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Illumina, Inc. – ‘10-K’ for 1/2/22 – ‘EX-101.SCH’

On:  Friday, 2/18/22, at 3:11pm ET   ·   For:  1/2/22   ·   Accession #:  1110803-22-13   ·   File #:  1-35406

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  As Of               Filer                 Filing    For·On·As Docs:Size

 2/18/22  Illumina, Inc.                    10-K        1/02/22  108:15M

Annual Report   —   Form 10-K

Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 10-K        Annual Report                                       HTML   1.59M 
 2: EX-21.1     Subsidiaries List                                   HTML     42K 
 3: EX-23.1     Consent of Expert or Counsel                        HTML     31K 
 4: EX-31.1     Certification -- §302 - SOA'02                      HTML     38K 
 5: EX-31.2     Certification -- §302 - SOA'02                      HTML     37K 
 6: EX-32.1     Certification -- §906 - SOA'02                      HTML     33K 
 7: EX-32.2     Certification -- §906 - SOA'02                      HTML     33K 
13: R1          Cover Page                                          HTML     95K 
14: R2          Audit Information                                   HTML     36K 
15: R3          Consolidated Balance Sheets                         HTML    138K 
16: R4          Consolidated Balance Sheets (Parenthetical)         HTML     51K 
17: R5          Consolidated Statements of Income                   HTML    143K 
18: R6          Consolidated Statements of Comprehensive Income     HTML     60K 
19: R7          Consolidated Statements of Stockholders' Equity     HTML     90K 
20: R8          Consolidated Statements of Cash Flows               HTML    156K 
21: R9          Organization and Significant Accounting Policies    HTML    106K 
22: R10         Revenue                                             HTML     81K 
23: R11         Investments and Fair Value Measurements             HTML    142K 
24: R12         Acquisitions, Goodwill and Intangible Assets        HTML    126K 
25: R13         Debt and Other Commitments                          HTML     95K 
26: R14         Stockholders' Equity                                HTML    137K 
27: R15         Supplemental Balance Sheet and Statement of Income  HTML     92K 
                Details                                                          
28: R16         Legal Proceedings                                   HTML     43K 
29: R17         Income Taxes                                        HTML    126K 
30: R18         Employee Benefit Plans                              HTML     36K 
31: R19         Segments and Geographic Data                        HTML     99K 
32: R20         Organization and Significant Accounting Policies    HTML    152K 
                (Policies)                                                       
33: R21         Organization and Significant Accounting Policies    HTML     59K 
                (Tables)                                                         
34: R22         Revenue (Tables)                                    HTML     75K 
35: R23         Investments and Fair Value Measurements (Tables)    HTML    128K 
36: R24         Acquisitions, Goodwill and Intangible Assets        HTML    123K 
                (Tables)                                                         
37: R25         Debt and Other Commitments (Tables)                 HTML     82K 
38: R26         Stockholders' Equity (Tables)                       HTML    188K 
39: R27         Supplemental Balance Sheet and Statement of Income  HTML    113K 
                Details (Tables)                                                 
40: R28         Income Taxes (Tables)                               HTML    127K 
41: R29         Segments and Geographic Data (Tables)               HTML     92K 
42: R30         Organization and Significant Accounting Policies -  HTML     50K 
                Narrative - Concentrations of Risk (Details)                     
43: R31         Organization and Significant Accounting Policies -  HTML     34K 
                Narrative - Revenue Recognition (Details)                        
44: R32         Organization and Significant Accounting Policies -  HTML     44K 
                Summary of Calculation of Weighted Average Shares                
                used to Calculate Basic and Diluted Earnings Per                 
                Share (Details)                                                  
45: R33         Organization and Significant Accounting Policies -  HTML     46K 
                Summary of Estimated Useful Lives of Major Classes               
                of Property and Equipment (Details)                              
46: R34         Organization and Significant Accounting Policies -  HTML     41K 
                Narrative - Leases (Details)                                     
47: R35         Organization and Significant Accounting Policies -  HTML     40K 
                Narrative - Derivatives (Details)                                
48: R36         Organization and Significant Accounting Policies -  HTML     39K 
