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As Of Filer Filing For·On·As Docs:Size Issuer Filing Agent 1/12/15 Larimar Therapeutics, Inc. S-1 1/09/15 77:7.7M Donnelley … Solutions/FA |
Document/Exhibit Description Pages Size
1: S-1 Registration Statement (General Form) HTML 1.53M
2: EX-10.3(B) Material Contract HTML 26K
3: EX-10.4 Material Contract HTML 48K
5: EX-23.1 Consent of Experts or Counsel HTML 21K
4: EX-16.1 Letter re: Change in Certifying Accountant HTML 21K
53: R1 Document and Entity Information HTML 36K
42: R2 Consolidated Balance Sheets HTML 108K
51: R3 Consolidated Balance Sheets (Parenthetical) HTML 70K
55: R4 Consolidated Statements of Operations and HTML 77K
Comprehensive Loss
71: R5 Consolidated Statements of Redeemable Convertible HTML 119K
Preferred Stock and Stockholders' Deficit
44: R6 Consolidated Statements of Redeemable Convertible HTML 39K
Preferred Stock and Stockholders' Deficit
(Parenthetical)
50: R7 Consolidated Statements of Cash Flows HTML 139K
38: R8 Nature of the Business and Basis of Presentation HTML 41K
28: R9 Summary of Significant Accounting Policies HTML 98K
72: R10 Property and Equipment, net HTML 32K
57: R11 Accrued Expenses HTML 36K
56: R12 Convertible Promissory Notes HTML 38K
62: R13 Redeemable Convertible Preferred Stock HTML 57K
63: R14 Common Stock HTML 38K
60: R15 Stock-Based Awards HTML 85K
64: R16 Net Loss Per Share HTML 42K
52: R17 Commitments and Contingencies HTML 47K
54: R18 Income Taxes HTML 59K
59: R19 Retirement Plan HTML 29K
77: R20 Australia Research and Development Tax Incentive HTML 32K
67: R21 Related Party Transactions HTML 28K
47: R22 Subsequent Events HTML 27K
58: R23 Summary of Significant Accounting Policies HTML 137K
(Policies)
49: R24 Property and Equipment, net (Tables) HTML 31K
21: R25 Accrued Expenses (Tables) HTML 35K
68: R26 Redeemable Convertible Preferred Stock (Tables) HTML 43K
74: R27 Stock-Based Awards (Tables) HTML 74K
33: R28 Net Loss Per Share (Tables) HTML 46K
32: R29 Commitments and Contingencies (Tables) HTML 38K
36: R30 Income Taxes (Tables) HTML 56K
37: R31 Convertible Promissory Notes (Tables) HTML 28K
39: R32 Nature of the Business and Basis of Presentation - HTML 46K
Additional Information (Detail)
18: R33 Summary of Significant Accounting Policies - HTML 42K
Additional Information (Detail)
65: R34 Schedule of Property and Equipment, Net (Detail) HTML 40K
46: R35 Property and Equipment, net - Additional HTML 26K
Information (Detail)
48: R36 Accrued Expenses - Schedule of Accrued Expenses HTML 45K
(Detail)
24: R37 Convertible Promissory Notes - Additional HTML 63K
Information (Detail)
76: R38 Redeemable Convertible Preferred Stock - HTML 135K
Additional Information (Detail)
12: R39 Schedule of Redeemable Preferred Stock (Detail) HTML 101K
40: R40 Common Stock - Additional Information (Detail) HTML 44K
70: R41 Stock-Based Awards - Additional Information HTML 125K
(Detail)
23: R42 Assumptions used to Determine Fair Value of Stock HTML 36K
Options Granted (Detail)
31: R43 Summary of Stock Options Activity (Detail) HTML 91K
35: R44 Summary of Restricted Stock Activity (Detail) HTML 58K
43: R45 Stock-Based Awards - Summary of Stock-Based HTML 38K
Compensation Expense Related to Stock Options and
Restricted Common Stock (Detail)
17: R46 Computation of Basic and Diluted Earnings Per HTML 45K
Share (Detail)
27: R47 Summary of Common Stock Equivalents Outstanding HTML 39K
(Detail)
14: R48 Commitments and Contingencies - Additional HTML 64K
Information (Detail)
69: R49 Commitments and Contingencies - Schedule of Future HTML 41K
Minimum Lease Payments for Operating Leases
(Detail)
22: R50 Research and Development Expenses Related to HTML 26K
License Agreements (Detail)
66: R51 Income Taxes - Additional Information (Detail) HTML 53K
25: R52 Reconciliation of Federal Statutory Income Tax HTML 59K
Rate (Detail)
41: R53 Schedule of Net Deferred tax Assets (Detail) HTML 69K
13: R54 Summary of Changes in the Valuation Allowance for HTML 32K
Deferred Tax Assets (Detail)
16: R55 Retirement Plan - Additional Information (Detail) HTML 29K
34: R56 Australia Research and Development Tax Incentive - HTML 47K
Additional Information (Detail)
20: R57 Related Party Transactions - Additional HTML 29K
Information (Detail)
73: R58 Subsequent Events - Additional Information HTML 56K
(Detail)
45: R59 Summary of Significant Accounting Policies - HTML 38K
Summary of Common Stock Equivalents Outstanding
(Detail)
61: R60 Notes Payable - Additional Information (Detail) HTML 92K
26: R61 Notes Payable - Schedule of Estimated Future HTML 39K
Principal Payments Due under Term Loan (Detail)
29: R62 Stockholders' Equity - Additional Information HTML 66K
(Detail)
75: XML IDEA XML File -- Filing Summary XML 116K
15: EXCEL IDEA Workbook of Financial Reports XLSX 176K
30: EXCEL IDEA Workbook of Financial Reports (.xls) XLS 826K
6: EX-101.INS XBRL Instance -- zfgn-20140930 XML 1.24M
8: EX-101.CAL XBRL Calculations -- zfgn-20140930_cal XML 182K
9: EX-101.DEF XBRL Definitions -- zfgn-20140930_def XML 489K
10: EX-101.LAB XBRL Labels -- zfgn-20140930_lab XML 1.14M
11: EX-101.PRE XBRL Presentations -- zfgn-20140930_pre XML 838K
7: EX-101.SCH XBRL Schema -- zfgn-20140930 XSD 153K
19: ZIP XBRL Zipped Folder -- 0001193125-15-006755-xbrl Zip 165K
| <?xml version="1.0" standalone="yes" encoding="windows-1252"?> | |||||||||||||||||||||
| <!-- RR Donnelley Xcelerate Instance Document, based on XBRL 2.1 http://www.rrdonnelley.com/ --> | |||||||||||||||||||||
| <!-- Version: 6.22.4 --> | |||||||||||||||||||||
| <!-- Round: 3 --> | |||||||||||||||||||||
| <!-- Creation date: 2015-01-09T18:15:28Z --> | |||||||||||||||||||||
| <!-- Copyright (c) 2005-2013 R.R. Donnelley & Sons Company All Rights Reserved. --> | |||||||||||||||||||||
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| <us-gaap:OperatingLeasesFutureMinimumPaymentsDueInFourYears contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_90CCD92E-3E4A-4B1A-A2AD-43C206CBBFF6_1_4" unitRef="iso4217_USD"> 139000 </us-gaap:OperatingLeasesFutureMinimumPaymentsDueInFourYears> | |||||||||||||||||||||
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| <us-gaap:AccruedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_12" unitRef="iso4217_USD"> 9885000 </us-gaap:AccruedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_37" unitRef="iso4217_USD"> 111196000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:OtherAccruedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_E4DC98C8-B657-4015-AACA-C2DC2311A32A_1_5" unitRef="iso4217_USD"> 92000 </us-gaap:OtherAccruedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesFutureMinimumPaymentsDue contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_90CCD92E-3E4A-4B1A-A2AD-43C206CBBFF6_1_5" unitRef="iso4217_USD"> 660000 </us-gaap:OperatingLeasesFutureMinimumPaymentsDue> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesFutureMinimumPaymentsDueInThreeYears contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_90CCD92E-3E4A-4B1A-A2AD-43C206CBBFF6_1_3" unitRef="iso4217_USD"> 235000 </us-gaap:OperatingLeasesFutureMinimumPaymentsDueInThreeYears> | |||||||||||||||||||||
| <us-gaap:LiabilitiesAndStockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_38" unitRef="iso4217_USD"> 129636000 </us-gaap:LiabilitiesAndStockholdersEquity> | |||||||||||||||||||||
| <us-gaap:AccruedProfessionalFeesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_E4DC98C8-B657-4015-AACA-C2DC2311A32A_1_3" unitRef="iso4217_USD"> 542000 </us-gaap:AccruedProfessionalFeesCurrent> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesFutureMinimumPaymentsDueInTwoYears contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_90CCD92E-3E4A-4B1A-A2AD-43C206CBBFF6_1_2" unitRef="iso4217_USD"> 229000 </us-gaap:OperatingLeasesFutureMinimumPaymentsDueInTwoYears> | |||||||||||||||||||||
| <us-gaap:NotesPayableCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_13" unitRef="iso4217_USD"> 684000 </us-gaap:NotesPayableCurrent> | |||||||||||||||||||||
| <us-gaap:Liabilities contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_16" unitRef="iso4217_USD"> 18440000 </us-gaap:Liabilities> | |||||||||||||||||||||
| <us-gaap:EmployeeRelatedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_E4DC98C8-B657-4015-AACA-C2DC2311A32A_1_2" unitRef="iso4217_USD"> 741000 </us-gaap:EmployeeRelatedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsAtCarryingValue contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_2" unitRef="iso4217_USD"> 127030000 </us-gaap:CashAndCashEquivalentsAtCarryingValue> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentNet contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_6" unitRef="iso4217_USD"> 69000 </us-gaap:PropertyPlantAndEquipmentNet> | |||||||||||||||||||||
| <us-gaap:PrepaidExpenseAndOtherAssetsCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_3" unitRef="iso4217_USD"> 1221000 </us-gaap:PrepaidExpenseAndOtherAssetsCurrent> | |||||||||||||||||||||
| <us-gaap:DeferredOfferingCosts contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="INF" id="id_6893637_199E8A76-9716-466E-B426-5FF1CA2CBF20_1_0" unitRef="iso4217_USD"> 0 </us-gaap:DeferredOfferingCosts> | |||||||||||||||||||||
| <us-gaap:Assets contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_8" unitRef="iso4217_USD"> 129636000 </us-gaap:Assets> | |||||||||||||||||||||
| <us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_5AFB43F0-9D21-4B36-BE3D-A6B3CD7478BF_1001_0" unitRef="iso4217_USD"> 6224000 </us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized> | |||||||||||||||||||||
| <us-gaap:IncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_4" unitRef="iso4217_USD"> 1218000 </us-gaap:IncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:OtherAssetsNoncurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_7" unitRef="iso4217_USD"> 98000 </us-gaap:OtherAssetsNoncurrent> | |||||||||||||||||||||
| <us-gaap:AssetsCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_1_5" unitRef="iso4217_USD"> 129469000 </us-gaap:AssetsCurrent> | |||||||||||||||||||||
| <zfgn:AccruedInterestExpense contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_E4DC98C8-B657-4015-AACA-C2DC2311A32A_1_4" unitRef="iso4217_USD"> 51000 </zfgn:AccruedInterestExpense> | |||||||||||||||||||||
| <zfgn:AccruedResearchAndDevelopmentExpenseCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_E4DC98C8-B657-4015-AACA-C2DC2311A32A_1_1" unitRef="iso4217_USD"> 1759000 </zfgn:AccruedResearchAndDevelopmentExpenseCurrent> | |||||||||||||||||||||
| <zfgn:AccruedLicensingMilestones contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0" decimals="-3" id="id_6893637_E4DC98C8-B657-4015-AACA-C2DC2311A32A_1_0" unitRef="iso4217_USD"> 6700000 </zfgn:AccruedLicensingMilestones> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsFairValueDisclosure contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1269038x1272304" decimals="-3" id="id_6893637_0A9DE055-8398-415E-BF0F-A524F62FAE13_1001_0" unitRef="iso4217_USD"> 100000000 </us-gaap:CashAndCashEquivalentsFairValueDisclosure> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1270313x1575866" decimals="INF" id="id_6893637_1847E56B-691F-4492-AA99-DB71E47A2991_1001_0" unitRef="shares"> 796 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1270313x1591560" decimals="INF" id="id_6893637_50D5EF57-E29D-4D18-BA1F-56C3231ADD10_1001_0" unitRef="shares"> 17513 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares> | |||||||||||||||||||||
| <zfgn:MilestoneLiability contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1518235" decimals="-3" id="id_6893637_841F9BC0-F4DE-4BD7-9551-9CE7947D3B21_1001_0" unitRef="iso4217_USD"> 6700000 </zfgn:MilestoneLiability> | |||||||||||||||||||||
| <zfgn:MilestonePaymentAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1574444" decimals="-3" id="id_6893637_841F9BC0-F4DE-4BD7-9551-9CE7947D3B21_2001_1" unitRef="iso4217_USD"> 12250000 </zfgn:MilestonePaymentAmount> | |||||||||||||||||||||
| <zfgn:MilestonePaymentAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1574445" decimals="-3" id="id_6893637_841F9BC0-F4DE-4BD7-9551-9CE7947D3B21_3001_2" unitRef="iso4217_USD"> 12500000 </zfgn:MilestonePaymentAmount> | |||||||||||||||||||||
| <zfgn:LicensingFeesPerProductMaximum contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1574446" decimals="-3" id="id_6893637_841F9BC0-F4DE-4BD7-9551-9CE7947D3B21_4001_3" unitRef="iso4217_USD"> 1250000 </zfgn:LicensingFeesPerProductMaximum> | |||||||||||||||||||||
| <us-gaap:IncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1273333x1281276" decimals="-3" id="id_6893637_080DC78D-2B7B-4552-BD83-9A59C11CC1B4_1003_1" unitRef="iso4217_USD"> 1218000 </us-gaap:IncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1273334x1272538_1276401x1270422" decimals="INF" id="id_6893637_DF0B6285-2DFF-4639-8E35-FF3DE63140C4_1001_0" unitRef="shares"> 15077621 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityRemainingBorrowingCapacity contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1273334x1574584_1275460x1336760_1280323x1305126" decimals="-3" id="id_6893637_4E92D21F-EF93-4D35-B62A-915F13A61448_2002_2" unitRef="iso4217_USD"> 5000000 </us-gaap:LineOfCreditFacilityRemainingBorrowingCapacity> | |||||||||||||||||||||
| <zfgn:LineOfCreditFacilityDebtDefaultMinimumAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1275460x1336760" decimals="-3" id="id_6893637_11A84E45-A8A0-42DB-9FF5-22BCBD9E06DD_1001_0" unitRef="iso4217_USD"> 250000 </zfgn:LineOfCreditFacilityDebtDefaultMinimumAmount> | |||||||||||||||||||||
| <zfgn:PercentageThresholdSaleOfVotingEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1275460x1336760" decimals="2" id="id_6893637_94BAB2CF-33F8-4FCA-AD7D-63FDA4DA261A_2001_2" unitRef="pure"> 0.50 </zfgn:PercentageThresholdSaleOfVotingEquity> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityRemainingBorrowingCapacity contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1275460x1336760_1280323x1546828" decimals="-3" id="id_6893637_4E92D21F-EF93-4D35-B62A-915F13A61448_3002_1" unitRef="iso4217_USD"> 7500000 </us-gaap:LineOfCreditFacilityRemainingBorrowingCapacity> | |||||||||||||||||||||
| <us-gaap:LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280323x1450314" decimals="-3" id="id_6893637_147E8292-23A0-47C5-996C-29E6E0609A1E_1001_2" unitRef="iso4217_USD"> 2936000 </us-gaap:LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree> | |||||||||||||||||||||
| <us-gaap:LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280323x1450314" decimals="-3" id="id_6893637_147E8292-23A0-47C5-996C-29E6E0609A1E_1001_3" unitRef="iso4217_USD"> 3183000 </us-gaap:LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour> | |||||||||||||||||||||
| <us-gaap:LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280323x1450314" id="id_6893637_147E8292-23A0-47C5-996C-29E6E0609A1E_1001_0" unitRef="iso4217_USD" xsi:nil="true"/> | |||||||||||||||||||||
| <us-gaap:LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280323x1450314" decimals="-3" id="id_6893637_147E8292-23A0-47C5-996C-29E6E0609A1E_1001_1" unitRef="iso4217_USD"> 1381000 </us-gaap:LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo> | |||||||||||||||||||||
| <us-gaap:LongTermDebt contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280323x1450314" decimals="-3" id="id_6893637_147E8292-23A0-47C5-996C-29E6E0609A1E_1001_4" unitRef="iso4217_USD"> 7500000 </us-gaap:LongTermDebt> | |||||||||||||||||||||
| <us-gaap:CommonStockCapitalSharesReservedForFutureIssuance contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280964x1371249" decimals="INF" id="id_6893637_E3F53C9E-947E-4884-B13D-CB92B9126DCC_2001_0" unitRef="shares"> 2168221 </us-gaap:CommonStockCapitalSharesReservedForFutureIssuance> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280964x1382801" decimals="INF" id="id_6893637_F2F7AF9F-55B8-4319-AF07-D36C3EAEAAE5_3001_1" unitRef="shares"> 1889150 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized> | |||||||||||||||||||||
| <us-gaap:CommonStockCapitalSharesReservedForFutureIssuance contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280964x1382801" decimals="INF" id="id_6893637_F2F7AF9F-55B8-4319-AF07-D36C3EAEAAE5_3001_2" unitRef="shares"> 168221 </us-gaap:CommonStockCapitalSharesReservedForFutureIssuance> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant contextRef="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280964x1412684" decimals="INF" id="id_6893637_4DD495D8-9838-48A6-88DE-142E564AB71E_2003_3" unitRef="shares"> 265000 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue contextRef="eol_PE720058--14S-1-0007_STD_0_20091231_0" decimals="-3" id="id_6893637_D9783C13-7C5A-4B08-8CDD-36D0DAD430D6_1001_2" unitRef="iso4217_USD"> 216000 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_1001_2" unitRef="iso4217_USD_per_shares"> 0.75 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_1001_2" unitRef="shares"> 440301 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsValuationAllowance contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_2001_0" unitRef="iso4217_USD"> 12748000 </us-gaap:DeferredTaxAssetsValuationAllowance> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_1007_1000001" unitRef="iso4217_USD"> -27786000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsAtCarryingValue contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2001_26" unitRef="iso4217_USD"> 3717000 </us-gaap:CashAndCashEquivalentsAtCarryingValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1270313x1271210" decimals="2" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_1001_1" unitRef="iso4217_USD_per_shares"> 0.82 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_1001_1" unitRef="shares"> 38481 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1269588" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_1006_900001" unitRef="iso4217_USD"> -27843000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:SharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1270422" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_1003_600002" unitRef="shares"> 719957 </us-gaap:SharesOutstanding> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1270422" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_1003_700001" unitRef="iso4217_USD"> 1000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_1005_800001" unitRef="iso4217_USD"> 56000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_1001_400004" unitRef="shares"> 42947474 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital contextRef="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_1001_500003" unitRef="iso4217_USD"> 30453000 </us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_3001_6" unitRef="iso4217_USD_per_shares"> 1.19 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_3001_6" unitRef="shares"> 916094 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsValuationAllowance contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_1001_0" unitRef="iso4217_USD"> 18744000 </us-gaap:DeferredTaxAssetsValuationAllowance> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_3007_1000014" unitRef="iso4217_USD"> -40916000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsAtCarryingValue contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1001_26" unitRef="iso4217_USD"> 1467000 </us-gaap:CashAndCashEquivalentsAtCarryingValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0" decimals="-3" id="id_6893637_D9783C13-7C5A-4B08-8CDD-36D0DAD430D6_4001_3" unitRef="iso4217_USD"> 354000 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1270313x1271210" decimals="2" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_3001_5" unitRef="iso4217_USD_per_shares"> 0.82 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_3001_5" unitRef="shares"> 24548 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276400x1279561" decimals="INF" id="id_6893637_55CF9383-B0C7-4F00-BD93-5C30212E59B5_2001_0" unitRef="shares"> 8923884 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:SharesIssuedPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276400x1279561" decimals="INF" id="id_6893637_55CF9383-B0C7-4F00-BD93-5C30212E59B5_2001_1" unitRef="iso4217_USD_per_shares"> 0.9061 </us-gaap:SharesIssuedPricePerShare> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1269588" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_3006_900014" unitRef="iso4217_USD"> -41000000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:SharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1270422" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_3003_600015" unitRef="shares"> 719957 </us-gaap:SharesOutstanding> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1270422" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_3003_700014" unitRef="iso4217_USD"> 1000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_3005_800014" unitRef="iso4217_USD"> 83000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_3001_400017" unitRef="shares"> 54553369 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital contextRef="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_3001_500016" unitRef="iso4217_USD"> 40575000 </us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital> | |||||||||||||||||||||
| <us-gaap:CommonStockSharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_27" unitRef="shares"> 736026 </us-gaap:CommonStockSharesIssued> | |||||||||||||||||||||
| <us-gaap:CommonStockSharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_28" unitRef="shares"> 736026 </us-gaap:CommonStockSharesOutstanding> | |||||||||||||||||||||
| <us-gaap:CommonStockSharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_26" unitRef="shares"> 100000000 </us-gaap:CommonStockSharesAuthorized> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_5001_10" unitRef="iso4217_USD_per_shares"> 1.00 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_20" unitRef="shares"> 73991017 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_19" unitRef="shares"> 78372931 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_21" unitRef="shares"> 73991017 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:CommonStockParOrStatedValuePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_25" unitRef="iso4217_USD_per_shares"> 0.001 </us-gaap:CommonStockParOrStatedValuePerShare> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_5_6" unitRef="shares"> 11782007 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityParOrStatedValuePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_18" unitRef="iso4217_USD_per_shares"> 0.001 </us-gaap:TemporaryEquityParOrStatedValuePerShare> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_5001_10" unitRef="shares"> 591427 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_17" unitRef="iso4217_USD"> 62785000 </us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_5_5" unitRef="iso4217_USD"> 62785 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsValuationAllowance contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_11" unitRef="iso4217_USD"> 24006000 </us-gaap:DeferredTaxAssetsValuationAllowance> | |||||||||||||||||||||
| <us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_1_3" unitRef="iso4217_USD"> 22000 </us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_5_4" unitRef="iso4217_USD"> 63629000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:LiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_14" unitRef="iso4217_USD"> 2930000 </us-gaap:LiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:CommonStockValue contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_24" unitRef="iso4217_USD"> 1000 </us-gaap:CommonStockValue> | |||||||||||||||||||||
| <us-gaap:CommitmentsAndContingencies contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_16" unitRef="iso4217_USD" xsi:nil="true"/> | |||||||||||||||||||||
| <us-gaap:AccountsPayableCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_12" unitRef="iso4217_USD"> 1231000 </us-gaap:AccountsPayableCurrent> | |||||||||||||||||||||
| <us-gaap:RetainedEarningsAccumulatedDeficit contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_30" unitRef="iso4217_USD"> -54880000 </us-gaap:RetainedEarningsAccumulatedDeficit> | |||||||||||||||||||||
| <us-gaap:AdditionalPaidInCapitalCommonStock contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_29" unitRef="iso4217_USD"> 150000 </us-gaap:AdditionalPaidInCapitalCommonStock> | |||||||||||||||||||||
| <us-gaap:AccruedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_13" unitRef="iso4217_USD"> 1699000 </us-gaap:AccruedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_31" unitRef="iso4217_USD"> -54729000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:OtherAccruedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_1_3" unitRef="iso4217_USD"> 5000 </us-gaap:OtherAccruedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:LiabilitiesAndStockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_32" unitRef="iso4217_USD"> 10986000 </us-gaap:LiabilitiesAndStockholdersEquity> | |||||||||||||||||||||
| <us-gaap:AccruedProfessionalFeesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_1_2" unitRef="iso4217_USD"> 62000 </us-gaap:AccruedProfessionalFeesCurrent> | |||||||||||||||||||||
| <us-gaap:UnrecognizedTaxBenefits contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_77EEC73F-6FE8-407D-9D26-F2C1941E3E42_1001_0" unitRef="iso4217_USD"> 0 </us-gaap:UnrecognizedTaxBenefits> | |||||||||||||||||||||
| <us-gaap:Liabilities contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_15" unitRef="iso4217_USD"> 2930000 </us-gaap:Liabilities> | |||||||||||||||||||||
| <us-gaap:EmployeeRelatedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_1_0" unitRef="iso4217_USD"> 74000 </us-gaap:EmployeeRelatedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsAtCarryingValue contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_2" unitRef="iso4217_USD"> 9935000 </us-gaap:CashAndCashEquivalentsAtCarryingValue> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsLegalSettlements contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_7" unitRef="iso4217_USD"> 385000 </us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsLegalSettlements> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentNet contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_7" unitRef="iso4217_USD"> 32000 </us-gaap:PropertyPlantAndEquipmentNet> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_D9783C13-7C5A-4B08-8CDD-36D0DAD430D6_6001_4" unitRef="iso4217_USD"> 342000 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsGross contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_10" unitRef="iso4217_USD"> 24006000 </us-gaap:DeferredTaxAssetsGross> | |||||||||||||||||||||
| <us-gaap:PrepaidExpenseAndOtherAssetsCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_3" unitRef="iso4217_USD"> 389000 </us-gaap:PrepaidExpenseAndOtherAssetsCurrent> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_0" unitRef="iso4217_USD"> 46000 </us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsNetNoncurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_9" unitRef="iso4217_USD"> 23959000 </us-gaap:DeferredTaxAssetsNetNoncurrent> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsOther contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_1" unitRef="iso4217_USD"> 1000 </us-gaap:DeferredTaxAssetsOther> | |||||||||||||||||||||
| <us-gaap:DeferredOfferingCosts contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_E12C6233-3F75-4B3E-94F6-901AE37AB75B_1_0" unitRef="iso4217_USD"> 0 </us-gaap:DeferredOfferingCosts> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_8" unitRef="iso4217_USD"> 33000 </us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentGross contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_1_2" unitRef="iso4217_USD"> 54000 </us-gaap:PropertyPlantAndEquipmentGross> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsOperatingLossCarryforwards contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_5" unitRef="iso4217_USD"> 3209000 </us-gaap:DeferredTaxAssetsOperatingLossCarryforwards> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_4" unitRef="iso4217_USD"> 16676000 </us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment> | |||||||||||||||||||||
| <us-gaap:IncomeTaxesReceivableNoncurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_6" unitRef="iso4217_USD"> 630000 </us-gaap:IncomeTaxesReceivableNoncurrent> | |||||||||||||||||||||
| <us-gaap:Assets contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_9" unitRef="iso4217_USD"> 10986000 </us-gaap:Assets> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsNet contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_12" unitRef="iso4217_USD"> 0 </us-gaap:DeferredTaxAssetsNet> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsNetCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_2" unitRef="iso4217_USD"> 47000 </us-gaap:DeferredTaxAssetsNetCurrent> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxCreditCarryforwards contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1001_6" unitRef="iso4217_USD"> 3656000 </us-gaap:DeferredTaxAssetsTaxCreditCarryforwards> | |||||||||||||||||||||
| <us-gaap:AssetsCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_1_5" unitRef="iso4217_USD"> 10324000 </us-gaap:AssetsCurrent> | |||||||||||||||||||||
| <zfgn:AccruedResearchAndDevelopmentExpenseCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_1_1" unitRef="iso4217_USD"> 1558000 </zfgn:AccruedResearchAndDevelopmentExpenseCurrent> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsFairValueDisclosure contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1269038x1272304" decimals="-3" id="id_6893637_45F04C06-3E10-4F0A-AC0B-E9B7EC81711C_1001_0" unitRef="iso4217_USD"> 8001000 </us-gaap:CashAndCashEquivalentsFairValueDisclosure> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1270313x1271210" decimals="2" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_5001_9" unitRef="iso4217_USD_per_shares"> 0.82 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_5001_9" unitRef="shares"> 10615 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber> | |||||||||||||||||||||
| <us-gaap:IncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1273333x1281276" decimals="-3" id="id_6893637_D603F107-BDB3-43A7-98F8-16612F0F7189_3002_1" unitRef="iso4217_USD"> 630000 </us-gaap:IncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentGross contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276136x1274094" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_1001_1" unitRef="iso4217_USD"> 44000 </us-gaap:PropertyPlantAndEquipmentGross> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentGross contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276136x1279264" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_2001_0" unitRef="iso4217_USD"> 10000 </us-gaap:PropertyPlantAndEquipmentGross> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1269676" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_1_2" unitRef="shares"> 5363239 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1269676" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_1_1" unitRef="shares"> 5363239 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1269676" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_1_3" unitRef="shares"> 5363239 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1269676" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_1_6" unitRef="shares"> 854018 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1269676" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_1_5" unitRef="iso4217_USD"> 2222 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1269676" decimals="-3" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_1_4" unitRef="iso4217_USD"> 2250000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1279561" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_3_2" unitRef="shares"> 16732284 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1279561" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_3_1" unitRef="shares"> 16732284 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1279561" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_3_3" unitRef="shares"> 16732284 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1279561" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_3_6" unitRef="shares"> 2664376 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1279561" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_3_5" unitRef="iso4217_USD"> 15137 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1279561" decimals="-3" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_3_4" unitRef="iso4217_USD"> 15161000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281157" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_2_2" unitRef="shares"> 40266246 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281157" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_2_1" unitRef="shares"> 40266246 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281157" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_2_3" unitRef="shares"> 40266246 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281157" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_2_6" unitRef="shares"> 6411822 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281157" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_2_5" unitRef="iso4217_USD"> 30335 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281157" decimals="-3" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_2_4" unitRef="iso4217_USD"> 30402000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281158" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_4_2" unitRef="shares"> 11629248 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281158" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_4_1" unitRef="shares"> 16011162 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281158" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_4_3" unitRef="shares"> 11629248 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281158" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_4_6" unitRef="shares"> 1851791 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281158" decimals="INF" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_4_5" unitRef="iso4217_USD"> 15091 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281158" decimals="-3" id="id_6893637_E6C7F8E5-745D-41BB-B5F8-8E4537370B88_4_4" unitRef="iso4217_USD"> 15816000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1269588" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_7006_900031" unitRef="iso4217_USD"> -54880000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:SharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1270422" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_7003_600032" unitRef="shares"> 736026 </us-gaap:SharesOutstanding> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1270422" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_7003_700031" unitRef="iso4217_USD"> 1000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_7005_800031" unitRef="iso4217_USD"> 150000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_7001_400034" unitRef="shares"> 73991017 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital contextRef="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_7001_500033" unitRef="iso4217_USD"> 62785000 </us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital> | |||||||||||||||||||||
| <us-gaap:CommonStockSharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_27" unitRef="shares"> 729391 </us-gaap:CommonStockSharesIssued> | |||||||||||||||||||||
| <us-gaap:CommonStockSharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_28" unitRef="shares"> 729391 </us-gaap:CommonStockSharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_7001_15" unitRef="shares"> 1310330 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber> | |||||||||||||||||||||
| <us-gaap:CommonStockSharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_26" unitRef="shares"> 115000000 </us-gaap:CommonStockSharesAuthorized> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_7001_14" unitRef="iso4217_USD_per_shares"> 1.88 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_20" unitRef="shares"> 94483404 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_7001_16" unitRef="shares"> 657317 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_7001_16" unitRef="iso4217_USD_per_shares"> 1.26 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:PreferredStockSharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_2_29" unitRef="shares"> 0 </us-gaap:PreferredStockSharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_7001_15" unitRef="iso4217_USD_per_shares"> 1.88 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_19" unitRef="shares"> 99292610 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_21" unitRef="shares"> 94483404 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:CommonStockCapitalSharesReservedForFutureIssuance contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_580775B0-539D-4931-9B6A-7D626D2D770F_1001_0" unitRef="shares"> 16726699 </us-gaap:CommonStockCapitalSharesReservedForFutureIssuance> | |||||||||||||||||||||
| <us-gaap:CommonStockParOrStatedValuePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_25" unitRef="iso4217_USD_per_shares"> 0.001 </us-gaap:CommonStockParOrStatedValuePerShare> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_6_6" unitRef="shares"> 15045125 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:PreferredStockSharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_2_27" unitRef="shares"> 0 </us-gaap:PreferredStockSharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityParOrStatedValuePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_18" unitRef="iso4217_USD_per_shares"> 0.001 </us-gaap:TemporaryEquityParOrStatedValuePerShare> | |||||||||||||||||||||
| <us-gaap:PreferredStockParOrStatedValuePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_2_26" unitRef="iso4217_USD_per_shares"> 0.001 </us-gaap:PreferredStockParOrStatedValuePerShare> | |||||||||||||||||||||
| <us-gaap:PreferredStockSharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_2_28" unitRef="shares"> 0 </us-gaap:PreferredStockSharesIssued> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_7001_14" unitRef="shares"> 1310330 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_17" unitRef="iso4217_USD"> 103797000 </us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_6_5" unitRef="iso4217_USD"> 103797 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsValuationAllowance contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_11" unitRef="iso4217_USD"> 30357000 </us-gaap:DeferredTaxAssetsValuationAllowance> | |||||||||||||||||||||
| <us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_2_3" unitRef="iso4217_USD"> 34000 </us-gaap:AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_22" unitRef="iso4217_USD"> 104588000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:PreferredStockValue contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" id="id_6893637_1F67799A-6A63-444F-BA17-A822CEE151EA_2_25" unitRef="iso4217_USD" xsi:nil="true"/> | |||||||||||||||||||||
| <us-gaap:LiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_14" unitRef="iso4217_USD"> 2915000 </us-gaap:LiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:CommonStockValue contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_24" unitRef="iso4217_USD"> 1000 </us-gaap:CommonStockValue> | |||||||||||||||||||||
| <us-gaap:CommitmentsAndContingencies contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_16" unitRef="iso4217_USD" xsi:nil="true"/> | |||||||||||||||||||||
| <us-gaap:AccountsPayableCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_12" unitRef="iso4217_USD"> 2015000 </us-gaap:AccountsPayableCurrent> | |||||||||||||||||||||
| <us-gaap:RetainedEarningsAccumulatedDeficit contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_30" unitRef="iso4217_USD"> -68907000 </us-gaap:RetainedEarningsAccumulatedDeficit> | |||||||||||||||||||||
| <us-gaap:AdditionalPaidInCapitalCommonStock contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_29" unitRef="iso4217_USD"> 332000 </us-gaap:AdditionalPaidInCapitalCommonStock> | |||||||||||||||||||||
| <us-gaap:AccruedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_13" unitRef="iso4217_USD"> 900000 </us-gaap:AccruedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_31" unitRef="iso4217_USD"> -68574000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:OtherAccruedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_2_3" unitRef="iso4217_USD"> 39000 </us-gaap:OtherAccruedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesFutureMinimumPaymentsDue contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_A729E2D1-90EF-4464-85F0-E6A2CCDD3007_1_2" unitRef="iso4217_USD"> 64000 </us-gaap:OperatingLeasesFutureMinimumPaymentsDue> | |||||||||||||||||||||
| <us-gaap:LiabilityForUncertainTaxPositionsCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_3001_9" unitRef="iso4217_USD"> 0 </us-gaap:LiabilityForUncertainTaxPositionsCurrent> | |||||||||||||||||||||
| <us-gaap:LiabilitiesAndStockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_32" unitRef="iso4217_USD"> 38138000 </us-gaap:LiabilitiesAndStockholdersEquity> | |||||||||||||||||||||
| <us-gaap:AccruedProfessionalFeesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_2_2" unitRef="iso4217_USD"> 196000 </us-gaap:AccruedProfessionalFeesCurrent> | |||||||||||||||||||||
| <us-gaap:LineOfCredit contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="INF" id="id_6893637_4CE801B9-1EA5-4E64-88B1-F84D711F9F18_1002_1" unitRef="iso4217_USD"> 0 </us-gaap:LineOfCredit> | |||||||||||||||||||||
| <us-gaap:Liabilities contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_15" unitRef="iso4217_USD"> 2915000 </us-gaap:Liabilities> | |||||||||||||||||||||
| <us-gaap:EmployeeRelatedLiabilitiesCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_2_0" unitRef="iso4217_USD"> 49000 </us-gaap:EmployeeRelatedLiabilitiesCurrent> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesFutureMinimumPaymentsDueCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_A729E2D1-90EF-4464-85F0-E6A2CCDD3007_1_1" unitRef="iso4217_USD"> 64000 </us-gaap:OperatingLeasesFutureMinimumPaymentsDueCurrent> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsAtCarryingValue contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_2" unitRef="iso4217_USD"> 35517000 </us-gaap:CashAndCashEquivalentsAtCarryingValue> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsLegalSettlements contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_7" unitRef="iso4217_USD"> 790000 </us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsLegalSettlements> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentNet contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_7" unitRef="iso4217_USD"> 37000 </us-gaap:PropertyPlantAndEquipmentNet> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_D9783C13-7C5A-4B08-8CDD-36D0DAD430D6_8001_5" unitRef="iso4217_USD"> 10185000 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsGross contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_10" unitRef="iso4217_USD"> 30357000 </us-gaap:DeferredTaxAssetsGross> | |||||||||||||||||||||
| <us-gaap:PrepaidExpenseAndOtherAssetsCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_3" unitRef="iso4217_USD"> 224000 </us-gaap:PrepaidExpenseAndOtherAssetsCurrent> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_D9783C13-7C5A-4B08-8CDD-36D0DAD430D6_8001_6" unitRef="iso4217_USD"> 10185000 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_0" unitRef="iso4217_USD"> 18000 </us-gaap:DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsNetNoncurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_9" unitRef="iso4217_USD"> 30337000 </us-gaap:DeferredTaxAssetsNetNoncurrent> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsOther contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_1" unitRef="iso4217_USD"> 2000 </us-gaap:DeferredTaxAssetsOther> | |||||||||||||||||||||
| <us-gaap:DeferredOfferingCosts contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_E12C6233-3F75-4B3E-94F6-901AE37AB75B_2_0" unitRef="iso4217_USD"> 743000 </us-gaap:DeferredOfferingCosts> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_8" unitRef="iso4217_USD"> 91000 </us-gaap:DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentGross contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_2_2" unitRef="iso4217_USD"> 71000 </us-gaap:PropertyPlantAndEquipmentGross> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1 contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_D9783C13-7C5A-4B08-8CDD-36D0DAD430D6_8001_7" unitRef="iso4217_USD"> 5543000 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsOperatingLossCarryforwards contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_5" unitRef="iso4217_USD"> 4021000 </us-gaap:DeferredTaxAssetsOperatingLossCarryforwards> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_4" unitRef="iso4217_USD"> 19856000 </us-gaap:DeferredTaxAssetsInProcessResearchAndDevelopment> | |||||||||||||||||||||
| <us-gaap:Assets contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_9" unitRef="iso4217_USD"> 38138000 </us-gaap:Assets> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsNet contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_12" unitRef="iso4217_USD"> 0 </us-gaap:DeferredTaxAssetsNet> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsNetCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_2" unitRef="iso4217_USD"> 20000 </us-gaap:DeferredTaxAssetsNetCurrent> | |||||||||||||||||||||
| <us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_0D3FBD8F-6255-45A8-8308-08D5E46A5DE2_1001_0" unitRef="iso4217_USD"> 1334000 </us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxCreditCarryforwards contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_F245606F-4FBC-4C3A-9B17-401579F55214_1002_6" unitRef="iso4217_USD"> 5579000 </us-gaap:DeferredTaxAssetsTaxCreditCarryforwards> | |||||||||||||||||||||
| <us-gaap:IncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_4" unitRef="iso4217_USD"> 1617000 </us-gaap:IncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:OtherAssetsNoncurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_8" unitRef="iso4217_USD"> 743000 </us-gaap:OtherAssetsNoncurrent> | |||||||||||||||||||||
| <us-gaap:AssetsCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_98F42C96-BB8A-4E00-B861-2764292A8AF4_2_5" unitRef="iso4217_USD"> 37358000 </us-gaap:AssetsCurrent> | |||||||||||||||||||||
| <zfgn:OperatingLossCarryforwardsAdditional contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_3001_4" unitRef="iso4217_USD"> 16000 </zfgn:OperatingLossCarryforwardsAdditional> | |||||||||||||||||||||
| <zfgn:AccruedResearchAndDevelopmentExpenseCurrent contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0" decimals="-3" id="id_6893637_31D253A9-83A6-4F07-B31E-2967E7F87374_2_1" unitRef="iso4217_USD"> 616000 </zfgn:AccruedResearchAndDevelopmentExpenseCurrent> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsFairValueDisclosure contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1269038x1272304" decimals="-3" id="id_6893637_45F04C06-3E10-4F0A-AC0B-E9B7EC81711C_1002_0" unitRef="iso4217_USD"> 26501000 </us-gaap:CashAndCashEquivalentsFairValueDisclosure> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1270313x1274447" decimals="INF" id="id_6893637_DC7A4A31-9169-4848-A534-6A3F33DBD038_2_0" unitRef="shares"> 796 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1270313x1384152" decimals="INF" id="id_6893637_DC7A4A31-9169-4848-A534-6A3F33DBD038_1_0" unitRef="shares"> 17513 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber> | |||||||||||||||||||||
| <zfgn:MilestonePaymentAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1272610x1574444" decimals="-3" id="id_6893637_BDE66042-902C-4662-BE71-2EACAF46E319_1001_0" unitRef="iso4217_USD"> 18950000 </zfgn:MilestonePaymentAmount> | |||||||||||||||||||||
| <zfgn:MilestonePaymentAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1272610x1574445" decimals="-3" id="id_6893637_BDE66042-902C-4662-BE71-2EACAF46E319_2001_1" unitRef="iso4217_USD"> 12500000 </zfgn:MilestonePaymentAmount> | |||||||||||||||||||||
| <zfgn:LicensingFeesPerProductMaximum contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1272610x1574446" decimals="-3" id="id_6893637_BDE66042-902C-4662-BE71-2EACAF46E319_3001_2" unitRef="iso4217_USD"> 1250000 </zfgn:LicensingFeesPerProductMaximum> | |||||||||||||||||||||
