SEC Info - Silo Pharma, Inc. - ‘10-K’ for 12/31/23

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Silo Pharma, Inc. – ‘10-K’ for 12/31/23 – ‘EX-101.SCH’

On: Monday, 3/25/24, at 5:23pm ET · For: 12/31/23 · Accession #: 1213900-24-25615 · File #: 1-41512

Previous ‘10-K’: ‘10-K’ on 3/24/23 for 12/31/22 · Latest ‘10-K’: This Filing · 16 References:

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 3/25/24  Silo Pharma, Inc.                 10-K       12/31/23   69:6.7M                                   EdgarAgents LLC/FA

Annual Report — Form 10-K — SEA’34

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   1.37M 
 2: EX-4.1      Description of the Registrant's Securities          HTML     33K 
 3: EX-21.1     Subsidiaries List                                   HTML     20K 
 4: EX-23.1     Consent on Independent Registered Accounting Firm   HTML     20K 
 8: EX-97.1     Silo Pharma, Inc. Clawback Policy                   HTML     61K 
 5: EX-31.1     Certification -- §302 - SOA'02                      HTML     25K 
 6: EX-31.2     Certification -- §302 - SOA'02                      HTML     25K 
 7: EX-32.1     Certification -- §906 - SOA'02                      HTML     22K 
14: R1          Cover                                               HTML     94K 
15: R2          Audit Information                                   HTML     26K 
16: R3          Consolidated Balance Sheets                         HTML    115K 
17: R4          Consolidated Balance Sheets (Parentheticals)        HTML     41K 
18: R5          Consolidated Statements of Operations and           HTML    143K 
                Comprehensive Loss                                               
19: R6          Consolidated Statements of Operations and           HTML     32K 
                Comprehensive Loss (Parentheticals)                              
20: R7          Consolidated Statements of Changes in               HTML     75K 
                Stockholders? Equity                                             
21: R8          Consolidated Statements of Cash Flows               HTML    100K 
22: R9          Organization and Business                           HTML     29K 
23: R10         Summary of Significant Accounting Policies          HTML     48K 
24: R11         Fair Value of Financial Instruments and Fair Value  HTML     45K 
                Measurements                                                     
25: R12         Disposal of the Discontinued Operations of the      HTML     30K 
                NFID Business                                                    
26: R13         Note Receivable                                     HTML     28K 
27: R14         Stockholders? Equity                                HTML     52K 
28: R15         Concentrations                                      HTML     24K 
29: R16         Commitments and Contingencies                       HTML     85K 
30: R17         Income Taxes                                        HTML     34K 
31: R18         Subsequent Events                                   HTML     24K 
32: R19         Pay vs Performance Disclosure                       HTML     33K 
33: R20         Insider Trading Arrangements                        HTML     27K 
34: R21         Accounting Policies, by Policy (Policies)           HTML     82K 
35: R22         Summary of Significant Accounting Policies          HTML     26K 
                (Tables)                                                         
36: R23         Fair Value of Financial Instruments and Fair Value  HTML     37K 
                Measurements (Tables)                                            
37: R24         Disposal of the Discontinued Operations of the      HTML     30K 
                NFID Business (Tables)                                           
38: R25         Note Receivable (Tables)                            HTML     26K 
39: R26         Stockholders? Equity (Tables)                       HTML     40K 
40: R27         Commitments and Contingencies (Tables)              HTML     35K 
41: R28         Income Taxes (Tables)                               HTML     32K 
42: R29         Organization and Business (Details)                 HTML     33K 
43: R30         Summary of Significant Accounting Policies          HTML     65K 
                (Details)                                                        
44: R31         Summary of Significant Accounting Policies          HTML     28K 
                (Details) - Schedule of Potentially Dilutive                     
                Shares                                                           
45: R32         Fair Value of Financial Instruments and Fair Value  HTML     44K 
                Measurements (Details)                                           
46: R33         Fair Value of Financial Instruments and Fair Value  HTML     35K 
                Measurements (Details) - Schedule of Financial                   
                Assets and Liabilities Measured at Fair Value on a               
                Recurring Basis                                                  
47: R34         Fair Value of Financial Instruments and Fair Value  HTML     41K 
                Measurements (Details) - Schedule of Summarizes                  
                Activity in the Company?s Short Term Investments                 
                and Equity Investments at Fair Value                             
48: R35         Disposal of the Discontinued Operations of the      HTML     47K 
                NFID Business (Details)                                          
49: R36         Disposal of the Discontinued Operations of the      HTML     33K 
                NFID Business (Details) - Schedule of Operating                  
                Result of Discontinued Operations of the NFID                    
                Business                                                         
50: R37         Note Receivable (Details)                           HTML     40K 
51: R38         Note Receivable (Details) - Schedule of Note        HTML     36K 
                Receivable                                                       
52: R39         Stockholders? Equity (Details)                      HTML    210K 
53: R40         Stockholders? Equity (Details) - Schedule of Stock  HTML     53K 
                Option Activities                                                
54: R41         Stockholders? Equity (Details) - Schedule of        HTML     59K 
                Warrant Activities                                               
55: R42         Concentrations (Details)                            HTML     31K 
56: R43         Commitments and Contingencies (Details)             HTML    437K 
57: R44         Commitments and Contingencies (Details) - Schedule  HTML     34K 
                of Milestone Payments                                            
58: R45         Commitments and Contingencies (Details) - Schedule  HTML     43K 
                of Minimum Annual Royalty Payments                               
59: R46         Commitments and Contingencies (Details) - Schedule  HTML     30K 
                of Shall Pay UMB Fees                                            
60: R47         Commitments and Contingencies (Details) - Schedule  HTML     25K 
                of Future Amounts Due Under Sponsored Study and                  
                Research Agreements                                              
61: R48         Income Taxes (Details)                              HTML     29K 
62: R49         Income Taxes (Details) - Schedule of Income Taxes   HTML     34K 
                at the Effective Statutory Rate and the Provision                
                for Income Taxes                                                 
63: R50         Income Taxes (Details) - Schedule of Net Deferred   HTML     29K 
                Tax Asset                                                        
64: R51         Subsequent Events (Details)                         HTML     34K 
66: XML         IDEA XML File -- Filing Summary                      XML    122K 
69: XML         XBRL Instance -- ea0201957-10k_silopharma_htm        XML    974K 
65: EXCEL       IDEA Workbook of Financial Report Info              XLSX    151K 
10: EX-101.CAL  XBRL Calculations -- silo-20231231_cal               XML    105K 
11: EX-101.DEF  XBRL Definitions -- silo-20231231_def                XML    783K 
12: EX-101.LAB  XBRL Labels -- silo-20231231_lab                     XML   1.45M 
13: EX-101.PRE  XBRL Presentations -- silo-20231231_pre              XML    728K 
 9: EX-101.SCH  XBRL Schema -- silo-20231231                         XSD    196K 
67: JSON        XBRL Instance as JSON Data -- MetaLinks              508±   728K 
68: ZIP         XBRL Zipped Folder -- 0001213900-24-025615-xbrl      Zip    541K