                Narrative - Warranties (Details)                                 
49: R37         Organization and Significant Accounting Policies -  HTML     33K 
                Narrative - Share-Based Compensation (Details)                   
50: R38         Organization and Significant Accounting Policies -  HTML     33K 
                Narrative - Advertising Costs (Details)                          
51: R39         Organization and Significant Accounting Policies -  HTML     52K 
                Narrative - Recently Adopted Accounting Policies                 
                (Details)                                                        
52: R40         Revenue - Summary of Disaggregated Revenue          HTML     70K 
                (Details)                                                        
53: R41         Revenue - Remaining Performance Obligation          HTML     49K 
                (Details)                                                        
54: R42         Revenue - Narrative (Details)                       HTML     43K 
55: R43         Investments and Fair Value Measurements - Summary   HTML     47K 
                of Short-term Investments (Details)                              
56: R44         Investments and Fair Value Measurements -           HTML    182K 
                Narrative (Details)                                              
57: R45         Investments and Fair Value Measurements -           HTML     37K 
                Marketable Equity Securities (Details)                           
58: R46         Investments and Fair Value Measurements - Summary   HTML     97K 
                of Hierarchy??for Assets and Liabilities Measured                
                at Fair Value Recurring Basis (Details)                          
59: R47         Investments and Fair Value Measurements - Changes   HTML     53K 
                in Estimated Fair Value of Acquisition Related                   
                Contingent Consideration Liabilities (Details)                   
60: R48         Acquisitions, Goodwill and Intangible Assets -      HTML    153K 
                Narrative (Details)                                              
61: R49         Acquisitions, Goodwill and Intangible Assets -      HTML     46K 
                Summary of Total Purchase Price (Details)                        
62: R50         Acquisitions, Goodwill and Intangible Assets -      HTML     72K 
                Preliminary Fair Value of Assets Acquired and                    
                Liabilities Assumed (Details)                                    
63: R51         Acquisitions, Goodwill and Intangible Assets -      HTML     50K 
                Summary of Amount Assigned to Identifiable                       
                Intangible Assets (Details)                                      
64: R52         Acquisitions, Goodwill and Intangible Assets -      HTML     37K 
                Summary of Pro Forma Information (Details)                       
65: R53         Acquisitions, Goodwill and Intangible Assets -      HTML     39K 
                Summary of Changes in Goodwill (Details)                         
66: R54         Acquisitions, Goodwill and Intangible Assets -      HTML     68K 
                Summary of Identifiable Intangible Assets                        
                (Details)                                                        
67: R55         Acquisitions, Goodwill and Intangible Assets -      HTML     47K 
                Summary of Estimated Annual Amortization of                      
                Intangible Assets (Details)                                      
68: R56         Debt and Other Commitments - Summary of Debt        HTML     79K 
                Obligations (Details)                                            
69: R57         Debt and Other Commitments - Narrative (Details)    HTML    137K 
70: R58         Debt and Other Commitments - Summary of Debt        HTML     42K 
                Conversions (Details)                                            
71: R59         Debt and Other Commitments - Summary of Maturities  HTML     61K 
                of Operating Lease Liabilities (Details)                         
72: R60         Debt and Other Commitments - Summary of Lease       HTML     38K 
                Costs (Details)                                                  
73: R61         Stockholders' Equity - Narrative (Details)          HTML     35K 
74: R62         Stockholders' Equity - Narrative - Restricted       HTML     38K 
                Stock (Details)                                                  
75: R63         Stockholders' Equity - Summary of Restricted Stock  HTML     66K 
                Activity and Related Information (Details)                       
76: R64         Stockholders' Equity - Summary of Pre-tax           HTML     40K 
                Intrinsic Values and Total Fair Value of Vested                  
                Restricted Stock (Details)                                       
77: R65         Stockholders' Equity - Summary of Stock Option      HTML     61K 
                Activity Under all Stock Option Plans (Details)                  
