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| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_WeightedAverageNumberOfCommonShareOutstandingBasicAndDiluted" xlink:label="opk_WeightedAverageNumberOfCommonShareOutstandingBasicAndDiluted"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpenseAbstract" xlink:label="loc_OtherNonoperatingIncomeExpenseAbstract"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_RestructuringCharges"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_OperatingExpensesAbstract" xlink:to="loc_RestructuringCharges" order="9.25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicAndDilutedShare" xlink:label="us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicAndDilutedShare"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_NetCashProvidedByUsedInOperatingActivitiesAbstract"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="loc_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" order="3.1" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_DepreciationDepletionAndAmortization"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AccretionExpense" xlink:label="loc_AccretionExpense"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_ShareBasedCompensation"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_GainLossOnInvestments" xlink:label="loc_GainLossOnInvestments"/> |
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| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ProvisionRecoveryOfForDoubtfulAccounts" xlink:label="opk_ProvisionRecoveryOfForDoubtfulAccounts"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:label="loc_IncreaseDecreaseInAccruedLiabilities"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_ProceedsFromIssuanceOfCommonStock"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_SupplementalCashFlowInformationAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementOfCashFlowsAbstract" xlink:to="loc_SupplementalCashFlowInformationAbstract" order="42.1" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_InterestPaid" xlink:label="loc_InterestPaid"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SupplementalCashFlowInformationAbstract" xlink:to="loc_InterestPaid" order="43.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_IncomeTaxesPaidNet" xlink:label="loc_IncomeTaxesPaidNet"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SupplementalCashFlowInformationAbstract" xlink:to="loc_IncomeTaxesPaidNet" order="44.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations" xlink:label="loc_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="loc_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations" order="11.05" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations" xlink:label="loc_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="loc_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations" order="7.075" use="optional" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_PaymentsToAcquireProductiveAssets" xlink:label="loc_PaymentsToAcquireProductiveAssets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="loc_PaymentsToAcquireProductiveAssets" order="24.75" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:label="loc_PaymentsToAcquireEquityMethodInvestments"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="loc_PaymentsToAcquireEquityMethodInvestments" order="24.25" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_MaturitiesOfShortTermMarketableSecurities" xlink:label="opk_MaturitiesOfShortTermMarketableSecurities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="opk_MaturitiesOfShortTermMarketableSecurities" order="23.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_PaymentsToAcquireMarketableSecurities" xlink:label="loc_PaymentsToAcquireMarketableSecurities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="loc_PaymentsToAcquireMarketableSecurities" order="22" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:label="loc_PaymentsToAcquireBusinessesNetOfCashAcquired"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="loc_PaymentsToAcquireBusinessesNetOfCashAcquired" order="10.5" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ForeignCurrencyMeasurement" xlink:label="opk_ForeignCurrencyMeasurement"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_IncreaseDecreaseInOperatingCapitalAbstract" xlink:to="opk_ForeignCurrencyMeasurement" order="15.25" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RevenueFromReceiptOfEquity" xlink:label="opk_RevenueFromReceiptOfEquity"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="opk_RevenueFromReceiptOfEquity" order="9.275" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax" xlink:label="loc_IncomeLossFromDiscontinuedOperationsNetOfTax"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="loc_IncomeLossFromDiscontinuedOperationsNetOfTax" order="1.25" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_NetIncomeLoss"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="loc_NetIncomeLoss" order="0.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableforsaleSecuritiesTransfersToTradingGainsLossesExcludingOtherThanTemporaryImpairments" xlink:label="loc_AvailableforsaleSecuritiesTransfersToTradingGainsLossesExcludingOtherThanTemporaryImpairments"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="loc_AvailableforsaleSecuritiesTransfersToTradingGainsLossesExcludingOtherThanTemporaryImpairments" order="9.739062" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:label="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementOfCashFlowsAbstract" xlink:to="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" order="62.1" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_IssuanceOfCommonStockToAcquireEntity" xlink:label="opk_IssuanceOfCommonStockToAcquireEntity"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:to="opk_IssuanceOfCommonStockToAcquireEntity" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CommonStockWarrantsNetExercised" xlink:label="opk_CommonStockWarrantsNetExercised"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:to="opk_CommonStockWarrantsNetExercised" order="15" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FairValueOfContingentConsiderationPeriodIncrease" xlink:label="opk_FairValueOfContingentConsiderationPeriodIncrease"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="opk_FairValueOfContingentConsiderationPeriodIncrease" order="9.777734" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/BusinessAndOrganization" xlink:title="0201 - Disclosure - Business and Organization"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:label="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/SummaryOfSignificantAccountingPolicies" xlink:title="0202 - Disclosure - Summary of Significant Accounting Policies"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_AccountingPoliciesAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_SignificantAccountingPoliciesTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_SignificantAccountingPoliciesTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/LossPerShare" xlink:title="0203 - Disclosure - Loss Per Share"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_EarningsPerShareAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="loc_EarningsPerShareTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_EarningsPerShareAbstract" xlink:to="loc_EarningsPerShareTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/CompositionOfCertainFinancialStatementCaptions" xlink:title="0204 - Disclosure - Composition of Certain Financial Statement Captions"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SupplementalBalanceSheetDisclosuresTextBlock" xlink:label="loc_SupplementalBalanceSheetDisclosuresTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="loc_SupplementalBalanceSheetDisclosuresTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/DiscontinuedOperations" xlink:title="0206 - Disclosure - Discontinued Operations"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_DiscontinuedOperationsAndDisposalGroupsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock" xlink:label="loc_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:to="loc_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/FairValueMeasurements" xlink:title="0207 - Disclosure - Fair Value Measurements"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_FairValueDisclosuresAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock" xlink:label="loc_FairValueDisclosuresTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="loc_FairValueDisclosuresTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/DerivativeContracts" xlink:title="0208 - Disclosure - Derivative Contracts"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:label="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:to="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/RelatedPartyTransactions" xlink:title="0209 - Disclosure - Related Party Transactions"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="loc_RelatedPartyTransactionsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyTransactionsDisclosureTextBlock" xlink:label="loc_RelatedPartyTransactionsDisclosureTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyTransactionsAbstract" xlink:to="loc_RelatedPartyTransactionsDisclosureTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/CommitmentsAndContingencies" xlink:title="0210 - Disclosure - Commitments and Contingencies"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_CommitmentsAndContingenciesDisclosureAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_CommitmentsAndContingenciesDisclosureTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_CommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_CommitmentsAndContingenciesDisclosureTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/Segments" xlink:title="0211 - Disclosure - Segments"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_SegmentReportingAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentReportingDisclosureTextBlock" xlink:label="loc_SegmentReportingDisclosureTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentReportingAbstract" xlink:to="loc_SegmentReportingDisclosureTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/SubsequentEvents" xlink:title="0212 - Disclosure - Subsequent Events"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="loc_SubsequentEventsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SubsequentEventsTextBlock" xlink:label="loc_SubsequentEventsTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SubsequentEventsAbstract" xlink:to="loc_SubsequentEventsTextBlock" order="1.0" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:title="0402 - Disclosure - Summary of Significant Accounting Policies (Policies)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_AccountingPoliciesAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="loc_BasisOfAccountingPolicyPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_BasisOfAccountingPolicyPolicyTextBlock" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="loc_ConsolidationPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_ConsolidationPolicyTextBlock" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="loc_UseOfEstimates"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_UseOfEstimates" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:label="loc_CashAndCashEquivalentsPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_CashAndCashEquivalentsPolicyTextBlock" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_MarketableSecuritiesPolicy" xlink:label="loc_MarketableSecuritiesPolicy"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_MarketableSecuritiesPolicy" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RevenueRecognitionPolicyTextBlock" xlink:label="loc_RevenueRecognitionPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_RevenueRecognitionPolicyTextBlock" order="140" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativesPolicyTextBlock" xlink:label="loc_DerivativesPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_DerivativesPolicyTextBlock" order="160" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_GuaranteesIndemnificationsAndWarrantiesPolicies" xlink:label="loc_GuaranteesIndemnificationsAndWarrantiesPolicies"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_GuaranteesIndemnificationsAndWarrantiesPolicies" order="180" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock" xlink:label="loc_SegmentReportingPolicyPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_SegmentReportingPolicyPolicyTextBlock" order="220" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CompensationRelatedCostsPolicyTextBlock" xlink:label="loc_CompensationRelatedCostsPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_CompensationRelatedCostsPolicyTextBlock" order="240" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_NewAccountingPronouncementsPolicyPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_NewAccountingPronouncementsPolicyPolicyTextBlock" order="260" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AllowanceForDoubtfulAccountsPolicyTextBlock" xlink:label="opk_AllowanceForDoubtfulAccountsPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="opk_AllowanceForDoubtfulAccountsPolicyTextBlock" order="190" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_PriorPeriodReclassificationAdjustmentDescription" xlink:label="loc_PriorPeriodReclassificationAdjustmentDescription"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="loc_PriorPeriodReclassificationAdjustmentDescription" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_InventoryPolicyTextBlock" xlink:label="us-gaap_InventoryPolicyTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountingPoliciesAbstract" xlink:to="us-gaap_InventoryPolicyTextBlock" order="120" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/LossPerShareDetailsTextual" xlink:title="0603 - Disclosure - Loss Per Share (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_EarningsPerShareAbstract"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_LossPerShareTextualAbstract" xlink:label="opk_LossPerShareTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_EarningsPerShareAbstract" xlink:to="opk_LossPerShareTextualAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_LossPerShareTextualAbstract" xlink:to="loc_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfCommonSharesToBeIssuedOnConversionOfPreferredStock" xlink:label="opk_NumberOfCommonSharesToBeIssuedOnConversionOfPreferredStock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_LossPerShareTextualAbstract" xlink:to="opk_NumberOfCommonSharesToBeIssuedOnConversionOfPreferredStock" order="38.75" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CommonStockIssuedForStockOptionAndWarrantsExercises" xlink:label="opk_CommonStockIssuedForStockOptionAndWarrantsExercises"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_LossPerShareTextualAbstract" xlink:to="opk_CommonStockIssuedForStockOptionAndWarrantsExercises" order="58.75" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/DiscontinuedOperationsTables" xlink:title="0506 - Disclosure - Discontinued Operations (Tables)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_DiscontinuedOperationsAndDisposalGroupsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DisposalGroupIncludingDiscontinuedOperationClassifiedBalanceSheetDisclosuresTableTextBlock" xlink:label="opk_DisposalGroupIncludingDiscontinuedOperationClassifiedBalanceSheetDisclosuresTableTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:to="opk_DisposalGroupIncludingDiscontinuedOperationClassifiedBalanceSheetDisclosuresTableTextBlock" order="5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DisposalGroupNotDiscontinuedOperationIncomeStatementDisclosuresTableTextBlock" xlink:label="opk_DisposalGroupNotDiscontinuedOperationIncomeStatementDisclosuresTableTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:to="opk_DisposalGroupNotDiscontinuedOperationIncomeStatementDisclosuresTableTextBlock" order="12.