SEC Info - Ionis Pharmaceuticals Inc. - ‘8-K’ for 4/6/21

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Ionis Pharmaceuticals Inc. – ‘8-K’ for 4/6/21 – ‘XML’

On: Monday, 4/12/21, at 9:13pm ET · As of: 4/13/21 · For: 4/6/21 · Accession #: 1193125-21-113586 · File #: 0-19125

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 4/13/21  Ionis Pharmaceuticals Inc.        8-K:1,2,3,8 4/06/21   15:1.5M                                   Donnelley … Solutions/FA

Current Report — Form 8-K
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 8-K         Current Report                                      HTML     46K 
 2: EX-4.1      Instrument Defining the Rights of Security Holders  HTML    457K 
 3: EX-10.1     Material Contract                                   HTML    169K 
 4: EX-10.2     Material Contract                                   HTML    179K 
 5: EX-99.1     Miscellaneous Exhibit                               HTML     15K 
 6: EX-99.2     Miscellaneous Exhibit                               HTML     18K 
11: R1          Document and Entity Information                     HTML     47K 
13: XML         IDEA XML File -- Filing Summary                      XML     13K 
10: XML         XBRL Instance -- d158901d8k_htm                      XML     14K 
12: EXCEL       IDEA Workbook of Financial Reports                  XLSX      6K 
 8: EX-101.LAB  XBRL Labels -- ck0000874015-20210406_lab             XML     54K 
 9: EX-101.PRE  XBRL Presentations -- ck0000874015-20210406_pre      XML     34K 
 7: EX-101.SCH  XBRL Schema -- ck0000874015-20210406                 XSD     13K 
14: JSON        XBRL Instance as JSON Data -- MetaLinks               12±    19K 
15: ZIP         XBRL Zipped Folder -- 0001193125-21-113586-xbrl      Zip    184K

‘XML’ — XBRL Instance — d158901d8k_htm

This Document is an XBRL XML File.

<?xml version="1.0" encoding="windows-1252"?>

<link:schemaRef xlink:href="ck0000874015-20210406.xsd" xlink:type="simple"/>

</entity>

</period>

</context>

<dei:EntityRegistrantName contextRef="duration_2021-04-06_to_2021-04-06" id="Hidden_dei_EntityRegistrantName"> IONIS PHARMACEUTICALS INC </dei:EntityRegistrantName>

<dei:AmendmentFlag contextRef="duration_2021-04-06_to_2021-04-06"> false </dei:AmendmentFlag>

<dei:EntityCentralIndexKey contextRef="duration_2021-04-06_to_2021-04-06" id="Hidden_dei_EntityCentralIndexKey"> 0000874015 </dei:EntityCentralIndexKey>

<dei:DocumentType contextRef="duration_2021-04-06_to_2021-04-06"> 8-K </dei:DocumentType>

<dei:DocumentPeriodEndDate contextRef="duration_2021-04-06_to_2021-04-06"> 2021-04-06 </dei:DocumentPeriodEndDate>

<dei:EntityIncorporationStateCountryCode contextRef="duration_2021-04-06_to_2021-04-06"> DE </dei:EntityIncorporationStateCountryCode>

<dei:EntityFileNumber contextRef="duration_2021-04-06_to_2021-04-06"> 000-19125 </dei:EntityFileNumber>

<dei:EntityTaxIdentificationNumber contextRef="duration_2021-04-06_to_2021-04-06"> 33-0336973 </dei:EntityTaxIdentificationNumber>

<dei:EntityAddressAddressLine1 contextRef="duration_2021-04-06_to_2021-04-06"> 2855 Gazelle Court </dei:EntityAddressAddressLine1>

<dei:EntityAddressCityOrTown contextRef="duration_2021-04-06_to_2021-04-06"> Carlsbad </dei:EntityAddressCityOrTown>

<dei:EntityAddressStateOrProvince contextRef="duration_2021-04-06_to_2021-04-06"> CA </dei:EntityAddressStateOrProvince>

<dei:EntityAddressPostalZipCode contextRef="duration_2021-04-06_to_2021-04-06"> 92010 </dei:EntityAddressPostalZipCode>

<dei:CityAreaCode contextRef="duration_2021-04-06_to_2021-04-06"> (760) </dei:CityAreaCode>

<dei:LocalPhoneNumber contextRef="duration_2021-04-06_to_2021-04-06"> 931-9200 </dei:LocalPhoneNumber>

<dei:WrittenCommunications contextRef="duration_2021-04-06_to_2021-04-06"> false </dei:WrittenCommunications>

<dei:SolicitingMaterial contextRef="duration_2021-04-06_to_2021-04-06"> false </dei:SolicitingMaterial>

<dei:PreCommencementTenderOffer contextRef="duration_2021-04-06_to_2021-04-06"> false </dei:PreCommencementTenderOffer>

<dei:PreCommencementIssuerTenderOffer contextRef="duration_2021-04-06_to_2021-04-06"> false </dei:PreCommencementIssuerTenderOffer>

<dei:Security12bTitle contextRef="duration_2021-04-06_to_2021-04-06"> Common Stock, $.001 Par Value </dei:Security12bTitle>

<dei:TradingSymbol contextRef="duration_2021-04-06_to_2021-04-06"> IONS </dei:TradingSymbol>

<dei:SecurityExchangeName contextRef="duration_2021-04-06_to_2021-04-06"> NASDAQ </dei:SecurityExchangeName>

<dei:EntityEmergingGrowthCompany contextRef="duration_2021-04-06_to_2021-04-06"> false </dei:EntityEmergingGrowthCompany>

</xbrl>

4 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 2/21/24  Ionis Pharmaceuticals Inc.        10-K       12/31/23  103:18M
 2/22/23  Ionis Pharmaceuticals Inc.        10-K       12/31/22  110:25M
 2/25/22  Ionis Pharmaceuticals Inc.        10-K       12/31/21  106:22M
 8/05/21  Ionis Pharmaceuticals Inc.        S-8         8/05/21    3:71K                                    Broadridge Fin’l So… Inc

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