78: R66         Stockholders' Equity - Narrative - Stock Options    HTML     47K 
                (Details)                                                        
79: R67         Stockholders' Equity - Narrative -                  HTML     55K 
                Liability-Classified Award (Details)                             
80: R68         Stockholders' Equity - Narrative - Employee Stock   HTML     43K 
                Purchase Plan (Details)                                          
81: R69         Stockholders' Equity - Narrative - Share            HTML     42K 
                Repurchases (Details)                                            
82: R70         Stockholders' Equity - Summary of Share-based       HTML     48K 
                Compensation Expense for all Stock Awards                        
                (Details)                                                        
83: R71         Stockholders' Equity - Narrative- Share-based       HTML     65K 
                Compensation (Details)                                           
84: R72         Stockholders' Equity - Summary of Assumptions used  HTML     60K 
                to Estimate the Weighted-Average Fair Value Per                  
                Share for Stock Purchase under the Employee Stock                
                Purchase Plan (Details)                                          
85: R73         Supplemental Balance Sheet and Statement of Income  HTML     39K 
                Details - Summary of Accounts Receivable (Details)               
86: R74         Supplemental Balance Sheet and Statement of Income  HTML     41K 
                Details - Summary of Inventory (Details)                         
87: R75         Supplemental Balance Sheet and Statement of Income  HTML     53K 
                Details - Summary of Property and Equipment                      
                (Details)                                                        
88: R76         Supplemental Balance Sheet and Statement of Income  HTML     34K 
                Details - Narrative - Property and Equipment                     
                (Details)                                                        
89: R77         Supplemental Balance Sheet and Statement of Income  HTML     50K 
                Details - Summary of Accrued Liabilities (Details)               
90: R78         Supplemental Balance Sheet and Statement of Income  HTML     39K 
                Details - Summary of Changes in Reserve for                      
                Product Warranties (Details)                                     
91: R79         Supplemental Balance Sheet and Statement of Income  HTML     47K 
                Details - Other Income, Net (Details)                            
92: R80         Legal Proceedings (Details)                         HTML     37K 
93: R81         Income Taxes - Summary of Income (Loss) Before      HTML     41K 
                Income Taxes by Region (Details)                                 
94: R82         Income Taxes - Summary of Provision for Income      HTML     59K 
                Taxes (Details)                                                  
95: R83         Income Taxes - Summary of Reconciliation of         HTML     62K 
                Provision for Income Taxes to Amount Computed by                 
                Applying the Federal Statutory Rate (Details)                    
96: R84         Income Taxes - Narrative (Details)                  HTML     68K 
97: R85         Income Taxes - Summary of Significant Components    HTML     74K 
                of Deferred Tax Assets and Liabilities (Details)                 
98: R86         Income Taxes - Summary of the Gross Amount of       HTML     43K 
                Uncertain Tax Positions (Details)                                
99: R87         Employee Benefit Plans (Details)                    HTML     51K 
100: R88         Segments and Geographic Data - Narrative (Details)  HTML     33K  
101: R89         Segments and Geographic Data - Summary of           HTML     70K  
                Operating Performance and Assets by Segment                      
                (Details)                                                        
102: R90         Segments and Geographic Data - Summary of Net       HTML     42K  
                Long-lived Assets Consisting of Property and                     
                Equipment (Details)                                              
103: R9999       Uncategorized Items - ilmn-20220102.htm             HTML     49K  
106: XML         IDEA XML File -- Filing Summary                      XML    203K  
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105: EXCEL       IDEA Workbook of Financial Reports                  XLSX    154K  
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12: EX-101.PRE  XBRL Presentations -- ilmn-20220102_pre              XML   1.60M 
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107: JSON        XBRL Instance as JSON Data -- MetaLinks              614±   933K  
108: ZIP         XBRL Zipped Folder -- 0001110803-22-000013-xbrl      Zip    912K