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/FairValueMeasurementsTables" xlink:title="0507 - Disclosure - Fair Value Measurements (Tables)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_FairValueDisclosuresAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="loc_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="loc_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ReconcilesBeginningAndEndingBalancesOfLevelThreeAssetsAndLiabilitiesTableTextBlock" xlink:label="opk_ReconcilesBeginningAndEndingBalancesOfLevelThreeAssetsAndLiabilitiesTableTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="opk_ReconcilesBeginningAndEndingBalancesOfLevelThreeAssetsAndLiabilitiesTableTextBlock" order="50" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_TradingSecuritiesAndCertainTradingAssetsTextBlock" xlink:label="loc_TradingSecuritiesAndCertainTradingAssetsTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="loc_TradingSecuritiesAndCertainTradingAssetsTextBlock" order="5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/DerivativeContractsTables" xlink:title="0508 - Disclosure - Derivative Contracts (Tables)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfForeignExchangeContractsStatementOfFinancialPositionTableTextBlock" xlink:label="loc_ScheduleOfForeignExchangeContractsStatementOfFinancialPositionTableTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:to="loc_ScheduleOfForeignExchangeContractsStatementOfFinancialPositionTableTextBlock" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/SegmentsTables" xlink:title="0511 - Disclosure - Segments (Tables)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_SegmentReportingAbstract"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ScheduleOfInformationRegardingProductRevenueByGeographicAreaTableTextBlock" xlink:label="opk_ScheduleOfInformationRegardingProductRevenueByGeographicAreaTableTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentReportingAbstract" xlink:to="opk_ScheduleOfInformationRegardingProductRevenueByGeographicAreaTableTextBlock" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/AcquisitionAndInvestmentsDetails" xlink:title="0605 - Disclosure - Acquisitions, Investments, and Licenses (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_BusinessCombinationsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessCombinationsAbstract" xlink:to="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_BusinessAcquisitionAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_BusinessAcquisitionAxis" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_BusinessAcquisitionAcquireeDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAxis" xlink:to="loc_BusinessAcquisitionAcquireeDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_BusinessAcquisitionLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_BusinessAcquisitionLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionLineItems" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice" order="240" use="optional" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionContingentConsiderationAtFairValue" xlink:label="loc_BusinessAcquisitionContingentConsiderationAtFairValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionContingentConsiderationAtFairValue" order="220" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccountsPayableAndAccruedExpenses" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccountsPayableAndAccruedExpenses"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccountsPayableAndAccruedExpenses" order="140" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationGoodwillAmount" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationGoodwillAmount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationGoodwillAmount" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetsOtherThanGoodwill" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetsOtherThanGoodwill"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetsOtherThanGoodwill" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationCurrentAssets" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationCurrentAssets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationCurrentAssets" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationPropertyPlantAndEquipment" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationPropertyPlantAndEquipment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationPropertyPlantAndEquipment" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FinetechAcquisitionMember" xlink:label="opk_FinetechAcquisitionMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_FinetechAcquisitionMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationCustomerRelationships" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationCustomerRelationships"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationCustomerRelationships" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationTradeName" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationTradeName"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationTradeName" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationOtherAssets" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationOtherAssets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationOtherAssets" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationDeferredIncomeTaxesAssetLiabilityNet" xlink:label="us-gaap_BusinessAcquisitionPurchasePriceAllocationDeferredIncomeTaxesAssetLiabilityNet_3"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="us-gaap_BusinessAcquisitionPurchasePriceAllocationDeferredIncomeTaxesAssetLiabilityNet_3" order="160" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AramaLaboratoriesAcquisitionMember" xlink:label="opk_AramaLaboratoriesAcquisitionMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_AramaLaboratoriesAcquisitionMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationProductRegistrations" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationProductRegistrations"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationProductRegistrations" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationNotesPayableAndLongTermDebt" xlink:label="us-gaap_BusinessAcquisitionPurchasePriceAllocationNotesPayableAndLongTermDebt"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="us-gaap_BusinessAcquisitionPurchasePriceAllocationNotesPayableAndLongTermDebt" order="200" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationDeferredPayment" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationDeferredPayment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationDeferredPayment" order="180" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationCovenantsNotToCompete" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationCovenantsNotToCompete_2"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationCovenantsNotToCompete_2" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationTechnology" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationTechnology"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationTechnology" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceInProcessResearchAndDevelopmentExpensed" xlink:label="opk_BusinessAcquisitionPurchasePriceInProcessResearchAndDevelopmentExpensed"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_BusinessAcquisitionPurchasePriceAllocationIntangibleAssetAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceInProcessResearchAndDevelopmentExpensed" order="35" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/AcquisitionAndInvestmentsDetails1" xlink:title="06052 - Disclosure - Acquisitions, Investments, and Licenses (Details 2)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_BusinessCombinationsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessCombinationsAbstract" xlink:to="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis" xlink:label="loc_VariableInterestEntitiesByClassificationOfEntityAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:to="loc_VariableInterestEntitiesByClassificationOfEntityAxis" order="10" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ClassificationOfVariableInterestEntityDomain" xlink:label="loc_ClassificationOfVariableInterestEntityDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntitiesByClassificationOfEntityAxis" xlink:to="loc_ClassificationOfVariableInterestEntityDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntityPrimaryBeneficiaryMember" xlink:label="loc_VariableInterestEntityPrimaryBeneficiaryMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ClassificationOfVariableInterestEntityDomain" xlink:to="loc_VariableInterestEntityPrimaryBeneficiaryMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CocrystalMember" xlink:label="opk_CocrystalMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_CocrystalMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TesaroMember" xlink:label="opk_TesaroMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_TesaroMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_StatementLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:to="loc_StatementLineItems" order="15" use="optional" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_UnrealizedGainLossOnInvestmentsAbstract" xlink:label="loc_UnrealizedGainLossOnInvestmentsAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementLineItems" xlink:to="loc_UnrealizedGainLossOnInvestmentsAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntityEntityMaximumLossExposureAmount" xlink:label="loc_VariableInterestEntityEntityMaximumLossExposureAmount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="loc_VariableInterestEntityEntityMaximumLossExposureAmount" order="2.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_VariableInterestEntityEntityAccumulatedLossesInInvestees" xlink:label="opk_VariableInterestEntityEntityAccumulatedLossesInInvestees"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="opk_VariableInterestEntityEntityAccumulatedLossesInInvestees" order="7.5" use="optional" preferredLabel="http://xbrl.us/us-gaap/role/label/negated" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_SorrentoMember" xlink:label="opk_SorrentoMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_SorrentoMember" order="50" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BiozoneMember" xlink:label="opk_BiozoneMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_BiozoneMember" order="70" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestmentUnderlyingEquityInNetAssets" xlink:label="loc_EquityMethodInvestmentUnderlyingEquityInNetAssets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="loc_EquityMethodInvestmentUnderlyingEquityInNetAssets" order="6.25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableForSaleSecuritiesEquitySecurities" xlink:label="loc_AvailableForSaleSecuritiesEquitySecurities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="loc_AvailableForSaleSecuritiesEquitySecurities" order="7.8125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_EquityInvestmentYear" xlink:label="opk_EquityInvestmentYear"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="opk_EquityInvestmentYear" order="1.25" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_VariableInterestEntityEntityAccountingMethod" xlink:label="opk_VariableInterestEntityEntityAccountingMethod"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="opk_VariableInterestEntityEntityAccountingMethod" order="1.875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:label="loc_EquityMethodInvestmentOwnershipPercentage"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="loc_EquityMethodInvestmentOwnershipPercentage" order="2.1875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_VariableInterestEntityEntityMaximumNetLossExposureAmount" xlink:label="opk_VariableInterestEntityEntityMaximumNetLossExposureAmount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="opk_VariableInterestEntityEntityMaximumNetLossExposureAmount" order="7.65625" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ChromaDexMember" xlink:label="opk_ChromaDexMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_ChromaDexMember" order="75" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_UnrealizedGainOnInvestmentsOptionsAndWarrants" xlink:label="opk_UnrealizedGainOnInvestmentsOptionsAndWarrants"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="opk_UnrealizedGainOnInvestmentsOptionsAndWarrants" order="7.6757815" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NeovascMember" xlink:label="opk_NeovascMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_NeovascMember" order="45" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FabrusMember" xlink:label="opk_FabrusMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_FabrusMember" order="47.