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Charles River Laboratories International, Inc. – ‘10-Q’ for 6/25/22 – ‘EX-101.SCH’

On:  Wednesday, 8/3/22, at 3:59pm ET   ·   For:  6/25/22   ·   Accession #:  1100682-22-28   ·   File #:  1-15943

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  As Of               Filer                 Filing    For·On·As Docs:Size

 8/03/22  Charles River Labs Int’l, Inc.    10-Q        6/25/22   79:9.7M

Quarterly Report   —   Form 10-Q

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-Q        Quarterly Report                                    HTML   2.15M 
 2: EX-31.1     Certification -- §302 - SOA'02                      HTML     27K 
 3: EX-31.2     Certification -- §302 - SOA'02                      HTML     27K 
 4: EX-32.1     Certification -- §906 - SOA'02                      HTML     25K 
10: R1          Cover Page                                          HTML     75K 
11: R2          Condensed Consolidated Statements of Income         HTML    110K 
                (Unaudited)                                                      
12: R3          Condensed Consolidated Statements of Comprehensive  HTML     60K 
                Income (Unaudited)                                               
13: R4          Condensed Consolidated Balance Sheets (Unaudited)   HTML    163K 
14: R5          Condensed Consolidated Balance Sheets (Unaudited)   HTML     45K 
                (Parenthetical)                                                  
15: R6          Condensed Consolidated Statements of Cash Flows     HTML    126K 
                (Unaudited)                                                      
16: R7          Condensed Consolidated Statements of Changes in     HTML     88K 
                Equity (Unaudited)                                               
17: R8          Basis of Presentation                               HTML     33K 
18: R9          Acquisitions and Divestitures                       HTML    122K 
19: R10         Revenue From Contracts With Customers               HTML     85K 
20: R11         Segment Information                                 HTML    134K 
21: R12         Supplemental Balance Sheet Information              HTML     71K 
22: R13         Venture Capital and Strategic Equity Investments    HTML     27K 
23: R14         Fair Value                                          HTML     86K 
24: R15         Goodwill and Intangible Assets                      HTML     63K 
25: R16         Debt and Other Financing Arrangements               HTML     55K 
26: R17         Equity and Noncontrolling Interests                 HTML     77K 
27: R18         Income Taxes                                        HTML     30K 
28: R19         Restructuring and Asset Impairments                 HTML     40K 
29: R20         Commitments and Contingencies                       HTML     26K 
30: R21         Basis of Presentation (Policies)                    HTML     45K 
31: R22         Acquisitions and Divestitures (Tables)              HTML    118K 
32: R23         Revenue From Contracts With Customers (Tables)      HTML    104K 
33: R24         Segment Information (Tables)                        HTML    163K 
34: R25         Supplemental Balance Sheet Information (Tables)     HTML     82K 
35: R26         Fair Value (Tables)                                 HTML     83K 
36: R27         Goodwill and Intangible Assets (Tables)             HTML     68K 
37: R28         Debt and Other Financing Arrangements (Tables)      HTML     52K 
38: R29         Equity and Noncontrolling Interests (Tables)        HTML     73K 
39: R30         Restructuring and Asset Impairments (Tables)        HTML     39K 
40: R31         Basis of Presentation (Details)                     HTML     24K 
41: R32         ACQUISITIONS AND DIVESTITURES - Narrative           HTML    141K 
                (Details)                                                        
42: R33         ACQUISITIONS AND DIVESTITURES - Purchase Price      HTML    102K 
                Allocation (Details)                                             
43: R34         ACQUISITIONS AND DIVESTITURES - Definite-Lived      HTML     62K 
                Intangible Assets (Details)                                      
44: R35         ACQUISITIONS AND DIVESTITURES - Pro Forma           HTML     29K 
                Information (Details)                                            
45: R36         ACQUISITIONS AND DIVESTITURES - Schedule of         HTML     67K 
                Divestitures (Details)                                           
46: R37         ACQUISITIONS AND DIVESTITURES - Transaction and     HTML     25K 
                Integration Costs (Details)                                      
47: R38         REVENUE FROM CONTRACTS WITH CUSTOMERS -             HTML     45K 
                Disaggregation of Revenues by Major Business Line                
                (Details)                                                        
48: R39         REVENUE FROM CONTRACTS WITH CUSTOMERS - Schedule    HTML     51K 