| <us-gaap:IncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1273333x1281276" decimals="-3" id="id_6893637_D603F107-BDB3-43A7-98F8-16612F0F7189_3001_1" unitRef="iso4217_USD"> 1617000 </us-gaap:IncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentGross contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276136x1274094" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_1002_1" unitRef="iso4217_USD"> 44000 </us-gaap:PropertyPlantAndEquipmentGross> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentGross contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276136x1279264" decimals="-3" id="id_6893637_8A38DA2A-0204-4364-B352-B6CFBC18FA43_2002_0" unitRef="iso4217_USD"> 27000 </us-gaap:PropertyPlantAndEquipmentGross> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesFutureMinimumPaymentsDue contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276136x1509307" decimals="-3" id="id_6893637_974B82A8-83E7-4F80-B0D9-075E5FA84203_1003_0" unitRef="iso4217_USD"> 0 </us-gaap:OperatingLeasesFutureMinimumPaymentsDue> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_1_2" unitRef="shares"> 5363239 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:SharesIssuedPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="INF" id="id_6893637_5AF4EADB-C90E-4417-8D8C-7408B7AFB63F_1001_0" unitRef="iso4217_USD_per_shares"> 0.419463 </us-gaap:SharesIssuedPricePerShare> | |||||||||||||||||||||
| <us-gaap:PreferredStockRedemptionPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="8" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_6001_2" unitRef="iso4217_USD_per_shares"> 2.63422764 </us-gaap:PreferredStockRedemptionPricePerShare> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_1_1" unitRef="shares"> 5363239 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_1_3" unitRef="shares"> 5363239 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_1_6" unitRef="shares"> 854018 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_1_5" unitRef="iso4217_USD"> 2229 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676" decimals="-3" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_1_4" unitRef="iso4217_USD"> 2250000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_5_2" unitRef="shares"> 16110473 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:SharesIssuedPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="INF" id="id_6893637_5AF4EADB-C90E-4417-8D8C-7408B7AFB63F_2001_4" unitRef="iso4217_USD_per_shares"> 2.1725 </us-gaap:SharesIssuedPricePerShare> | |||||||||||||||||||||
| <us-gaap:PreferredStockRedemptionPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="4" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_7001_6" unitRef="iso4217_USD_per_shares"> 13.6433 </us-gaap:PreferredStockRedemptionPricePerShare> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_5_1" unitRef="shares"> 20919679 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_5_3" unitRef="shares"> 16110473 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_5_6" unitRef="shares"> 2565361 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_5_5" unitRef="iso4217_USD"> 34847 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310" decimals="-3" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_5_4" unitRef="iso4217_USD"> 35000000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_3_2" unitRef="shares"> 16732284 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:SharesIssuedPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="INF" id="id_6893637_5AF4EADB-C90E-4417-8D8C-7408B7AFB63F_3001_2" unitRef="iso4217_USD_per_shares"> 0.9061 </us-gaap:SharesIssuedPricePerShare> | |||||||||||||||||||||
| <us-gaap:PreferredStockRedemptionPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="6" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_8001_4" unitRef="iso4217_USD_per_shares"> 5.690308 </us-gaap:PreferredStockRedemptionPricePerShare> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_3_1" unitRef="shares"> 16732284 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_3_3" unitRef="shares"> 16732284 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_3_6" unitRef="shares"> 2664376 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_3_5" unitRef="iso4217_USD"> 15144 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561" decimals="-3" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_3_4" unitRef="iso4217_USD"> 15161000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_2_2" unitRef="shares"> 40266246 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:SharesIssuedPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="INF" id="id_6893637_5AF4EADB-C90E-4417-8D8C-7408B7AFB63F_4001_1" unitRef="iso4217_USD_per_shares"> 0.75503 </us-gaap:SharesIssuedPricePerShare> | |||||||||||||||||||||
| <us-gaap:PreferredStockRedemptionPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="7" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_9001_3" unitRef="iso4217_USD_per_shares"> 4.7415884 </us-gaap:PreferredStockRedemptionPricePerShare> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_2_1" unitRef="shares"> 40266246 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_2_3" unitRef="shares"> 40266246 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_2_6" unitRef="shares"> 6411822 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_2_5" unitRef="iso4217_USD"> 30351 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157" decimals="-3" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_2_4" unitRef="iso4217_USD"> 30402000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesIssued contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_4_2" unitRef="shares"> 16011162 </us-gaap:TemporaryEquitySharesIssued> | |||||||||||||||||||||
| <us-gaap:SharesIssuedPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="INF" id="id_6893637_5AF4EADB-C90E-4417-8D8C-7408B7AFB63F_5001_3" unitRef="iso4217_USD_per_shares"> 1.3592 </us-gaap:SharesIssuedPricePerShare> | |||||||||||||||||||||
| <us-gaap:PreferredStockRedemptionPricePerShare contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="6" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_10001_5" unitRef="iso4217_USD_per_shares"> 8.535776 </us-gaap:PreferredStockRedemptionPricePerShare> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_4_1" unitRef="shares"> 16011162 </us-gaap:TemporaryEquitySharesAuthorized> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_4_3" unitRef="shares"> 16011162 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_4_6" unitRef="shares"> 2549548 </us-gaap:ConvertiblePreferredStockSharesIssuedUponConversion> | |||||||||||||||||||||
| <us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="INF" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_4_5" unitRef="iso4217_USD"> 21226 </us-gaap:RedeemableNoncontrollingInterestEquityCarryingAmount> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityLiquidationPreference contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158" decimals="-3" id="id_6893637_8489F9AA-218F-4E49-BC39-36C7B1B4A0B6_4_4" unitRef="iso4217_USD"> 21775000 </us-gaap:TemporaryEquityLiquidationPreference> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1269588" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_11006_900045" unitRef="iso4217_USD"> -68907000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:SharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1270422" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_11003_600046" unitRef="shares"> 729391 </us-gaap:SharesOutstanding> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1270422" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_11003_700045" unitRef="iso4217_USD"> 1000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:StockholdersEquity contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_11005_800045" unitRef="iso4217_USD"> 332000 </us-gaap:StockholdersEquity> | |||||||||||||||||||||
| <us-gaap:TemporaryEquitySharesOutstanding contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_11001_400048" unitRef="shares"> 94483404 </us-gaap:TemporaryEquitySharesOutstanding> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_11001_500047" unitRef="iso4217_USD"> 103797000 </us-gaap:TemporaryEquityValueExcludingAdditionalPaidInCapital> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280651x1276398" decimals="-3" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_4001_6" unitRef="iso4217_USD"> 1322000 </us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch> | |||||||||||||||||||||
| <us-gaap:OperatingLossCarryforwards contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280651x1276398" decimals="-3" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_4001_1" unitRef="iso4217_USD"> 8226000 </us-gaap:OperatingLossCarryforwards> | |||||||||||||||||||||
| <us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280651x1280458" decimals="-3" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_5001_5" unitRef="iso4217_USD"> 4706000 </us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch> | |||||||||||||||||||||
| <us-gaap:OperatingLossCarryforwards contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280651x1280458" decimals="-3" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_5001_0" unitRef="iso4217_USD"> 10548000 </us-gaap:OperatingLossCarryforwards> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280964x1382801" decimals="INF" id="id_6893637_C07E9E4B-29B9-429E-AA64-BDD53907F426_1001_0" unitRef="shares"> 1889150 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280964x1382801" decimals="INF" id="id_6893637_C07E9E4B-29B9-429E-AA64-BDD53907F426_1001_1" unitRef="shares"> 371244 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant> | |||||||||||||||||||||
| <us-gaap:DebtInstrumentInterestRateStatedPercentage contextRef="eol_PE720058--14S-1-0007_STD_0_20131231_0_1281195x1275455" decimals="2" id="id_6893637_774955CB-9842-4BE3-917D-4AC1714BA884_4003_1" unitRef="pure"> 0.08 </us-gaap:DebtInstrumentInterestRateStatedPercentage> | |||||||||||||||||||||
| <zfgn:OperatingLeaseOptionForExtensionPeriod contextRef="eol_PE720058--14S-1-0007_STD_1_20140515_0_1273383x1591562" id="id_6893637_1F11D39F-569C-4418-B621-01C605579C88_1002_1"> P3Y </zfgn:OperatingLeaseOptionForExtensionPeriod> | |||||||||||||||||||||
| <us-gaap:AmortizationOfDebtDiscountPremium contextRef="eol_PE720058--14S-1-0007_STD_1_20140331_0_1275460x1336760_1280323x1450314" decimals="-3" id="id_6893637_2063124B-025E-46F9-A7B3-11669E59C004_1001_0" unitRef="iso4217_USD"> 114000 </us-gaap:AmortizationOfDebtDiscountPremium> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfSecuredDebt contextRef="eol_PE720058--14S-1-0007_STD_1_20140331_0_1275460x1336760_1280323x1450314" decimals="-3" id="id_6893637_4E92D21F-EF93-4D35-B62A-915F13A61448_1001_0" unitRef="iso4217_USD"> 7500000 </us-gaap:ProceedsFromIssuanceOfSecuredDebt> | |||||||||||||||||||||
| <us-gaap:PreferredStockConversionBasis contextRef="eol_PE720058--14S-1-0007_STD_1_20140605_0_1271378x1273350" id="id_6893637_CF8E653E-6741-4972-A4BC-A99B9DB4E8A0_1001_0"> 1-for-6.28 </us-gaap:PreferredStockConversionBasis> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesNewIssues contextRef="eol_PE720058--14S-1-0007_STD_1_20140624_0_1273334x1272538_1276401x1270422" decimals="INF" id="id_6893637_842A6724-7EB5-408F-A311-FADA31C8F756_1001_0" unitRef="shares"> 6900000 </us-gaap:StockIssuedDuringPeriodSharesNewIssues> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceInitialPublicOffering contextRef="eol_PE720058--14S-1-0007_STD_1_20140624_0_1273334x1272538_1276401x1270422" decimals="-3" id="id_6893637_842A6724-7EB5-408F-A311-FADA31C8F756_1001_2" unitRef="iso4217_USD"> 102672000 </us-gaap:ProceedsFromIssuanceInitialPublicOffering> | |||||||||||||||||||||
| <zfgn:InitialPublicOfferingCost contextRef="eol_PE720058--14S-1-0007_STD_1_20140624_0_1273334x1272538_1276401x1270422" decimals="-3" id="id_6893637_842A6724-7EB5-408F-A311-FADA31C8F756_1001_3" unitRef="iso4217_USD"> 2508000 </zfgn:InitialPublicOfferingCost> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardDiscountFromMarketPriceOfferingDate contextRef="eol_PE720058--14S-1-0007_STD_1_20140901_0_1269523x1275948_1280964x1412684" decimals="2" id="id_6893637_4DD495D8-9838-48A6-88DE-142E564AB71E_1002_2" unitRef="pure"> 0.85 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardDiscountFromMarketPriceOfferingDate> | |||||||||||||||||||||
| <zfgn:FirstOfferingPeriodStartDate contextRef="eol_PE720058--14S-1-0007_STD_1_20140901_0_1280964x1412684" id="id_6893637_4DD495D8-9838-48A6-88DE-142E564AB71E_2002_1"> 2014-09-01 </zfgn:FirstOfferingPeriodStartDate> | |||||||||||||||||||||
| <us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1 contextRef="eol_PE720058--14S-1-0007_STD_1_20140930_0" id="id_6893637_5AFB43F0-9D21-4B36-BE3D-A6B3CD7478BF_1_1"> P3Y4M24D </us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_12" unitRef="iso4217_USD"> -10871000 </us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="0" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_15" unitRef="shares"> 728862 </us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:EarningsPerShareBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="2" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_14" unitRef="iso4217_USD_per_shares"> -14.19 </us-gaap:EarningsPerShareBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="INF" id="id_6893637_D4283396-64A3-4317-81E2-67698D5DC014_2_2" unitRef="shares"> 79656195 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_22" unitRef="iso4217_USD"> 165000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossUnrealized contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_6" unitRef="iso4217_USD"> -169000 </us-gaap:ForeignCurrencyTransactionGainLossUnrealized> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_8" unitRef="iso4217_USD"> -160000 </us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets> | |||||||||||||||||||||
| <us-gaap:OperatingIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_5" unitRef="iso4217_USD"> -10019000 </us-gaap:OperatingIncomeLoss> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_9" unitRef="iso4217_USD"> -162000 </us-gaap:ForeignCurrencyTransactionGainLossBeforeTax> | |||||||||||||||||||||
| <us-gaap:NonoperatingIncomeExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_10" unitRef="iso4217_USD"> -162000 </us-gaap:NonoperatingIncomeExpense> | |||||||||||||||||||||
| <us-gaap:Revenues contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_0" unitRef="iso4217_USD"> 0 </us-gaap:Revenues> | |||||||||||||||||||||
| <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_14" unitRef="iso4217_USD"> 9000 </us-gaap:PaymentsToAcquirePropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_13" unitRef="iso4217_USD"> -10341000 </us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_11" unitRef="iso4217_USD"> -10181000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInIncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_9" unitRef="iso4217_USD"> 1230000 </us-gaap:IncreaseDecreaseInIncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_3" unitRef="iso4217_USD"> 252000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_29" unitRef="iso4217_USD"> 14000 </us-gaap:DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction> | |||||||||||||||||||||
| <us-gaap:OperatingExpenses contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_4" unitRef="iso4217_USD"> 10019000 </us-gaap:OperatingExpenses> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_2" unitRef="iso4217_USD"> 7038000 </us-gaap:ResearchAndDevelopmentExpense> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_24" unitRef="iso4217_USD"> -5090000 </us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesRentExpenseNet contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_44DABFB7-3E71-4DE6-8DE2-65A0A52DDB4A_2_0" unitRef="iso4217_USD"> 87000 </us-gaap:OperatingLeasesRentExpenseNet> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_12" unitRef="iso4217_USD"> 160000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:Depreciation contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_5" unitRef="iso4217_USD"> 8000 </us-gaap:Depreciation> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_23" unitRef="iso4217_USD"> 5790000 </us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_18" unitRef="iso4217_USD"> 5955000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:DefinedContributionPlanCostRecognized contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_90DADE2D-AAAF-4C98-844A-19931FE92F21_2_0" unitRef="iso4217_USD"> 20000 </us-gaap:DefinedContributionPlanCostRecognized> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccruedLiabilities contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_11" unitRef="iso4217_USD"> -171000 </us-gaap:IncreaseDecreaseInAccruedLiabilities> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_16" unitRef="iso4217_USD"> -9000 </us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:GeneralAndAdministrativeExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_2_3" unitRef="iso4217_USD"> 2981000 </us-gaap:GeneralAndAdministrativeExpense> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccountsPayable contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_2_10" unitRef="iso4217_USD"> 122000 </us-gaap:IncreaseDecreaseInAccountsPayable> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0_1268687x1276186" decimals="INF" id="id_6893637_D4283396-64A3-4317-81E2-67698D5DC014_1002_1" unitRef="shares"> 78372931 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0_1268687x1281225" decimals="INF" id="id_6893637_D4283396-64A3-4317-81E2-67698D5DC014_2002_0" unitRef="shares"> 1283264 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0_1270313x1271210_1276401x1270422" decimals="INF" id="id_6893637_6E8A6079-2658-4D6F-952B-856B5C8FFB0E_1001_0" unitRef="shares"> 6635 </us-gaap:StockRepurchasedAndRetiredDuringPeriodShares> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0_1274159x1269133" decimals="-3" id="id_6893637_D33320FF-60EB-4BEC-8834-BE1EE799939E_1002_1" unitRef="iso4217_USD"> 143000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0_1274159x1269570" decimals="-3" id="id_6893637_D33320FF-60EB-4BEC-8834-BE1EE799939E_2002_0" unitRef="iso4217_USD"> 109000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossUnrealized contextRef="eol_PE720058--14S-1-0007_STD_273_20130930_0_1280651x1574427" decimals="-3" id="id_6893637_080DC78D-2B7B-4552-BD83-9A59C11CC1B4_2002_0" unitRef="iso4217_USD"> -169000 </us-gaap:ForeignCurrencyTransactionGainLossUnrealized> | |||||||||||||||||||||
| <us-gaap:AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_550BD84A-B2BE-4A2C-85DB-ED4383804E39_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>3. Accrued Expenses</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Accrued expenses consisted of the following:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="76%" align="center" border="0"> <tr> <td width="65%"></td> <td valign="bottom" width="13%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="13%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center"> <b>September 30,</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center"> <b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2014</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued licensing milestone fees</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">6,700</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued research and development expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,759</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">616</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued payroll and related expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">741</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">49</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued professional fees</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">542</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">196</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued interest</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">51</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued other</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">92</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">39</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">9,885</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">900</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:CommitmentsAndContingenciesDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_77B4A9E4-D59B-4FB2-9475-F2C2055E8AF4_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>7. Commitments and Contingencies</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt"> <b>Leases</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> On May 15, 2014, the Company entered into a new lease for office space in Boston, Massachusetts, effective as of July 28, 2014, with a term expiring July 31, 2017 and an option to extend the lease for three additional years.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Future minimum lease payments for its operating leases as of September 30, 2014, are as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="68%" align="center" border="0"> <tr> <td width="89%"></td> <td valign="bottom" width="7%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom" nowrap="nowrap"> <p style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-BOTTOM: #000000 1pt solid; WIDTH: 92.45pt"> <b>Year Ending December 31,</b></p> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Remainder of 2014</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">57</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2015</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">229</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2016</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">235</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2017</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">139</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Total</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">660</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> During the nine months ended September 30, 2014 and 2013, the Company recognized $104 and $87, respectively, of rental expense related to office space.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Intellectual Property Licenses</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company has acquired exclusive rights to develop patented compounds and related know-how for beloranib under two licensing agreements with two third parties in the course of its research and development activities. The licensing rights obligate the Company to make payments to the licensors for license fees, milestones, license maintenance fees and royalties. The Company is also responsible for patent prosecution costs.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of September 30, 2014, the Company recorded a liability of $6,700 relating to milestones achieved in September 2014 upon the initiation of a first Phase 3 clinical trial. As of September 30, 2014, the Company is obligated to make additional milestone payments of up to $12,250 upon reaching certain pre-commercialization milestones, such as clinical trials and government approvals, and up to $12,500 upon reaching certain product commercialization milestones. Under one of the license agreements, the Company is also obligated to pay up to $1,250 with respect to each subsequent licensed product, if any, that is a new chemical entity. In addition, the Company will owe single-digit royalties on sales of commercial products developed using these licensed technologies, if any. The Company is also obligated to pay to the licensors a percentage of fees received if and when the Company sublicenses the technology. As of September 30, 2014, the Company has not yet developed a commercial product using the licensed technologies and it has not entered into any sublicense agreements for the technologies.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Indemnification Agreements</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> In the ordinary course of business, the Company may provide indemnification of varying scope and terms to vendors, lessors, business partners, and other parties with respect to certain matters including, but not limited to, losses arising out of breach of such agreements or from intellectual property infringement claims made by third parties. In addition, the Company has entered into indemnification agreements with members of its board of directors that will require the Company, among other things, to indemnify them against certain liabilities that may arise by reason of their status or service as directors or officers. The maximum potential amount of future payments the Company could be required to make under these indemnification agreements is, in many cases, unlimited. To date, the Company has not incurred any material costs as a result of such indemnifications. The Company does not believe that the outcome of any claims under indemnification arrangements will have a material effect on its financial position, results of operations or cash flows, and it has not accrued any liabilities related to such obligations in its consolidated financial statements as of September 30, 2014.</p> </div> </us-gaap:CommitmentsAndContingenciesDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:DebtDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_D1AF56E2-752E-4AD6-A7DE-2B258DE3E6C1_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>4. Notes Payable</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> On March 31, 2014, the Company entered into a loan and security agreement with Oxford Finance LLC and Midcap Financial (the “Credit Facility”). The Credit Facility provides for initial borrowings of $7,500 under a term loan (“Term Loan A”) and additional borrowings of up to $12,500 under other term loans, for a maximum of $20,000. On March 31, 2014, the Company received proceeds of $7,500 from the issuance of promissory notes under the Term Loan A. Of the additional $12,500 amount that was available, $7,500 (“Term Loan B”) was available to be drawn down until September 30, 2014 and $5,000 (“Term Loan C”) was available to be drawn down for a 30-day period upon the completion of the Company’s IPO that occurred in June 2014. The Company elected not to draw down Term Loan B or Term Loan C and these amounts are no longer available to the Company. All promissory notes issued under the Credit Facility are collateralized by substantially all of the Company’s personal property, other than its intellectual property.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Upon entering into this Credit Facility, the Company was obligated to make monthly, interest-only payments on any term loans funded under the Credit Facility until December 1, 2014 and, thereafter, to pay 36 consecutive, equal monthly installments of principal and interest from January 1, 2015 through December 1, 2017. As per the terms of the agreement, in June 2014, upon the completion of the Company’s IPO, the term of monthly, interest-only payments were extended until June 1, 2015. Outstanding term loans under the Credit Facility bear interest at an annual rate of 8.1%. In addition, a final payment equal to 6.0% of any amounts drawn under the Credit Facility is due upon the earlier of the maturity date, acceleration of the term loans or prepayment of all or part of the term loans. The Company accrues the amount due relating to Term Loan A of $450, to outstanding debt by charges to interest expense using the effective-interest method from the date of issuance through the maturity date.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Term Loan A was recorded in the balance sheet net of debt discount of $114 that was related to fees assessed by the lender at the time of borrowing. The debt discount is being accreted to the principal amount of the debt. In addition, deferred financing costs of $49 are being amortized to interest expense using the effective-interest method over the same term. For the nine months ended September 30, 2014, the Company recorded additional interest expense of $36 related the accretion of the debt discount and amortization of deferred financing costs.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company was obligated to pay a separate fee upon any IPO; a sale of substantially all of the Company’s assets; or a merger, reorganization or sale of the Company’s voting equity securities where existing voting stockholders hold less than 50% of voting equity securities after such transaction. As of September 30, 2014, the Company recorded interest expense of $225 relating to the fee payable upon completion of the Company’s IPO in June 2014.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> There are no financial covenants associated with the debt facility; however, there are negative covenants restricting the Company’s activities, including limitations on dispositions, mergers or acquisitions; encumbering or granting a security interest in its intellectual property; incurring indebtedness or liens; paying dividends; making certain investments; and certain other business transactions.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Credit Facility also includes events of default, the occurrence and continuation of any of which provides the lenders the right to exercise remedies against the Company and the collateral securing the loans under the Credit Facility, including cash. These events of default include, among other things, failure to pay any amounts due under the Credit Facility, insolvency, the occurrence of a material adverse event, the occurrence of any default under certain other indebtedness and a final judgment against the Company in an amount greater than $250.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Estimated future principal payments due under the Term Loan A are as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="68%" align="center" border="0"> <tr> <td width="86%"></td> <td valign="bottom" width="8%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom" nowrap="nowrap"> <p style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-BOTTOM: #000000 1pt solid; WIDTH: 95.55pt"> <b>Years Ending December 31,</b></p> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Remainder of 2014</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2015</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,381</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2016</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,936</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2017</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">3,183</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Total</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">7,500</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> During the nine months ended September 30, 2014, the Company recognized $658 of interest expense related to the Credit Facility.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company had no debt outstanding as of December 31, 2013.</p> </div> </us-gaap:DebtDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:EarningsPerSharePolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_7DF300D0-59D0-4419-96B6-E78DE451710B_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>Net Income (Loss) Per Share</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Upon the closing of the Company’s IPO in June 2014, all of the Company’s outstanding redeemable convertible preferred shares were converted into shares of common stock. Prior to this conversion, the Company followed the two-class method when computing net income (loss) per share as the Company had issued shares that meet the definition of participating securities. The two-class method determines net income (loss) per share for each class of common and participating securities according to dividends declared or accumulated and participation rights in undistributed earnings. The two-class method requires income available to common shareholders for the period to be allocated between common and participating securities based upon their respective rights to receive dividends as if all income for the period had been distributed. The Company’s redeemable convertible preferred shares contractually entitled the holders of such shares to participate in dividends, but did not contractually require the holders of such shares to participate in losses of the Company. Accordingly, the two-class method did not apply for periods in which the Company reported a net loss or a net loss attributable to common shareholders resulting from dividends or accretion related to its redeemable convertible preferred shares.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Basic net income (loss) per share attributable to common shareholders is computed by dividing the net income (loss) attributable to common shareholders by the weighted average number of common shares outstanding for the period. Diluted net income (loss) per share attributable to common shareholders is computed by dividing the diluted net income (loss) attributable to common shareholders by the weighted average number of common shares, including potential dilutive common shares assuming the dilutive effect of outstanding stock options and unvested restricted common shares, as determined using the treasury stock method. For periods in which the Company has reported net losses, diluted net loss per common share attributable to common shareholders is the same as basic net loss per common share attributable to common shareholders, since dilutive common shares are not assumed to have been issued if their effect is antidilutive.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company reported a net loss attributable to common stockholders for the nine months ended September 30, 2014 and 2013.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The following common stock equivalents, outstanding as of September 30, 2014 and 2013, were excluded from the computation of diluted net loss per share for the nine months ended September 30, 2014 and 2013 because they had an anti-dilutive impact:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="92%" align="center" border="0"> <tr> <td width="75%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"><b>As of September 30,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2014</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 1pt"> <td height="8"></td> <td height="8" colspan="4"></td> <td height="8" colspan="4"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Options to purchase common stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,839,895</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,283,264</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">78,372,931</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Total options and redeemable convertible preferred stock exercisable or convertible into common stock</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,839,895</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">79,656,195</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:EarningsPerSharePolicyTextBlock> | |||||||||||||||||||||
| <dei:DocumentType contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_E59E08B7-2841-4BB0-9352-07743341B6BC_1_0"> S-1 </dei:DocumentType> | |||||||||||||||||||||
| <dei:EntityRegistrantName contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_2C18E821-2E88-4AC1-AB9B-DF854F9E6FC7_1_1"> Zafgen, Inc. </dei:EntityRegistrantName> | |||||||||||||||||||||
| <dei:TradingSymbol contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_2C18E821-2E88-4AC1-AB9B-DF854F9E6FC7_1_0"> ZFGN </dei:TradingSymbol> | |||||||||||||||||||||
| <us-gaap:ComprehensiveIncomePolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_75D79CB7-953A-41D4-9EC5-F0F68381A746_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Comprehensive Loss</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Comprehensive loss includes net loss as well as other changes in stockholders’ equity (deficit) that result from transactions and economic events other than those with stockholders. For the nine months ended September 30, 2014 and 2013, there was no difference between net loss and comprehensive loss.</p> </div> </us-gaap:ComprehensiveIncomePolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:IncomeTaxPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_D692CA59-6848-45EF-83B4-D7265F1989AF_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Income Taxes</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company accounts for income taxes using the asset and liability method, which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been recognized in the consolidated financial statements or in the Company’s tax returns. Deferred taxes are determined based on the difference between the financial statement and tax basis of assets and liabilities using enacted tax rates in effect in the years in which the differences are expected to reverse. Changes in deferred tax assets and liabilities are recorded in the provision for income taxes. The Company assesses the likelihood that its deferred tax assets will be recovered from future taxable income and, to the extent it believes, based upon the weight of available evidence, that it is more likely than not that all or a portion of deferred tax assets will not be realized, a valuation allowance is established through a charge to income tax expense. Potential for recovery of deferred tax assets is evaluated by estimating the future taxable profits expected and considering prudent and feasible tax planning strategies.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company accounts for uncertainty in income taxes recognized in the consolidated financial statements by applying a two-step process to determine the amount of tax benefit to be recognized. First, the tax position must be evaluated to determine the likelihood that it will be sustained upon external examination by the taxing authorities. If the tax position is deemed more-likely-than-not to be sustained, the tax position is then assessed to determine the amount of benefit to recognize in the consolidated financial statements. The amount of the benefit that may be recognized is the largest amount that has a greater than 50% likelihood of being realized upon ultimate settlement. The provision for income taxes includes the effects of any resulting tax reserves, or unrecognized tax benefits, that are considered appropriate as well as the related net interest and penalties.</p> </div> </us-gaap:IncomeTaxPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_CE360524-DDD7-47D3-9DBD-DC86784FDFDE_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The following common stock equivalents, outstanding as of September 30, 2014 and 2013, were excluded from the computation of diluted net loss per share for the nine months ended September 30, 2014 and 2013 because they had an anti-dilutive impact:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="92%" align="center" border="0"> <tr> <td width="75%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"><b>As of September 30,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2014</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 1pt"> <td height="8"></td> <td height="8" colspan="4"></td> <td height="8" colspan="4"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Options to purchase common stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,839,895</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,283,264</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">78,372,931</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Total options and redeemable convertible preferred stock exercisable or convertible into common stock</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,839,895</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">79,656,195</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock> | |||||||||||||||||||||
| <dei:EntityFilerCategory contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_2C18E821-2E88-4AC1-AB9B-DF854F9E6FC7_1_3"> Non-accelerated Filer </dei:EntityFilerCategory> | |||||||||||||||||||||
| <dei:EntityIncorporationDateOfIncorporation contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_003A0F41-4B0F-490B-A0CD-A2042210751C_1_0"> 2005-11-22 </dei:EntityIncorporationDateOfIncorporation> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_12" unitRef="iso4217_USD"> -16527000 </us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_29FCC431-9EF9-4A89-86A5-04C67401A349_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company recorded stock-based compensation expense related to stock options and restricted common stock in the following expense categories of its statements of operations:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="92%" align="center" border="0"> <tr> <td width="84%"></td> <td valign="bottom" width="5%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="5%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="6" align="center"> <b>Nine Months Ended</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"><b>September 30,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2014</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Research and development</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">259</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">109</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> General and administrative</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">651</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">143</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">910</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">252</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_35E48A67-34B7-42EF-889A-7ED75D0F968E_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Accrued expenses consisted of the following:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="76%" align="center" border="0"> <tr> <td width="65%"></td> <td valign="bottom" width="13%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="13%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center"> <b>September 30,</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center"> <b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2014</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued licensing milestone fees</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">6,700</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued research and development expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,759</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">616</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued payroll and related expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">741</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">49</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued professional fees</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">542</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">196</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued interest</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">51</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued other</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">92</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">39</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">9,885</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">900</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock> | |||||||||||||||||||||
| <us-gaap:UseOfEstimates contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_60AED135-D8E8-49D3-8CDF-4B31C04FE45B_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt"> <b>Use of Estimates</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the consolidated financial statements, and the reported amounts of expenses during the reporting periods. Significant estimates and assumptions reflected in these consolidated financial statements include, but are not limited to, the accrual of research and development expenses and the valuation of common stock prior to the IPO and stock-based awards. Estimates are periodically reviewed in light of changes in circumstances, facts and experience. Actual results could differ from the Company’s estimates.</p> </div> </us-gaap:UseOfEstimates> | |||||||||||||||||||||
| <us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="0" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_15" unitRef="shares"> 8618793 </us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted> | |||||||||||||||||||||
| <dei:DocumentPeriodEndDate contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_E59E08B7-2841-4BB0-9352-07743341B6BC_1_2"> 2014-09-30 </dei:DocumentPeriodEndDate> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_B6FB4D9E-D2DE-4D38-A92B-4F2C14121C1F_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Cash Equivalents</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company considers all short-term, highly liquid investments with original maturities of ninety days or less at acquisition date to be cash equivalents. Cash equivalents, which consist of money market accounts, are stated at fair value.</p> </div> </us-gaap:CashAndCashEquivalentsPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:DefinedContributionPlanEmployerMatchingContributionPercent contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="2" id="id_6893637_BD603723-C5A1-4E68-975E-17FD86E4B626_1_0" unitRef="pure"> 0.02 </us-gaap:DefinedContributionPlanEmployerMatchingContributionPercent> | |||||||||||||||||||||
| <us-gaap:IntangibleAssetsFiniteLivedPolicy contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_D515ADDD-107A-4E20-B0ED-271A112A93A8_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Patent Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> All patent-related costs incurred in connection with filing and prosecuting patent applications are recorded as general and administrative expenses as incurred, as recoverability of such expenditures is uncertain.</p> </div> </us-gaap:IntangibleAssetsFiniteLivedPolicy> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_2B52CE85-E574-4DB8-A385-10B0E691241A_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Property and Equipment</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Property and equipment are stated at cost less accumulated depreciation. Depreciation expense is recognized using the straight-line method over a five-year estimated useful life for both furniture and fixtures and office equipment. Expenditures for repairs and maintenance of assets are charged to expense as incurred. Upon retirement or sale, the cost and related accumulated depreciation of assets disposed of are removed from the accounts and any resulting gain or loss is included in loss from operations.</p> </div> </us-gaap:PropertyPlantAndEquipmentPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentUsefulLife contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_460E9ED1-6528-4B0B-9B60-F7B896F2DCF3_1_0"> P5Y </us-gaap:PropertyPlantAndEquipmentUsefulLife> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentExpensePolicy contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_2B1C5D79-7348-4E7F-A2BF-86020A488EFD_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Research and Development Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Research and development costs are expensed as incurred. Included in research and development expenses are wages, stock-based compensation and benefits of employees, third-party license fees and milestones and other operational costs related to the Company’s research and development activities, including facility-related expenses and external costs of outside vendors engaged to conduct both pre-clinical studies and clinical trials. The Company records research and development expenses net of any research and development tax incentives the Company is entitled to receive from government authorities.</p> </div> </us-gaap:ResearchAndDevelopmentExpensePolicy> | |||||||||||||||||||||
| <us-gaap:StockholdersEquityNoteDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_811A1E67-2D8D-47BD-91C3-98260AA841BD_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>5. Stockholders’ Equity</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> On June 5, 2014, the Company effected a 1-for-6.28 reverse stock split of its issued and outstanding shares of common stock and a proportional adjustment to the existing conversion ratios for each series of redeemable convertible preferred stock. Accordingly, all share and per share amounts for all periods presented in these consolidated financial statements and notes thereto have been adjusted retroactively, where applicable, to reflect this reverse stock split and adjustment of the redeemable convertible preferred stock conversion ratios.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> On June 24, 2014, the Company completed an IPO of its common stock, which resulted in the sale of 6,900,000 shares at a price of $16.00 per share. The Company received net proceeds from the IPO of $102,672 based upon the price of $16.00 per share and after deducting underwriting discounts and commissions paid by the Company. The Company also incurred offering costs of $2,508 related to the IPO.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Upon closing of the IPO, all outstanding shares of the Company’s redeemable convertible preferred stock were converted into 15,077,621 shares of common stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of September 30, 2014, the Company’s Certificate of Incorporation, as amended and restated, authorizes the Company to issue 5,000,000 shares of $0.001 par value preferred stock. The rights, preferences, restrictions, qualifications and limitations of such stock are to be determined by the Company’s board of directors.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of September 30, 2014 and December 31, 2013, the Company’s Certificate of Incorporation, as amended and restated, authorizes the Company to issue 115,000,000 shares of $0.001 par value common stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> During the nine months ended September 30, 2013, the Company reacquired 6,635 shares of restricted common stock, at cost, that were forfeited by a former employee.</p> </div> </us-gaap:StockholdersEquityNoteDisclosureTextBlock> | |||||||||||||||||||||
| <dei:AmendmentFlag contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_E59E08B7-2841-4BB0-9352-07743341B6BC_1_1"> false </dei:AmendmentFlag> | |||||||||||||||||||||
| <us-gaap:BusinessDescriptionAndBasisOfPresentationTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_14EB5CFA-3266-4590-A31F-7D9C10F61CA9_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt"> <b>1. Nature of the Business and Basis of Presentation</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Zafgen, Inc. (the “Company”) was incorporated on November 22, 2005 under the laws of the State of Delaware. The Company is a biopharmaceutical company dedicated to significantly improving the health and well-being of patients affected by obesity. Beloranib, the Company’s lead product candidate, is a novel, first-in-class, twice-weekly subcutaneous injection being developed for the treatment of multiple indications, including obesity and hyperphagia in Prader-Willi syndrome patients, hypothalamic injury-associated obesity including craniopharyngioma-associated obesity, and severe obesity in the general population. Since its inception, the Company has devoted substantially all of its efforts to research and development, recruiting management, acquiring operating assets and raising capital.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company is subject to risks common to companies in the biotechnology industry including, but not limited to, new technological innovations, protection of proprietary technology, dependence on key personnel, compliance with government regulations and the need to obtain additional financing. Product candidates currently under development will require significant additional research and development efforts, including extensive pre-clinical and clinical testing and regulatory approval, prior to commercialization. These efforts require significant amounts of additional capital, adequate personnel infrastructure, and extensive compliance-reporting capabilities.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company’s product candidates are all in the development stage. There can be no assurance that the Company’s research and development will be successfully completed, that adequate protection for the Company’s intellectual property will be obtained, that any products developed will obtain necessary government regulatory approval or that any approved products will be commercially viable. Even if the Company’s product development efforts are successful, it is uncertain when, if ever, the Company will generate significant revenue from product sales. The Company operates in an environment of rapid change in technology and substantial competition from pharmaceutical and biotechnology companies. In addition, the Company is dependent upon the services of its employees and consultants.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries Zafgen Securities Corporation, Zafgen Australia Pty Limited, and Zafgen Animal Health, LLC. All significant intercompany balances and transactions have been eliminated.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The accompanying consolidated financial statements have been prepared in conformity with accounting principles generally accepted in the United States of America (“GAAP”).</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> On June 24, 2014, the Company completed an initial public offering (“IPO”) of its common stock, which resulted in the sale of 6,900,000 shares at a price of $16.00 per share. The Company received net proceeds from the IPO of approximately $102,672 based upon the price of $16.00 per share and after deducting underwriting discounts and commissions paid by the Company. The Company also incurred offering costs of $2,508 related to the IPO.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Unaudited Interim Financial Information</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The consolidated balance sheet at December 31, 2013 was derived from audited financial statements, but does not include all disclosures required by GAAP. The accompanying unaudited consolidated financial statements as of September 30, 2014, and for the nine months ended September 30, 2014 and 2013, have been prepared by the Company, pursuant to the rules and regulations of the SEC for interim financial statements. Certain information and footnote disclosures normally included in financial statements prepared in accordance with GAAP have been condensed or omitted pursuant to such rules and regulations. However, the Company believes that the disclosures are adequate to make the information presented not misleading. These consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements and the notes thereto for the year ended December 31, 2013. In the opinion of management, all adjustments, consisting only of normal recurring adjustments necessary for a fair statement of the Company’s consolidated financial position as of September 30, 2014 and consolidated results of operations and consolidated cash flows for the nine months ended September 30, 2014 and 2013 have been made. The results for the nine months ended September 30, 2014 are not necessarily indicative of the results that may be expected for the year ending December 31, 2014, any other interim periods, or any future year or period.</p> </div> </us-gaap:BusinessDescriptionAndBasisOfPresentationTextBlock> | |||||||||||||||||||||
| <us-gaap:DeferredChargesPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_DE076816-653D-4054-B64F-22A9C34B2D6F_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Deferred Offering Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company capitalizes certain legal, accounting and other third-party fees that are directly associated with in-process equity financings as other assets until such financings are consummated. After consummation of the equity financing, these costs are recorded in stockholders’ equity (deficit) as a reduction of additional paid-in capital generated as a result of the offering or as a reduction to the carrying value of preferred stock issued. As of December 31, 2013, the Company had recorded $743 of deferred offering costs, included in other assets in the accompanying consolidated balance sheet, in contemplation of the Company’s IPO of its common stock, which closed in June 2014. The Company has no deferred offering costs as of September 30, 2014.</p> </div> </us-gaap:DeferredChargesPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:ResearchDevelopmentAndComputerSoftwareDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_B787D594-06B9-40A1-AE96-B3B6CD9B6533_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>9. Australia Research and Development Tax Incentive</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company’s wholly owned subsidiary, Zafgen Australia Pty Limited, which conducts core research and development activities on behalf of the Company, is eligible to receive a 45% refundable tax incentive for qualified research and development activities. For the nine months ended September 30, 2014 and 2013, $368 and $1,230, respectively, was recorded as a reduction to research and development expenses in the consolidated statements of operations. These amounts represented 45% of the Company’s qualified research and development spending in Australia. The refund is denominated in Australian dollars and, therefore, the related receivable is re-measured into U.S. dollars as of each reporting date. For the nine months ended September 30, 2014 and 2013, the Company recorded in its consolidated statements of operations unrealized foreign currency exchange (gains) losses of $31 and $169, respectively, related to this tax incentive receivable. As of September 30, 2014 and December 31, 2013, the Company’s tax incentive receivable from the Australian government was $1,218 and $1,617, respectively.</p> </div> </us-gaap:ResearchDevelopmentAndComputerSoftwareDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_15315C62-980B-4F0A-B8A4-E73EC3215276_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Future minimum lease payments for its operating leases as of September 30, 2014, are as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="68%" align="center" border="0"> <tr> <td width="89%"></td> <td valign="bottom" width="7%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom" nowrap="nowrap"> <p style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-BOTTOM: #000000 1pt solid; WIDTH: 92.45pt"> <b>Year Ending December 31,</b></p> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Remainder of 2014</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">57</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2015</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">229</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2016</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">235</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2017</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">139</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Total</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">660</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfMaturitiesOfLongTermDebtTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_EE39BEC7-03CA-46C5-82BE-DFC54B6F0C83_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Estimated future principal payments due under the Term Loan A are as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="68%" align="center" border="0"> <tr> <td width="86%"></td> <td valign="bottom" width="8%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom" nowrap="nowrap"> <p style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-BOTTOM: #000000 1pt solid; WIDTH: 95.55pt"> <b>Years Ending December 31,</b></p> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Remainder of 2014</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2015</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,381</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2016</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,936</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2017</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">3,183</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Total</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">7,500</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfMaturitiesOfLongTermDebtTableTextBlock> | |||||||||||||||||||||
| <us-gaap:SignificantAccountingPoliciesTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_CBF820A4-D20A-49F1-BEAD-BFA505054F8C_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>2. Summary of Significant Accounting Policies</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Use of Estimates</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the consolidated financial statements, and the reported amounts of expenses during the reporting periods. Significant estimates and assumptions reflected in these consolidated financial statements include, but are not limited to, the accrual of research and development expenses and the valuation of common stock prior to the IPO and stock-based awards. Estimates are periodically reviewed in light of changes in circumstances, facts and experience. Actual results could differ from the Company’s estimates.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Cash Equivalents</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company considers all short-term, highly liquid investments with original maturities of ninety days or less at acquisition date to be cash equivalents. Cash equivalents, which consist of money market accounts, are stated at fair value.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Concentration of Credit Risk and of Significant Suppliers</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Financial instruments that potentially expose the Company to concentrations of credit risk consist primarily of cash and cash equivalents. The Company has all cash and cash equivalents balances at one accredited financial institution, in amounts that exceed federally insured limits. The Company does not believe that it is subject to unusual credit risk beyond the normal credit risk associated with commercial banking relationships.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company is dependent on third-party manufacturers to supply products for research and development activities in its programs. In particular, the Company relies and expects to continue to rely on a small number of manufacturers to supply it with its requirements for the active pharmaceutical ingredients and formulated drugs related to these programs. These programs could be adversely affected by a significant interruption in the supply of active pharmaceutical ingredients and formulated drugs.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Fair Value Measurements</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Certain assets and liabilities are carried at fair value under GAAP. Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. Financial assets and liabilities carried at fair value are to be classified and disclosed in one of the following three levels of the fair value hierarchy, of which the first two are considered observable and the last is considered unobservable:</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 6pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 1—Quoted prices in active markets for identical assets or liabilities.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 6pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 2—Observable inputs (other than Level 1 quoted prices) such as quoted prices in active markets for similar assets or liabilities, quoted prices in markets that are not active for identical or similar assets or liabilities, or other inputs that are observable or can be corroborated by observable market data.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 6pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 3—Unobservable inputs that are supported by little or no market activity and that are significant to determining the fair value of the assets or liabilities, including pricing models, discounted cash flow methodologies and similar techniques.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company’s cash equivalents of $100,000 and $26,501 as of September 30, 2014 and December 31, 2013, respectively, were carried at fair value based on quoted prices in active markets, a Level 1 measurement. The carrying values of accounts payable and accrued expenses approximate their fair value due to the short-term nature of these liabilities. The Company’s carrying value of outstanding debt issued in the first quarter of 2014 approximates fair value based on the recent execution date of the credit facility agreement, and is considered a Level 2 measurement.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Deferred Offering Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company capitalizes certain legal, accounting and other third-party fees that are directly associated with in-process equity financings as other assets until such financings are consummated. After consummation of the equity financing, these costs are recorded in stockholders’ equity (deficit) as a reduction of additional paid-in capital generated as a result of the offering or as a reduction to the carrying value of preferred stock issued. As of December 31, 2013, the Company had recorded $743 of deferred offering costs, included in other assets in the accompanying consolidated balance sheet, in contemplation of the Company’s IPO of its common stock, which closed in June 2014. The Company has no deferred offering costs as of September 30, 2014.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Property and Equipment</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Property and equipment are stated at cost less accumulated depreciation. Depreciation expense is recognized using the straight-line method over a five-year estimated useful life for both furniture and fixtures and office equipment. Expenditures for repairs and maintenance of assets are charged to expense as incurred. Upon retirement or sale, the cost and related accumulated depreciation of assets disposed of are removed from the accounts and any resulting gain or loss is included in loss from operations.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Impairment of Long-Lived Assets</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Long-lived assets consist of property and equipment. Long-lived assets to be held and used are tested for recoverability whenever events or changes in business circumstances indicate that the carrying amount of the assets may not be fully recoverable. Factors that the Company considers in deciding when to perform an impairment review include significant underperformance of the business in relation to expectations, significant negative industry or economic trends, and significant changes or planned changes in the use of the assets. If an impairment review is performed to evaluate a long-lived asset for recoverability, the Company compares forecasts of undiscounted cash flows expected to result from the use and eventual disposition of the long-lived asset to its carrying value. An impairment loss would be recognized when estimated undiscounted future cash flows expected to result from the use of an asset are less than its carrying amount. The impairment loss would be based on the excess of the carrying value of the impaired asset over its fair value, determined based on discounted cash flows. To date, the Company has not recorded any impairment losses on long-lived assets.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Research and Development Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Research and development costs are expensed as incurred. Included in research and development expenses are wages, stock-based compensation and benefits of employees, third-party license fees and milestones and other operational costs related to the Company’s research and development activities, including facility-related expenses and external costs of outside vendors engaged to conduct both pre-clinical studies and clinical trials. The Company records research and development expenses net of any research and development tax incentives the Company is entitled to receive from government authorities.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Research Contract Costs and Accruals</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company has entered into various research and development contracts with research institutions and other companies both inside and outside of the United States. These agreements are generally cancelable, and related payments are recorded as research and development expenses as incurred. The Company records accruals for estimated ongoing research costs. When evaluating the adequacy of the accrued liabilities, the Company analyzes progress of the studies, including the phase or completion of events, invoices received and contracted costs. Significant judgments and estimates are made in determining the accrued balances at the end of any reporting period. Actual results could differ from the Company’s estimates. The Company’s historical accrual estimates have not been materially different from the actual costs.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Patent Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> All patent-related costs incurred in connection with filing and prosecuting patent applications are recorded as general and administrative expenses as incurred, as recoverability of such expenditures is uncertain.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Accounting for Stock-Based Compensation</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company measures all stock options and other stock-based awards granted to employees and directors at the fair value on the date of the grant using the Black-Scholes option-pricing model. The fair value of the awards is recognized as expense, net of estimated forfeitures, over the requisite service period, which is generally the vesting period of the respective award. The straight-line method of expense recognition is applied to all awards with service-only conditions.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> For stock-based awards granted to consultants and nonemployees, compensation expense is recognized over the period during which services are rendered by such consultants and nonemployees until completed. At the end of each financial reporting period prior to completion of the service, the fair value of these awards is re-measured using the then-current fair value of the Company’s common stock and updated assumption inputs in the Black-Scholes option-pricing model.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 12pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company classifies stock-based compensation expense in its consolidated statement of operations and comprehensive loss in the same manner in which the award recipient’s payroll costs are classified or in which the award recipients’ service payments are classified.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company recognizes compensation expense for only the portion of awards that are expected to vest. In developing a forfeiture rate estimate, the Company has considered its historical experience to estimate pre-vesting forfeitures for service-based awards. The impact of a forfeiture rate adjustment will be recognized in full in the period of adjustment, and if the actual forfeiture rate is materially different from the Company’s estimate, the Company may be required to record adjustments to stock-based compensation expense in future periods.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Income Taxes</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company accounts for income taxes using the asset and liability method, which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been recognized in the consolidated financial statements or in the Company’s tax returns. Deferred taxes are determined based on the difference between the financial statement and tax basis of assets and liabilities using enacted tax rates in effect in the years in which the differences are expected to reverse. Changes in deferred tax assets and liabilities are recorded in the provision for income taxes. The Company assesses the likelihood that its deferred tax assets will be recovered from future taxable income and, to the extent it believes, based upon the weight of available evidence, that it is more likely than not that all or a portion of deferred tax assets will not be realized, a valuation allowance is established through a charge to income tax expense. Potential for recovery of deferred tax assets is evaluated by estimating the future taxable profits expected and considering prudent and feasible tax planning strategies.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company accounts for uncertainty in income taxes recognized in the consolidated financial statements by applying a two-step process to determine the amount of tax benefit to be recognized. First, the tax position must be evaluated to determine the likelihood that it will be sustained upon external examination by the taxing authorities. If the tax position is deemed more-likely-than-not to be sustained, the tax position is then assessed to determine the amount of benefit to recognize in the consolidated financial statements. The amount of the benefit that may be recognized is the largest amount that has a greater than 50% likelihood of being realized upon ultimate settlement. The provision for income taxes includes the effects of any resulting tax reserves, or unrecognized tax benefits, that are considered appropriate as well as the related net interest and penalties.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Segment Data</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company’s singular focus is on advancing novel therapeutics for patients suffering from severe obesity and obesity-related disorders. No revenue has been generated since inception, and all tangible assets are held in the United States.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Comprehensive Loss</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Comprehensive loss includes net loss as well as other changes in stockholders’ equity (deficit) that result from transactions and economic events other than those with stockholders. For the nine months ended September 30, 2014 and 2013, there was no difference between net loss and comprehensive loss.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 18pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Net Income (Loss) Per Share</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Upon the closing of the Company’s IPO in June 2014, all of the Company’s outstanding redeemable convertible preferred shares were converted into shares of common stock. Prior to this conversion, the Company followed the two-class method when computing net income (loss) per share as the Company had issued shares that meet the definition of participating securities. The two-class method determines net income (loss) per share for each class of common and participating securities according to dividends declared or accumulated and participation rights in undistributed earnings. The two-class method requires income available to common shareholders for the period to be allocated between common and participating securities based upon their respective rights to receive dividends as if all income for the period had been distributed. The Company’s redeemable convertible preferred shares contractually entitled the holders of such shares to participate in dividends, but did not contractually require the holders of such shares to participate in losses of the Company. Accordingly, the two-class method did not apply for periods in which the Company reported a net loss or a net loss attributable to common shareholders resulting from dividends or accretion related to its redeemable convertible preferred shares.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Basic net income (loss) per share attributable to common shareholders is computed by dividing the net income (loss) attributable to common shareholders by the weighted average number of common shares outstanding for the period. Diluted net income (loss) per share attributable to common shareholders is computed by dividing the diluted net income (loss) attributable to common shareholders by the weighted average number of common shares, including potential dilutive common shares assuming the dilutive effect of outstanding stock options and unvested restricted common shares, as determined using the treasury stock method. For periods in which the Company has reported net losses, diluted net loss per common share attributable to common shareholders is the same as basic net loss per common share attributable to common shareholders, since dilutive common shares are not assumed to have been issued if their effect is antidilutive.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company reported a net loss attributable to common stockholders for the nine months ended September 30, 2014 and 2013.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The following common stock equivalents, outstanding as of September 30, 2014 and 2013, were excluded from the computation of diluted net loss per share for the nine months ended September 30, 2014 and 2013 because they had an anti-dilutive impact:</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 12pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="92%" align="center" border="0"> <tr> <td width="75%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: 'Times New Roman'"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="6" align="center"><b>As of September 30,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: 'Times New Roman'"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2014</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 1pt"> <td height="8"></td> <td height="8" colspan="4"></td> <td height="8" colspan="4"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Options to purchase common stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,839,895</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,283,264</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">78,372,931</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Total options and redeemable convertible preferred stock exercisable or convertible into common stock</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,839,895</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">79,656,195</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Recently Issued and Adopted Accounting Pronouncements</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In June 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2014-10, <i>Development Stage Entities</i>. The amendments in this guidance remove all incremental financial reporting requirements for development stage entities. Among other changes, this guidance will no longer require development stage entities to present inception-to-date information about income statement line items, cash flows, and equity transactions. This guidance is effective for public companies in the first annual period beginning after December 15, 2014. Early application is permitted for interim and annual periods for which financial statements have not yet been issued. The Company early adopted this guidance in the three months ended June 30, 2014 and, as a result, no longer discloses inception-to-date information in its consolidated statements of operations and comprehensive loss, cash flows and stockholders’ deficit and the related notes thereto.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In August 2014, the FASB issued ASU No. 2014-15, <i>Presentation of Financial Statements — Going Concern</i>. The new guidance addresses management’s responsibility to evaluate whether there is substantial doubt about an entity’s ability to continue as a going concern and to provide related footnote disclosures. Management’s evaluation should be based on relevant conditions and events that are known and reasonably knowable at the date that the financial statements are issued. The standard will be effective for the first interim period within annual reporting periods beginning after December 15, 2016. Early adoption is permitted. The Company is evaluating the effect that this guidance will have on its consolidated financial statements.</p> </div> </us-gaap:SignificantAccountingPoliciesTextBlock> | |||||||||||||||||||||
| <dei:EntityCentralIndexKey contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_2C18E821-2E88-4AC1-AB9B-DF854F9E6FC7_1_2"> 0001374690 </dei:EntityCentralIndexKey> | |||||||||||||||||||||
| <us-gaap:DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_E8F1D250-79AA-4360-8500-843072FDEBE9_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>6. Stock-Based Awards</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt"> <b>Stock Option Plans</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company’s Amended and Restated 2006 Stock Option Plan (the “2006 Plan”) provided for the Company to sell or issue common stock or restricted common stock, or to grant incentive stock options or nonqualified stock options for the purchase of common stock, to employees, members of the board of directors and consultants of the Company. The 2006 Plan is administered by the board of directors, or at the discretion of the board of directors, by a committee of the board. The exercise prices, vesting and other restrictions are determined at the discretion of the board of directors, or a committee of the board of directors if so delegated, except that the exercise price per share of stock options may not be less than 100% of the fair market value of the share of common stock on the date of grant and the term of stock option may not be greater than ten years. The total number of shares of common stock that could be issued under the 2006 Plan was 1,889,150 shares. Upon closing of the Company’s IPO, 168,221 shares reserved and not then subject to outstanding options were transferred to the 2014 Stock Option and Incentive Plan, and no further awards will be made under the 2006 Plan.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> On June 5, 2014, the Company’s stockholders approved the 2014 Stock Option and Incentive Plan (the “2014 Stock Option Plan”), which became effective upon the completion of the IPO of the Company’s shares of common stock in June 2014. The 2014 Stock Option Plan provides for the grant of stock options, stock appreciation rights, restricted stock, restricted stock units, unrestricted stock, performance-share awards and cash-based awards. The number of shares initially reserved for issuance under the 2014 Stock Option Plan is 2,168,221 shares of common stock and may be increased by the number of shares under the 2006 Plan that are not needed to fulfill the Company’s obligations for awards issued under the 2006 Plan as a result of forfeiture, expiration, cancellation, termination or net issuances of awards thereunder. The number of shares of common stock that may be issued under the plan is also subject to increase on the first day of each fiscal year by the lesser of (i) 4% of the Company’s outstanding shares of common stock as of that date, or (ii) an amount determined by the board of directors.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company generally grants stock-based awards with service conditions only (“service-based” awards).</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As required by the 2006 Plan and 2014 Stock Option Plan, the exercise price for stock options granted is not to be less than the fair value of common shares as of the date of grant. Prior to the IPO, the value of common stock was determined by the board of directors by taking into consideration its most recently available valuation of common shares performed by management and the board of directors as well as additional factors which might have changed since the date of the most recent contemporaneous valuation through the date of grant.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> During the nine months ended September 30, 2014, the Company granted stock options for the purchase of 529,565 shares of common stock, of which options for the purchase of 527,973 shares were granted to employees and options for the purchase of 1,592 shares were granted to a consultant.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>2014 Employee Stock Purchase Plan</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> On June 5, 2014, the Company’s stockholders approved the 2014 Employee Stock Purchase Plan. A total of 265,000 shares of common stock were reserved for issuance under this plan. The 2014 Employee Stock Purchase Plan became effective upon the completion of the IPO of the Company’s shares of common stock. The first offering period commenced on September 1, 2014. The per share purchase price for offerings is equal to the lesser of 85% of the closing market price of the Company’s common stock on the first day or last day of the offering period. As of September 30, 2014, there are 265,000 shares of common stock available for issuance to participating employees under the plan.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Stock Option Valuation</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The fair value of each stock option grant is estimated on the date of grant using the Black-Scholes option-pricing model. The Company historically has been a private company and lacks company-specific historical and implied volatility information. Therefore, it estimates its expected stock volatility based on the historical volatility of a publicly traded set of peer companies and expects to continue to do so until such time as it has adequate historical data regarding the volatility of its own traded stock price. The expected term of the Company’s stock options has been determined utilizing the “simplified” method for awards that qualify as “plain-vanilla” options. The expected term of stock options granted to nonemployees is equal to the contractual term of the option award. The risk-free interest rate is determined by reference to the U.S. Treasury yield curve in effect at the time of grant of the award for time periods approximately equal to the expected term of the award. Expected dividend yield is based on the fact that the Company has never paid cash dividends and does not expect to pay any cash dividends in the foreseeable future.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of September 30, 2014, there were outstanding unvested service-based stock options held by nonemployees for the purchase of 17,513 shares of common stock. Additionally as of September 30, 2014, there were outstanding unvested performance-based stock options held by nonemployees for the purchase of 796 shares of common stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 18pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>Stock-based Compensation</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company recorded stock-based compensation expense related to stock options and restricted common stock in the following expense categories of its statements of operations:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="92%" align="center" border="0"> <tr> <td width="84%"></td> <td valign="bottom" width="5%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="5%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="6" align="center"> <b>Nine Months Ended</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"><b>September 30,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2014</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Research and development</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">259</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">109</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> General and administrative</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">651</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">143</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">910</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">252</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of September 30, 2014, the Company had an aggregate of $6,224 of unrecognized stock-based compensation cost, which is expected to be recognized over a weighted average period of 3.4 years.</p> </div> </us-gaap:DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock> | |||||||||||||||||||||
| <us-gaap:EarningsPerShareBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="2" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_14" unitRef="iso4217_USD_per_shares"> -2.97 </us-gaap:EarningsPerShareBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_5B1ADC2F-32A9-4BAA-B206-C1029AECC0FC_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Impairment of Long-Lived Assets</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Long-lived assets consist of property and equipment. Long-lived assets to be held and used are tested for recoverability whenever events or changes in business circumstances indicate that the carrying amount of the assets may not be fully recoverable. Factors that the Company considers in deciding when to perform an impairment review include significant underperformance of the business in relation to expectations, significant negative industry or economic trends, and significant changes or planned changes in the use of the assets. If an impairment review is performed to evaluate a long-lived asset for recoverability, the Company compares forecasts of undiscounted cash flows expected to result from the use and eventual disposition of the long-lived asset to its carrying value. An impairment loss would be recognized when estimated undiscounted future cash flows expected to result from the use of an asset are less than its carrying amount. The impairment loss would be based on the excess of the carrying value of the impaired asset over its fair value, determined based on discounted cash flows. To date, the Company has not recorded any impairment losses on long-lived assets.</p> </div> </us-gaap:ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityDescription contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_8AB314B5-00EB-4C79-9535-ACAF72670988_1_0"> The Company was obligated to make monthly, interest-only payments on any term loans funded under the Credit Facility until December 1, 2014 and, thereafter, to pay 36 consecutive, equal monthly installments of principal and interest from January 1, 2015 through December 1, 2017. As per the terms of the agreement, in June 2014, upon the completion of the Company’s IPO, the term of monthly, interest-only payments were extended until June 1, 2015. </us-gaap:LineOfCreditFacilityDescription> | |||||||||||||||||||||
| <us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_BB3B5124-141A-409B-AB23-A027C1FA2D9A_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Recently Issued and Adopted Accounting Pronouncements</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In June 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2014-10, <i>Development Stage Entities</i>. The amendments in this guidance remove all incremental financial reporting requirements for development stage entities. Among other changes, this guidance will no longer require development stage entities to present inception-to-date information about income statement line items, cash flows, and equity transactions. This guidance is effective for public companies in the first annual period beginning after December 15, 2014. Early application is permitted for interim and annual periods for which financial statements have not yet been issued. The Company early adopted this guidance in the three months ended June 30, 2014 and, as a result, no longer discloses inception-to-date information in its consolidated statements of operations and comprehensive loss, cash flows and stockholders’ deficit and the related notes thereto.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In August 2014, the FASB issued ASU No. 2014-15, <i>Presentation of Financial Statements — Going Concern</i>. The new guidance addresses management’s responsibility to evaluate whether there is substantial doubt about an entity’s ability to continue as a going concern and to provide related footnote disclosures. Management’s evaluation should be based on relevant conditions and events that are known and reasonably knowable at the date that the financial statements are issued. The standard will be effective for the first interim period within annual reporting periods beginning after December 15, 2016. Early adoption is permitted. The Company is evaluating the effect that this guidance will have on its consolidated financial statements.</p> </div> </us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:PensionAndOtherPostretirementBenefitsDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_3EDB675F-C9D7-44B2-854A-BC22B6E1BAA7_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>8. Retirement Plan</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company has a Savings Incentive Match Plan for employees. Under the terms of the plan, the Company contributes 2% of an employee’s annual base salary, up to a maximum of the annual Internal Revenue Service compensation limits, for all full-time employees. During the nine months ended September 30, 2014 and 2013, the Company recognized $43 and $20, respectively, of expense related to its contributions to the plan.</p> </div> </us-gaap:PensionAndOtherPostretirementBenefitsDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:SegmentReportingPolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_7E657AE9-412E-4E54-9FE5-B229FD764228_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Segment Data</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company’s singular focus is on advancing novel therapeutics for patients suffering from severe obesity and obesity-related disorders. No revenue has been generated since inception, and all tangible assets are held in the United States.</p> </div> </us-gaap:SegmentReportingPolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="INF" id="id_6893637_D4283396-64A3-4317-81E2-67698D5DC014_1_2" unitRef="shares"> 1839895 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:ConcentrationRiskCreditRisk contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_DB3F4764-9951-4EBB-BB06-9761B119E66C_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Concentration of Credit Risk and of Significant Suppliers</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Financial instruments that potentially expose the Company to concentrations of credit risk consist primarily of cash and cash equivalents. The Company has all cash and cash equivalents balances at one accredited financial institution, in amounts that exceed federally insured limits. The Company does not believe that it is subject to unusual credit risk beyond the normal credit risk associated with commercial banking relationships.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company is dependent on third-party manufacturers to supply products for research and development activities in its programs. In particular, the Company relies and expects to continue to rely on a small number of manufacturers to supply it with its requirements for the active pharmaceutical ingredients and formulated drugs related to these programs. These programs could be adversely affected by a significant interruption in the supply of active pharmaceutical ingredients and formulated drugs.</p> </div> </us-gaap:ConcentrationRiskCreditRisk> | |||||||||||||||||||||