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableForSaleSecuritiesCurrent" xlink:label="us-gaap_AvailableForSaleSecuritiesCurrent"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_UnrealizedGainLossOnInvestmentsAbstract" xlink:to="us-gaap_AvailableForSaleSecuritiesCurrent" order="7.744141" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NeovascOptionsMember" xlink:label="opk_NeovascOptionsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_NeovascOptionsMember" order="77.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BiozonePharmaceuticalsIncMember" xlink:label="opk_BiozonePharmaceuticalsIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_BiozonePharmaceuticalsIncMember" order="72.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/AcquisitionAndInvestmentsDetailsTextual" xlink:title="06053 - Disclosure - Acquisitions, Investments, and Licenses (Details Textual)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_BusinessCombinationsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessCombinationsAbstract" xlink:to="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntityPrimaryBeneficiaryMember" xlink:label="loc_VariableInterestEntityPrimaryBeneficiaryMember"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_BusinessAcquisitionLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_BusinessAcquisitionLineItems" order="120" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AcquisitionAndInvestmentsTextualAbstract" xlink:label="opk_AcquisitionAndInvestmentsTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionLineItems" xlink:to="opk_AcquisitionAndInvestmentsTextualAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" order="860" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_RelatedPartyTransactionsByRelatedPartyAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_RelatedPartyTransactionsByRelatedPartyAxis" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_RelatedPartyDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyTransactionsByRelatedPartyAxis" xlink:to="loc_RelatedPartyDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_SorrentoMember" xlink:label="opk_SorrentoMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_SorrentoMember" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CocrystalMember" xlink:label="opk_CocrystalMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_CocrystalMember" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FabrusMember" xlink:label="opk_FabrusMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_FabrusMember" order="140" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NeovascMember" xlink:label="opk_NeovascMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_NeovascMember" order="160" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationCurrentAssetsCashAndCashEquivalents" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationCurrentAssetsCashAndCashEquivalents"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationCurrentAssetsCashAndCashEquivalents" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurred" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurred"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurred" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurredPaidAtClosing" xlink:label="opk_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurredPaidAtClosing"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurredPaidAtClosing" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuable" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuable" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuableParValue" xlink:label="opk_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuableParValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuableParValue" order="260" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestments" xlink:label="loc_EquityMethodInvestments"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_EquityMethodInvestments" order="890" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfSharesWarrantsAcquiredInEquityMethodInvestment" xlink:label="opk_NumberOfSharesWarrantsAcquiredInEquityMethodInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_NumberOfSharesWarrantsAcquiredInEquityMethodInvestment" order="340" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ExercisePriceOfWarrantsAcquiredInEquityMethodInvestment" xlink:label="opk_ExercisePriceOfWarrantsAcquiredInEquityMethodInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_ExercisePriceOfWarrantsAcquiredInEquityMethodInvestment" order="380" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FairValueOfWarrantsAcquiredInEquityMethodInvestment" xlink:label="opk_FairValueOfWarrantsAcquiredInEquityMethodInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_FairValueOfWarrantsAcquiredInEquityMethodInvestment" order="400" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGrantDateIntrinsicValue" xlink:label="loc_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGrantDateIntrinsicValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGrantDateIntrinsicValue" order="420" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1" xlink:label="loc_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1" order="440" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGrantDateFairValue" xlink:label="opk_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGrantDateFairValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGrantDateFairValue" order="480" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntityOwnershipPercentage" xlink:label="loc_VariableInterestEntityOwnershipPercentage"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_VariableInterestEntityOwnershipPercentage" order="680" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FinancingForVariableInterestEntities" xlink:label="opk_FinancingForVariableInterestEntities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_FinancingForVariableInterestEntities" order="620" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:label="loc_EquityMethodInvestmentOwnershipPercentage"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_EquityMethodInvestmentOwnershipPercentage" order="540" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_EquityInvestment" xlink:label="opk_EquityInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_EquityInvestment" order="640" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OwnershipPercentageOfVariableInterestEntityByRelatedPartyGroup" xlink:label="opk_OwnershipPercentageOfVariableInterestEntityByRelatedPartyGroup"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_OwnershipPercentageOfVariableInterestEntityByRelatedPartyGroup" order="780" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OwnershipPercentageOfVariablesInterestEntity" xlink:label="opk_OwnershipPercentageOfVariablesInterestEntity"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_OwnershipPercentageOfVariablesInterestEntity" order="820" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" order="60" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_EquityMethodInvesteeNameDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:to="loc_EquityMethodInvesteeNameDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NeovascIncMember" xlink:label="opk_NeovascIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_EquityMethodInvesteeNameDomain" xlink:to="opk_NeovascIncMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis" xlink:label="loc_VariableInterestEntitiesByClassificationOfEntityAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_VariableInterestEntitiesByClassificationOfEntityAxis" order="80" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ClassificationOfVariableInterestEntityDomain" xlink:label="loc_ClassificationOfVariableInterestEntityDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntitiesByClassificationOfEntityAxis" xlink:to="loc_ClassificationOfVariableInterestEntityDomain" order="20" use="optional"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ClassificationOfVariableInterestEntityDomain" xlink:to="loc_VariableInterestEntityPrimaryBeneficiaryMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_SorrentoTherapeuticsIncMember" xlink:label="opk_SorrentoTherapeuticsIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_EquityMethodInvesteeNameDomain" xlink:to="opk_SorrentoTherapeuticsIncMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_GammaTrustMember" xlink:label="opk_GammaTrustMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_GammaTrustMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfCostMethodInvestmentsAxis" xlink:label="loc_ScheduleOfCostMethodInvestmentsAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_ScheduleOfCostMethodInvestmentsAxis" order="100" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:label="loc_MajorTypesOfDebtAndEquitySecuritiesDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfCostMethodInvestmentsAxis" xlink:to="loc_MajorTypesOfDebtAndEquitySecuritiesDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfYearsOverWhichRevenueWillBeRecognized" xlink:label="opk_NumberOfYearsOverWhichRevenueWillBeRecognized"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_NumberOfYearsOverWhichRevenueWillBeRecognized" order="460" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PercentageInBoardOfManagers" xlink:label="opk_PercentageInBoardOfManagers"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_PercentageInBoardOfManagers" order="880" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AcquisitionAndInvestmentsAdditionalTextualAbstract" xlink:label="opk_AcquisitionAndInvestmentsAdditionalTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessCombinationsAbstract" xlink:to="opk_AcquisitionAndInvestmentsAdditionalTextualAbstract" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsAdditionalTextualAbstract" xlink:to="opk_EquityInvestment" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_InvestmentInVariableInterestEntities" xlink:label="opk_InvestmentInVariableInterestEntities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_InvestmentInVariableInterestEntities" order="840" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TesaroMember" xlink:label="opk_TesaroMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:to="opk_TesaroMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionCostOfAcquiredEntityCommonStockIssuedMarketValuePerShare" xlink:label="opk_BusinessAcquisitionCostOfAcquiredEntityCommonStockIssuedMarketValuePerShare"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_BusinessAcquisitionCostOfAcquiredEntityCommonStockIssuedMarketValuePerShare" order="140" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AverageClosingSalesPricePerShareOfCommonStock" xlink:label="opk_AverageClosingSalesPricePerShareOfCommonStock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_AverageClosingSalesPricePerShareOfCommonStock" order="160" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ChromadexCorporationMember" xlink:label="opk_ChromadexCorporationMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_ChromadexCorporationMember" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_WorkingCapitalSurplus" xlink:label="opk_WorkingCapitalSurplus"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_WorkingCapitalSurplus" order="240" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ValueOfStockConsiderationHeldInEscrowAccount" xlink:label="opk_ValueOfStockConsiderationHeldInEscrowAccount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_ValueOfStockConsiderationHeldInEscrowAccount" order="180" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchaseOfCommonStockShares" xlink:label="opk_BusinessAcquisitionPurchaseOfCommonStockShares"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_BusinessAcquisitionPurchaseOfCommonStockShares" order="560" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ProceedsFromIssuanceOfPrivatePlacement" xlink:label="loc_ProceedsFromIssuanceOfPrivatePlacement"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_ProceedsFromIssuanceOfPrivatePlacement" order="720" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BiozonePharmaceuticalsIncMember" xlink:label="opk_BiozonePharmaceuticalsIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_BiozonePharmaceuticalsIncMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationNotesPayableAndLongTermDebt" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationNotesPayableAndLongTermDebt"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationNotesPayableAndLongTermDebt" order="740" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PromissoryNotesMaturityDate" xlink:label="opk_PromissoryNotesMaturityDate"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_PromissoryNotesMaturityDate" order="360" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_WarrantsDuration" xlink:label="opk_WarrantsDuration"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_WarrantsDuration" order="700" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_WarrantsToPurchaseCommonShares" xlink:label="opk_WarrantsToPurchaseCommonShares"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_WarrantsToPurchaseCommonShares" order="760" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_UnrealizedGainOnWarrants" xlink:label="opk_UnrealizedGainOnWarrants"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_UnrealizedGainOnWarrants" order="800" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchaseOfSeriesPreferredStock" xlink:label="opk_BusinessAcquisitionPurchaseOfSeriesPreferredStock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_BusinessAcquisitionPurchaseOfSeriesPreferredStock" order="660" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TevaPharmaceuticalIndustriesLtdMember" xlink:label="opk_TevaPharmaceuticalIndustriesLtdMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_TevaPharmaceuticalIndustriesLtdMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_AdditionalPaidInCapitalCommonStock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_AdditionalPaidInCapitalCommonStock" order="220" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAssets" xlink:label="loc_EquityMethodInvestmentSummarizedFinancialInformationAssets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_EquityMethodInvestmentSummarizedFinancialInformationAssets" order="900" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationLiabilities" xlink:label="loc_EquityMethodInvestmentSummarizedFinancialInformationLiabilities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_EquityMethodInvestmentSummarizedFinancialInformationLiabilities" order="920" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNetIncomeLoss" xlink:label="loc_EquityMethodInvestmentSummarizedFinancialInformationNetIncomeLoss"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_EquityMethodInvestmentSummarizedFinancialInformationNetIncomeLoss" order="940" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_HsiaoAndLernerMember" xlink:label="opk_HsiaoAndLernerMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:to="opk_HsiaoAndLernerMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ClaimAgainstEscrowForUndisclosedLiabilities" xlink:label="opk_ClaimAgainstEscrowForUndisclosedLiabilities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_ClaimAgainstEscrowForUndisclosedLiabilities" order="200" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityCashPaid" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityCashPaid"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityCashPaid" order="35" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts" order="37.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionCostOfAcquiredEntityCashPaidThroughEscrowAccount" xlink:label="opk_BusinessAcquisitionCostOfAcquiredEntityCashPaidThroughEscrowAccount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_BusinessAcquisitionCostOfAcquiredEntityCashPaidThroughEscrowAccount" order="36.25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_UnrealizedGainLossOnDerivatives" xlink:label="loc_UnrealizedGainLossOnDerivatives"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_UnrealizedGainLossOnDerivatives" order="815" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableforsaleSecuritiesGrossUnrealizedGain" xlink:label="loc_AvailableforsaleSecuritiesGrossUnrealizedGain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_AvailableforsaleSecuritiesGrossUnrealizedGain" order="817.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DeferredPaymentToSatisfyIndemnityClaims" xlink:label="opk_DeferredPaymentToSatisfyIndemnityClaims"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_DeferredPaymentToSatisfyIndemnityClaims" order="36.171875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfTradingDays" xlink:label="opk_NumberOfTradingDays"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_NumberOfTradingDays" order="36.2109375" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfAncillaryTransaction" xlink:label="opk_NumberOfAncillaryTransaction"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_NumberOfAncillaryTransaction" order="36.23046875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AncillaryTransactionDetails" xlink:label="opk_AncillaryTransactionDetails"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_AncillaryTransactionDetails" order="36.240234375" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_MinorityInterestOwnershipPercentageByParent" xlink:label="us-gaap_MinorityInterestOwnershipPercentageByParent"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="us-gaap_MinorityInterestOwnershipPercentageByParent" order="36.245115" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_CommonStockSharesIssued"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="loc_CommonStockSharesIssued" order="36.24267" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfSharesIssuedAtClosingDate" xlink:label="opk_NumberOfSharesIssuedAtClosingDate"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_NumberOfSharesIssuedAtClosingDate" order="36.24389" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfSharesIssuedUponAchievingCertainMilestone" xlink:label="opk_NumberOfSharesIssuedUponAchievingCertainMilestone"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_NumberOfSharesIssuedUponAchievingCertainMilestone" order="36.2445" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_MinorityInterestOwnershipPercentageByNoncontrollingOwners" xlink:label="us-gaap_MinorityInterestOwnershipPercentageByNoncontrollingOwners"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="us-gaap_MinorityInterestOwnershipPercentageByNoncontrollingOwners" order="36.247555" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AmountPayableOnCashOrSharesOnAchievingMilestones" xlink:label="opk_AmountPayableOnCashOrSharesOnAchievingMilestones"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_AmountPayableOnCashOrSharesOnAchievingMilestones" order="36.2487775" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BiozonePharmaceuticalsWarrantsExercised" xlink:label="opk_BiozonePharmaceuticalsWarrantsExercised"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_BiozonePharmaceuticalsWarrantsExercised" order="710" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_TesaroMember" order="180" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AdditionalAmountPaidForLegalRegistration" xlink:label="opk_AdditionalAmountPaidForLegalRegistration"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_AdditionalAmountPaidForLegalRegistration" order="960" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PortionOfBusinessAcquisitionCostOfAcquiredEntityCashPaid" xlink:label="opk_PortionOfBusinessAcquisitionCostOfAcquiredEntityCashPaid"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_PortionOfBusinessAcquisitionCostOfAcquiredEntityCashPaid" order="35.3125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PortionOfDeferredPaymentPaidAtOurOptionInCashOrShares" xlink:label="opk_PortionOfDeferredPaymentPaidAtOurOptionInCashOrShares"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_PortionOfDeferredPaymentPaidAtOurOptionInCashOrShares" order="35.46875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PortionOfPaidOnFirstAnniversaryOfClosingDate" xlink:label="opk_PortionOfPaidOnFirstAnniversaryOfClosingDate"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_PortionOfPaidOnFirstAnniversaryOfClosingDate" order="35.546875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PortionOfPaidInEighteenMonthsAfterClosingDate" xlink:label="opk_PortionOfPaidInEighteenMonthsAfterClosingDate"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_PortionOfPaidInEighteenMonthsAfterClosingDate" order="36.01563" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PortionOfAmountPayableOnCashOrSharesOnAchievingMilestones" xlink:label="opk_PortionOfAmountPayableOnCashOrSharesOnAchievingMilestones"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_PortionOfAmountPayableOnCashOrSharesOnAchievingMilestones" order="36.248165" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DeferredAcquisitionPaymentsNetOfDiscount" xlink:label="opk_DeferredAcquisitionPaymentsNetOfDiscount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_DeferredAcquisitionPaymentsNetOfDiscount" order="36.0546875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DeferredAcquisitionPaymentsDiscount" xlink:label="opk_DeferredAcquisitionPaymentsDiscount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="opk_DeferredAcquisitionPaymentsDiscount" order="36.07421875" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SharePrice" xlink:label="us-gaap_SharePrice"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_AcquisitionAndInvestmentsTextualAbstract" xlink:to="us-gaap_SharePrice" order="715" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_BusinessAcquisitionAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_BusinessAcquisitionAxis" order="10" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_BusinessAcquisitionAcquireeDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAxis" xlink:to="loc_BusinessAcquisitionAcquireeDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AlsAcquisitionMember" xlink:label="opk_AlsAcquisitionMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_AlsAcquisitionMember" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FinetechAcquisitionMember" xlink:label="opk_FinetechAcquisitionMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_FinetechAcquisitionMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ClarosDiagnosticsMember" xlink:label="opk_ClarosDiagnosticsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_ClarosDiagnosticsMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FarmadietAcquisitionMember" xlink:label="opk_FarmadietAcquisitionMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_FarmadietAcquisitionMember" order="50" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntityPrimaryBeneficiaryMember" xlink:label="us-gaap_VariableInterestEntityPrimaryBeneficiaryMember_2"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="us-gaap_VariableInterestEntityPrimaryBeneficiaryMember_2" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ProductOrServiceAxis" xlink:label="us-gaap_ProductOrServiceAxis"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_ProductsAndServicesDomain"/> |
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| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FabrusLlcMember" xlink:label="opk_FabrusLlcMember"/> |
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| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FabrusAndDrsFrostMember" xlink:label="opk_FabrusAndDrsFrostMember"/> |
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| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CocrystalDiscoveryIncMember" xlink:label="opk_CocrystalDiscoveryIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_VariableInterestEntityPrimaryBeneficiaryMember" xlink:to="opk_CocrystalDiscoveryIncMember" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_InvestmentsMember" xlink:label="loc_InvestmentsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:to="loc_InvestmentsMember" order="5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationClassifiedBalanceSheetDisclosuresAbstract" xlink:label="loc_DisposalGroupIncludingDiscontinuedOperationClassifiedBalanceSheetDisclosuresAbstract"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentAssets" xlink:label="loc_DisposalGroupIncludingDiscontinuedOperationOtherCurrentAssets"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_AssetsAbstract"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="loc_AssetsOfDisposalGroupIncludingDiscontinuedOperation"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_LiabilitiesAndStockholdersEquityAbstract"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayable" xlink:label="loc_DisposalGroupIncludingDiscontinuedOperationAccountsPayable"/> |
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| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DisposalGroupIncludingDiscontinuedOperationAccruedExpensesAndOtherLiabilities" xlink:label="opk_DisposalGroupIncludingDiscontinuedOperationAccruedExpensesAndOtherLiabilities"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="loc_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DisposalGroupNotDiscontinuedOperationIncomeStatementDisclosuresAbstract" xlink:label="loc_DisposalGroupNotDiscontinuedOperationIncomeStatementDisclosuresAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:to="loc_DisposalGroupNotDiscontinuedOperationIncomeStatementDisclosuresAbstract" order="10" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationRevenue" xlink:label="loc_DisposalGroupIncludingDiscontinuedOperationRevenue"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DiscontinuedOperationProvisionForLossGainOnDisposalBeforeIncomeTax" xlink:label="loc_DiscontinuedOperationProvisionForLossGainOnDisposalBeforeIncomeTax"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DisposalGroupNotDiscontinuedOperationIncomeStatementDisclosuresAbstract" xlink:to="loc_DiscontinuedOperationProvisionForLossGainOnDisposalBeforeIncomeTax" order="60" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax" xlink:label="loc_IncomeLossFromDiscontinuedOperationsNetOfTax"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_DiscontinuedOperationsAndDisposalGroupsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DiscontinuedOperationsTextualAbstract" xlink:label="opk_DiscontinuedOperationsTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:to="opk_DiscontinuedOperationsTextualAbstract" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses" xlink:label="loc_ProceedsFromDivestitureOfBusinesses"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_DiscontinuedOperationsTextualAbstract" xlink:to="loc_ProceedsFromDivestitureOfBusinesses" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DisposalGroupIncludingDiscontinuedOperationReceivedRoyalties" xlink:label="opk_DisposalGroupIncludingDiscontinuedOperationReceivedRoyalties"/> |