‘EX-101.SCH’ — XBRL Schema — silo-20231231

This Exhibit is an XBRL File.

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<link:definition> 995311 - Disclosure - Note Receivable </link:definition>

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<link:definition> 995312 - Disclosure - Stockholders’ Equity </link:definition>

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<link:definition> 995313 - Disclosure - Concentrations </link:definition>

<link:usedOn> link:presentationLink </link:usedOn>

<link:usedOn> link:definitionLink </link:usedOn>

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<link:definition> 995314 - Disclosure - Commitments and Contingencies </link:definition>

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<link:definition> 995315 - Disclosure - Income Taxes </link:definition>

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<link:definition> 995316 - Disclosure - Subsequent Events </link:definition>

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<link:definition> 996002 - Disclosure - Fair Value of Financial Instruments and Fair Value Measurements (Tables) </link:definition>

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<link:usedOn> link:presentationLink </link:usedOn>

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<link:roleType roleURI="http://www.silopharma.com/role/NoteReceivableTables" id="silo_r_NoteReceivableTables">

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<link:definition> 996018 - Disclosure - Stockholders’ Equity (Details) </link:definition>

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<link:definition> 996019 - Disclosure - Stockholders’ Equity (Details) - Schedule of Stock Option Activities </link:definition>

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<link:definition> 996020 - Disclosure - Stockholders’ Equity (Details) - Schedule of Warrant Activities </link:definition>

