     48K 
                Results for MBP Titan (Details)                                  
69: R53         Discontinued Operations - Summary Of Significant    HTML     43K 
                Non-Cash Items, Investments and Purchases of                     
                Property, Plant and Equipment on Cash Flows - MBP                
                Titan (Details)                                                  
70: R54         Investments in Joint Ventures - Intrexon Energy     HTML     52K 
                Partners - Additional Information (Details)                      
71: R55         Investments in Joint Ventures - Intrexon Energy     HTML     52K 
                Partners II - Additional Information (Details)                   
72: R56         Investments in Joint Ventures - Interests in        HTML     42K 
                Intrexon Energy Partners and Intrexon Energy                     
                Partners II (Details)                                            
73: R57         Collaboration and Licensing Revenue - Summarized    HTML     51K 
                Collaboration and Licensing Revenues (Details)                   
74: R58         Collaboration and Licensing Revenue - Additional    HTML     48K 
                Information (Details)                                            
75: R59         Collaboration and Licensing Revenue - Summary of    HTML     46K 
                Deferred Revenue (Details)                                       
76: R60         Short-term and Long-term Investments - Summary of   HTML     55K 
                Amortized Cost, Gross Unrealized Gains and Losses                
                and Fair Value of Investments (Details)                          
77: R61         Short-term and Long-term Investments - Narrative    HTML     35K 
                (Details)                                                        
78: R62         Fair Value Measurements - Summary of Placement in   HTML     60K 
                the Fair Value Hierarchy of Financial Assets that                
                are Measured at Fair Value on a Recurring Basis                  
                (Details)                                                        
79: R63         Fair Value Measurements - Additional Information    HTML     39K 
                (Details)                                                        
80: R64         Property, Plant and Equipment, Net - Schedule of    HTML     57K 
                Property, Plant and Equipment (Details)                          
81: R65         Property, Plant and Equipment, Net - Additional     HTML     40K 
                Information (Details)                                            
82: R66         Goodwill and Intangible Assets, Net - Schedule of   HTML     45K 
                Changes in Carrying Amount of Goodwill (Details)                 
83: R67         Goodwill and Intangible Assets, Net - Additional    HTML     52K 
                Information (Details)                                            
84: R68         Goodwill and Intangible Assets, Net - Schedule of   HTML     47K 
                Intangible Assets (Details)                                      
85: R69         Goodwill and Intangible Assets, Net - Schedule of   HTML     48K 
                Definite-Lived Intangible Assets, Estimated Future               
                Amortization Expense (Details)                                   
86: R70         Lines of Credit and Long-Term Debt - Lines of       HTML     44K 
                Credit - Additional Information (Details)                        
87: R71         Lines of Credit and Long-Term Debt - Short-Term     HTML     67K 
                Debt and Convertible Debt - Additional Information               
                (Details)                                                        
88: R72         Lines of Credit and Long-Term Debt - Components of  HTML     48K 
                Interest Expense (Details)                                       
89: R73         Income Taxes - Components of Loss Before Income     HTML     42K 
                Taxes (Details)                                                  
90: R74         Income Taxes - Components of Income Tax Benefit     HTML     53K 
                (Details)                                                        
91: R75         Income Taxes - Schedule of Effective Income Tax     HTML     61K 
                Rate Reconciliation (Details)                                    
92: R76         Income Taxes - Schedule of Deferred Tax Assets and  HTML     75K 
                Liabilities (Details)                                            
93: R77         Income Taxes - Summary of Valuation Allowance       HTML     47K 
                (Details)                                                        
94: R78         Income Taxes - Additional Information (Details)     HTML     48K 
95: R79         Shareholders' Equity - Additional Information       HTML     54K 
                (Details)                                                        
96: R80         Shareholders' Equity - Components of Accumulated    HTML     54K 
                Other Comprehensive Income (Loss) (Details)                      
97: R81         Share-Based Payments - Schedule of Stock-based      HTML     45K 
                Compensation Expense (Details)                                   
98: R82         Share-Based Payments - Additional Information       HTML     89K 
                (Details)                                                        
99: R83         Share-Based Payments - Schedule of Stock Option     HTML     74K 
                Activity (Details)                                               
100: R84         Share-Based Payments - Schedule of Restricted       HTML     63K  
                Stock Unit Activity (Details)                                    
101: R85         Commitments and Contingencies - Contingencies -     HTML     42K  
                Additional Information (Details)                                 
102: R86         Operating Leases - Additional Information           HTML     40K  
                (Details)                                                        
103: R87         Operating Leases - Components of Lease Costs        HTML     41K  
                (Details)                                                        
104: R88         Operating Leases - Maturities of Lease Liabilities  HTML     56K  
                (Details)                                                        
105: R89         Operating Leases - Lease Terms and Discount Rates   HTML     37K  
                (Details)                                                        
106: R90         Operating Leases - Other Information (Details)      HTML     37K  
107: R91         Segments - Adjusted EBITDA by Reportable Segment    HTML     40K  
                (Details)                                                        
108: R92         Segments - Reconciliation of Net Loss Before        HTML     85K  
                Income Taxes (Details)                                           
109: R93         Segments - Revenues by Reportable Segment           HTML     43K  
                (Details)                                                        
110: R94         Segments - Additional Information (Details)         HTML     50K  
111: R95         Segments - Goodwill (Details)                       HTML     51K  
112: R96         Defined Contribution Plans - Additional             HTML     34K  
                Information (Details)                                            
114: XML         IDEA XML File -- Filing Summary                      XML    216K  
117: XML         XBRL Instance -- pgen-20231231_htm                   XML   2.17M  
113: EXCEL       IDEA Workbook of Financial Report Info              XLSX    206K  
13: EX-101.CAL  XBRL Calculations -- pgen-20231231_cal               XML    286K 
14: EX-101.DEF  XBRL Definitions -- pgen-20231231_def                XML   1.00M 
15: EX-101.LAB  XBRL Labels -- pgen-20231231_lab                     XML   1.93M 
16: EX-101.PRE  XBRL Presentations -- pgen-20231231_pre              XML   1.46M 
12: EX-101.SCH  XBRL Schema -- pgen-20231231                         XSD    221K 
115: JSON        XBRL Instance as JSON Data -- MetaLinks              648±   986K  
116: ZIP         XBRL Zipped Folder -- 0001356090-24-000007-xbrl      Zip   3.11M  


‘EX-101.CAL’   —   XBRL Calculations — pgen-20231231_cal


This Exhibit is an XBRL File.


