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| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXSharesBasedCompensationUnrecognizedCompensation_40" xlink:type="arc" order="5"/> |
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| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_ClassesOfLiabilitiesAxis" xlink:label="loc_ifrs-fullClassesOfLiabilitiesAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesTable" xlink:to="loc_ifrs-fullClassesOfLiabilitiesAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_LiabilitiesMember" xlink:label="loc_ifrs-fullLiabilitiesMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullClassesOfLiabilitiesAxis" xlink:to="loc_ifrs-fullLiabilitiesMember" xlink:type="arc" order="20"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_LiabilitiesMember" xlink:label="loc_ifrs-fullLiabilitiesMember_10"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xbrldt:contextElement="segment" xlink:from="loc_ifrs-fullClassesOfLiabilitiesAxis" xlink:to="loc_ifrs-fullLiabilitiesMember_10" xlink:type="arc" order="30"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_WarrantsMember" xlink:label="loc_NYMXWarrantsMember_0"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullLiabilitiesMember" xlink:to="loc_NYMXWarrantsMember_0" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_ClasseOfWarrantOrRightsOutstanding" xlink:label="loc_NYMXClasseOfWarrantOrRightsOutstanding_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXClasseOfWarrantOrRightsOutstanding_40" xlink:type="arc" order="0"/> |
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| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWarrantExercisedOutstandingShares_40" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_WarrantGrantedOutstandingShares" xlink:label="loc_NYMXWarrantGrantedOutstandingShares_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWarrantGrantedOutstandingShares_40" xlink:type="arc" order="2"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_WarrantExpiredOutstandingShares" xlink:label="loc_NYMXWarrantExpiredOutstandingShares_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWarrantExpiredOutstandingShares_40" xlink:type="arc" order="3"/> |
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| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWarrantCancelledOutstandingShares_40" xlink:type="arc" order="4"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_WarrantOutstandingWeightedAverageExercisePrice" xlink:label="loc_NYMXWarrantOutstandingWeightedAverageExercisePrice_40"/> |
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| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWarrantExercisedWeightedAverageExercisePrice_40" xlink:type="arc" order="8"/> |
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| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWarrantsExpiredWeightedAverageExercisePrice_40" xlink:type="arc" order="10"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_WarrantCancelledWeightedAverageExercisePrice" xlink:label="loc_NYMXWarrantCancelledWeightedAverageExercisePrice_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWarrantCancelledWeightedAverageExercisePrice_40" xlink:type="arc" order="11"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_WeightedAverageRemainingContractualLifeInYear" xlink:label="loc_NYMXWeightedAverageRemainingContractualLifeInYear_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWeightedAverageRemainingContractualLifeInYear_40" xlink:type="arc" order="14"/> |
| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_WeightedAverageRemainingContractualLifeGrantedInYear" xlink:label="loc_NYMXWeightedAverageRemainingContractualLifeGrantedInYear_40"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfFairValueMeasurementOfLiabilitiesLineItems" xlink:to="loc_NYMXWeightedAverageRemainingContractualLifeGrantedInYear_40" xlink:type="arc" order="15"/> |
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| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:label="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable"/> |
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| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_TypesOfContractsAxis" xlink:label="loc_ifrs-fullTypesOfContractsAxis"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesTable" xlink:to="loc_ifrs-fullTypesOfContractsAxis" xlink:type="arc" order="1"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_TypesOfContractsMember" xlink:label="loc_ifrs-fullTypesOfContractsMember"/> |
| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_ifrs-fullTypesOfContractsAxis" xlink:to="loc_ifrs-fullTypesOfContractsMember" xlink:type="arc" order="20"/> |
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| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_PrivatePlacementsMember" xlink:label="loc_NYMXPrivatePlacementsMember_0"/> |
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| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_PlacementAgentMember" xlink:label="loc_NYMXPlacementAgentMember_40"/> |
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| | <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_ifrs-fullDisclosureOfTransactionsBetweenRelatedPartiesLineItems" xlink:to="loc_NYMXNumberOfWarrantsIssued_70" xlink:type="arc" order="0"/> |
| | <link:loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2018-03-16/full_ifrs/full_ifrs-cor_2018-03-16.xsd#ifrs-full_ParValuePerShare" xlink:label="loc_ifrs-fullParValuePerShare_70"/> |
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| | <link:loc xlink:type="locator" xlink:href="nymx-20181231.xsd#NYMX_ProceesFromIssuanceOfWarrants" xlink:label="loc_NYMXProceesFromIssuanceOfWarrants_70"/> |
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