‘EX-101.SCH’   —   XBRL Schema — ilmn-20220102

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<xs:element id="ilmn_BusinessAcquisitionEquityOrDebtFinancingThreshold" abstract="false" name="BusinessAcquisitionEquityOrDebtFinancingThreshold" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_TermNotesDue2023Member" abstract="true" name="TermNotesDue2023Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_LiabilityBasedAwardsMember" abstract="true" name="LiabilityBasedAwardsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_ShareBasedCompensationArrangementByShareBasedPaymentAwardLiabilityClassifiedAwardAggregateIntrinsicValueNonvested" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardLiabilityClassifiedAwardAggregateIntrinsicValueNonvested" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_RemainingCapitalCommitment" abstract="false" name="RemainingCapitalCommitment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_GainLossOnStrategicInvestmentsNoncash" abstract="false" name="GainLossOnStrategicInvestmentsNoncash" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_ShareBasedPaymentArrangementPerformanceStockOptionMember" abstract="true" name="ShareBasedPaymentArrangementPerformanceStockOptionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_ConvertibleSeniorNotesDue2023Member" abstract="true" name="ConvertibleSeniorNotesDue2023Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_StockIssuedDuringPeriodNetOfRepurchasesValue" abstract="false" name="StockIssuedDuringPeriodNetOfRepurchasesValue" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_CoreIlluminaMember" abstract="true" name="CoreIlluminaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFive" abstract="false" name="FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFive" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_BusinessAcquisitionContingentValueRightsProRataTwoPercentage" abstract="false" name="BusinessAcquisitionContingentValueRightsProRataTwoPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="ilmn_IncreaseDecreaseOfOperatingLeasesNet" abstract="false" name="IncreaseDecreaseOfOperatingLeasesNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_DebtInstrumentConvertibleThresholdPercentageOfNotePriceTrigger" abstract="false" name="DebtInstrumentConvertibleThresholdPercentageOfNotePriceTrigger" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="ilmn_VentureCapitalInvestmentFundTheFundTwoMember" abstract="true" name="VentureCapitalInvestmentFundTheFundTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_PropertyPlantAndEquipmentNetAndOperatingLeaseRightOfUseAssets" abstract="false" name="PropertyPlantAndEquipmentNetAndOperatingLeaseRightOfUseAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_ConcentrationRiskThreshold" abstract="false" name="ConcentrationRiskThreshold" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="ilmn_BusinessCombinationConsiderationTransferredInvestmentHeldPreviously" abstract="false" name="BusinessCombinationConsiderationTransferredInvestmentHeldPreviously" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_RevenueRecognitionMultipleDeliverableArrangementsDeliveryTimeFrame" abstract="false" name="RevenueRecognitionMultipleDeliverableArrangementsDeliveryTimeFrame" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
<xs:element id="ilmn_IncomeTaxExpenseBenefitFinalizationOfCourtCase" abstract="false" name="IncomeTaxExpenseBenefitFinalizationOfCourtCase" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_ConvertibleSeniorNotesDue2021Member" abstract="true" name="ConvertibleSeniorNotesDue2021Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_OtherAcquisitionMember" abstract="true" name="OtherAcquisitionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherCurrentAndNoncurrentLiabilities" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherCurrentAndNoncurrentLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_DeferredCompensationPlanMaximumAnnualContributionsPerEmployeeOtherCompensationPercent" abstract="false" name="DeferredCompensationPlanMaximumAnnualContributionsPerEmployeeOtherCompensationPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