                                                                                                                                                                                
<?xml version="1.0" encoding="windows-1252"?>
<!-- XBRL Document Created with the Workiva Platform -->
<!-- Copyright 2024 Workiva -->
<!-- r:63d4ae04-22fd-40c6-a830-6ea46db1b3a9,g:43913839-4ef2-4573-81b4-ab4bdaf9db52 -->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
<link:roleRef roleURI="http://www.dna.com/role/ConsolidatedBalanceSheets" xlink:type="simple" xlink:href="pgen-20231231.xsd#ConsolidatedBalanceSheets"/>
<link:calculationLink xlink:role="http://www.dna.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_3f21a570-976e-410c-be6b-8766113fbbc4" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Assets"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_6632b4c3-6636-48ac-a319-dad0861221d2" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_3f21a570-976e-410c-be6b-8766113fbbc4" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_6632b4c3-6636-48ac-a319-dad0861221d2" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_515998f4-896b-400d-ab00-0b7ae4ac56df" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_3f21a570-976e-410c-be6b-8766113fbbc4" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_515998f4-896b-400d-ab00-0b7ae4ac56df" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_e4b86c64-5215-4f46-8b89-8b1e3778860c" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_3f21a570-976e-410c-be6b-8766113fbbc4" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_e4b86c64-5215-4f46-8b89-8b1e3778860c" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_034f057b-734d-47bf-9978-58aa1bc2dd0a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Goodwill"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_3f21a570-976e-410c-be6b-8766113fbbc4" xlink:to="loc_us-gaap_Goodwill_034f057b-734d-47bf-9978-58aa1bc2dd0a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_f4f8340c-433a-41b4-a754-71d4ede18d4a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAssetsNoncurrent"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_3f21a570-976e-410c-be6b-8766113fbbc4" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_f4f8340c-433a-41b4-a754-71d4ede18d4a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_3034ef3b-0a6e-4315-87fb-f18f93eb38cf" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsCurrent"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_3f21a570-976e-410c-be6b-8766113fbbc4" xlink:to="loc_us-gaap_AssetsCurrent_3034ef3b-0a6e-4315-87fb-f18f93eb38cf" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesCurrent"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermBorrowings_4296c2b3-d524-4577-8d57-1ac2445b4769" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShortTermBorrowings"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:to="loc_us-gaap_ShortTermBorrowings_4296c2b3-d524-4577-8d57-1ac2445b4769" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_f900b141-db19-472e-a190-480e72a2f3a6" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_f900b141-db19-472e-a190-480e72a2f3a6" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_SettlementAndIndemnificationAccrualsCurrent_1a6d3474-fd0b-4c49-9cda-5d9110cdb94b" xlink:href="pgen-20231231.xsd#pgen_SettlementAndIndemnificationAccrualsCurrent"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:to="loc_pgen_SettlementAndIndemnificationAccrualsCurrent_1a6d3474-fd0b-4c49-9cda-5d9110cdb94b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_df2d20fa-a7b7-4bcd-a454-46d7e5a7c32c" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_df2d20fa-a7b7-4bcd-a454-46d7e5a7c32c" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_b701a364-88c6-4322-9452-f0531570a372" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsPayableCurrent"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:to="loc_us-gaap_AccountsPayableCurrent_b701a364-88c6-4322-9452-f0531570a372" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_5085dccf-be5a-4804-8277-97c4f4e5c209" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_5085dccf-be5a-4804-8277-97c4f4e5c209" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_65989617-4c47-44a5-9e63-41120b3cc92b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
<link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_699fb131-50c2-4df3-b909-1debe1ca7da7" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_65989617-4c47-44a5-9e63-41120b3cc92b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_c17890b1-97ab-4c37-b67a-47861bcc211d" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AssetsCurrent"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_9046e380-dbac-4ac2-baae-50431b8401c2" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccountsReceivableNetCurrent"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_c17890b1-97ab-4c37-b67a-47861bcc211d" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_9046e380-dbac-4ac2-baae-50431b8401c2" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashCurrent_3290b51d-54c1-49f5-b157-6668fd1ee19c" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RestrictedCashCurrent"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_c17890b1-97ab-4c37-b67a-47861bcc211d" xlink:to="loc_us-gaap_RestrictedCashCurrent_3290b51d-54c1-49f5-b157-6668fd1ee19c" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivablesNetCurrent_65b26115-083a-483c-bbb7-13080e2dea1a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherReceivablesNetCurrent"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_c17890b1-97ab-4c37-b67a-47861bcc211d" xlink:to="loc_us-gaap_OtherReceivablesNetCurrent_65b26115-083a-483c-bbb7-13080e2dea1a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_b78cb7fe-9b16-4ffd-97df-0549e483925c" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_c17890b1-97ab-4c37-b67a-47861bcc211d" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_b78cb7fe-9b16-4ffd-97df-0549e483925c" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_31c94fdc-c473-47a5-8b16-51a894f4a303" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_c17890b1-97ab-4c37-b67a-47861bcc211d" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_31c94fdc-c473-47a5-8b16-51a894f4a303" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermInvestments_fd368185-1789-4b74-82c6-88158ff66673" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShortTermInvestments"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_c17890b1-97ab-4c37-b67a-47861bcc211d" xlink:to="loc_us-gaap_ShortTermInvestments_fd368185-1789-4b74-82c6-88158ff66673" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_0f99c4e8-8f39-465c-936b-6db5858d21d5" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Liabilities"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_418144f3-25ac-4db7-ad56-870a71c45a74" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_0f99c4e8-8f39-465c-936b-6db5858d21d5" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_418144f3-25ac-4db7-ad56-870a71c45a74" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_ff73e693-8332-4774-8fdb-a56edf8c81cd" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_0f99c4e8-8f39-465c-936b-6db5858d21d5" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_ff73e693-8332-4774-8fdb-a56edf8c81cd" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_eff67377-97c1-4dc8-8e0c-cf364effeb13" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_0f99c4e8-8f39-465c-936b-6db5858d21d5" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_eff67377-97c1-4dc8-8e0c-cf364effeb13" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_0b154c84-b225-4ce8-9132-2cf4d09b9d6a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesCurrent"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_0f99c4e8-8f39-465c-936b-6db5858d21d5" xlink:to="loc_us-gaap_LiabilitiesCurrent_0b154c84-b225-4ce8-9132-2cf4d09b9d6a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_4a6e23da-9ddc-4fda-92ce-078866f8b189" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_73fa28e0-ab93-4872-8167-ed8733e173ef" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_Liabilities"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_4a6e23da-9ddc-4fda-92ce-078866f8b189" xlink:to="loc_us-gaap_Liabilities_73fa28e0-ab93-4872-8167-ed8733e173ef" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_cbfcd00e-5027-4aeb-857d-fcfed8264efe" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_4a6e23da-9ddc-4fda-92ce-078866f8b189" xlink:to="loc_us-gaap_StockholdersEquity_cbfcd00e-5027-4aeb-857d-fcfed8264efe" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_0ae64fcd-cedd-441d-98a3-99a87f56befe" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommitmentsAndContingencies"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_4a6e23da-9ddc-4fda-92ce-078866f8b189" xlink:to="loc_us-gaap_CommitmentsAndContingencies_0ae64fcd-cedd-441d-98a3-99a87f56befe" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_af05f1b8-7e68-45d9-94d3-9e525c380a65" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StockholdersEquity"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValueOutstanding_fbaccbcb-0880-4218-9472-a4e174d60a7b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockValueOutstanding"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_af05f1b8-7e68-45d9-94d3-9e525c380a65" xlink:to="loc_us-gaap_CommonStockValueOutstanding_fbaccbcb-0880-4218-9472-a4e174d60a7b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_cb07e65b-1e8f-4465-9d23-9d2a7516f180" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AdditionalPaidInCapital"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_af05f1b8-7e68-45d9-94d3-9e525c380a65" xlink:to="loc_us-gaap_AdditionalPaidInCapital_cb07e65b-1e8f-4465-9d23-9d2a7516f180" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_283db554-67d3-4872-930b-9ae359f255f9" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_af05f1b8-7e68-45d9-94d3-9e525c380a65" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_283db554-67d3-4872-930b-9ae359f255f9" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_6c830daa-28b0-4d6f-942a-35a09ec80d46" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_af05f1b8-7e68-45d9-94d3-9e525c380a65" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_6c830daa-28b0-4d6f-942a-35a09ec80d46" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/ConsolidatedStatementsofOperations" xlink:type="simple" xlink:href="pgen-20231231.xsd#ConsolidatedStatementsofOperations"/>