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| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/FairValueMeasurementsDetails" xlink:title="06071 - Disclosure - Fair Value Measurements (Details 1)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_FairValueDisclosuresAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTable" xlink:label="loc_ScheduleOfCashAndCashEquivalentsTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="loc_ScheduleOfCashAndCashEquivalentsTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_FairValueByFairValueHierarchyLevelAxis"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_FairValueInputsLevel1Member"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_FairValueInputsLevel2Member"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CashAndCashEquivalentsLineItems" xlink:label="loc_CashAndCashEquivalentsLineItems"/> |
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| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="loc_MoneyMarketFundsMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_USTreasurySecuritiesMember" xlink:label="loc_USTreasurySecuritiesMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="loc_USTreasurySecuritiesMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StockOptionsMember" xlink:label="loc_StockOptionsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="loc_StockOptionsMember" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_WarrantMember" xlink:label="loc_WarrantMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="loc_WarrantMember" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueByLiabilityClassAxis" xlink:label="loc_FairValueByLiabilityClassAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfCashAndCashEquivalentsTable" xlink:to="loc_FairValueByLiabilityClassAxis" order="32.5" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:label="loc_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByLiabilityClassAxis" xlink:to="loc_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ContingentConsiderationClassifiedAsEquityMember" xlink:label="loc_ContingentConsiderationClassifiedAsEquityMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:to="loc_ContingentConsiderationClassifiedAsEquityMember" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BzneNoteAndBeneficialConversationFeatureMember" xlink:label="opk_BzneNoteAndBeneficialConversationFeatureMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="opk_BzneNoteAndBeneficialConversationFeatureMember" order="85" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FinetechContingentConsiderationMember" xlink:label="opk_FinetechContingentConsiderationMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:to="opk_FinetechContingentConsiderationMember" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CertificatesOfDepositMember" xlink:label="loc_CertificatesOfDepositMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="loc_CertificatesOfDepositMember" order="82.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CommonStockInvestmentsMember" xlink:label="opk_CommonStockInvestmentsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="opk_CommonStockInvestmentsMember" order="83.75" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OpkoContigentConsiderationMember" xlink:label="opk_OpkoContigentConsiderationMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:to="opk_OpkoContigentConsiderationMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FarmadietContingentConsiderationMember" xlink:label="opk_FarmadietContingentConsiderationMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:to="opk_FarmadietContingentConsiderationMember" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DeferredAcquisitionPaymentsNetOfDiscountMember" xlink:label="opk_DeferredAcquisitionPaymentsNetOfDiscountMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain" xlink:to="opk_DeferredAcquisitionPaymentsNetOfDiscountMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ForwardContractsMember" xlink:label="us-gaap_ForwardContractsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="us-gaap_ForwardContractsMember" order="83.125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/FairValueMeasurementsDetailsTextual" xlink:title="06073 - Disclosure - Fair Value Measurements (Details Textual)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_FairValueDisclosuresAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTable" xlink:label="loc_ScheduleOfCashAndCashEquivalentsTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="loc_ScheduleOfCashAndCashEquivalentsTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_USTreasurySecuritiesMember" xlink:label="loc_USTreasurySecuritiesMember"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueByAssetClassAxis" xlink:label="loc_FairValueByAssetClassAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfCashAndCashEquivalentsTable" xlink:to="loc_FairValueByAssetClassAxis" order="15" use="optional" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:label="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByAssetClassAxis" xlink:to="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" order="20" use="optional"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="loc_USTreasurySecuritiesMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CashAndCashEquivalentsLineItems" xlink:label="loc_CashAndCashEquivalentsLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfCashAndCashEquivalentsTable" xlink:to="loc_CashAndCashEquivalentsLineItems" order="17.5" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FairValueMeasurementsTextualAbstract" xlink:label="opk_FairValueMeasurementsTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_CashAndCashEquivalentsLineItems" xlink:to="opk_FairValueMeasurementsTextualAbstract" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_MaturityDateOfSecurity" xlink:label="opk_MaturityDateOfSecurity"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_FairValueMeasurementsTextualAbstract" xlink:to="opk_MaturityDateOfSecurity" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_TreasuryStockValue" xlink:label="loc_TreasuryStockValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_FairValueMeasurementsTextualAbstract" xlink:to="loc_TreasuryStockValue" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionContingentConsiderationAtFairValue" xlink:label="loc_BusinessAcquisitionContingentConsiderationAtFairValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_FairValueMeasurementsTextualAbstract" xlink:to="loc_BusinessAcquisitionContingentConsiderationAtFairValue" order="90" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccruedLiabilities" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccruedLiabilities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_FairValueMeasurementsTextualAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccruedLiabilities" order="110" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationOtherNoncurrentLiabilities" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationOtherNoncurrentLiabilities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_FairValueMeasurementsTextualAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationOtherNoncurrentLiabilities" order="130" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/DerivativeContractsDetails" xlink:title="0608 - Disclosure - Derivative Contracts (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="loc_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:to="loc_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_DerivativeInstrumentRiskAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:to="loc_DerivativeInstrumentRiskAxis" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_DerivativeContractTypeDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeInstrumentRiskAxis" xlink:to="loc_DerivativeContractTypeDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="loc_DerivativeInstrumentsGainLossLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:to="loc_DerivativeInstrumentsGainLossLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ZeroToThirtyMember" xlink:label="opk_ZeroToThirtyMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeContractTypeDomain" xlink:to="opk_ZeroToThirtyMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ThirtyOneToSixtyMember" xlink:label="opk_ThirtyOneToSixtyMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeContractTypeDomain" xlink:to="opk_ThirtyOneToSixtyMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_SixtyOneToNinetyMember" xlink:label="opk_SixtyOneToNinetyMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeContractTypeDomain" xlink:to="opk_SixtyOneToNinetyMember" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NinetyOneToOneHundredTwentyMember" xlink:label="opk_NinetyOneToOneHundredTwentyMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeContractTypeDomain" xlink:to="opk_NinetyOneToOneHundredTwentyMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OneHundredTwentyOneToOneHundredEightyMember" xlink:label="opk_OneHundredTwentyOneToOneHundredEightyMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeContractTypeDomain" xlink:to="opk_OneHundredTwentyOneToOneHundredEightyMember" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_MoreThanOneHundredEightyMember" xlink:label="opk_MoreThanOneHundredEightyMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeContractTypeDomain" xlink:to="opk_MoreThanOneHundredEightyMember" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ForeignCurrencyDerivativesAbstract" xlink:label="loc_ForeignCurrencyDerivativesAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_DerivativeInstrumentsGainLossLineItems" xlink:to="loc_ForeignCurrencyDerivativesAbstract" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_NotionalAmountOfForeignCurrencyDerivatives" xlink:label="loc_NotionalAmountOfForeignCurrencyDerivatives"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ForeignCurrencyDerivativesAbstract" xlink:to="loc_NotionalAmountOfForeignCurrencyDerivatives" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ForeignCurrencyDerivativesAtFairValueNet" xlink:label="loc_ForeignCurrencyDerivativesAtFairValueNet"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ForeignCurrencyDerivativesAbstract" xlink:to="loc_ForeignCurrencyDerivativesAtFairValueNet" order="17.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_EffectOfLossOnForeignCurrencyDerivativeBeforeTax" xlink:label="opk_EffectOfLossOnForeignCurrencyDerivativeBeforeTax"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ForeignCurrencyDerivativesAbstract" xlink:to="opk_EffectOfLossOnForeignCurrencyDerivativeBeforeTax" order="25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/CommitmentsAndContingenciesDetailsTextual" xlink:title="0610 - Disclosure - Commitments and Contingencies (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_CommitmentsAndContingenciesDisclosureAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_CommitmentsAndContingenciesDisclosureAbstract" xlink:to="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" order="2.5" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_BusinessAcquisitionAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_BusinessAcquisitionAxis" order="30" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_BusinessAcquisitionAcquireeDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAxis" xlink:to="loc_BusinessAcquisitionAcquireeDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_BusinessAcquisitionLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_BusinessAcquisitionLineItems" order="60" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CurnaAcquisitionMember" xlink:label="opk_CurnaAcquisitionMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_CurnaAcquisitionMember" order="65" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionContingentConsiderationAtFairValue" xlink:label="loc_BusinessAcquisitionContingentConsiderationAtFairValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionLineItems" xlink:to="loc_BusinessAcquisitionContingentConsiderationAtFairValue" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CommitmentsAndContingenciesTextualAbstract" xlink:label="opk_CommitmentsAndContingenciesTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_CommitmentsAndContingenciesDisclosureAbstract" xlink:to="opk_CommitmentsAndContingenciesTextualAbstract" order="22.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccruedLiabilities" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccruedLiabilities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_CommitmentsAndContingenciesTextualAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccruedLiabilities" order="11.25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationOtherNoncurrentLiabilities" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationOtherNoncurrentLiabilities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_CommitmentsAndContingenciesTextualAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationOtherNoncurrentLiabilities" order="12.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/SegmentsDetails" xlink:title="0611 - Disclosure - Segments (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_SegmentReportingAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" xlink:label="loc_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentReportingAbstract" xlink:to="loc_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StatementGeographicalAxis" xlink:label="loc_StatementGeographicalAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" xlink:to="loc_StatementGeographicalAxis" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentGeographicalDomain" xlink:label="loc_SegmentGeographicalDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementGeographicalAxis" xlink:to="loc_SegmentGeographicalDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems" xlink:label="loc_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" xlink:to="loc_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SalesRevenueServicesNetAbstract" xlink:label="loc_SalesRevenueServicesNetAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems" xlink:to="loc_SalesRevenueServicesNetAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SalesRevenueGoodsNet" xlink:label="loc_SalesRevenueGoodsNet"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SalesRevenueServicesNetAbstract" xlink:to="loc_SalesRevenueGoodsNet" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.sec.gov/country/2012/country-2012-01-31.xsd#country_CL" xlink:label="loc_CL"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentGeographicalDomain" xlink:to="loc_CL" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.sec.gov/country/2012/country-2012-01-31.xsd#country_MX" xlink:label="loc_MX"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentGeographicalDomain" xlink:to="loc_MX" order="50" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.sec.gov/country/2012/country-2012-01-31.xsd#country_US" xlink:label="loc_US"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentGeographicalDomain" xlink:to="loc_US" order="15" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_StatementBusinessSegmentsAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" xlink:to="loc_StatementBusinessSegmentsAxis" order="30" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_SegmentDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementBusinessSegmentsAxis" xlink:to="loc_SegmentDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_OperatingSegmentsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentDomain" xlink:to="loc_OperatingSegmentsMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CorporateMember" xlink:label="loc_CorporateMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentDomain" xlink:to="loc_CorporateMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DiscontinuedOperationsMember" xlink:label="opk_DiscontinuedOperationsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentDomain" xlink:to="opk_DiscontinuedOperationsMember" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SalesRevenueServicesNetAbstract" xlink:to="loc_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_DepreciationDepletionAndAmortization"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SalesRevenueServicesNetAbstract" xlink:to="loc_DepreciationDepletionAndAmortization" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_Assets" xlink:label="loc_Assets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SalesRevenueServicesNetAbstract" xlink:to="loc_Assets" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.sec.gov/country/2012/country-2012-01-31.xsd#country_IL" xlink:label="loc_IL"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentGeographicalDomain" xlink:to="loc_IL" order="45" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.sec.gov/country/2012/country-2012-01-31.xsd#country_ES" xlink:label="country_ES"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentGeographicalDomain" xlink:to="country_ES" order="35" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/SegmentsDetailsTextual" xlink:title="06111 - Disclosure - Segments (Details Textual)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_SegmentReportingAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable" xlink:label="loc_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_SegmentReportingAbstract" xlink:to="loc_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable" order="10" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_MajorCustomersAxis" xlink:label="loc_MajorCustomersAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable" xlink:to="loc_MajorCustomersAxis" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_NameOfMajorCustomerDomain" xlink:label="loc_NameOfMajorCustomerDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_MajorCustomersAxis" xlink:to="loc_NameOfMajorCustomerDomain" order="10" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EntityWideRevenueMajorCustomerLineItems" xlink:label="loc_EntityWideRevenueMajorCustomerLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable" xlink:to="loc_EntityWideRevenueMajorCustomerLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_SegmentsTextualAbstract" xlink:label="opk_SegmentsTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_EntityWideRevenueMajorCustomerLineItems" xlink:to="opk_SegmentsTextualAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AccountsReceivableFromMajorCustomer" xlink:label="opk_AccountsReceivableFromMajorCustomer"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_SegmentsTextualAbstract" xlink:to="opk_AccountsReceivableFromMajorCustomer" order="18.125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CustomerOneMember" xlink:label="opk_CustomerOneMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_NameOfMajorCustomerDomain" xlink:to="opk_CustomerOneMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EntityWideRevenueMajorCustomerPercentage" xlink:label="loc_EntityWideRevenueMajorCustomerPercentage"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_SegmentsTextualAbstract" xlink:to="loc_EntityWideRevenueMajorCustomerPercentage" order="12.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfReportableSegment" xlink:label="opk_NumberOfReportableSegment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_SegmentsTextualAbstract" xlink:to="opk_NumberOfReportableSegment" order="6.25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfOperatingSegment" xlink:label="opk_NumberOfOperatingSegment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_SegmentsTextualAbstract" xlink:to="opk_NumberOfOperatingSegment" order="9.375" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfCustomerRepresentation" xlink:label="opk_NumberOfCustomerRepresentation"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_SegmentsTextualAbstract" xlink:to="opk_NumberOfCustomerRepresentation" order="38.125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PercentageOfCustomerInTotalRevenue" xlink:label="opk_PercentageOfCustomerInTotalRevenue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_SegmentsTextualAbstract" xlink:to="opk_PercentageOfCustomerInTotalRevenue" order="58.125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/BalanceSheetsParenthetical" xlink:title="0111 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) (unaudited)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_StatementOfFinancialPositionAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_StatementTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementOfFinancialPositionAbstract" xlink:to="loc_StatementTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_StatementLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementTable" xlink:to="loc_StatementLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_TemporaryEquityParOrStatedValuePerShare" xlink:label="loc_TemporaryEquityParOrStatedValuePerShare"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementLineItems" xlink:to="loc_TemporaryEquityParOrStatedValuePerShare" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_TemporaryEquitySharesAuthorized" xlink:label="loc_TemporaryEquitySharesAuthorized"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementLineItems" xlink:to="loc_TemporaryEquitySharesAuthorized" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_TemporaryEquitySharesIssued" xlink:label="loc_TemporaryEquitySharesIssued"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementLineItems" xlink:to="loc_TemporaryEquitySharesIssued" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_TemporaryEquitySharesOutstanding" xlink:label="loc_TemporaryEquitySharesOutstanding"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementLineItems" xlink:to="loc_TemporaryEquitySharesOutstanding" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_TemporaryEquityLiquidationPreference" xlink:label="loc_TemporaryEquityLiquidationPreference"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_StatementLineItems" xlink:to="loc_TemporaryEquityLiquidationPreference" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SeriesAPreferredStockMember" xlink:label="loc_SeriesAPreferredStockMember"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SeriesCPreferredStockMember" xlink:label="loc_SeriesCPreferredStockMember"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ProvisionForDoubtfulAccounts" xlink:label="loc_ProvisionForDoubtfulAccounts"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_LicensesRevenue" xlink:label="loc_LicensesRevenue"/> |
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| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock" xlink:label="loc_BusinessCombinationDisclosureTextBlock"/> |
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| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:to="loc_BusinessAcquisitionLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionLineItems" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ClarosDiagnosticsMember" xlink:label="opk_ClarosDiagnosticsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionAcquireeDomain" xlink:to="opk_ClarosDiagnosticsMember" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityPurchasePrice" order="170" use="optional" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionContingentConsiderationAtFairValue" xlink:label="loc_BusinessAcquisitionContingentConsiderationAtFairValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionContingentConsiderationAtFairValue" order="165" use="optional" preferredLabel="http://xbrl.us/us-gaap/role/label/negated"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationDeferredIncomeTaxesAssetLiabilityNet" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationDeferredIncomeTaxesAssetLiabilityNet"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationDeferredIncomeTaxesAssetLiabilityNet" order="162.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccountsPayableAndAccruedExpenses" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccountsPayableAndAccruedExpenses"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationCurrentLiabilitiesAccountsPayableAndAccruedExpenses" order="161.25" use="optional" preferredLabel="http://xbrl.us/us-gaap/role/label/negated"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationOtherAssets" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationOtherAssets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationOtherAssets" order="160.625" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationGoodwillAmount" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationGoodwillAmount"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationGoodwillAmount" order="160.15625" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionPurchasePriceAllocationTechnology" xlink:label="opk_BusinessAcquisitionPurchasePriceAllocationTechnology"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="opk_BusinessAcquisitionPurchasePriceAllocationTechnology" order="160.078125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationCurrentAssets" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationCurrentAssets"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationCurrentAssets" order="160.0390625" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationEquipment" xlink:label="loc_BusinessAcquisitionPurchasePriceAllocationEquipment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_BusinessAcquisitionPurchasePriceAllocationAbstract" xlink:to="loc_BusinessAcquisitionPurchasePriceAllocationEquipment" order="160.2344" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/FairValueMeasurementsDetails1" xlink:title="0607 - Disclosure - Fair Value Measurements (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_FairValueDisclosuresAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueByBalanceSheetGroupingTable" xlink:label="loc_FairValueByBalanceSheetGroupingTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="loc_FairValueByBalanceSheetGroupingTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_FairValueByFairValueHierarchyLevelAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByBalanceSheetGroupingTable" xlink:to="loc_FairValueByFairValueHierarchyLevelAxis" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_FairValueMeasurementsFairValueHierarchyDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByFairValueHierarchyLevelAxis" xlink:to="loc_FairValueMeasurementsFairValueHierarchyDomain" order="20" use="optional" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CommonStockInvestmentsMember" xlink:label="opk_CommonStockInvestmentsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueMeasurementsFairValueHierarchyDomain" xlink:to="opk_CommonStockInvestmentsMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BzneNoteAndBeneficialConversationFeatureMember" xlink:label="opk_BzneNoteAndBeneficialConversationFeatureMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueMeasurementsFairValueHierarchyDomain" xlink:to="opk_BzneNoteAndBeneficialConversationFeatureMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StockOptionsMember" xlink:label="loc_StockOptionsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueMeasurementsFairValueHierarchyDomain" xlink:to="loc_StockOptionsMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_WarrantMember" xlink:label="loc_WarrantMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueMeasurementsFairValueHierarchyDomain" xlink:to="loc_WarrantMember" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:label="loc_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByBalanceSheetGroupingTable" xlink:to="loc_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract" xlink:label="loc_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:to="loc_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAmortizedCost" xlink:label="loc_AvailableForSaleSecuritiesAmortizedCost"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract" xlink:to="loc_AvailableForSaleSecuritiesAmortizedCost" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableforsaleSecuritiesGrossUnrealizedGain" xlink:label="loc_AvailableforsaleSecuritiesGrossUnrealizedGain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract" xlink:to="loc_AvailableforsaleSecuritiesGrossUnrealizedGain" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableForSaleSecuritiesGrossUnrealizedLosses1" xlink:label="loc_AvailableForSaleSecuritiesGrossUnrealizedLosses1"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract" xlink:to="loc_AvailableForSaleSecuritiesGrossUnrealizedLosses1" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableForSaleSecuritiesFairValueDisclosure" xlink:label="loc_AvailableForSaleSecuritiesFairValueDisclosure"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract" xlink:to="loc_AvailableForSaleSecuritiesFairValueDisclosure" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AvailableForSaleSecuritiesGrossUnrealizedGainLoss" xlink:label="us-gaap_AvailableForSaleSecuritiesGrossUnrealizedGainLoss"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AvailableForSaleSecuritiesBalanceSheetReportedAmountsAbstract" xlink:to="us-gaap_AvailableForSaleSecuritiesGrossUnrealizedGainLoss" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/RelatedPartyTransactionsDetails" xlink:title="0609 - Disclosure - Related Party Transactions (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="loc_RelatedPartyTransactionsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyTransactionsAbstract" xlink:to="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" order="5" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RelatedPartyTransactionAxis" xlink:label="opk_RelatedPartyTransactionAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:to="opk_RelatedPartyTransactionAxis" order="10" use="optional" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RelatedPartyTransactionDomain" xlink:label="opk_RelatedPartyTransactionDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionAxis" xlink:to="opk_RelatedPartyTransactionDomain" order="20" use="optional" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ManagementOneMember" xlink:label="opk_ManagementOneMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionDomain" xlink:to="opk_ManagementOneMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ManagementTwoMember" xlink:label="opk_ManagementTwoMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionDomain" xlink:to="opk_ManagementTwoMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ManagementFourMember" xlink:label="opk_ManagementFourMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionDomain" xlink:to="opk_ManagementFourMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_MrPregoNovoMember" xlink:label="opk_MrPregoNovoMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionDomain" xlink:to="opk_MrPregoNovoMember" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_RelatedPartyTransactionsByRelatedPartyAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:to="loc_RelatedPartyTransactionsByRelatedPartyAxis" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_RelatedPartyDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyTransactionsByRelatedPartyAxis" xlink:to="loc_RelatedPartyDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_GammaTrustMember" xlink:label="opk_GammaTrustMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_GammaTrustMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_HsuGammaMember" xlink:label="opk_HsuGammaMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_HsuGammaMember" order="25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_SorrentoMember" xlink:label="opk_SorrentoMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_SorrentoMember" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_GammaTrustAndHsuGammaMember" xlink:label="opk_GammaTrustAndHsuGammaMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_GammaTrustAndHsuGammaMember" order="50" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DrRichardLernerMember" xlink:label="opk_DrRichardLernerMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_DrRichardLernerMember" order="130" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TrsiMember" xlink:label="opk_TrsiMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_TrsiMember" order="140" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RealEstateHoldingsLlcMember" xlink:label="opk_RealEstateHoldingsLlcMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_RealEstateHoldingsLlcMember" order="160" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ChromadexCorporationMember" xlink:label="opk_ChromadexCorporationMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_ChromadexCorporationMember" order="200" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BiozonePharmaceuticalsIncMember" xlink:label="opk_BiozonePharmaceuticalsIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_BiozonePharmaceuticalsIncMember" order="220" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AeroPharmaceuticalsIncMember" xlink:label="opk_AeroPharmaceuticalsIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_AeroPharmaceuticalsIncMember" order="240" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="loc_RelatedPartyTransactionLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:to="loc_RelatedPartyTransactionLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RelatedPartyTransactionsTextualAbstract" xlink:label="opk_RelatedPartyTransactionsTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyTransactionLineItems" xlink:to="opk_RelatedPartyTransactionsTextualAbstract" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestments" xlink:label="loc_EquityMethodInvestments"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_EquityMethodInvestments" order="5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OwnershipPercentageHeldByMembers" xlink:label="opk_OwnershipPercentageHeldByMembers"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_OwnershipPercentageHeldByMembers" order="25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuableParValue" xlink:label="opk_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuableParValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_BusinessAcquisitionCostOfAcquiredEntityEquityInterestsIssuedAndIssuableParValue" order="37.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PromissoryNotesMaturityDate" xlink:label="opk_PromissoryNotesMaturityDate"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_PromissoryNotesMaturityDate" order="38.125" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_WarrantsDuration" xlink:label="opk_WarrantsDuration"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_WarrantsDuration" order="38.4375" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_WarrantsToPurchaseCommonShares" xlink:label="opk_WarrantsToPurchaseCommonShares"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_WarrantsToPurchaseCommonShares" order="38.59375" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ExercisePriceOfWarrantsAcquiredInEquityMethodInvestment" xlink:label="opk_ExercisePriceOfWarrantsAcquiredInEquityMethodInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_ExercisePriceOfWarrantsAcquiredInEquityMethodInvestment" order="38.67188" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_CommonStockSharesIssued"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_CommonStockSharesIssued" order="38.71094" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:label="loc_EquityMethodInvestmentOwnershipPercentage"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_EquityMethodInvestmentOwnershipPercentage" order="39.35547" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_MaximumOwnershipPercentageHeldByMembers" xlink:label="opk_MaximumOwnershipPercentageHeldByMembers"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_MaximumOwnershipPercentageHeldByMembers" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_StockIssuedDuringPeriodSharesNewIssues"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_StockIssuedDuringPeriodSharesNewIssues" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_StockIssuedDuringPeriodValueNewIssues"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_StockIssuedDuringPeriodValueNewIssues" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity" xlink:label="loc_LineOfCreditFacilityRemainingBorrowingCapacity"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_LineOfCreditFacilityRemainingBorrowingCapacity" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_LineOfCreditFacilityPeriodicPaymentPrincipal" xlink:label="loc_LineOfCreditFacilityPeriodicPaymentPrincipal"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_LineOfCreditFacilityPeriodicPaymentPrincipal" order="120" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_LineOfCreditFacilityPeriodicPaymentInterest" xlink:label="loc_LineOfCreditFacilityPeriodicPaymentInterest"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_LineOfCreditFacilityPeriodicPaymentInterest" order="140" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_LineOfCreditFacilityInterestRateAtPeriodEnd" xlink:label="loc_LineOfCreditFacilityInterestRateAtPeriodEnd"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_LineOfCreditFacilityInterestRateAtPeriodEnd" order="220" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OwnershipPercentageHeldByDirector" xlink:label="opk_OwnershipPercentageHeldByDirector"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_OwnershipPercentageHeldByDirector" order="230" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AreaForMolecularDiagnosticsOperations" xlink:label="opk_AreaForMolecularDiagnosticsOperations"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_AreaForMolecularDiagnosticsOperations" order="240" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_GrossRentIsForTwoYearTerm" xlink:label="opk_GrossRentIsForTwoYearTerm"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_GrossRentIsForTwoYearTerm" order="260" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TermOfUseOfSpaceToHouseMolecularDiagnosticsOperations" xlink:label="opk_TermOfUseOfSpaceToHouseMolecularDiagnosticsOperations"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_TermOfUseOfSpaceToHouseMolecularDiagnosticsOperations" order="270" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AdditionalTermOfUseOfSpaceToHouseMolecularDiagnosticsOperations" xlink:label="opk_AdditionalTermOfUseOfSpaceToHouseMolecularDiagnosticsOperations"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_AdditionalTermOfUseOfSpaceToHouseMolecularDiagnosticsOperations" order="275" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_LicensingFeesPreviouslyPaid" xlink:label="opk_LicensingFeesPreviouslyPaid"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_LicensingFeesPreviouslyPaid" order="300" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_LicensingFeesPaid" xlink:label="opk_LicensingFeesPaid"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_LicensingFeesPaid" order="320" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ReimbursementOfCertainExpenses" xlink:label="opk_ReimbursementOfCertainExpenses"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_ReimbursementOfCertainExpenses" order="340" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OutstandingCommonSharesAcquired" xlink:label="opk_OutstandingCommonSharesAcquired"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_OutstandingCommonSharesAcquired" order="355" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_LeaseSpaceInOfficeBuildingHavingPrincipalOffice" xlink:label="opk_LeaseSpaceInOfficeBuildingHavingPrincipalOffice"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_LeaseSpaceInOfficeBuildingHavingPrincipalOffice" order="360" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_LeaseRentPerMonthForFirstYear" xlink:label="opk_LeaseRentPerMonthForFirstYear"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_LeaseRentPerMonthForFirstYear" order="380" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_LeaseRentPerMonthForFifthYear" xlink:label="opk_LeaseRentPerMonthForFifthYear"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_LeaseRentPerMonthForFifthYear" order="400" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CreditForTenantImprovements" xlink:label="opk_CreditForTenantImprovements"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_CreditForTenantImprovements" order="420" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:label="opk_RelatedPartyTransactionsAdditionalTextualAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyTransactionsAbstract" xlink:to="opk_RelatedPartyTransactionsAdditionalTextualAbstract" order="25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityCashPaid" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityCashPaid"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityCashPaid" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurred" xlink:label="loc_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurred"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="loc_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurred" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurredPaidAtClosing" xlink:label="opk_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurredPaidAtClosing"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_BusinessAcquisitionCostOfAcquiredEntityLiabilitiesIncurredPaidAtClosing" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TimeOfTransactionPercentageOwned" xlink:label="opk_TimeOfTransactionPercentageOwned"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_TimeOfTransactionPercentageOwned" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ResearchAndDevelopmentAgreementAmountForPeriod" xlink:label="opk_ResearchAndDevelopmentAgreementAmountForPeriod"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_ResearchAndDevelopmentAgreementAmountForPeriod" order="160" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfLicenseAgreements" xlink:label="opk_NumberOfLicenseAgreements"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_NumberOfLicenseAgreements" order="180" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AgreementPursuantToWhichInvested" xlink:label="opk_AgreementPursuantToWhichInvested"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_AgreementPursuantToWhichInvested" order="200" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfConvertibleSeriesPreferredStockHeldFromAgreement" xlink:label="opk_NumberOfConvertibleSeriesPreferredStockHeldFromAgreement"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_NumberOfConvertibleSeriesPreferredStockHeldFromAgreement" order="210" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_PreviousInvestmentByGroupOfInvestor" xlink:label="opk_PreviousInvestmentByGroupOfInvestor"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_PreviousInvestmentByGroupOfInvestor" order="240" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AdditionalInvestmentByGroupOfInvestor" xlink:label="opk_AdditionalInvestmentByGroupOfInvestor"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_AdditionalInvestmentByGroupOfInvestor" order="260" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_NumberOfEqualInstallmentsPayableForAdditionalInvestment" xlink:label="opk_NumberOfEqualInstallmentsPayableForAdditionalInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_NumberOfEqualInstallmentsPayableForAdditionalInvestment" order="272.