                of Estimated Revenue Related to Performance                      
                Obligations (Details)                                            
49: R40         REVENUE FROM CONTRACTS WITH CUSTOMERS - Narrative   HTML     39K 
                (Details)                                                        
50: R41         REVENUE FROM CONTRACTS WITH CUSTOMERS - Schedule    HTML     30K 
                of Client Receivables, Contract Assets and                       
                Contract Liabilities (Details)                                   
51: R42         SEGMENT INFORMATION - Narrative (Details)           HTML     24K 
52: R43         SEGMENT INFORMATION - Revenue and Other Financial   HTML     48K 
                Information by Reportable Segment (Details)                      
53: R44         SEGMENT INFORMATION - Reconciliation of Segment     HTML     38K 
                Operating Income, Depreciation and Amortization,                 
                and Capital Expenditures (Details)                               
54: R45         SEGMENT INFORMATION - Revenue Per Significant       HTML     35K 
                Product or Service (Details)                                     
55: R46         SEGMENT INFORMATION - Summary of Unallocated        HTML     40K 
                Corporate Overhead (Details)                                     
56: R47         SEGMENT INFORMATION - Disaggregation of Revenue by  HTML     39K 
                Geographic Area (Details)                                        
57: R48         Supplemental Balance Sheet Information (Details)    HTML    106K 
58: R49         VENTURE CAPITAL AND STRATEGIC EQUITY INVESTMENTS -  HTML     60K 
                Narrative (Details)                                              
59: R50         FAIR VALUE - Fair Value of Assets and Liabilities   HTML     57K 
                (Details)                                                        
60: R51         FAIR VALUE - Contingent Consideration (Details)     HTML     37K 
61: R52         FAIR VALUE - Narrative (Details)                    HTML     39K 
62: R53         FAIR VALUE - Schedule of Fair Value of Debt         HTML     42K 
                (Details)                                                        
63: R54         GOODWILL AND INTANGIBLE ASSETS - Rollforward of     HTML     38K 
                Goodwill (Details)                                               
64: R55         GOODWILL AND INTANGIBLE ASSETS - Schedule of        HTML     47K 
                Intangible Assets (Details)                                      
65: R56         DEBT AND OTHER FINANCING ARRANGEMENTS - Schedule    HTML     57K 
                of Long-Term Debt (Details)                                      
66: R57         DEBT AND OTHER FINANCING ARRANGEMENTS - Narrative   HTML     44K 
                (Details)                                                        
67: R58         DEBT AND OTHER FINANCING ARRANGEMENTS - Cross       HTML     34K 
                Currency Loans (Details)                                         
68: R59         EQUITY AND NONCONTROLLING INTERESTS - Earnings Per  HTML     64K 
                Share (Details)                                                  
69: R60         EQUITY AND NONCONTROLLING INTERESTS - Narrative     HTML     60K 
                (Details)                                                        
70: R61         EQUITY AND NONCONTROLLING INTERESTS - Accumulated   HTML     63K 
                Other Comprehensive Income (Loss) (Details)                      
71: R62         EQUITY AND NONCONTROLLING INTERESTS - Rollforward   HTML     34K 
                of Redeemable Noncontrolling Interest (Details)                  
72: R63         Income Taxes (Details)                              HTML     38K 
73: R64         RESTRUCTURING AND ASSET IMPAIRMENTS -               HTML     35K 
                Restructuring Costs by Reportable Segment                        
                (Details)                                                        
74: R65         RESTRUCTURING AND ASSET IMPAIRMENTS - Narrative     HTML     25K 
                (Details)                                                        
77: XML         IDEA XML File -- Filing Summary                      XML    144K 
75: XML         XBRL Instance -- crl-20220625_htm                    XML   2.67M 
76: EXCEL       IDEA Workbook of Financial Reports                  XLSX    158K 
 6: EX-101.CAL  XBRL Calculations -- crl-20220625_cal                XML    247K 
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 8: EX-101.LAB  XBRL Labels -- crl-20220625_lab                      XML   1.64M 
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78: JSON        XBRL Instance as JSON Data -- MetaLinks              418±   633K 
79: ZIP         XBRL Zipped Folder -- 0001100682-22-000028-xbrl      Zip    453K

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<link:definition> 2423415 - Disclosure - SEGMENT INFORMATION - Revenue Per Significant Product or Service (Details) </link:definition>