<link:calculationLink xlink:role="http://www.dna.com/role/ConsolidatedStatementsofOperations" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_b4ac2f02-a953-4cf5-9fec-776b02114c2d" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareDiluted"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_fdb4e566-ad12-48c5-9785-274a180bc96a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EarningsPerShareDiluted_b4ac2f02-a953-4cf5-9fec-776b02114c2d" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_fdb4e566-ad12-48c5-9785-274a180bc96a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare_e7290b7b-fa58-4212-aaa3-7f18954f9f35" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EarningsPerShareDiluted_b4ac2f02-a953-4cf5-9fec-776b02114c2d" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare_e7290b7b-fa58-4212-aaa3-7f18954f9f35" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_7cd307e9-4396-4252-964f-3157297225e4" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_6d5f6dc8-bccc-4a8b-8b30-4f06ce4fe033" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_7cd307e9-4396-4252-964f-3157297225e4" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_6d5f6dc8-bccc-4a8b-8b30-4f06ce4fe033" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_405ee282-d1f6-40a9-a4c2-1f2367154e51" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_7cd307e9-4396-4252-964f-3157297225e4" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_405ee282-d1f6-40a9-a4c2-1f2367154e51" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_071ec69c-1d42-4fb4-8ffd-fe93d13249f5" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EarningsPerShareBasic"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_d6fd12db-0393-4a6b-b4ef-71c5be5ccfa8" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EarningsPerShareBasic_071ec69c-1d42-4fb4-8ffd-fe93d13249f5" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_d6fd12db-0393-4a6b-b4ef-71c5be5ccfa8" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare_a4848a49-9d03-4c01-a5bf-3ea422081ffc" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EarningsPerShareBasic_071ec69c-1d42-4fb4-8ffd-fe93d13249f5" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare_a4848a49-9d03-4c01-a5bf-3ea422081ffc" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_77fd1873-d1b7-4642-a8e2-2641bf3768dd" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpenses"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetImpairmentCharges_5a2c48fc-6695-4872-b458-0774a9d6ecc5" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAssetImpairmentCharges"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_77fd1873-d1b7-4642-a8e2-2641bf3768dd" xlink:to="loc_us-gaap_OtherAssetImpairmentCharges_5a2c48fc-6695-4872-b458-0774a9d6ecc5" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_4833b9d4-ebd8-4d10-ab7d-ee040b6459a3" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_77fd1873-d1b7-4642-a8e2-2641bf3768dd" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_4833b9d4-ebd8-4d10-ab7d-ee040b6459a3" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_2ea204e2-93a2-4eac-99ab-49964e5e3d97" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_77fd1873-d1b7-4642-a8e2-2641bf3768dd" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_2ea204e2-93a2-4eac-99ab-49964e5e3d97" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_7b6c432f-c619-4034-96ea-95c288c11fd3" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_77fd1873-d1b7-4642-a8e2-2641bf3768dd" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_7b6c432f-c619-4034-96ea-95c288c11fd3" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_543c253e-d863-45ba-9f94-8a9356288729" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GoodwillImpairmentLoss"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_77fd1873-d1b7-4642-a8e2-2641bf3768dd" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_543c253e-d863-45ba-9f94-8a9356288729" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_8557f481-f0ec-4562-b3ce-c7e6bbe4ecb6" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingIncomeLoss"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_d567fa2d-12a7-44f9-b6be-eaebcbadaf8b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_8557f481-f0ec-4562-b3ce-c7e6bbe4ecb6" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_d567fa2d-12a7-44f9-b6be-eaebcbadaf8b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_17e56f7f-e997-455c-b5cb-6acf1cd978c8" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingExpenses"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_8557f481-f0ec-4562-b3ce-c7e6bbe4ecb6" xlink:to="loc_us-gaap_OperatingExpenses_17e56f7f-e997-455c-b5cb-6acf1cd978c8" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_6cc77328-8560-44fa-b09d-e36ed6644cd9" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_92c5bd36-beb6-4544-9ede-182c45ccc540" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingIncomeLoss"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_6cc77328-8560-44fa-b09d-e36ed6644cd9" xlink:to="loc_us-gaap_OperatingIncomeLoss_92c5bd36-beb6-4544-9ede-182c45ccc540" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_69534bc8-2738-423f-bbad-ceed2cfc9972" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpense"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_6cc77328-8560-44fa-b09d-e36ed6644cd9" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_69534bc8-2738-423f-bbad-ceed2cfc9972" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_6dc17bfb-11e7-46bb-9e17-1b5f45f5d450" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_6cc77328-8560-44fa-b09d-e36ed6644cd9" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_6dc17bfb-11e7-46bb-9e17-1b5f45f5d450" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_23fd865c-5aa7-4dcf-9393-1a65609cd04f" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_a5bb4265-f3ea-4f56-af3d-b27767616bfe" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_23fd865c-5aa7-4dcf-9393-1a65609cd04f" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_a5bb4265-f3ea-4f56-af3d-b27767616bfe" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_5c5d8869-4ab1-4a4f-bc9e-a6d7f810f0db" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_23fd865c-5aa7-4dcf-9393-1a65609cd04f" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_5c5d8869-4ab1-4a4f-bc9e-a6d7f810f0db" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_a573437c-54b9-4835-9655-0163537a8cc4" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NonoperatingIncomeExpense"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_9492e8d7-29d1-459e-833f-5288760f6219" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestExpense"/>
<link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NonoperatingIncomeExpense_a573437c-54b9-4835-9655-0163537a8cc4" xlink:to="loc_us-gaap_InterestExpense_9492e8d7-29d1-459e-833f-5288760f6219" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeNonoperating_7ffc89a7-2d1b-435b-b071-ebdfe71d3b5b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InvestmentIncomeNonoperating"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NonoperatingIncomeExpense_a573437c-54b9-4835-9655-0163537a8cc4" xlink:to="loc_us-gaap_InvestmentIncomeNonoperating_7ffc89a7-2d1b-435b-b071-ebdfe71d3b5b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_1ae9aeba-c9f3-4ffd-b0e1-0ca067bc82cc" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NonoperatingIncomeExpense_a573437c-54b9-4835-9655-0163537a8cc4" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_1ae9aeba-c9f3-4ffd-b0e1-0ca067bc82cc" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/CondensedConsolidatedStatementsofComprehensiveIncomeloss" xlink:type="simple" xlink:href="pgen-20231231.xsd#CondensedConsolidatedStatementsofComprehensiveIncomeloss"/>
<link:calculationLink xlink:role="http://www.dna.com/role/CondensedConsolidatedStatementsofComprehensiveIncomeloss" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_f29146e7-55fe-4935-9ea8-3df9c2e5033c" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_e24dd353-398a-4852-83c5-f856d327d023" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f29146e7-55fe-4935-9ea8-3df9c2e5033c" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_e24dd353-398a-4852-83c5-f856d327d023" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_8035e8f0-6f22-4ec7-9578-571448efffd8" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f29146e7-55fe-4935-9ea8-3df9c2e5033c" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_8035e8f0-6f22-4ec7-9578-571448efffd8" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_e3f5b392-1ba2-4d29-96a2-729f4416395c" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f29146e7-55fe-4935-9ea8-3df9c2e5033c" xlink:to="loc_us-gaap_NetIncomeLoss_e3f5b392-1ba2-4d29-96a2-729f4416395c" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/ConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="pgen-20231231.xsd#ConsolidatedStatementsofCashFlows"/>