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<xs:element name="CommitmentsandContingenciesDetailsScheduleofMilestonePaymentsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_CommitmentsandContingenciesDetailsScheduleofMilestonePaymentsTable"/>

<xs:element name="CommitmentsandContingenciesDetailsScheduleofMilestonePaymentsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_CommitmentsandContingenciesDetailsScheduleofMilestonePaymentsLineItems"/>

<xs:element name="MilestoneBalanceDescription" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_MilestoneBalanceDescription"/>

<xs:element name="MilestonePayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="silo_MilestonePayment"/>

<xs:element name="CommitmentsandContingenciesDetailsScheduleofMinimumAnnualRoyaltyPaymentsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_CommitmentsandContingenciesDetailsScheduleofMinimumAnnualRoyaltyPaymentsTable"/>

<xs:element name="MinimumAnnualRoyaltyPaymentsDescription" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_MinimumAnnualRoyaltyPaymentsDescription"/>

<xs:element name="CommitmentsandContingenciesDetailsScheduleofShallPayUMBFeesTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_CommitmentsandContingenciesDetailsScheduleofShallPayUMBFeesTable"/>

<xs:element name="CommitmentsandContingenciesDetailsScheduleofShallPayUMBFeesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_CommitmentsandContingenciesDetailsScheduleofShallPayUMBFeesLineItems"/>

<xs:element name="PaymentDescription" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_PaymentDescription"/>

<xs:element name="OrganizationandBusinessDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_OrganizationandBusinessDetailsTable"/>

<xs:element name="OrganizationandBusinessDetailsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_OrganizationandBusinessDetailsLineItems"/>

<xs:element name="SummaryofSignificantAccountingPoliciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_SummaryofSignificantAccountingPoliciesDetailsTable"/>

<xs:element name="WorkingCapital" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_WorkingCapital"/>

<xs:element name="CashSPICInsuredAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="silo_CashSPICInsuredAmount"/>

<xs:element name="BadDebtExpense" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_BadDebtExpense"/>

<xs:element name="FairValueofFinancialInstrumentsandFairValueMeasurementsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_FairValueofFinancialInstrumentsandFairValueMeasurementsDetailsTable"/>

<xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="silo_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodValue"/>

<xs:element name="DisposaloftheDiscontinuedOperationsoftheNFIDBusinessDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_DisposaloftheDiscontinuedOperationsoftheNFIDBusinessDetailsTable"/>

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<xs:element name="StockholdersEquityDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_StockholdersEquityDetailsTable"/>

<xs:element name="PreferredStockShareDesignated" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="silo_PreferredStockShareDesignated"/>

<xs:element name="RestrictedCommonSharePrice" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_RestrictedCommonSharePrice"/>

<xs:element name="CommonStockPurchaseCost" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_CommonStockPurchaseCost"/>

<xs:element name="AggregateOfIncentiveStockOptions" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_AggregateOfIncentiveStockOptions"/>

<xs:element name="StockOptionValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_StockOptionValue"/>

<xs:element name="ConcentrationsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_ConcentrationsDetailsTable"/>

<xs:element name="CommitmentsandContingenciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_CommitmentsandContingenciesDetailsTable"/>

<xs:element name="ExtensionFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_ExtensionFee"/>

<xs:element name="CommercialSaleTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_CommercialSaleTerm"/>

<xs:element name="LicenseAgreementExpire" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_LicenseAgreementExpire"/>

<xs:element name="SublicenseIncomeReceivablePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SublicenseIncomeReceivablePercentage"/>

<xs:element name="DueToRelatedPartieCurrent" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_DueToRelatedPartieCurrent"/>

<xs:element name="SalesOfLicensedProductsPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SalesOfLicensedProductsPercentage"/>

<xs:element name="SublicenseIncomePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SublicenseIncomePercentage"/>

<xs:element name="SublicenseAgreementAmountPaid" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="silo_SublicenseAgreementAmountPaid"/>

<xs:element name="NonrefundableCashPayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="silo_NonrefundableCashPayment"/>

<xs:element name="NetSalePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_NetSalePercentage"/>

<xs:element name="LicensorShare" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_LicensorShare"/>

<xs:element name="AggregateOfConvertedShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_AggregateOfConvertedShares"/>

<xs:element name="RevenueTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_RevenueTerm"/>

<xs:element name="TradingPrice" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_TradingPrice"/>