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<link:definition> 2424416 - Disclosure - SEGMENT INFORMATION - Summary of Unallocated Corporate Overhead (Details) </link:definition>
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<link:definition> 2425417 - Disclosure - SEGMENT INFORMATION - Disaggregation of Revenue by Geographic Area (Details) </link:definition>
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<link:definition> 2126105 - Disclosure - SUPPLEMENTAL BALANCE SHEET INFORMATION </link:definition>
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<link:usedOn> link:calculationLink </link:usedOn>
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<link:definition> 2327304 - Disclosure - SUPPLEMENTAL BALANCE SHEET INFORMATION (Tables) </link:definition>
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<link:usedOn> link:calculationLink </link:usedOn>
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<link:definition> 2428418 - Disclosure - SUPPLEMENTAL BALANCE SHEET INFORMATION (Details) </link:definition>
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<link:usedOn> link:calculationLink </link:usedOn>
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<link:definition> 2129106 - Disclosure - VENTURE CAPITAL AND STRATEGIC EQUITY INVESTMENTS </link:definition>
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<link:definition> 2430419 - Disclosure - VENTURE CAPITAL AND STRATEGIC EQUITY INVESTMENTS - Narrative (Details) </link:definition>
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<link:definition> 2131107 - Disclosure - FAIR VALUE </link:definition>
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<link:definition> 2332305 - Disclosure - FAIR VALUE (Tables) </link:definition>
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<link:definition> 2433420 - Disclosure - FAIR VALUE - Fair Value of Assets and Liabilities (Details) </link:definition>
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<link:definition> 2434421 - Disclosure - FAIR VALUE - Contingent Consideration (Details) </link:definition>
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<link:usedOn> link:calculationLink </link:usedOn>
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<link:definition> 2435422 - Disclosure - FAIR VALUE - Narrative (Details) </link:definition>
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<link:definition> 2436423 - Disclosure - FAIR VALUE - Schedule of Fair Value of Debt (Details) </link:definition>
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<link:definition> 2137108 - Disclosure - GOODWILL AND INTANGIBLE ASSETS </link:definition>
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<link:usedOn> link:calculationLink </link:usedOn>
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<link:definition> 2338306 - Disclosure - GOODWILL AND INTANGIBLE ASSETS (Tables) </link:definition>
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<link:definition> 2439424 - Disclosure - GOODWILL AND INTANGIBLE ASSETS - Rollforward of Goodwill (Details) </link:definition>
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<link:definition> 2440425 - Disclosure - GOODWILL AND INTANGIBLE ASSETS - Schedule of Intangible Assets (Details) </link:definition>
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<link:definition> 2141109 - Disclosure - DEBT AND OTHER FINANCING ARRANGEMENTS </link:definition>
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<link:definition> 2342307 - Disclosure - DEBT AND OTHER FINANCING ARRANGEMENTS (Tables) </link:definition>
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<link:definition> 2443426 - Disclosure - DEBT AND OTHER FINANCING ARRANGEMENTS - Schedule of Long-Term Debt (Details) </link:definition>
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<link:definition> 2444427 - Disclosure - DEBT AND OTHER FINANCING ARRANGEMENTS - Narrative (Details) </link:definition>
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<link:definition> 2445428 - Disclosure - DEBT AND OTHER FINANCING ARRANGEMENTS - Cross Currency Loans (Details) </link:definition>
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<link:definition> 2146110 - Disclosure - EQUITY AND NONCONTROLLING INTERESTS </link:definition>
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<link:definition> 2347308 - Disclosure - EQUITY AND NONCONTROLLING INTERESTS (Tables) </link:definition>
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<link:definition> 2448429 - Disclosure - EQUITY AND NONCONTROLLING INTERESTS - Earnings Per Share (Details) </link:definition>
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<link:definition> 2449430 - Disclosure - EQUITY AND NONCONTROLLING INTERESTS - Narrative (Details) </link:definition>
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<link:definition> 2450431 - Disclosure - EQUITY AND NONCONTROLLING INTERESTS - Accumulated Other Comprehensive Income (Loss) (Details) </link:definition>