| <us-gaap:FairValueMeasurementPolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_B0DC2F39-E860-41F0-A7DE-64A3BF363E21_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Fair Value Measurements</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Certain assets and liabilities are carried at fair value under GAAP. Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. Financial assets and liabilities carried at fair value are to be classified and disclosed in one of the following three levels of the fair value hierarchy, of which the first two are considered observable and the last is considered unobservable:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 6pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 1—Quoted prices in active markets for identical assets or liabilities.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 6pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 2—Observable inputs (other than Level 1 quoted prices) such as quoted prices in active markets for similar assets or liabilities, quoted prices in markets that are not active for identical or similar assets or liabilities, or other inputs that are observable or can be corroborated by observable market data.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 6pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 3—Unobservable inputs that are supported by little or no market activity and that are significant to determining the fair value of the assets or liabilities, including pricing models, discounted cash flow methodologies and similar techniques.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company’s cash equivalents of $100,000 and $26,501 as of September 30, 2014 and December 31, 2013, respectively, were carried at fair value based on quoted prices in active markets, a Level 1 measurement. The carrying values of accounts payable and accrued expenses approximate their fair value due to the short-term nature of these liabilities. The Company’s carrying value of outstanding debt issued in the first quarter of 2014 approximates fair value based on the recent execution date of the credit facility agreement, and is considered a Level 2 measurement.</p> </div> </us-gaap:FairValueMeasurementPolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationOptionAndIncentivePlansPolicy contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_A9100D4D-5005-4977-9298-D7E2DAC0A5C9_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Accounting for Stock-Based Compensation</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company measures all stock options and other stock-based awards granted to employees and directors at the fair value on the date of the grant using the Black-Scholes option-pricing model. The fair value of the awards is recognized as expense, net of estimated forfeitures, over the requisite service period, which is generally the vesting period of the respective award. The straight-line method of expense recognition is applied to all awards with service-only conditions.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> For stock-based awards granted to consultants and nonemployees, compensation expense is recognized over the period during which services are rendered by such consultants and nonemployees until completed. At the end of each financial reporting period prior to completion of the service, the fair value of these awards is re-measured using the then-current fair value of the Company’s common stock and updated assumption inputs in the Black-Scholes option-pricing model.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt; TEXT-INDENT: 4%"> The Company classifies stock-based compensation expense in its consolidated statement of operations and comprehensive loss in the same manner in which the award recipient’s payroll costs are classified or in which the award recipients’ service payments are classified.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company recognizes compensation expense for only the portion of awards that are expected to vest. In developing a forfeiture rate estimate, the Company has considered its historical experience to estimate pre-vesting forfeitures for service-based awards. The impact of a forfeiture rate adjustment will be recognized in full in the period of adjustment, and if the actual forfeiture rate is materially different from the Company’s estimate, the Company may be required to record adjustments to stock-based compensation expense in future periods.</p> </div> </us-gaap:ShareBasedCompensationOptionAndIncentivePlansPolicy> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_22" unitRef="iso4217_USD"> 2312000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossUnrealized contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_6" unitRef="iso4217_USD"> -31000 </us-gaap:ForeignCurrencyTransactionGainLossUnrealized> | |||||||||||||||||||||
| <us-gaap:PaymentsForDeposits contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_15" unitRef="iso4217_USD"> 57000 </us-gaap:PaymentsForDeposits> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_8" unitRef="iso4217_USD"> 997000 </us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets> | |||||||||||||||||||||
| <us-gaap:OperatingIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_5" unitRef="iso4217_USD"> -24868000 </us-gaap:OperatingIncomeLoss> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_9" unitRef="iso4217_USD"> -23000 </us-gaap:ForeignCurrencyTransactionGainLossBeforeTax> | |||||||||||||||||||||
| <us-gaap:NonoperatingIncomeExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_10" unitRef="iso4217_USD"> -679000 </us-gaap:NonoperatingIncomeExpense> | |||||||||||||||||||||
| <us-gaap:PaymentsOfDebtIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_20" unitRef="iso4217_USD"> 49000 </us-gaap:PaymentsOfDebtIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:Revenues contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_0" unitRef="iso4217_USD"> 0 </us-gaap:Revenues> | |||||||||||||||||||||
| <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_14" unitRef="iso4217_USD"> 42000 </us-gaap:PaymentsToAcquirePropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_13" unitRef="iso4217_USD"> -25639000 </us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_11" unitRef="iso4217_USD"> -25547000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:InvestmentIncomeInterest contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_7" unitRef="iso4217_USD"> 2000 </us-gaap:InvestmentIncomeInterest> | |||||||||||||||||||||
| <us-gaap:InterestPaid contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_32" unitRef="iso4217_USD"> 480000 </us-gaap:InterestPaid> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInIncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_9" unitRef="iso4217_USD"> -368000 </us-gaap:IncreaseDecreaseInIncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_3" unitRef="iso4217_USD"> 910000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:InterestExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_8" unitRef="iso4217_USD"> 658000 </us-gaap:InterestExpense> | |||||||||||||||||||||
| <us-gaap:OperatingExpenses contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_4" unitRef="iso4217_USD"> 24868000 </us-gaap:OperatingExpenses> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_2" unitRef="iso4217_USD"> 20046000 </us-gaap:ResearchAndDevelopmentExpense> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_24" unitRef="iso4217_USD"> 91513000 </us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease> | |||||||||||||||||||||
| <us-gaap:ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="INF" id="id_6893637_F03C66A2-A7CC-4881-A283-37FF5A92C584_1_0" unitRef="iso4217_USD"> 0 </us-gaap:ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesRentExpenseNet contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_44DABFB7-3E71-4DE6-8DE2-65A0A52DDB4A_1_0" unitRef="iso4217_USD"> 104000 </us-gaap:OperatingLeasesRentExpenseNet> | |||||||||||||||||||||
| <us-gaap:ProceedsFromNotesPayable contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_19" unitRef="iso4217_USD"> 7386000 </us-gaap:ProceedsFromNotesPayable> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_12" unitRef="iso4217_USD"> 92000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:Depreciation contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_5" unitRef="iso4217_USD"> 10000 </us-gaap:Depreciation> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_23" unitRef="iso4217_USD"> 108139000 </us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_18" unitRef="iso4217_USD"> 442000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:ConversionOfStockAmountConverted1 contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_30" unitRef="iso4217_USD"> 104331000 </us-gaap:ConversionOfStockAmountConverted1> | |||||||||||||||||||||
| <us-gaap:DefinedContributionPlanCostRecognized contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_90DADE2D-AAAF-4C98-844A-19931FE92F21_1_0" unitRef="iso4217_USD"> 43000 </us-gaap:DefinedContributionPlanCostRecognized> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccruedLiabilities contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_11" unitRef="iso4217_USD"> 9078000 </us-gaap:IncreaseDecreaseInAccruedLiabilities> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_16" unitRef="iso4217_USD"> -99000 </us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:PaidInKindInterest contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_4" unitRef="iso4217_USD"> 36000 </us-gaap:PaidInKindInterest> | |||||||||||||||||||||
| <us-gaap:GeneralAndAdministrativeExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_CF481CBA-1BA0-4B63-AD63-6F43382443E2_1_3" unitRef="iso4217_USD"> 4822000 </us-gaap:GeneralAndAdministrativeExpense> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccountsPayable contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_10" unitRef="iso4217_USD"> -416000 </us-gaap:IncreaseDecreaseInAccountsPayable> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceInitialPublicOffering contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_DE03031F-8391-496C-9C4F-653D24E4DF03_1_21" unitRef="iso4217_USD"> 102672000 </us-gaap:ProceedsFromIssuanceInitialPublicOffering> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityPeriodicPaymentInterest contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="-3" id="id_6893637_4CE801B9-1EA5-4E64-88B1-F84D711F9F18_1_0" unitRef="iso4217_USD"> 658000 </us-gaap:LineOfCreditFacilityPeriodicPaymentInterest> | |||||||||||||||||||||
| <zfgn:EffectiveIncomeTaxRateReconciliationTaxRefundsRelatedToResearchAndDevelopment contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="2" id="id_6893637_8082329D-A39F-4C01-A4E0-D1C0A8E083AC_1_0" unitRef="pure"> 0.45 </zfgn:EffectiveIncomeTaxRateReconciliationTaxRefundsRelatedToResearchAndDevelopment> | |||||||||||||||||||||
| <zfgn:LikelihoodPercentageMinimum contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="INF" id="id_6893637_CAF7CA3D-47B4-47D8-B567-0E8C873C9780_1_0" unitRef="pure"> 0.50 </zfgn:LikelihoodPercentageMinimum> | |||||||||||||||||||||
| <zfgn:FinancialCovenantsUnderCreditFacility contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" decimals="INF" id="id_6893637_94BAB2CF-33F8-4FCA-AD7D-63FDA4DA261A_1_1" unitRef="iso4217_USD"> 0 </zfgn:FinancialCovenantsUnderCreditFacility> | |||||||||||||||||||||
| <zfgn:ShortTermInvestmentMaturityPeriodDescription contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_99474C31-BC7A-4296-BE93-15C7E9DC2C76_1_0"> Ninety days or less </zfgn:ShortTermInvestmentMaturityPeriodDescription> | |||||||||||||||||||||
| <zfgn:UnauditedInterimFinancialInformationPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_3EB54990-6F6C-4B45-A3D6-60BC7EE04F85_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Unaudited Interim Financial Information</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The consolidated balance sheet at December 31, 2013 was derived from audited financial statements, but does not include all disclosures required by GAAP. The accompanying unaudited consolidated financial statements as of September 30, 2014, and for the nine months ended September 30, 2014 and 2013, have been prepared by the Company, pursuant to the rules and regulations of the SEC for interim financial statements. Certain information and footnote disclosures normally included in financial statements prepared in accordance with GAAP have been condensed or omitted pursuant to such rules and regulations. However, the Company believes that the disclosures are adequate to make the information presented not misleading. These consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements and the notes thereto for the year ended December 31, 2013. In the opinion of management, all adjustments, consisting only of normal recurring adjustments necessary for a fair statement of the Company’s consolidated financial position as of September 30, 2014 and consolidated results of operations and consolidated cash flows for the nine months ended September 30, 2014 and 2013 have been made. The results for the nine months ended September 30, 2014 are not necessarily indicative of the results that may be expected for the year ending December 31, 2014, any other interim periods, or any future year or period.</p> </div> </zfgn:UnauditedInterimFinancialInformationPolicyTextBlock> | |||||||||||||||||||||
| <zfgn:ResearchContractCostsAndAccrualsPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0" id="id_6893637_77F2C156-C246-471A-80AF-F122A05FDBD2_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Research Contract Costs and Accruals</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company has entered into various research and development contracts with research institutions and other companies both inside and outside of the United States. These agreements are generally cancelable, and related payments are recorded as research and development expenses as incurred. The Company records accruals for estimated ongoing research costs. When evaluating the adequacy of the accrued liabilities, the Company analyzes progress of the studies, including the phase or completion of events, invoices received and contracted costs. Significant judgments and estimates are made in determining the accrued balances at the end of any reporting period. Actual results could differ from the Company’s estimates. The Company’s historical accrual estimates have not been materially different from the actual costs.</p> </div> </zfgn:ResearchContractCostsAndAccrualsPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1268687x1281225" decimals="INF" id="id_6893637_D4283396-64A3-4317-81E2-67698D5DC014_2001_0" unitRef="shares"> 1839895 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1 contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1269523x1275948_1280964x1382801" id="id_6893637_F2F7AF9F-55B8-4319-AF07-D36C3EAEAAE5_1001_3"> P10Y </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1270313x1275629" decimals="INF" id="id_6893637_144BE4DD-A4A3-4531-9D4D-2EE4A427DD0E_1001_1" unitRef="shares"> 527973 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1270313x1494998" decimals="INF" id="id_6893637_144BE4DD-A4A3-4531-9D4D-2EE4A427DD0E_2001_2" unitRef="shares"> 1592 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross> | |||||||||||||||||||||
| <zfgn:PercentageReductionResearchAndDevelopmentCosts contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1273333x1281276" decimals="2" id="id_6893637_080DC78D-2B7B-4552-BD83-9A59C11CC1B4_1001_2" unitRef="pure"> 0.45 </zfgn:PercentageReductionResearchAndDevelopmentCosts> | |||||||||||||||||||||
| <us-gaap:StockholdersEquityNoteStockSplitConversionRatio1 contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1273334x1272538_1276401x1270422" decimals="4" id="id_6893637_58DC5AEC-40FF-40A1-9606-36DCCDE04E02_1001_1" unitRef="pure"> 0.1592 </us-gaap:StockholdersEquityNoteStockSplitConversionRatio1> | |||||||||||||||||||||
| <us-gaap:LeaseExpirationDate1 contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1273383x1591562" id="id_6893637_1F11D39F-569C-4418-B621-01C605579C88_1001_0"> 2017-07-31 </us-gaap:LeaseExpirationDate1> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1274159x1269133" decimals="-3" id="id_6893637_D33320FF-60EB-4BEC-8834-BE1EE799939E_1001_1" unitRef="iso4217_USD"> 651000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1274159x1269570" decimals="-3" id="id_6893637_D33320FF-60EB-4BEC-8834-BE1EE799939E_2001_0" unitRef="iso4217_USD"> 259000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityInitiationDate1 contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760" id="id_6893637_71DB2F59-4CA7-475A-952B-5EF3906DBF5D_1001_0"> 2014-03-31 </us-gaap:LineOfCreditFacilityInitiationDate1> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityExpirationDate1 contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760" id="id_6893637_78075A1B-2D67-46BD-BBA6-4D60D4C3EAC9_1001_0"> 2017-12-01 </us-gaap:LineOfCreditFacilityExpirationDate1> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityInterestRateDuringPeriod contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760" decimals="3" id="id_6893637_5AF9FE39-825C-4C45-8E84-C638D056F72A_1001_0" unitRef="pure"> 0.081 </us-gaap:LineOfCreditFacilityInterestRateDuringPeriod> | |||||||||||||||||||||
| <us-gaap:LineOfCreditFacilityDescription contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760" id="id_6893637_78075A1B-2D67-46BD-BBA6-4D60D4C3EAC9_1001_1"> On March 31, 2014, the Company received proceeds of $7,500 from the issuance of promissory notes under the Term Loan A. Of the additional $12,500 amount that is available, $7,500 (“Term Loan B”) was available to be drawn down until September 30, 2014 and $5,000 (“Term Loan C”) was available to be drawn down for a 30-day period upon the completion of the Company’s IPO that occurred in June 2014. The Company elected not to draw down Term Loans B or C and these amounts are no longer available to the Company. All promissory notes issued under the Credit Facility are collateralized by substantially all of the Company’s personal property, other than its intellectual property. </us-gaap:LineOfCreditFacilityDescription> | |||||||||||||||||||||
| <zfgn:AdditionalInterestExpenseForInitialPublicOffering contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760" decimals="-3" id="id_6893637_94BAB2CF-33F8-4FCA-AD7D-63FDA4DA261A_1001_0" unitRef="iso4217_USD"> 225000 </zfgn:AdditionalInterestExpenseForInitialPublicOffering> | |||||||||||||||||||||
| <zfgn:LineOfCreditFacilityAdditionalFeePercentage contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760" decimals="3" id="id_6893637_5AF9FE39-825C-4C45-8E84-C638D056F72A_1001_1" unitRef="pure"> 0.060 </zfgn:LineOfCreditFacilityAdditionalFeePercentage> | |||||||||||||||||||||
| <us-gaap:DebtInstrumentIncreaseAccruedInterest contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760_1280323x1450314" decimals="-3" id="id_6893637_5AF9FE39-825C-4C45-8E84-C638D056F72A_2001_2" unitRef="iso4217_USD"> 450000 </us-gaap:DebtInstrumentIncreaseAccruedInterest> | |||||||||||||||||||||
| <us-gaap:InterestExpense contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760_1280323x1450314_1280806x1591559" decimals="-3" id="id_6893637_2063124B-025E-46F9-A7B3-11669E59C004_2002_2" unitRef="iso4217_USD"> 36000 </us-gaap:InterestExpense> | |||||||||||||||||||||
| <us-gaap:StockholdersEquityReverseStockSplit contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1276401x1270422" id="id_6893637_58DC5AEC-40FF-40A1-9606-36DCCDE04E02_2001_0"> Company effected a 1-for-6.28 reverse stock split of its issued and outstanding shares of common stock and a proportional adjustment to the existing conversion ratios for each series of redeemable convertible preferred stock. </us-gaap:StockholdersEquityReverseStockSplit> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1276401x1270422" decimals="INF" id="id_6893637_144BE4DD-A4A3-4531-9D4D-2EE4A427DD0E_3001_0" unitRef="shares"> 529565 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossUnrealized contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1280651x1574427" decimals="-3" id="id_6893637_080DC78D-2B7B-4552-BD83-9A59C11CC1B4_2001_0" unitRef="iso4217_USD"> -31000 </us-gaap:ForeignCurrencyTransactionGainLossUnrealized> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1280964x1371249" decimals="INF" id="id_6893637_E3F53C9E-947E-4884-B13D-CB92B9126DCC_1001_1" unitRef="pure"> 0.04 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent contextRef="eol_PE720058--14S-1-0007_STD_273_20140930_0_1280964x1382801" decimals="INF" id="id_6893637_F2F7AF9F-55B8-4319-AF07-D36C3EAEAAE5_2001_0" unitRef="pure"> 1.00 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_28_20140228_0_1271378x1273350_1276400x1271310" decimals="-3" id="id_6893637_38319CCC-3808-40F3-A256-18A9F1195CCE_1001_3" unitRef="iso4217_USD"> 1000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_28_20140228_0_1271378x1273350_1276400x1271310" decimals="-3" id="id_6893637_38319CCC-3808-40F3-A256-18A9F1195CCE_1001_2" unitRef="iso4217_USD"> 443000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_29_20120229_0_1276400x1279561" decimals="-3" id="id_6893637_E47E22D1-629E-4D7D-9DE5-E3D1DF7A4B57_1001_3" unitRef="iso4217_USD"> 8000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_29_20120229_0_1276400x1279561" decimals="-3" id="id_6893637_E47E22D1-629E-4D7D-9DE5-E3D1DF7A4B57_1001_2" unitRef="iso4217_USD"> 7075000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:DebtConversionConvertedInstrumentSharesIssued1 contextRef="eol_PE720058--14S-1-0007_STD_30_20121130_0_1276400x1281158" decimals="INF" id="id_6893637_774955CB-9842-4BE3-917D-4AC1714BA884_2002_7" unitRef="shares"> 4975260 </us-gaap:DebtConversionConvertedInstrumentSharesIssued1> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_30_20121130_0_1276400x1281158" decimals="-3" id="id_6893637_2C3062AE-B539-41CF-898C-BD8363521D60_1001_3" unitRef="iso4217_USD"> 54000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:DebtConversionConvertedInstrumentAmount1 contextRef="eol_PE720058--14S-1-0007_STD_30_20121130_0_1276400x1281158" decimals="-3" id="id_6893637_774955CB-9842-4BE3-917D-4AC1714BA884_2002_6" unitRef="iso4217_USD"> 6086000 </us-gaap:DebtConversionConvertedInstrumentAmount1> | |||||||||||||||||||||
| <us-gaap:DebtInstrumentIncreaseAccruedInterest contextRef="eol_PE720058--14S-1-0007_STD_30_20121130_0_1276400x1281158" decimals="-3" id="id_6893637_2C3062AE-B539-41CF-898C-BD8363521D60_1001_5" unitRef="iso4217_USD"> 86000 </us-gaap:DebtInstrumentIncreaseAccruedInterest> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_30_20121130_0_1276400x1281158" decimals="-3" id="id_6893637_774955CB-9842-4BE3-917D-4AC1714BA884_2002_5" unitRef="iso4217_USD"> 9044000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_30_20131130_0_1276400x1271310" decimals="-3" id="id_6893637_EA628405-1521-42BD-988D-BDB5A13C06B0_1001_3" unitRef="iso4217_USD"> 156000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_30_20131130_0_1276400x1271310" decimals="-3" id="id_6893637_EA628405-1521-42BD-988D-BDB5A13C06B0_1001_2" unitRef="iso4217_USD"> 35000000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_31_20130131_0_1276400x1281158" decimals="-3" id="id_6893637_1C7B76AD-B215-40A1-9C83-4DE37B0EF604_1001_3" unitRef="iso4217_USD"> 1000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_31_20130131_0_1276400x1281158" decimals="-3" id="id_6893637_1C7B76AD-B215-40A1-9C83-4DE37B0EF604_1001_2" unitRef="iso4217_USD"> 5956000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="eol_PE720058--14S-1-0007_STD_365_20101231_0" id="id_6893637_B27D47F3-E181-4656-870C-C8832CFB79CA_1001_2"> P8Y6M </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_4001_3" unitRef="shares"> 475793 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="2" id="id_6893637_780167DC-C6E5-48FF-BF9F-B248C8D82D10_1_0" unitRef="iso4217_USD_per_shares"> 1.07 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_1_8" unitRef="pure"> 0.000 </us-gaap:EffectiveIncomeTaxRateContinuingOperations> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_13" unitRef="iso4217_USD"> -12274000 </us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="2" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_1_3" unitRef="pure"> 0.00 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1 contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_1_1"> P6Y3M </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_1_3" unitRef="pure"> -0.054 </us-gaap:EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="4" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_1_0" unitRef="pure"> 0.0141 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate> | |||||||||||||||||||||
| <us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="0" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_14" unitRef="shares"> 688946 </us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_1_7" unitRef="pure"> 0.455 </us-gaap:EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" id="id_6893637_B27D47F3-E181-4656-870C-C8832CFB79CA_2001_3"> P8Y8M12D </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_4001_3" unitRef="iso4217_USD_per_shares"> 1.57 </us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:EarningsPerShareBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="2" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_13" unitRef="iso4217_USD_per_shares"> -19.17 </us-gaap:EarningsPerShareBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_1_0" unitRef="pure"> -0.340 </us-gaap:EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationTaxCreditsResearch contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_1_1" unitRef="pure"> -0.064 </us-gaap:EffectiveIncomeTaxRateReconciliationTaxCreditsResearch> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="2" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_1_2" unitRef="pure"> 0.78 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_1_2" unitRef="shares"> 940642 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseMealsAndEntertainment contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_1_4" unitRef="pure"> 0.001 </us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseMealsAndEntertainment> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_1_5" unitRef="pure"> 0.002 </us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost> | |||||||||||||||||||||
| <us-gaap:PaymentsForDeposits contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_17" unitRef="iso4217_USD"> 12000 </us-gaap:PaymentsForDeposits> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_9" unitRef="iso4217_USD"> 61000 </us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets> | |||||||||||||||||||||
| <us-gaap:GainLossOnSaleOfPropertyPlantEquipment contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_7" unitRef="iso4217_USD"> 2000 </us-gaap:GainLossOnSaleOfPropertyPlantEquipment> | |||||||||||||||||||||
| <us-gaap:OperatingIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_5" unitRef="iso4217_USD"> -13154000 </us-gaap:OperatingIncomeLoss> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_8" unitRef="iso4217_USD"> -3000 </us-gaap:ForeignCurrencyTransactionGainLossBeforeTax> | |||||||||||||||||||||
| <us-gaap:NonoperatingIncomeExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_9" unitRef="iso4217_USD"> -3000 </us-gaap:NonoperatingIncomeExpense> | |||||||||||||||||||||
| <us-gaap:Revenues contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_0" unitRef="iso4217_USD"> 0 </us-gaap:Revenues> | |||||||||||||||||||||
| <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_15" unitRef="iso4217_USD"> 35000 </us-gaap:PaymentsToAcquirePropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_12" unitRef="iso4217_USD"> -13210000 </us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_10" unitRef="iso4217_USD"> -13157000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_4007_1000011" unitRef="iso4217_USD"> 80000 </us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_3" unitRef="iso4217_USD"> 80000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:OperatingExpenses contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_4" unitRef="iso4217_USD"> 13154000 </us-gaap:OperatingExpenses> | |||||||||||||||||||||
| <us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_F500908E-8A1D-406E-82BE-7F42055522F6_3_0" unitRef="iso4217_USD"> 18000 </us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_2" unitRef="iso4217_USD"> 11403000 </us-gaap:ResearchAndDevelopmentExpense> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_25" unitRef="iso4217_USD"> -2250000 </us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease> | |||||||||||||||||||||
| <us-gaap:CostOfServicesLicensesAndMaintenanceAgreements contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5682BFB1-C190-4F15-AA03-07ABAFB9AC0A_1_0" unitRef="iso4217_USD"> 1055000 </us-gaap:CostOfServicesLicensesAndMaintenanceAgreements> | |||||||||||||||||||||
| <us-gaap:IncomeTaxExpenseBenefit contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_E830BF17-5AE9-4E3E-8EDD-EECE710B648C_1_0" unitRef="iso4217_USD"> 0 </us-gaap:IncomeTaxExpenseBenefit> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesRentExpenseNet contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_974B82A8-83E7-4F80-B0D9-075E5FA84203_1_1" unitRef="iso4217_USD"> 102000 </us-gaap:OperatingLeasesRentExpenseNet> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_1_11" unitRef="iso4217_USD"> 53000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:Depreciation contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_5" unitRef="iso4217_USD"> 4000 </us-gaap:Depreciation> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_24" unitRef="iso4217_USD"> 10069000 </us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_20" unitRef="iso4217_USD"> 10069000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:ProceedsFromSaleOfPropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_16" unitRef="iso4217_USD"> 2000 </us-gaap:ProceedsFromSaleOfPropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:DefinedContributionPlanCostRecognized contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_C7F4924D-11EF-4C1E-8378-077C0A46092A_1_0" unitRef="iso4217_USD"> 15000 </us-gaap:DefinedContributionPlanCostRecognized> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccruedLiabilities contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_12" unitRef="iso4217_USD"> 905000 </us-gaap:IncreaseDecreaseInAccruedLiabilities> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_1_18" unitRef="iso4217_USD"> -45000 </us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations> | |||||||||||||||||||||
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| <zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountDecrease contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_1_1" unitRef="iso4217_USD"> 0 </zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountDecrease> | |||||||||||||||||||||
| <zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountIncrease contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_1_2" unitRef="iso4217_USD"> 5996000 </zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountIncrease> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1268687x1281225" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_1001_0" unitRef="shares"> 916094 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1268687x1487477" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_2001_1" unitRef="shares"> 24548 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1270313x1271210" decimals="0" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_4001_2" unitRef="iso4217_USD_per_shares"> 0 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_4001_3" unitRef="shares"> 13933 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_4001_2" unitRef="shares"> 0 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1270313x1271210" decimals="2" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_4001_3" unitRef="iso4217_USD_per_shares"> 0.75 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1270313x1271210" decimals="-3" id="id_6893637_AFC756F7-662B-4340-BD86-CFE20DAC72C3_1001_0" unitRef="iso4217_USD"> 22000 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1274159x1269133" decimals="-3" id="id_6893637_7C9FE533-0621-4211-BBE5-4EDB4B3FA109_1001_1" unitRef="iso4217_USD"> 50000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1274159x1269570" decimals="-3" id="id_6893637_7C9FE533-0621-4211-BBE5-4EDB4B3FA109_2001_0" unitRef="iso4217_USD"> 30000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1279561" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_5007_1000010" unitRef="iso4217_USD"> 33000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1279561" decimals="-3" id="id_6893637_55CF9383-B0C7-4F00-BD93-5C30212E59B5_1001_2" unitRef="iso4217_USD"> 8086000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1279561_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_5001_400009" unitRef="shares"> 8923884 </us-gaap:StockIssuedDuringPeriodSharesNewIssues> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1279561_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_5001_500008" unitRef="iso4217_USD"> 8053000 </us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1281157" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_6007_1000007" unitRef="iso4217_USD"> 9000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1281157_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_6001_400006" unitRef="shares"> 2682011 </us-gaap:StockIssuedDuringPeriodSharesNewIssues> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1281157_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_6001_500005" unitRef="iso4217_USD"> 2016000 </us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276401x1269588" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_4006_900013" unitRef="iso4217_USD"> -13157000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_4005_800011" unitRef="iso4217_USD"> 80000 </us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_4005_800012" unitRef="iso4217_USD"> 53000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_4001_500012" unitRef="iso4217_USD"> -53000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_897AD823-0937-43FD-A7E7-EABA383661FA_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>4. Accrued Expenses</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Accrued expenses consisted of the following as of December 31, 2012 and 2013:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="87%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued payroll and related expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">74</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">49</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued research and development expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,558</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">616</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued professional fees</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">62</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">196</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Accrued other</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">39</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1,699</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">900</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:CommitmentsAndContingenciesDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_19B08CA9-BCBE-4B3F-8B4B-7D938FCF39CA_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>10. Commitments and Contingencies</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt"> <b>Leases</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company leases its office space under an operating lease agreement that initially expired on July 31, 2013, but was amended in 2013 to extend the lease through January 31, 2014. The lease, as amended, allows for up to two six-month extension periods. In December 2013, the Company extended the lease through July 31, 2014, cancellable with 30 days’ notice.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Future minimum lease payments for its operating lease as of December 31, 2013 were as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="95%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom" nowrap="nowrap"> <p style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-BOTTOM: #000000 1pt solid; WIDTH: 92.45pt"> <b>Year Ending December 31,</b></p> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2014</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">64</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Total</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">64</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company also leased laboratory space in prior years; however, these leases terminated prior to 2011 and, as of December 31, 2013, there are no future commitments for laboratory space. During the years ended December 31, 2011, 2012 and 2013, the Company recognized $102, $129 and $<u>105</u>, respectively, of rental expense related to office space.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Intellectual Property Licenses</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company has acquired exclusive rights to develop patented compounds and related know-how for beloranib under two licensing agreements with two third parties in the course of its research and development activities. The licensing rights obligate the Company to make payments to the licensors for license fees, milestones, license maintenance fees and royalties. The Company is also responsible for patent prosecution costs. Related to these license agreements, the Company made payments and recorded research and development expenses in its consolidated statements of operations as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="78%"></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="10" align="center"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Licensing, milestone and license maintenance fees</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">1,055</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">150</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company is obligated to make additional milestone payments of up to $18,950 upon reaching certain pre-commercialization milestones, such as clinical trials and government approvals, and up to $12,500 upon reaching certain product commercialization milestones. Under one of the license agreements, the Company is also obligated to pay up to $1,250 with respect to each subsequent licensed product, if any, that is a new chemical entity. In addition, the Company will owe single-digit royalties on sales of commercial products developed using these licensed technologies, if any. The Company is also obligated to pay to the licensors a percentage of fees received if and when the Company sublicenses the technology. As of December 31, 2013, the Company has not yet developed a commercial product using the licensed technologies and it has not entered into any sublicense agreements for the technologies.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Indemnification Agreements</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> In the ordinary course of business, the Company may provide indemnification of varying scope and terms to vendors, lessors, business partners, and other parties with respect to certain matters including, but not limited to, losses arising out of breach of such agreements or from intellectual property infringement claims made by third parties. In addition, the Company has entered into indemnification agreements with members of its board of directors that will require the Company, among other things, to indemnify them against certain liabilities that may arise by reason of their status or service as directors or officers. The maximum potential amount of future payments the Company could be required to make under these indemnification agreements is, in many cases, unlimited. To date, the Company has not incurred any material costs as a result of such indemnifications. The Company does not believe that the outcome of any claims under indemnification arrangements will have a material effect on its financial position, results of operations or cash flows, and it has not accrued any liabilities related to such obligations in its consolidated financial statements as of December 31, 2012 or 2013.</p> </div> </us-gaap:CommitmentsAndContingenciesDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:DebtDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_544D919D-D96B-4858-99E5-459388DA10CC_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>5. Convertible Promissory Notes</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> In August and November 2012, the Company issued convertible promissory notes with a principal amount of $6,000. The notes accrued interest at an annual rate of 8% and, unless otherwise converted, were due one year from the issuance date. The notes were to be automatically converted into shares of a new class of preferred stock upon the sale by the Company of the new class of preferred stock yielding proceeds of at least $10,000 or, if the sale of the new class of preferred stock was for less than $10,000, the notes could be converted at the option of the noteholder at 90% of the price of the new series of preferred stock. In November 2012, upon the Company’s issuance of 6,653,988 shares of Series D redeemable convertible preferred stock for gross proceeds of $9,044 (see Note 6), the noteholders elected to convert the outstanding principal and accrued interest of $6,086 into 4,975,260 shares of Series D redeemable convertible preferred stock.</p> </div> </us-gaap:DebtDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:EarningsPerSharePolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_F369992C-6A5B-438F-A1C1-7F93A7AB77C0_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Net Income (Loss) Per Share</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company follows the two-class method when computing net income (loss) per share, as the Company has issued shares that meet the definition of participating securities. The two-class method determines net income (loss) per share for each class of common and participating securities according to dividends declared or accumulated and participation rights in undistributed earnings. The two-class method requires income available to common stockholders for the period to be allocated between common and participating securities based upon their respective rights to receive dividends as if all income for the period had been distributed.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt; TEXT-INDENT: 4%"> Basic net income (loss) per share attributable to common stockholders is computed by dividing the net income (loss) attributable to common stockholders by the weighted average number of shares of common stock outstanding for the period. Diluted net income (loss) attributable to common stockholders is computed by adjusting income (loss) attributable to common stockholders to reallocate undistributed earnings based on the potential impact of dilutive securities, including outstanding stock options and unvested restricted common stock. Diluted net income (loss) per share attributable to common stockholders is computed by dividing the diluted net income (loss) attributable to common stockholders by the weighted average number of common shares outstanding for the period, including potential dilutive common shares assuming the dilutive effect of outstanding stock options and unvested restricted common stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company’s redeemable convertible preferred stock contractually entitles the holders of such shares to participate in dividends but does not contractually require the holders of such shares to participate in losses of the Company. Similarly, restricted stock awards granted by the Company entitle the holder of such awards to dividends declared or paid by the board of directors, regardless of whether such awards are unvested, as if such shares were outstanding common shares at the time of the dividend. However, the unvested restricted stock awards are not entitled to share in the residual net assets (deficit) of the Company. Accordingly, in periods in which the Company reports a net loss attributable to common stockholders, diluted net loss per share attributable to common stockholders is the same as basic net loss per share attributable to common stockholders, since dilutive common shares are not assumed to have been issued if their effect is anti-dilutive. The Company reported a net loss attributable to common stockholders for the years ended December 31, 2011, 2012 and 2013.</p> </div> </us-gaap:EarningsPerSharePolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:EarningsPerShareTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_5BF274AC-F16C-41D4-A0DB-76E14D13A972_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>9. Net Loss Per Share</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Net Loss Per Share</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Basic and diluted net loss per share attributable to common stockholders was calculated as follows for the years ended December 31, 2011, 2012 and 2013:</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 12pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="73%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: 'Times New Roman'"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="10" align="center"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: 'Times New Roman'"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2011</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Numerator:</p> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Net loss</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,157</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,880</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">(14,027</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Accretion of redeemable convertible preferred stock to redemption value</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(53</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(67</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(213</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 5em; TEXT-INDENT: -1em"> Net loss attributable to common stockholders</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,210</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,947</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(14,240</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Denominator:</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Weighted average common shares outstanding, basic and diluted</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">688,946</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">709,678</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">729,001</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Net loss per share attributable to common stockholders, basic and diluted</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(19.17</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(19.65</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(19.53</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company excluded the following common stock equivalents, outstanding as of December 31, 2011, 2012 and 2013, from the computation of diluted net loss per share attributable to common stockholders for the years ended December 31, 2011, 2012 and 2013 because they had an anti-dilutive impact due to the net loss attributable to common stockholders incurred for the periods.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 12pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="75%"></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: 'Times New Roman'"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="10" align="center"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: 'Times New Roman'"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2011</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Stock options to purchase common stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">916,094</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">591,427</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Unvested restricted common stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">24,548</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">10,615</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">940,642</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">602,042</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: rgb(0,0,0) 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 18pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> </div> </us-gaap:EarningsPerShareTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_B90318E5-E38F-4783-83F0-3CB691B1BE17_1_0"> <div> <p style="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> A reconciliation of the U.S. federal statutory income tax rate to the Company’s effective income tax rate is as follows:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="76%"></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="10" align="center" style="border-bottom:1.00pt solid #000000"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Federal statutory income tax rate</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34.0</td> <td nowrap="nowrap" valign="bottom">%) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34.0</td> <td nowrap="nowrap" valign="bottom">%) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34.0</td> <td nowrap="nowrap" valign="bottom">%) </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Federal and state research and development tax credit</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(6.4</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(1.2</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(9.0</td> <td nowrap="nowrap" valign="bottom">) </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Orphan drug tax credit</p> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(3.1</td> <td nowrap="nowrap" valign="bottom">) </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> State taxes, net of federal benefit</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(5.4</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(5.0</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(4.0</td> <td nowrap="nowrap" valign="bottom">) </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Meals and entertainment</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.1</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">— </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">— </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Stock-based compensation expense</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.2</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.2</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.6</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-top:0pt; margin-bottom:1pt; margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Nondeductible Australia research and development expenses</p> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.8</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">4.1</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Change in deferred tax asset valuation allowance</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">45.5</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">38.2</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">45.4</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Effective income tax rate</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.0</td> <td nowrap="nowrap" valign="bottom">% </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.0</td> <td nowrap="nowrap" valign="bottom">% </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.0</td> <td nowrap="nowrap" valign="bottom">% </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_B3720CA8-5956-4582-8786-C1486BAA1514_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The assumptions that the Company used to determine the fair value of the stock options granted to employees and directors are as follows, presented on a weighted average basis (the Company did not grant any stock options to employees or directors during the year ended December 31, 2012):</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="78%"></td> <td valign="bottom" width="9%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="9%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"> <b> Year Ended December 31, </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2011</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Risk-free interest rate</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.41</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.12</td> <td valign="bottom" nowrap="nowrap">% </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Expected term (in years)</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6.25</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6.25</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Expected volatility</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">78</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">85</td> <td valign="bottom" nowrap="nowrap">% </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Expected dividend yield</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0</td> <td valign="bottom" nowrap="nowrap">% </td> </tr> </table> </div> </us-gaap:ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_9001_11" unitRef="shares"> 718903 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_B27D47F3-E181-4656-870C-C8832CFB79CA_5001_6"> P7Y9M18D </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1> | |||||||||||||||||||||
| <us-gaap:ComprehensiveIncomePolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_26C1FD2D-6704-4FE0-97A1-635D9D9F8E48_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Comprehensive Loss</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Comprehensive loss includes net loss as well as other changes in stockholders’ equity (deficit) that result from transactions and economic events other than those with stockholders. For the years ended December 31, 2011, 2012 and 2013, there was no difference between net loss and comprehensive loss.</p> </div> </us-gaap:ComprehensiveIncomePolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:IncomeTaxPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_17B6A41A-805D-4192-B583-6CC8B39F19CC_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Income Taxes</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company accounts for income taxes using the asset and liability method, which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been recognized in the consolidated financial statements or in the Company’s tax returns. Deferred taxes are determined based on the difference between the financial statement and tax basis of assets and liabilities using enacted tax rates in effect in the years in which the differences are expected to reverse. Changes in deferred tax assets and liabilities are recorded in the provision for income taxes. The Company assesses the likelihood that its deferred tax assets will be recovered from future taxable income and, to the extent it believes, based upon the weight of available evidence, that it is more likely than not that all or a portion of deferred tax assets will not be realized, a valuation allowance is established through a charge to income tax expense. Potential for recovery of deferred tax assets is evaluated by estimating the future taxable profits expected and considering prudent and feasible tax planning strategies.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company accounts for uncertainty in income taxes recognized in the consolidated financial statements by applying a two-step process to determine the amount of tax benefit to be recognized. First, the tax position must be evaluated to determine the likelihood that it will be sustained upon external examination by the taxing authorities. If the tax position is deemed more-likely-than-not to be sustained, the tax position is then assessed to determine the amount of benefit to recognize in the consolidated financial statements. The amount of the benefit that may be recognized is the largest amount that has a greater than 50% likelihood of being realized upon ultimate settlement. The provision for income taxes includes the effects of any resulting tax reserves, or unrecognized tax benefits, that are considered appropriate as well as the related net interest and penalties.</p> </div> </us-gaap:IncomeTaxPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_6E1CA0D5-9302-4D7A-A084-9304050C8E0E_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company excluded the following common stock equivalents, outstanding as of December 31, 2011, 2012 and 2013, from the computation of diluted net loss per share attributable to common stockholders for the years ended December 31, 2011, 2012 and 2013 because they had an anti-dilutive impact due to the net loss attributable to common stockholders incurred for the periods.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="75%"></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="10" align="center"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2011</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Stock options to purchase common stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">916,094</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">591,427</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Unvested restricted common stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">24,548</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">10,615</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">940,642</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">602,042</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_7A4F4FA4-A9CB-4B52-9E5E-CBB00EC354FD_1_0"> <div> <p style="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> The following table summarizes the Company’s stock option activity since January 1, 2011:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="66%"></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Shares Issuable<br /> Under Options</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Weighted<br /> Average<br /> Exercise<br /> Price</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Weighted</b><br /> <b>Average</b><br /> <b>Remaining</b><br /> <b>Contractual</b><br /> <b>Term</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Aggregate<br /> Intrinsic<br /> Value</b></td> <td valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td colspan="2" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td colspan="2" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center"><b>(In years)</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td colspan="2" valign="bottom"> </td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Outstanding as of January 1, 2011</b></p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">440,301</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.75</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">8.5</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">216</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Granted</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">475,793</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.57</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Exercised</p> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Forfeited</p> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Outstanding as of December 31, 2011</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">916,094</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.19</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">8.7</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">354</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Granted</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7,961</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.57</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Exercised</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(16,069</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.88</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Forfeited</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(316,559</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.57</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Outstanding as of December 31, 2012</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">591,427</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.00</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7.1</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">342</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Granted</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">718,903</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">2.64</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Exercised</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Forfeited</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Outstanding as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.88</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7.8</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">10,185</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Options vested and expected to vest as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.88</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7.8</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">10,185</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Options exercisable as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">657,317</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.26</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">6.6</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">5,543</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> </table> </div> </us-gaap:ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_780167DC-C6E5-48FF-BF9F-B248C8D82D10_3_0" unitRef="iso4217_USD_per_shares"> 1.83 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:SummaryOfValuationAllowanceTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_E03A1B5D-9047-4BC9-82CA-765027D5DE48_1_0"> <div> <p style="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> Changes in the valuation allowance for deferred tax assets during the years ended December 31, 2011, 2012 and 2013 related primarily to the increase in net operating loss carryforwards, capitalized research and development expenses and research and development tax credit carryforwards and were as follows:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="76%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="10" align="center" style="border-bottom:1.00pt solid #000000"><b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Valuation allowance as of beginning of year</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">12,748</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">18,744</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">24,006</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Decreases recorded as benefit to income tax provision</p> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Increases recorded to income tax provision</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,996</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,262</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6,351</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Valuation allowance as of end of year</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">18,744</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">24,006</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">30,357</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:SummaryOfValuationAllowanceTextBlock> | |||||||||||||||||||||
| <dei:EntityIncorporationDateOfIncorporation contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_5D495B57-4DFD-4E3A-9346-41844C424F3F_1_0"> 2005-11-22 </dei:EntityIncorporationDateOfIncorporation> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_8" unitRef="pure"> 0.000 </us-gaap:EffectiveIncomeTaxRateContinuingOperations> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationTaxSettlementsOther contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_2" unitRef="pure"> -0.031 </us-gaap:EffectiveIncomeTaxRateReconciliationTaxSettlementsOther> | |||||||||||||||||||||
| <us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_0D3FBD8F-6255-45A8-8308-08D5E46A5DE2_1_1"> P3Y7M6D </us-gaap:EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_13" unitRef="iso4217_USD"> -15004000 </us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:RelatedPartyTransactionsDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_41E81046-DB75-434A-B89B-8B0992E54C39_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>14. Related Party Transactions</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> In October 2011, the Company entered into an agreement with a member of the board of directors under which the board member would also serve as a business development consultant. Under the terms of the agreement, the annual consulting fee was $80. Additionally, a success fee of $500 would be earned upon a change in control of the Company. During the years ended December 31, 2011 and 2012, the Company paid the board member $18 and $80, respectively, for consulting services. This agreement was terminated in 2012.</p> </div> </us-gaap:RelatedPartyTransactionsDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_86319BD1-1D1A-457A-AF6E-1F93417BC955_1_0"> <div> <p style="margin-top:6pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> The Company recorded stock-based compensation expense related to stock options and restricted common stock in the following expense categories of its statements of operations:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="80%"></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="10" align="center" style="border-bottom:1.00pt solid #000000"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Research and development</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">30</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">68</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">176</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> General and administrative</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">50</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">53</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">219</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">80</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">121</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">395</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_2_3" unitRef="pure"> 0.00 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_2_1"> P6Y3M </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1> | |||||||||||||||||||||
| <us-gaap:StockholdersEquityNoteStockSplitConversionRatio1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_1_11" unitRef="pure"> 6.28 </us-gaap:StockholdersEquityNoteStockSplitConversionRatio1> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_3" unitRef="pure"> -0.040 </us-gaap:EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes> | |||||||||||||||||||||
| <us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_74FC7BA2-D56E-4DB1-B39E-7ECA97F541AB_1_0"> <div> <p style="margin-top:6pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> Accrued expenses consisted of the following as of December 31, 2012 and 2013:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="87%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="6" align="center" style="border-bottom:1.00pt solid #000000"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Accrued payroll and related expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">74</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">49</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Accrued research and development expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,558</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">616</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Accrued professional fees</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">62</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">196</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Accrued other</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">39</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1,699</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">900</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfAccruedLiabilitiesTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="4" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_2_0" unitRef="pure"> 0.0112 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate> | |||||||||||||||||||||
| <us-gaap:UseOfEstimates contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_CD571378-18F7-4507-9ED9-8BF69F2939E6_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt"> <b>Use of Estimates</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the consolidated financial statements, and the reported amounts of expenses during the reporting periods. Significant estimates and assumptions reflected in these consolidated financial statements include, but are not limited to, the accrual of research and development expenses and the valuation of common stock and stock-based awards. Estimates are periodically reviewed in light of changes in circumstances, facts and experience. Actual results could differ from the Company’s estimates.</p> </div> </us-gaap:UseOfEstimates> | |||||||||||||||||||||
| <us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="0" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_14" unitRef="shares"> 729001 </us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_A7929DCA-730E-4B2F-B2D6-0E918F2CB322_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Cash Equivalents</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company considers all short-term, highly liquid investments with original maturities of ninety days or less at acquisition date to be cash equivalents. Cash equivalents, which consist of money market accounts, are stated at fair value.</p> </div> </us-gaap:CashAndCashEquivalentsPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:DefinedContributionPlanEmployerMatchingContributionPercent contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_2AE61126-4DAE-4074-8C25-1809A93C2510_1_0" unitRef="pure"> 0.02 </us-gaap:DefinedContributionPlanEmployerMatchingContributionPercent> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_7" unitRef="pure"> 0.454 </us-gaap:EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance> | |||||||||||||||||||||
| <us-gaap:IntangibleAssetsFiniteLivedPolicy contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_06DA7996-DAB1-4AE5-B9E2-474F3F147D4D_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Patent Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> All patent-related costs incurred in connection with filing and prosecuting patent applications are recorded as general and administrative expenses as incurred, as recoverability of such expenditures is uncertain.</p> </div> </us-gaap:IntangibleAssetsFiniteLivedPolicy> | |||||||||||||||||||||
| <us-gaap:PreferredStockTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_E336BCDB-E768-416C-AD26-D4D8D3EBFB86_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>6. Redeemable Convertible Preferred Stock</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> As of December 31, 2013, the Company’s Certificate of Incorporation, as amended and restated, authorizes the Company to issue 99,292,610 shares of $0.001 par value preferred stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company has issued Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock (collectively, the “Redeemable Preferred Stock”). The Redeemable Preferred Stock is classified outside of stockholders’ equity (deficit) because the shares contain redemption features that are not solely within the control of the Company.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> In June and December 2011, the Company issued a total of 8,923,884 shares of Series C redeemable convertible preferred stock at an issuance price equal to $0.9061 per share and received gross proceeds of $8,086. In connection with this financing, the Company paid total issuance costs of $33.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> In February 2012, the Company issued 7,808,400 shares of Series C redeemable convertible preferred stock at an issuance price equal to $0.9061 per share and received gross proceeds of $7,075. In connection with this financing, the Company paid total issuance costs of $8.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> In November 2012, the Company issued 6,653,988 shares of Series D redeemable convertible preferred stock at an issuance price equal to $1.3592 per share and received gross proceeds of $9,044. In connection with this financing, the Company paid total issuance costs of $54. Additionally, in November 2012, $6,000 of convertible promissory notes and $86 of accrued interest were converted into 4,975,260 shares of Series D redeemable convertible preferred stock (see Note 5).</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> In January 2013, the Company issued 4,381,914 shares of Series D redeemable convertible preferred stock at an issuance price equal to $1.3592 per share and received gross proceeds of $5,956. In connection with this financing, the Company paid total issuance costs of $1.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> In November 2013, the Company issued 16,110,473 shares of Series E redeemable convertible preferred stock at an issuance price equal to $2.1725 per share and received gross proceeds of $35,000. In connection with this financing, the Company paid total issuance costs of $156.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Redeemable Preferred Stock consisted of the following as of December 31, 2012:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="53%"></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Preferred<br /> Shares<br /> Authorized</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Preferred<br /> Shares<br /> Issued and<br /> Outstanding</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Liquidation<br /> Preference</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Carrying<br /> Value</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Common<br /> Stock Issuable<br /> Upon<br /> Conversion</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series A redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,250</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,222</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">854,018</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series B redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,402</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,335</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6,411,822</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series C redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,161</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,137</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,664,376</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series D redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,011,162</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">11,629,248</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,816</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,091</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,851,791</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">78,372,931</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">73,991,017</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">63,629</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">62,785</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">11,782,007</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Redeemable Preferred Stock consisted of the following as of December 31, 2013:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="54%"></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Preferred<br /> Shares<br /> Authorized</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Preferred<br /> Shares<br /> Issued and<br /> Outstanding</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Liquidation<br /> Preference</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Carrying<br /> Value</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Common<br /> Stock Issuable<br /> Upon<br /> Conversion</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series A redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,250</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,229</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">854,018</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series B redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,402</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,351</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6,411,822</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series C redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,161</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,144</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,664,376</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series D redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,011,162</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,011,162</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">21,775</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">21,226</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,549,548</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Series E redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">20,919,679</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,110,473</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">35,000</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">34,847</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,565,361</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">99,292,610</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">94,483,404</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">104,588</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">103,797</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,045,125</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt; TEXT-INDENT: 4%"> The holders of the Redeemable Preferred Stock have the following rights and preferences:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Voting Rights</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The holders of Redeemable Preferred Stock are entitled to vote, together with the holders of common stock, on all matters submitted to stockholders for a vote. Holders of all Redeemable Preferred Stock have the right to vote the number of shares equal to the number of shares of common stock into which such Redeemable Preferred Stock could convert on the record date for determination of stockholders entitled to vote.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Dividends</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company may not declare, pay or set aside any dividends on shares of any other class or series of capital stock of the Company unless the holders of the Redeemable Preferred Stock then outstanding shall first receive a dividend on each outstanding share of Redeemable Preferred Stock in an amount at least equal to (i) in the case of a dividend on common stock or any class or series that is convertible into common stock, that dividend per share of Redeemable Preferred Stock as would equal the product of (A) the dividend payable on each share of such class or series determined, if applicable, as if all shares of such class or series had been converted into common stock and (B) the number of shares of common stock issuable upon conversion of a share of Redeemable Preferred Stock, or (ii) in the case of a dividend on any class or series that is not convertible into common stock, at a rate per share of Redeemable Preferred Stock determined by (A) dividing the amount of the dividend payable on each share of such class or series of capital stock by the original issuance price of such class or series of capital stock (subject to appropriate adjustment in the event of any stock dividend, stock split, combination of or other similar recapitalization affecting such shares) and (B) multiplying such fraction by an amount equal to the Original Issue Price (as defined below) of each series of Redeemable Preferred Stock. If the Company declares, pays or sets aside, on the same date, a dividend on shares of more than one class or series of capital stock of the Company, the dividend payable to the holders of the Redeemable Preferred Stock shall be calculated based upon the dividend on the class or series of capital stock that would result in the highest Redeemable Preferred Stock dividend. The Original Issue Price for Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock is $0.419463, $0.75503, $0.9061, $1.3592 and $2.1725, respectively, per share, subject to appropriate adjustment in the event of any stock dividend, stock split, combination or other similar recapitalization with respect to the Redeemable Preferred Stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Liquidation Preference</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> In the event of any liquidation, voluntary or involuntary, exclusive out-license of all or substantially all of the intellectual property of the Company, dissolution or winding up of the Company or Deemed Liquidation Event (as defined below), the Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stockholders are entitled to receive, in preference to all other stockholders, and to the extent available, an amount equal to the Original Issue Price per share, adjusted for any stock dividends, stock splits or reclassifications, plus all dividends declared but unpaid. In the event that proceeds are not sufficient to permit payment in full to these holders, the proceeds will be ratably distributed among the Series A, Series B, Series C, Series D and Series E holders in proportion to the full preferential amount each such holder is otherwise entitled to receive.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> After payments have been made in full to the holders of the Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock, then, to the extent available, holders of the common stock and holders of the Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock will receive the remaining amounts available for distribution ratably in proportion to the number of common shares held by them or issuable to them upon conversion of their redeemable convertible preferred stock into common stock. The distributions are subject to an overall distribution limit of the greater of (i) two times the amount the holders of the Redeemable Preferred Stock are entitled to based on their preference payment and (ii) the amount such holder would have received if such holder had converted shares of the Redeemable Preferred Stock into common stock immediately prior to such dissolution, liquidation, exclusive out-license of all or substantially all of the intellectual property, or winding up of the Company or Deemed Liquidation Event.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Unless the holders of at least 70% of the then outstanding shares of the Redeemable Preferred Stock, voting together as a single class on an as-converted basis, elect otherwise, a Deemed Liquidation Event shall include a sale of the Company, a sale of the capital stock representing a majority of the voting power or a merger or consolidation of the Company into or with another corporation in which the existing Company holds less than a majority of the voting power of the surviving or resulting corporation, or the sale, lease, transfer, exclusive license or other disposition, in a single transaction or series of related transactions, by the Company of all or substantially all of the assets of the Company.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Conversion</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Each share of Redeemable Preferred Stock is convertible into common stock at the option of the stockholder at any time after the date of issuance. Each share of the preferred stock will automatically be converted into shares of common stock, at the applicable Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock conversion ratio then in effect, upon a qualified public offering with net proceeds of not less than $35,000. The conversion ratio of the Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock, as defined, is determined by dividing the Original Issue Price of each series of preferred stock by the Conversion Price of each series. The Conversion Price of each series shall be $2.63422764 for Series A, $4.7415884 for Series B, $5.690308 for Series C, $8.535776 for Series D and $13.6433 for Series E. The Conversion Price is subject to adjustment as set forth in the Company’s Certificate of Incorporation, as amended and restated, unless at least a majority of the Series A holders, at least 70% of each of Series B or Series C holders, at least 65% of Series D holders and at least a majority of the Series E holders, voting separately as a class with respect to their series, agree that no such adjustment shall be made to their series. As of December 31, 2013, all outstanding shares of Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock were convertible into common stock on a 6.28-for-1 basis.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Redemption Rights</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> At the written election of at least 70% of the holders of the Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock, voting together as a single class on an as-converted basis, the shares of Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock outstanding are redeemable, at any time on or after November 22, 2017, in three equal annual installments commencing sixty days after receipt of the required vote at the Original Issue Price per share of Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock plus all declared but unpaid dividends thereon.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The carrying values of the Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock are being accreted to their redemption values through their respective redemption dates.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Reissuance</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Shares of any Series A, Series B, Series C, Series D or Series E redeemable convertible preferred stock that are redeemed or converted will be retired or canceled and not reissued by the Company.</p> </div> </us-gaap:PreferredStockTextBlock> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_39E5AB0F-C7EF-409F-B01B-ADEA74554AEB_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Property and Equipment</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Property and equipment are stated at cost less accumulated depreciation. Depreciation expense is recognized using the straight-line method over a five-year estimated useful life for both furniture and fixtures and office equipment. Expenditures for repairs and maintenance of assets are charged to expense as incurred. Upon retirement or sale, the cost and related accumulated depreciation of assets disposed of are removed from the accounts and any resulting gain or loss is included in loss from operations.</p> </div> </us-gaap:PropertyPlantAndEquipmentPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentUsefulLife contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_443745C8-A301-481B-9A70-AB5D0D3B3A94_1_0"> P5Y </us-gaap:PropertyPlantAndEquipmentUsefulLife> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentExpensePolicy contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_52EA2DD1-C054-4CB0-B7F8-B1119B2979A8_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Research and Development Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Research and development costs are expensed as incurred. Included in research and development expenses are wages, stock-based compensation and benefits of employees, third-party license fees and other operational costs related to the Company’s research and development activities, including facility-related expenses and external costs of outside vendors engaged to conduct both pre-clinical studies and clinical trials. The Company records research and development expenses net of any research and development tax incentives the Company is entitled to receive from government authorities.</p> </div> </us-gaap:ResearchAndDevelopmentExpensePolicy> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_B27D47F3-E181-4656-870C-C8832CFB79CA_5001_5"> P7Y9M18D </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2> | |||||||||||||||||||||
| <us-gaap:StockholdersEquityNoteDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_BBB308CD-5AE1-40C5-8388-BC36BD03F565_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>7. Common Stock</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> As of December 31, 2013, the Company’s Certificate of Incorporation, as amended and restated, authorizes the Company to issue 115,000,000 shares of $0.001 par value common stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Each share of common stock entitles the holder to one vote on all matters submitted to a vote of the Company’s stockholders. Common stockholders are entitled to receive dividends, as may be declared by the board of directors, if any, subject to the preferential dividend rights of the Redeemable Preferred Stock. When dividends are declared on shares of common stock, the Company must declare at the same time a dividend payable to the holders of Redeemable Preferred Stock equivalent to the dividend amount they would receive if each preferred share were converted into common stock. The Company may not pay dividends to common stockholders until all dividends accrued or declared but unpaid on the Redeemable Preferred Stock have been paid in full. As of December 31, 2013, no dividends had been declared.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> During the year ended December 31, 2013, the Company reacquired and retired 6,635 shares of restricted common stock, at cost, that were forfeited by a former employee.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of December 31, 2013, the Company had reserved 16,726,699 shares of common stock for the conversion of the outstanding shares of Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock (see Note 6) and the exercise of stock options and issuance of common stock under the Company’s Amended and Restated 2006 Stock Option Plan (see Note 8).</p> </div> </us-gaap:StockholdersEquityNoteDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:BusinessDescriptionAndBasisOfPresentationTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_B1A8D5BE-2AAF-4559-9547-F51319A2FBF0_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt"> <b>1. Nature of the Business and Basis of Presentation</b></p> <!-- xbrl,body --> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Zafgen, Inc. (the “Company”) was incorporated on November 22, 2005 under the laws of the State of Delaware. The Company is a biopharmaceutical company dedicated to significantly improving the health and well-being of patients affected by obesity. Beloranib, the Company’s lead product candidate, is a novel, first-in-class, twice-weekly subcutaneous injection being developed for the treatment of multiple indications, including obesity and hyperphagia in Prader-Willi Syndrome patients, craniopharyngioma-associated obesity, and severe obesity in the general population. Since its inception, the Company has devoted substantially all of its efforts to research and development, recruiting management, acquiring operating assets and raising capital.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company is subject to risks common to companies in the biotechnology industry including, but not limited to, new technological innovations, protection of proprietary technology, dependence on key personnel, compliance with government regulations and the need to obtain additional financing. Product candidates currently under development will require significant additional research and development efforts, including extensive pre-clinical and clinical testing and regulatory approval, prior to commercialization. These efforts require significant amounts of additional capital, adequate personnel infrastructure, and extensive compliance-reporting capabilities.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company’s product candidates are all in the development stage. There can be no assurance that the Company’s research and development will be successfully completed, that adequate protection for the Company’s intellectual property will be obtained, that any products developed will obtain necessary government regulatory approval or that any approved products will be commercially viable. Even if the Company’s product development efforts are successful, it is uncertain when, if ever, the Company will generate significant revenue from product sales. The Company operates in an environment of rapid change in technology and substantial competition from pharmaceutical and biotechnology companies. In addition, the Company is dependent upon the services of its employees and consultants.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company’s consolidated financial statements have been prepared on the basis of continuity of operations, realization of assets and the satisfaction of liabilities in the ordinary course of business. The Company has experienced negative cash flows and has an accumulated deficit of $68,907 as of December 31, 2013. The Company expects that its existing cash and cash equivalents as of December 31, 2013 will enable the Company to fund its operating expenses and capital expenditure requirements for at least twelve months from the balance sheet date. The future viability of the Company is largely dependent on its ability to generate cash from operating activities or to raise additional capital to finance its operations. The Company’s failure to raise capital as and when needed could have a negative impact on its financial condition and ability to pursue its business strategies.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company is seeking to complete an initial public offering of its common stock. Upon a successful qualified public offering with net proceeds of not less than $35,000, the Company’s outstanding redeemable convertible preferred stock will automatically convert into shares of common stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> In the event the Company does not complete an initial public offering, the Company expects to seek additional funding through private financings, debt financing, collaboration agreements or government grants. The Company may not be able to obtain financing on acceptable terms, or at all, and the Company may not be able to enter into collaboration arrangements or obtain government grants. The terms of any financing may adversely affect the holdings or the rights of the Company’s stockholders. If the Company is unable to obtain funding, the Company could be forced to delay, reduce or eliminate its research and development programs, product portfolio expansion or commercialization efforts, which could adversely affect its business prospects. Although management continues to pursue these plans, there is no assurance that the Company will be successful in obtaining sufficient funding on terms acceptable to the Company to fund continuing operations, if at all.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries, Zafgen Securities Corporation, Zafgen Australia Pty Limited, and Zafgen Animal Health, LLC. All significant intercompany balances and transactions have been eliminated.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The accompanying consolidated financial statements have been prepared in conformity with accounting principles generally accepted in the United States of America (“GAAP”).</p> </div> </us-gaap:BusinessDescriptionAndBasisOfPresentationTextBlock> | |||||||||||||||||||||