<xs:element name="SecuritiesReceived" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="silo_SecuritiesReceived"/>

<xs:element name="ConsiderationFeePayablePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ConsiderationFeePayablePercentage"/>

<xs:element name="UpfrontLicenseFees" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_UpfrontLicenseFees"/>

<xs:element name="FirstCommercialSale" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_FirstCommercialSale"/>

<xs:element name="AgreementShallExpire" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_AgreementShallExpire"/>

<xs:element name="SponsoredStudyAgreement" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="silo_SponsoredStudyAgreement"/>

<xs:element name="SponsoredResearchAgreementDescription" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SponsoredResearchAgreementDescription"/>

<xs:element name="ResearchProjectEstimatePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ResearchProjectEstimatePercentage"/>

<xs:element name="JointVentureInterestRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_JointVentureInterestRate"/>

<xs:element name="SubsequentEventsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="silo_SubsequentEventsDetailsTable"/>

<xs:element name="AikidoPharmaIncMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_AikidoPharmaIncMember"/>

<xs:element name="AmendedServiceAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_AmendedServiceAgreementMember"/>

<xs:element name="AmendmentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_AmendmentMember"/>

<xs:element name="AmplifyBioResearchAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_AmplifyBioResearchAgreementMember"/>

<xs:element name="ConversionOfSeriesCConvertiblePreferredStockIntoCommonStockMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ConversionOfSeriesCConvertiblePreferredStockIntoCommonStockMember"/>

<xs:element name="CustomerConcentrationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_CustomerConcentrationMember"/>

<xs:element name="CustomerPatentLicenseAgreementWithAikidoPharmaIncMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_CustomerPatentLicenseAgreementWithAikidoPharmaIncMember"/>

<xs:element name="CustomerSublicenseAgreementWithAikidoPharmaIncMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_CustomerSublicenseAgreementWithAikidoPharmaIncMember"/>

<xs:element name="DanielRyweckMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_DanielRyweckMember"/>

<xs:element name="DrJamesKuoMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_DrJamesKuoMember"/>

<xs:element name="EricWeisblumMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_EricWeisblumMember"/>

<xs:element name="ExtensionFeeMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ExtensionFeeMember"/>

<xs:element name="FirstPaymentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_FirstPaymentMember"/>

<xs:element name="HomeBistroIncMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_HomeBistroIncMember"/>

<xs:element name="IncentiveStockOptionMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_IncentiveStockOptionMember"/>

<xs:element name="InvestigatorSponsoredStudyAgreementWithUniversityOfMarylandBaltimoreMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_InvestigatorSponsoredStudyAgreementWithUniversityOfMarylandBaltimoreMember"/>

<xs:element name="JVAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_JVAgreementMember"/>

<xs:element name="MasterLincenseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_MasterLincenseAgreementMember"/>

<xs:element name="MrWeisblumMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_MrWeisblumMember"/>

<xs:element name="NoteReceivableMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_NoteReceivableMember"/>

<xs:element name="OmnibusEquityIncentivePlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_OmnibusEquityIncentivePlanMember"/>

<xs:element name="PaymentFiveMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_PaymentFiveMember"/>

<xs:element name="PaymentFourMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_PaymentFourMember"/>

<xs:element name="PaymentOneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_PaymentOneMember"/>

<xs:element name="PaymentThreeMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_PaymentThreeMember"/>

<xs:element name="PaymentTwoMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_PaymentTwoMember"/>

<xs:element name="PromissoryNoteMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_PromissoryNoteMember"/>

<xs:element name="ResearchAgreementWithAmplifyBioMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ResearchAgreementWithAmplifyBioMember"/>

<xs:element name="ResearchAgreementWithReprocellMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ResearchAgreementWithReprocellMember"/>

<xs:element name="ResearchAgreementsWithUppertonPharmaSolutionsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ResearchAgreementsWithUppertonPharmaSolutionsMember"/>

<xs:element name="SecondPaymentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SecondPaymentMember"/>

<xs:element name="SeriesCConversionPriceMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SeriesCConversionPriceMember"/>

<xs:element name="SeriesCConvertiblePreferredStockMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SeriesCConvertiblePreferredStockMember"/>

<xs:element name="SeriesMConvertiblePreferredMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SeriesMConvertiblePreferredMember"/>