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<link:definition> 2451432 - Disclosure - EQUITY AND NONCONTROLLING INTERESTS - Rollforward of Redeemable Noncontrolling Interest (Details) </link:definition>
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<link:definition> 2152111 - Disclosure - INCOME TAXES </link:definition>
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<link:definition> 2453433 - Disclosure - INCOME TAXES (Details) </link:definition>
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<link:definition> 2154112 - Disclosure - RESTRUCTURING AND ASSET IMPAIRMENTS </link:definition>
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<link:definition> 2355309 - Disclosure - RESTRUCTURING AND ASSET IMPAIRMENTS (Tables) </link:definition>
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<link:definition> 2456434 - Disclosure - RESTRUCTURING AND ASSET IMPAIRMENTS - Restructuring Costs by Reportable Segment (Details) </link:definition>
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<xs:element id="crl_NetIncomeLossIncludingPortionAttributableToNoncontrollingInterestAndExcludingRedeemableNoncontrollingInterest" abstract="false" name="NetIncomeLossIncludingPortionAttributableToNoncontrollingInterestAndExcludingRedeemableNoncontrollingInterest" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_CognateBioServicesIncAndViegeneBiosciencesIncMember" abstract="true" name="CognateBioServicesIncAndViegeneBiosciencesIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_SeniorNotesDue2031Member" abstract="true" name="SeniorNotesDue2031Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_AccruedInterestAndOtherLiabilitiesCurrent" abstract="false" name="AccruedInterestAndOtherLiabilitiesCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLeaseAssets" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLeaseAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_ResearchModelsAndServicesMember" abstract="true" name="ResearchModelsAndServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_DSASupplierMember" abstract="true" name="DSASupplierMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_ExploraBioLabsHoldingsIncMember" abstract="true" name="ExploraBioLabsHoldingsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_VigeneBiosciencesIncMember" abstract="true" name="VigeneBiosciencesIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_SupplierMember" abstract="true" name="SupplierMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_BusinessCombinationIntegrationRelatedCostsAndTransactionCosts" abstract="false" name="BusinessCombinationIntegrationRelatedCostsAndTransactionCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_ComprehensiveIncomeLossNetOfTax" abstract="false" name="ComprehensiveIncomeLossNetOfTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_EquityMethodInvestmentContingentLiability" abstract="false" name="EquityMethodInvestmentContingentLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_ContractWithCustomerTermsOfPayment" abstract="false" name="ContractWithCustomerTermsOfPayment" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
<xs:element id="crl_ScheduleOfOtherLiabilitiesNoncurrentTableTextBlock" abstract="false" name="ScheduleOfOtherLiabilitiesNoncurrentTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
<xs:element id="crl_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityChangeInPreviouslyRecordedAdjustment" abstract="false" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityChangeInPreviouslyRecordedAdjustment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_OtherAcquisitionsMember" abstract="true" name="OtherAcquisitionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_ContractWithCustomerPercentageOfLiabilitiesRecognizedAsRevenue" abstract="false" name="ContractWithCustomerPercentageOfLiabilitiesRecognizedAsRevenue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="crl_IncreaseDecreaseInContractWithCustomerLiabilityCustomerDeposits" abstract="false" name="IncreaseDecreaseInContractWithCustomerLiabilityCustomerDeposits" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_CDMOSiteMember" abstract="true" name="CDMOSiteMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_BusinessCombinationOwnershipPercentageNotAcquired" abstract="false" name="BusinessCombinationOwnershipPercentageNotAcquired" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="crl_ContractWithCustomerUnpaidAdvancedClientBillings" abstract="false" name="ContractWithCustomerUnpaidAdvancedClientBillings" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_ManufacturingSupportMember" abstract="true" name="ManufacturingSupportMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_VitalRiverMember" abstract="true" name="VitalRiverMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_TotalEquityAttributabletoCommonShareholdersMember" abstract="true" name="TotalEquityAttributabletoCommonShareholdersMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_UnallocatedCorporateOverhead" abstract="false" name="UnallocatedCorporateOverhead" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_EquityMethodInvestmentInvestmentCommitment" abstract="false" name="EquityMethodInvestmentInvestmentCommitment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_SalariesAndBonus" abstract="false" name="SalariesAndBonus" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_EquityMethodInvestmentInvestmentCommitmentAmountFunded" abstract="false" name="EquityMethodInvestmentInvestmentCommitmentAmountFunded" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_OtherMember" abstract="true" name="OtherMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_ScheduleOfOtherLiabilitiesCurrentTableTextBlock" abstract="false" name="ScheduleOfOtherLiabilitiesCurrentTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