<link:calculationLink xlink:role="http://www.dna.com/role/ConsolidatedStatementsofCashFlows" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_43887215-4848-42ed-b262-a016659d2978" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_43887215-4848-42ed-b262-a016659d2978" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_0fa17e02-bb6c-48dd-a0dd-c2093f6ae040" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_0fa17e02-bb6c-48dd-a0dd-c2093f6ae040" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_2bc5906a-dd06-4452-9c5a-b1fa8e3cea3b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_2bc5906a-dd06-4452-9c5a-b1fa8e3cea3b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_fd48600d-ad21-4c48-8ba3-9e44fb6e1003" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_fd48600d-ad21-4c48-8ba3-9e44fb6e1003" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_fabe75d1-9fb4-42b8-9e42-fe6f584dff2f" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_fabe75d1-9fb4-42b8-9e42-fe6f584dff2f" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_DisposalGroupIncludingDiscontinuedOperationGainLossonDisposal_5cf5708c-5926-4275-82c5-2760d156cbb3" xlink:href="pgen-20231231.xsd#pgen_DisposalGroupIncludingDiscontinuedOperationGainLossonDisposal"/>
<link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_pgen_DisposalGroupIncludingDiscontinuedOperationGainLossonDisposal_5cf5708c-5926-4275-82c5-2760d156cbb3" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_6db30a89-b4a1-48ee-b43a-cdc8fccfe9be" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities"/>
<link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_6db30a89-b4a1-48ee-b43a-cdc8fccfe9be" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_SharesIssuedDuringPeriodValueIssuedForServicesExpense_d6b7a1b6-bc7a-456c-830d-81b573bdbede" xlink:href="pgen-20231231.xsd#pgen_SharesIssuedDuringPeriodValueIssuedForServicesExpense"/>
<link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_pgen_SharesIssuedDuringPeriodValueIssuedForServicesExpense_d6b7a1b6-bc7a-456c-830d-81b573bdbede" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherReceivables_a3099350-06df-45a6-8198-9a3c9300de9b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOtherReceivables"/>
<link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherReceivables_a3099350-06df-45a6-8198-9a3c9300de9b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_937b6449-242a-4295-8315-2254146b4a97" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
<link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_937b6449-242a-4295-8315-2254146b4a97" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetImpairmentCharges_666f4e7d-2a63-4dc7-b14d-82fbe10e8d66" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherAssetImpairmentCharges"/>
<link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_OtherAssetImpairmentCharges_666f4e7d-2a63-4dc7-b14d-82fbe10e8d66" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSaleOfOtherAssets_53d7636f-f379-4390-aff4-f31163fabbf1" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GainLossOnSaleOfOtherAssets"/>
<link:calculationArc order="12" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_GainLossOnSaleOfOtherAssets_53d7636f-f379-4390-aff4-f31163fabbf1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_ad0402e6-3f23-4fb6-bef4-b77020f53149" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OtherNoncashIncomeExpense"/>
<link:calculationArc order="13" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_ad0402e6-3f23-4fb6-bef4-b77020f53149" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_369329c8-0015-4f01-a500-05df6d046622" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
<link:calculationArc order="14" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_369329c8-0015-4f01-a500-05df6d046622" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_db9c4170-2ac8-4c02-897c-9330737a5048" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GoodwillImpairmentLoss"/>
<link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_db9c4170-2ac8-4c02-897c-9330737a5048" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_48e86fef-0931-4b67-bcca-a16faad1b1be" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
<link:calculationArc order="16" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_48e86fef-0931-4b67-bcca-a16faad1b1be" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherAccruedLiabilities_42e73eb0-c31d-4fb1-8c20-b98121baeab0" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOtherAccruedLiabilities"/>
<link:calculationArc order="17" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherAccruedLiabilities_42e73eb0-c31d-4fb1-8c20-b98121baeab0" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_18b0b875-54c1-4af0-a111-50b5fddfdbdb" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments"/>
<link:calculationArc order="18" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_18b0b875-54c1-4af0-a111-50b5fddfdbdb" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_4ccc6a9a-5c51-4271-8f20-c08318c6b80f" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities"/>
<link:calculationArc order="19" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_4ccc6a9a-5c51-4271-8f20-c08318c6b80f" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingLeaseLiability_f887f154-5cbf-4ce8-97b7-26e294895da1" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInOperatingLeaseLiability"/>
<link:calculationArc order="20" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingLeaseLiability_f887f154-5cbf-4ce8-97b7-26e294895da1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_bb9b66e4-012c-436d-864d-95bf288b712a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShareBasedCompensation"/>
<link:calculationArc order="21" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_ShareBasedCompensation_bb9b66e4-012c-436d-864d-95bf288b712a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_dbfe3f93-16e3-4f96-aac8-0124daac42ed" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetIncomeLoss"/>
<link:calculationArc order="22" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_NetIncomeLoss_dbfe3f93-16e3-4f96-aac8-0124daac42ed" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableTrade_099e1dd8-5d5a-4e44-8096-7213ecbc0447" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccountsPayableTrade"/>
<link:calculationArc order="23" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableTrade_099e1dd8-5d5a-4e44-8096-7213ecbc0447" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_107369a3-4f82-4c82-a77e-c6661c2e0d9a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
<link:calculationArc order="24" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_107369a3-4f82-4c82-a77e-c6661c2e0d9a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_NoncashGainLossOnTerminationOfLease_14bc9b99-4f7f-467c-858c-b6f780e1e387" xlink:href="pgen-20231231.xsd#pgen_NoncashGainLossOnTerminationOfLease"/>
<link:calculationArc order="25" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_pgen_NoncashGainLossOnTerminationOfLease_14bc9b99-4f7f-467c-858c-b6f780e1e387" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_4e0389cb-08ae-422e-967a-b80a33c37c07" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
<link:calculationArc order="26" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_4e0389cb-08ae-422e-967a-b80a33c37c07" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_IncreaseDecreaseSettlementAndIdentificationAccruals_2547a99d-0971-4df2-b003-99a3812191f1" xlink:href="pgen-20231231.xsd#pgen_IncreaseDecreaseSettlementAndIdentificationAccruals"/>
<link:calculationArc order="27" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f0a8f6fc-1d0b-4265-9f40-e2286e70acfd" xlink:to="loc_pgen_IncreaseDecreaseSettlementAndIdentificationAccruals_2547a99d-0971-4df2-b003-99a3812191f1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_e344aca4-c653-48a0-8a91-4c63b1b35049" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_9a80414a-eff6-4f31-b2d8-1ccaa793bde0" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_e344aca4-c653-48a0-8a91-4c63b1b35049" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_9a80414a-eff6-4f31-b2d8-1ccaa793bde0" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_18c13317-9ad9-456e-a7ad-ebd3213dc3a6" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_e344aca4-c653-48a0-8a91-4c63b1b35049" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_18c13317-9ad9-456e-a7ad-ebd3213dc3a6" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_b8a58a92-7d56-4083-b8dd-9dce82a89bf8" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_e344aca4-c653-48a0-8a91-4c63b1b35049" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_b8a58a92-7d56-4083-b8dd-9dce82a89bf8" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_fd9ea0db-5a50-42b5-9554-2b0d0d544dbd" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_e344aca4-c653-48a0-8a91-4c63b1b35049" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_fd9ea0db-5a50-42b5-9554-2b0d0d544dbd" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e6701b16-df54-42dd-9b5e-97cafe8410be" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities_1c7a2e53-c18b-402f-b6d4-f38366bcf062" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e6701b16-df54-42dd-9b5e-97cafe8410be" xlink:to="loc_us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities_1c7a2e53-c18b-402f-b6d4-f38366bcf062" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireInvestments_1ed10aac-05b3-489c-9bfd-c5b87237a779" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PaymentsToAcquireInvestments"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e6701b16-df54-42dd-9b5e-97cafe8410be" xlink:to="loc_us-gaap_PaymentsToAcquireInvestments_1ed10aac-05b3-489c-9bfd-c5b87237a779" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfOtherAssetsInvestingActivities_e03e5c49-ed67-49c1-b1e1-802fb4163d02" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromSaleOfOtherAssetsInvestingActivities"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e6701b16-df54-42dd-9b5e-97cafe8410be" xlink:to="loc_us-gaap_ProceedsFromSaleOfOtherAssetsInvestingActivities_e03e5c49-ed67-49c1-b1e1-802fb4163d02" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_aabeda0f-ba79-4b99-b0d4-f272927b6b8a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e6701b16-df54-42dd-9b5e-97cafe8410be" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_aabeda0f-ba79-4b99-b0d4-f272927b6b8a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_a519b25a-fb9a-480e-a897-1bc93d01b92d" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