<xs:element name="SponsoredResearchAgreementWithColumbiaUniversityMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SponsoredResearchAgreementWithColumbiaUniversityMember"/>

<xs:element name="SponsoredResearchAgreementWithTheRegentsOfTheUniversityOfCaliforniaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SponsoredResearchAgreementWithTheRegentsOfTheUniversityOfCaliforniaMember"/>

<xs:element name="SponsoredResearchAgreementWithUniversityOfMarylandBaltimoreMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SponsoredResearchAgreementWithUniversityOfMarylandBaltimoreMember"/>

<xs:element name="StockOptionsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_StockOptionsMember"/>

<xs:element name="SublicenseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_SublicenseAgreementMember"/>

<xs:element name="ThirdAmendmentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ThirdAmendmentMember"/>

<xs:element name="UniversityOfMarylandBaltimoreMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_UniversityOfMarylandBaltimoreMember"/>

<xs:element name="UppertonResearchAgreementsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_UppertonResearchAgreementsMember"/>

<xs:element name="VendorMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_VendorMember"/>

<xs:element name="ZylTherapeuticsIncMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_ZylTherapeuticsIncMember"/>

<xs:element name="DocumentAndEntityInformationAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="silo_DocumentAndEntityInformationAbstract"/>

</xs:schema>

16 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

12/20/23  Silo Pharma, Inc.                 8-K12B:3,5,12/19/23    7:4.3M                                   EdgarAgents LLC/FA
10/23/23  Silo Pharma, Inc.                 DEF 14A    12/04/23    1:1.7M                                   EdgarAgents LLC 2/FA
10/18/22  Silo Pharma, Inc.                 8-K:1,5,7,810/12/22   15:3.8M                                   EdgarAgents LLC/FA
 9/30/22  Silo Pharma, Inc.                 8-K:1,5,8,9 9/26/22   15:936K                                   EdgarAgents LLC/FA
 2/16/21  Silo Pharma, Inc.                 8-K:1,9     2/12/21    3:500K                                   EdgarAgents LLC/FA
 2/12/21  Silo Pharma, Inc.                 8-K/A:1,3,5 2/09/21    2:136K                                   EdgarAgents LLC/FA
 2/10/21  Silo Pharma, Inc.                 8-K:1,3,5,8 2/09/21    7:679K                                   EdgarAgents LLC/FA
 1/28/21  Silo Pharma, Inc.                 8-K:5,9     1/18/21    3:158K                                   EdgarAgents LLC/FA
 1/11/21  Silo Pharma, Inc.                 8-K:1,9     1/05/20    2:154K                                   EdgarAgents LLC/FA
 1/11/21  Silo Pharma, Inc.                 8-K:1,8,9   1/05/21    4:169K                                   EdgarAgents LLC/FA
 4/29/20  Silo Pharma, Inc.                 8-K:1,3,9   4/28/20    4:437K                                   EdgarAgents LLC/FA
 4/22/20  Silo Pharma, Inc.                 8-K/A:1,3,5 4/15/20    7:359K                                   EdgarAgents LLC/FA
 3/20/20  Silo Pharma, Inc.                 10-K       12/31/19   73:18M                                    EdgarAgents LLC/FA
11/13/19  Silo Pharma, Inc.                 10-Q        9/30/19   54:3.1M                                   EdgarAgents LLC/FA
12/20/18  Silo Pharma, Inc.                 8-K:1,2,9  12/13/18    3:146K                                   EdgarAgents LLC/FA
 4/30/13  Silo Pharma, Inc.                 8-K:1,3,5,9 4/24/13    3:415K                                   M2 Compliance LLC/FA

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Filing Submission 0001213900-24-025615 – Alternative Formats (Word / Rich Text, HTML, Plain Text, et al.)

Silo Pharma, Inc. – ‘10-K’ for 12/31/23 – ‘EX-101.SCH’

On: Monday, 3/25/24, at 5:23pm ET · For: 12/31/23 · Accession #: 1213900-24-25615 · File #: 1-41512

Annual Report — Form 10-K — SEA’34Filing Table of Contents

‘EX-101.SCH’ — XBRL Schema — silo-20231231

This Exhibit is an XBRL File.

16 Previous Filings that this Filing References

Annual Report — Form 10-K — SEA’34

Filing Table of Contents