<xs:element id="ilmn_EffectiveIncomeTaxRateReconciliationCostSharingAdjustments" abstract="false" name="EffectiveIncomeTaxRateReconciliationCostSharingAdjustments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseRightOfUseAssets" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseRightOfUseAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_BridgeFacilityMember" abstract="true" name="BridgeFacilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_TermNotesMember" abstract="true" name="TermNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_ContingentValueUnrealizedGainLoss" abstract="false" name="ContingentValueUnrealizedGainLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_BusinessAcquisitionContingentValueRightsTerm" abstract="false" name="BusinessAcquisitionContingentValueRightsTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
<xs:element id="ilmn_PaymentRightsOfAboveOneBillionEachTwelveYearsMember" abstract="true" name="PaymentRightsOfAboveOneBillionEachTwelveYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_SequencingMember" abstract="true" name="SequencingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_SwinglineBorrowingsMember" abstract="true" name="SwinglineBorrowingsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_MicroarrayMember" abstract="true" name="MicroarrayMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_A2015StockAndIncentiveCompensationPlanMember" abstract="true" name="A2015StockAndIncentiveCompensationPlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_InstrumentsMember" abstract="true" name="InstrumentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_ProceedsFromStrategicInvestments" abstract="false" name="ProceedsFromStrategicInvestments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_SeniorLevelEmployeeMember" abstract="true" name="SeniorLevelEmployeeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_BusinessCombinationContingentConsiderationLiabilityMember" abstract="true" name="BusinessCombinationContingentConsiderationLiabilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_ContinuationAdvancesMember" abstract="true" name="ContinuationAdvancesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_OtherNonoperatingIncomeExpenseMiscellaneous" abstract="false" name="OtherNonoperatingIncomeExpenseMiscellaneous" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_BusinessCombinationContingentValueRightsExchanged" abstract="false" name="BusinessCombinationContingentValueRightsExchanged" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
<xs:element id="ilmn_BusinessCombinationAndGoodwillAndIntangibleAssetsAbstract" abstract="true" name="BusinessCombinationAndGoodwillAndIntangibleAssetsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
<xs:element id="ilmn_PacificBiosciencesofCaliforniaIncPacBioMember" abstract="true" name="PacificBiosciencesofCaliforniaIncPacBioMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_ContingentValueRightFairValueDisclosure" abstract="false" name="ContingentValueRightFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_ContingentPaymentRightsDomain" abstract="true" name="ContingentPaymentRightsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_ReplacementAwardsMember" abstract="true" name="ReplacementAwardsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_SBNorthstarLPMember" abstract="true" name="SBNorthstarLPMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
<xs:element id="ilmn_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseLiabilityNoncurrent" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseLiabilityNoncurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
<xs:element id="ilmn_DebtInstrumentConvertibleObservationPeriod" abstract="false" name="DebtInstrumentConvertibleObservationPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
<xs:element id="ilmn_GRAILInc.Member" abstract="true" name="GRAILInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>