<link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e6701b16-df54-42dd-9b5e-97cafe8410be" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_a519b25a-fb9a-480e-a897-1bc93d01b92d" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromCollectionOfNotesReceivable_cd1029dc-84ae-4258-8921-0be9b4d0e1d8" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ProceedsFromCollectionOfNotesReceivable"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e6701b16-df54-42dd-9b5e-97cafe8410be" xlink:to="loc_us-gaap_ProceedsFromCollectionOfNotesReceivable_cd1029dc-84ae-4258-8921-0be9b4d0e1d8" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_4391dded-9dbe-4d79-a19b-041f0e50750b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_ProceedsfromStockOptionsandWarrantsExercised_ef2d80cb-851a-4416-8f50-30412e2bffeb" xlink:href="pgen-20231231.xsd#pgen_ProceedsfromStockOptionsandWarrantsExercised"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_4391dded-9dbe-4d79-a19b-041f0e50750b" xlink:to="loc_pgen_ProceedsfromStockOptionsandWarrantsExercised_ef2d80cb-851a-4416-8f50-30412e2bffeb" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_ProceedsfromIssuanceofCommonStockandWarrantsNet_f31d03db-90ec-49cd-8211-948566ce98f1" xlink:href="pgen-20231231.xsd#pgen_ProceedsfromIssuanceofCommonStockandWarrantsNet"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_4391dded-9dbe-4d79-a19b-041f0e50750b" xlink:to="loc_pgen_ProceedsfromIssuanceofCommonStockandWarrantsNet_f31d03db-90ec-49cd-8211-948566ce98f1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_0a5479d8-fd19-47b2-bcf2-1c95e27f38ed" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
<link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_4391dded-9dbe-4d79-a19b-041f0e50750b" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_0a5479d8-fd19-47b2-bcf2-1c95e27f38ed" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/ConsolidatedStatementsofCashFlowsReconciliationofCash" xlink:type="simple" xlink:href="pgen-20231231.xsd#ConsolidatedStatementsofCashFlowsReconciliationofCash"/>
<link:calculationLink xlink:role="http://www.dna.com/role/ConsolidatedStatementsofCashFlowsReconciliationofCash" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_1a450e65-84f3-4923-9554-ae2f574b5840" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_71a3f179-e404-49ba-9ae2-770dfb8b1aa1" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_1a450e65-84f3-4923-9554-ae2f574b5840" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_71a3f179-e404-49ba-9ae2-770dfb8b1aa1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_ffe914c1-2fbf-487d-9aa6-92edca16e37e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_1a450e65-84f3-4923-9554-ae2f574b5840" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_ffe914c1-2fbf-487d-9aa6-92edca16e37e" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_319a037b-4883-4b28-965d-c125d614d7d6" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_1a450e65-84f3-4923-9554-ae2f574b5840" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_319a037b-4883-4b28-965d-c125d614d7d6" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/DiscontinuedOperationsSummaryofFinancialResultsforTransOvaDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#DiscontinuedOperationsSummaryofFinancialResultsforTransOvaDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/DiscontinuedOperationsSummaryofFinancialResultsforTransOvaDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_57676370-0307-4348-b5ba-d9e05766287d" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_a4aee46a-aec1-4af8-beaf-6a8863873e99" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_57676370-0307-4348-b5ba-d9e05766287d" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_a4aee46a-aec1-4af8-beaf-6a8863873e99" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_33bf2157-74ba-4f13-9ef3-4562f91db9af" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_57676370-0307-4348-b5ba-d9e05766287d" xlink:to="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_33bf2157-74ba-4f13-9ef3-4562f91db9af" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_c66fce2e-c6bf-4e9f-b24d-35fc00de723e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DiscontinuedOperationGainLossFromDisposalOfDiscontinuedOperationBeforeIncomeTax_3a61c2b6-74a7-49a8-878f-d68874b47307" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DiscontinuedOperationGainLossFromDisposalOfDiscontinuedOperationBeforeIncomeTax"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_c66fce2e-c6bf-4e9f-b24d-35fc00de723e" xlink:to="loc_us-gaap_DiscontinuedOperationGainLossFromDisposalOfDiscontinuedOperationBeforeIncomeTax_3a61c2b6-74a7-49a8-878f-d68874b47307" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherIncome_ca3b4bf1-2cde-4db1-8b45-b5268f56dd43" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherIncome"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_c66fce2e-c6bf-4e9f-b24d-35fc00de723e" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherIncome_ca3b4bf1-2cde-4db1-8b45-b5268f56dd43" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_7064d32a-e050-46c3-96f1-9a2213ebd529" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_c66fce2e-c6bf-4e9f-b24d-35fc00de723e" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_7064d32a-e050-46c3-96f1-9a2213ebd529" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingExpense_a70a7642-c0b8-4d1f-b3b4-c7aa71634a7a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingExpense"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationGeneralAndAdministrativeExpense_c00a5296-fdfc-4903-89fe-cbe853f750d8" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationGeneralAndAdministrativeExpense"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingExpense_a70a7642-c0b8-4d1f-b3b4-c7aa71634a7a" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationGeneralAndAdministrativeExpense_c00a5296-fdfc-4903-89fe-cbe853f750d8" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_DisposalGroupIncludingDiscontinuedOperationResearchAndDevelopment_3805b16a-d477-44ac-8f54-6c4e28b3cd6e" xlink:href="pgen-20231231.xsd#pgen_DisposalGroupIncludingDiscontinuedOperationResearchAndDevelopment"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingExpense_a70a7642-c0b8-4d1f-b3b4-c7aa71634a7a" xlink:to="loc_pgen_DisposalGroupIncludingDiscontinuedOperationResearchAndDevelopment_3805b16a-d477-44ac-8f54-6c4e28b3cd6e" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_DisposalGroupIncludingDiscontinuedOperationCostsOfServices_72eff325-6c4a-4ab3-be49-b74982e09954" xlink:href="pgen-20231231.xsd#pgen_DisposalGroupIncludingDiscontinuedOperationCostsOfServices"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingExpense_a70a7642-c0b8-4d1f-b3b4-c7aa71634a7a" xlink:to="loc_pgen_DisposalGroupIncludingDiscontinuedOperationCostsOfServices_72eff325-6c4a-4ab3-be49-b74982e09954" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCostsOfGoodsSold_d14940a4-fe94-492a-9610-ebf0064afbf4" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationCostsOfGoodsSold"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingExpense_a70a7642-c0b8-4d1f-b3b4-c7aa71634a7a" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCostsOfGoodsSold_d14940a4-fe94-492a-9610-ebf0064afbf4" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/CollaborationandLicensingRevenueSummaryofDeferredRevenueDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#CollaborationandLicensingRevenueSummaryofDeferredRevenueDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/CollaborationandLicensingRevenueSummaryofDeferredRevenueDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiability_76315c0c-441b-4268-9e8a-2ce451d24cff" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ContractWithCustomerLiability"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_6912a7db-9371-4369-a416-485e97fc9f5a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ContractWithCustomerLiability_76315c0c-441b-4268-9e8a-2ce451d24cff" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_6912a7db-9371-4369-a416-485e97fc9f5a" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_d7227551-7d13-4449-b962-f4ff466f13b0" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ContractWithCustomerLiability_76315c0c-441b-4268-9e8a-2ce451d24cff" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_d7227551-7d13-4449-b962-f4ff466f13b0" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/ShorttermandLongtermInvestmentsSummaryofAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentsDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#ShorttermandLongtermInvestmentsSummaryofAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentsDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/ShorttermandLongtermInvestmentsSummaryofAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_f7fd264b-1e08-4406-b363-b68547c58a13" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_dc3c633e-e38b-4ed9-8cae-6a0b09215d37" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