| <us-gaap:DeferredChargesPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_0156F017-7F0E-4BEE-9973-B884C23CC3B2_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Deferred Offering Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company capitalizes certain legal, accounting and other third-party fees that are directly associated with in-process equity financings as other assets until such financings are consummated. After consummation of the equity financing, these costs are recorded in stockholders’ equity (deficit) as a reduction of additional paid-in capital generated as a result of the offering or as a reduction to the carrying value of preferred stock issued. As of December 31, 2013, the Company recorded $743 of deferred offering costs, included in other assets in the accompanying consolidated balance sheet, in contemplation of a probable 2014 equity financing. Should the equity financing no longer be considered probable of being consummated, the deferred offering costs would be expensed immediately as a charge to operating expenses in the consolidated statement of operations. The Company did not record any deferred offering costs as of December 31, 2012.</p> </div> </us-gaap:DeferredChargesPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:IncomeTaxDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_0FD1FAAB-6505-4A41-AE59-A8CD44FAB05A_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>11. Income Taxes</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> During the years ended December 31, 2011, 2012 and 2013, the Company recorded no income tax benefits for the net operating losses incurred in each year due to its uncertainty of realizing a benefit from those items.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> A reconciliation of the U.S. federal statutory income tax rate to the Company’s effective income tax rate is as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="76%"></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="10" align="center"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Federal statutory income tax rate</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34.0</td> <td valign="bottom" nowrap="nowrap">%) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34.0</td> <td valign="bottom" nowrap="nowrap">%) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34.0</td> <td valign="bottom" nowrap="nowrap">%) </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Federal and state research and development tax credit</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(6.4</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(1.2</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(9.0</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Orphan drug tax credit</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(3.1</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> State taxes, net of federal benefit</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(5.4</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(5.0</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(4.0</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Meals and entertainment</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.1</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">— </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">— </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Stock-based compensation expense</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.2</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.2</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.6</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="MARGIN-BOTTOM: 1pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; MARGIN-TOP: 0pt; TEXT-INDENT: -1em"> Nondeductible Australia research and development expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.8</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">4.1</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Change in deferred tax asset valuation allowance</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">45.5</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">38.2</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">45.4</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Effective income tax rate</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.0</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.0</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.0</td> <td valign="bottom" nowrap="nowrap">% </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt; TEXT-INDENT: 4%"> Net deferred tax assets as of December 31, 2012 and 2013 consisted of the following:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="82%"></td> <td valign="bottom" width="7%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="7%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Accrued expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">46</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">18</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Other temporary differences</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 5em; TEXT-INDENT: -1em"> Total current deferred tax assets</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">47</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">20</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Noncurrent deferred tax assets:</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Capitalized research and development expenses</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,676</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">19,856</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Net operating loss carryforwards</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">3,209</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">4,021</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Tax credit carryforwards</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">3,656</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,579</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Capitalized legal expenses</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">385</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">790</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Stock-based compensation</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">33</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">91</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 5em; TEXT-INDENT: -1em"> Total noncurrent deferred tax assets</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">23,959</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,337</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 5em; TEXT-INDENT: -1em"> Total gross deferred tax assets</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">24,006</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,357</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Valuation allowance</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(24,006</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(30,357</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 5em; TEXT-INDENT: -1em"> Net deferred tax assets</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Changes in the valuation allowance for deferred tax assets during the years ended December 31, 2011, 2012 and 2013 related primarily to the increase in net operating loss carryforwards, capitalized research and development expenses and research and development tax credit carryforwards and were as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="76%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="10" align="center"><b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Valuation allowance as of beginning of year</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">12,748</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">18,744</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">24,006</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Decreases recorded as benefit to income tax provision</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Increases recorded to income tax provision</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,996</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,262</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6,351</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Valuation allowance as of end of year</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">18,744</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">24,006</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">30,357</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of December 31, 2013, the Company had net operating loss carryforwards for federal and state income tax purposes of $10,548 and $8,226, respectively, which begin to expire in 2026 and 2014, respectively. The Company also had an additional $16 of federal and state net operating losses not reflected above that were attributable to stock option exercises, which will be recorded as an increase in additional paid-in capital once they are realized in accordance with accounting for stock-based compensation awards. As of December 31, 2013, the Company also had available research and development tax credit carryforwards for federal and state income tax purposes of $4,706 and $1,322, respectively, which begin to expire in 2026 and 2021, respectively. Utilization of the net operating loss carryforwards and research and development tax credit carryforwards may be subject to a substantial annual limitation under Section 382 of the Internal Revenue Code of 1986 due to ownership changes that have occurred previously or that could occur in the future. These ownership changes may limit the amount of carryforwards that can be utilized annually to offset future taxable income. In general, an ownership change, as defined by Section 382, results from transactions increasing the ownership of certain shareholders or public groups in the stock of a corporation by more than 50% over a three-year period. The Company has not conducted a study to assess whether a change of control has occurred or whether there have been multiple changes of control since inception due to the significant complexity and cost associated with such a study. If the Company has experienced a change of control, as defined by Section 382, at any time since inception, utilization of the net operating loss carryforwards or research and development tax credit carryforwards would be subject to an annual limitation under Section 382, which is determined by first multiplying the value of the Company’s stock at the time of the ownership change by the applicable long-term tax-exempt rate, and then could be subject to additional adjustments, as required. Any limitation may result in expiration of a portion of the net operating loss carryforwards or research and development tax credit carryforwards before utilization. Further, until a study is completed and any limitation is known, no amounts are being presented as an uncertain tax position.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of December 31, 2012 and 2013, the Company’s gross deferred tax asset balance of $24,006 and $30,357, respectively, was comprised principally of net operating loss carryforwards, capitalized research and development expenses and research and development tax credit carryforwards. During the years ended December 31, 2011, 2012 and 2013, gross deferred tax assets increased due to additional net operating loss carryforwards, research and development tax credits generated and additional research and development expenses capitalized for tax purposes.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company has evaluated the positive and negative evidence bearing upon its ability to realize the deferred tax assets. Management has considered the Company’s history of cumulative net losses incurred since inception and its lack of commercialization of any products or generation of any revenue from product sales since inception and has concluded that it is more likely than not that the Company will not realize the benefits of the deferred tax assets. Accordingly, a full valuation allowance has been established against the deferred tax assets as of December 31, 2012 and 2013. Management reevaluates the positive and negative evidence at each reporting period.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company has not recorded any amounts for unrecognized tax benefits as of December 31, 2012 or 2013.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company files tax returns as prescribed by the tax laws of the jurisdictions in which it operates. In the normal course of business, the Company is subject to examination by federal and state jurisdictions, where applicable. There are currently no pending income tax examinations. The Company’s tax years are still open under statute from 2010 to the present. Earlier years may be examined to the extent that tax credit or net operating loss carryforwards are used in future periods. The Company’s policy is to record interest and penalties related to income taxes as part of its income tax provision.</p> </div> </us-gaap:IncomeTaxDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_BC50026F-0D1C-4402-BE11-9606918CED87_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Related to these license agreements, the Company made payments and recorded research and development expenses in its consolidated statements of operations as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="78%"></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="10" align="center"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Licensing, milestone and license maintenance fees</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">1,055</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">150</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap">$</td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ResearchAndDevelopmentArrangementContractToPerformForOthersTextBlock> | |||||||||||||||||||||
| <us-gaap:ResearchDevelopmentAndComputerSoftwareDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_DD487A2E-901B-4651-9A82-EFB0EE7332B6_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>13. Australia Research and Development Tax Incentive</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Australian government has established a research and development tax incentive to encourage industry investment in research and development, which is available to companies incorporated under an Australian law that have core research and development activities. The Company established Zafgen Australia Pty Limited, a wholly owned subsidiary, in October 2012 to carry out certain research and development activities. As this subsidiary meets the eligibility requirements of the Australian tax law, it is eligible to receive a 45% refundable tax incentive for qualified research and development activities. For the years ended December 31, 2012 and 2013, $630 and $1,237, respectively, was recorded as a reduction to research and development expenses in the consolidated statements of operations, representing 45% of the Company’s qualified research and development spending in Australia. The refund is denominated in Australian dollars and, therefore, the receivable is re-measured into U.S. dollars as of each reporting date. For the year ended December 31, 2013, the Company recorded in its consolidated statements of operations unrealized foreign currency exchange (gains) losses of $250 related to this tax incentive receivable. The Company did not have any foreign exchange gains or losses related to this receivable for periods prior to 2013. As of December 31, 2012 and 2013, the Company’s tax incentive receivable from the Australian government was $630 and $1,617.</p> </div> </us-gaap:ResearchDevelopmentAndComputerSoftwareDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_B3E9171E-19C7-4DB2-9ACD-A996282A26C2_1_0"> <div> <p style="margin-top:0pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> Net deferred tax assets as of December 31, 2012 and 2013 consisted of the following:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="82%"></td> <td valign="bottom" width="7%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="7%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="6" align="center" style="border-bottom:1.00pt solid #000000"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Accrued expenses</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">46</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">18</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Other temporary differences</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:5.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Total current deferred tax assets</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">47</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">20</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Noncurrent deferred tax assets:</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Capitalized research and development expenses</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,676</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">19,856</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Net operating loss carryforwards</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">3,209</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">4,021</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Tax credit carryforwards</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">3,656</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,579</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Capitalized legal expenses</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">385</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">790</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Stock-based compensation</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">33</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">91</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:5.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Total noncurrent deferred tax assets</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">23,959</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,337</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:5.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Total gross deferred tax assets</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">24,006</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,357</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Valuation allowance</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(24,006</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(30,357</td> <td nowrap="nowrap" valign="bottom">) </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:5.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Net deferred tax assets</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom">$</td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom">$</td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_E6EB8DE3-E2A8-4B63-9057-A580C9DD4B3B_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Basic and diluted net loss per share attributable to common stockholders was calculated as follows for the years ended December 31, 2011, 2012 and 2013:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="73%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="10" align="center"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2011</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Numerator:</p> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Net loss</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,157</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,880</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">(14,027</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Accretion of redeemable convertible preferred stock to redemption value</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(53</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(67</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(213</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 5em; TEXT-INDENT: -1em"> Net loss attributable to common stockholders</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,210</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(13,947</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(14,240</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Denominator:</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Weighted average common shares outstanding, basic and diluted</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">688,946</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">709,678</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">729,001</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Net loss per share attributable to common stockholders, basic and diluted</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(19.17</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(19.65</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">(19.53</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_25ACE8B4-F867-4A6A-A841-6D001793A927_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Future minimum lease payments for its operating lease as of December 31, 2013 were as follows:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="95%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom" nowrap="nowrap"> <p style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman; BORDER-BOTTOM: #000000 1pt solid; WIDTH: 92.45pt"> <b>Year Ending December 31,</b></p> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> 2014</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">64</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Total</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">64</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_B27D47F3-E181-4656-870C-C8832CFB79CA_5001_7"> P6Y7M6D </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_9001_11" unitRef="iso4217_USD_per_shares"> 2.64 </us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:SignificantAccountingPoliciesTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_87C1B18D-113F-4390-BF16-1A7ACCC02CEA_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>2. Summary of Significant Accounting Policies</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Use of Estimates</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the consolidated financial statements, and the reported amounts of expenses during the reporting periods. Significant estimates and assumptions reflected in these consolidated financial statements include, but are not limited to, the accrual of research and development expenses and the valuation of common stock and stock-based awards. Estimates are periodically reviewed in light of changes in circumstances, facts and experience. Actual results could differ from the Company’s estimates.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Cash Equivalents</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company considers all short-term, highly liquid investments with original maturities of ninety days or less at acquisition date to be cash equivalents. Cash equivalents, which consist of money market accounts, are stated at fair value.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Concentration of Credit Risk and of Significant Suppliers</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Financial instruments that potentially expose the Company to concentrations of credit risk consist primarily of cash and cash equivalents. The Company has all cash and cash equivalents balances at one accredited financial institution, in amounts that exceed federally insured limits. The Company does not believe that it is subject to unusual credit risk beyond the normal credit risk associated with commercial banking relationships.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company is dependent on third-party manufacturers to supply products for research and development activities in its programs. In particular, the Company relies and expects to continue to rely on a small number of manufacturers to supply it with its requirements for the active pharmaceutical ingredients and formulated drugs related to these programs. These programs could be adversely affected by a significant interruption in the supply of active pharmaceutical ingredients and formulated drugs.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Fair Value Measurements</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Certain assets and liabilities are carried at fair value under GAAP. Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. Financial assets and liabilities carried at fair value are to be classified and disclosed in one of the following three levels of the fair value hierarchy, of which the first two are considered observable and the last is considered unobservable:</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 6pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 1—Quoted prices in active markets for identical assets or liabilities.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 6pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 2—Observable inputs (other than Level 1 quoted prices) such as quoted prices in active markets for similar assets or liabilities, quoted prices in markets that are not active for identical or similar assets or liabilities, or other inputs that are observable or can be corroborated by observable market data.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 6pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 3—Unobservable inputs that are supported by little or no market activity and that are significant to determining the fair value of the assets or liabilities, including pricing models, discounted cash flow methodologies and similar techniques.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company’s cash equivalents of $8,001 as of December 31, 2012 and $26,501 as of December 31, 2013 were carried at fair value based on quoted prices in active markets, a Level 1 measurement. The carrying values of accounts payable and accrued expenses approximate their fair value due to the short-term nature of these liabilities.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Deferred Offering Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company capitalizes certain legal, accounting and other third-party fees that are directly associated with in-process equity financings as other assets until such financings are consummated. After consummation of the equity financing, these costs are recorded in stockholders’ equity (deficit) as a reduction of additional paid-in capital generated as a result of the offering or as a reduction to the carrying value of preferred stock issued. As of December 31, 2013, the Company recorded $743 of deferred offering costs, included in other assets in the accompanying consolidated balance sheet, in contemplation of a probable 2014 equity financing. Should the equity financing no longer be considered probable of being consummated, the deferred offering costs would be expensed immediately as a charge to operating expenses in the consolidated statement of operations. The Company did not record any deferred offering costs as of December 31, 2012.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Property and Equipment</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Property and equipment are stated at cost less accumulated depreciation. Depreciation expense is recognized using the straight-line method over a five-year estimated useful life for both furniture and fixtures and office equipment. Expenditures for repairs and maintenance of assets are charged to expense as incurred. Upon retirement or sale, the cost and related accumulated depreciation of assets disposed of are removed from the accounts and any resulting gain or loss is included in loss from operations.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Impairment of Long-Lived Assets</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Long-lived assets consist of property and equipment. Long-lived assets to be held and used are tested for recoverability whenever events or changes in business circumstances indicate that the carrying amount of the assets may not be fully recoverable. Factors that the Company considers in deciding when to perform an impairment review include significant underperformance of the business in relation to expectations, significant negative industry or economic trends, and significant changes or planned changes in the use of the assets. If an impairment review is performed to evaluate a long-lived asset for recoverability, the Company compares forecasts of undiscounted cash flows expected to result from the use and eventual disposition of the long-lived asset to its carrying value. An impairment loss would be recognized when estimated undiscounted future cash flows expected to result from the use of an asset are less than its carrying amount. The impairment loss would be based on the excess of the carrying value of the impaired asset over its fair value, determined based on discounted cash flows. To date, the Company has not recorded any impairment losses on long-lived assets.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Research and Development Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Research and development costs are expensed as incurred. Included in research and development expenses are wages, stock-based compensation and benefits of employees, third-party license fees and other operational costs related to the Company’s research and development activities, including facility-related expenses and external costs of outside vendors engaged to conduct both pre-clinical studies and clinical trials. The Company records research and development expenses net of any research and development tax incentives the Company is entitled to receive from government authorities.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Research Contract Costs and Accruals</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company has entered into various research and development contracts with research institutions and other companies both inside and outside of the United States. These agreements are generally cancelable, and related payments are recorded as research and development expenses as incurred. The Company records accruals for estimated ongoing research costs. When evaluating the adequacy of the accrued liabilities, the Company analyzes progress of the studies, including the phase or completion of events, invoices received and contracted costs. Significant judgments and estimates are made in determining the accrued balances at the end of any reporting period. Actual results could differ from the Company’s estimates. The Company’s historical accrual estimates have not been materially different from the actual costs.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Patent Costs</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> All patent-related costs incurred in connection with filing and prosecuting patent applications are recorded as general and administrative expenses as incurred, as recoverability of such expenditures is uncertain.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Accounting for Stock-Based Compensation</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company measures all stock options and other stock-based awards granted to employees and directors at the fair value on the date of the grant using the Black-Scholes option-pricing model. The fair value of the awards is recognized as expense, net of estimated forfeitures, over the requisite service period, which is generally the vesting period of the respective award. The straight-line method of expense recognition is applied to all awards with service-only conditions.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> For stock-based awards granted to consultants and nonemployees, compensation expense is recognized over the period during which services are rendered by such consultants and nonemployees until completed. At the end of each financial reporting period prior to completion of the service, the fair value of these awards is re-measured using the then-current fair value of the Company’s common stock and updated assumption inputs in the Black-Scholes option-pricing model.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company classifies stock-based compensation expense in its consolidated statement of operations and comprehensive loss in the same manner in which the award recipient’s payroll costs are classified or in which the award recipients’ service payments are classified.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company recognizes compensation expense for only the portion of awards that are expected to vest. In developing a forfeiture rate estimate, the Company has considered its historical experience to estimate pre-vesting forfeitures for service-based awards. The impact of a forfeiture rate adjustment will be recognized in full in the period of adjustment, and if the actual forfeiture rate is materially different from the Company’s estimate, the Company may be required to record adjustments to stock-based compensation expense in future periods.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Income Taxes</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company accounts for income taxes using the asset and liability method, which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been recognized in the consolidated financial statements or in the Company’s tax returns. Deferred taxes are determined based on the difference between the financial statement and tax basis of assets and liabilities using enacted tax rates in effect in the years in which the differences are expected to reverse. Changes in deferred tax assets and liabilities are recorded in the provision for income taxes. The Company assesses the likelihood that its deferred tax assets will be recovered from future taxable income and, to the extent it believes, based upon the weight of available evidence, that it is more likely than not that all or a portion of deferred tax assets will not be realized, a valuation allowance is established through a charge to income tax expense. Potential for recovery of deferred tax assets is evaluated by estimating the future taxable profits expected and considering prudent and feasible tax planning strategies.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company accounts for uncertainty in income taxes recognized in the consolidated financial statements by applying a two-step process to determine the amount of tax benefit to be recognized. First, the tax position must be evaluated to determine the likelihood that it will be sustained upon external examination by the taxing authorities. If the tax position is deemed more-likely-than-not to be sustained, the tax position is then assessed to determine the amount of benefit to recognize in the consolidated financial statements. The amount of the benefit that may be recognized is the largest amount that has a greater than 50% likelihood of being realized upon ultimate settlement. The provision for income taxes includes the effects of any resulting tax reserves, or unrecognized tax benefits, that are considered appropriate as well as the related net interest and penalties.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Segment Data</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company’s singular focus is on advancing novel therapeutics for patients suffering from severe obesity and obesity-related disorders. No revenue has been generated since inception, and all tangible assets are held in the United States.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Comprehensive Loss</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Comprehensive loss includes net loss as well as other changes in stockholders’ equity (deficit) that result from transactions and economic events other than those with stockholders. For the years ended December 31, 2011, 2012 and 2013, there was no difference between net loss and comprehensive loss.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Net Income (Loss) Per Share</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company follows the two-class method when computing net income (loss) per share, as the Company has issued shares that meet the definition of participating securities. The two-class method determines net income (loss) per share for each class of common and participating securities according to dividends declared or accumulated and participation rights in undistributed earnings. The two-class method requires income available to common stockholders for the period to be allocated between common and participating securities based upon their respective rights to receive dividends as if all income for the period had been distributed.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 12pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> </p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 0pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Basic net income (loss) per share attributable to common stockholders is computed by dividing the net income (loss) attributable to common stockholders by the weighted average number of shares of common stock outstanding for the period. Diluted net income (loss) attributable to common stockholders is computed by adjusting income (loss) attributable to common stockholders to reallocate undistributed earnings based on the potential impact of dilutive securities, including outstanding stock options and unvested restricted common stock. Diluted net income (loss) per share attributable to common stockholders is computed by dividing the diluted net income (loss) attributable to common stockholders by the weighted average number of common shares outstanding for the period, including potential dilutive common shares assuming the dilutive effect of outstanding stock options and unvested restricted common stock.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> The Company’s redeemable convertible preferred stock contractually entitles the holders of such shares to participate in dividends but does not contractually require the holders of such shares to participate in losses of the Company. Similarly, restricted stock awards granted by the Company entitle the holder of such awards to dividends declared or paid by the board of directors, regardless of whether such awards are unvested, as if such shares were outstanding common shares at the time of the dividend. However, the unvested restricted stock awards are not entitled to share in the residual net assets (deficit) of the Company. Accordingly, in periods in which the Company reports a net loss attributable to common stockholders, diluted net loss per share attributable to common stockholders is the same as basic net loss per share attributable to common stockholders, since dilutive common shares are not assumed to have been issued if their effect is anti-dilutive. The Company reported a net loss attributable to common stockholders for the years ended December 31, 2011, 2012 and 2013.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Recently Issued and Adopted Accounting Pronouncements</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In June 2011, the Financial Accounting Standards Board (“FASB”) issued an amendment to the accounting guidance for presentation of comprehensive income. Under the amended guidance, a company may present the total of comprehensive income, the components of net income, and the components of other comprehensive income either in a single continuous statement of comprehensive income or in two separate but consecutive statements. In either case, a company is required to present each component of net income along with total net income, each component of other comprehensive income along with a total for other comprehensive income, and a total amount for comprehensive income. The amendment is effective for fiscal years ending, and interim periods within those years, beginning after December 15, 2011, and is applied retrospectively. The Company adopted this amendment in the accompanying consolidated financial statements by presenting comprehensive loss in a single continuous statement along with net loss.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In June 2014, the FASB issued Accounting Standards Update (“ASU”) No. 2014-10, <i>Development Stage Entities</i>. The amendments in this guidance remove all incremental financial reporting requirements for development stage entities. Among other changes, this guidance no longer requires development stage entities to present inception-to-date information about income statement line items, cash flows and equity transactions. This guidance is effective for public companies in the first annual period beginning after December 15, 2014. Early application is permitted for interim and annual periods for which financial statements have not yet been issued. The Company early adopted this guidance in the three months ended June 30, 2014 and, as a result, no longer discloses inception-to-date information in its consolidated statements of operations and comprehensive loss, cash flows and stockholders’ deficit and the related notes thereto.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Accounting standards that have been issued or proposed by the FASB or other standards-setting bodies that do not require adoption until a future date are not expected to have a material impact on the Company’s consolidated financial statements upon adoption.</p> </div> </us-gaap:SignificantAccountingPoliciesTextBlock> | |||||||||||||||||||||
| <us-gaap:SubsequentEventsTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_5C441D87-069B-4DFE-A70A-8480D3E3667B_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>15. Subsequent Events</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Issuance of Series E Redeemable Convertible Prefered Stock</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In February 2014, the Company issued 204,101 shares of Series E redeemable convertible preferred stock at an issuance price equal to $2.1725 per share and received gross proceeds of $443. In connection with this financing, the Company paid total issuance costs of $1.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Reverse Stock Split</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> On June 5, 2014, the Company effected a 1-for-6.28 reverse stock split of its issued and outstanding shares of common stock and a proportional adjustment to the existing conversion ratios for each series of Redeemable Preferred Stock (see Note 6). Accordingly, all share and per share amounts for all periods presented in these consolidated financial statements and notes thereto have been adjusted retroactively, where applicable, to reflect this reverse stock split and adjustment of the preferred stock conversion ratios.</p> </div> </us-gaap:SubsequentEventsTextBlock> | |||||||||||||||||||||
| <us-gaap:CommonStockDividendsPerShareDeclared contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="INF" id="id_6893637_4229D595-CBF7-40C3-BC85-F7F0D0408611_1_1" unitRef="iso4217_USD_per_shares"> 0 </us-gaap:CommonStockDividendsPerShareDeclared> | |||||||||||||||||||||
