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| <?xml version="1.0" encoding="windows-1252"?> |
| <!-- XBRL Document Created with Wdesk from Workiva --> |
| <!-- Copyright 2023 Workiva --> |
| <!-- r:13c539ed-6c26-4c9d-91e4-fcf4c0fc5ead,g:d80b33a3-f5d7-4774-8ecb-17b433917e6a --> |
| <xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:wynn="http://www.wynnresorts.com/20230601" xmlns:xbrli="http://www.xbrl.org/2003/instance" attributeFormDefault="unqualified" elementFormDefault="qualified" targetNamespace="http://www.wynnresorts.com/20230601"> |
| <xs:import namespace="http://www.w3.org/1999/xlink" schemaLocation="http://www.xbrl.org/2003/xlink-2003-12-31.xsd"/> |
| <xs:import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/> |
| <xs:import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/> |
| <xs:import namespace="http://xbrl.sec.gov/dei/2022" schemaLocation="https://xbrl.sec.gov/dei/2022/dei-2022.xsd"/> |
| <xs:annotation> |
| | <xs:appinfo> |
| | | <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="wynn-20230601_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"/> |
| | | <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="wynn-20230601_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"/> |
| | | <link:roleType id="DocumentandEntityInformation" roleURI="http://www.wynnresorts.com/role/DocumentandEntityInformation"> |
| <link:definition> 0000001 - Document - Document and Entity Information </link:definition> |
| <link:usedOn> link:presentationLink </link:usedOn> |
| <link:usedOn> link:calculationLink </link:usedOn> |
| <link:usedOn> link:definitionLink </link:usedOn> |
| </link:roleType> |
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| <xs:element id="wynn_DEIAbstract" abstract="true" name="DEIAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/> |
| </xs:schema> |
