As Of                Filer                Filing    For·On·As Docs:Size              Issuer               Agent

 6/17/16  Morgan Stanley Inst’l Fund Trust  497         6/17/16    1:23K                                    Merrill Corp-MD/FA
          → Short Duration Income Portfolio ⇒ Class R6 (MSDSX)

Document/Exhibit                   Description                      Pages   Size 

 1: 497         Definitive Material                                 HTML     19K 

Statement of Additional Information Supplement

June 17, 2016

Morgan Stanley Institutional Fund Trust

Supplement dated June 17, 2016 to the Morgan Stanley Institutional Fund Trust Statement of Additional Information dated January 11, 2016

Short Duration Income Portfolio (Class IS)

The table in the section entitled "Disclosure of Portfolio Holdings" in the Statement of Additional Information is hereby deleted and replaced with the following:

Name

Information Disclosed

Frequency(1)

Lag Time

Service Providers

Institutional Shareholder Services*

Complete portfolio holdings

Daily basis

End of Day

State Street Bank and Trust Company*

Complete portfolio holdings

Daily basis

(2)

State Street Global Markets LLC

Complete portfolio holdings

Monthly basis

Approximately 10 business days

BlackRock Financial Management Inc.*

Complete portfolio holdings

Daily basis

(2)

Eze Software Group

Complete portfolio holdings

Monthly basis holdings

Approximately 10 business days

FX Transparency LLC

Complete portfolio holdings

Quarterly basis

Approximately three-four weeks after quarter end

KellyCo Marketing

Complete portfolio holdings

Monthly basis and Quarterly basis

(2)

RR Donnelley Inc.

Complete portfolio holdings

Monthly basis and Quarterly basis

(2)

Fund Rating Agencies

Broadridge*

Top ten and complete portfolio holdings

Daily basis

End of Day

Portfolio Analytics Providers

FactSet Research Systems, Inc.*

Complete portfolio holdings

Daily basis

End of Day

ITG Analytics Inc.

Complete portfolio holdings

Daily basis

One Day

*  This entity has agreed to maintain Fund non-public portfolio holdings information in confidence and not to trade portfolio securities based on the non-public portfolio holdings information.

⁽¹⁾  Dissemination of portfolio holdings information to entities listed above may occur less frequently than indicated (or not at all).

⁽²⁾  Information will typically be provided on a real time basis or as soon thereafter as possible.

The second paragraph under the section of the Statement of Additional Information entitled "Account Policies and Features—Valuation of Shares" is hereby deleted and replaced with the following:

In the calculation of the Portfolio's NAV: (1) an equity portfolio security listed or traded on an exchange is valued at its latest reported sale price (or at the exchange official closing price if such exchange reports an official closing price), and if there were no sales on a given day and if there is no official exchange closing price for that day, the security is valued at the mean between the last reported bid and asked prices if such bid and asked prices are available on the relevant exchanges; and (2) all other equity portfolio securities for which OTC market quotations are readily available are valued at the latest reported sale price (or at the market official closing price if such market reports an official closing price), and if there was no trading in the security on a given day and if there is no official closing price from the relevant markets for that day, the security is valued at the mean between the last reported bid and asked prices if such bid and asked prices are available on the relevant markets. Listed securities not traded on the valuation date with no reported bid and asked prices available on the exchange are valued at the mean between the current bid and asked prices obtained from one or more reputable brokers or dealers. An unlisted equity security that does not trade on the valuation date and for which bid and asked prices from the relevant markets are unavailable is valued at the mean between the current bid and asked prices obtained from one or more reputable brokers or dealers. In cases where a security is traded on more than one exchange, the security is valued on the exchange designated as the primary market. When market quotations are not readily available, including circumstances under which it is determined by the Adviser and/or Sub-Adviser, as applicable, that the closing price, the last sale price or the mean between the last reported bid and asked prices are not reflective of a security's market value, portfolio securities are valued at their fair value as

determined in good faith under procedures established by and under the general supervision of the Fund's Board. For valuation purposes, quotations of foreign portfolio securities, other assets and liabilities and forward contracts stated in foreign currency are translated into U.S. dollar equivalents at the prevailing market rates prior to the close of the NYSE.

Please retain this supplement for future reference.