| <us-gaap:DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_E4FAE1B2-75B6-4C4C-BAD4-B467D45B7B5C_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>8. Stock-Based Awards</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt"> <b>2006 Stock Option Plan</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company’s Amended and Restated 2006 Stock Option Plan (the “2006 Plan”) provides for the Company to sell or issue common stock or restricted common stock, or to grant incentive stock options or nonqualified stock options for the purchase of common stock, to employees, members of the board of directors and consultants of the Company. The 2006 Plan is administered by the board of directors, or at the discretion of the board of directors, by a committee of the board. The exercise prices, vesting and other restrictions are determined at the discretion of the board of directors, or their committee if so delegated, except that the exercise price per share of stock options may not be less than 100% of the fair market value of the share of common stock on the date of grant and the term of stock option may not be greater than ten years.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Stock options granted under the 2006 Plan generally vest over four years and expire after ten years, although options have been granted with vesting terms less than four years.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The total number of shares of common stock that may be issued under the 2006 Plan was 1,889,150 shares as of December 31, 2013, of which 371,244 shares remained available for future grant at December 31, 2013.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company generally grants stock-based awards with service conditions only (“service-based” awards).</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As required by the 2006 Plan, the exercise price for stock options granted is not to be less than the fair value of common shares as determined by the Company as of the date of grant. The Company values its common stock by taking into consideration its most recently available valuation of common shares performed by management and the board of directors as well as additional factors which may have changed since the date of the most recent contemporaneous valuation through the date of grant.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 18pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>Stock Option Valuation</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The fair value of each stock option grant is estimated on the date of grant using the Black-Scholes option-pricing model. The Company historically has been a private company and lacks company-specific historical and implied volatility information. Therefore, it estimates its expected stock volatility based on the historical volatility of a publicly traded set of peer companies and expects to continue to do so until such time as it has adequate historical data regarding the volatility of its own traded stock price. The expected term of the Company’s stock options has been determined utilizing the “simplified” method for awards that qualify as “plain-vanilla” options. The expected term of stock options granted to nonemployees is equal to the contractual term of the option award. The risk-free interest rate is determined by reference to the U.S. Treasury yield curve in effect at the time of grant of the award for time periods approximately equal to the expected term of the award. Expected dividend yield is based on the fact that the Company has never paid cash dividends and does not expect to pay any cash dividends in the foreseeable future. The assumptions that the Company used to determine the fair value of the stock options granted to employees and directors are as follows, presented on a weighted average basis (the Company did not grant any stock options to employees or directors during the year ended December 31, 2012):</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="78%"></td> <td valign="bottom" width="9%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="9%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"> <b> Year Ended December 31, </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2011</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Risk-free interest rate</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.41</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.12</td> <td valign="bottom" nowrap="nowrap">% </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Expected term (in years)</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6.25</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6.25</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Expected volatility</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">78</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">85</td> <td valign="bottom" nowrap="nowrap">% </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Expected dividend yield</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0</td> <td valign="bottom" nowrap="nowrap">% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0</td> <td valign="bottom" nowrap="nowrap">% </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The following table summarizes the Company’s stock option activity since January 1, 2011:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="66%"></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Shares Issuable<br /> Under Options</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Weighted<br /> Average<br /> Exercise<br /> Price</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Weighted</b><br /> <b>Average</b><br /> <b>Remaining</b><br /> <b>Contractual</b><br /> <b>Term</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Aggregate<br /> Intrinsic<br /> Value</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center"><b>(In years)</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2"> </td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Outstanding as of January 1, 2011</b></p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">440,301</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.75</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">8.5</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">216</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Granted</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">475,793</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.57</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Exercised</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Forfeited</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Outstanding as of December 31, 2011</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">916,094</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.19</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">8.7</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">354</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Granted</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7,961</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.57</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Exercised</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(16,069</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.88</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Forfeited</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(316,559</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.57</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Outstanding as of December 31, 2012</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">591,427</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.00</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7.1</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">342</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Granted</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">718,903</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">2.64</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Exercised</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Forfeited</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Outstanding as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.88</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7.8</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">10,185</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Options vested and expected to vest as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,310,330</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.88</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">7.8</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">10,185</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Options exercisable as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">657,317</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">1.26</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">6.6</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">5,543</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt; TEXT-INDENT: 4%"> The aggregate intrinsic value of stock options is calculated as the difference between the exercise price of the stock options and the fair value of the Company’s common stock for those stock options that had exercise prices lower than the fair value of the Company’s common stock. The aggregate intrinsic value of stock options exercised was $12 during the year ended December 31, 2012. No stock options were exercised during the years ended December 31, 2011 or 2013.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company received cash proceeds from the exercise of stock options of $13 during the year ended December 31, 2012.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The weighted average grant-date fair value of stock options granted to employees and directors during the years ended December 31, 2011 and 2013 was $1.07 and $1.83 per share, respectively. The Company did not grant stock options to employees or directors in 2012. The grant of stock options in 2012 was to a consultant.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of December 31, 2013, there were outstanding unvested service-based stock options held by nonemployees for the purchase of 17,513 shares of common stock. Additionally as of December 31, 2013, there were outstanding unvested performance-based stock options held by nonemployees for the purchase of 796 shares of common stock.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Restricted Common Stock</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The 2006 Plan provides for the award of restricted stock. The Company has granted restricted common stock with time-based vesting conditions. Unvested shares of restricted common stock may not be sold or transferred by the holder. These restrictions lapse according to the time-based vesting conditions of each award.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The table below summarizes the Company’s restricted stock activity since January 1, 2011:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="79%"></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Shares</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>Weighted<br /> Average Grant-<br /> Date Fair Value</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Unvested restricted common stock as of January 1, 2011</b></p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">38,481</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.82</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Issued</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Vested</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(13,933</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.75</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Forfeited</p> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Unvested restricted common stock as of December 31, 2011</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">24,548</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.82</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Issued</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Vested</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(13,933</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.75</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Forfeited</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Unvested restricted common stock as of December 31, 2012</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">10,615</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.82</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Issued</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Vested</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(3,980</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.75</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 3em; TEXT-INDENT: -1em"> Forfeited</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(6,635</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.82</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> <b>Unvested restricted common stock as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom" nowrap="nowrap" align="right"> — </td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The aggregate intrinsic value of restricted stock awards is calculated as the difference between the <font style="WHITE-SPACE: nowrap">grant-date</font> fair value of the restricted stock awards and the fair value of the Company’s common stock. The aggregate intrinsic value of restricted stock awards that vested during each of the years ended December 31, 2011, 2012 and 2013 was $22, $22 and $38, respectively. As of December 31, 2013, there were no unvested restricted stock awards subject to repurchase.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 18pt; MARGIN-TOP: 0pt"> </p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>Stock-based Compensation</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company recorded stock-based compensation expense related to stock options and restricted common stock in the following expense categories of its statements of operations:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="80%"></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="10" align="center"> <b>Year Ended December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2011 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2012 </b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"> <b> 2013 </b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Research and development</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">30</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">68</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">176</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> General and administrative</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">50</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">53</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">219</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">80</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">121</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">395</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> As of December 31, 2013, the Company had an aggregate of $1,334 of unrecognized stock-based compensation cost, which is expected to be recognized over a weighted average period of 3.6 years.</p> </div> </us-gaap:DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock> | |||||||||||||||||||||
| <us-gaap:EarningsPerShareBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_13" unitRef="iso4217_USD_per_shares"> -19.53 </us-gaap:EarningsPerShareBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_0" unitRef="pure"> -0.340 </us-gaap:EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationTaxCreditsResearch contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_1" unitRef="pure"> -0.090 </us-gaap:EffectiveIncomeTaxRateReconciliationTaxCreditsResearch> | |||||||||||||||||||||
| <us-gaap:ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_5349CC2A-7188-4A86-81D9-C559588DB088_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Impairment of Long-Lived Assets</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Long-lived assets consist of property and equipment. Long-lived assets to be held and used are tested for recoverability whenever events or changes in business circumstances indicate that the carrying amount of the assets may not be fully recoverable. Factors that the Company considers in deciding when to perform an impairment review include significant underperformance of the business in relation to expectations, significant negative industry or economic trends, and significant changes or planned changes in the use of the assets. If an impairment review is performed to evaluate a long-lived asset for recoverability, the Company compares forecasts of undiscounted cash flows expected to result from the use and eventual disposition of the long-lived asset to its carrying value. An impairment loss would be recognized when estimated undiscounted future cash flows expected to result from the use of an asset are less than its carrying amount. The impairment loss would be based on the excess of the carrying value of the impaired asset over its fair value, determined based on discounted cash flows. To date, the Company has not recorded any impairment losses on long-lived assets.</p> </div> </us-gaap:ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_49033173-6B03-42AF-8126-63E7DB4FC084_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 18pt; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <b>Recently Issued and Adopted Accounting Pronouncements</b></p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 6pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In June 2011, the Financial Accounting Standards Board (“FASB”) issued an amendment to the accounting guidance for presentation of comprehensive income. Under the amended guidance, a company may present the total of comprehensive income, the components of net income, and the components of other comprehensive income either in a single continuous statement of comprehensive income or in two separate but consecutive statements. In either case, a company is required to present each component of net income along with total net income, each component of other comprehensive income along with a total for other comprehensive income, and a total amount for comprehensive income. The amendment is effective for fiscal years ending, and interim periods within those years, beginning after December 15, 2011, and is applied retrospectively. The Company adopted this amendment in the accompanying consolidated financial statements by presenting comprehensive loss in a single continuous statement along with net loss.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> In June 2014, the FASB issued Accounting Standards Update (“ASU”) No. 2014-10, <i>Development Stage Entities</i>. The amendments in this guidance remove all incremental financial reporting requirements for development stage entities. Among other changes, this guidance no longer requires development stage entities to present inception-to-date information about income statement line items, cash flows and equity transactions. This guidance is effective for public companies in the first annual period beginning after December 15, 2014. Early application is permitted for interim and annual periods for which financial statements have not yet been issued. The Company early adopted this guidance in the three months ended June 30, 2014 and, as a result, no longer discloses inception-to-date information in its consolidated statements of operations and comprehensive loss, cash flows and stockholders’ deficit and the related notes thereto.</p> <p style="MARGIN-BOTTOM: 0pt; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 10pt 'Times New Roman'; MARGIN-TOP: 12pt; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> Accounting standards that have been issued or proposed by the FASB or other standards-setting bodies that do not require adoption until a future date are not expected to have a material impact on the Company’s consolidated financial statements upon adoption.</p> </div> </us-gaap:NewAccountingPronouncementsPolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:PensionAndOtherPostretirementBenefitsDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_CB72BFB2-0B13-4E68-B54E-5B3FF398038A_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>12. Retirement Plan</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> In 2009, the Company established a Savings Incentive Match Plan for employees. Under the terms of the plan, the Company contributes 2% of an employee’s annual base salary, up to a maximum of the annual Internal Revenue Service compensation limits, for all full-time employees. During the years ended December 31, 2011, 2012 and 2013, the Company recognized $15, $16 and $26, respectively, of expense related to its contributions to this plan.</p> </div> </us-gaap:PensionAndOtherPostretirementBenefitsDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentDisclosureTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_0F7173F2-F9F2-42EE-87C1-F4B7E395E259_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 0pt"> <b>3. Property and Equipment, net</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Property and equipment, net consisted of the following as of December 31, 2012 and 2013:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 12pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="90%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="6" align="center"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 8pt; FONT-FAMILY: Times New Roman"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td style="BORDER-BOTTOM: #000000 1pt solid" valign="bottom" colspan="2" align="center"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Office equipment</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">10</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">27</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Furniture and fixtures</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">44</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">44</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">54</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">71</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"> <td valign="top"> <p style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-LEFT: 1em; TEXT-INDENT: -1em"> Less: Accumulated depreciation</p> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(22</td> <td valign="bottom" nowrap="nowrap">) </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34</td> <td valign="bottom" nowrap="nowrap">) </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 1px solid"> </p> </td> <td> </td> </tr> <tr style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman" bgcolor="#CCEEFF"> <td valign="top"></td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">32</td> <td valign="bottom" nowrap="nowrap"> </td> <td valign="bottom"><font style="FONT-SIZE: 8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">37</td> <td valign="bottom" nowrap="nowrap"> </td> </tr> <tr style="FONT-SIZE: 1px"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td valign="bottom"> <p style="BORDER-TOP: #000000 3px double"> </p> </td> <td> </td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> Depreciation expense was $4, $11 and $12 for the years ended December 31, 2011, 2012 and 2013, respectively.</p> </div> </us-gaap:PropertyPlantAndEquipmentDisclosureTextBlock> | |||||||||||||||||||||
| <us-gaap:SegmentReportingPolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_969AE125-78B4-433A-B43D-BF79E810581A_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Segment Data</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company’s singular focus is on advancing novel therapeutics for patients suffering from severe obesity and obesity-related disorders. No revenue has been generated since inception, and all tangible assets are held in the United States.</p> </div> </us-gaap:SegmentReportingPolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_0B875982-54F3-451C-ABC0-8A3336CE435F_2_2" unitRef="pure"> 0.85 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_139840F9-F679-4D46-951E-289B6DDA6F5E_1_0"> <div> <p style="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> Redeemable Preferred Stock consisted of the following as of December 31, 2012:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="53%"></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Preferred<br /> Shares<br /> Authorized</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Preferred<br /> Shares<br /> Issued and<br /> Outstanding</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Liquidation<br /> Preference</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Carrying<br /> Value</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Common<br /> Stock Issuable<br /> Upon<br /> Conversion</b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series A redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,250</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,222</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">854,018</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series B redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,402</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,335</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6,411,822</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series C redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,161</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,137</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,664,376</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series D redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,011,162</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">11,629,248</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,816</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,091</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1,851,791</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">78,372,931</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">73,991,017</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">63,629</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">62,785</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">11,782,007</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> <p style="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> Redeemable Preferred Stock consisted of the following as of December 31, 2013:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="54%"></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="1%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Preferred<br /> Shares<br /> Authorized</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Preferred<br /> Shares<br /> Issued and<br /> Outstanding</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Liquidation<br /> Preference</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Carrying<br /> Value</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Common<br /> Stock Issuable<br /> Upon<br /> Conversion</b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series A redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">5,363,239</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,250</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">2,229</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">854,018</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series B redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">40,266,246</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,402</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">30,351</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">6,411,822</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series C redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,732,284</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,161</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,144</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,664,376</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series D redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,011,162</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,011,162</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">21,775</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">21,226</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,549,548</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Series E redeemable convertible preferred stock</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">20,919,679</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">16,110,473</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">35,000</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">34,847</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">2,565,361</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">99,292,610</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">94,483,404</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">104,588</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">103,797</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">15,045,125</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> </div> </us-gaap:TemporaryEquityTableTextBlock> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_3_2" unitRef="shares"> 1310330 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:ConcentrationRiskCreditRisk contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_68C6338E-3AEC-47C6-AD17-D602D82552B5_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Concentration of Credit Risk and of Significant Suppliers</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Financial instruments that potentially expose the Company to concentrations of credit risk consist primarily of cash and cash equivalents. The Company has all cash and cash equivalents balances at one accredited financial institution, in amounts that exceed federally insured limits. The Company does not believe that it is subject to unusual credit risk beyond the normal credit risk associated with commercial banking relationships.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company is dependent on third-party manufacturers to supply products for research and development activities in its programs. In particular, the Company relies and expects to continue to rely on a small number of manufacturers to supply it with its requirements for the active pharmaceutical ingredients and formulated drugs related to these programs. These programs could be adversely affected by a significant interruption in the supply of active pharmaceutical ingredients and formulated drugs.</p> </div> </us-gaap:ConcentrationRiskCreditRisk> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_6" unitRef="pure"> 0.041 </us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_3_5" unitRef="pure"> 0.006 </us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost> | |||||||||||||||||||||
| <us-gaap:FairValueMeasurementPolicyPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_4D3C5DD2-337F-4010-9887-18733A603E5B_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Fair Value Measurements</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> Certain assets and liabilities are carried at fair value under GAAP. Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. Financial assets and liabilities carried at fair value are to be classified and disclosed in one of the following three levels of the fair value hierarchy, of which the first two are considered observable and the last is considered unobservable:</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 6pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 1—Quoted prices in active markets for identical assets or liabilities.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 6pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 2—Observable inputs (other than Level 1 quoted prices) such as quoted prices in active markets for similar assets or liabilities, quoted prices in markets that are not active for identical or similar assets or liabilities, or other inputs that are observable or can be corroborated by observable market data.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 6pt; MARGIN-TOP: 0pt"> </p> <table style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; BORDER-COLLAPSE: collapse" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td width="5%"> </td> <td valign="top" width="2%" align="left">•</td> <td valign="top" width="1%"> </td> <td valign="top" align="left">Level 3—Unobservable inputs that are supported by little or no market activity and that are significant to determining the fair value of the assets or liabilities, including pricing models, discounted cash flow methodologies and similar techniques.</td> </tr> </table> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company’s cash equivalents of $8,001 as of December 31, 2012 and $26,501 as of December 31, 2013 were carried at fair value based on quoted prices in active markets, a Level 1 measurement. The carrying values of accounts payable and accrued expenses approximate their fair value due to the short-term nature of these liabilities.</p> </div> </us-gaap:FairValueMeasurementPolicyPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:PropertyPlantAndEquipmentTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_C0A3F102-D4A9-48CA-95DA-ABD96304C5B9_1_0"> <div> <p style="margin-top:6pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> Property and equipment, net consisted of the following as of December 31, 2012 and 2013:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="90%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="6" align="center" style="border-bottom:1.00pt solid #000000"><b>December 31,</b></td> <td valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>2012</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>2013</b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Office equipment</p> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">10</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">27</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Furniture and fixtures</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">44</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">44</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">54</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">71</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Less: Accumulated depreciation</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(22</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(34</td> <td nowrap="nowrap" valign="bottom">) </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"></td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">32</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">37</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> </tr> </table> <p style="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> Depreciation expense was $4, $11 and $12 for the years ended December 31, 2011, 2012 and 2013, respectively.</p> </div> </us-gaap:PropertyPlantAndEquipmentTextBlock> | |||||||||||||||||||||
| <us-gaap:ScheduleOfSharebasedCompensationRestrictedStockAndRestrictedStockUnitsActivityTableTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_67246154-0F61-447E-B567-3AA4C0D2CBD3_1_0"> <div> <p style="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman"> The table below summarizes the Company’s restricted stock activity since January 1, 2011:</p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="100%" border="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" align="center"> <tr> <td width="79%"></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> </tr> <tr style="font-family:Times New Roman; font-size:8pt"> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Shares</b></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" colspan="2" align="center" style="border-bottom:1.00pt solid #000000"><b>Weighted<br /> Average Grant-<br /> Date Fair Value</b></td> <td valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Unvested restricted common stock as of January 1, 2011</b></p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">38,481</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.82</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Issued</p> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Vested</p> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">(13,933</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.75</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Forfeited</p> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"> </td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Unvested restricted common stock as of December 31, 2011</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">24,548</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.82</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Issued</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Vested</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(13,933</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.75</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Forfeited</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Unvested restricted common stock as of December 31, 2012</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">10,615</td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom">$</td> <td valign="bottom" align="right">0.82</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Issued</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Vested</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(3,980</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.75</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:3.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> Forfeited</p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">(6,635</td> <td nowrap="nowrap" valign="bottom">) </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.82</td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td valign="bottom"> <p style="border-top:1.00px solid #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> <tr bgcolor="#CCEEFF" style="font-family:Times New Roman; font-size:10pt"> <td valign="top"> <p style="margin-left:1.00em; text-indent:-1.00em; font-size:10pt; font-family:Times New Roman"> <b>Unvested restricted common stock as of December 31, 2013</b></p> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> <td valign="bottom"><font style="font-size:8pt"> </font></td> <td nowrap="nowrap" valign="bottom"> </td> <td nowrap="nowrap" valign="bottom" align="right"> — </td> <td nowrap="nowrap" valign="bottom"> </td> </tr> <tr style="font-size:1px;"> <td valign="bottom"></td> <td valign="bottom"> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td valign="bottom"> <p style="border-top:3.00px double #000000"> </p> </td> <td> </td> <td valign="bottom"> </td> <td valign="bottom"></td> <td valign="bottom"></td> <td valign="bottom"></td> </tr> </table> </div> </us-gaap:ScheduleOfSharebasedCompensationRestrictedStockAndRestrictedStockUnitsActivityTableTextBlock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationOptionAndIncentivePlansPolicy contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_FACB1E39-490F-4B40-ABB4-981B6B85E6B9_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Accounting for Stock-Based Compensation</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company measures all stock options and other stock-based awards granted to employees and directors at the fair value on the date of the grant using the Black-Scholes option-pricing model. The fair value of the awards is recognized as expense, net of estimated forfeitures, over the requisite service period, which is generally the vesting period of the respective award. The straight-line method of expense recognition is applied to all awards with service-only conditions.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> For stock-based awards granted to consultants and nonemployees, compensation expense is recognized over the period during which services are rendered by such consultants and nonemployees until completed. At the end of each financial reporting period prior to completion of the service, the fair value of these awards is re-measured using the then-current fair value of the Company’s common stock and updated assumption inputs in the Black-Scholes option-pricing model.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company classifies stock-based compensation expense in its consolidated statement of operations and comprehensive loss in the same manner in which the award recipient’s payroll costs are classified or in which the award recipients’ service payments are classified.</p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 12pt; TEXT-INDENT: 4%"> The Company recognizes compensation expense for only the portion of awards that are expected to vest. In developing a forfeiture rate estimate, the Company has considered its historical experience to estimate pre-vesting forfeitures for service-based awards. The impact of a forfeiture rate adjustment will be recognized in full in the period of adjustment, and if the actual forfeiture rate is materially different from the Company’s estimate, the Company may be required to record adjustments to stock-based compensation expense in future periods.</p> </div> </us-gaap:ShareBasedCompensationOptionAndIncentivePlansPolicy> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_23" unitRef="iso4217_USD"> 196000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossUnrealized contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_6" unitRef="iso4217_USD"> -250000 </us-gaap:ForeignCurrencyTransactionGainLossUnrealized> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_9" unitRef="iso4217_USD"> -165000 </us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets> | |||||||||||||||||||||
| <us-gaap:OperatingIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_5" unitRef="iso4217_USD"> -13780000 </us-gaap:OperatingIncomeLoss> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_8" unitRef="iso4217_USD"> -247000 </us-gaap:ForeignCurrencyTransactionGainLossBeforeTax> | |||||||||||||||||||||
| <us-gaap:NonoperatingIncomeExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_9" unitRef="iso4217_USD"> -247000 </us-gaap:NonoperatingIncomeExpense> | |||||||||||||||||||||
| <us-gaap:Revenues contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_0" unitRef="iso4217_USD"> 0 </us-gaap:Revenues> | |||||||||||||||||||||
| <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_15" unitRef="iso4217_USD"> 17000 </us-gaap:PaymentsToAcquirePropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_12" unitRef="iso4217_USD"> -14240000 </us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_10" unitRef="iso4217_USD"> -14027000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_13007_1000042" unitRef="iso4217_USD"> 395000 </us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInIncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_10" unitRef="iso4217_USD"> 1237000 </us-gaap:IncreaseDecreaseInIncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_3" unitRef="iso4217_USD"> 395000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_31" unitRef="iso4217_USD"> 547000 </us-gaap:DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction> | |||||||||||||||||||||
| <us-gaap:OperatingExpenses contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_4" unitRef="iso4217_USD"> 13780000 </us-gaap:OperatingExpenses> | |||||||||||||||||||||
| <us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_F500908E-8A1D-406E-82BE-7F42055522F6_1_0" unitRef="iso4217_USD"> 80000 </us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_2" unitRef="iso4217_USD"> 9561000 </us-gaap:ResearchAndDevelopmentExpense> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_25" unitRef="iso4217_USD"> 25582000 </us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease> | |||||||||||||||||||||
| <us-gaap:ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="INF" id="id_6893637_F0F40E62-6141-49FA-B5B2-37151296BDC8_1_0" unitRef="iso4217_USD"> 0 </us-gaap:ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill> | |||||||||||||||||||||
| <us-gaap:IncomeTaxExpenseBenefit contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_E830BF17-5AE9-4E3E-8EDD-EECE710B648C_3_0" unitRef="iso4217_USD"> 0 </us-gaap:IncomeTaxExpenseBenefit> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesRentExpenseNet contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_974B82A8-83E7-4F80-B0D9-075E5FA84203_3_1" unitRef="iso4217_USD"> 105000 </us-gaap:OperatingLeasesRentExpenseNet> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_11" unitRef="iso4217_USD"> 213000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:Depreciation contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_5" unitRef="iso4217_USD"> 12000 </us-gaap:Depreciation> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_24" unitRef="iso4217_USD"> 40603000 </us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_20" unitRef="iso4217_USD"> 40799000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:DefinedContributionPlanCostRecognized contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_C7F4924D-11EF-4C1E-8378-077C0A46092A_3_0" unitRef="iso4217_USD"> 26000 </us-gaap:DefinedContributionPlanCostRecognized> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccruedLiabilities contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_12" unitRef="iso4217_USD"> -799000 </us-gaap:IncreaseDecreaseInAccruedLiabilities> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_18" unitRef="iso4217_USD"> -17000 </us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:GeneralAndAdministrativeExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_3_3" unitRef="iso4217_USD"> 4219000 </us-gaap:GeneralAndAdministrativeExpense> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccountsPayable contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_3_11" unitRef="iso4217_USD"> 237000 </us-gaap:IncreaseDecreaseInAccountsPayable> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_E66B9C28-78AB-492F-8942-5DB707F6768E_2_0" unitRef="iso4217_USD"> 0 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue> | |||||||||||||||||||||
| <zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_66F4EEEC-CBFE-4D68-A9FF-EDCE90D09D7C_1_0" unitRef="pure"> 0.70 </zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion> | |||||||||||||||||||||
| <zfgn:EffectiveIncomeTaxRateReconciliationTaxRefundsRelatedToResearchAndDevelopment contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_3D751ABB-5B7F-470D-B22C-F991EB0F32AE_2_0" unitRef="pure"> 0.45 </zfgn:EffectiveIncomeTaxRateReconciliationTaxRefundsRelatedToResearchAndDevelopment> | |||||||||||||||||||||
| <zfgn:LikelihoodPercentageMinimum contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="INF" id="id_6893637_3E124F34-2A35-4BC2-B1BC-E42A07745939_1_0" unitRef="pure"> 0.50 </zfgn:LikelihoodPercentageMinimum> | |||||||||||||||||||||
| <zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountDecrease contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_3_1" unitRef="iso4217_USD"> 0 </zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountDecrease> | |||||||||||||||||||||
| <zfgn:DebtInstrumentConvertibleStockPriceTriggerPercentage contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="2" id="id_6893637_774955CB-9842-4BE3-917D-4AC1714BA884_3_3" unitRef="pure"> 0.90 </zfgn:DebtInstrumentConvertibleStockPriceTriggerPercentage> | |||||||||||||||||||||
| <zfgn:ShortTermInvestmentMaturityPeriodDescription contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_E86F86FE-5F88-4725-9B03-C6D8A65D50FC_1_0"> Ninety days or less </zfgn:ShortTermInvestmentMaturityPeriodDescription> | |||||||||||||||||||||
| <zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountIncrease contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_3_2" unitRef="iso4217_USD"> 6351000 </zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountIncrease> | |||||||||||||||||||||
| <zfgn:NumberOfVotesPerCommonShare contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" decimals="INF" id="id_6893637_4229D595-CBF7-40C3-BC85-F7F0D0408611_1_0" unitRef="Vote"> 1 </zfgn:NumberOfVotesPerCommonShare> | |||||||||||||||||||||
| <zfgn:ResearchContractCostsAndAccrualsPolicyTextBlock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0" id="id_6893637_29944271-34A4-441E-9AFB-DAB96DA90FC6_1_0"> <div> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 18pt"> <b>Research Contract Costs and Accruals</b></p> <p style="MARGIN-BOTTOM: 0pt; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; MARGIN-TOP: 6pt; TEXT-INDENT: 4%"> The Company has entered into various research and development contracts with research institutions and other companies both inside and outside of the United States. These agreements are generally cancelable, and related payments are recorded as research and development expenses as incurred. The Company records accruals for estimated ongoing research costs. When evaluating the adequacy of the accrued liabilities, the Company analyzes progress of the studies, including the phase or completion of events, invoices received and contracted costs. Significant judgments and estimates are made in determining the accrued balances at the end of any reporting period. Actual results could differ from the Company’s estimates. The Company’s historical accrual estimates have not been materially different from the actual costs.</p> </div> </zfgn:ResearchContractCostsAndAccrualsPolicyTextBlock> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1268687x1281225" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_1003_0" unitRef="shares"> 1310330 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceInitialPublicOffering contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1269523x1275948" decimals="-3" id="id_6893637_4D36D563-9B77-4D96-AFFE-6CF70E56D42C_1001_0" unitRef="iso4217_USD"> 35000000 </us-gaap:ProceedsFromIssuanceInitialPublicOffering> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1269523x1275948_1280964x1382801" id="id_6893637_FB4D2C7C-17CF-4D54-A778-489F7BE10089_1001_1"> P10Y </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfPreferredStockAndPreferenceStock contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1269523x1277596" decimals="-3" id="id_6893637_774955CB-9842-4BE3-917D-4AC1714BA884_1003_2" unitRef="iso4217_USD"> 10000000 </us-gaap:ProceedsFromIssuanceOfPreferredStockAndPreferenceStock> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_9001_12" unitRef="shares"> 6635 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210" decimals="0" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_9001_10" unitRef="iso4217_USD_per_shares"> 0 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_9001_11" unitRef="shares"> 3980 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_9001_10" unitRef="shares"> 0 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210" decimals="2" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_9001_11" unitRef="iso4217_USD_per_shares"> 0.75 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210" decimals="2" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_9001_12" unitRef="iso4217_USD_per_shares"> 0.82 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210" decimals="-3" id="id_6893637_AFC756F7-662B-4340-BD86-CFE20DAC72C3_1003_0" unitRef="iso4217_USD"> 38000 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested> | |||||||||||||||||||||
| <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210_1276401x1270422" decimals="INF" id="id_6893637_3F895A16-4BEF-4EDF-91E1-1A4D56B18D46_1001_0" unitRef="shares"> 6635 </us-gaap:StockRepurchasedAndRetiredDuringPeriodShares> | |||||||||||||||||||||
| <zfgn:PercentageReductionResearchAndDevelopmentCosts contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273333x1281276" decimals="2" id="id_6893637_D603F107-BDB3-43A7-98F8-16612F0F7189_1001_2" unitRef="pure"> 0.45 </zfgn:PercentageReductionResearchAndDevelopmentCosts> | |||||||||||||||||||||
| <us-gaap:LeaseExpirationDate1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273383x1541820" id="id_6893637_F017FF3B-D60E-4EEF-A6CF-3209BF6EFA93_1001_2"> 2014-07-31 </us-gaap:LeaseExpirationDate1> | |||||||||||||||||||||
| <zfgn:OperatingLeaseOptionForExtensionPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273383x1541820" id="id_6893637_F017FF3B-D60E-4EEF-A6CF-3209BF6EFA93_1001_3"> P6M </zfgn:OperatingLeaseOptionForExtensionPeriod> | |||||||||||||||||||||
| <us-gaap:LeaseExpirationDate1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273383x1541820_1557349x1292095" id="id_6893637_F017FF3B-D60E-4EEF-A6CF-3209BF6EFA93_2001_1"> 2014-01-31 </us-gaap:LeaseExpirationDate1> | |||||||||||||||||||||
| <us-gaap:LeaseExpirationDate1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273383x1541820_1557349x1543948" id="id_6893637_F017FF3B-D60E-4EEF-A6CF-3209BF6EFA93_3001_0"> 2013-07-31 </us-gaap:LeaseExpirationDate1> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1274159x1269133" decimals="-3" id="id_6893637_7C9FE533-0621-4211-BBE5-4EDB4B3FA109_1003_1" unitRef="iso4217_USD"> 219000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1274159x1269570" decimals="-3" id="id_6893637_7C9FE533-0621-4211-BBE5-4EDB4B3FA109_2003_0" unitRef="iso4217_USD"> 176000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1269676" decimals="2" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_1001_7" unitRef="pure"> 0.70 </zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1271310" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_14007_1000040" unitRef="iso4217_USD"> 156000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1271310_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_14001_400039" unitRef="shares"> 16110473 </us-gaap:StockIssuedDuringPeriodSharesNewIssues> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1271310_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_14001_500038" unitRef="iso4217_USD"> 34844000 </us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues> | |||||||||||||||||||||