<xs:element id="crl_TemporaryEquityIncreaseDecreaseToNoncontrollingInterest" abstract="false" name="TemporaryEquityIncreaseDecreaseToNoncontrollingInterest" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_DisposalGroupIncludingDiscontinuedOperationOperatingLeaseRightOfUseAssetsNet" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationOperatingLeaseRightOfUseAssetsNet" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_SeniorNotesDue2029Member" abstract="true" name="SeniorNotesDue2029Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_LongTermDebtAndLeaseObligationNetOfCurrentPortion" abstract="false" name="LongTermDebtAndLeaseObligationNetOfCurrentPortion" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_ContractWithCustomerAssetPercentageOfAmountReclassifiedToReceivable" abstract="false" name="ContractWithCustomerAssetPercentageOfAmountReclassifiedToReceivable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="crl_GoodwillAcquiredNotDeductibleForIncomeTaxes" abstract="false" name="GoodwillAcquiredNotDeductibleForIncomeTaxes" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_IncomeLossFromVentureCapitalInvestments" abstract="false" name="IncomeLossFromVentureCapitalInvestments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_RetrogenixLimitedMember" abstract="true" name="RetrogenixLimitedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_OtherAssetsFairValueDisclosureAbstract" abstract="true" name="OtherAssetsFairValueDisclosureAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
<xs:element id="crl_BusinessCombinationConsiderationLiabilityContingentUponFuturePerformance" abstract="false" name="BusinessCombinationConsiderationLiabilityContingentUponFuturePerformance" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_DisposalGroupIncludingDiscontinuedOperationOperatingLeaseLiability" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationOperatingLeaseLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_DiscoveryandSafetyAssessmentMember" abstract="true" name="DiscoveryandSafetyAssessmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_ScheduleOfUnallocatedCorporateOverheadTableTextBlock" abstract="false" name="ScheduleOfUnallocatedCorporateOverheadTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
<xs:element id="crl_CognateBioServicesIncMember" abstract="true" name="CognateBioServicesIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_OtherLiabilitiesCurrentFairValueDisclosureAbstract" abstract="true" name="OtherLiabilitiesCurrentFairValueDisclosureAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
<xs:element id="crl_DepreciationAndAmortizationExpenseMember" abstract="true" name="DepreciationAndAmortizationExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_NoncontrollingInterestIncreaseDecreaseInRedemptionValue" abstract="false" name="NoncontrollingInterestIncreaseDecreaseInRedemptionValue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_OtherLiabilitiesNonCurrentFairValueDisclosureAbstract" abstract="true" name="OtherLiabilitiesNonCurrentFairValueDisclosureAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
<xs:element id="crl_DistributedBioIncMember" abstract="true" name="DistributedBioIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_OtherLongTermDebtMember" abstract="true" name="OtherLongTermDebtMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_EquityMethodInvestmentIncreaseDecreaseInOwnershipPercentageByParent" abstract="false" name="EquityMethodInvestmentIncreaseDecreaseInOwnershipPercentageByParent" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="crl_GoodwillAcquiredDuringPeriodNet" abstract="false" name="GoodwillAcquiredDuringPeriodNet" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="crl_SupplementalBalanceSheetInformationAbstract" abstract="true" name="SupplementalBalanceSheetInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
<xs:element id="crl_SeniorNotesDue2026Member" abstract="true" name="SeniorNotesDue2026Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_FiniteLivedIntangibleAssetsOtherThanCustomerRelationshipsMember" abstract="true" name="FiniteLivedIntangibleAssetsOtherThanCustomerRelationshipsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="crl_TransactionCosts" abstract="false" name="TransactionCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>

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