<link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_f7fd264b-1e08-4406-b363-b68547c58a13" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_dc3c633e-e38b-4ed9-8cae-6a0b09215d37" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_52847896-bf49-4404-98a8-ab68f33e890e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_f7fd264b-1e08-4406-b363-b68547c58a13" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_52847896-bf49-4404-98a8-ab68f33e890e" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d8cda147-bd33-42c4-a50f-e24b61de8bb0" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_f7fd264b-1e08-4406-b363-b68547c58a13" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d8cda147-bd33-42c4-a50f-e24b61de8bb0" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/PropertyPlantandEquipmentNetScheduleofPropertyPlantandEquipmentDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#PropertyPlantandEquipmentNetScheduleofPropertyPlantandEquipmentDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/PropertyPlantandEquipmentNetScheduleofPropertyPlantandEquipmentDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_67c01ca9-887a-4e26-b43e-b8a91107216f" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_d0788135-e842-475e-8f66-9085d6d5c0dd" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_67c01ca9-887a-4e26-b43e-b8a91107216f" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_d0788135-e842-475e-8f66-9085d6d5c0dd" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_96040d2f-66c7-4bd1-a53e-a135f9689574" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_67c01ca9-887a-4e26-b43e-b8a91107216f" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_96040d2f-66c7-4bd1-a53e-a135f9689574" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LandAndLandImprovements_862faaa3-dca8-43ff-9aef-227c1cc3c2a3" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LandAndLandImprovements"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_us-gaap_LandAndLandImprovements_862faaa3-dca8-43ff-9aef-227c1cc3c2a3" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_BuildingsAndImprovementsGross_20381108-a91a-47f4-ab2b-29381532c1fe" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_BuildingsAndImprovementsGross"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_us-gaap_BuildingsAndImprovementsGross_20381108-a91a-47f4-ab2b-29381532c1fe" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FurnitureAndFixturesGross_d7bcdff0-b9f9-4671-b5a4-08ab1d9b5d64" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FurnitureAndFixturesGross"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_us-gaap_FurnitureAndFixturesGross_d7bcdff0-b9f9-4671-b5a4-08ab1d9b5d64" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_MachineryAndEquipmentGross_1406a6bb-2745-45a1-ba72-9e6ffdea3f44" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_MachineryAndEquipmentGross"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_us-gaap_MachineryAndEquipmentGross_1406a6bb-2745-45a1-ba72-9e6ffdea3f44" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseholdImprovementsGross_d8ad73e9-fc38-4805-9aea-f5138c127472" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LeaseholdImprovementsGross"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_us-gaap_LeaseholdImprovementsGross_d8ad73e9-fc38-4805-9aea-f5138c127472" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_BreedingandProductionAnimalsGross_8e01ade5-c61a-4311-97c7-b38f7c0cddf1" xlink:href="pgen-20231231.xsd#pgen_BreedingandProductionAnimalsGross"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_pgen_BreedingandProductionAnimalsGross_8e01ade5-c61a-4311-97c7-b38f7c0cddf1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_ComputerHardwareandSoftware_d5258572-a647-4a75-8a0f-e9ced433e42b" xlink:href="pgen-20231231.xsd#pgen_ComputerHardwareandSoftware"/>
<link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_pgen_ComputerHardwareandSoftware_d5258572-a647-4a75-8a0f-e9ced433e42b" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionInProgressGross_9ad94187-c1d0-4383-b6d3-450b72c3b7bc" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ConstructionInProgressGross"/>
<link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_7049b4c9-df33-4dad-9d9b-cf846d9cd065" xlink:to="loc_us-gaap_ConstructionInProgressGross_9ad94187-c1d0-4383-b6d3-450b72c3b7bc" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/GoodwillandIntangibleAssetsNetScheduleofIntangibleAssetsDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#GoodwillandIntangibleAssetsNetScheduleofIntangibleAssetsDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/GoodwillandIntangibleAssetsNetScheduleofIntangibleAssetsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_82bd16e4-d5cb-4110-bdb1-7d0a9d314e05" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_0cd9e25f-ccf7-48fd-980a-83542345831e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_82bd16e4-d5cb-4110-bdb1-7d0a9d314e05" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_0cd9e25f-ccf7-48fd-980a-83542345831e" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_6582383b-524a-46c4-b6fa-91b17c54ac95" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_82bd16e4-d5cb-4110-bdb1-7d0a9d314e05" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_6582383b-524a-46c4-b6fa-91b17c54ac95" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/GoodwillandIntangibleAssetsNetScheduleofDefiniteLivedIntangibleAssetsEstimatedFutureAmortizationExpenseDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#GoodwillandIntangibleAssetsNetScheduleofDefiniteLivedIntangibleAssetsEstimatedFutureAmortizationExpenseDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/GoodwillandIntangibleAssetsNetScheduleofDefiniteLivedIntangibleAssetsEstimatedFutureAmortizationExpenseDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_05619cf0-47d1-4dfb-b7b4-26c4a1c26b41" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_12ff1f31-0eab-41d1-836e-4ddeae4ceb34" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_05619cf0-47d1-4dfb-b7b4-26c4a1c26b41" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_12ff1f31-0eab-41d1-836e-4ddeae4ceb34" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_b5de231e-f2fc-4438-a56b-8dc08f37321d" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_05619cf0-47d1-4dfb-b7b4-26c4a1c26b41" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_b5de231e-f2fc-4438-a56b-8dc08f37321d" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_07ba625e-8f51-4ac5-a4b8-9a8b199cd5d1" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_05619cf0-47d1-4dfb-b7b4-26c4a1c26b41" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_07ba625e-8f51-4ac5-a4b8-9a8b199cd5d1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_af60c585-4617-40f3-9fb8-772e801ca533" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_05619cf0-47d1-4dfb-b7b4-26c4a1c26b41" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_af60c585-4617-40f3-9fb8-772e801ca533" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_f72b983a-ae98-411f-a6b8-310956bbedb3" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_05619cf0-47d1-4dfb-b7b4-26c4a1c26b41" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_f72b983a-ae98-411f-a6b8-310956bbedb3" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_ad04e91c-6eba-41ac-b1bd-27a0935051ad" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_05619cf0-47d1-4dfb-b7b4-26c4a1c26b41" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_ad04e91c-6eba-41ac-b1bd-27a0935051ad" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/LinesofCreditandLongTermDebtComponentsofInterestExpenseDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#LinesofCreditandLongTermDebtComponentsofInterestExpenseDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/LinesofCreditandLongTermDebtComponentsofInterestExpenseDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_71d6e789-4ae5-4a88-a028-51eb013ab2cf" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestExpenseDebt"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebtExcludingAmortization_388c3232-5ba0-4c5d-85cf-2bcd6632136e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_InterestExpenseDebtExcludingAmortization"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpenseDebt_71d6e789-4ae5-4a88-a028-51eb013ab2cf" xlink:to="loc_us-gaap_InterestExpenseDebtExcludingAmortization_388c3232-5ba0-4c5d-85cf-2bcd6632136e" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_InterestExpenseDebtAmortizationofDebtDiscountPremiumandDebtIssuanceCosts_0fa6e60f-688d-4f67-b8d3-9171a742b9c3" xlink:href="pgen-20231231.xsd#pgen_InterestExpenseDebtAmortizationofDebtDiscountPremiumandDebtIssuanceCosts"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpenseDebt_71d6e789-4ae5-4a88-a028-51eb013ab2cf" xlink:to="loc_pgen_InterestExpenseDebtAmortizationofDebtDiscountPremiumandDebtIssuanceCosts_0fa6e60f-688d-4f67-b8d3-9171a742b9c3" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/IncomeTaxesComponentsofIncomeTaxBenefitDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#IncomeTaxesComponentsofIncomeTaxBenefitDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/IncomeTaxesComponentsofIncomeTaxBenefitDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_f4014f9a-f2e5-4254-9a74-06420eaa280a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_32e998f6-e114-4b58-b74f-4d5088ea0edf" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredFederalIncomeTaxExpenseBenefit"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_f4014f9a-f2e5-4254-9a74-06420eaa280a" xlink:to="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_32e998f6-e114-4b58-b74f-4d5088ea0edf" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_e0d600ac-29b5-4153-aabe-76aba1a3a136" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_f4014f9a-f2e5-4254-9a74-06420eaa280a" xlink:to="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_e0d600ac-29b5-4153-aabe-76aba1a3a136" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentForeignTaxExpenseBenefit_64b0985c-15b6-4ecb-9d61-5476b32a022f" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CurrentForeignTaxExpenseBenefit"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_f4014f9a-f2e5-4254-9a74-06420eaa280a" xlink:to="loc_us-gaap_CurrentForeignTaxExpenseBenefit_64b0985c-15b6-4ecb-9d61-5476b32a022f" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_52611090-497d-4ede-a20d-ee91010523f7" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredForeignIncomeTaxExpenseBenefit"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_f4014f9a-f2e5-4254-9a74-06420eaa280a" xlink:to="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_52611090-497d-4ede-a20d-ee91010523f7" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_91461251-633c-4645-9ea7-6e263ee64960" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CurrentStateAndLocalTaxExpenseBenefit"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_f4014f9a-f2e5-4254-9a74-06420eaa280a" xlink:to="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_91461251-633c-4645-9ea7-6e263ee64960" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/IncomeTaxesScheduleofEffectiveIncomeTaxRateReconciliationDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#IncomeTaxesScheduleofEffectiveIncomeTaxRateReconciliationDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/IncomeTaxesScheduleofEffectiveIncomeTaxRateReconciliationDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:href="pgen-20231231.xsd#pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_9d99ebbf-7d77-456a-b9f0-414bbabf3326" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_9d99ebbf-7d77-456a-b9f0-414bbabf3326" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_e7138984-6afa-48d3-b49c-2954c4816a52" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_e7138984-6afa-48d3-b49c-2954c4816a52" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_f570b950-bf2a-4787-a523-b0f578025bd6" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_f570b950-bf2a-4787-a523-b0f578025bd6" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensation_514fe3e7-9b3b-438e-813f-7a7f7ace0c45" xlink:href="pgen-20231231.xsd#pgen_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensation"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_pgen_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensation_514fe3e7-9b3b-438e-813f-7a7f7ace0c45" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationTaxCreditsResearch_8fa785c0-e604-4a30-93e6-b1cf39147f99" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationTaxCreditsResearch"/>
<link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_us-gaap_IncomeTaxReconciliationTaxCreditsResearch_8fa785c0-e604-4a30-93e6-b1cf39147f99" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_973560c9-40bf-4598-8e80-5d7d1905f5ab" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_973560c9-40bf-4598-8e80-5d7d1905f5ab" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost_ae89fa08-8b81-4fb8-a818-142c21dc69e6" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost"/>
<link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost_ae89fa08-8b81-4fb8-a818-142c21dc69e6" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseEquityInvestmentLoss_06ef22ed-57e8-4f5c-bf55-4c4740d45805" xlink:href="pgen-20231231.xsd#pgen_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseEquityInvestmentLoss"/>
<link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_pgen_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseEquityInvestmentLoss_06ef22ed-57e8-4f5c-bf55-4c4740d45805" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses_0bce8d32-0f16-4d16-8dac-3843e93fbc62" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses"/>
<link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_3d094f20-cef0-42f2-ad42-3cd6b50b1600" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses_0bce8d32-0f16-4d16-8dac-3843e93fbc62" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_ebd4e685-2486-40cb-b824-dd58ea34127b" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_944f9f0c-2a81-4019-ab6b-940492583a3f" xlink:href="pgen-20231231.xsd#pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_ebd4e685-2486-40cb-b824-dd58ea34127b" xlink:to="loc_pgen_IncomeTaxReconciliationIncomeTaxExpenseBenefitBeforeValuationAllowance_944f9f0c-2a81-4019-ab6b-940492583a3f" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_6824dfeb-3490-468f-ba0d-e7719635c233" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_ebd4e685-2486-40cb-b824-dd58ea34127b" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_6824dfeb-3490-468f-ba0d-e7719635c233" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/IncomeTaxesScheduleofDeferredTaxAssetsandLiabilitiesDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#IncomeTaxesScheduleofDeferredTaxAssetsandLiabilitiesDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/IncomeTaxesScheduleofDeferredTaxAssetsandLiabilitiesDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_5c218b0d-c558-4a48-b22f-102b8ed6d8a7" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsNet"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_c9e687d0-c602-49b5-becb-cc4f6ea9ed58" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGross"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_5c218b0d-c558-4a48-b22f-102b8ed6d8a7" xlink:to="loc_us-gaap_DeferredTaxAssetsGross_c9e687d0-c602-49b5-becb-cc4f6ea9ed58" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_c705799a-2578-4043-b86e-3ba91987c053" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>
<link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_5c218b0d-c558-4a48-b22f-102b8ed6d8a7" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_c705799a-2578-4043-b86e-3ba91987c053" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilities_0c4323f5-b97d-4d68-803d-0bc509616be9" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxLiabilities"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_d9d4a609-0090-4028-8c7e-830934d906cd" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsNet"/>
<link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxLiabilities_0c4323f5-b97d-4d68-803d-0bc509616be9" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_d9d4a609-0090-4028-8c7e-830934d906cd" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_051725db-bcfb-4dc1-9329-de583ddc0aa6" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxLiabilities_0c4323f5-b97d-4d68-803d-0bc509616be9" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_051725db-bcfb-4dc1-9329-de583ddc0aa6" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_1c329bab-1b6e-44ea-ad40-3fc9d6758abc" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_26499ce7-9e1d-4b06-83e9-16ec78802a93" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_1c329bab-1b6e-44ea-ad40-3fc9d6758abc" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_26499ce7-9e1d-4b06-83e9-16ec78802a93" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesLeasingArrangements_27af375a-7bcd-4336-898c-034a3d063283" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxLiabilitiesLeasingArrangements"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_1c329bab-1b6e-44ea-ad40-3fc9d6758abc" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesLeasingArrangements_27af375a-7bcd-4336-898c-034a3d063283" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGross"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_DeferredTaxAssetEquityMethodInvestmentsandInvestmentsAccountedForUnderTheFairValueOption_4c38b5fa-2c08-4f0e-b18e-672b48c7c90d" xlink:href="pgen-20231231.xsd#pgen_DeferredTaxAssetEquityMethodInvestmentsandInvestmentsAccountedForUnderTheFairValueOption"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_pgen_DeferredTaxAssetEquityMethodInvestmentsandInvestmentsAccountedForUnderTheFairValueOption_4c38b5fa-2c08-4f0e-b18e-672b48c7c90d" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_17ebe79f-2a08-4358-9b5a-e96727bfc0d3" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_17ebe79f-2a08-4358-9b5a-e96727bfc0d3" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_a91e6b15-92b3-45b2-9b70-b25836122151" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_a91e6b15-92b3-45b2-9b70-b25836122151" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsDeferredIncome_3affb01f-5739-4b31-b82e-e00d20bed236" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsDeferredIncome"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsDeferredIncome_3affb01f-5739-4b31-b82e-e00d20bed236" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_96c4ebba-b72f-4178-880c-05647442e4c1" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_96c4ebba-b72f-4178-880c-05647442e4c1" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_08e520af-4fe3-4b12-b845-e5de5bf0e5e9" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_08e520af-4fe3-4b12-b845-e5de5bf0e5e9" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_DeferredTaxAssetsOperatingCapitalLossAndInterestExpenseCarryforwards_23b838bc-144f-44af-b8a6-38d0195f517c" xlink:href="pgen-20231231.xsd#pgen_DeferredTaxAssetsOperatingCapitalLossAndInterestExpenseCarryforwards"/>