| <us-gaap:ConvertiblePreferredStockTermsOfConversion contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1274527" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_2001_1"> Each share of Redeemable Preferred Stock is convertible into common stock at the option of the stockholder at any time after the date of issuance. Each share of the preferred stock will automatically be converted into shares of common stock, at the applicable Series A, Series B, Series C, Series D and Series E redeemable convertible preferred stock conversion ratio then in effect, upon a qualified public offering with net proceeds of not less than $35,000. </us-gaap:ConvertiblePreferredStockTermsOfConversion> | |||||||||||||||||||||
| <us-gaap:PreferredStockRedemptionDate contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1274527" id="id_6893637_E448C464-0661-4592-9952-B386A592F1D9_1001_1"> 2017-11-22 </us-gaap:PreferredStockRedemptionDate> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceInitialPublicOffering contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1274527" decimals="-3" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_2001_0" unitRef="iso4217_USD"> 35000000 </us-gaap:ProceedsFromIssuanceInitialPublicOffering> | |||||||||||||||||||||
| <zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1274527" decimals="2" id="id_6893637_E448C464-0661-4592-9952-B386A592F1D9_1001_0" unitRef="pure"> 0.70 </zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion> | |||||||||||||||||||||
| <zfgn:NumberOfAnnualInstallment contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1274527" decimals="INF" id="id_6893637_E448C464-0661-4592-9952-B386A592F1D9_1001_2" unitRef="Installment"> 3 </zfgn:NumberOfAnnualInstallment> | |||||||||||||||||||||
| <zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1279561" decimals="2" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_3001_9" unitRef="pure"> 0.70 </zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion> | |||||||||||||||||||||
| <zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281157" decimals="2" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_4001_8" unitRef="pure"> 0.70 </zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281158" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_15007_1000037" unitRef="iso4217_USD"> 1000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281158" decimals="2" id="id_6893637_83B57A0B-AB98-4077-B6FD-E82C6DFF9A0D_5001_10" unitRef="pure"> 0.65 </zfgn:PercentageOfOutstandingPreferredShareholdersVoteRequiredForConversion> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281158_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_15001_400036" unitRef="shares"> 4381914 </us-gaap:StockIssuedDuringPeriodSharesNewIssues> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281158_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_15001_500035" unitRef="iso4217_USD"> 5955000 </us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1269588" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_13006_900044" unitRef="iso4217_USD"> -14027000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:StockRepurchasedAndRetiredDuringPeriodShares contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1270422" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_13003_600041" unitRef="shares"> -6635 </us-gaap:StockRepurchasedAndRetiredDuringPeriodShares> | |||||||||||||||||||||
| <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_13005_800042" unitRef="iso4217_USD"> 395000 </us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_13005_800043" unitRef="iso4217_USD"> 213000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_13001_500043" unitRef="iso4217_USD"> -213000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <zfgn:TaxCreditCarryForwardExpirationYearStart contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1276398" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_1001_8"> 2021 </zfgn:TaxCreditCarryForwardExpirationYearStart> | |||||||||||||||||||||
| <zfgn:NetOperatingLossCarryForwardExpirationYearBegin contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1276398" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_1001_3"> 2014 </zfgn:NetOperatingLossCarryForwardExpirationYearBegin> | |||||||||||||||||||||
| <zfgn:TaxCreditCarryForwardExpirationYearStart contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1280458" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_2001_7"> 2026 </zfgn:TaxCreditCarryForwardExpirationYearStart> | |||||||||||||||||||||
| <zfgn:NetOperatingLossCarryForwardExpirationYearBegin contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1280458" id="id_6893637_49281878-EDA1-4973-B405-3ACD88F70402_2001_2"> 2026 </zfgn:NetOperatingLossCarryForwardExpirationYearBegin> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossUnrealized contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1574427" decimals="-3" id="id_6893637_D603F107-BDB3-43A7-98F8-16612F0F7189_2001_0" unitRef="iso4217_USD"> -250000 </us-gaap:ForeignCurrencyTransactionGainLossUnrealized> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280964x1382801" id="id_6893637_29C27DEF-FF72-43EA-A2E6-E5B33DC56617_1001_1"> P10Y </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280964x1382801" decimals="INF" id="id_6893637_FB4D2C7C-17CF-4D54-A778-489F7BE10089_2001_0" unitRef="pure"> 1.00 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1 contextRef="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280964x1382801" id="id_6893637_29C27DEF-FF72-43EA-A2E6-E5B33DC56617_1001_0"> P4Y </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_6001_7" unitRef="shares"> 7961 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_6001_8" unitRef="iso4217_USD_per_shares"> 0.88 </us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="2" id="id_6893637_780167DC-C6E5-48FF-BF9F-B248C8D82D10_2_0" unitRef="iso4217_USD_per_shares"> 0.00 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_2_8" unitRef="pure"> 0.000 </us-gaap:EffectiveIncomeTaxRateContinuingOperations> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_13" unitRef="iso4217_USD"> -13589000 </us-gaap:NetCashProvidedByUsedInOperatingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_6001_9" unitRef="shares"> 316559 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_2_3" unitRef="pure"> -0.050 </us-gaap:EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes> | |||||||||||||||||||||
| <us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="0" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_14" unitRef="shares"> 709678 </us-gaap:WeightedAverageNumberOfShareOutstandingBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_2_7" unitRef="pure"> 0.382 </us-gaap:EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2 contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" id="id_6893637_B27D47F3-E181-4656-870C-C8832CFB79CA_3001_4"> P7Y1M6D </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_6001_9" unitRef="iso4217_USD_per_shares"> 1.57 </us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="2" id="id_6893637_B0CAB224-B515-4354-8937-EF56DCFC2769_6001_7" unitRef="iso4217_USD_per_shares"> 1.57 </us-gaap:ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice> | |||||||||||||||||||||
| <us-gaap:EarningsPerShareBasicAndDiluted contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="2" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_13" unitRef="iso4217_USD_per_shares"> -19.65 </us-gaap:EarningsPerShareBasicAndDiluted> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_2_0" unitRef="pure"> -0.340 </us-gaap:EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationTaxCreditsResearch contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_2_1" unitRef="pure"> -0.012 </us-gaap:EffectiveIncomeTaxRateReconciliationTaxCreditsResearch> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_2_2" unitRef="shares"> 602042 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_2_6" unitRef="pure"> 0.018 </us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment> | |||||||||||||||||||||
| <us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="3" id="id_6893637_1EB433E2-7325-4057-B978-16F3F2BE011E_2_5" unitRef="pure"> 0.002 </us-gaap:EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="INF" id="id_6893637_0336EB64-731C-48CA-83A2-CF1366C81D8E_6001_8" unitRef="shares"> 16069 </us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_9" unitRef="iso4217_USD"> 269000 </us-gaap:IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8007_1000026" unitRef="iso4217_USD"> 13000 </us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised> | |||||||||||||||||||||
| <us-gaap:OperatingIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_5" unitRef="iso4217_USD"> -13791000 </us-gaap:OperatingIncomeLoss> | |||||||||||||||||||||
| <us-gaap:ForeignCurrencyTransactionGainLossBeforeTax contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_8" unitRef="iso4217_USD"> 8000 </us-gaap:ForeignCurrencyTransactionGainLossBeforeTax> | |||||||||||||||||||||
| <us-gaap:RelatedPartyTransactionOtherRevenuesFromTransactionsWithRelatedParty contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_F500908E-8A1D-406E-82BE-7F42055522F6_2_1" unitRef="iso4217_USD"> 500000 </us-gaap:RelatedPartyTransactionOtherRevenuesFromTransactionsWithRelatedParty> | |||||||||||||||||||||
| <us-gaap:NonoperatingIncomeExpense contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_9" unitRef="iso4217_USD"> -89000 </us-gaap:NonoperatingIncomeExpense> | |||||||||||||||||||||
| <us-gaap:Revenues contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_0" unitRef="iso4217_USD"> 0 </us-gaap:Revenues> | |||||||||||||||||||||
| <us-gaap:PaymentsToAcquirePropertyPlantAndEquipment contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_15" unitRef="iso4217_USD"> 2000 </us-gaap:PaymentsToAcquirePropertyPlantAndEquipment> | |||||||||||||||||||||
| <us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_12" unitRef="iso4217_USD"> -13947000 </us-gaap:NetIncomeLossAvailableToCommonStockholdersBasic> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_10" unitRef="iso4217_USD"> -13880000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8007_1000028" unitRef="iso4217_USD"> 121000 </us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInIncomeTaxesReceivable contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_10" unitRef="iso4217_USD"> 630000 </us-gaap:IncreaseDecreaseInIncomeTaxesReceivable> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_3" unitRef="iso4217_USD"> 121000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:InterestExpense contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_7" unitRef="iso4217_USD"> 97000 </us-gaap:InterestExpense> | |||||||||||||||||||||
| <us-gaap:OperatingExpenses contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_4" unitRef="iso4217_USD"> 13791000 </us-gaap:OperatingExpenses> | |||||||||||||||||||||
| <us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_F500908E-8A1D-406E-82BE-7F42055522F6_2_0" unitRef="iso4217_USD"> 80000 </us-gaap:RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty> | |||||||||||||||||||||
| <us-gaap:ResearchAndDevelopmentExpense contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_2" unitRef="iso4217_USD"> 11544000 </us-gaap:ResearchAndDevelopmentExpense> | |||||||||||||||||||||
| <us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_25" unitRef="iso4217_USD"> 8468000 </us-gaap:CashAndCashEquivalentsPeriodIncreaseDecrease> | |||||||||||||||||||||
| <us-gaap:CostOfServicesLicensesAndMaintenanceAgreements contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5682BFB1-C190-4F15-AA03-07ABAFB9AC0A_2_0" unitRef="iso4217_USD"> 150000 </us-gaap:CostOfServicesLicensesAndMaintenanceAgreements> | |||||||||||||||||||||
| <us-gaap:IncomeTaxExpenseBenefit contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_E830BF17-5AE9-4E3E-8EDD-EECE710B648C_2_0" unitRef="iso4217_USD"> 0 </us-gaap:IncomeTaxExpenseBenefit> | |||||||||||||||||||||
| <us-gaap:OperatingLeasesRentExpenseNet contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_974B82A8-83E7-4F80-B0D9-075E5FA84203_2_1" unitRef="iso4217_USD"> 129000 </us-gaap:OperatingLeasesRentExpenseNet> | |||||||||||||||||||||
| <us-gaap:ProceedsFromNotesPayable contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_21" unitRef="iso4217_USD"> 5989000 </us-gaap:ProceedsFromNotesPayable> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_11" unitRef="iso4217_USD"> 67000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:Depreciation contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_5" unitRef="iso4217_USD"> 11000 </us-gaap:Depreciation> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_24" unitRef="iso4217_USD"> 22059000 </us-gaap:NetCashProvidedByUsedInFinancingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfCommonStock contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_22" unitRef="iso4217_USD"> 13000 </us-gaap:ProceedsFromIssuanceOfCommonStock> | |||||||||||||||||||||
| <us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_20" unitRef="iso4217_USD"> 16057000 </us-gaap:ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock> | |||||||||||||||||||||
| <us-gaap:ConversionOfStockAmountConverted1 contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_30" unitRef="iso4217_USD"> 6086000 </us-gaap:ConversionOfStockAmountConverted1> | |||||||||||||||||||||
| <us-gaap:DefinedContributionPlanCostRecognized contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_C7F4924D-11EF-4C1E-8378-077C0A46092A_2_0" unitRef="iso4217_USD"> 16000 </us-gaap:DefinedContributionPlanCostRecognized> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccruedLiabilities contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_12" unitRef="iso4217_USD"> 234000 </us-gaap:IncreaseDecreaseInAccruedLiabilities> | |||||||||||||||||||||
| <us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_18" unitRef="iso4217_USD"> -2000 </us-gaap:NetCashProvidedByUsedInInvestingActivitiesContinuingOperations> | |||||||||||||||||||||
| <us-gaap:ProceedsFromStockOptionsExercised contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_3A1B644C-E879-4BED-AE84-D46DEE8034AC_1_0" unitRef="iso4217_USD"> 13000 </us-gaap:ProceedsFromStockOptionsExercised> | |||||||||||||||||||||
| <us-gaap:PaidInKindInterest contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_4" unitRef="iso4217_USD"> 97000 </us-gaap:PaidInKindInterest> | |||||||||||||||||||||
| <us-gaap:GeneralAndAdministrativeExpense contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_5C695E1A-3607-4DE7-A9EF-BDAA542B5C38_2_3" unitRef="iso4217_USD"> 2247000 </us-gaap:GeneralAndAdministrativeExpense> | |||||||||||||||||||||
| <us-gaap:IncreaseDecreaseInAccountsPayable contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_8F3CD57A-98DD-433C-ADE8-2B6FAB8862EA_2_11" unitRef="iso4217_USD"> 727000 </us-gaap:IncreaseDecreaseInAccountsPayable> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_E66B9C28-78AB-492F-8942-5DB707F6768E_3_0" unitRef="iso4217_USD"> 12000 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue> | |||||||||||||||||||||
| <zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountDecrease contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_2_1" unitRef="iso4217_USD"> 0 </zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountDecrease> | |||||||||||||||||||||
| <zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountIncrease contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0" decimals="-3" id="id_6893637_40BCCCF3-3017-4966-85CB-EEB71395F0CA_2_2" unitRef="iso4217_USD"> 5262000 </zfgn:ValuationAllowanceDeferredTaxAssetChangeInAmountIncrease> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1268687x1281225" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_1002_0" unitRef="shares"> 591427 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1268687x1487477" decimals="INF" id="id_6893637_65D38462-D34F-44A2-8264-D2F91B8526BA_2002_1" unitRef="shares"> 10615 </us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1270313x1271210" decimals="0" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_6001_6" unitRef="iso4217_USD_per_shares"> 0 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_6001_7" unitRef="shares"> 13933 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1270313x1271210" decimals="INF" id="id_6893637_33142EC4-D97C-43F1-AE4B-5B2BA2CC924B_6001_6" unitRef="shares"> 0 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod> | |||||||||||||||||||||
| <us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1270313x1271210" decimals="2" id="id_6893637_3DD93B1B-B6D1-4F93-9A55-393622157A11_6001_7" unitRef="iso4217_USD_per_shares"> 0.75 </us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue> | |||||||||||||||||||||
| <us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1270313x1271210" decimals="-3" id="id_6893637_AFC756F7-662B-4340-BD86-CFE20DAC72C3_1002_0" unitRef="iso4217_USD"> 22000 </us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1274159x1269133" decimals="-3" id="id_6893637_7C9FE533-0621-4211-BBE5-4EDB4B3FA109_1002_1" unitRef="iso4217_USD"> 53000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:AllocatedShareBasedCompensationExpense contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1274159x1269570" decimals="-3" id="id_6893637_7C9FE533-0621-4211-BBE5-4EDB4B3FA109_2002_0" unitRef="iso4217_USD"> 68000 </us-gaap:AllocatedShareBasedCompensationExpense> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1279561" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_9007_1000020" unitRef="iso4217_USD"> 8000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesNewIssues contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1279561_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_9001_400019" unitRef="shares"> 7808400 </us-gaap:StockIssuedDuringPeriodSharesNewIssues> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1279561_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_9001_500018" unitRef="iso4217_USD"> 7067000 </us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues> | |||||||||||||||||||||
| <us-gaap:PaymentsOfStockIssuanceCosts contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1281158" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_10007_1000023" unitRef="iso4217_USD"> 54000 </us-gaap:PaymentsOfStockIssuanceCosts> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesNewIssues contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1281158_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_10001_400022" unitRef="shares"> 6653988 </us-gaap:StockIssuedDuringPeriodSharesNewIssues> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1281158_1276401x1276186" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_10001_400025" unitRef="shares"> 4975260 </us-gaap:StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodValueConversionOfConvertibleSecuritiesNetOfAdjustments contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1281158_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_10001_500024" unitRef="iso4217_USD"> 6086000 </us-gaap:StockIssuedDuringPeriodValueConversionOfConvertibleSecuritiesNetOfAdjustments> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1281158_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_10001_500021" unitRef="iso4217_USD"> 8990000 </us-gaap:TemporaryEquityStockIssuedDuringPeriodValueNewIssues> | |||||||||||||||||||||
| <us-gaap:NetIncomeLoss contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1269588" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8006_900030" unitRef="iso4217_USD"> -13880000 </us-gaap:NetIncomeLoss> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1270422" decimals="INF" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8003_600027" unitRef="shares"> 16069 </us-gaap:StockIssuedDuringPeriodSharesStockOptionsExercised> | |||||||||||||||||||||
| <us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8005_800026" unitRef="iso4217_USD"> 13000 </us-gaap:StockIssuedDuringPeriodValueStockOptionsExercised> | |||||||||||||||||||||
| <us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8005_800028" unitRef="iso4217_USD"> 121000 </us-gaap:AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1273630" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8005_800029" unitRef="iso4217_USD"> 67000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment contextRef="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1276186" decimals="-3" id="id_6893637_1AE1D69A-9B78-4DAC-9C40-6490FC851C6C_8001_500029" unitRef="iso4217_USD"> -67000 </us-gaap:TemporaryEquityAccretionToRedemptionValueAdjustment> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
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| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
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| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1273630"> | |||||||||||||||||||||
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| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:AdditionalPaidInCapitalMember </xbrldi:explicitMember> | |||||||||||||||||||||
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| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276401x1270422"> | |||||||||||||||||||||
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| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
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| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
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| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1279561_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1274159x1269570"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:ResearchAndDevelopmentExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1274159x1269133"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:GeneralAndAdministrativeExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1270313x1271210"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1268687x1487477"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> zfgn:UnvestedRestrictedCommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0_1268687x1281225"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> us-gaap:StockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_366_20121231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280964x1382801"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandSixStockOptionPlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1574427"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis"> zfgn:TaxIncentiveMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1280458"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis"> us-gaap:DomesticCountryMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1280651x1276398"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis"> us-gaap:StateAndLocalJurisdictionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1273630"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:AdditionalPaidInCapitalMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276401x1269588"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RetainedEarningsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281158_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1281157"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesBPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1274527"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:RedeemablePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1271310_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesEPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1271310"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesEPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1276400x1269676"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesAPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
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| <entity> | |||||||||||||||||||||
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| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:GeneralAndAdministrativeExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
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| </entity> | |||||||||||||||||||||
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| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273383x1541820_1557349x1543948"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="zfgn:ScheduleOfOperatingLeasesAxis"> zfgn:BeforeAmendmentMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:TitleOfIndividualAxis"> zfgn:OfficeSpaceMember </xbrldi:explicitMember> | |||||||||||||||||||||
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| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
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| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="zfgn:ScheduleOfOperatingLeasesAxis"> zfgn:AfterAmendmentMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:TitleOfIndividualAxis"> zfgn:OfficeSpaceMember </xbrldi:explicitMember> | |||||||||||||||||||||
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| </entity> | |||||||||||||||||||||
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| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273383x1541820"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:TitleOfIndividualAxis"> zfgn:OfficeSpaceMember </xbrldi:explicitMember> | |||||||||||||||||||||
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| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1273333x1281276"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementGeographicalAxis"> country:AU </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1270313x1271210"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1269523x1277596"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:RangeAxis"> us-gaap:MinimumMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1269523x1275948_1280964x1382801"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandSixStockOptionPlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:RangeAxis"> us-gaap:MaximumMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1269523x1275948"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:RangeAxis"> us-gaap:MaximumMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0_1268687x1281225"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> us-gaap:StockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20131231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276401x1273630"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:AdditionalPaidInCapitalMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276401x1269588"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RetainedEarningsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1281157_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesBPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1281157"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesBPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1279561_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1274159x1269570"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:ResearchAndDevelopmentExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1274159x1269133"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:GeneralAndAdministrativeExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1270313x1271210"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1268687x1487477"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> zfgn:UnvestedRestrictedCommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0_1268687x1281225"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> us-gaap:StockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20111231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2011-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2011-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_365_20101231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2010-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2010-12-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_31_20130131_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-01-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_30_20131130_0_1276400x1271310"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesEPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-11-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-11-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_30_20121130_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-11-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-11-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_29_20120229_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2012-02-01 </startDate> | |||||||||||||||||||||
| <endDate> 2012-02-29 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_28_20140228_0_1271378x1273350_1276400x1271310"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesEPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis"> us-gaap:SubsequentEventMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-02-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-02-28 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1280964x1382801"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandSixStockOptionPlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1280964x1371249"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandFourteenStockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1280651x1574427"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis"> zfgn:TaxIncentiveMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760_1280323x1450314_1280806x1591559"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanAMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:MajorTypesOfDebtAndEquitySecuritiesAxis"> zfgn:DebtDiscountAndFinanceCostsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760_1280323x1450314"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanAMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1275460x1336760"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1274159x1269570"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:ResearchAndDevelopmentExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1274159x1269133"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:GeneralAndAdministrativeExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1273383x1591562"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:TitleOfIndividualAxis"> zfgn:OfficeTwoMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1273334x1272538_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementScenarioAxis"> us-gaap:IPOMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1273333x1281276"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementGeographicalAxis"> country:AU </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1270313x1494998"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> zfgn:ConsultantMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1270313x1275629"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:EmployeeStockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1269523x1275948_1280964x1382801"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandSixStockOptionPlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:RangeAxis"> us-gaap:MaximumMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0_1268687x1281225"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> us-gaap:StockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20140930_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20130930_0_1280651x1574427"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis"> zfgn:TaxIncentiveMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20130930_0_1274159x1269570"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:ResearchAndDevelopmentExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20130930_0_1274159x1269133"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeStatementLocationAxis"> us-gaap:GeneralAndAdministrativeExpenseMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20130930_0_1270313x1271210_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20130930_0_1268687x1281225"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> us-gaap:StockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20130930_0_1268687x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_273_20130930_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2013-01-01 </startDate> | |||||||||||||||||||||
| <endDate> 2013-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_1_20140930_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-09-30 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-30 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_1_20140901_0_1280964x1412684"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandAndFourteenEmployeeStockPurchasePlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-09-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-01 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_1_20140901_0_1269523x1275948_1280964x1412684"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandAndFourteenEmployeeStockPurchasePlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:RangeAxis"> us-gaap:MaximumMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-09-01 </startDate> | |||||||||||||||||||||
| <endDate> 2014-09-01 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_1_20140624_0_1273334x1272538_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementScenarioAxis"> us-gaap:IPOMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-06-24 </startDate> | |||||||||||||||||||||
| <endDate> 2014-06-24 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_1_20140605_0_1271378x1273350"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis"> us-gaap:SubsequentEventMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-06-05 </startDate> | |||||||||||||||||||||
| <endDate> 2014-06-05 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_1_20140331_0_1275460x1336760_1280323x1450314"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanAMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-03-31 </startDate> | |||||||||||||||||||||
| <endDate> 2014-03-31 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_1_20140515_0_1273383x1591562"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:TitleOfIndividualAxis"> zfgn:OfficeTwoMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <startDate> 2014-05-15 </startDate> | |||||||||||||||||||||
| <endDate> 2014-05-15 </endDate> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1281195x1275455"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:ShortTermDebtTypeAxis"> us-gaap:ConvertibleNotesPayableMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280964x1382801"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandSixStockOptionPlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280651x1280458"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis"> us-gaap:DomesticCountryMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1280651x1276398"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:IncomeTaxAuthorityAxis"> us-gaap:StateAndLocalJurisdictionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1273630"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:AdditionalPaidInCapitalMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276401x1269588"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RetainedEarningsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1281157"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesBPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
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| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1271310"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesEPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276400x1269676"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesAPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276136x1509307"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PropertyPlantAndEquipmentByTypeAxis"> zfgn:OfficeAndLaboratorySpaceMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276136x1279264"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PropertyPlantAndEquipmentByTypeAxis"> us-gaap:OfficeEquipmentMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
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| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1276136x1274094"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PropertyPlantAndEquipmentByTypeAxis"> us-gaap:FurnitureAndFixturesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1273333x1281276"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementGeographicalAxis"> country:AU </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1272610x1574446"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:LongTermPurchaseCommitmentByCategoryOfItemPurchasedAxis"> zfgn:SubsequentLicensedProductMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1272610x1574445"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:LongTermPurchaseCommitmentByCategoryOfItemPurchasedAxis"> zfgn:ProductCommercializationMilestonesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1272610x1574444"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:LongTermPurchaseCommitmentByCategoryOfItemPurchasedAxis"> zfgn:PreCommercializationMilestonesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1270313x1384152"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> zfgn:ServiceBasedAwardsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1270313x1274447"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:PerformanceSharesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0_1269038x1272304"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis"> us-gaap:FairValueInputsLevel1Member </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1273630"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:AdditionalPaidInCapitalMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276401x1269588"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RetainedEarningsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1281157"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesBPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276400x1269676"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesAPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276136x1279264"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PropertyPlantAndEquipmentByTypeAxis"> us-gaap:OfficeEquipmentMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1276136x1274094"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PropertyPlantAndEquipmentByTypeAxis"> us-gaap:FurnitureAndFixturesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1273333x1281276"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementGeographicalAxis"> country:AU </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1270313x1271210"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0_1269038x1272304"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis"> us-gaap:FairValueInputsLevel1Member </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2011-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1273630"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:AdditionalPaidInCapitalMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2011-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2011-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276401x1269588"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RetainedEarningsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2011-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20111231_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2011-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20111231_0_1270313x1271210"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2011-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20111231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2011-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1276186"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RedeemableConvertiblePreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2010-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1273630"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:AdditionalPaidInCapitalMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2010-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2010-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20101231_0_1276401x1269588"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:RetainedEarningsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2010-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20101231_0_1270313x1271210"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> us-gaap:RestrictedStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2010-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20101231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2010-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20091231_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2009-12-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280964x1412684"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandAndFourteenEmployeeStockPurchasePlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280964x1382801"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandSixStockOptionPlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280964x1371249"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandFourteenStockOptionMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1280323x1450314"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanAMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1275460x1336760_1280323x1546828"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanBMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1275460x1336760"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1273334x1574584_1275460x1336760_1280323x1305126"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanCMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementScenarioAxis"> zfgn:QualifiedIpoMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1273334x1272538_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementScenarioAxis"> us-gaap:IPOMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1273333x1281276"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementGeographicalAxis"> country:AU </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1574446"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:LongTermPurchaseCommitmentByCategoryOfItemPurchasedAxis"> zfgn:SubsequentLicensedProductMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1574445"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:LongTermPurchaseCommitmentByCategoryOfItemPurchasedAxis"> zfgn:ProductCommercializationMilestonesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1574444"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:LongTermPurchaseCommitmentByCategoryOfItemPurchasedAxis"> zfgn:PreCommercializationMilestonesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1272610x1518235"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:LongTermPurchaseCommitmentByCategoryOfItemPurchasedAxis"> zfgn:DevelopmentBasedMilestonesMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1270313x1591560"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> zfgn:NonemployeeServiceBasedOptionsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1270313x1575866"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:AwardTypeAxis"> zfgn:NonemployeePerformanceBasedOptionsMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0_1269038x1272304"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:FairValueByFairValueHierarchyLevelAxis"> us-gaap:FairValueInputsLevel1Member </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140930_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20130930_0"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-09-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20120831_0_1281195x1275455"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:ShortTermDebtTypeAxis"> us-gaap:ConvertibleNotesPayableMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-08-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140624_0_1273334x1272538_1276401x1270422"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementEquityComponentsAxis"> us-gaap:CommonStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementScenarioAxis"> us-gaap:IPOMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-06-24 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140605_0_1280964x1412684"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:PlanNameAxis"> zfgn:TwoThousandAndFourteenEmployeeStockPurchasePlanMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-06-05 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140331_0_1275460x1336760_1280323x1450314"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanAMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-03-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140331_0_1275460x1336760_1280323x1313904"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:DebtInstrumentAxis"> zfgn:TermLoanBAndCMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-03-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140331_0_1275460x1336760"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:CreditFacilityAxis"> zfgn:CreditFacilityMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-03-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20120229_0_1276400x1279561"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesCPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-02-29 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20140228_0_1271378x1273350_1276400x1271310"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesEPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:SubsequentEventTypeAxis"> us-gaap:SubsequentEventMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2014-02-28 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20131130_0_1276400x1271310"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesEPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-11-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20130131_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2013-01-31 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121130_0_1281195x1275455"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:ShortTermDebtTypeAxis"> us-gaap:ConvertibleNotesPayableMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-11-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <context id="eol_PE720058--14S-1-0007_STD_0_20121130_0_1276400x1281158"> | |||||||||||||||||||||
| <entity> | |||||||||||||||||||||
| <identifier scheme="http://www.sec.gov/CIK"> 0001374690 </identifier> | |||||||||||||||||||||
| <segment> | |||||||||||||||||||||
| <xbrldi:explicitMember dimension="us-gaap:StatementClassOfStockAxis"> us-gaap:SeriesDPreferredStockMember </xbrldi:explicitMember> | |||||||||||||||||||||
| </segment> | |||||||||||||||||||||
| </entity> | |||||||||||||||||||||
| <period> | |||||||||||||||||||||
| <instant> 2012-11-30 </instant> | |||||||||||||||||||||
| </period> | |||||||||||||||||||||
| </context> | |||||||||||||||||||||
| <unit id="shares"> | |||||||||||||||||||||
| <measure> shares </measure> | |||||||||||||||||||||
| </unit> | |||||||||||||||||||||
| <unit id="iso4217_USD_per_shares"> | |||||||||||||||||||||
| <divide> | |||||||||||||||||||||
| <unitNumerator> | |||||||||||||||||||||
| <measure> iso4217:USD </measure> | |||||||||||||||||||||
| </unitNumerator> | |||||||||||||||||||||
| <unitDenominator> | |||||||||||||||||||||
| <measure> shares </measure> | |||||||||||||||||||||
| </unitDenominator> | |||||||||||||||||||||
| </divide> | |||||||||||||||||||||
| </unit> | |||||||||||||||||||||
| <unit id="iso4217_USD"> | |||||||||||||||||||||
| <measure> iso4217:USD </measure> | |||||||||||||||||||||
| </unit> | |||||||||||||||||||||
| <unit id="pure"> | |||||||||||||||||||||
| <measure> pure </measure> | |||||||||||||||||||||
| </unit> | |||||||||||||||||||||
| <unit id="Vote"> | |||||||||||||||||||||
| <measure> zfgn:Vote </measure> | |||||||||||||||||||||
| </unit> | |||||||||||||||||||||
| <unit id="Installment"> | |||||||||||||||||||||
| <measure> zfgn:Installment </measure> | |||||||||||||||||||||
| </unit> | |||||||||||||||||||||
| </xbrl> | |||||||||||||||||||||