13 Subsequent Filings that Reference this Filing

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

 8/10/23  Illumina, Inc.                    10-Q        7/02/23   73:8.1M
 5/05/23  Illumina, Inc.                    10-Q        4/02/23   67:7.1M
 2/17/23  Illumina, Inc.                    10-K        1/01/23  108:17M
 2/07/23  Illumina, Inc.                    8-K:2,9     2/07/23   11:1.2M
 1/11/23  Illumina, Inc.                    8-K:2,9     1/09/23   13:332K
12/01/22  Illumina, Inc.                    424B2                  2:533K                                   Donnelley … Solutions/FA
11/29/22  Illumina, Inc.                    424B2                  1:500K                                   Donnelley … Solutions/FA
11/04/22  Illumina, Inc.                    10-Q       10/02/22   70:8.9M
11/03/22  Illumina, Inc.                    8-K:2,9    11/03/22   11:1.1M
 8/11/22  Illumina, Inc.                    10-Q        7/03/22   72:9M
 8/11/22  Illumina, Inc.                    8-K:2,9     8/11/22   11:1M
 5/05/22  Illumina, Inc.                    10-Q        4/03/22   68:7.4M
 5/05/22  Illumina, Inc.                    8-K:2,9     5/05/22   11:621K

33 Previous Filings that this Filing References

  As Of               Filer                 Filing    For·On·As Docs:Size             Issuer                      Filing Agent

11/05/21  Illumina, Inc.                    10-Q       10/03/21   77:9.8M
 8/18/21  Illumina, Inc.                    8-K:1,2,8,9 8/18/21   12:686K                                   Cravath Swaine & … 01/FA
 3/22/21  Illumina, Inc.                    8-K:8,9     3/16/21   13:540K                                   Donnelley … Solutions/FA
 3/12/21  Illumina, Inc.                    S-3ASR      3/12/21    5:694K                                   Donnelley … Solutions/FA
 3/08/21  Illumina, Inc.                    8-K:1,9     3/08/21   11:1.1M                                   Donnelley … Solutions/FA
 2/17/21  Illumina, Inc.                    10-K        1/03/21  102:13M
 2/05/21  Illumina, Inc.                    8-K:1,9     2/04/21   11:202K                                   Cravath Swaine & … 01/FA
10/30/20  Illumina, Inc.                    10-Q        9/27/20   67:7.5M
 9/21/20  Illumina, Inc.                    8-K:1,8,9   9/20/20   14:2.2M                                   Cravath Swaine & … 01/FA
 8/07/20  Illumina, Inc.                    10-Q        6/28/20   68:8.3M
 2/11/20  Illumina, Inc.                    10-K       12/29/19  109:16M
 1/02/20  Illumina, Inc.                    8-K:1,7,9   1/02/20   14:223K
10/25/19  Illumina, Inc.                    10-Q        9/29/19   74:8.8M
 9/26/19  Illumina, Inc.                    8-K:1,9     9/25/19   13:218K
 7/31/19  Illumina, Inc.                    10-Q        6/30/19   74:8.2M
11/05/18  Illumina, Inc.                    8-K:1,5,8,910/31/18    4:705K
 8/21/18  Illumina, Inc.                    8-K:1,2,3,8 8/21/18    2:659K                                   Donnelley … Solutions/FA
 4/25/18  Illumina, Inc.                    10-Q        4/01/18   71:5.4M
 2/13/18  Illumina, Inc.                    10-K       12/31/17  113:13M
 2/14/17  Illumina, Inc.                    10-K        1/01/17  119:13M
 3/02/16  Illumina, Inc.                    10-K        1/03/16  114:12M
 7/31/15  Illumina, Inc.                    10-Q        6/28/15   56:5.4M
 2/18/15  Illumina, Inc.                    10-K       12/28/14  107:51M
10/29/14  Illumina, Inc.                    10-Q        9/28/14   63:7.2M
 6/11/14  Illumina, Inc.                    8-K:1,2,3,8 6/05/14    3:1M                                     Donnelley … Solutions/FA
 5/03/12  Illumina, Inc.                    10-Q        4/01/12   66:7M
 2/07/12  Illumina, Inc.                    SC 14D9                5:1M   Illumina, Inc.                    Donnelley … Solutions/FA
 2/26/10  Illumina, Inc.                    10-K        1/03/10   11:1.6M                                   Donnelley … Solutions/FA
 2/26/09  Illumina, Inc.                    10-K       12/28/08   15:1.7M                                   Bowne - BSD/FA
 7/25/08  Illumina, Inc.                    10-Q        6/29/08   10:634K                                   Bowne - BSD/FA
11/26/07  Illumina, Inc.                    8-K:9      11/26/07    6:450K                                   Bowne - BSD/FA
 5/03/07  Illumina, Inc.                    10-Q        4/01/07    8:2.6M                                   Bowne - BSD/FA
 7/03/00  Illumina, Inc.                    S-1/A                 14:614K                                   Donnelley Fin’l S… 13/FA
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