As Of                Filer                Filing    For·On·As Docs:Size              Issuer               Agent

12/04/17  Morgan Stanley Inst’l Fund Trust  497        12/04/17    1:5K                                     Merrill Corp-MD/FA
          → Ultra Short Income Portfolio ⇒ Class A (MUAIX) — Class IR (MULSX) — Institutional Class (MUIIX)

Document/Exhibit                   Description                      Pages   Size 

 1: 497         Definitive Material                                 HTML      5K 

Prospectus Supplement

December 4, 2017

Morgan Stanley Institutional Fund Trust

Supplement dated December 4, 2017 to the Morgan Stanley Institutional Fund Trust Prospectus dated January 31, 2017

Ultra-Short Income Portfolio

The first sentence of the section of the Prospectus entitled "Portfolio Summary—Payments to Broker-Dealers and Other Financial Intermediaries" is hereby deleted and replaced with the following:

If you purchase shares of the Portfolio through a Financial Intermediary (such as a bank), the Adviser and/or the Distributor may pay the Financial Intermediary for the sale of Portfolio shares and related services.

Please retain this supplement for future reference.

  IFTUSIPROSPT 12/17