<link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_pgen_DeferredTaxAssetsOperatingCapitalLossAndInterestExpenseCarryforwards_23b838bc-144f-44af-b8a6-38d0195f517c" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_pgen_DeferredTaxAssetsLeaseLiabilities_6462d7df-7dbd-4180-aa31-930ff672f201" xlink:href="pgen-20231231.xsd#pgen_DeferredTaxAssetsLeaseLiabilities"/>
<link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_pgen_DeferredTaxAssetsLeaseLiabilities_6462d7df-7dbd-4180-aa31-930ff672f201" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment_705e2dff-fc4a-42fc-88eb-0f57dba3d705" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment"/>
<link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment_705e2dff-fc4a-42fc-88eb-0f57dba3d705" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_500b4c74-5b1f-4ec9-88cc-8ab8c1fdfd5e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment"/>
<link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_500b4c74-5b1f-4ec9-88cc-8ab8c1fdfd5e" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities_c2bcfe58-155c-4be7-a182-1142340993a0" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities"/>
<link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_747b83fe-ec49-4df8-b882-bea7dae8cbfc" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities_c2bcfe58-155c-4be7-a182-1142340993a0" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/OperatingLeasesComponentsofLeaseCostsDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#OperatingLeasesComponentsofLeaseCostsDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/OperatingLeasesComponentsofLeaseCostsDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCost_16c72abd-1340-41ab-a8e1-7ded1bf54987" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LeaseCost"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_561a436e-7925-4b4c-86c7-dcc75b731e00" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseCost"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_16c72abd-1340-41ab-a8e1-7ded1bf54987" xlink:to="loc_us-gaap_OperatingLeaseCost_561a436e-7925-4b4c-86c7-dcc75b731e00" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermLeaseCost_31a316d8-d769-4c67-811c-77cbbb461a48" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ShortTermLeaseCost"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_16c72abd-1340-41ab-a8e1-7ded1bf54987" xlink:to="loc_us-gaap_ShortTermLeaseCost_31a316d8-d769-4c67-811c-77cbbb461a48" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableLeaseCost_681aac34-7188-4586-8338-9402fe52ad52" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_VariableLeaseCost"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_16c72abd-1340-41ab-a8e1-7ded1bf54987" xlink:to="loc_us-gaap_VariableLeaseCost_681aac34-7188-4586-8338-9402fe52ad52" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/OperatingLeasesMaturitiesofLeaseLiabilitiesDetails" xlink:type="simple" xlink:href="pgen-20231231.xsd#OperatingLeasesMaturitiesofLeaseLiabilitiesDetails"/>
<link:calculationLink xlink:role="http://www.dna.com/role/OperatingLeasesMaturitiesofLeaseLiabilitiesDetails" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0f2de68d-df26-4dca-808a-f6d220db961f" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_2b580659-fced-4b94-aedd-4c1583ee43ed" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0f2de68d-df26-4dca-808a-f6d220db961f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_2b580659-fced-4b94-aedd-4c1583ee43ed" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_23f6a815-31fd-4623-9aae-012d92d87625" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0f2de68d-df26-4dca-808a-f6d220db961f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_23f6a815-31fd-4623-9aae-012d92d87625" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_b94981dd-1ead-487e-8a23-c1ba3d102f7d" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
<link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0f2de68d-df26-4dca-808a-f6d220db961f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_b94981dd-1ead-487e-8a23-c1ba3d102f7d" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_ab7ed08f-2cb8-4e29-ac8c-b25d7bc5bbdf" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive"/>
<link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0f2de68d-df26-4dca-808a-f6d220db961f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_ab7ed08f-2cb8-4e29-ac8c-b25d7bc5bbdf" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_018e98e5-37d2-4ea4-b21c-00d5dabe6d44" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
<link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0f2de68d-df26-4dca-808a-f6d220db961f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_018e98e5-37d2-4ea4-b21c-00d5dabe6d44" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_14a037e1-8efb-4e0e-a4bd-a51a3009fd99" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
<link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0f2de68d-df26-4dca-808a-f6d220db961f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_14a037e1-8efb-4e0e-a4bd-a51a3009fd99" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_e8751fcc-5d31-42e8-a426-f6d162a993d8" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiability"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_67b58f79-0033-432f-a7e9-54df42cf430f" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_e8751fcc-5d31-42e8-a426-f6d162a993d8" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_67b58f79-0033-432f-a7e9-54df42cf430f" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_278491b4-f4bc-417e-90dd-577911b29d3a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_e8751fcc-5d31-42e8-a426-f6d162a993d8" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_278491b4-f4bc-417e-90dd-577911b29d3a" xlink:type="arc"/>
</link:calculationLink>
<link:roleRef roleURI="http://www.dna.com/role/OperatingLeasesMaturitiesofLeaseLiabilitiesDetails_1" xlink:type="simple" xlink:href="pgen-20231231.xsd#OperatingLeasesMaturitiesofLeaseLiabilitiesDetails_1"/>
<link:calculationLink xlink:role="http://www.dna.com/role/OperatingLeasesMaturitiesofLeaseLiabilitiesDetails_1" xlink:type="extended">
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_2f147ae3-4329-46fc-9542-4899ea95960a" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_460a5fbd-23d1-4b71-9dd2-268fe2eca53e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
<link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_2f147ae3-4329-46fc-9542-4899ea95960a" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_460a5fbd-23d1-4b71-9dd2-268fe2eca53e" xlink:type="arc"/>
<link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_d48de159-ed2f-4dea-913a-24a94d9c422d" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_OperatingLeaseLiability"/>
<link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_2f147ae3-4329-46fc-9542-4899ea95960a" xlink:to="loc_us-gaap_OperatingLeaseLiability_d48de159-ed2f-4dea-913a-24a94d9c422d" xlink:type="arc"/>
</link:calculationLink>
</link:linkbase>


21 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 8/09/23  Precigen, Inc.                    10-Q        6/30/23   93:17M
 7/06/23  Precigen, Inc.                    S-8         7/06/23    5:212K                                   Davis Polk & … LLP 01/FA
11/09/20  Precigen, Inc.                    10-Q        9/30/20  117:12M
 6/22/20  Precigen, Inc.                    S-3                    7:747K                                   Donnelley … Solutions/FA
 6/19/20  Precigen, Inc.                    8-K:5,9     6/19/20   11:175K                                   Donnelley … Solutions/FA
 6/04/20  Precigen, Inc.                    8-K:5,9     6/03/20   11:295K                                   Donnelley … Solutions/FA
 5/11/20  Precigen, Inc.                    10-Q        3/31/20  111:10M
 3/02/20  Precigen, Inc.                    10-K       12/31/19  141:33M                                    Workiva Inc Wde… FA01/FA
 2/04/20  Precigen, Inc.                    8-K:2,5,8,9 1/30/20   13:379K                                   Donnelley … Solutions/FA
 1/07/20  Precigen, Inc.                    8-K:5,9     1/01/20   11:240K                                   Donnelley … Solutions/FA
 8/09/19  Precigen, Inc.                    10-Q        6/30/19  116:12M
 6/12/19  Precigen, Inc.                    8-K:5,9     6/12/19    2:43K                                    Donnelley … Solutions/FA
 5/09/19  Precigen, Inc.                    10-Q        3/31/19  109:8.9M
 6/08/18  Precigen, Inc.                    8-K:5,9     6/07/18    2:36K                                    Donnelley … Solutions/FA
 3/01/18  Precigen, Inc.                    10-K       12/31/17  138:16M
 6/30/17  Precigen, Inc.                    8-K:5,9     6/28/17    2:35K                                    Donnelley … Solutions/FA
 6/13/16  Precigen, Inc.                    8-K:5,9     6/09/16    2:29K                                    Donnelley … Solutions/FA
 6/17/15  Precigen, Inc.                    8-K:5,9     6/11/15    3:101K                                   Donnelley … Solutions/FA
 1/14/15  Precigen, Inc.                    8-K:1,3,9   1/09/15    6:489K                                   Donnelley … Solutions/FA
 6/13/14  Precigen, Inc.                    8-K:5,9     6/09/14    5:407K                                   Donnelley … Solutions/FA
 7/29/13  Precigen, Inc.                    S-1/A                 15:5.3M                                   Donnelley … Solutions/FA
Top
Filing Submission 0001356090-24-000007   –   Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)

Copyright © 2024 Fran Finnegan & Company LLC – All Rights Reserved.
AboutPrivacyRedactionsHelp — Tue., May 14, 6:08:59.1am ET