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FirstInstallmentInvestment" xlink:label="opk_FirstInstallmentInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_FirstInstallmentInvestment" order="290" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AgreementToLeaseSpaceToHouseManufacturing" xlink:label="opk_AgreementToLeaseSpaceToHouseManufacturing"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_AgreementToLeaseSpaceToHouseManufacturing" order="300" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AdditionalAgreementToLeaseSpaceToHouseManufacturing" xlink:label="opk_AdditionalAgreementToLeaseSpaceToHouseManufacturing"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_AdditionalAgreementToLeaseSpaceToHouseManufacturing" order="320" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_GrossRentPayableUnderLease" xlink:label="opk_GrossRentPayableUnderLease"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_GrossRentPayableUnderLease" order="340" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ReimbursementPaidToRelatedPartyForTravel" xlink:label="opk_ReimbursementPaidToRelatedPartyForTravel"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_ReimbursementPaidToRelatedPartyForTravel" order="380" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_OwnershipPercentageHeld" xlink:label="opk_OwnershipPercentageHeld"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_OwnershipPercentageHeld" order="32.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_LoanToBzne" xlink:label="opk_LoanToBzne"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_LoanToBzne" order="190" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_SalesRevenueNet" xlink:label="loc_SalesRevenueNet"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_SalesRevenueNet" order="2.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TevaPharmaceuticalIndustriesMember" xlink:label="opk_TevaPharmaceuticalIndustriesMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_RelatedPartyDomain" xlink:to="opk_TevaPharmaceuticalIndustriesMember" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_VariableInterestEntityOwnershipPercentage" xlink:label="loc_VariableInterestEntityOwnershipPercentage"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="loc_VariableInterestEntityOwnershipPercentage" order="440" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FinancingForVariableInterestEntities" xlink:label="opk_FinancingForVariableInterestEntities"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsTextualAbstract" xlink:to="opk_FinancingForVariableInterestEntities" order="225" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RelatedPartyAffliatesAxis" xlink:label="opk_RelatedPartyAffliatesAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:to="opk_RelatedPartyAffliatesAxis" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/label" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_RelatedPartyAffliatesDomain" xlink:label="opk_RelatedPartyAffliatesDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyAffliatesAxis" xlink:to="opk_RelatedPartyAffliatesDomain" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/label" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FabrusIncMember" xlink:label="opk_FabrusIncMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyAffliatesDomain" xlink:to="opk_FabrusIncMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ManagementFiveMember" xlink:label="opk_ManagementFiveMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyAffliatesDomain" xlink:to="opk_ManagementFiveMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ManagementSixMember" xlink:label="opk_ManagementSixMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyAffliatesDomain" xlink:to="opk_ManagementSixMember" order="60" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ManagementEightMember" xlink:label="opk_ManagementEightMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyAffliatesDomain" xlink:to="opk_ManagementEightMember" order="80" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ManagementSevenMember" xlink:label="opk_ManagementSevenMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyAffliatesDomain" xlink:to="opk_ManagementSevenMember" order="100" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_FundForResearchAgreement" xlink:label="opk_FundForResearchAgreement"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_FundForResearchAgreement" order="140" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ResearchAgreementMaturityPeriod" xlink:label="opk_ResearchAgreementMaturityPeriod"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="opk_ResearchAgreementMaturityPeriod" order="150" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_DescriptionOfRelatedPartyLeasingArrangements" xlink:label="us-gaap_DescriptionOfRelatedPartyLeasingArrangements"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_RelatedPartyTransactionsAdditionalTextualAbstract" xlink:to="us-gaap_DescriptionOfRelatedPartyLeasingArrangements" order="400" use="optional" priority="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/FairValueMeasurementsDetails2" xlink:title="06072 - Disclosure - Fair Value Measurements (Details 2)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_FairValueDisclosuresAbstract"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueByBalanceSheetGroupingTable" xlink:label="loc_FairValueByBalanceSheetGroupingTable"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueDisclosuresAbstract" xlink:to="loc_FairValueByBalanceSheetGroupingTable" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis" xlink:label="loc_ContingentConsiderationByTypeAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByBalanceSheetGroupingTable" xlink:to="loc_ContingentConsiderationByTypeAxis" order="30" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain" xlink:label="loc_ContingentConsiderationTypeDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ContingentConsiderationByTypeAxis" xlink:to="loc_ContingentConsiderationTypeDomain" order="10" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_ContingentConsiderationMember" xlink:label="opk_ContingentConsiderationMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ContingentConsiderationTypeDomain" xlink:to="opk_ContingentConsiderationMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:label="loc_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByBalanceSheetGroupingTable" xlink:to="loc_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" order="40" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract" xlink:label="loc_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:to="loc_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue" xlink:label="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract" xlink:to="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue" order="15" use="optional" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_AdditionsToReconciliationOfFairValueMeasurement" xlink:label="opk_AdditionsToReconciliationOfFairValueMeasurement"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract" xlink:to="opk_AdditionsToReconciliationOfFairValueMeasurement" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisGainLossIncludedInEarningsAbstract" xlink:label="loc_FairValueAssetsMeasuredOnRecurringBasisGainLossIncludedInEarningsAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract" xlink:to="loc_FairValueAssetsMeasuredOnRecurringBasisGainLossIncludedInEarningsAbstract" order="35" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInEarnings1" xlink:label="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInEarnings1"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisGainLossIncludedInEarningsAbstract" xlink:to="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetGainLossIncludedInEarnings1" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisGainLossIncludedInOtherComprehensiveIncomeLoss" xlink:label="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisGainLossIncludedInOtherComprehensiveIncomeLoss"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisGainLossIncludedInEarningsAbstract" xlink:to="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisGainLossIncludedInOtherComprehensiveIncomeLoss" order="30" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_DeferredAcquisitionPaymentsNetOfDiscountMember" xlink:label="opk_DeferredAcquisitionPaymentsNetOfDiscountMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ContingentConsiderationTypeDomain" xlink:to="opk_DeferredAcquisitionPaymentsNetOfDiscountMember" order="40" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTax"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisGainLossIncludedInEarningsAbstract" xlink:to="us-gaap_OtherComprehensiveIncomeLossNetOfTax" order="31.25" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_TransferOutToEquityMethodInvestment" xlink:label="opk_TransferOutToEquityMethodInvestment"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract" xlink:to="opk_TransferOutToEquityMethodInvestment" order="55" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue" xlink:label="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_1"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssumptionsAndMethodologyForAssetsAndLiabilitiesAbstract" xlink:to="loc_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetValue_1" order="75" use="optional" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueByAssetClassAxis" xlink:label="loc_FairValueByAssetClassAxis"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByBalanceSheetGroupingTable" xlink:to="loc_FairValueByAssetClassAxis" order="35" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:label="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueByAssetClassAxis" xlink:to="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" order="20" use="optional"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_BnzeNoteAndBnzeWarrantsMember" xlink:label="opk_BnzeNoteAndBnzeWarrantsMember"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:to="opk_BnzeNoteAndBnzeWarrantsMember" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/CompositionOfCertainFinancialStatementCaptionsTables" xlink:title="0504 - Disclosure - Composition of Certain Financial Statement Captions (Tables)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CompositionOfCertainFinancialStatementCaptionsTableTextBlock" xlink:label="opk_CompositionOfCertainFinancialStatementCaptionsTableTextBlock"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="opk_CompositionOfCertainFinancialStatementCaptionsTableTextBlock" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | </presentationLink> |
| <presentationLink xlink:type="extended" xlink:role="http://opko.com/role/CompositionOfCertainFinancialStatementCaptionsDetails" xlink:title="0604 - Disclosure - Composition of Certain Financial Statement Captions (Details)"> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/> |
| | <loc xlink:type="locator" xlink:href="opk-20120930.xsd#opk_CompositionOfCertainFinancialStatementCaptionsAbstract" xlink:label="opk_CompositionOfCertainFinancialStatementCaptionsAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:to="opk_CompositionOfCertainFinancialStatementCaptionsAbstract" order="10" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AccountsReceivableNetAbstract" xlink:label="loc_AccountsReceivableNetAbstract"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="opk_CompositionOfCertainFinancialStatementCaptionsAbstract" xlink:to="loc_AccountsReceivableNetAbstract" order="20" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AccountsReceivableGrossCurrent" xlink:label="loc_AccountsReceivableGrossCurrent"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountsReceivableNetAbstract" xlink:to="loc_AccountsReceivableGrossCurrent" order="32.5" use="optional" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="1"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent" xlink:label="loc_AllowanceForDoubtfulAccountsReceivableCurrent"/> |
| | <presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_AccountsReceivableNetAbstract" xlink:to="loc_AllowanceForDoubtfulAccountsReceivableCurrent" order="33.75" use="optional" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/> |
| | <loc xlink:type="locator" xlink:href="http://xbrl.fasb.org/us-gaap/2012/elts/us-gaap-2012-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_AccountsReceivableNetCurrent"/> |
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