Rosenthal Richard Jay · 3 · Symyx Technologies Inc · For 12/10/07 · EX-24.3_215288

Filed On 12/12/07 6:17pm ET   ·   SEC File 0-27765   ·   Accession Number 1209191-7-69467

Initial Statement of Beneficial Ownership of Securities   ·   Form 3
Filing Table of Contents

Document/Exhibit                   Description                      Pages   Size 

 1: 3           Form 3 Submission                                    XML      4K 
 2: EX-24.3_215288  Poa Document                                       1      6K 

EX-24.3_215288   ·   Poa Document

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POWER OF ATTORNEY                                                               
Know all by these presents, that the undersigned hereby constitutes and appoints
each of Rex Jackson, Andrew Powell and Gordon Ho, signing individually, the     
undersigned's true and lawful attorneys-in fact and agents to:                  
(1) execute for and on behalf of the undersigned, an officer, director or holder
of 10% of more of a registered class of securities of Symyx Technologies, Inc.  
(the "Company"), Forms 3, 4 and 5 in accordance with Section 16(a) of the       
Securities Exchange Act of 1934, as amended (the "Exchange Act") and the rules  
thereunder;                                                                     
(2) do and perform any and all acts for and on behalf of the undersigned that   
may be necessary or desirable to complete and execute such Form 3, 4 or 5,      
complete and execute any amendment or amendments thereto, and timely file such  
forms or amendments with the United States Securities and Exchange Commission   
and any stock exchange or similar authority; and                                
(3) take any other action of any nature whatsoever in connection with the       
foregoing which, in the opinion of such attorney-in-fact, may be of benefit, in 
the best interest of, or legally required by, the undersigned, it being         
understood that the documents executed by such attorney-in-fact on behalf of the
undersigned pursuant to this Power of Attorney shall be in such form and shall  
contain such terms and conditions as such attorney-in-fact may approve in such  
attorney-in-fact's discretion.                                                  
The undersigned hereby grants to each such attorney-in-fact full power and      
authority to do and perform any and every act and thing whatsoever requisite,   
necessary, or proper to be done in the exercise of any of the rights and powers 
herein granted, as fully to all intents and purposes as the undersigned might or
could do if personally present, with full power of substitution or revocation,  
hereby ratifying and confirming all that such attorney-in-fact, or such         
attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be  
done by virtue of this power of attorney and the rights and powers herein       
granted.  The undersigned acknowledges that the foregoing attorneys-in-fact, in 
serving in such capacity at the request of the undersigned, are not assuming,   
nor is the Company assuming, any of the undersigned's responsibilities to comply
with Section 16 of the Exchange Act.                                            
This Power of Attorney shall remain in full force and effect until the earliest 
to occur of (a) the undersigned is no longer required to file Forms 3, 4 and 5  
with respect to the undersigned's holdings of and transactions in securities    
issued by the Company, (b) revocation by the undersigned in a signed writing    
delivered to the foregoing attorneys-in-fact or (c) as to any attorney-in-fact  
individually, until such attorney-in-fact shall no longer be employed by the    
Company.                                                                        
IN WITNESS WHEREOF, the undersigned has cause this Power of Attorney to be      
executed as of this 11th day of December, 2007.                                 

/s/Richard Jay Rosenthal                                                        
Richard Jay Rosenthal